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EMBL Conference

Omics and Personalised Health

EMBL Heidelberg, Germany Thursday 16 February - Saturday 18 February 2012 Registration closed

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Day 1 - Thursday, 16 February 2012
11:00 - 13:00 Arrival & Registration
13:00 Opening Remarks
13:00-15:15 SESSION 1, Chair: Lars Steinmetz
13:15 'The EMBO Lecture':  Leroy Hood, Systems Approaches to Disease and the Emergence of Proactive P4 Medicine
14:15 Kelly Frazer, Identifying and Characterizing Risk Loci for Cardiovascular Diseases
14:45 Jan Korbel, Dissecting Genomic Structural Rearrangements in Childhood Medulloblastoma Genomes, with Implications for Patient Management
15:15 Coffee Break
15:45-18:30 SESSION 2, Chair: Michael Boutros
15:45 Peter Lichter, Oncogenomics of Pediatric Brain Tumors: Integrated Approaches allow Refinement of Molecular Subclassification and the Detection of Novel Pathomechanisms
16:15 Sven Bergmann, Integration of Large-Scale Molecular Phenotypes into Genome-Wide Association Studies
16:30 Adam Frankish (Jon Mudge), The Characterization of Functional Variation in the Context of Transcriptional Complexity
16:45 John Castle, Exploiting the Mutanome for Tumor Vaccination
17:00 Coffee Break
17:30 Cornelia van Duijn, From Genomics to Application
18:00 Greg Tyrelle, Genome-Wide Detection and Analysis of Germline and Somatic Variations
19:00 Dinner
21:00 Drinks at ATC Rooftop Lounge
Day 2 - Friday, 17 February 2012
09:30 - 12:00 SESSION 3: Chair: Jan Korbel
09:30 CANCELLED: Kari Stefansson, INSTEAD: Matthias Hentze, The Path towards Personalized Medicine:  How Diversity in the Sequence of the Nuclear Genome impacts Diversity in the Risks of Common /Complex Diseases
10:00 Stylianos Antonarakis,Trisomy 21: a Chromatin Disorder ?
10:30 Coffee Break
11:00 Peter Goldstein, Positional Sequencing: Characterizing Variation on all Genomic Length Scales, SNPs to Aneuploidies
11:30 CANCELLED: Olli Kallioniemi, Comprehensive Cancer-Omics Profiling and Ex Vivo Cellular Drug Sensitivity Testing
12:00 Lunch
13:30-16:15 SESSION 4: Chair: Rene Bernards
13:30 Rene Bernards, Finding Biomarkers of Response to Targeted Cancer Drugs Through Functional Genetics
14:00 Anne-Lise Børresen-Dale,Towards Integrated Genomics for Personalized Treatment of Breast Cancer
14:30 Peer Bork, Towards a Personal Gut Microbiome
15:00 Coffee Break
15:30 Jonathan Dry, Differentiating PI3K Isoform Specific Inhibition with Gene Expression
15:45 Raju Kandimalla, Genome-wide Analysis of CpG Island Methylation in Bladder Cancer Identifies Novel Biomarkers for Diagnosis and Prediction of Progression
16:00 Sander van Hooff, Validation of an Expression Signature for Lymph Node Metastasis Detection in Oral Cavity Squamous Cell Carcinoma
18:00-18:45 SESSION 5, Chair: Wolfgang Huber
18:00 Michael Boutros, Synthetic Genetic Interaction Analysis to map Cellular Networks
18:30 Ines Thiele, Functional Assessment of Omics Data using a Comprehensive Community Generated Reconstruction of Human Metabolism
18:45 Sandrine Ellero-Simatos, Urine Metabolomics Profiling in Healthy Volunteers treated with Prednisolone: New Insights into the Metabolic Effects of Glucocorticoid Drugs
19:00 Dinner
21:00 Drinks at ATC Rooftop Lounge
Day 3 - Saturday, 18 February 2012
09:30 - 12:00 SESSION 6, Chair: Rudi Balling
09:30 Lars Steinmetz, Systems Genetics in Yeast with Applications to Personalized Health
10:00 Wolfgang Huber, Genetic Interactions and Complex Phenotypes
10:30 Coffee Break
11:00 Robert Gentleman, How much can we learn from Current Genomic Approaches?
11:30 Tim Hubbard, From Genome Annotation to Genomic Medicine
12:00 Lunch
13:30-18:00 SESSION 7, Chair: Leroy Hood
13:30 Christof von Kalle, Translational Genome Sequencing in Clinical Oncology
14:00 John Overington, Efficacy and Safety of Therapeutics - Nature and Nurture
14:30 Daniel Mertens, Identification of candidate Therapeutic Inhibitors of the Microinvironmental Support of Leukemic Cells by Transcriptome Analysis
14:45 Coffee Break
15:15 Hank Greely, Genomics in Personalized Medicine:  Ethical, Legal, and Practical Problems
15:45 Anne Cambon-Thomson, The Ethics of Personomics
16:15 Panel Discussion Chair: Rudi Balling
Leroy Hood
Hank Greely
Christoph von Kalle
Robert Gentleman
Tim Hubbard
John Overington 
18:00 Posters with Wine & Cheese
19:00 Gala Dinner & Party

Omics and Personalised Health, 16 - 18 February 2012

Watch an interview with the organisers discussing their vision of the conference!