EMBO Conference Series
Chromatin and Epigenetics
EMBL Heidelberg, Germany Wednesday 8 May - Sunday 12 May 2013 Registration closedAbstract submission closed

Conference Programme
| Time | Speaker | Title |
|---|---|---|
| 15:00 - 17:15 |
RECEPTION AND REGISTRATION |
|
| 17:15 - 17:30 |
Opening remarks |
|
| 17:30 - 20:35 |
SESSION 1- From nucleosomes to systems |
Chairs: Peter Fraser and Jane Mellor |
| 17:30 - 17:55 |
Frank Pugh, Pennstate University, USA |
Interplay between chromatin and the transcription machinery |
| 17:55 - 18:10 |
Petra Hajkova, MRC Clinical Sciences Centre, United Kingdom |
The role of Tet3 driven 5mC hydroxylation in the mouse zygote |
| 18:10 - 18:25 |
Karsten Rippe, German Cancer Research Center (DKFZ) & BioQuant, Germany |
Specificity, propagation of histone modifications and epigenetic memory of pericentric heterochromatin in mouse fibroblasts |
| 18:25 - 18:50 | Amos Tanay, Weizmann Institute, Israel | DNA methylation: epigenetic memory or dynamic regulatory mark? |
| 18:50 - 19:20 | COFFEE BREAK | ATC Foyer |
| 19:20 - 19:45 |
Claudia Keller, Friedrich Miescher Institute for Biomedical Research, Switzerland |
Non-coding RNAs prevent spreading of a repressive histone mark |
| 19:45 - 20:10 |
Robert Martienssen, Cold Spring Harbor Laboratory, USA |
Inheritance and reprogramming of heterochromatin with small RNA |
| 20:10 - 20:35 |
Gary Karpen, Lawrence Berkeley National Laboratory, USA |
Heterochromatin proteins and nuclear pores regulate the spatial and temporal dynamics of recombination repair among repeated DNAs |
| 20:35 - 22:30 |
REFRESHMENTS in ATC Foyer |
| Time | Speaker | Title |
|---|---|---|
| 09.00 - 12.10 |
SESSION 2 - Comparative epigenomics |
Chairs: Jason Lieb and Denise Barlow |
| 09:00 - 09:25 |
Oliver Rando, University of Massachusetts Medical School, USA |
Fungal chromatin structure and function |
| 09:25 - 09:40 |
Philipp Steffen, IMBA - Institute of Molecular Biotechnology, Austria |
Retention of the Drosophila TrxG protein ASH1 on mitotic chromatin may act as bookmark for active gene expression states |
| 09:40 - 09:55 |
Julia Zeitlinger, Stowers Institute for Medical Research, USA |
Global recruitment of paused Pol II during the Drosophila maternal-to-zygotic transition |
| 09:55 - 10:20 |
Henk Stunnenberg, Nijmegen Centre for Molecular Life Sciences, The Netherlands |
The epigenome of groundstate mouse embryonic stem cells |
| 10:20 - 10:50 |
COFFEE BREAK |
ATC Foyer |
| 10:50 - 11:15 |
Tony Kouzarides, Gurdon Institute, University of Cambridge, United Kingdom |
Epigenetic pathways in transcription and cancer |
| 11:15 - 11:30 |
Crisanto Gutierrez, Centro de Biologia Molecular Severo Ochoa, CSIC-UAM, Spain |
Epigenomic landscapes of DNA replication origins in a live organism |
| 11:30 - 11:45 |
Constance Alabert, BRIC, Copenhagen University, Denmark |
Chromatin dynamics during DNA replication and new replication factors determined by Nascent Chromatin Capture (NCC) proteomics |
| 11:45 - 12:10 |
Bas van Steensel, The Netherlands Cancer Institute, The Netherlands |
Probing position effects in high throughput mode |
| 12:10 - 13:30 |
LUNCH |
EMBL Canteen |
| 13:30 - 16:00 |
POSTER SESSION I (abstracts 53- 138) |
Helix A |
| 16.00 - 19.10 |
SESSION 3 - Balancing the Genome |
Chairs: Asifa Akhtar and Craig Peterson |
| 16:00 - 16:25 |
Barbara Meyer, HHMI and University of California at Berkeley, USA |
Repressing chromosomes via molecular machines |
| 16:25 - 16:40 |
Ibrahim Avsar Ilik, Max-Planck Institute of Immunobiology and Epigenetics, Germany |
A tandem-stem RNA motif mediates X-chromosome dosage compensation in Drosophila |
| 16:40 - 16:55 |
Peter B. Becker, Ludwig Maximilians Universität, Germany |
A role for long, non-coding roX RNA for the biogenesis of the dosage compensation complex in Drosophila |
| 16:55 - 17:20 | Susan Strome, University of California, Santa Cruz, USA | X-Chromosome regulation in the germline of C. elegans |
| 17:20 - 17:50 |
COFFEE BREAK |
ATC Foyer |
| 17:50 - 18:15 |
Denise Barlow, CeMM Center for Molecular Medicine of the Austrian Academy of Sciences, Austria |
Gene silencing by macro lncRNA transcriptional interference |
| 18:15 - 18:30 |
Yehudit Bergman, The Hebrew University, Israel |
Allelic plasticity and commitment in the hematopoietic system |
| 18:30 - 18:45 |
Jop Kind, Netherlands Cancer Institute, The Netherlands |
Nuclear lamina – genome interactions in single cells |
| 18:45 - 19:10 |
Jason Lieb, The University of North Carolina at Chapel Hill, USA |
The nuclear envelope: A nexus for gene regulation |
| 19:10 - 20:30 |
DINNER |
EMBL Canteen |
| 20:30 - 21:30 |
BEER SESSION |
ATC Foyer and ATC Rooftop Lounge (top of Helix A) |
| Time | Speaker | Title |
|---|---|---|
| 09.00 - 12.10 |
SESSION 4 - Chromatin structure and organization in development |
Chairs: Barbara Meyer and Ali Shilatifard |
| 09:00 - 09:25 |
Anne Kathrin Voss, Walter and Eliza Hall Institute of Medical Research, Australia |
MYST lysine acetyltransferases in stem cell function and histone acetylation |
| 09:25 - 09:50 |
Christine Disteche, University of Washington, USA |
Upregulation of the mammalian X chromosome is associated with enhanced transcription initiation,MOF-mediated H4K16 acetylation, and longer RNA half-life |
| 09:50 - 10:05 |
Simao Teixeira da Rocha, Curie Institute, France |
Xist RNA dependent JARID2 recruitment is crucial for efficient PRC2 targeting to the inactive X-chromosome |
| 10:05 - 10:30 |
Asifa Akhtar, Max Planck Immunobiology and Epigenetics, Germany |
Epigenetic regulation by MSL proteins |
| 10:30 - 11:00 |
COFFEE BREAK |
ATC Foyer |
| 11:00 - 11:15 |
Marc Timmers, University Medical Center Utrecht, The Netherlands |
Nucleosomal DNA binding drives the recognition of H3K36 methylated nucleosomes by PWWP domains |
| 11:15 - 11:30 |
Katalin Fejes Toth, California Institute of Technology, USA |
Small-RNA guided epigenetic regulation of transposon expression in the Drosophila germline |
| 11:30 - 11:45 |
Ashby Morrison, Stanford University, USA |
Dynamic regulation of the INO80 chromatin-remodeling complex in global transcription |
| 11:45 - 12:00 |
Manolis Papamichos-Chronakis, Curie Institute, France |
Integration of the INO80 remodeling complex in the ubiquitin degradation pathway is essential for genome stability |
| 12:10 - 13:30 |
LUNCH |
ATC Foyer |
| 13:30 - 16.00 |
POSTER SESSION II (abstracts 139- 224 ) |
Helix A & B |
| 16:00 - 17:00 |
SESSION 5 - Keynote lecture:
Peter A. Jones, USC Norris Comprehensive Cancer Center, USA |
Cancer Epigenetics and Epigenetics: Two Sides of the Same Coin? |
| 17:00 |
FREE EVENING |
| Time | Speaker | Title |
|---|---|---|
| 09.00 - 12.05 |
SESSION 6 - Chromatin dynamics and inheritance |
Chairs: Wolf Reik and Maria Elena Torres-Padilla |
| 09:00 - 09:25 |
Geneviève Almouzni, CNRS/Curie Institute, France |
CenH3 misregulation impacts histone deposition dynamics in human cells |
| 09:25 - 09:50 |
David M. Gilbert, Florida State University, USA |
The Replication Domain Model: regulating replicon firing in the context of large scale chromatin architecture |
| 09:50 - 10:15 |
Craig Peterson, University of Massachusetts Medical School, USA |
A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme |
| 10:15 - 10:30 |
Robert Schneider, IGBMC, France |
A causative function of histone modifications in regulation of chromatin dynamics and transcription |
| 10:30 - 11:00 |
COFFEE BREAK |
ATC Foyer |
| 11:00 - 11:25 |
Ali Shilatifard, Stowers Institute for Medical Research, USA |
Chromosomal translocations and transcriptional elongation control in epigenetics and cancer |
| 11:25 - 11:50 |
Jane Mellor, University of Oxford, United Kingdom |
Antisense transcription resets the epigenetic status of genes via dynamic, acetylated chromatin |
| 11:50 - 12:05 |
David Tremethick, The Australian National University, Australia |
Different strategies utilizing histone variants to create an open and dynamic chromatin structure at the transcription start site and at exon-intron boundaries |
| 12:05 - 13:30 |
LUNCH |
EMBL Canteen |
| 13:30 - 16:00 |
POSTER SESSION III (abstracts 225- 308) |
Helix B |
| 16.00 - 19.25 |
SESSION 7- Chromatin plasticity |
Chairs: Geneviève Almouzni and Bas van Steensel |
| 16:00 - 16:25 |
Giacomo Cavalli, Centre National de la Recherche Scientifique, France |
Polycomb proteins and chromosome organization in fly development |
| 16:25 - 16:50 |
Jürg Müller, Max Planck Institute of Biochemistry, Germany |
Targeting and function of histone modifications |
| 16:50 - 17:05 |
Raphaël Margueron, Curie Institute/INSERM U934/CNRS UMR3215, France |
A new feedback loop regulates polycomb complex PRC2 |
| 17:05 - 17:35 |
COFFEE BREAK |
ATC Foyer |
| 17:35 - 18:00 |
Kevin Struhl, Harvard Medical School, USA |
Determinants of nucleosome positioning |
| 18:00 - 18:15 |
Lukasz M. Boryn, Research Institute of Molecular Pathology (IMP), Austria |
Direct and quantitative identification of enhancers in flies and human by STARR-seq |
| 18:15 - 18:30 |
Yad Ghavi-Helm, European Molecular Biology Laboratory, Germany |
A temporal view of three-dimensional enhancer interactions during embryonic development |
| 18:30 - 18:45 |
Aleksandra Pekowska, European Molecular Biology Laboratory, Germany |
Dynamic changes of the 3D chromatin interactome during cell differentiation |
| 18:45 - 19:00 | Myriam Ruault, Curie Institute, France | Sir3 mediates long-range chromosomal interactions in budding yeast |
| 19:00 - 19:25 | Peter Fraser, Babraham Institute, United Kingdom | The 3D path of DNA in chromosomes: the rise of active chromatin |
| 19:25 - 19:30 |
Poster prize announcements |
|
| 19:30 - 01:00 |
BANQUET DINNER AND PARTY |
EMBL Canteen and ATC Foyer |
| Time | Speaker | Title |
|---|---|---|
| 09.00 - 12.00 |
SESSION 8 - Nuclear Reprogramming |
Chairs: Yehudit Bergman and Giacomo Cavalli |
| 09:00 - 09:25 |
Wolf Reik, Babraham Institute, United Kingdom |
Epigenetic reprogramming in mammalian development |
| 09:25 - 09:50 |
Amanda Fisher, MRC Clinical Sciences Centre, United Kingdom |
Epigenetic reprogramming of somatic cells towards pluripotency |
| 09:50 - 10:05 |
Poster Prize short talk 1 |
|
| 10:05 - 10:35 |
COFFEE BREAK |
ATC Foyer |
| 10:35 - 10:50 |
Poster Prize short talk 2 |
|
| 10:50 - 11:15 |
Maria Elena Torres Padilla, Institute of Genetics and Molecular and Cellular Biology, France |
Epigenetic mechanisms of cell plasticity |
| 11:15 - 11:40 |
Anton Wutz, Swiss Federal Institute of Technology, Switzerland |
Gene dosage in mammals: Characterization of haploid embryonic stem cells |
| 11:40 - 12:00 |
Concluding remarks |
|
| 12:00 |
Packed LUNCH and DEPARTURE |
