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EMBO Conference Series

Chromatin and Epigenetics

EMBL Heidelberg, Germany Wednesday 8 May - Sunday 12 May 2013 Registration closed
Abstract submission closed

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Conference Programme

The 2013 conference programme and the poster listing is available for download HERE.
Day 1 - Wednesday, 8th May 2013
Time Speaker Title
15:00 - 17:15


17:15 - 17:30

Opening remarks

17:30 - 20:35

SESSION 1- From nucleosomes to systems

Chairs: Peter Fraser and Jane Mellor
17:30 - 17:55

Frank Pugh, Pennstate University, USA

Interplay between chromatin and the transcription machinery
17:55 - 18:10

Petra Hajkova, MRC Clinical Sciences Centre, United Kingdom

The role of Tet3 driven 5mC hydroxylation in the mouse zygote
18:10 - 18:25

Karsten Rippe, German Cancer Research Center (DKFZ) & BioQuant, Germany

Specificity, propagation of histone modifications and epigenetic memory of pericentric heterochromatin in mouse fibroblasts
18:25 - 18:50 Amos Tanay, Weizmann Institute, Israel DNA methylation: epigenetic memory or dynamic regulatory mark?
18:50 - 19:20 COFFEE BREAK ATC Foyer
19:20 - 19:45

Claudia Keller, Friedrich Miescher Institute for Biomedical Research, Switzerland

Non-coding RNAs prevent spreading of a repressive histone mark
19:45 - 20:10

Robert Martienssen, Cold Spring Harbor Laboratory, USA

Inheritance and reprogramming of heterochromatin with small RNA
 20:10 - 20:35

Gary Karpen, Lawrence Berkeley National Laboratory, USA

Heterochromatin proteins and nuclear pores regulate the spatial and temporal dynamics of recombination repair among repeated DNAs
20:35 - 22:30


Day 2 - Thursday, 9th May 2013
Time Speaker Title
09.00 - 12.10

SESSION 2 - Comparative epigenomics

Chairs: Jason Lieb and Denise Barlow
09:00 - 09:25

Oliver Rando, University of Massachusetts Medical School, USA

Fungal chromatin structure and function
09:25 - 09:40

Philipp Steffen, IMBA - Institute of Molecular Biotechnology, Austria

Retention of the Drosophila TrxG protein ASH1 on mitotic chromatin may act as bookmark for active gene expression states
09:40 - 09:55

Julia Zeitlinger, Stowers Institute for Medical Research, USA

Global recruitment of paused Pol II during the Drosophila maternal-to-zygotic transition
09:55 - 10:20

Henk Stunnenberg, Nijmegen Centre for Molecular Life Sciences, The Netherlands

The epigenome of groundstate mouse embryonic stem cells
10:20 - 10:50


ATC Foyer
10:50 - 11:15

Tony Kouzarides, Gurdon Institute, University of Cambridge, United Kingdom

Epigenetic pathways in transcription and cancer
11:15 - 11:30

Crisanto Gutierrez, Centro de Biologia Molecular Severo Ochoa, CSIC-UAM, Spain

Epigenomic landscapes of DNA replication origins in a live organism
11:30 - 11:45

Constance Alabert, BRIC, Copenhagen University, Denmark

Chromatin dynamics during DNA replication and new replication factors determined by Nascent Chromatin Capture (NCC) proteomics
11:45 - 12:10

Bas van Steensel, The Netherlands Cancer Institute, The Netherlands

Probing position effects in high throughput mode
12:10 - 13:30


EMBL Canteen
13:30 - 16:00

POSTER SESSION I (abstracts 53- 138)

Helix A
16.00 - 19.10

SESSION 3 - Balancing the Genome

Chairs: Asifa Akhtar and Craig Peterson
16:00 - 16:25

Barbara Meyer, HHMI and University of California at Berkeley, USA

Repressing chromosomes via molecular machines
16:25 - 16:40

Ibrahim Avsar Ilik, Max-Planck Institute of Immunobiology and Epigenetics, Germany

A tandem-stem RNA motif mediates X-chromosome dosage compensation in Drosophila
16:40 - 16:55

Peter B. Becker, Ludwig Maximilians Universität, Germany

A role for long, non-coding roX RNA for the biogenesis of the dosage compensation complex in Drosophila
16:55 - 17:20 Susan Strome, University of California, Santa Cruz, USA X-Chromosome regulation in the germline of C. elegans
17:20 - 17:50


ATC Foyer
17:50 - 18:15

Denise Barlow, CeMM Center for Molecular Medicine of the Austrian Academy of Sciences, Austria

Gene silencing by macro lncRNA transcriptional interference
18:15 - 18:30

Yehudit Bergman, The Hebrew University, Israel

Allelic plasticity and commitment in the hematopoietic system
18:30 - 18:45

Jop Kind, Netherlands Cancer Institute, The Netherlands

Nuclear lamina – genome interactions in single cells
18:45 - 19:10

Jason Lieb, The University of North Carolina at Chapel Hill, USA

The nuclear envelope: A nexus for gene regulation
19:10 - 20:30


EMBL Canteen
20:30 - 21:30


ATC Foyer and ATC Rooftop Lounge (top of Helix A)
Day 3 - Friday, 10th May 2013
Time Speaker Title
09.00 - 12.10

SESSION 4 - Chromatin structure and organization in development

Chairs: Barbara Meyer and Ali Shilatifard
09:00 - 09:25

Anne Kathrin Voss, Walter and Eliza Hall Institute of Medical Research, Australia

MYST lysine acetyltransferases in stem cell function and histone acetylation
09:25 - 09:50

Christine Disteche, University of Washington, USA

Upregulation of the mammalian X chromosome is associated with enhanced transcription initiation,MOF-mediated H4K16 acetylation, and longer RNA half-life
09:50 - 10:05

Simao Teixeira da Rocha, Curie Institute, France

Xist RNA dependent JARID2 recruitment is crucial for efficient PRC2 targeting to the inactive X-chromosome
10:05 - 10:30

Asifa Akhtar, Max Planck Immunobiology and Epigenetics, Germany

Epigenetic regulation by MSL proteins
10:30 - 11:00


ATC Foyer
11:00 - 11:15

Marc Timmers, University Medical Center Utrecht, The Netherlands

Nucleosomal DNA binding drives the recognition of H3K36 methylated nucleosomes by PWWP domains
11:15 - 11:30

Katalin Fejes Toth, California Institute of Technology, USA

Small-RNA guided epigenetic regulation of transposon expression in the Drosophila germline
11:30 - 11:45

Ashby Morrison, Stanford University, USA

Dynamic regulation of the INO80 chromatin-remodeling complex in global transcription
11:45 - 12:00

Manolis Papamichos-Chronakis, Curie Institute, France

Integration of the INO80 remodeling complex in the ubiquitin degradation pathway is essential for genome stability
12:10 - 13:30


ATC Foyer
13:30 - 16.00

POSTER SESSION II (abstracts 139- 224 )

Helix A & B
16:00 - 17:00 SESSION 5 - Keynote lecture:  

Peter A. Jones, USC Norris Comprehensive Cancer Center, USA

Cancer Epigenetics and Epigenetics: Two Sides of the Same Coin?


Day 4 - Saturday, 11th May 2013
Time Speaker Title
09.00 - 12.05

SESSION 6 - Chromatin dynamics and inheritance

Chairs: Wolf Reik and Maria Elena Torres-Padilla
09:00 - 09:25

Geneviève Almouzni, CNRS/Curie Institute, France

CenH3 misregulation impacts histone deposition dynamics in human cells
09:25 - 09:50

David M. Gilbert, Florida State University, USA

The Replication Domain Model: regulating replicon firing in the context of large scale chromatin architecture
09:50 - 10:15

Craig Peterson, University of Massachusetts Medical School, USA

A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme
10:15 - 10:30

 Robert Schneider, IGBMC, France

A causative function of histone modifications in regulation of chromatin dynamics and transcription
10:30 - 11:00


ATC Foyer
11:00 - 11:25

Ali Shilatifard, Stowers Institute for Medical Research, USA

Chromosomal translocations and transcriptional elongation control in epigenetics and cancer
11:25 - 11:50

Jane Mellor, University of Oxford, United Kingdom

Antisense transcription resets the epigenetic status of genes via dynamic, acetylated chromatin
11:50 - 12:05

David Tremethick, The Australian National University, Australia

Different strategies utilizing histone variants to create an open and dynamic chromatin structure at the transcription start site and at exon-intron boundaries
12:05 - 13:30


EMBL Canteen
13:30 - 16:00

POSTER SESSION III (abstracts 225- 308)

Helix B
16.00 - 19.25

SESSION 7- Chromatin plasticity

Chairs: Geneviève Almouzni and Bas van Steensel
16:00 - 16:25

Giacomo Cavalli, Centre National de la Recherche Scientifique, France

Polycomb proteins and chromosome organization in fly development
16:25 - 16:50

Jürg Müller, Max Planck Institute of Biochemistry, Germany

Targeting and function of histone modifications
16:50 - 17:05

Raphaël Margueron, Curie Institute/INSERM U934/CNRS UMR3215, France

A new feedback loop regulates polycomb complex PRC2
17:05 - 17:35


ATC Foyer
17:35 - 18:00

Kevin Struhl, Harvard Medical School, USA

Determinants of nucleosome positioning
18:00 - 18:15

Lukasz M. Boryn, Research Institute of Molecular Pathology (IMP), Austria

Direct and quantitative identification of enhancers in flies and human by STARR-seq
18:15 - 18:30

Yad Ghavi-Helm, European Molecular Biology Laboratory, Germany

A temporal view of three-dimensional enhancer interactions during embryonic development
18:30 - 18:45

Aleksandra Pekowska, European Molecular Biology Laboratory, Germany

Dynamic changes of the 3D chromatin interactome during cell differentiation
18:45 - 19:00 Myriam Ruault, Curie Institute, France Sir3 mediates long-range chromosomal interactions in budding yeast
19:00 - 19:25 Peter Fraser, Babraham Institute, United Kingdom The 3D path of DNA in chromosomes: the rise of active chromatin
19:25 - 19:30

Poster prize announcements

19:30 - 01:00


EMBL Canteen and ATC Foyer
Day 5 - Sunday, 12th May 2013
Time Speaker Title
09.00 - 12.00

SESSION 8 - Nuclear Reprogramming

Chairs: Yehudit Bergman and Giacomo Cavalli
09:00 - 09:25

Wolf Reik, Babraham Institute, United Kingdom

Epigenetic reprogramming in mammalian development
09:25 - 09:50

Amanda Fisher, MRC Clinical Sciences Centre, United Kingdom

Epigenetic reprogramming of somatic cells towards pluripotency
09:50 - 10:05

Poster Prize short talk 1

10:05 - 10:35


ATC Foyer
10:35 - 10:50

 Poster Prize short talk 2

10:50 - 11:15 

Maria Elena Torres Padilla, Institute of Genetics and Molecular and Cellular Biology, France

Epigenetic mechanisms of cell plasticity
11:15 - 11:40

Anton Wutz, Swiss Federal Institute of Technology, Switzerland

Gene dosage in mammals: Characterization of haploid embryonic stem cells
11:40 - 12:00

Concluding remarks