Bottom - Index of papers - Previous - Next - Previous - Next - Paper in HTML - Abstract - CUBIC
| Title: | 3rd Generation Prediction Of Secondary |
| Author: | Burkhard Rost & Chris Sander |
| Quote: | in: Webster D. M. (ed.): 'Predicting protein structure'. Humana Press, 1998, in press. (1998) |
We still cannot predict protein structure from sequence, in general.
But, we can do much better in predicting simplified aspects of
structure. Particularly, the field of secondary structure has
been revived by a break-through that has been achieved by a combination
of elaborated algorithms and evolutionary information available
in ever growing data bases. Some of the new, third generation
methods for secondary structure prediction are clearly superior
to previous methods: b-strands are
predicted more accurately; predicted segments look like those
observed; and the overall accuracy is about ten percentage points
higher than for methods from previous generations. Performance
can be improved even further by using these methods in an 'expert'
rather than in an 'automatic' mode.
Top -
Index of papers -
Previous -
Next -
Paper in HTML -
Abstract -
CUBIC