Domains within Homo sapiens protein PAX6_HUMAN (P26367)
Paired box protein Pax-6
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Transmembrane segments as predicted by the TMHMM2 program (
), coiled coil regions determined by the Coils2 program (
), segments of low compositional complexity determined by the SEG program (
).
Signal peptides determined by the SignalP program (
). Intron positions are indicated with vertical lines showing the intron phase and exact position in AA.
| Additional information |
|---|
| Display other IDs, orthology and alternative splicing data for this sequence. |
| Domain architecture analysis |
| This domain architecture was probably invented with the emergence of Metazoa. |
| Display all proteins with similar domain organisation. |
| Display all proteins with similar domain composition. |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Unstructured regions > Low complexity. In either case, features not shown in the above diagram are marked as 'overlap' in the second table below.
Confidently predicted domains, repeats, motifs and features:
| Name | Begin | End | E-value |
|---|---|---|---|
| PAX | 4 | 128 | 6.11e-92 |
| low complexity | 174 | 185 | - |
| HOX | 210 | 272 | 4.93e-26 |
| low complexity | 281 | 294 | - |
| low complexity | 387 | 395 | - |
| low complexity | 398 | 412 | - |
These features and domains are not shown in the diagram, either because their scores are less significant than the required threshold, or because they overlap with some other source of annotation:
| Name | Begin | End | E-value | Reason |
|---|---|---|---|---|
| Pfam:PAX | 4 | 128 | 2.00e-86 | overlap |
| low complexity | 203 | 212 | - | overlap |
| coiled coil | 208 | 232 | - | overlap |
| Pfam:Homeobox | 211 | 267 | 5.70e-30 | overlap |





