Domains within Homo sapiens protein PAX6_HUMAN (P26367)

Paired box protein Pax-6

Size
BubblogramPAX: 4 to 128Unknown region: 129 to 173low complexity region: 174 to 185Unknown region: 186 to 209HOX: 210 to 272Unknown region: 273 to 280low complexity region: 281 to 294Unknown region: 295 to 386low complexity region: 387 to 395low complexity region: 398 to 412Unknown: 413 to 422
Loading domain annotation...

Mouse over domain / undefined region for more info; click on it to go to detailed annotation; right-click to save whole protein as PNG image
Transmembrane segments as predicted by the TMHMM2 program ( TRANS ), coiled coil regions determined by the Coils2 program ( COIL ), segments of low compositional complexity determined by the SEG program ( SEG ). Signal peptides determined by the SignalP program ( SIGNAL ). Intron positions are indicated with vertical lines showing the intron phase and exact position in AA.

Additional information
Display other IDs, orthology and alternative splicing data for this sequence.
Domain architecture analysis
This domain architecture was probably invented with the emergence of Metazoa.
Display all proteins with similar domain organisation.
Display all proteins with similar domain composition.

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Unstructured regions > Low complexity. In either case, features not shown in the above diagram are marked as 'overlap' in the second table below.

Confidently predicted domains, repeats, motifs and features:

NameBeginEndE-value
PAX41286.11e-92
low complexity174185-
HOX2102724.93e-26
low complexity281294-
low complexity387395-
low complexity398412-

These features and domains are not shown in the diagram, either because their scores are less significant than the required threshold, or because they overlap with some other source of annotation:

NameBeginEndE-valueReason
Pfam:PAX41282.00e-86overlap
low complexity203212-overlap
coiled coil208232-overlap
Pfam:Homeobox2112675.70e-30overlap

Run BLAST with part of submitted sequence:
Start: End: