>gi|118099456|ref|XP_425326.2| PREDICTED: similar to Prostaglandin G/H synthase 1 precursor (Cyclooxygenase-1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) [Gallus gallus]
MEGLQSGAGGRSSVSHTCGHPAGFLLGVEVAVARQDTLTAPWLGRAALPHPTALLGSSKVPNAVAPRVDG
DLSSLSAVNPCCYYPCQHQGVCVRVGLEGYECDCTRTGYFGANCTSPELWTRLRDLLKPSPTFYHFVLTH
FRWFWDIINSTFIRDTLMRLVLTVRANLIPSPPTFNSQYGYISWEAYANVSYYTRILPPVPEECPTPMGT
KGKQQLPDAQLLAQRFLLRHKFEADPRGTNLMFAFFAQHFTHQFFKTSGKMGRGFTKALGHGVDLGHLYG
DNLQRQHQLRLFQDGKLKFQVVNGEVYPPSVTEVPVHMVYPPAIPKEKQLAMGQEVFGLLPGLCMYATLW
LREHNRVCDILKQEHPTWGDEQLFQTARLILIGETIKIVIEDYVQHLSGYFLNLKFDPELLFEQQFQYRN
RIAVEFNQLYHWHALMPDSFTIQGQEYSYEQFLYNTSMLMDYGVEALAESFSMQTAGRIGGGQNINANVL
GVAVGVIEESRQLRLQPFNEYRKRFGLKPYTSFQELTGEEDKAAELEELYGDIDALEFYPGLLLEKPQPN
GIFGESMVEIGAPFSLKGLLGNPICSPEYWKPSTFGGATGFEIVKTASLEKLVCLNVKKCPYVAFHVPDA
AAAGETDSGHAGGASSTEL

>gi|213626869|gb|AAI70301.1| Cyclooxygenase 1 [Xenopus laevis]
MAGLCLTMLFMIVTSSYSLEVSTKVNPCCYYPCQHKGVCVRFEMEEYQCDCTRTGYYGTNCTIPEWWTKF
RELIRPSPAFYHYILTRFKWFWDIINSTFIRDFIVRLVLTVRSNLIPSPPTYNSEYGYISWEAYSNVSYF
TRVLPPVPHDCPTPMGTKGKKELPDATFLVETFLKREKFIPDPQGTNLLFAFFAQHFTHQFFKTYGRMGR
GFIKGFGHGVDLSHIYGDSLERQHILRLFKDGKLKYQIINGETYPPTVVEAPVHMIYPENVPKEKQFAVG
QEVFGLLPGLMMYATLWLREHNRVCDVLKKEHPTWDDEQLFQTTRLILIGETIKIVIEDYVQHLSGYYLK
LKFDPELLFGVQFQYRNRIAVEFNQLYHWHPLMPEKFKIIEDEFGYSSFIYNTSIILDYGVEALVESFTK
QIAGKIGGGKNHPPSLLKVAAGVIEESRNLRLQPFNEYRKRFGLKAYKSFRDLTGEEKMAAQLEEFYGDI
DALEFYVGLLLEKPNPNSIFGESMVEIGAPFSLKGLLGNPICSPEYWKPSTFGGETGFNIVKTASIQKLV
CLNVKTCPFVAFHVPDVLPTLKKSDEL

>gi|147906023|ref|NP_001091389.1| cyclooxygenase 1 [Xenopus laevis]
MAGLCLTMLFMIVTSSYSLEVSTKVNPCCYYPCQHKGVCVRFEMEEYQCDCTRTGYYGTNCTIPEWWTKF
RELIRPSPAFYHYILTRFKWFWDIINSTFIRDFIVRLVLTVRSNLIPSPPTYNSEYGYISWEAYSNVSYF
TRVLPPVPHDCPTPMGTKGKKELPDATFLVETFLKREKFIPDPQGTNLLFAFFAQHFTHQFFKTYGRMGR
GFIKGFGHGVDLSHIYGDSLERQQILRLFKDGKLKYQIINGETYPPTVVEAPVHMIYPENVPKEKQFAVG
QEVFGLLPGLMMYATLWLREHNRVCDVLKKEHPTWDDEQLFQTTRLILIGETIKIVIEDYVQHLSGYYLK
LKFDPELLFGVQFQYRNRIAVEFNQLYHWHPLMPEKFKIIEDEFGYSSFIYNTSIILDYGVEALVESFTK
QIAGKIGGGKNHPPSLLKVAAGVIEESRNLRLQPFNEYRKRFGLKAYKSFRDLTGEEKMAAQLEEFYGDI
DALEFYVGLLLEKPNPNSIFGESMVEIGAPFPLKGLLGNPICSPEYWKPSTFGGETGFNIVKTASIQKLV
CLNVKTCPFVAFHVPDVLPTLKKSDEL

>gi|197734856|gb|ACH73265.1| cyclooxygenase-1b [Fundulus heteroclitus]
MRASVLGSVCALLVLLREPGCQGDEVTTSTVNPCCYLPCKHWSVCVRYGEDKYECDCTHTGYYGENCSIP
ELWTRVRQFLKPSPDVVHYILTHFHWLWDIINNTFLRNVLMRLVITARSNLIPSPPTFNSKYNYLSWESY
YNLSYYTRILPPVPEDCPTPLGVKGRNGLPDPQVLFERLLKRRTFRPDPQGSNIMFAFFAQHFTHQFFKT
YNRMGLGFTKALSHGVDAGHIYGDSLERQHLLRLFRDGKLKYQLIDGEVYPPSVTDAPVRMSYPPGIPVE
KQMAIGQEVFGLLPGLSLYATLWLREHNRVCDILKAEHPTWDDEQLFQTTRLIIIGETIRIVIEEYVQHL
SGYLLQLKFDPTLLFNSNFQYGNRIALEFSQLYHWHPLMPDSFHISGDELSYSQFLFNTSVLTHYGVEKL
VDAFSRQAAGQIGGGHNINAVITKVIVGTIEESRQLRIQPFNEYRKRFNLEPYTSFRDFTDSEEIASTLE
ELYGDIDTLEFYPGLLLEKTRPGAIFGESMVEMGAPFSLKGLLGNPICSPQYWKPSTFGGKVGFDIVNSA
SLKKLVCLNSRTCPYVAFSVPAEEEPGRNDGKERSSEL

>gi|139005800|dbj|BAF52621.1| cyclooxygenase-1 [Micropogonias undulatus]
MRSSVLGSVWALLLLLREPACRGDEVTSSTVNPCCYLPCQHWGVCVRYGEDKYECDCTRTGYFGENCTVP
EFWTRVRQFLKPSPDVVHYILTHFRWLWDIVNYTYLRDVLMRLVLTARSTLIPSPPTYNSKYSYLSWESY
YNLSYYTRLLPPVPKDCPTPLGVKGKAGLPDPELLVERLLKRRTFRLDPQGSNLMFAFFAQHFTHQFFKT
YNRMGLGYTKALAHGVDAGHIYGDSLKRQLQLRLHKDGKLKYQLIDGEIYPPSIADAPVRMNYPPGIPPE
KQFAIGQEVFGLLPGLGMYATLWLREHNRVCDILKAAHPTWDDDQLFQTSRLIIIGETIKIVIEEYVQHL
SGYLLQLKFDPTLLFNSNFQYGNRIALEFSQLYHWHPLMPDYFIINGDEVSYTQFLFNTSVLTHYGIDKL
VDAFSRQNAGQIGGGHNINPVVTKVAVGAIKESRQLRMQPFNEYRKRFNLKPYTSFREFTDNEEIARELE
EFYGDIDSVEFYPGLMLEKTRSGAIFGESMVEMGAPFSLKGLLGNPICSPEYWKPSTFGGKVGFDIVNSA
TLKKLVCLNSKRCPYVAFRVPTEEQLQRESDDSKKRPDEL

>gi|197734871|gb|ACH73272.1| cyclooxygenase-1b [Myoxocephalus octodecemspinosus]
MRSPVLGPVCALLLLLREPACRGDEVTSDTVNPCCYFPCQHWGVCVRYGEDKYECDCTRTGYTGGNCTVP
EFWSRVHQFLKPSPEVLHYILTHFNWLWDIINHTFLRDVLMRMVLTVRSNLIPSPPTYNSKYDYLSWESY
YNLSYYTRILPPVPKDCPTPLGVKGKAGLPDPELLVERLLKRRTFRPDPQGSNLMFAFFAQHFTHQFFKT
YNRMGVGFTKALAHGVDAGHVYGDNLQRQLKLRLHKDGKLKYQLVDGQIYPPSVVDAPVKMSYPPGVPPE
AQMAICQEVYGLLPGLGMFATLWLREHNRVCDILKAEHPTWDDEQLFQTARFVIIGETIKIVIEEYVQQL
SGYLLQLKFDPALLFNSNFQYGNRIALEFSQLYHWHPLMPESFLINGDELPYKRFLFNNTVLTHYGIENL
VTAFSRQVAGQIGGGFNINAAVTKVSVLTIKESRKLRMQPFNEYRKRFNLKPYTSFREFTDNEEIARELE
EFYGDVDALEFYPGLLLERTREGSIFGESMVEMGAPFSLKGLLGNPICSPVYWKPSTFGGKVGFDIVNSA
TLKKLVCLNTRTCSYVAFRVPTEEQLKTGNDDSKTRTDEL

>gi|6502967|gb|AAF14529.1|AF158374_1 prostaglandin endoperoxide synthase-1; cyclooxygenase-1 [Salvelinus fontinalis]
MRGLVVCVWACILLQRLPTCRGEEVKDVSTNVVNPCCYYPCQNWALCVRFGIDRYECDCTRTGFYGQNCT
IPEFWTRIHQQLKPSPDVVHYILTHFHWLWNLINRTFMRDWLMRMVLTVRSNLIPSPPTFNSKYGYLSWE
SYSNVSYYTRILPPVPEDCPTPMGTKGKSVLPDPKLVVEKFLLRRQFRPDPKGTNLMFAFFAQHFTHQFF
KTRNSMGLGFTSALGHGVDAGNVYGDNLVRQLNLRLLKDGKMKYQVVKGEVYPPTVAEAPVNMRYPQGTP
VGQRMAIGQEVFGLLPGLTMYATLWLREHNRVCDILKAEHPTWGDEQLFQTARLIVIGETIRIVIEEYVQ
HLSGYLLDLKFDPVLLFKSTFQYRNRIAVEFNQLYHWHPLMPDSFHIDGDVVSYSQFIFNTSIVTHYGVE
KLVDAFSRQYAGQIGGGRNIHPVVTKVAEGVIEESRTLRLQPFNEYRKRFNLKPYTSFSDFTGEEEMARE
LEELYGDIDALEFYPALMLEKTRPNAIFGESMVEMGAPFSLKGLLGNPICSPEYWKPSTFGGQTGFDIVN
SASLERLVCLNTNWCPYVAFNVPPAGQEPPPRKQSTEL

>gi|185133942|ref|NP_001117833.1| cyclooxygenase-1 [Oncorhynchus mykiss]
MSAAYIIFALLYWEDAPAEGAYAVNLTMRECVVWVWACILLQRLPTCRGEEVEDASTVVNPCCYYPCQNW
GVCVRFGIDRYECDCTRTGFYGQNCTIPEFWTRVHQQLKPSPDVVHYILTHFHWLWNLINRTFMRDWLMR
VVLTVRSNLIPSPPTFNSKYGYLSWESYSNVSYYTRILPPVPEDCPTPMGTKGKSVLPDPKLVVEKFLLR
RQFRRDPRGTNLMFAFFAQHFTHQFFKTRNSMGLGFTRALGHGVDAGNVYGDNLVRQLNLRLLKDGKMKY
QVVKGEVYPPTVAEAAVNMRYPQETPVGQRMAIGQEVFGLLPGLTMYATLWLREHNRVCDILKAEHPTWG
DEQLFQTARLIVIGETIRIVIEEYVQHLSGYLLDLKFDPVLLFKSTFQYRNRIAVEFKQLYHWHPLMPDS
FHIDGDEVPYSQFIFNTSIVTHYGVEKLVDAFSRQCAGQIGGGRNIHPVVTNVAEGVIEESRTLRLQPFN
EYRKRFNLKPYTSFSDFTGEEEMARELEELYGDIDALEFYPAIMLEKTRPNAIFGESMVEMGAPFSLKGL
LGNPICSPEYWKPSTFGGQTGFDIVNSASLERLVCLNTNWCPYVAFNVPPAGQEEPPRKQSTEL

>gi|213513266|ref|NP_001133846.1| Prostaglandin G/H synthase 1 [Salmo salar]
MRECVVCVWACILLQRLPTCPGEEGKDASTNVVNPCCYYPCQNWGVCVRFGIDRNECDCTRTGFYGQNCT
IPEFWTRIHQQLKPSPDVVHYILTHFHWLWNLINRTFMRDWLMRVVLTVRSNLIPSPPTFNSKYGYLSWE
SYSNVSYYTRILPPVPEDCPTPMGTKGKSVLPDPKLVVEKFLLRRQFRRDPKGTNLMFAFFAQHFTHQFF
KTRNSMGLGFTRALGHGVDAGNVYGDNLERQLSLRLLKDGKMKYQVVKGEVYPPTVAEAPVNMRYPQGTP
VGHRMAIGQEVFGLLPGLTMYATLWLREHNRVCDILKAEHPTWGDEQLFQTARLIVIGETIRIVIEEYVQ
HLSGYLLDLKFDPVLLFKSTFQYRNRIAVEFKQLYHWHPLMPDSFHIDGDVVPYSQFMFNTSIVTHYGVE
KLVDAFSRQYAGQIGGGRNIHPVVTNVAEGVIEESRTLRLQPFNEYRKRFNLKPYTSFSDFTGEEEIARE
LEELYGDIDALEFYPAIMLEKTRPNAIFGESMVEMGAPFSLKGLLGNPICSPEYWKPSTFGGQTGFDIVN
SASLERLVCLNTNWCPYVAFNVPPAGQEEPPRKQSTEL

>gi|24119249|ref|NP_705942.1| prostaglandin-endoperoxide synthase 1 [Danio rerio]
MRECNFLLKWTVILLLSVSFCAGEESPTSSNTANPCCYYPCQNQGICVRYGLERYECDCTRTGYYGENCT
IPELWTRVYRLLKPSPNVVHYILTHFDWLWDLINRSFLRDWLMRKVLTVRANLIPSPPTYNSRYDYLNWE
AYSNITYYTRILPPVPNDCPTPMGTKGKIKLPDPKLLVEKFMLRRNFRLDPQGTNLMFAFFAQHFTHQFF
KTHNRVGLGFTKGLGHGVDAGHIYGDSLDRQLELRLHKDGKLKYQVLNGDIYPPTVLHAQVKMSYPPSVP
PEQQLAIGQEVFGLLPGLGMYATLWLREHNRVCEILKQEHPTWGDEQLFQTARLIIIGETIRIVIEEYVQ
HLSGYRLKLHFDPTLLFNSQFQYQNRISVEFNQLYHWHPLMPDSFYIDGDHIQYSKFIFNTSILTHYGLE
KLVEAFSIQPAGQIGGGHNIHPVVSGVAERVIVESRELRLQPFNEYRKRFNLKPYTSFAELTGEQEMSKE
LEELYGHIDAMEFYPALLLEKTRPGAVFGESMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGKTGFDIVN
SATLKKLVCLNTKWCPYVSFHTPPSDYKPQRTSHGEL

>gi|94574383|gb|AAI16576.1| Ptgs1 protein [Danio rerio]
MRECNFLLKWTVILLLSVSFCAGEESPTSSNTANPCCYYPCQNQGICVRYGLERYECDCTRTGYYGENCT
IPELWTRVYRLLKPSPNVVHYILTHFDWLWDLINRSFLRDWLMRKVLTVRANLIPSPPTYNSRYDYLNWE
AYSNITYYTRILPPVPNDCPTPMGTKGKIKLPDPKLLVEKFMLRRNFRLDPQGTNLMFAFFAQHFTHQFF
KTHNRVGLGFTKGLGHGVDAGHIYGDSLDRQLELRLHKDGKLKYQVLNGDIYPPTVLHAQVKMSYPPSVP
PEQQLAIGQEVFGLLPGLGMYATLWLREHNRVCEILKQEHPTWGDEQLFQTARLIIIGETIRIVIEEYVQ
HLSGYRLKLHFDPTLLFNSQFQYQNRISVEFNQLYHWHPLMPDSFYIDGDLIQYSKFIFNTSILTHYGLE
KLVEAFSIQPAGQIGGGHNIHPVVSGVAERVIVESRELRLQPFNEYRKRFNLKPYTSFAELTGEQEMSNE
LEELYGHIDAMEFYPALLLEKTRPGAVFGESMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGKTGFDIVN
SATLKKLVCLNTKWCPYVSFHTPPSDYKPQRTSHGEL

>gi|47210129|emb|CAF95578.1| unnamed protein product [Tetraodon nigroviridis]
LVSDAFLSSPVNPCCYLPCQHWGVCVRYGLDQYQCDCTRTGYYGENCTVPEFWTRVRLLLRPSPDGAHYI
LTHFQWLWDIVNHTFLRDFLMRLVITVRSNLVPYPPTYNSKYGYLNWESMSNLSYYTRILPPVPEDCPTP
MGVKGKEELPDPELLVERLLRRRTFRPDPQGTNLMFAFFAQHFTHQFFKTYNRMGLGFTKALDHGVGAGH
IYGDTLDRQLQLRLHKDGKLKFQVLEGEVYPPSGMDVPIRMNYPSRIPPEKTFAIGQEMFGIIPGLTMYA
TLWLREHNRVCDILKAEHPTWDDEQLFQTSRLIIIGEKGWTAVFLPYGTSCLTAALPLAGETIKIVIEEY
VQQLSGYLLDLKFDPAMLFNTQFQYGNRIALEFTQLYHWHPLMPDRFLIDGDEVLYEQFLYNTSVLIHYG
VDKMVEAFSLQAAGQIGGGHNVPAMLTDVAVRTIKESRQLRLQPFNEYRKRFNLQPYTSFREFTDNEEIA
RELEEFYGDIDALEYYPGLMLEKTRPGAIFGESMVEMGAPYSLKGLLGNPICSPEYWKPSTFGGKVGFDI
VNSATLKDLVCYNTKTCPFVAFRVPKEAQ

>gi|17226311|gb|AAL37727.1|AF420317_1 cyclooxygenase [Squalus acanthias]
MEAARIILLLLPLCFLKMADTTAINPCCYYPCQNKGICVNVGKEGYECDCTRTGYYGVNCTFPFSWSRVH
KFLKPSPSSMHHVLTHYKWLWYIINNISFFSDTLMRLVLTVRANIIPSPPTYNSDYTYVSWEGYSNISYL
TRLLPPVPKDCPTPTGTQGYKKLPDSEQLAEEFLLRRKFIPDPQGSNLMFAFFAQHFTHQFFRTDLDRGP
GFTKALGHGVDLTHIYGDSLERQHHLRLFKDGKLKYQVVNGEVFPPSVKEAPIQMKYPSTLPEEKRLAIG
HDTFGLIPGLMMYATIWLREHNRVCDILKEEHPVWSDEQLFQTTRLILIGETIKIVIEDYVQHLSGYNFR
MMFNPELLFTEHFQYSNRIAVEFDHLYHWHPLMPDSFIVKGQDFSYKDFLFNTDILLNLGVDALVESFSK
QIAGRIGGGRNIHQSLLHIAIATIEHGRLLRFQPYNEYRKKLGLTPYKSFQELTGEREVAARLEKLYGHI
DAMEFYPALLLEAPNKNSIFGESMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGKTGFDIVNTATFEKLI
CLNVKKCPYVGFHVPYNVDNDYEREKGKPSTEL

>gi|70887621|ref|NP_001020675.1| prostaglandin-endoperoxide synthase 2b [Danio rerio]
MKSSVLFIFLLLGFVVCTGANPCCSHPCQNRGVCTEMGSDAYECDCTRTGYYGQNCTTPEFLTWVKVSLK
PSPNTVHYILTHFKSLWNIINNVSFLRNGIMRYVLTSRAHLIDSPPTFNADYGYKSWEAYSNLSYYTRTL
PPVPRDCPTPMGVAGKKELPDVKMLAEKLLLRRKFIPDPQRTNLMFAFFAQHFTHQFFKSDMKKGPAFTT
ALNHGVDLAHIYGQNLDRQHKLRLFKDGKLRYQILDGEVYPPTVSEVQVDMHYPPHVPESRRFAVGHEAF
GLVPGLMMYATIWLREHNRVCDILKQEHPDWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYYFKLKFD
PELLFNERFQYQNRISSEFNTLYHWHPLMPDDFHIQDEVYNYQQFLFNTSILTDYGVNSLVESFNKQIAG
RVAGGRNVAPAVLRVAIKSIENSRQMRYQSINAYRKRFNMKPYRSFEEMTGEKEMAAELEEMYGDVDAVE
LYAGLLVEKPRSNAIFGETMVEMGAPYSLKGLMGNPICSPEYWKPSTFGGKVGFEIVNSASLQNLVCNNV
NGPCPMASFYVPNVKDSLPTTINASTSQSDRNVNPTVLLKERTSEL

>gi|139005693|dbj|BAF52620.1| cyclooxygenase-2 [Micropogonias undulatus]
MNKLTFAVFLLALGFLVCEAGNPCCAEPCQNKGVCTSLGAENYECDCTRTGYFGQNCTTPEFLTWLKITL
KPSPNTVHYLLTHFKGFWNIVNNISFLRDGIMTYVLTSRSHMIDSPPTFNADYSYKCWEAYSNLSYYTRT
LPPVPKDCPTPMGVVGKKELPDAKVLAEKLLVRRQFIPDPQGTSLMFAFFAQHFTHQFFKSDMKNGPAFT
LSKGHGVDLSHIYGDNLERQHKLRLFKDGKMKYQIVDGEVYPPTVQEVGVHMHYPPHVPDSHRFAVGHEA
FGLVPGLMMYATIWLREHNRVCDVLKEVHPDWDDERLFQTTRLILIGETIKIVIEDYVQHLSGYNFKLKF
DPQLLFNQRFQYQNRISSEFNTLYHWHPLMPDSFQIEEKDYSYKQFVFNTSVVTEHGISNLVESFSKQVA
GRVAGGRNVPGPILHVAIKSIEDSRKMRYQSLNAYRKRFSMKPYTSFEDMTGEKEMAAVLEEMYGHIDAV
ELYPGLLVEKPRSNAIFGETMVEMGAPYSFKGLMGNPICSPEYWKPSTFGGSVGFDIVNTASLQKLVCNN
VQGPCPVASFHVPDAPMTGSMIINSSTSHSRSSDINPTVILKERTTEL

>gi|50751211|ref|XP_422297.1| PREDICTED: prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) isoform 2 [Gallus gallus]
MLLPCALLAALLAAGHAANPCCSLPCQNRGVCMTTGFDRYECDCTRTGYYGENCTTPEFFTWLKLILKPT
PNTVHYILTHFKGVWNIINNISFLRDTIMRYVLTSRSHLIDSPPTYNSDYSYKSWEAYSNLSYYTRSLPP
VGHDCPTPMGVKGKKELPDSKLIVEKFLLRRKFIPDPQGTNVMFTFFAQHFTHQFFKTDHKKGPGFTKAY
GHGVDLNHIYGETLERQLKLRLRKDGKLKYQMIDGEMYPPTVKDTQAEMIYPPHVPEHLQFSVGQEVFGL
VPGLMMYATIWLREHNRVCDVLKQEHPEWDDEQLFQTTRLILIGETIKIVIEDYVQHLSGYHFKLKFDPE
LLFNQRFQYQNRIAAEFNTLYHWHPLLPDTFQIHNQEYTFQQFLYNNSIMLEHGLSHMVKSFSKQSAGRV
AGGKNVPAAVQKVAKASIDQSRQMRYQSLNEYRKRFMLKPFKSFEELTGEKEMAAELEELYGDIDAMELY
PGLLVEKPRPGAIFGETMVEIGAPFSLKGLMGNTICSPEYWKPSTFGGKVGFEIINTASLQKLICNNVKG
CPFTAFHVLNPEPTEATINVSTSNTAMEDINPTLLLKEQSAEL

>gi|47175549|gb|AAS21313.2| cyclooxygenase 2 [Fundulus heteroclitus]
MNRITFAVFLLALCFSFHKEVLGNACCSEPCQNRGVCTAMGSDSYECDCTRTGYRGQNCTTPEFLTWIKI
SLKPTPNTVHYILTHFKGFWNIINNISFLRDAIMKYVLTSRSHMIDSPPTYNADYGYKSWEAYSNLSYYT
RALPPVPEDCPTPMGVVGKKELPDVKVLAEKLLVRRRFIPDPQGTSLMFAFFAQHFTHQFFKSDMKNGPA
FTVAKGHGVDLGHIYGENLEKQHKLRLFKDGKLKYTMVNGEVYPPLVKDVGVEMHYPPHVPDSQRFAVGH
EAFGLVPGLLMYATIWLREHNRVCDVLKGVHPDWDDERLFQTTRLILIGETIKIVIEDYVQHLSGYHFKL
KFDPELLFNQRFQYQNRIASEFNTLYHWHPLMPDSFHIEEKDYSYKEFVFNTSVVTEHGINNLVDSFSKQ
IAGRVAGGRNVPGPIMYVAIKSIENSRKMRYQSLNAYRKRFSMKPYTSFEDLTGEKEMAAILEELYGDVD
AVELYPGLLVEKPRTNAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGTAGFDIVNTASLQRLVC
NNVRGPCPVASFYVPDVKETGSMTINSSTSHSRDSNINPTVILKERTSEL

>gi|71895727|ref|NP_001025697.1| prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) [Xenopus (Silurana) tropicalis]
MIVLPAAVFLSLLVFSQAANPCCSNPCQNRGVCMTVGHDRYECDCTRTGFYGENCTKPEFLSWLRLKLKP
APNTVHYILTHFKGLWNIVNNISFLRDAIMRYVLTSRSHLIDSPPTYNSHYGYKSWEAFSNLSYYTRTLP
PVERDCPTPMGVKGMKELPSAKLVVEKFLMRRKFIPDPQGSNVMFAFFAQHFTHQFFRTDMAKGAAFTKA
LGHGVDLNHIYGESLERQHKLRLMKGGKLKYQMISGEMYPPTVKTTGVDMVYPPHIPDHLQFAVGQEVFG
LVPGLMMYSTIWLREHNRVCDILSNEHPEWDDERIFQTARLILIGETIKIVIEDYVQHLSGYHFKLKFDP
ELLFNQKFQYQNRISAEFNTLYHWHPLLPDTFAISEKEYSYPQFLYNNSVMLNHGLTEMVESFSRQTAGR
VAGGRNFPAAITRVAVASIEHSREMRYQSLNEYRKRFMLKPFESFEELTGEKEMSAELEKLYGDIDAMEF
YPGLLVEQPRPGAIFGETMVEIGAPFSLKGLMGNPICSPEYWKPSTFGGSVGFDIVNSASLQKLICNNVR
DCPYTAFHVLKSKPSEKDFINASSDSTLENVKPSLILKEHASEL

>gi|185135435|ref|NP_001118139.1| prostaglandin G/H synthase 2b [Oncorhynchus mykiss]
MNRIISALLFLPLGIIFVCEGGNPCCSQPCMNRGVCTAMGSEDYECDCTRTGFYGHNCTQPEFFTWIKVS
LKPTPNTVHYLLTNYKGVWNIINSISFLRDAIMRYVLTSRSHLIDSPPTFNADYNYKSWEAYSNLSYYTR
TLPPLPKDCPTPMGVVGKIELPDAKMLAEKLLIRRKFIPDPQGSSLMFAFFAQHFTHQFFKSDQKMGPAF
TKAKGHGVDLGHIYGENLERQHKLRLFKDGKLKFQVLDGEVYPPTVKEVGADMHYPPHVPESHRFAVGHE
AFGLVPGLMMYATIWLREHNRVCDVLKEVHPDWDDDRLFQTSRLILIGETIKIVIEDYVQHLSGYNFKLK
FDPELLFKERFQYQNRISSEFNTLYHWHPLMPDAFHIQEQVYSYPQFVFNTSVVTTHGISNLVASFTKQI
AGRVAGGRNVPPAVMMVALKSIENSRQMRYQSLNAYRKRFSMKPYASFEDLTGEKEMAAELEEMYGHVDA
VELYPGLLVEKPRTNAIFGETMVEMGAPYSLKGLMGNPICSPEYWKPSTFGGSVGFDIINTASLQRLVCS
NVKGPCPVASFHVPDVEDNRSNTINSSTAQSGSNDVNPTVLLKEGTTEL

>gi|147903100|ref|NP_001086946.1| prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) [Xenopus laevis]
MIVLPAAVFLALLVFSQAANPCCSNPCQNQGVCMTVGFDRYECDCTRTGFYGENCTKPEFLSWLRLKLKP
TPNTVHYILSHFKGVWNIVNSMSFLRDAIMRYVLTSRSHLIDSPPTYNSHYTYKNWETYSNLSYYTRSLP
PVERDCPTPMGVKGLKELPSSKLVVEKFLMRRKFIPDPQGTNVMFAFFAQHFTHQFFKTDMAKGAAFTKA
LGHGVDLNHVYGESLERQHKLRLMKGGKLKYQMIDGDMYPPTVKSSGVDMAYPPHVPEHVQFAVGQEVFG
LVPGLMMYSTIWLREHNRVCDILAGEHPEWDDERIFQTARLILIGETIKIVIEDYVQHLSGYHFKLKFDP
QLLFNQRFQYQNRIAAEFNTLYHWHPLLPDTFAINEKEYSYPQFLYNNSVMIDHGLTQMVESFSRQSAGR
VAGGRNFPAAITRVAVASIEHSREMRYQSLNEYRKRFMLKPFETFEELTGEKEMSAELEKLYGDIDAMEL
YPGLLVEQPRPGAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGSVGFDIVNSASFQKLICNNVR
DCPYTAFHVLKNKPSGKDFINASSDSTLENVKPSLILKEHTSEL

>gi|197734860|gb|ACH73267.1| cyclooxygenase-2b [Myoxocephalus octodecemspinosus]
MYRFTFAVFLLALGVLVCEGGNPCCSEPCQNRGVCTALGTDNYECDCTRTGYHGHNCTTPEFLTWVKISL
KPSPNTVHYILTHFKGFWNIINSISFFRDAIMRYVLTSRSHLIDSPPTFNADYGYKSWEAYSNLSYYTRT
LPPVPEDCPTPMGVVGKKELPDAKLLAEKLFMRRQFIPDPQGTSLMFAFFAQHFTHQFFKSDMKKGPAFT
LATGHGVDLNHVYGGSMERQHKLRLRQDGKLKYQVLDGEVYPPTVKEVGADMHYPPHVPESHRFAVGHEA
FGLVPGLMMYATIWLREHNRVCDVLKEVHPDWDDERLFQTTRLILIGETIKIVIEDYVQHLSGYNFKLKF
DPELLFNQRFQYQNRIASEFNTLYHWHPLMPDSFHIEEKDYSYKEFVFNTSVVTEHGIGNLVESFTNQIA
GRVAGGRNVPGPIMYVAIKSIENSRKMRYQSLNAYRKRFSMKPYSSFEDMTGEKEMAAILEEFYGHVDAV
ELYPGLLVEKPRSNAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGSEGFNIVNTASLQRLVCNN
VQGPCPVASFSGPDVKDSGSMIINSSTSNSDINPTVILKERTTEL

>gi|5639926|gb|AAD45896.1|AF158373_1 prostaglandin endoperoxide synthase-2; cyclooxygenase-2 [Salvelinus fontinalis]
MNKVVCIILLLTVGLYFCEGVDPCCAQPCENRGLCNSKGFDNYECDCTRTGYYGKNCTTPEFLTWIKISL
KPAPNTVHYILTHYKGLWNVINKITFVRNAIMSYVLTSRSHLVDSPPTYNADYGYKSWEAYSNLSYYTRT
LPPLPKDCPTPMGTAGRAVLPDVKLVVEKVLLRKRFIPDPQGSNLMFAFFAQHFTHQFFKSDLKKGPAFT
KALGHGVDLNHVYGDSLERQHKLRLFKDGKLKYQVLNGEVYPPLVREVGAEMHYPPQVPEEHRFAVGHEH
FGLVPGLMMYATIWLREHNRVCDVLRQEHPEWDDERIFQTTRLILIGETIKIVIEDYVQHLSGYHFQLKF
DPELLFNQRFQYQNRIAAEFNTLYHWHPLMPDTFSIEDRAYTYPQFVFNNSLVTEHGITNLVESFTKQIA
GRVAGGRNLPPALVAVAAKALEHSRDMRYQSLNAYRKRFNMRAYTSFEDLTGETELAAELESLYGDVDAV
ELYPGLLVERPRPNAVFGETMVEMGAPYSLKGLLGNPICSPEYWMPSTFGGSVGFDIVNTASLERLVCSN
VKGSCPMVSFQVPDFLRAFESASVNTSEAHLRGMNPGVVFKERTLEL

>gi|185133473|ref|NP_001117820.1| cyclooxygenase-2 [Oncorhynchus mykiss]
MNRVICIILLLAVGLYFCEGVDPCCAQPCENRGLCNSKGFDNYECDCTRTGYYGKNCTTPEFLTWIKISL
KPAPNTIHYILTHYKGLWNVINKITFVRNAIMSYVLTPRSHLVDSPPTYNADYGYKSWEAYSNLFYYTRT
LPPLPKDCPTPMGTAGRAVLPDVKLVVEKVLLRKRFIPDPQGSNLMFAFFAQHFTHQFFKSDFMKGPAFT
KALGHGVDLNHVYGDTLERQHKLRLFKDGKLKYRVLNGEVYPPLVREVGAEMHYPPQVPEEHRFAVGHEH
FGLVPGLMMYATIWLREHNRVCDVLRQEHPEWDDERIFQTTRLILIGETIKIVIEDYVQHLSGYHFQLKF
DPELLFNQRFQYQNRIAAEFNTLYHWHPLMPETFSIEDRAYTYPQFVFNNSLVTEHGINNLVESFTKQIA
GRVAGGRNLPPALVGVAAKALEHSRDMRYQSLNAYRKRFNMRVYTSFEDLTGETELAAELESLYGDVDAV
ELYPGLLVERPRPNAVFGETMVEMGAPYSLKGLLGNPICSPEYWMPSTFGGSVGFDILNTASLERLVCNN
VKGSCPMVSFQVPDFLRAFESASVNTSEAHLSDMNPGVLFKERTSEL

>gi|118094249|ref|XP_001231379.1| PREDICTED: prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) isoform 1 [Gallus gallus]
MTTGFDRYECDCTRTGYYGENCTTPEFFTWLKLILKPTPNTVHYILTHFKGVWNIINNISFLRDTIMRYV
LTSRSHLIDSPPTYNSDYSYKSWEAYSNLSYYTRSLPPVGHDCPTPMGVKGKKELPDSKLIVEKFLLRRK
FIPDPQGTNVMFTFFAQHFTHQFFKTDHKKGPGFTKAYGHGVDLNHIYGETLERQLKLRLRKDGKLKYQM
IDGEMYPPTVKDTQAEMIYPPHVPEHLQFSVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDE
QLFQTTRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQRFQYQNRIAAEFNTLYHWHPLLPDTFQ
IHNQEYTFQQFLYNNSIMLEHGLSHMVKSFSKQSAGRVAGGKNVPAAVQKVAKASIDQSRQMRYQSLNEY
RKRFMLKPFKSFEELTGEKEMAAELEELYGDIDAMELYPGLLVEKPRPGAIFGETMVEIGAPFSLKGLMG
NTICSPEYWKPSTFGGKVGFEIINTASLQKLICNNVKGCPFTAFHVLNPEPTEATINVSTSNTAMEDINP
TLLLKEQSAEL

>gi|197734863|gb|ACH73268.1| cyclooxygenase-2 [Myxine glutinosa]
MTSEVFVVLCVAVVFAGAAAADDPCCGSPCENKGVCVSVGFEDYECDCTRTGYYGSNCTYPETWTWIVNM
LKPLPDTVHYFLTHFAPFWSLVNRAAFLRDRVMRHVLMSRAHMVSSPPTYNADYGYKSWEAYSNLSYFTR
LLPPVPQGCPTPMGRTGKKELPDAQKLXERFLLRRTFIPDPQGSNLLFAFFAQHFTHQFFKTDFKRGPGF
TKALGHGVDLSHIYGDTLDKQHKLRLHNNGKLKFQMIDGEVFPPLVSEAPVDMIYPPHVPEAARFAVGHE
AFGLVPGLMLYGTLWLREHNRVCDVLDVDHPEWDDERIFQTARLILIGETIKIVIEDYVQHLSGYHFKLK
FDPKLLFGQPFQYSNRISVEFNHLYHWHGLNPDAFRVGTQEYQYSQFLFNNTILLNHGVRGLLEAFNVQQ
AGRIGGGQNIHGALLHVATASIKHGRKMRFQSLNQYRKQFGLQPYQSFEQLTGETEMAADLAELYSDINA
MEFYLGLMVEKPRQGALFGETMVEAGAPFSLKGLMGNAICSPEYWKPSTFGGNRGFEIVNSASLRRLVCL
NLQGPCPDVAFHVPRDNQQDVVVNVTGSQGGSDGVTTTPHYVADQQSREL

>gi|24119251|ref|NP_705943.1| prostaglandin-endoperoxide synthase 2 [Danio rerio]
MNKLVCLVLLSSIWIFPGEGYDPCCAQPCQNQGVCLSKGADAYECDCTRTGYYGENCTTPELLTRIKSAL
KPRPNVVHHILTHYKSIWDIINSISYLRDGIMRYILLSRSHLVESPPTYNADYGYKSWEAYSNLSYYTRT
LAPLPQNCPTPDLPNAKQVVEQVLLRKQFIPDPQRSSLMFAFFAQHFSHQFFKSDFKKGPAFTKALGHGV
DLGHIYGETLEVQHKLRLFKDGKLKYQVVDGEVYPPLVKDVQVEMHYPPHIPEEQKFAVGHEAFGLVPGL
MMYATIWLREHNRVCDIMKQEHPDWDDERIFQTTRLILIGETIKIVIEDYVQHLSGYNFKLKFDPELIFS
ERFQYQNRIAAEFNTLYHWHPLLPDNFQIQDQIYGYHQFVFNNSIVTTHGIRNMVDSFTKQTAGRVSGGR
NLPPAVQGVAVKVLEQTRQMRYQSFNAYRRRFNMKPYSSFEEMTGDKDLAAQLKELYGHVDKVELYPGLL
VEKSRPNSVFGETMVEMGAPYSLKGLMGNAICSPEYWKPSTFGGKVGFDIVNSASLKKLVCLNISGPCPM
VSFQVPDVKFQSSENVNSSSVHSTVNNINPTVVLNERSSEL

>gi|38649358|gb|AAH63232.1| Prostaglandin-endoperoxide synthase 2a [Danio rerio]
MNKLVCLVLLSSIWIFPGEGYDPCCAQPCQNQGVCLSKGADAYECDCTRTGYYGENCTTPELLTRIKSAL
KPRPNVVHHILTHYKSIWDIINSISYLRDGIMRYILLSRSHLVESPPTYNADYGYKSWEAYSNLSYYTRT
LAPLPQNCPTPDLPNAKQVVEQVLLRKQFIPDPQRSSLMFAFFAQHFSHQFFKSDFKKGPAFTKALGHGV
DLGHIYGETLEVQHKLRLFKDGKLKYQVVDGEVYPPLVKDVQVEMHYPPHIPEEQKFAVGHEAFGLVPGL
IMYATIWLREHNRVCDIMKQEHPDWDDERIFQTTRLILIGETIKIVIEDYVQHLSGYNFKLKFDPELIFS
ERFQYQNRIAAEFNTLYHWHPLLPDNFQIQDQIYGYHQFVFNNSIVTTHGIRNMVDSFTKQTAGRVSGGR
NLPPAVQGVAVKVLEQTRQMRYQSFNAYRRRFNMKPYSSFEEMTGDKDLAAQLKELYGHVDKVELYPGLL
VEKSRPNSVFGETMVEMGAPYSLKGLMGNAICSPEYWKPSTFGGKVGFDIVNSASLKKLVCLNVSGPCPM
VSFQVPDVKFQSSENVNSSSVHSTVNNINPTVVLNERSSEL

>gi|48596662|emb|CAF74800.1| cyclo-oxygenase-2 [Dicentrarchus labrax]
MQLVLVLLLAASLIPTYLAQPCCSIPCQNRGACAGNGFDNYECDCTRTGYYGRNCTTPEFITQLKPLKPA
PNTAHYILTHSKGVWNVINLIPFVRQVIMVYVLTGRSPLIDSPPTYNVEYGYKSWEAYSNLSYYTRILPP
VARDCPTPIGVVGKIALPDSKTAVEKLLRKRFIPDPQGTNIMFAFFAQHFTHQFFKSDMKKGPAFTVAKG
HGVDLSHIYGDKLERQHKLRLFKDGKLKYQMVNGEMYPPTVKEVGAEMHYPPHVPEAHRFAVGHEAFGLV
PGLMMYATIWLREHNRVCDILQQEHPEWDDELSFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPEL
LFNSRFQYQNRIVEFNTLYHWHPLLPDTFLIGEEVYSYGQFVFNNSSAPEHGIKRLVSSFTNQIAGRVAG
GRNIPLALGPVATEVIDYSRDMRYQSLNVYRKRFELRPYSSFEDLTGEPEIAAELEPLYADADIVELYPA
LLVEKPRPTAPFGETMVELGAPYSLKGLMGNLICSPLYWKPSTFGGVVGFSILNTASLESLICNNVKGCP
IASFEVPDFTSYPAINVSDIEDINPTVLLKEKTSEL

>gi|197734858|gb|ACH73266.1| cyclooxygenase-1a [Fundulus heteroclitus]
NLSYYTRLLPPVPKDCPLPMGTKGKPVLPDIKEISERYFKRTEFRPDPQGTNLMFAFMAQHFTHQFFKTS
HKVDAGFTKALGHGVDASNIYGEELERQHQLRLHKDGKLKYQLINGEMYPPTVSEVPVHMVYPEGFPAEQ
RLAIGQEVFGLVPGLTVYATIWLREHNRVCDILKGEHPTWDDEQLFQTARLIIIGEIINIIIEEYVQHLS
GYYLKLKYDPSLLFGVRFQYTNRIALEFCYLYHWHPLMPDSFLIDGDELPYSQFLYNTSILMHYGVEKLV
DAFSRQPAGQIGGGRNIHQAVLRVAEMVIRDSRAARLQPFNQYRKRFNLKPYSSFYELTGDEEMARGLEE
LYGDIDALEFYPGLLLEKTRPSSIFGESMVEMGAPFSLKGLLGNPINSPEYWKPSTFGGETGFNIIKTST
LKKLVCLNTKWCPYVDFHVPRNEEERKPSTEL

>gi|219485386|ref|XP_002239720.1| hypothetical protein BRAFLDRAFT_129952 [Branchiostoma floridae]
MNGAIIAICLTLLPVLIAAENPCCSMPCQNMGVCMREGDSYSCDCTRTGYYGQNCDIPEFWTSIKVALKP
SKKTTHHLLTNYKWLWNIVNRIPFLSKFIMRAVYKIRSATVDSPPMYHTGHDYTSWDTYADRSYYTRALP
PVPPGCPTPMGTAGRKELPSPQYIAETFLARRRFIPDKRRTNVLFNFMAQHFTHQFFKTDFKKGAGRTWG
DHGVDLSHIYGETVERQHQLRSFTDGKLKFQRVEGEVYPPSLADAPVHMIYPPYVPEGKRFAIGHEFFGL
LPGLFVYSTVWLREHNRVCDVMKELHPDWDDERLFQTARLILTGETINIIINEYVQHLSGYNFDLFWDPE
LLFSDQFQYQNRIFVEFNHLYHWHPLMPDQFHINGSTYGMKDYLFNTDLVFKHGFGTTVDAMSRQIAGQI
GPKNIGPVNLKVAVETIKHERNLRMQGLNQYRKRFGIPPYKTFLELTGGDAEMADQLEEAYGDVDAVELY
VGLMVEQPAPGSVTSETIIEMGGPFSVKGLLSNPLCSPQWWKPSTFGGEAGFRMVKTATLKDLFCRNTAG
PCGLVSFAVPEDVQPTGLPEEQDASSQGKGASQNDADLVPVNGVLSSQDKHLHKEEKTSQDGSQDPETSS
KVTANEKPVAKNEKLPKNGVAQKKEFQNGSPKNGRASKNDVPKNEPAPKNGLPTAFPKNGAAPRTYVNRT
SCKQCDRIEL

>gi|47222192|emb|CAG11618.1| unnamed protein product [Tetraodon nigroviridis]
TGNPCCSEPCQNRGVCTPIGKDSYECDCTLTGYAGPNCTTPEFLTWVKVSLKPSPNTVHYLLTHFKGFWN
IVNNISFLRDAIMRYVLTSRSHLIESPPTFNADYDYKSWEAYSNLSYYTRTLPPVSKDCPTPMGVAGKKE
LPDSKVLAEKVLMRRQFIPDPQRTSLMFAFFAQHFTHQFFKTDSKKGPAFTAAQGHGVDLGHIYGGDLER
QHKLRLFKDGKLQHQVINGEVYPPTVKDVGVEMQYPPHIPESERFAVGHEAFGLVPGLMMYATIWLREHN
RVCDVLKEVHPDWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFKERFQYQNRIASE
FNTLYHWHPLMPDSFHIEEKEYSYKEFVFNNSVVTRHGISHLVESFTKQLAGRVAGGRNVPKSLLYVSIK
SIENSRQMRYQSLNAYRKRFSMKPYSSFEEMTGGTE

>gi|219485392|ref|XP_002239723.1| hypothetical protein BRAFLDRAFT_285765 [Branchiostoma floridae]
MPCQNMGVCMTEGDSYSCDCTRTGYYGQNCDIPEFWTSIKVALKPSKKTTHHLLTNYKWLWNIVNRIPFL
SNFIMRAVYKIRSATVDSPPMYHTGHDYTSWDTYADRSYYTRALPPVPPGCPTPMGTAGRKELPSPQYIA
ETFLARRRFIPDKRRTNVLFNFMAQHFTHQFFKTDFKKGAGRTWGDHGVDLSHIYGETVERQHQLRSFTD
GKLKFQRVEGEVYPPSLADAPVHMIYPPYVPEGKRFAIGHEFFGLLPGLFVYSTVWLREHNRVCDVMKEL
HPDWDDERLFQTARLILTGETINIIINEYVQHLSGYNFDLFWDPELLFSDQFQYQNRIFVEFNHLYHWHP
LMPDQFHINGSTYGMKEYLFNTDLVFKHGFGTTVDAMSRQIAGQIGPKNIGPVNLKVAVETIKHERNLRM
QGLNQYRKRFGIPPYKTFLELTGGDAEMADQLEEAYGDVDAVELYVGLMVEQPAPGSVTSETIIEMGGPF
SVKGLLSNPLCSPQWWKPSTFGGEAGFRMVKTATLKDLFCRNTAGPCGLVSFAVP

>gi|219430282|ref|XP_002212929.1| hypothetical protein BRAFLDRAFT_75314 [Branchiostoma floridae]
MPRTVPSVPMLFSTFVCSDNLCCSFPCQNMGVCMREGDGYTCDCTGTGYYGQNCQTAEFWTMLKTALRPS
DQTIDHLTKNYKWLWHIINNTQALRNFLMRLFSKLYVDKVDSPPLYHTGHDYTTWDTYSARSYYTRALPP
VPKDCPTPMGTKGHKELPSPEYVAETSLGAQNVPPGHETTHQHALRLHGAALHSSVLQNRLQEGTWSHLE
RPCGKFLFVDMSHVYGETVERQRQLRSFQDGKLKYQLVNGEAFPPSLQDASVHMIYPPDVPEEKRFALGH
EFFGLLPGLFVWATVWLREHNRVCDVMKDLHPDWDDERLFQTARLILIGETINIVIGEYVQHLAGKNFQL
FWDPELLFEEQLQYQNSIFVEFNHLYHWHVLMPDQFHINGTMYDMEEYLYNNDIVLKHGLNTTVDAMSRQ
IAGRVAVETIKHERELRMQPLNQYRKRFGMPPYRTFLELTAGDTEMAAQLEEAYGDIDAVELYVGWAIEN
PMPGSVHSETIVRMGSTFSFKGMLANPICSPGWWKPSTFGGEVGFNLLKTTTLKDLFCRNMNGPCGLVSF
TVPEDVEPTGLTEDVESVGVPRKEGISRDKQTSQNQEL

>gi|198401184|gb|ACH87388.1| cyclooxygenase-2 [Oplegnathus fasciatus]
THQFFKSDMKKGPAFTVAKGHGVDLNHIYGDSLERQHKLRLLKDGKLKYQILDGEVYPPTVKEVGVDMHY
PPHVPDSHRFAVGHEAFGLVPGLMMYATIWLREHNRACDVLKEVHPDWDDERLFQTSRLILIGETIKIVI
EDYVQHLSGYHFKLKFDPELLFNQRFQYQNRIASEFNTLYHWHPLMPDSFHVEEQDYSYKQFVFNTSVVT
EHGISNLVESFTNQIAGRVAGGRNVPGPIMYVAIKSIENSRQMRYQSLNAYRKRFSMKPYSSFEDMTGEK
EMAAVLEEMYGHIDAVELYPGLLVEKPRPNAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGSVG
FDIVNTASLQRLVCNNVRGPCPVASFHVPDVKDTGSMIINSSTSHSRSSDINPTVILKERTTEL

>gi|198423377|ref|XP_002123273.1| PREDICTED: similar to prostaglandin-endoperoxide synthase 2b [Ciona intestinalis]
MKSVLLQTAVLLVGCILDKCESYDPCCAFPCKHSAICTTLKDDYECDCTGTGFYGRNCEYGYFSTYVTDL
FRPSRSTLHHYMTNYSLLWKLVNNISWLQKKLMAVVLKIRTNYVYEPSPYVGMDSYPTWDSYINKTVYAR
TLPPIPQDCPTPMGTKGPKTLPDIKVLRSLLFQRNKFEPCPMRTNVFFAFFAQHFTHQFFKTNTIKGMPF
QWGEHSVDLSHVYGHTIQRQHELRSHIDGKLKVFETNGEVFPPLTESANVTMSGEKLMRGRKFAIGHPGF
GAFPSFFVIATLWLREHNRVCDILKDLHPDWDDERLFQTARLILTGETLKIIVEDYVQHVSGFHFQLSYD
PEILHKSTFSYNNQIHAEFHILYHWHMLMPDFIELGEHVYPLKELLFNVDPVVEIGMETVLKQLSNQFAG
KVVGGRNQGPELVAVVELALKQTRQMRMCSFNKYRERFGMKPYTSFEELTGETEVAALLRNLYYDIDALE
LFVGYFVEHRRNRQVLGATMLEMGAPYSLKGVFGNPIGSPAWWKPSTFGGEVGFNIIKTTNLKNFICRNV
KGCPDISFKVPQDVPYNSVEGKSSSPNTGIADVLISLTRPQVAQKSQVKELKREEKTNEKSEL

>gi|198427709|ref|XP_002127674.1| PREDICTED: similar to prostaglandin-endoperoxide synthase 2 [Ciona intestinalis]
MPAYYPNLALSSSLKRIVGFSIFKMVAAVTFLGVLTFLLLSNDASTNTDVHYDPCCSFPCQHQSVCTSPD
MISYQCDCTGTGYYGDECQHPYLSTRIKKWIKPSKSTTHYILTHFKWVWTIVNNVSWLRKTLMKAVLAMR
VSSVTEPSPYRGLSSYPSWSAYINDTMYVRTLPPVPTNCPTPMGVKGKPELPEISVLLEKFFKRRTFQPC
PQRTSVLFPFFAQHFTHMFFKTDPMKGMPYQWGDQLVDLSQIYGHGEKRQHELRSHVNGKLKVSLVDGHE
FPPLSNQTTANMSNINLLPQEYQFVFGHQGFSLMPTFLIWSTIWLREHNRICDLIKEENPAWDDERIFQT
ARLVLTGETIKVVIEDYVQHLSGFHYKLLYDPELVQGGSHSFHNQIHVEFQLLYHWHALMPDQIEFNGKS
YTMKRLLFNPEPVVKGGLKRTIEDLSNQWAGQVAGGKTQGAATLHVAGLAIKNGRDLRMQSFNAYKEKFE
MKKYTTFQELTGEEEMAAELQKLYGDIDAVEYYIGIMLEKRRSPQLFGETLTEMGSPYSLKGLYSNPINH
KDWWKPSTFGGQKIMDVIKNTNLQSLICRTVEGCPHASFTVPDGATYRLPSDKQDVENDRTSAILIERAR
NADANKYMWTQDAKPNSIPDKEL

>gi|219415825|ref|XP_002205720.1| hypothetical protein BRAFLDRAFT_68307 [Branchiostoma floridae]
MVYSLSGAPCWLQAGSRIGGQSAGSNIRLTNMAGLLKFGKLHHSQERYSASFRALMAVVETRKDMYQMSY
EANIPDCTLCEPGADLRVLGIGSGSGETDSAILKKLLQRHSSVYNRVVEPSGEMIGRYKTAEEYFQTKDD
TKFHLIHAVHVLYYVEDLDATLRNLWEQLGDGGYMLVAIQSDKGGWGGLRHKLWEKFGQGDRVMTWCSTS
GDVKQCLDTRGISYVTSVDEININVSECFKDDSEAGKLLLDFLTHTPYVSSEPEIKSTALEYIRGLLKLG
KLMHHSPGWYSVNFRAFLAALEMSKDMYQMYGPKVPDLTLCELGADLRVLGIGSGSERYSESFRALIAAV
ETSRYQMSYGPKVPDSTLCEPGTDLRVLGIGSGSGKGDWGGLRHKLWEKFGQGDRDRCSTSDDVKQCLDR
RGISYVTSFDTTNINVSECFKENSENGKLLLDFLTHTPYVSSEPEIKSTALQYIRGRVPVLGHLLALGRA
PHLELTAWRRQYGDVFTIRLGMEDIVVLNGYTAVKDALVDRSELFASRPQSYLLDSTVGFEKADVDCLEV
PLDDLSIVHLRATSASLTPAEIVRNLRLFCIRSTHSQAQEELDAVVGESLPTLSHRSQLPYVNACLLEVM
RIRTLIPVTIHATTQDVEVQGYDIPKGSRNMGVCMREGGGYTCDCTRTGYYGQTRTAKYCNSHHIYISSV
KSYEMHQADRCMSLSCTAELLTALGAALKPSDEMIDHLLFNYKWLWHIINNTQSLRNFLMRLLSKLSVGQ
VDSPPLYHTGHDYTSWDTYSARSYYTRALPPVPADCPTPMGTKGPKELPSPEYLAETFLARRTFLPDTRR
RTNVLFGFMAQHFTHQFFKTDFKKGPGHTWSDHAVDMSHVYGETTERQHQLRSFQDGKLKYQLVDGEVFP
PSLQDAPVHMIYPPNVPEDKRFALGHEFFGHLPGLFVWATVWLREHNRVCDVMKKVHPDWDDERLFQTAR
LILIGETIKIVIEEYVQHLAGNNFQLVWDPELLFEERLQYQNRISVEFNHLYHWHMLMPDHFDINGTMYT
MEDYLFNNDIVLKHGLNATVDAMSRQIAGRVSATYLGHCIYNIIRAPGDAEMAAQLEEAYGDIDAVELYV
GWAMENPMPAGNVLSEMFVRMGSTFSFTGMLSNPICSPGWWKPSTFGGEVGFNLLKTTTLKDLFCRNMNG
PCGLVSFSVPEDVEPTGMPEAVEPAGLPEAEEPTGLPTDEGASQDKHTSQNQEL

>gi|197734865|gb|ACH73269.1| cyclooxygenase [Petromyzon marinus]
HQFFNTDPVRGPAFTRALGHGVDLNHIYGGTLERQHQLRLFKDGKLKFQMIDGEAYPPVVRDAPVHMVYP
EHVPASLRFAVGHEVYGLLPGLLVYATVWLREHNRVCDVLHARHPRWDDERLFQTARLILTGETMKIVIE
EYVQHLSGYNFHLKFDPTLLFGVNFQYSNRMSLEFNHLYHWHPLMPDSLLIDGRNYSYDEFLFNPGLLAD
KKLMPLVRSFMRQRAGTVSGGRNINKNLLHVATSIIEHGRTLRLQSLNQYRHRFNMRPFTSFLELTGDEA
MAAEME

>gi|47221466|emb|CAG08128.1| unnamed protein product [Tetraodon nigroviridis]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>gi|122890728|emb|CAM14110.1| prostaglandin-endoperoxide synthase 1 [Danio rerio]
MRECNFLLKWTVILLLSVSFCAGEESPTSSNTANPCCYYPCQNQGICVRYGLDRYECDCTRTGYYGENCT
IPELWTRVYRLLKPSPNVVHYILTHFDWLWDLINRSFLRDWLMRKVLTVRANLIPSPPTYNSRYDYLNWE
AYSNITYYTRILPPVPNDCPTPMGTKGKIKLPDPKLLVEKFMLRRNFRLDPQGTNLMFAFFAQHFTHQFF
KTHNRVGLGFTKGLGHGVDAGHIYGDSLDRQLELRLHKDGKLKYQVL

>gi|219808025|gb|ACL35628.1| cyclooxygenase-2 [Hippocampus kuda]
WNIINNISFLRNAIMKYVLTSRSHMIDSPPTYNADYHYKSWEAYSNLSYYTRALPPVPQDCPTPMGVVGK
KELPDVKLLAEKLLTRRKFIPDPQGTSLMFAFFAQHFTHQFFKTDMKRGPAFTMAKGHGVDLSHVYGDSL
EKQHKLRLFKDGKLRYQTLDGEMYPPTVKDVGVDMHYPPHVPDSHRFAVGHEAFGLVPGLMMYA

>gi|197734867|gb|ACH73270.1| cyclooxygenase-c [Branchiostoma lanceolatum]
HQFFKTDFKKGAGRTWGDHGVDLSHIYGETVERQHQLRSFTDGKLKFQRVEGEVYPPSLADAPVHMIYPP
YVPEGKRFAIGHEFFGLLPGLFVYSTVWLREHNRVCDVMKELHPDWDDERLFQTARLILTGETINIIINE
YVQHLSGYNFDLFWDPELLFSDQFQYQNRIFVEFNHL

>gi|197734869|gb|ACH73271.1| cyclooxygenase-d [Branchiostoma lanceolatum]
HQFFKTDFKKGPGRTWSDHAVDMSHVYGETVERQRQLRSFQDGKLKYQLVDGEAFPPSLQDASVHMIYPP
DVPEKKRFALGHEFFGLLPGLFVWATVWLREHNRVCDVMKDLHPDWDDERLYQTARLILISETINIVIGE
YVQHLAGKNFQLFWDPELLFEEQXQYQNSIFVEFNHL

>gi|156968376|gb|ABU98644.1| cyclooxygenase-2 [Epinephelus coioides]
AFFSQHFTHQFFKSDMREGPAFTVAKGHGVDLGHIYGDNLERQHKLRLFKDGKLKYQIIDGEVYPPTVKE
VGVDMHYPPHVPDSDRFAVGHEAFGLVPGLMMYAPIWL

>gi|219498304|ref|XP_002245690.1| hypothetical protein BRAFLDRAFT_153094 [Branchiostoma floridae]
FGIPPYKTFLELTGGDAEMADQLEEAYGDVDAVELYVGLMVEQPAPGSVTSETIIEMGGPFSVKGLLSNP
LCSPQWWKPSTFGGEAGFRMVKTATLKNLFCRNT

>gi|33590221|gb|AAQ22672.1| cyclo-oxygenase-2 [Dicentrarchus labrax]
AFFAQHFTHQFFKSDMKKGPAFTVAKGHGVDLSHIYGDKLERQHKLRLFKDGKLKYQMVNGEMYPPTVKE
VGAEMHYPPHVPEAHRFAVGHEAFGLVPGLMMYATIWL

>gi|56967366|gb|AAW31868.1| cyclooxygenase 2 [Salmo salar]
ILTHYKGLWNVINKITFVRNAIMSYVLTSRSHLVDSPPTYNADYGYKSWEAYSNLSYYTRTLPPLPKDCP
TPMGTAGRAVLPDAKLVVEKVLLRKRFIPDPQGSNLMFAFFAQHFTHQFFKSDFMKGPA

>gi|219481257|ref|XP_002237803.1| hypothetical protein BRAFLDRAFT_162714 [Branchiostoma floridae]
FGMAPYRTFLELTAGDAEMAAQLEEAYGDIDAVELYVGWAMENPMPAGNVLSEMFVRMGSTFSFTGMLSN
PICSPGWWKPSTFGGEVGFNLLKTTTLKDLFCRN

>gi|15384976|emb|CAC59825.1| cyclooxygenase-1 [Oncorhynchus mykiss]
HQFFKTRNSMGLGFTRALGHGVDAGNVYGDNLVRQLNLRLLKDGKMKYQVVKGEVYPPTVAEAAVNMRYP
QETPVGQRMAIGQEVFGLLPGL

>gi|219429310|ref|XP_002212444.1| hypothetical protein BRAFLDRAFT_161760 [Branchiostoma floridae]
SYYTRALPPVPEDCPTPMGTKGHKELPSPEYLAQTFLARTTFLPDTRRRTNVLFGFMAQHFTHQFFKTDF
KKGPGRTWSDHAVDMSQVYGETVGRQQQLRTFKDGKLKHQLVDGEVFPPSLQDAPV