>gi|198428656|ref|XP_002125658.1| PREDICTED: similar to cysteine rich protein 61 [Ciona intestinalis]
----------------------------------MRSTSFLIYSLSLVAAFLHFV-----
-------------------------SIVNGMCPLVC--DCSNAP-TRCPSGVSLVTDGCN
C-CKVCAKQTGEECNDQEKVCDPHRDLFCDYSGS-RSGDWGVCRAQ-DGRPCVHEGTRIS
SGTMFQPTCKLRCWCMDGADACTSLC-PHEIQVPLPHV--CPHARLQPIPGQCCSAWVCD
APSGESAVLPMDRFWNEYVSEHEPTDISSSVLPLATVEELGSNVADDVVYESDGGPDGDE
IIDYQLRYVDSPQIDVGDEDSWSETNLIPGEVTRGRSLAGNRKSGCRQQASMWSYCTKSC
GLGVSTRVSNANAECKLRREVRLCEVRSCNQEESLTP-------------KHGRRCMKQR
RAPRKEHIVYS----GCTSVRSYRPRHCGLCV-HGRCCTPRSTRTTTVRFECEDGR--AF
YKRMMVIKSCKC-HRHCTDVMIWNGLPGSHSARSHLAVDS--
>gi|198419990|ref|XP_002127157.1| PREDICTED: similar to connective tissue growth factor [Ciona intestinalis]
---------------------------------------MPATNYVLILSFLVCMTLGVT
EGQIRAF------------------TTESPECRRKCN-NCPPT--PTCAYGVSLIPGKCG
C-CKQCARQLDETCNDDMK-CDPHRNLYCSYSG--VDEHEGVCVAK-PGRACLSSGLTYL
NGESFLIGCKVKCTCMDGVLACENTC-PLTITARAPKN--CRHPQLVKKPNQCCSEWICS
GETLSNNN-----------------------------------------TTNTRPSSSHS
QIRRRHPNTFRPRVI-----AMAAN------RRTPISITVRAKDKCNVQTTEWSACSKTC
GWGVSERVTNDNKACKLRKQSRLCQIRPCSSSFVDNI-------------KRGKKCIRTV
KAQRRVQYSFS----GCQS-KVYTPKYCGACT-DGRCCAPKHTVTKPIKFTCDGGF--QF
KKRMMVIKSCSC-SRRCVGENSFF-----SYRRMGGDTWQE-
>gi|198435966|ref|XP_002131922.1| PREDICTED: similar to connective tissue growth factor [Ciona intestinalis]
MFGYSVLKVSHPTIYIFCFTSNYVVFPFSEIKKWIIVFFVENIKMLFSVYIVMMIVTSQF
YLSMATPNFDLRRSNQSTEGDFYPARSEARECQ-DC--TCPDTP-GTCPPGVSRIMDGCD
C-CKMCAKQLNEPCDVRMR-CDHHKGLYCDMSA-------GLCKAS-PGVACYVGGSWYD
NGQTFQLSCKVTCSCIDGDIACMPTCLPHKPSIRE-----CRHPRLIHRRGECCEEWVC-
--------------------------------------------------TRNGRLDPGI
ELQEHEVKERPVQPV-----VFREN--------------------CMVQTTEWSDCSKSC
GFGVSNRVSNDNADCKLKKEMRLCNIRPCSMTESTVIT------------RR-RSCRKTI
RHSSRVRFSLS----GCLSRDTYRQKYCGFCT--GKCCGPKVSKTIKVQFNCESGT--NF
TRNMMMIKKCSC--SSCPND---FLNLSTYNRAMVGDMVRST
>gi|312283673|ref|NP_001186030.1| WNT1 inducible signaling pathway protein 2 [Danio rerio]
---------------------------------MDRLLRDKRTGELVAWTLLFYLSS---
-------------------------QVCCQQCGSSC--QCQGSV-PSCPEGVPLILDGCQ
C-CQVCARQQGEACSEVFP-CDGQRGLQCDYSAS-FPGEPGECVSQ-KELGCELNGVSYQ
EGQVFQPSCSLQCQCSGGGVTCVPQC-REDVLLPTPD---CPHPRRVQPPGKCCKEWVCE
NLDN----------------------------------------------TVLQDAHIAS
KSDLTLPADSGYQTR------VVSN--------------------CIDQSSEWSACSRTC
GSGISVRVSNQNPSCVLEMQMRLCMIRPCQPVLHRSPQ------------WSRRKCQPSY
RSATPVRLFHQ----GCYSTRFYRPRYCGSCT-DNRCCTPYQTGTAMVTFRCPGGR--LL
NHAVMTINSCIC-HYNCPYSSRGTSFWG--------------
>gi|260810877|ref|XP_002600149.1| hypothetical protein BRAFLDRAFT_276379 [Branchiostoma floridae]
-------------------------------------MKVTQSSVAAVVVFLTCLVHAL-
-------------------------PEGKGGCDGTC--ACPAQP-VTCVPGVRLLEDRCG
CRCKVCASLLGEECSEMAP-CDDTVGLYCDYSAD---KPTGICKAT-FQTPCVFQGKVYQ
SGESFELSCRETCVCQNGAVGCMPLC-PQEVRMPSDD---CPFPQLEKVPGKCCKQWMCD
AKPKEL--------------------------------------------SAKGPMPMIA
GKLERKPETEYPEPV-----------------------------ACLLQATSWSQCSVTC
GMGVSTRVSNHNPECRMQVEKRICQMRPCDLQYLNHIKVRTSLFIKSRGGWDGKKCRSTI
RSMEPSKITFSWYNTRCTTVKAYKWRWCGGCTISGRCCTPYKVKTTTMDFICEDRT--PI
KQDVAWIHSCTC-HRNCPLA----------------------
>gi|169154010|emb|CAQ13700.1| novel protein similar to vertebrate cysteine-rich, angiogenic inducer, 61 (CYR61) [Danio rerio]
-------------------------------------MKMKDFMCLLVLVGIFC------
-------------------------TSGGWGCPQVC--RCPVKR-PVCPAGVSAVPDACG
C-CKVCAAQLNDDCHEGKP-CDHHKGLECNYGND-VSSLHGICRAKLEGRSCEYNGRMYQ
NGENFRAGCKHQCTCIDGAVGCVPLC-PTDIPLSSPS---CPKPRLVKIPGQCCLSLDCH
GESPVLPP--------------------------------------VFRRPQPPPFLLPD
PHTFKKPPAKPKYSLSNELMEVEKR-----------WDKPRSRKHLPAQTTSWTSCSRSC
GMGVSSRVTNENRQCKLMKETRLCNIRPCSSAAVPI--------------KKGRKCSRTQ
KSPEPLRLRYA----GCRSTRLYRPNYCGMCL-DGRCCSPRRTRTVPVLFSCPTGE--RF
ERAVMFVQSCKC-NDDCGSLNDASLPPQ-RWLYGDMHKFID-
>gi|148226312|ref|NP_001085010.1| hypothetical protein LOC432074 [Xenopus laevis]
------------------------------------MRSLAALLPLLQLAALICTGTSG-
-------------------------KLMEASCPTQC--VCPKEV-QSCPPGISLLTDSCG
C-CKVCARQYNQDCGLNHP-CDHIKGLHCDYGAD-PFSPRGICRAKSEGRPCEFFGQIYQ
NGENFQPNCKHQCTCMDGVVGCMPLC-PQEMALPGVD---CINPRLVKVPGQCCEVWQC-
DSNHISEDSGDTTTGDGEDPVRSS--------------EEIGELADIEPVSSNELISLVR
N-GFRVENGLAPLPH-----PGKTT--------------------CAIQTTEWSQCSKSC
NMGVSTRITNDNPHCKLMKETRLCEIRPCQDPFPTMS-------------KNGKKCVRTK
KAKQAVHIPYA----GCTSVRQYKPLYCGSCT-DGRCCTPSKTRTMRVRFRCEDGD--TF
QKSMMWVQKCKC-HQDCPYHSELSYPH--YRLHNDIHKFKD-
>Contig1.[344:838].sp.tr
----------------------------------------MASVLVISALLAVCV-----
-------------------------NLASSSCPAQCP-QCPASL-PQCALGVSLVNDGCG
C-CKVCARQFNQDCSRSEP-CDPLKGLECDSGAD-AAAERGICRAKSEGRTCDYNGKIYQ
HGESFQPNCKHACTCVDGVVGCMPLC-PQELAFPAARLAGCANPRLVKVPGRCCEEWTCD
D-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------
>gi|147904503|ref|NP_001079908.1| cysteine-rich, angiogenic inducer, 61 [Xenopus laevis]
-------------------------------------MSFLALNPVLAIALLSGFI----
-------------------------DLAVSSCPAVC--QCPVEV-PKCAPGVGLVLDGCG
C-CKICAKQLNEDCSKTHP-CDHTKGLECNFGAS-SRAIKGICRAKSEGRPCEYNSKIYQ
NGESFQPNCKHQCTCIDGAVGCLPLC-PQELSLPNLG---CPNPRLVKVPGQCCEEWVCD
EAKDPVDE------------------------MDDFFNKEFGMDTNEGELTRKNEFVAVI
KGGLKMLPVFGSDPQ----SHVVEN------------------SKCIVQTTSWSQCSKTC
GTGISTRVTNDNSNCRLVRETRICEVRPCGQPSYTSL-------------KKGKKCTKTK
KSQAPVRYTYA----GCSSVKKYRPKYCGSCV-DGRCCTPQQTRTVKIRFRCEDGE--TF
TKNVMMIQSCRC-NYNCPHTNEAYPY---YRLFNDIHKFRD-
>gi|62898331|dbj|BAD97105.1| cysteine-rich, angiogenic inducer, 61 variant [Homo sapiens]
------------------------------------MSSRIARALALVVTLLHLT-----
-------------------------RLALSTCPAAC--HCPLEA-PKCAPGVGLVRDGCG
C-CKVCAKQLNEDCSKTQP-CDHTKGLECNFGAS-STALKGICRAQSEGRPCEYNSRIYQ
NGESFQPSCKHQCTCIDGAVGCIPLC-PQELSLPNLG---CPNPRLVKVTGQCCEEWVCD
EDSIKDPM---------------------EDQDGLLGKELGFDASEVELTRNNELIAVGK
GSSLKRLPVFGMEPRILYNPLQGQK--------------------CIVQTTSWSQCSKTC
GTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSL-------------KKGKKCSKTK
KSPEPVRFTYA----GCLSVKKYRPKYCGSRV-DGRCCTPQLTRTVKMRFRCEDGE--TF
SKNVMMIQSCKC-NYNCPHANEAAFPF--YRLFNDIHKFRG-
>gi|260081541|gb|ACX31199.1| cysteine-rich angiogenic inducer 61 protein-like protein 2 [Danio rerio]
--------------------------------MHSGRNQRTRTHTWVVLLFVVCSAD---
-------------------------GEMSRGCPGPC--SCPPSP-PSCPRGVSRVWDNCG
C-CKVCAQQFNQDCGSDLP-CDHIKGLHCHLGAG-GDPQRGLCRAEAHGRPCEFSGRVYQ
HGEDFQTGCEHQCSCIDGVVGCVPLC-PLLVPLPGSH---CTNPRLETPTGHCCQRWVCD
SDNSIREE------------------------------------------ESLPKHTPQY
NHISKLLQEHRSRPA---AQEWSSA---------PVSEIPFPSPGCFSQTTDWSECSASC
GFGVSSRVTNSNAQCRLIRETRLCQITPCDATPHL---------------KKGKKCRRTT
RPRKPELITFA----GCSTVRRYRPRSCGSCV-DDRCCQPRSTRTVRMRFRCPDGE--NI
TRSVMWIQTCRCSKSFCRAKRGRSSPA--VSLHNDIHTFTH-
>gi|260081539|gb|ACX31198.1| cysteine-rich angiogenic inducer 61 protein-like protein 1 [Danio rerio]
---------------------------------MSPLRIILRQGHFFTLVLLSWAT----
-------------------------AEVQGGCPLKC--SCPSAP-PSCPPGISSVLDHCG
C-CRVCARQFNQDCSPTEP-CDHIKGLRCHLGAE-GDPDRGLCRAEAQGRPCELDGRIYQ
HGEDFQPSCEHQCTCVDGVVGCLPLC-PHHISLPDWR---CARRRLIRKPERCCPEWVCD
DDNRIAEV-------------------------------NPVPEAHPAEHTHLTGNELLV
TPSASWDSSAGAPYQ-----EWISS---------SKSR-PIAPATCLLQITDWSPCSATC
GMGVSSRVTNSNPECRLVSETRLCQIRECGVNTAPSL-------------KKGKKCERST
RPQKPVQISFA----GCSTTRRYRLRSCGFCS-DGRLCVPSATRTVRLHFYCPEAERHDF
TRSLMWIQRCSCRHTHSR--RGLNTPAELFNLPNDIHTYTH-
>gi|4507921|ref|NP_003873.1| WNT1-inducible-signaling pathway protein 1 isoform 1 precursor [Homo sapiens]
-------------------------------MRWFLPWTLAAVTAAAASTVLATALSPAP
TTMDFTPAPLEDT------------SSRPQFCKWPC--ECPPSP-PRCPLGVSLITDGCE
C-CKMCAQQLGDNCTEAAI-CDPHRGLYCDYSGDRPRYAIGVCAQV-VGVGCVLDGVRYN
NGQSFQPNCKYNCTCIDGAVGCTPLC--LRVRPPRLW---CPHPRRVSIPGHCCEQWVCE
DDAKRPRK------------------------------------------TAPRDTGAF-
-------DAVGE-VE-----AWHRN--------------------CIAYTSPWSPCSTSC
GLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLI-------------KAGKKCLAVY
QPEASMNFTLA----GCISTRSYQPKYCGVCM-DNRCCIPYKSKTIDVSFQCPDGL--GF
SRQVLWINACFC-NLSCRNPNDIFADLESYPDFSEIAN----
>gi|261259961|ref|NP_001159702.1| WNT1 inducible signaling pathway protein 1a [Danio rerio]
-------------------------------MSWILMWSLLSARAPQIHSASAQDSSNLL
STEEPITPQP---------------YNRSQYCQWPC--KCPKTP-PMCPPGVSLLMDGCD
C-CRACAKQVREACNEKEN-CDHHRGLYCDYSADKPRYEKGVCAFL-PGTGCEHNGVIYR
NGQSFQPNCKYQCLCVNGAIGCVPLC--NESQPPRVW---CQNPQRVKVHGQCCELWICD
ESRRGRK-------------------------------------------TAPRHTMAAL
SSVKK---------------NWHKN--------------------CVAQTTSWSPCSKTC
GRGVSLRITNNNKKCEMVNESRLCNIRPCNVDITKHI-------------KPGKKCLNIY
RAEKPQNFTIS----GCTSTNTYRPKYCGVCT-DERCCIPYKSKTIEVDFQCPNGP--GF
TWQVMWINACFC-NLSCKNPNDIFTDLEQYHEKREI------
>gi|260081535|gb|ACX31196.1| WNT1 inducible signaling pathway protein 1b [Danio rerio]
--------------------------------MWRLLSWILLTSSLHQASFHNSTDSPPM
TTELDP-------------------YNRNRYCKWPC--KCPKSA-LVCPHGVSLLTDGCD
C-CKACAKQAGETCNERDI-CDYHKGLYCDYSADKPRYEKGVCAYV-MGTGCEYNGVIYR
NGQSFQPNCKYRCLCVNGAIGCVPLC--TDSLPPRVW---CQSPKRVKIPGQCCEKWICE
ESRKPRK-------------------------------------------TNPRHAPAEV
STND----------------IWHNN--------------------CIAQTTPWSPCSKTC
GRGISLRISNENAGCVMEKESRLCNLRPCEVDITKHF-------------RPGKKCLNIY
REPEFQNFTIS----GCVSKKPYWPKYCGVCT-DERCCIPYKSKTIEVEFECPDGA--LL
TWKYMWINACFC-NLSCRNPNDIFADLEQYYEFNEIVN----
>gi|48146981|emb|CAG33713.1| NOV [Homo sapiens]
-------------------------------MQSVQSTSFCLRKQCLCLTFLLLHLLGQ-
-------------------------VAATQRCPPQCPGRCPATP-PTCAPGVRAVLDGCS
C-CLVCARQRGESCSDLEP-CDESSGLYCDRSAD-PSKQTGICTAV-EGDNCVFDGVIYR
SGEKFQPSCKFQCTCRDGQIGCVPRC-QLDVLLPEPN---CPAPRKVEVPGECCEKWICG
PDEE----------------------------------------------DSLGGLTLA-
--AYRPEATLGVEVS-----DSSVN--------------------CIEQTTEWTACSKSC
GMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTD------------KKGKKCLRTK
KSLKAIHLQFK----NCTSLHTYKPRFCGVCS-DGRCCTPHNTKTIQAEFQCSPGQ--IV
KKPVMVIGTCTC-HTNCPKNNEAFLQELELKTTRGKI-----
>gi|147905087|ref|NP_001079127.1| protein NOV homolog precursor [Xenopus laevis]
------------------------------------------MTPHLALCFILLIQ----
-------------------------QVASQKCPSQCD-QCPEEP-PSCAPSVLLILDGCG
C-CPVCARQEGESCSHLNP-CQEDKGLYCEFNAD-PRMETGTCMAL-EGNSCVFDGVVYR
NRESFQPSCKYHCTCLNGHIGCVPRC-NLDLLLPGPD---CPFPRRVKVPGECCEKWVCD
SKEE----------------------------------------------MAIGGFAMA-
--AYRPEATLGIDAS-----DTSFA--------------------CIAQTTEWSACSKTC
GMGVSSRVTNRNARCEMQKQIRLCMVRSCEEEPGWHVE------------KKGKKCVRVR
KTTKPIHFHYK----NCTSVQPYKPKFCGQCS-DGRCCTPHSTKTMHVEFVCPQKR--IV
KKPVMVISTCVC-HYNCPQDSSLLQVENARFPGLKTNL----
>gi|148725541|emb|CAN87751.1| novel protein similar to vertebrate connective tissue growth factor (CTGF) [Danio rerio]
------------------------------------MTGTAFTRACIALSLLIH------
-------------------------TAICQDCSQPC--DCPDES-PLCPVGTSLVLDGCS
C-CKVCARQAGEPCSFLEP-CDHHKGLYCDYSVL-SDTETGICMAQ-EGQTCDLGGVIYR
SGETFQPSCKHQCVCMNGEIGCVPTC-ATIIRLPSPD---CPYPRRVQIPGKCCEEWVCD
QIPQE---------------------------------------------DTFQSAVAGR
SIAYREISAHGLQPE-----SARDN--------------------CIVQTTEWSECSATC
GMGVSSRVTNDNEQCQLERQTRMCMIRPCHADLEKDI-------------KRGKKCVRTP
KSQSGMRFELS----GCQSIRLYKPKFCGVCT-DDRCCTPQSTITAEVEFRCPEGD--SF
RKKMMFIKTCSC-HHNCPRENDIFLAS--NSRRMIGDYENDM
>Contig2.[132:857].sp.tr
----------------------------------------MARILVLCVVLIASLY----
-------------------------QAACQQCSNVC--RCPKGP-PVCPVGVSLVADGCG
C-CKVCAKQLGDVCTEADS-CDPHRGLYCAFSTD-LQIRIGVCSAR-DGVPCELGGTMYL
NGESFEPSCKYRCTCVDGAIGCVPLC-AQDVRLPSAD---CPHPRHVKLPGKCCEEWVC-
DGRKEPNS------------------------------------------TPLGGFALP-
--AYRQEETYGPDPE-----SVRDN--------------------CIVQTTEWSACSHTC
GLGVSSRVTNENRQCRLERQTRLCTVRPCDVPL---------------------------
------------------------------------------------------------
------------------------------------------
>gi|62632756|ref|NP_001015041.1| connective tissue growth factor [Danio rerio]
-------------------------------------MFSGMTQSVIALLFLTFLR----
-------------------------WAVAQECSGQC--HCPEVP-PQCSPGVSLVLDTCG
C-CRVCAKQLGELCTERDV-CDPHKGLYCDYGSP-SNRRIGVCTAR-DGATCVFGGMVYR
SGESFQSSCKYQCTCLDGAVGCVPLC-GMDIRLPSPD---CPMPRRVKVPGKCCEEWVCD
SPRQ----------------------------------------------NTFVGSALA-
--AYREEETYGPDPS-----MMREN--------------------CLVQTTEWSACSKTC
GLGISTRVTNDNRECRLEKQSRLCMVRPCESHLEEKI-------------RKGKKCIRTP
RVSKPMKFEIS----GCTTTKSYRPKFCGVCT-DGRCCTPHRTATLPMEFKCPDGQ--VM
KKQMMFIKTCAC-HYNCPGENDIFESM--YYKKMVGDMA---
>gi|147899003|ref|NP_001081697.1| connective tissue growth factor [Xenopus laevis]
-------------------------------------MSAGKVTAVLLFALFCW------
-------------------------VSDAQECNGEC--QCPNKV-PVCDPGVSLVQDGCG
C-CKVCSKQLGELCTERDV-CDPHKGLFCDFGSR-VNRKIGVCTAR-EGAPCVFGGTVYR
SGESFQSSCKYQCTCIDGGVGCVPLC-SMDIRLPSPE---CPFPRRVKLPGKCCEEWVCD
QPQE----------------------------------------------RTLVGPALP-
--AFRMEETYGPDPS-----LIRAN--------------------CLVQTTEWSACSKTC
GMGISTRVTNDNEHCRLEKQSRLCMVRPCEADLEENI-------------KKGKKCIRTP
KISKPVKFEFS----GCTSVKTYRAKFCGVCT-DGRCCTPHRTATLPVEFKCPDGE--VM
KKNMMFIKTCAC-HFNCPGDNDIFEAM--YYRKMYGDMA---
>gi|116241320|sp|P29279.2|CTGF_HUMAN RecName: Full=Connective tissue growth factor; AltName: Full=CCN family member 2; AltName: Full=Hypertrophic chondrocyte-specific protein 24; AltName: Full=Insulin-like growth factor-binding protein 8; Short=IBP-8; Short=IGF-binding protein 8; Short=IGFBP-8; Flags: Precursor
----------------------------------MTAASMGPVRVAFVVLLALCSR----
-------------------------PAVGQNCSGPC--RCPDEPAPRCPAGVSLVLDGCG
C-CRVCAKQLGELCTERDP-CDPHKGLFCHFGSP-ANRKIGVCTAK-DGAPCIFGGTVYR
SGESFQSSCKYQCTCLDGAVGCMPLC-SMDVRLPSPD---CPFPRRVKLPGKCCEEWVCD
EPKD----------------------------------------------QTVVGPALA-
--AYRLEDTFGPDPT-----MIRAN--------------------CLVQTTEWSACSKTC
GMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENI-------------KKGKKCIRTP
KISKPIKFELS----GCTSMKTYRAKFCGVCT-DGRCCTPHRTTTLPVEFKCPDGE--VM
KKNMMFIKTCAC-HYNCPGDNDIFESL--YYRKMYGDMA---