>ref|NP_001545.2|  protein CYR61 precursor [Homo sapiens]
 sp|O00622.1|CYR61_HUMAN  RecName: Full=Protein CYR61; AltName: Full=CCN family member 
1; AltName: Full=Cysteine-rich angiogenic inducer 61; AltName: 
Full=Insulin-like growth factor-binding protein 10; Short=IBP-10; 
Short=IGF-binding protein 10; Short=IGFBP-10; AltName: 
Full=Protein GIG1; Flags: Precursor
 gb|AAB58319.1|  Cyr61 [Homo sapiens]
 15 more sequence titles
 
emb|CAA72802.1|  Gig1 protein [Homo sapiens]
 gb|AAB61240.1|  growth-factor inducible immediate early gene product CYR61 [Homo 
sapiens]
 emb|CAB10848.1|  hCYR61 protein [Homo sapiens]
 gb|AAH01271.1|  Cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
 gb|AAH09199.1|  Cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
 gb|AAH16952.1|  Cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
 gb|AAR05446.1|  cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
 emb|CAG38757.1|  CYR61 [Homo sapiens]
 gb|EAW73196.1|  cysteine-rich, angiogenic inducer, 61, isoform CRA_a [Homo sapiens]
 gb|EAW73198.1|  cysteine-rich, angiogenic inducer, 61, isoform CRA_a [Homo sapiens]
 dbj|BAG37152.1|  unnamed protein product [Homo sapiens]
Length=381

 GENE ID: 3491 CYR61 | cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
(Over 100 PubMed links)

 Score =  780 bits (2014),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 381/381 (100%), Positives = 381/381 (100%), Gaps = 0/381 (0%)

Query  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60
            MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL
Sbjct  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60

Query  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120
            NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ
Sbjct  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120

Query  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180
            CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG
Sbjct  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180

Query  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240
            KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS
Sbjct  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240

Query  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300
            KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
Sbjct  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300

Query  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360
            AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
Sbjct  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360

Query  361  HANEAAFPFYRLFNDIHKFRD  381
            HANEAAFPFYRLFNDIHKFRD
Sbjct  361  HANEAAFPFYRLFNDIHKFRD  381


>emb|CAA72167.1|  CYR61 protein [Homo sapiens]
Length=381

 GENE ID: 3491 CYR61 | cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
(Over 100 PubMed links)

 Score =  779 bits (2011),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 380/381 (99%), Positives = 381/381 (100%), Gaps = 0/381 (0%)

Query  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60
            MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL
Sbjct  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60

Query  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120
            NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ
Sbjct  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120

Query  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180
            CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCD+DSIKDPMEDQDGLLG
Sbjct  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDQDSIKDPMEDQDGLLG  180

Query  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240
            KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS
Sbjct  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240

Query  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300
            KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
Sbjct  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300

Query  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360
            AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
Sbjct  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360

Query  361  HANEAAFPFYRLFNDIHKFRD  381
            HANEAAFPFYRLFNDIHKFRD
Sbjct  361  HANEAAFPFYRLFNDIHKFRD  381


>gb|AAG59863.1|AF307860_1  CYR61 protein [Homo sapiens]
Length=381

 GENE ID: 3491 CYR61 | cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
(Over 100 PubMed links)

 Score =  778 bits (2008),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 380/381 (99%), Positives = 380/381 (99%), Gaps = 0/381 (0%)

Query  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60
            MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL
Sbjct  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60

Query  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120
            NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ
Sbjct  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120

Query  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180
            CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG
Sbjct  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180

Query  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240
            KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS
Sbjct  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240

Query  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300
            KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
Sbjct  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300

Query  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360
            AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
Sbjct  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360

Query  361  HANEAAFPFYRLFNDIHKFRD  381
            HANEAAFP YRLFNDIHKFRD
Sbjct  361  HANEAAFPLYRLFNDIHKFRD  381


>gb|AAB84227.1|  Cyr61 protein [Homo sapiens]
Length=381

 GENE ID: 3491 CYR61 | cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
(Over 100 PubMed links)

 Score =  777 bits (2006),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 379/381 (99%), Positives = 380/381 (99%), Gaps = 0/381 (0%)

Query  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60
            MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL
Sbjct  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60

Query  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120
            NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ
Sbjct  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120

Query  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180
            CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG
Sbjct  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180

Query  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240
            KELGFDASEVELTRNNELIAVGKGSSLKR+PVFGMEPRI YNPLQGQKCIVQTTSWSQCS
Sbjct  181  KELGFDASEVELTRNNELIAVGKGSSLKRIPVFGMEPRIRYNPLQGQKCIVQTTSWSQCS  240

Query  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300
            KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
Sbjct  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300

Query  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360
            AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
Sbjct  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360

Query  361  HANEAAFPFYRLFNDIHKFRD  381
            HANEAAFPFYRLFNDIHKFRD
Sbjct  361  HANEAAFPFYRLFNDIHKFRD  381


>dbj|BAD97105.1|  cysteine-rich, angiogenic inducer, 61 variant [Homo sapiens]
Length=381

 GENE ID: 3491 CYR61 | cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
(Over 100 PubMed links)

 Score =  773 bits (1995),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 378/380 (99%), Positives = 379/380 (99%), Gaps = 0/380 (0%)

Query  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60
            MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL
Sbjct  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60

Query  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120
            NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQP+CKHQ
Sbjct  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPSCKHQ  120

Query  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180
            CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG
Sbjct  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180

Query  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240
            KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS
Sbjct  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240

Query  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300
            KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
Sbjct  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300

Query  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360
            AGCLSVKKYRPKYCGS VDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
Sbjct  301  AGCLSVKKYRPKYCGSRVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360

Query  361  HANEAAFPFYRLFNDIHKFR  380
            HANEAAFPFYRLFNDIHKFR
Sbjct  361  HANEAAFPFYRLFNDIHKFR  380


>dbj|BAG58373.1|  unnamed protein product [Homo sapiens]
Length=357

 GENE ID: 3491 CYR61 | cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
(Over 100 PubMed links)

 Score =  694 bits (1792),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 357/381 (94%), Positives = 357/381 (94%), Gaps = 24/381 (6%)

Query  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60
            MSSRIARALALVVTLLHLTRLALSTC                        GCCKVCAKQL
Sbjct  1    MSSRIARALALVVTLLHLTRLALSTC------------------------GCCKVCAKQL  36

Query  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120
            NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ
Sbjct  37   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  96

Query  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  180
            CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG
Sbjct  97   CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG  156

Query  181  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  240
            KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS
Sbjct  157  KELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCS  216

Query  241  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  300
            KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY
Sbjct  217  KTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTY  276

Query  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360
            AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP
Sbjct  277  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  336

Query  361  HANEAAFPFYRLFNDIHKFRD  381
            HANEAAFPFYRLFNDIHKFRD
Sbjct  337  HANEAAFPFYRLFNDIHKFRD  357


>ref|NP_001079908.1|  cysteine-rich, angiogenic inducer, 61 [Xenopus laevis]
 gb|AAK00947.1|AF320592_1  secreted cysteine-rich protein cyr61 [Xenopus laevis]
 gb|AAH56838.1|  MGC64237 protein [Xenopus laevis]
Length=375

 GENE ID: 379598 cyr61 | cysteine-rich, angiogenic inducer, 61 [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  583 bits (1504),  Expect = 5e-166, Method: Compositional matrix adjust.
 Identities = 298/380 (78%), Positives = 327/380 (86%), Gaps = 7/380 (2%)

Query  3    SRIARALALVVTLLH-LTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLN  61
            S +A    L + LL     LA+S+CPA C CP+E PKCAPGVGLV DGCGCCK+CAKQLN
Sbjct  2    SFLALNPVLAIALLSGFIDLAVSSCPAVCQCPVEVPKCAPGVGLVLDGCGCCKICAKQLN  61

Query  62   EDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQC  121
            EDCSKT PCDHTKGLECNFGASS A+KGICRA+SEGRPCEYNS+IYQNGESFQPNCKHQC
Sbjct  62   EDCSKTHPCDHTKGLECNFGASSRAIKGICRAKSEGRPCEYNSKIYQNGESFQPNCKHQC  121

Query  122  TCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGK  181
            TCIDGAVGC+PLCPQELSLPNLGCPNPRLVKV GQCCEEWVCDE   KDP+++ D    K
Sbjct  122  TCIDGAVGCLPLCPQELSLPNLGCPNPRLVKVPGQCCEEWVCDE--AKDPVDEMDDFFNK  179

Query  182  ELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSK  241
            E G D +E ELTR NE +AV KG  LK LPVFG +P+   + ++  KCIVQTTSWSQCSK
Sbjct  180  EFGMDTNEGELTRKNEFVAVIKG-GLKMLPVFGSDPQ--SHVVENSKCIVQTTSWSQCSK  236

Query  242  TCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYA  301
            TCGTGISTRVTNDN  CRLV+ETRICEVRPCGQP Y+SLKKGKKC+KTKKS  PVR+TYA
Sbjct  237  TCGTGISTRVTNDNSNCRLVRETRICEVRPCGQPSYTSLKKGKKCTKTKKSQAPVRYTYA  296

Query  302  GCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPH  361
            GC SVKKYRPKYCGSCVDGRCCTPQ TRTVK+RFRCEDGETF+KNVMMIQSC+CNYNCPH
Sbjct  297  GCSSVKKYRPKYCGSCVDGRCCTPQQTRTVKIRFRCEDGETFTKNVMMIQSCRCNYNCPH  356

Query  362  ANEAAFPFYRLFNDIHKFRD  381
             NE A+P+YRLFNDIHKFRD
Sbjct  357  TNE-AYPYYRLFNDIHKFRD  375


>gb|EAW73197.1|  cysteine-rich, angiogenic inducer, 61, isoform CRA_b [Homo sapiens]
Length=314

 GENE ID: 3491 CYR61 | cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
(Over 100 PubMed links)

 Score =  578 bits (1489),  Expect = 2e-164, Method: Compositional matrix adjust.
 Identities = 293/303 (97%), Positives = 294/303 (97%), Gaps = 0/303 (0%)

Query  79   NFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQEL  138
            NF     +L  I  AQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQEL
Sbjct  12   NFIPFYLSLLVIFAAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQEL  71

Query  139  SLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNEL  198
            SLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNEL
Sbjct  72   SLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNEL  131

Query  199  IAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPEC  258
            IAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPEC
Sbjct  132  IAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPEC  191

Query  259  RLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCV  318
            RLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCV
Sbjct  192  RLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCV  251

Query  319  DGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHK  378
            DGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHK
Sbjct  252  DGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHK  311

Query  379  FRD  381
            FRD
Sbjct  312  FRD  314


>gb|AAF21597.1|AF003114_1  tumor RMS cell line RD specific product [Homo sapiens]
Length=334

 GENE ID: 3491 CYR61 | cysteine-rich, angiogenic inducer, 61 [Homo sapiens]
(Over 100 PubMed links)

 Score =  560 bits (1442),  Expect = 8e-159, Method: Compositional matrix adjust.
 Identities = 295/339 (87%), Positives = 298/339 (88%), Gaps = 12/339 (4%)

Query  49   GCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQ  108
            GCG        L    S T    HTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQ
Sbjct  2    GCGTHPNLCIHLGHTASPTSYKHHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQ  61

Query  109  NGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSI  168
            NGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSI
Sbjct  62   NGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSI  121

Query  169  KDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQK  228
            KDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKR+PVFGMEPRI YNPLQGQK
Sbjct  122  KDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRIPVFGMEPRIRYNPLQGQK  181

Query  229  CIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSK  288
            CIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSK
Sbjct  182  CIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSK  241

Query  289  TKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVM  348
            TKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRT      CED     +   
Sbjct  242  TKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRT------CEDAVPLRRWGD  295

Query  349  MIQS------CKCNYNCPHANEAAFPFYRLFNDIHKFRD  381
            + Q        KCNYNCPHANEAAFPFYRLFNDIHKFRD
Sbjct  296  IFQERHDDPVLKCNYNCPHANEAAFPFYRLFNDIHKFRD  334


>ref|NP_001001826.1|  protein CYR61 [Danio rerio]
 gb|AAH67668.1|  Zgc:85866 [Danio rerio]
Length=369

 GENE ID: 403033 zgc:85866 | zgc:85866 [Danio rerio] (10 or fewer PubMed links)

 Score =  520 bits (1338),  Expect = 9e-147, Method: Compositional matrix adjust.
 Identities = 251/376 (67%), Positives = 306/376 (81%), Gaps = 11/376 (3%)

Query  8    ALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKT  67
            A A++V  +    +  S+CPA C C  +AP+C PGVGL RD CGCC VCA+QLNEDCS++
Sbjct  3    AWAVIVIFIAHLDMVSSSCPAVCSCAPDAPQCPPGVGLQRDTCGCCLVCARQLNEDCSRS  62

Query  68   QPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGA  127
            +PCDH+KGLECN+GAS  A +GICRA+SEGRPCEY+SRIYQNGESFQPNCKHQCTC+DGA
Sbjct  63   EPCDHSKGLECNYGASHGATRGICRAKSEGRPCEYSSRIYQNGESFQPNCKHQCTCMDGA  122

Query  128  VGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPM-EDQDGLLG-KELGF  185
            VGC+PLCPQELSLP LGC NPRLVKV G+CCEEWVCD++     + E  + + G KE+G 
Sbjct  123  VGCVPLCPQELSLPALGCANPRLVKVPGRCCEEWVCDDEQQGGKLIESANKMPGNKEVGG  182

Query  186  DASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGT  245
            D SE ELT  NELI+V   + LK LP F           Q +KCIVQTT WSQCS++CGT
Sbjct  183  D-SEKELTNKNELISVIMNTKLKSLPAFRSH--------QMEKCIVQTTGWSQCSRSCGT  233

Query  246  GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLS  305
            GISTR+TN+N EC+L+KE+RICEVRPC Q  ++SLKKGKKC++TKKS  PV+F+YAGC S
Sbjct  234  GISTRITNNNAECKLMKESRICEVRPCSQSPHTSLKKGKKCNRTKKSVTPVKFSYAGCSS  293

Query  306  VKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEA  365
            +KKYRP++CGSCVDGRCC+PQ TRT++++FRC+DGETF+KNVMMI+SCKC  +CPHA+EA
Sbjct  294  LKKYRPRFCGSCVDGRCCSPQNTRTIRVKFRCQDGETFNKNVMMIESCKCTKHCPHASEA  353

Query  366  AFPFYRLFNDIHKFRD  381
             FPFYRL+NDIHKF D
Sbjct  354  GFPFYRLYNDIHKFTD  369


>gb|AAH57506.1|  Zgc:85866 protein [Danio rerio]
Length=400

 GENE ID: 403033 zgc:85866 | zgc:85866 [Danio rerio] (10 or fewer PubMed links)

 Score =  502 bits (1293),  Expect = 2e-141, Method: Compositional matrix adjust.
 Identities = 244/376 (65%), Positives = 299/376 (80%), Gaps = 19/376 (5%)

Query  8    ALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKT  67
            A A++V  +    +  S+CPA C C  +AP+        RD CGCC VCA+QLNEDCS++
Sbjct  42   AWAVIVIFIAHFNMVSSSCPAVCSCAPDAPQ--------RDACGCCLVCARQLNEDCSRS  93

Query  68   QPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGA  127
            +PCDH+KGLECN+GAS  A +GICRA+SEGRPCEY+SRIYQNGESFQPNCKHQCTC+DGA
Sbjct  94   EPCDHSKGLECNYGASHGATRGICRAKSEGRPCEYSSRIYQNGESFQPNCKHQCTCMDGA  153

Query  128  VGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPM-EDQDGLLG-KELGF  185
            VGC+PLCPQELSLP LGC NPRL KV G+CCEEWVCD++     + E  + + G KE+G 
Sbjct  154  VGCVPLCPQELSLPALGCANPRLAKVPGRCCEEWVCDDEQQGGKLIESANKMPGNKEVGG  213

Query  186  DASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGT  245
            D SE ELT  NELI+V   + LK LP F           Q +KCIVQTT WSQCS++CGT
Sbjct  214  D-SEKELTNKNELISVIMNTKLKSLPAF--------RSHQMEKCIVQTTGWSQCSRSCGT  264

Query  246  GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLS  305
            GISTR+TN+N EC+L+KE+RICEVRPC Q  ++SLKKGKKC++TKKS  PV+F+YAGC S
Sbjct  265  GISTRITNNNAECKLMKESRICEVRPCSQSPHTSLKKGKKCNRTKKSVMPVKFSYAGCSS  324

Query  306  VKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEA  365
            +KKYRP++CGSCVDGRCC+PQ TRT++++FRC+DGETF+KNVMMI+SCKC  +CPHA+EA
Sbjct  325  LKKYRPRFCGSCVDGRCCSPQNTRTIRVKFRCQDGETFNKNVMMIESCKCTKHCPHASEA  384

Query  366  AFPFYRLFNDIHKFRD  381
             FPFYRL+NDIHKF D
Sbjct  385  GFPFYRLYNDIHKFTD  400


>ref|NP_001085010.1|  hypothetical protein LOC432074 [Xenopus laevis]
 gb|AAH71021.1|  MGC82209 protein [Xenopus laevis]
Length=385

 GENE ID: 432074 MGC82209 | hypothetical protein MGC82209 [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  417 bits (1073),  Expect = 4e-116, Method: Compositional matrix adjust.
 Identities = 198/369 (54%), Positives = 262/369 (71%), Gaps = 14/369 (4%)

Query  20   RLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECN  79
            +L  ++CP  C CP E   C PG+ L+ D CGCCKVCA+Q N+DC    PCDH KGL C+
Sbjct  24   KLMEASCPTQCVCPKEVQSCPPGISLLTDSCGCCKVCARQYNQDCGLNHPCDHIKGLHCD  83

Query  80   FGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELS  139
            +GA   + +GICRA+SEGRPCE+  +IYQNGE+FQPNCKHQCTC+DG VGC+PLCPQE++
Sbjct  84   YGADPFSPRGICRAKSEGRPCEFFGQIYQNGENFQPNCKHQCTCMDGVVGCMPLCPQEMA  143

Query  140  LPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMED------QDGLLGKELGFDASEVELT  193
            LP + C NPRLVKV GQCCE W CD + I +   D      +D +   E   + +++E  
Sbjct  144  LPGVDCINPRLVKVPGQCCEVWQCDSNHISEDSGDTTTGDGEDPVRSSEEIGELADIEPV  203

Query  194  RNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQ-KCIVQTTSWSQCSKTCGTGISTRVT  252
             +NELI++ +         F +E  +   P  G+  C +QTT WSQCSK+C  G+STR+T
Sbjct  204  SSNELISLVRNG-------FRVENGLAPLPHPGKTTCAIQTTEWSQCSKSCNMGVSTRIT  256

Query  253  NDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPK  312
            NDNP C+L+KETR+CE+RPC  P  +  K GKKC +TKK+ + V   YAGC SV++Y+P 
Sbjct  257  NDNPHCKLMKETRLCEIRPCQDPFPTMSKNGKKCVRTKKAKQAVHIPYAGCTSVRQYKPL  316

Query  313  YCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRL  372
            YCGSC DGRCCTP  TRT+++RFRCEDG+TF K++M +Q CKC+ +CP+ +E ++P YRL
Sbjct  317  YCGSCTDGRCCTPSKTRTMRVRFRCEDGDTFQKSMMWVQKCKCHQDCPYHSELSYPHYRL  376

Query  373  FNDIHKFRD  381
             NDIHKF+D
Sbjct  377  HNDIHKFKD  385


>ref|NP_001108294.1|  hypothetical protein LOC100137691 [Xenopus laevis]
 gb|AAI57731.1|  LOC100137691 protein [Xenopus laevis]
Length=385

 GENE ID: 100137691 LOC100137691 | hypothetical protein LOC100137691
[Xenopus laevis] (10 or fewer PubMed links)

 Score =  416 bits (1069),  Expect = 1e-115, Method: Compositional matrix adjust.
 Identities = 201/370 (54%), Positives = 260/370 (70%), Gaps = 16/370 (4%)

Query  20   RLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECN  79
            +L  ++CP  C CP EA  C PG+ LV D CGCCKVCA+Q N+DC    PCDH KGL C+
Sbjct  24   KLMEASCPTQCVCPKEAQSCPPGISLVMDSCGCCKVCARQYNQDCGLNHPCDHIKGLHCD  83

Query  80   FGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELS  139
            FGA  ++  GICRA+SEGR CE+  +IYQNGE+FQPNCKHQCTC+DG VGC+PLCPQE++
Sbjct  84   FGADPSSPMGICRAKSEGRSCEFFGQIYQNGENFQPNCKHQCTCMDGVVGCMPLCPQEMA  143

Query  140  LPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGK-------ELGFDASEVEL  192
            LP + C NPRLVKV GQCCE W CD + I +   D     G+       E+G + +++E 
Sbjct  144  LPGVDCINPRLVKVPGQCCEMWQCDSNHIPEDSGDTTTADGEDPLRSFAEIG-NQADIEP  202

Query  193  TRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQ-KCIVQTTSWSQCSKTCGTGISTRV  251
              +NELI++ +         F +E  +   P  G+  C +QTT WSQCSK+C  G+STR+
Sbjct  203  VSSNELISLVRNG-------FRVENGLAPLPHPGRTACAIQTTEWSQCSKSCDMGVSTRI  255

Query  252  TNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRP  311
            TNDNP+C+L+KETR+CE+RPC  P     K GKKC +TKK+ + V   YAGC S+++Y+P
Sbjct  256  TNDNPQCKLMKETRLCEIRPCQDPFPMKPKNGKKCVRTKKAKQAVHIKYAGCTSMRQYKP  315

Query  312  KYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYR  371
             YCGSC DGRCCTP  TRT+++RF CEDG+TF K+VM +Q CKC  NCP+ +E ++P YR
Sbjct  316  LYCGSCTDGRCCTPSKTRTMRVRFHCEDGDTFQKSVMWVQKCKCYQNCPYHSELSYPHYR  375

Query  372  LFNDIHKFRD  381
            L NDIHKF D
Sbjct  376  LHNDIHKFMD  385


>ref|XP_688534.5|  PREDICTED: protein CYR61 [Danio rerio]
Length=365

 GENE ID: 497580 si:ch211-106h11.3 | si:ch211-106h11.3 [Danio rerio]

 Score =  362 bits (929),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 187/368 (51%), Positives = 243/368 (66%), Gaps = 22/368 (6%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            CP  C CP + P C  GV  V D CGCCKVCA QLN+DC + +PCDH KGLECN+G   +
Sbjct  8    CPQVCRCPAKRPVCPAGVSAVPDACGCCKVCAAQLNDDCHEGKPCDHHKGLECNYGNDVS  67

Query  86   ALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGC  145
            +L GICRA+ EGR CEYN R+YQNGE+F+  CKHQCTCIDGAVGC+PLCP ++ L +  C
Sbjct  68   SLHGICRAKLEGRSCEYNGRMYQNGENFRAGCKHQCTCIDGAVGCVPLCPTDIPLSSPSC  127

Query  146  PNPRLVKVTGQCCEEWVCDEDSIKDP-----MEDQDGLLGKELGFD--ASEVELTRNNEL  198
            P PRLVK+ GQCC    C  +S   P      +    LL     F    ++ + + +NEL
Sbjct  128  PKPRLVKIPGQCCLSLDCHGESPVLPPVFRRPQPPPFLLPDPHTFKKPPAKPKYSLSNEL  187

Query  199  IAV----GKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTND  254
            + V     K  S K LP +            G++C+ QTTSW+ CS++CG G+S+RVTN+
Sbjct  188  MEVEKRWDKPRSRKHLPAWKQA---------GRQCVAQTTSWTSCSRSCGMGVSSRVTNE  238

Query  255  NPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYC  314
            N +C+L+KETR+C +RPC       +KKG+KCS+T+KSPEP+R  YAGC S + YRP YC
Sbjct  239  NAQCKLMKETRLCNIRPCSSAAV-PIKKGRKCSRTQKSPEPLRLRYAGCRSTRLYRPNYC  297

Query  315  GSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYR-LF  373
            G C+DGRCC+P+ TRTV + F C  GE F + VM +QSCKCN +C   N+A+ P  R L+
Sbjct  298  GMCLDGRCCSPRRTRTVPVLFSCPTGERFERAVMFVQSCKCNDDCGSLNDASLPPQRWLY  357

Query  374  NDIHKFRD  381
             D+HKF D
Sbjct  358  GDMHKFID  365


>emb|CAQ13700.1|  novel protein similar to vertebrate cysteine-rich, angiogenic 
inducer, 61 (CYR61) [Danio rerio]
Length=371

 GENE ID: 497580 si:ch211-106h11.3 | si:ch211-106h11.3 [Danio rerio]

 Score =  352 bits (903),  Expect = 3e-96, Method: Compositional matrix adjust.
 Identities = 185/368 (50%), Positives = 238/368 (65%), Gaps = 32/368 (9%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            CP  C CP++ P C  GV  V D CGCCKVCA QLN+DC + +PCDH KGLECN+G   +
Sbjct  24   CPQVCRCPVKRPVCPAGVSAVPDACGCCKVCAAQLNDDCHEGKPCDHHKGLECNYGNDVS  83

Query  86   ALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGC  145
            +L GICRA+ EGR CEYN R+YQNGE+F+  CKHQCTCIDGAVGC+PLCP ++ L +  C
Sbjct  84   SLHGICRAKLEGRSCEYNGRMYQNGENFRAGCKHQCTCIDGAVGCVPLCPTDIPLSSPSC  143

Query  146  PNPRLVKVTGQCCEEWVCDEDSIKDPM-----EDQDGLLGKELGFD--ASEVELTRNNEL  198
            P PRLVK+ GQCC    C  +S   P      +    LL     F    ++ + + +NEL
Sbjct  144  PKPRLVKIPGQCCLSLDCHGESPVLPPVFRRPQPPPFLLPDPHTFKKPPAKPKYSLSNEL  203

Query  199  IAV----GKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTND  254
            + V     K  S K LP                    QTTSW+ CS++CG G+S+RVTN+
Sbjct  204  MEVEKRWDKPRSRKHLPA-------------------QTTSWTSCSRSCGMGVSSRVTNE  244

Query  255  NPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYC  314
            N +C+L+KETR+C +RPC       +KKG+KCS+T+KSPEP+R  YAGC S + YRP YC
Sbjct  245  NRQCKLMKETRLCNIRPCSSAAVP-IKKGRKCSRTQKSPEPLRLRYAGCRSTRLYRPNYC  303

Query  315  GSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYR-LF  373
            G C+DGRCC+P+ TRTV + F C  GE F + VM +QSCKCN +C   N+A+ P  R L+
Sbjct  304  GMCLDGRCCSPRRTRTVPVLFSCPTGERFERAVMFVQSCKCNDDCGSLNDASLPPQRWLY  363

Query  374  NDIHKFRD  381
             D+HKF D
Sbjct  364  GDMHKFID  371


>ref|NP_001892.1|  connective tissue growth factor precursor [Homo sapiens]
 gb|AAA91279.1|  connective tissue growth factor [Homo sapiens]
 emb|CAA55544.1|  connective tissue growth factor [Homo sapiens]
 12 more sequence titles
 
gb|AAQ95223.1|  connective tissue growth factor [Homo sapiens]
 gb|AAS55639.1|  connective tissue growth factor [Homo sapiens]
 emb|CAG46559.1|  CTGF [Homo sapiens]
 gb|AAV38597.1|  connective tissue growth factor [Homo sapiens]
 gb|AAV38598.1|  connective tissue growth factor [Homo sapiens]
 gb|AAH87839.1|  Connective tissue growth factor [Homo sapiens]
 gb|AAZ29611.1|  connective tissue growth factor [Homo sapiens]
 dbj|BAF83573.1|  unnamed protein product [Homo sapiens]
 gb|ADL14512.1|  connective tissue growth factor [Homo sapiens]
Length=349

 GENE ID: 1490 CTGF | connective tissue growth factor [Homo sapiens]
(Over 100 PubMed links)

 Score =  324 bits (830),  Expect = 6e-88, Method: Compositional matrix adjust.
 Identities = 175/373 (47%), Positives = 232/373 (62%), Gaps = 40/373 (11%)

Query  9    LALVVTLLHLTRLALS-TCPAACHCPLE-APKCAPGVGLVRDGCGCCKVCAKQLNEDCSK  66
            +A VV L   +R A+   C   C CP E AP+C  GV LV DGCGCC+VCAKQL E C++
Sbjct  11   VAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTE  70

Query  67   TQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDG  126
              PCD  KGL C+FG+ +    G+C A+ +G PC +   +Y++GESFQ +CK+QCTC+DG
Sbjct  71   RDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSSCKYQCTCLDG  129

Query  127  AVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFD  186
            AVGC+PLC  ++ LP+  CP PR VK+ G+CCEEWVCDE       +DQ           
Sbjct  130  AVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEP------KDQ-----------  172

Query  187  ASEVELTRNNELIAVGKGSSLKRL-PVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGT  245
                          VG   +  RL   FG +P ++        C+VQTT WS CSKTCG 
Sbjct  173  ------------TVVGPALAAYRLEDTFGPDPTMIR-----ANCLVQTTEWSACSKTCGM  215

Query  246  GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLS  305
            GISTRVTNDN  CRL K++R+C VRPC   +  ++KKGKKC +T K  +P++F  +GC S
Sbjct  216  GISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTS  275

Query  306  VKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEA  365
            +K YR K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++C C+YNCP  N+ 
Sbjct  276  MKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDI  335

Query  366  AFPFY--RLFNDI  376
                Y  +++ D+
Sbjct  336  FESLYYRKMYGDM  348


>sp|P29279.2|CTGF_HUMAN  RecName: Full=Connective tissue growth factor; AltName: Full=CCN 
family member 2; AltName: Full=Hypertrophic chondrocyte-specific 
protein 24; AltName: Full=Insulin-like growth factor-binding 
protein 8; Short=IBP-8; Short=IGF-binding protein 
8; Short=IGFBP-8; Flags: Precursor
 emb|CAC44023.1|  connective tissue growth factor [Homo sapiens]
 gb|EAW48038.1|  connective tissue growth factor, isoform CRA_a [Homo sapiens]
 gb|EAW48039.1|  connective tissue growth factor, isoform CRA_a [Homo sapiens]
Length=349

 GENE ID: 1490 CTGF | connective tissue growth factor [Homo sapiens]
(Over 100 PubMed links)

 Score =  324 bits (830),  Expect = 8e-88, Method: Compositional matrix adjust.
 Identities = 175/373 (47%), Positives = 232/373 (62%), Gaps = 40/373 (11%)

Query  9    LALVVTLLHLTRLALS-TCPAACHCPLE-APKCAPGVGLVRDGCGCCKVCAKQLNEDCSK  66
            +A VV L   +R A+   C   C CP E AP+C  GV LV DGCGCC+VCAKQL E C++
Sbjct  11   VAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTE  70

Query  67   TQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDG  126
              PCD  KGL C+FG+ +    G+C A+ +G PC +   +Y++GESFQ +CK+QCTC+DG
Sbjct  71   RDPCDPHKGLFCHFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSSCKYQCTCLDG  129

Query  127  AVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFD  186
            AVGC+PLC  ++ LP+  CP PR VK+ G+CCEEWVCDE       +DQ           
Sbjct  130  AVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEP------KDQ-----------  172

Query  187  ASEVELTRNNELIAVGKGSSLKRLP-VFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGT  245
                          VG   +  RL   FG +P ++        C+VQTT WS CSKTCG 
Sbjct  173  ------------TVVGPALAAYRLEDTFGPDPTMIR-----ANCLVQTTEWSACSKTCGM  215

Query  246  GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLS  305
            GISTRVTNDN  CRL K++R+C VRPC   +  ++KKGKKC +T K  +P++F  +GC S
Sbjct  216  GISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTS  275

Query  306  VKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEA  365
            +K YR K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++C C+YNCP  N+ 
Sbjct  276  MKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDI  335

Query  366  AFPFY--RLFNDI  376
                Y  +++ D+
Sbjct  336  FESLYYRKMYGDM  348


>dbj|BAG37644.1|  unnamed protein product [Homo sapiens]
Length=349

 GENE ID: 1490 CTGF | connective tissue growth factor [Homo sapiens]
(Over 100 PubMed links)

 Score =  323 bits (829),  Expect = 1e-87, Method: Compositional matrix adjust.
 Identities = 175/373 (47%), Positives = 232/373 (62%), Gaps = 40/373 (11%)

Query  9    LALVVTLLHLTRLALS-TCPAACHCPLE-APKCAPGVGLVRDGCGCCKVCAKQLNEDCSK  66
            +A VV L   +R A+   C   C CP E AP+C  GV LV DGCGCC+VCAKQL E C++
Sbjct  11   VAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTE  70

Query  67   TQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDG  126
              PCD  KGL C+FG+ +    G+C A+ +G PC +   +Y++GESFQ +CK+QCTC+DG
Sbjct  71   RGPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSSCKYQCTCLDG  129

Query  127  AVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFD  186
            AVGC+PLC  ++ LP+  CP PR VK+ G+CCEEWVCDE       +DQ           
Sbjct  130  AVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEP------KDQ-----------  172

Query  187  ASEVELTRNNELIAVGKGSSLKRLP-VFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGT  245
                          VG   +  RL   FG +P ++        C+VQTT WS CSKTCG 
Sbjct  173  ------------TVVGPALAAYRLEDTFGPDPTMIR-----ANCLVQTTEWSACSKTCGM  215

Query  246  GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLS  305
            GISTRVTNDN  CRL K++R+C VRPC   +  ++KKGKKC +T K  +P++F  +GC S
Sbjct  216  GISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTS  275

Query  306  VKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEA  365
            +K YR K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++C C+YNCP  N+ 
Sbjct  276  MKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDI  335

Query  366  AFPFY--RLFNDI  376
                Y  +++ D+
Sbjct  336  FESLYYRKMYGDM  348


>ref|NP_001081697.1|  connective tissue growth factor [Xenopus laevis]
 gb|AAH94492.1|  Ctgf protein [Xenopus laevis]
Length=343

 GENE ID: 398003 ctgf | connective tissue growth factor [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  322 bits (824),  Expect = 3e-87, Method: Compositional matrix adjust.
 Identities = 171/374 (46%), Positives = 225/374 (60%), Gaps = 38/374 (10%)

Query  6    ARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCS  65
             +  A+++  L         C   C CP + P C PGV LV+DGCGCCKVC+KQL E C+
Sbjct  4    GKVTAVLLFALFCWVSDAQECNGECQCPNKVPVCDPGVSLVQDGCGCCKVCSKQLGELCT  63

Query  66   KTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCID  125
            +   CD  KGL C+FG+      G+C A+ EG PC +   +Y++GESFQ +CK+QCTCID
Sbjct  64   ERDVCDPHKGLFCDFGSRVNRKIGVCTAR-EGAPCVFGGTVYRSGESFQSSCKYQCTCID  122

Query  126  GAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGF  185
            G VGC+PLC  ++ LP+  CP PR VK+ G+CCEEWVCD+                    
Sbjct  123  GGVGCVPLCSMDIRLPSPECPFPRRVKLPGKCCEEWVCDQP-------------------  163

Query  186  DASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNP-LQGQKCIVQTTSWSQCSKTCG  244
                       E   VG       LP F ME     +P L    C+VQTT WS CSKTCG
Sbjct  164  ----------QERTLVGPA-----LPAFRMEETYGPDPSLIRANCLVQTTEWSACSKTCG  208

Query  245  TGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCL  304
             GISTRVTNDN  CRL K++R+C VRPC   +  ++KKGKKC +T K  +PV+F ++GC 
Sbjct  209  MGISTRVTNDNEHCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPVKFEFSGCT  268

Query  305  SVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANE  364
            SVK YR K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++C C++NCP  N+
Sbjct  269  SVKTYRAKFCGVCTDGRCCTPHRTATLPVEFKCPDGEVMKKNMMFIKTCACHFNCPGDND  328

Query  365  A--AFPFYRLFNDI  376
               A  + +++ D+
Sbjct  329  IFEAMYYRKMYGDM  342


>emb|CAG46534.1|  CTGF [Homo sapiens]
Length=349

 GENE ID: 1490 CTGF | connective tissue growth factor [Homo sapiens]
(Over 100 PubMed links)

 Score =  321 bits (822),  Expect = 6e-87, Method: Compositional matrix adjust.
 Identities = 174/373 (47%), Positives = 231/373 (62%), Gaps = 40/373 (11%)

Query  9    LALVVTLLHLTRLALS-TCPAACHCPLE-APKCAPGVGLVRDGCGCCKVCAKQLNEDCSK  66
            +A VV L   +R A+   C   C  P E AP+C  GV LV DGCGCC+VCAKQL E C++
Sbjct  11   VAFVVLLALCSRPAVGQNCSGPCRYPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTE  70

Query  67   TQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDG  126
              PCD  KGL C+FG+ +    G+C A+ +G PC +   +Y++GESFQ +CK+QCTC+DG
Sbjct  71   RDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSSCKYQCTCLDG  129

Query  127  AVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFD  186
            AVGC+PLC  ++ LP+  CP PR VK+ G+CCEEWVCDE       +DQ           
Sbjct  130  AVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEP------KDQ-----------  172

Query  187  ASEVELTRNNELIAVGKGSSLKRL-PVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGT  245
                          VG   +  RL   FG +P ++        C+VQTT WS CSKTCG 
Sbjct  173  ------------TVVGPALAAYRLEDTFGPDPTMIR-----ANCLVQTTEWSACSKTCGM  215

Query  246  GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLS  305
            GISTRVTNDN  CRL K++R+C VRPC   +  ++KKGKKC +T K  +P++F  +GC S
Sbjct  216  GISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTS  275

Query  306  VKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEA  365
            +K YR K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++C C+YNCP  N+ 
Sbjct  276  MKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDI  335

Query  366  AFPFY--RLFNDI  376
                Y  +++ D+
Sbjct  336  FESLYYRKMYGDM  348


>ref|NP_001015041.1|  connective tissue growth factor [Danio rerio]
 emb|CAI21100.1|  connective tissue growth factor [Danio rerio]
 gb|AAI15210.1|  Connective tissue growth factor [Danio rerio]
 emb|CAM46907.1|  novel protein similar to vertebrate connective tissue growth 
factor (CTGF) [Danio rerio]
Length=345

 GENE ID: 321449 ctgf | connective tissue growth factor [Danio rerio]
(10 or fewer PubMed links)

 Score =  321 bits (822),  Expect = 6e-87, Method: Compositional matrix adjust.
 Identities = 165/362 (46%), Positives = 223/362 (62%), Gaps = 37/362 (10%)

Query  12   VVTLLHLTRLALST---CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQ  68
            V+ LL LT L  +    C   CHCP   P+C+PGV LV D CGCC+VCAKQL E C++  
Sbjct  9    VIALLFLTFLRWAVAQECSGQCHCPEVPPQCSPGVSLVLDTCGCCRVCAKQLGELCTERD  68

Query  69   PCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAV  128
             CD  KGL C++G+ S    G+C A+ +G  C +   +Y++GESFQ +CK+QCTC+DGAV
Sbjct  69   VCDPHKGLYCDYGSPSNRRIGVCTAR-DGATCVFGGMVYRSGESFQSSCKYQCTCLDGAV  127

Query  129  GCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDAS  188
            GC+PLC  ++ LP+  CP PR VKV G+CCEEWVCD          Q+  +G  L     
Sbjct  128  GCVPLCGMDIRLPSPDCPMPRRVKVPGKCCEEWVCDSPR-------QNTFVGSAL-----  175

Query  189  EVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGIS  248
                            ++ +    +G +P ++      + C+VQTT WS CSKTCG GIS
Sbjct  176  ----------------AAYREEETYGPDPSMMR-----ENCLVQTTEWSACSKTCGLGIS  214

Query  249  TRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKK  308
            TRVTNDN ECRL K++R+C VRPC   +   ++KGKKC +T +  +P++F  +GC + K 
Sbjct  215  TRVTNDNRECRLEKQSRLCMVRPCESHLEEKIRKGKKCIRTPRVSKPMKFEISGCTTTKS  274

Query  309  YRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFP  368
            YRPK+CG C DGRCCTP  T T+ M F+C DG+   K +M I++C C+YNCP  N+    
Sbjct  275  YRPKFCGVCTDGRCCTPHRTATLPMEFKCPDGQVMKKQMMFIKTCACHYNCPGENDIFES  334

Query  369  FY  370
             Y
Sbjct  335  MY  336


>gb|AAB67638.1|  connective tissue growth factor XCTGF [Xenopus laevis]
 gb|AAB67639.1|  connective tissue growth factor XCTGF [Xenopus laevis]
Length=343

 GENE ID: 398003 ctgf | connective tissue growth factor [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  320 bits (820),  Expect = 1e-86, Method: Compositional matrix adjust.
 Identities = 170/374 (45%), Positives = 225/374 (60%), Gaps = 38/374 (10%)

Query  6    ARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCS  65
             +  A+++  L         C   C CP + P C PGV +V+DGCGCCKVC+KQL E C+
Sbjct  4    GKVTAVLLFALFCWVSDAQECNGECQCPNKVPVCDPGVRMVQDGCGCCKVCSKQLGELCT  63

Query  66   KTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCID  125
            +   CD  KGL C+FG+      G+C A+ EG PC +   +Y++GESFQ +CK+QCTCID
Sbjct  64   ERDVCDPHKGLFCDFGSRVNRKIGVCTAR-EGAPCVFGGTVYRSGESFQSSCKYQCTCID  122

Query  126  GAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGF  185
            G VGC+PLC  ++ LP+  CP PR VK+ G+CCEEWVCD+                    
Sbjct  123  GGVGCVPLCSMDIRLPSPECPFPRRVKLPGKCCEEWVCDQP-------------------  163

Query  186  DASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNP-LQGQKCIVQTTSWSQCSKTCG  244
                       E   VG       LP F ME     +P L    C+VQTT WS CSKTCG
Sbjct  164  ----------QERTLVGPA-----LPAFRMEETYGPDPSLIRANCLVQTTEWSACSKTCG  208

Query  245  TGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCL  304
             GISTRVTNDN  CRL K++R+C VRPC   +  ++KKGKKC +T K  +PV+F ++GC 
Sbjct  209  MGISTRVTNDNEHCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPVKFEFSGCT  268

Query  305  SVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANE  364
            SVK YR K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++C C++NCP  N+
Sbjct  269  SVKTYRAKFCGVCTDGRCCTPHRTATLPVEFKCPDGEVMKKNMMFIKTCACHFNCPGDND  328

Query  365  A--AFPFYRLFNDI  376
               A  + +++ D+
Sbjct  329  IFEAMYYRKMYGDM  342


>emb|CAM15967.1|  novel protein (zgc:112060) [Danio rerio]
Length=383

 GENE ID: 550346 cyr61l1 | cysteine-rich, angiogenic inducer 61 like 1
[Danio rerio] (10 or fewer PubMed links)

 Score =  310 bits (793),  Expect = 1e-83, Method: Compositional matrix adjust.
 Identities = 156/348 (45%), Positives = 214/348 (61%), Gaps = 22/348 (6%)

Query  42   GVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCE  101
            G+  V D CGCC+VCA+Q N+DCS T+PCDH KGL C+ GA     +G+CRA+++GRPCE
Sbjct  46   GISSVLDHCGCCRVCARQFNQDCSPTEPCDHIKGLRCHLGAEGDPDRGLCRAEAQGRPCE  105

Query  102  YNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEW  161
             + RIYQ+GE FQP+C+HQCTC+DG VGC+PLCP  +SLP+  C   RL++   +CC EW
Sbjct  106  LDGRIYQHGEDFQPSCEHQCTCVDGVVGCLPLCPHHISLPDWRCARRRLIRKPERCCPEW  165

Query  162  VCDED---SIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGS--SLKRLPVFGME  216
            VCD+D   +  +P+ +            A    LT  NEL+     S  S    P     
Sbjct  166  VCDDDNRIAEVNPVPE---------AHPAEHTHLT-GNELLVTPSASWDSSAGAPYQEWI  215

Query  217  PRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPV  276
                  P+    C++Q T WS CS TCG G+S+RVTN NPECRLV ETR+C++R CG   
Sbjct  216  SSSKSRPIAPATCLLQITDWSPCSATCGIGVSSRVTNSNPECRLVSETRLCQIRECGVNT  275

Query  277  YSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFR  336
              S+KKGKKC ++ +  +PV+ ++AGC + ++YR + CG C DGR C P  TRTV++ F 
Sbjct  276  APSMKKGKKCERSTRPQKPVQISFAGCSTTRRYRLRSCGFCSDGRLCVPSATRTVRLHFH  335

Query  337  CEDGE--TFSKNVMMIQSCKCNYNCPHANEAAFPFYRLF---NDIHKF  379
            C + E   F++++M IQ C C +   H+         LF   NDIH +
Sbjct  336  CPEAERHDFTRSLMWIQRCSCRHT--HSRRGLNTPAELFNLPNDIHTY  381


>ref|NP_001017653.1|  cysteine-rich, angiogenic inducer 61 like 1 [Danio rerio]
 gb|AAH93177.1|  Zgc:112060 [Danio rerio]
 gb|AAI64480.1|  Zgc:112060 protein [Danio rerio]
Length=383

 GENE ID: 550346 cyr61l1 | cysteine-rich, angiogenic inducer 61 like 1
[Danio rerio] (10 or fewer PubMed links)

 Score =  310 bits (793),  Expect = 1e-83, Method: Compositional matrix adjust.
 Identities = 156/348 (45%), Positives = 214/348 (61%), Gaps = 22/348 (6%)

Query  42   GVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCE  101
            G+  V D CGCC+VCA+Q N+DCS T+PCDH KGL C+ GA     +G+CRA+++GRPCE
Sbjct  46   GISSVLDHCGCCRVCARQFNQDCSPTEPCDHIKGLRCHLGAEGDPDRGLCRAEAQGRPCE  105

Query  102  YNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEW  161
             + RIYQ+GE FQP+C+HQCTC+DG VGC+PLCP  +SLP+  C   RL++   +CC EW
Sbjct  106  LDGRIYQHGEDFQPSCEHQCTCVDGVVGCLPLCPHHISLPDWRCARRRLIRKPERCCPEW  165

Query  162  VCDED---SIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGS--SLKRLPVFGME  216
            VCD+D   +  +P+ +            A    LT  NEL+     S  S    P     
Sbjct  166  VCDDDNRIAEVNPVPE---------AHPAEHTHLT-GNELLVTPSASWDSSAGAPYQEWI  215

Query  217  PRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPV  276
                  P+    C++Q T WS CS TCG G+S+RVTN NPECRLV ETR+C++R CG   
Sbjct  216  SSSKSRPIAPATCLLQITDWSPCSATCGIGVSSRVTNSNPECRLVSETRLCQIRECGVNT  275

Query  277  YSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFR  336
              S+KKGKKC ++ +  +PV+ ++AGC + ++YR + CG C DGR C P  TRTV++ F 
Sbjct  276  APSMKKGKKCERSTRPQKPVQISFAGCSTTRRYRLRSCGFCSDGRLCVPSATRTVRLHFH  335

Query  337  CEDGE--TFSKNVMMIQSCKCNYNCPHANEAAFPFYRLF---NDIHKF  379
            C + E   F++++M IQ C C +   H+         LF   NDIH +
Sbjct  336  CPEAERHDFTRSLMWIQRCSCRHT--HSRRGLNTPAELFNLPNDIHTY  381


>gb|ACX31198.1|  cysteine-rich angiogenic inducer 61 protein-like protein 1 [Danio 
rerio]
Length=383

 GENE ID: 550346 cyr61l1 | cysteine-rich, angiogenic inducer 61 like 1
[Danio rerio] (10 or fewer PubMed links)

 Score =  310 bits (793),  Expect = 1e-83, Method: Compositional matrix adjust.
 Identities = 157/348 (45%), Positives = 214/348 (61%), Gaps = 22/348 (6%)

Query  42   GVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCE  101
            G+  V D CGCC+VCA+Q N+DCS T+PCDH KGL C+ GA     +G+CRA+++GRPCE
Sbjct  46   GISSVLDHCGCCRVCARQFNQDCSPTEPCDHIKGLRCHLGAEGDPDRGLCRAEAQGRPCE  105

Query  102  YNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEW  161
             + RIYQ+GE FQP+C+HQCTC+DG VGC+PLCP  +SLP+  C   RL++   +CC EW
Sbjct  106  LDGRIYQHGEDFQPSCEHQCTCVDGVVGCLPLCPHHISLPDWRCARRRLIRKPERCCPEW  165

Query  162  VCDED---SIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGS--SLKRLPVFGME  216
            VCD+D   +  +P+ +            A    LT  NEL+     S  S    P     
Sbjct  166  VCDDDNRIAEVNPVPE---------AHPAEHTHLT-GNELLVTPSASWDSSAGAPYQEWI  215

Query  217  PRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPV  276
                  P+    C++Q T WS CS TCG G+S+RVTN NPECRLV ETR+C++R CG   
Sbjct  216  SSSKSRPIAPATCLLQITDWSPCSATCGMGVSSRVTNSNPECRLVSETRLCQIRECGVNT  275

Query  277  YSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFR  336
              SLKKGKKC ++ +  +PV+ ++AGC + ++YR + CG C DGR C P  TRTV++ F 
Sbjct  276  APSLKKGKKCERSTRPQKPVQISFAGCSTTRRYRLRSCGFCSDGRLCVPSATRTVRLHFY  335

Query  337  CEDGE--TFSKNVMMIQSCKCNYNCPHANEAAFPFYRLF---NDIHKF  379
            C + E   F++++M IQ C C +   H+         LF   NDIH +
Sbjct  336  CPEAERHDFTRSLMWIQRCSCRHT--HSRRGLNTPAELFNLPNDIHTY  381


>emb|CAN87751.1|  novel protein similar to vertebrate connective tissue growth 
factor (CTGF) [Danio rerio]
 gb|ACV90402.1|  connective tissue growth factor-like protein [Danio rerio]
Length=351

 GENE ID: 100124530 si:ch211-173b8.2 | si:ch211-173b8.2 [Danio rerio]
(10 or fewer PubMed links)

 Score =  308 bits (790),  Expect = 3e-83, Method: Compositional matrix adjust.
 Identities = 154/360 (43%), Positives = 217/360 (60%), Gaps = 32/360 (9%)

Query  5    IARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDC  64
              RA   +  L+H        C   C CP E+P C  G  LV DGC CCKVCA+Q  E C
Sbjct  6    FTRACIALSLLIHTA--ICQDCSQPCDCPDESPLCPVGTSLVLDGCSCCKVCARQAGEPC  63

Query  65   SKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCI  124
            S  +PCDH KGL C++   S    GIC AQ EG+ C+    IY++GE+FQP+CKHQC C+
Sbjct  64   SFLEPCDHHKGLYCDYSVLSDTETGICMAQ-EGQTCDLGGVIYRSGETFQPSCKHQCVCM  122

Query  125  DGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELG  184
            +G +GC+P C   + LP+  CP PR V++ G+CCEEWVCD+   +D    Q  + G+ + 
Sbjct  123  NGEIGCVPTCATIIRLPSPDCPYPRRVQIPGKCCEEWVCDQIPQEDTF--QSAVAGRSIA  180

Query  185  FDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCG  244
            +                      + +   G++P    +      CIVQTT WS+CS TCG
Sbjct  181  Y----------------------REISAHGLQPESARD-----NCIVQTTEWSECSATCG  213

Query  245  TGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCL  304
             G+S+RVTNDN +C+L ++TR+C +RPC   +   +K+GKKC +T KS   +RF  +GC 
Sbjct  214  MGVSSRVTNDNEQCQLERQTRMCMIRPCHADLEKDIKRGKKCVRTPKSQSGMRFELSGCQ  273

Query  305  SVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANE  364
            S++ Y+PK+CG C D RCCTPQ T T ++ FRC +G++F K +M I++C C++NCP  N+
Sbjct  274  SIRLYKPKFCGVCTDDRCCTPQSTITAEVEFRCPEGDSFRKKMMFIKTCSCHHNCPREND  333


>ref|NP_001096043.1|  si:ch211-173b8.2 [Danio rerio]
 gb|AAY79171.1|  connective tissue growth factor [Danio rerio]
Length=347

 GENE ID: 100124530 si:ch211-173b8.2 | si:ch211-173b8.2 [Danio rerio]
(10 or fewer PubMed links)

 Score =  301 bits (771),  Expect = 6e-81, Method: Compositional matrix adjust.
 Identities = 153/360 (43%), Positives = 215/360 (60%), Gaps = 36/360 (10%)

Query  5    IARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDC  64
              RA   +  L+H        C   C CP E+P C  G  LV DGC CCKVCA+Q  E C
Sbjct  6    FTRACIALSLLIHTA--ICQDCSQPCDCPDESPLCPVGTSLVLDGCSCCKVCARQAGEPC  63

Query  65   SKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCI  124
            S  +PCDH KGL C++   S    GIC AQ EG+ C+    IY++GE+FQP+CKHQC  +
Sbjct  64   SFLEPCDHHKGLYCDYSVLSDTETGICMAQ-EGQTCDLGGVIYRSGETFQPSCKHQCVSM  122

Query  125  DGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELG  184
            +G +GC+P C   + LP+  CP PR V++ G+CCEEWVCD+   +D  +           
Sbjct  123  NGEIGCVPTCATIIRLPSPDCPYPRRVQIPGKCCEEWVCDQIPQEDTFQS----------  172

Query  185  FDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCG  244
                           AV   ++ + +   G++P    +      CIVQTT WS+CS TCG
Sbjct  173  ---------------AV---AAYREISAHGLQPESARD-----NCIVQTTEWSECSATCG  209

Query  245  TGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCL  304
             G+S+RVTNDN +C+L ++TR+C +RPC   +   +K+GKKC +T KS   +RF  +GC 
Sbjct  210  MGVSSRVTNDNEQCQLERQTRMCMIRPCHADLEKDIKRGKKCVRTPKSQSGMRFELSGCQ  269

Query  305  SVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANE  364
            S++ Y+PK+CG C D RCCTPQ T T ++ FRC +G++F K +M I++C C++NCP  N+
Sbjct  270  SIRLYKPKFCGVCTDDRCCTPQSTITAEVEFRCPEGDSFRKKMMFIKTCSCHHNCPREND  329


>gb|ACX31199.1|  cysteine-rich angiogenic inducer 61 protein-like protein 2 [Danio 
rerio]
Length=373

 GENE ID: 553273 cyr61 | cysteine-rich, angiogenic inducer, 61 [Danio rerio]
(10 or fewer PubMed links)

 Score =  300 bits (767),  Expect = 1e-80, Method: Compositional matrix adjust.
 Identities = 160/339 (47%), Positives = 215/339 (63%), Gaps = 16/339 (5%)

Query  42   GVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCE  101
            GV  V D CGCCKVCA+Q N+DC    PCDH KGL C+ GA     +G+CRA++ GRPCE
Sbjct  48   GVSRVWDNCGCCKVCAQQFNQDCGSDLPCDHIKGLHCHLGAGGDPQRGLCRAEAHGRPCE  107

Query  102  YNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEW  161
            ++ R+YQ+GE FQ  C+HQC+CIDG VGC+PLCP  + LP   C NPRL   TG CC+ W
Sbjct  108  FSGRVYQHGEDFQTGCEHQCSCIDGVVGCVPLCPLLVPLPGSHCTNPRLETPTGHCCQRW  167

Query  162  VCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILY  221
            VCD D   + + +++ L      ++     L  +    A  + SS    PV  +      
Sbjct  168  VCDSD---NSIREEESLPKHTPQYNHISKLLQEHRSRPAAQEWSS---APVSEI------  215

Query  222  NPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLK  281
             P     C  QTT WS+CS +CG G+S+RVTN N +CRL++ETR+C++ PC    +  LK
Sbjct  216  -PFPSPGCFSQTTDWSECSASCGFGVSSRVTNSNAQCRLIRETRLCQITPCDATPH--LK  272

Query  282  KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGE  341
            KGKKC +T +  +P   T+AGC +V++YRP+ CGSCVD RCC P+ TRTV+MRFRC DGE
Sbjct  273  KGKKCRRTTRPRKPELITFAGCSTVRRYRPRSCGSCVDDRCCQPRSTRTVRMRFRCPDGE  332

Query  342  TFSKNVMMIQSCKCNYN-CPHANEAAFPFYRLFNDIHKF  379
              +++VM IQ+C+C+ + C      + P   L NDIH F
Sbjct  333  NITRSVMWIQTCRCSKSFCRAKRGRSSPAVSLHNDIHTF  371


>ref|NP_001074456.1|  cysteine-rich, angiogenic inducer, 61 [Danio rerio]
 gb|AAI31859.1|  Cysteine-rich, angiogenic inducer, 61 [Danio rerio]
Length=346

 GENE ID: 553273 cyr61 | cysteine-rich, angiogenic inducer, 61 [Danio rerio]
(10 or fewer PubMed links)

 Score =  299 bits (766),  Expect = 2e-80, Method: Compositional matrix adjust.
 Identities = 160/339 (47%), Positives = 215/339 (63%), Gaps = 16/339 (5%)

Query  42   GVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCE  101
            GV  V D CGCCKVCA+Q N+DC    PCDH KGL C+ GA     +G+CRA++ GRPCE
Sbjct  21   GVSRVWDNCGCCKVCAQQFNQDCGSDLPCDHIKGLHCHLGAGGDPQRGLCRAEAHGRPCE  80

Query  102  YNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEW  161
            ++ R+YQ+GE FQ  C+HQC+CIDG VGC+PLCP  + LP   C NPRL   TG CC+ W
Sbjct  81   FSGRVYQHGEDFQTGCEHQCSCIDGVVGCVPLCPLLVPLPGSHCTNPRLETPTGHCCQRW  140

Query  162  VCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILY  221
            VCD D   + + +++ L      ++     L  +    A  + SS    PV  +      
Sbjct  141  VCDSD---NSIREEESLPKHTPQYNHISKLLQEHRSRPAAQEWSS---APVSEI------  188

Query  222  NPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLK  281
             P     C  QTT WS+CS +CG G+S+RVTN N +CRL++ETR+C++ PC    +  LK
Sbjct  189  -PFPSPGCFSQTTDWSECSASCGFGVSSRVTNSNAQCRLIRETRLCQITPCDATPH--LK  245

Query  282  KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGE  341
            KGKKC +T +  +P   T+AGC +V++YRP+ CGSCVD RCC P+ TRTV+MRFRC DGE
Sbjct  246  KGKKCRRTTRPRKPELITFAGCSTVRRYRPRSCGSCVDDRCCQPRSTRTVRMRFRCPDGE  305

Query  342  TFSKNVMMIQSCKCNYN-CPHANEAAFPFYRLFNDIHKF  379
              +++VM IQ+C+C+ + C      + P   L NDIH F
Sbjct  306  NITRSVMWIQTCRCSKSFCRAKRGRSSPAVSLHNDIHTF  344


>gb|ABU24342.1|  connective tissue growth factor [Danio rerio]
Length=305

 Score =  291 bits (746),  Expect = 4e-78, Method: Compositional matrix adjust.
 Identities = 154/331 (47%), Positives = 204/331 (62%), Gaps = 37/331 (11%)

Query  12   VVTLLHLTRLALST---CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQ  68
            V+ LL LT L  +    C   CHCP   P+C+PGV LV D CGCC+VCAKQL E C++  
Sbjct  9    VIALLFLTFLRWAVAQECSGQCHCPEVPPQCSPGVSLVLDTCGCCRVCAKQLGELCTERD  68

Query  69   PCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAV  128
             CD  KGL C++G+ S    G+C A+ +G  C +   +Y++GESFQ +CK+QCTC+DGAV
Sbjct  69   VCDPHKGLYCDYGSPSNRRIGVCTAR-DGATCVFGGMVYRSGESFQSSCKYQCTCLDGAV  127

Query  129  GCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDAS  188
            GC+PLC  ++ LP+  CP PR VKV G+CCEEWVCD                ++  F  S
Sbjct  128  GCVPLCGMDIRLPSPDCPMPRRVKVPGKCCEEWVCDSP--------------RQNTFVGS  173

Query  189  EVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGIS  248
             +   R  E               +G +P ++      + C+VQTT WS CSKTCG GIS
Sbjct  174  ALAAYREEE--------------TYGPDPSMMR-----ENCLVQTTEWSACSKTCGLGIS  214

Query  249  TRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKK  308
            TRVTNDN ECRL K++R+C VRPC   +   ++KGKKC +T +  +P++F  +GC + K 
Sbjct  215  TRVTNDNRECRLEKQSRLCMVRPCESHLEEKIRKGKKCIRTPRVSKPMKFEISGCTTTKS  274

Query  309  YRPKYCGSCVDGRCCTPQLTRTVKMRFRCED  339
            YRPK+CG C DGRCCTP  T T+ M F+C D
Sbjct  275  YRPKFCGVCTDGRCCTPHRTATLPMEFKCPD  305


>dbj|BAG52518.1|  unnamed protein product [Homo sapiens]
Length=301

 GENE ID: 1490 CTGF | connective tissue growth factor [Homo sapiens]
(Over 100 PubMed links)

 Score =  288 bits (736),  Expect = 6e-77, Method: Compositional matrix adjust.
 Identities = 151/326 (46%), Positives = 204/326 (63%), Gaps = 38/326 (12%)

Query  54   KVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESF  113
            +VCAKQL E C++  PCD  KGL C+FG+ +    G+C A+ +G PC +   +Y++GESF
Sbjct  10   RVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESF  68

Query  114  QPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPME  173
            Q +CK+QCTC+DGAVGC+PLC  ++ LP+  CP PR VK+ G+CCEEWV DE       +
Sbjct  69   QSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVRDEP------K  122

Query  174  DQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLP-VFGMEPRILYNPLQGQKCIVQ  232
            DQ                         VG   +  RL   FG +P ++        C+VQ
Sbjct  123  DQ-----------------------TVVGPALAAYRLEDTFGPDPTMIR-----ANCLVQ  154

Query  233  TTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKS  292
            TT WS CSKTCG GISTRVTNDN  CRL K++R+C VRPC   +  ++KKGKKC +T K 
Sbjct  155  TTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKI  214

Query  293  PEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQS  352
            P+P++F  +GC S+K YR K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++
Sbjct  215  PKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKT  274

Query  353  CKCNYNCPHANEAAFPFY--RLFNDI  376
            C C+YNCP  N+     Y  +++ D+
Sbjct  275  CACHYNCPGDNDIFESLYYRKMYGDM  300


>ref|NP_001079127.1|  protein NOV homolog precursor [Xenopus laevis]
 sp|P51609.1|NOV_XENLA  RecName: Full=Protein NOV homolog; Short=Xnov; AltName: Full=CCN 
family member 3; Flags: Precursor
 gb|AAB17096.1|  immediate early gene; secreted, extracellular protein involved 
in complex processes such as differentiation [Xenopus laevis]
Length=343

 GENE ID: 373662 nov | nephroblastoma overexpressed gene [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  277 bits (708),  Expect = 1e-73, Method: Compositional matrix adjust.
 Identities = 155/360 (43%), Positives = 198/360 (55%), Gaps = 47/360 (13%)

Query  9    LALVVTLLHLTRLALSTCPAAC-HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKT  67
            LAL   LL + ++A   CP+ C  CP E P CAP V L+ DGCGCC VCA+Q  E CS  
Sbjct  5    LALCFILL-IQQVASQKCPSQCDQCPEEPPSCAPSVLLILDGCGCCPVCARQEGESCSHL  63

Query  68   QPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGA  127
             PC   KGL C F A      G C A  EG  C ++  +Y+N ESFQP+CK+ CTC++G 
Sbjct  64   NPCQEDKGLYCEFNADPRMETGTCMAL-EGNSCVFDGVVYRNRESFQPSCKYHCTCLNGH  122

Query  128  VGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG-----KE  182
            +GC+P C  +L LP   CP PR VKV G+CCE+WVCD    K+ M      +        
Sbjct  123  IGCVPRCNLDLLLPGPDCPFPRRVKVPGECCEKWVCDS---KEEMAIGGFAMAAYRPEAT  179

Query  183  LGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKT  242
            LG DAS+                                       CI QTT WS CSKT
Sbjct  180  LGIDASDTSFA-----------------------------------CIAQTTEWSACSKT  204

Query  243  CGTGISTRVTNDNPECRLVKETRICEVRPC-GQPVYSSLKKGKKCSKTKKSPEPVRFTYA  301
            CG G+S+RVTN N  C + K+ R+C VR C  +P +   KKGKKC + +K+ +P+ F Y 
Sbjct  205  CGMGVSSRVTNRNARCEMQKQIRLCMVRSCEEEPGWHVEKKGKKCVRVRKTTKPIHFHYK  264

Query  302  GCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPH  361
             C SV+ Y+PK+CG C DGRCCTP  T+T+ + F C       K VM+I +C C+YNCP 
Sbjct  265  NCTSVQPYKPKFCGQCSDGRCCTPHSTKTMHVEFVCPQKRIVKKPVMVISTCVCHYNCPQ  324


>gb|AAH72245.1|  Unknown (protein for MGC:82324) [Xenopus laevis]
 gb|AAI70511.1|  Unknown (protein for MGC:197238) [Xenopus laevis]
Length=343

 Score =  276 bits (706),  Expect = 2e-73, Method: Compositional matrix adjust.
 Identities = 154/360 (43%), Positives = 198/360 (55%), Gaps = 47/360 (13%)

Query  9    LALVVTLLHLTRLALSTCPAAC-HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKT  67
            LAL   LL + ++A   CP+ C  CP E P CAP V L+ DGC CC VCA+Q  E CS+ 
Sbjct  5    LALCFILL-IQQVASQRCPSQCDQCPEEPPSCAPSVPLILDGCACCPVCARQEGESCSEL  63

Query  68   QPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGA  127
             PC   KGL C F A      G C A  EG  C ++  +Y+N ESFQP+CK+ CTC++G 
Sbjct  64   HPCQEDKGLYCEFNADPRTEAGTCMAL-EGNSCVFDGVVYRNRESFQPSCKYHCTCLNGH  122

Query  128  VGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG-----KE  182
            +GC+P C  +L LP   CP PR VKV G+CCE+WVCD    K+ M      +        
Sbjct  123  IGCVPRCNLDLLLPGPDCPFPRRVKVPGECCEKWVCDS---KEEMAIGGFAMAAYRPEAT  179

Query  183  LGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKT  242
            LG DAS+                                       CI QTT WS CSKT
Sbjct  180  LGIDASDTSFA-----------------------------------CIAQTTEWSACSKT  204

Query  243  CGTGISTRVTNDNPECRLVKETRICEVRPC-GQPVYSSLKKGKKCSKTKKSPEPVRFTYA  301
            CG G+S+RVTN N  C + K+ R+C VR C  +P +   KKGKKC + +K+ +P+ F Y 
Sbjct  205  CGMGVSSRVTNRNARCEMQKQIRLCMVRSCEEEPGWHVEKKGKKCVRVRKTTKPIHFHYK  264

Query  302  GCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPH  361
             C SV+ Y+PK+CG C DGRCCTP  T+T+ + F C       K VM+I +C C+YNCP 
Sbjct  265  NCTSVQPYKPKFCGQCSDGRCCTPHSTKTMHVEFVCPQKRIVKKPVMVISTCVCHYNCPQ  324


>gb|AAI70512.1|  Unknown (protein for MGC:197239) [Xenopus laevis]
Length=343

 Score =  276 bits (705),  Expect = 2e-73, Method: Compositional matrix adjust.
 Identities = 154/360 (43%), Positives = 198/360 (55%), Gaps = 47/360 (13%)

Query  9    LALVVTLLHLTRLALSTCPAACH-CPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKT  67
            LAL   LL + ++A   CP+ C  CP E P CAP V L+ DGC CC VCA+Q  E CS+ 
Sbjct  5    LALCFILL-IQQVASQKCPSQCDLCPEEPPSCAPSVPLILDGCACCPVCARQEGESCSEL  63

Query  68   QPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGA  127
             PC   KGL C F A      G C A  EG  C ++  +Y+N ESFQP+CK+ CTC++G 
Sbjct  64   HPCQEDKGLYCEFNADPRTEAGTCMAL-EGNSCVFDGVVYRNRESFQPSCKYHCTCLNGH  122

Query  128  VGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLG-----KE  182
            +GC+P C  +L LP   CP PR VKV G+CCE+WVCD    K+ M      +        
Sbjct  123  IGCVPRCNLDLLLPGPDCPFPRRVKVPGECCEKWVCDS---KEEMAIGGFAMAAYRPEAT  179

Query  183  LGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKT  242
            LG DAS+                                       CI QTT WS CSKT
Sbjct  180  LGIDASDTSFA-----------------------------------CIAQTTEWSACSKT  204

Query  243  CGTGISTRVTNDNPECRLVKETRICEVRPC-GQPVYSSLKKGKKCSKTKKSPEPVRFTYA  301
            CG G+S+RVTN N  C + K+ R+C VR C  +P +   KKGKKC + +K+ +P+ F Y 
Sbjct  205  CGMGVSSRVTNRNARCEMQKQIRLCMVRSCEEEPGWHVEKKGKKCVRVRKTTKPIHFHYK  264

Query  302  GCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPH  361
             C SV+ Y+PK+CG C DGRCCTP  T+T+ + F C       K VM+I +C C+YNCP 
Sbjct  265  NCTSVQPYKPKFCGQCSDGRCCTPHSTKTMHVEFVCPQKRIVKKPVMVISTCVCHYNCPQ  324


>emb|CAG33713.1|  NOV [Homo sapiens]
Length=357

 GENE ID: 4856 NOV | nephroblastoma overexpressed gene [Homo sapiens]
(Over 10 PubMed links)

 Score =  273 bits (697),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 153/354 (43%), Positives = 198/354 (56%), Gaps = 37/354 (10%)

Query  22   ALSTCPAAC--HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECN  79
            A   CP  C   CP   P CAPGV  V DGC CC VCA+Q  E CS  +PCD + GL C+
Sbjct  31   ATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCD  90

Query  80   FGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELS  139
              A  +   GIC A  EG  C ++  IY++GE FQP+CK QCTC DG +GC+P C  ++ 
Sbjct  91   RSADPSKQTGICTA-VEGDNCVFDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVL  149

Query  140  LPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELI  199
            LP   CP PR V+V G+CCE+W+C  D       ++D L G  L     E  L      +
Sbjct  150  LPEPNCPAPRKVEVPGECCEKWICGPD-------EEDSLGGLTLAAYRPEATLG-----V  197

Query  200  AVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECR  259
             V   S                       CI QTT W+ CSK+CG G STRVTN N +C 
Sbjct  198  EVSDSSV---------------------NCIEQTTEWTACSKSCGMGFSTRVTNRNRQCE  236

Query  260  LVKETRICEVRPCGQ-PVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCV  318
            ++K+TR+C VRPC Q P   + KKGKKC +TKKS + +   +  C S+  Y+P++CG C 
Sbjct  237  MLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCS  296

Query  319  DGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRL  372
            DGRCCTP  T+T++  F+C  G+   K VM+I +C C+ NCP  NEA      L
Sbjct  297  DGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELEL  350


>gb|AAH15028.1|  Nephroblastoma overexpressed gene [Homo sapiens]
Length=357

 GENE ID: 4856 NOV | nephroblastoma overexpressed gene [Homo sapiens]
(Over 10 PubMed links)

 Score =  273 bits (697),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 153/354 (43%), Positives = 198/354 (56%), Gaps = 37/354 (10%)

Query  22   ALSTCPAAC--HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECN  79
            A   CP  C   CP   P CAPGV  V DGC CC VCA+Q  E CS  +PCD + GL C+
Sbjct  31   ATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCD  90

Query  80   FGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELS  139
              A  +   GIC A  EG  C ++  IY++GE FQP+CK QCTC DG +GC+P C  ++ 
Sbjct  91   RSADPSKQTGICTA-VEGDNCVFDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVL  149

Query  140  LPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELI  199
            LP   CP PR V+V G+CCE+W+C  D       ++D L G  L     E  L      +
Sbjct  150  LPEPNCPAPRKVEVPGECCEKWICGPD-------EEDSLGGLTLAAYRPEATLG-----V  197

Query  200  AVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECR  259
             V   S                       CI QTT W+ CSK+CG G STRVTN N +C 
Sbjct  198  EVSDSSV---------------------NCIEQTTEWTACSKSCGMGFSTRVTNRNRQCE  236

Query  260  LVKETRICEVRPCGQ-PVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCV  318
            ++K+TR+C VRPC Q P   + KKGKKC +TKKS + +   +  C S+  Y+P++CG C 
Sbjct  237  MLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCS  296

Query  319  DGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRL  372
            DGRCCTP  T+T++  F+C  G+   K VM+I +C C+ NCP  NEA      L
Sbjct  297  DGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELEL  350


>ref|NP_002505.1|  protein NOV homolog precursor [Homo sapiens]
 sp|P48745.1|NOV_HUMAN  RecName: Full=Protein NOV homolog; Short=NovH; AltName: Full=CCN 
family member 3; AltName: Full=Insulin-like growth factor-binding 
protein 9; Short=IBP-9; Short=IGF-binding protein 
9; Short=IGFBP-9; AltName: Full=Nephroblastoma-overexpressed 
gene protein homolog; Flags: Precursor
 emb|CAA55146.1|  novH [Homo sapiens]
 emb|CAA65403.1|  nov [Homo sapiens]
 gb|AAL92490.1|  NOVH protein [Homo sapiens]
 gb|EAW91984.1|  nephroblastoma overexpressed gene, isoform CRA_a [Homo sapiens]
 gb|EAW91985.1|  nephroblastoma overexpressed gene, isoform CRA_a [Homo sapiens]
Length=357

 GENE ID: 4856 NOV | nephroblastoma overexpressed gene [Homo sapiens]
(Over 10 PubMed links)

 Score =  272 bits (696),  Expect = 2e-72, Method: Compositional matrix adjust.
 Identities = 153/354 (43%), Positives = 198/354 (56%), Gaps = 37/354 (10%)

Query  22   ALSTCPAAC--HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECN  79
            A   CP  C   CP   P CAPGV  V DGC CC VCA+Q  E CS  +PCD + GL C+
Sbjct  31   ATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCD  90

Query  80   FGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELS  139
              A  +   GIC A  EG  C ++  IY++GE FQP+CK QCTC DG +GC+P C  ++ 
Sbjct  91   RSADPSNQTGICTA-VEGDNCVFDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVL  149

Query  140  LPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELI  199
            LP   CP PR V+V G+CCE+W+C  D       ++D L G  L     E  L      +
Sbjct  150  LPEPNCPAPRKVEVPGECCEKWICGPD-------EEDSLGGLTLAAYRPEATLG-----V  197

Query  200  AVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECR  259
             V   S                       CI QTT W+ CSK+CG G STRVTN N +C 
Sbjct  198  EVSDSSV---------------------NCIEQTTEWTACSKSCGMGFSTRVTNRNRQCE  236

Query  260  LVKETRICEVRPCGQ-PVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCV  318
            ++K+TR+C VRPC Q P   + KKGKKC +TKKS + +   +  C S+  Y+P++CG C 
Sbjct  237  MLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCS  296

Query  319  DGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRL  372
            DGRCCTP  T+T++  F+C  G+   K VM+I +C C+ NCP  NEA      L
Sbjct  297  DGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELEL  350


>dbj|BAG35274.1|  unnamed protein product [Homo sapiens]
Length=357

 GENE ID: 4856 NOV | nephroblastoma overexpressed gene [Homo sapiens]
(Over 10 PubMed links)

 Score =  272 bits (696),  Expect = 3e-72, Method: Compositional matrix adjust.
 Identities = 153/354 (43%), Positives = 198/354 (56%), Gaps = 37/354 (10%)

Query  22   ALSTCPAAC--HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECN  79
            A   CP  C   CP   P CAPGV  V DGC CC VCA+Q  E CS  +PCD + GL C+
Sbjct  31   ATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCD  90

Query  80   FGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELS  139
              A  +   GIC A  EG  C ++  IY++GE FQP+CK QCTC DG +GC+P C  ++ 
Sbjct  91   RSADPSNQTGICTA-VEGDNCVFDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVL  149

Query  140  LPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELI  199
            LP   CP PR V+V G+CCE+W+C  D       ++D L G  L     E  L      +
Sbjct  150  LPEPNCPAPRKVEVPGECCEKWICGPD-------EEDSLGGLTLAAYRPEATLG-----V  197

Query  200  AVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECR  259
             V   S                       CI QTT W+ CSK+CG G STRVTN N +C 
Sbjct  198  EVSDSSV---------------------NCIEQTTEWTACSKSCGMGFSTRVTNGNRQCE  236

Query  260  LVKETRICEVRPCGQ-PVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCV  318
            ++K+TR+C VRPC Q P   + KKGKKC +TKKS + +   +  C S+  Y+P++CG C 
Sbjct  237  MLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCS  296

Query  319  DGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRL  372
            DGRCCTP  T+T++  F+C  G+   K VM+I +C C+ NCP  NEA      L
Sbjct  297  DGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELEL  350


>ref|NP_001159702.1|  WNT1 inducible signaling pathway protein 1a [Danio rerio]
 gb|ACX31197.1|  WNT1 inducible signaling pathway protein 1a [Danio rerio]
Length=360

 GENE ID: 560713 wisp1a | WNT1 inducible signaling pathway protein 1a
[Danio rerio] (10 or fewer PubMed links)

 Score =  271 bits (694),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 145/357 (41%), Positives = 204/357 (57%), Gaps = 47/357 (13%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP   P C PGV L+ DGC CC+ CAKQ+ E C++ + CDH +GL C++ A   
Sbjct  46   CQWPCKCPKTPPMCPPGVSLLMDGCDCCRACAKQVREACNEKENCDHHRGLYCDYSADKP  105

Query  86   AL-KGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
               KG+C A   G  CE+N  IY+NG+SFQPNCK+QC C++GA+GC+PLC  E   P + 
Sbjct  106  RYEKGVC-AFLPGTGCEHNGVIYRNGQSFQPNCKYQCLCVNGAIGCVPLC-NESQPPRVW  163

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
            C NP+ VKV GQCCE W+CDE              G++     +   L            
Sbjct  164  CQNPQRVKVHGQCCELWICDESR-----------RGRKTAPRHTMAAL------------  200

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
            SS+K+                 + C+ QTTSWS CSKTCG G+S R+TN+N +C +V E+
Sbjct  201  SSVKK--------------NWHKNCVAQTTSWSPCSKTCGRGVSLRITNNNKKCEMVNES  246

Query  265  RICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCT  324
            R+C +RPC   +   +K GKKC    ++ +P  FT +GC S   YRPKYCG C D RCC 
Sbjct  247  RLCNIRPCNVDITKHIKPGKKCLNIYRAEKPQNFTISGCTSTNTYRPKYCGVCTDERCCI  306

Query  325  PQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD  381
            P  ++T+++ F+C +G  F+  VM I +C CN +C + N+       +F D+ ++ +
Sbjct  307  PYKSKTIEVDFQCPNGPGFTWQVMWINACFCNLSCKNPND-------IFTDLEQYHE  356


>gb|AAA75378.1|  connective tissue growth factor [Homo sapiens]
Length=275

 GENE ID: 1490 CTGF | connective tissue growth factor [Homo sapiens]
(Over 100 PubMed links)

 Score =  268 bits (685),  Expect = 4e-71, Method: Compositional matrix adjust.
 Identities = 141/309 (46%), Positives = 191/309 (62%), Gaps = 38/309 (12%)

Query  71   DHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGC  130
            D  KGL C+FG+ +    G+C A+ +G PC +   +Y++GESFQ +CK+QCTC+DGAVGC
Sbjct  1    DPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGC  59

Query  131  IPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEV  190
            +PLC  ++ LP+  CP PR VK+ G+CCEEWVCDE       +DQ               
Sbjct  60   MPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEP------KDQ---------------  98

Query  191  ELTRNNELIAVGKGSSLKRLP-VFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGIST  249
                      VG   +  RL   FG +P ++        C+VQTT WS CSKTCG GIST
Sbjct  99   --------TVVGPALAAYRLEDTFGPDPTMIR-----ANCLVQTTEWSACSKTCGMGIST  145

Query  250  RVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKY  309
            RVTNDN  CRL K++R+C VRPC   +  ++KKGKKC +T K  +P++F  +GC S+K Y
Sbjct  146  RVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTY  205

Query  310  RPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPF  369
            R K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++C C+YNCP  N+     
Sbjct  206  RAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESL  265

Query  370  Y--RLFNDI  376
            Y  +++ D+
Sbjct  266  YYRKMYGDM  274


>ref|XP_002125658.1|  PREDICTED: similar to cysteine rich protein 61 [Ciona intestinalis]
Length=426

 GENE ID: 100180049 LOC100180049 | similar to cysteine rich protein 61
[Ciona intestinalis]

 Score =  260 bits (664),  Expect = 1e-68, Method: Compositional matrix adjust.
 Identities = 151/402 (38%), Positives = 207/402 (51%), Gaps = 46/402 (11%)

Query  2    SSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLN  61
            +S +  +L+LV   LH   +    CP  C C     +C  GV LV DGC CCKVCAKQ  
Sbjct  4    TSFLIYSLSLVAAFLHFVSIVNGMCPLVCDCSNAPTRCPSGVSLVTDGCNCCKVCAKQTG  63

Query  62   EDCSKTQP-CDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120
            E+C+  +  CD  + L C++  S +   G+CRAQ +GRPC +      +G  FQP CK +
Sbjct  64   EECNDQEKVCDPHRDLFCDYSGSRSGDWGVCRAQ-DGRPCVHEGTRISSGTMFQPTCKLR  122

Query  121  CTCIDGAVGCIPLCPQELSLP-NLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLL  179
            C C+DGA  C  LCP E+ +P    CP+ RL  + GQCC  WVCD  S +  +   D   
Sbjct  123  CWCMDGADACTSLCPHEIQVPLPHVCPHARLQPIPGQCCSAWVCDAPSGESAVLPMDRFW  182

Query  180  GKELG------FDASEVELTRNNEL---------------------------------IA  200
             + +         +S + L    EL                                 I 
Sbjct  183  NEYVSEHEPTDISSSVLPLATVEELGSNVADDVVYESDGGPDGDEIIDYQLRYVDSPQID  242

Query  201  VGKGSSLKRLPVFGMEPRILYNPLQGQK---CIVQTTSWSQCSKTCGTGISTRVTNDNPE  257
            VG   S     +   E       L G +   C  Q + WS C+K+CG G+STRV+N N E
Sbjct  243  VGDEDSWSETNLIPGEV-TRGRSLAGNRKSGCRQQASMWSYCTKSCGLGVSTRVSNANAE  301

Query  258  CRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSC  317
            C+L +E R+CEVR C Q    + K G++C K +++P      Y+GC SV+ YRP++CG C
Sbjct  302  CKLRREVRLCEVRSCNQEESLTPKHGRRCMKQRRAPRKEHIVYSGCTSVRSYRPRHCGLC  361

Query  318  VDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC  359
            V GRCCTP+ TRT  +RF CEDG  F K +M+I+SCKC+ +C
Sbjct  362  VHGRCCTPRSTRTTTVRFECEDGRAFYKRMMVIKSCKCHRHC  403


>ref|NP_003873.1|  WNT1-inducible-signaling pathway protein 1 isoform 1 precursor 
[Homo sapiens]
 sp|O95388.1|WISP1_HUMAN  RecName: Full=WNT1-inducible-signaling pathway protein 1; Short=WISP-1; 
AltName: Full=CCN family member 4; AltName: Full=Wnt-1-induced 
secreted protein; Flags: Precursor
 gb|AAC96321.1|  connective tissue growth factor related protein WISP-1 [Homo 
sapiens]
 gb|AAH74840.1|  WNT1 inducible signaling pathway protein 1 [Homo sapiens]
 gb|AAH74841.1|  WNT1 inducible signaling pathway protein 1 [Homo sapiens]
 gb|EAW92162.1|  WNT1 inducible signaling pathway protein 1, isoform CRA_a [Homo 
sapiens]
 dbj|BAF85720.1|  unnamed protein product [Homo sapiens]
Length=367

 GENE ID: 8840 WISP1 | WNT1 inducible signaling pathway protein 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  258 bits (658),  Expect = 6e-68, Method: Compositional matrix adjust.
 Identities = 148/386 (38%), Positives = 208/386 (54%), Gaps = 54/386 (14%)

Query  5    IARALALVVTLLHLTRLALST-------CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCA  57
            +A AL+   T +  T   L         C   C CP   P+C  GV L+ DGC CCK+CA
Sbjct  21   LATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCA  80

Query  58   KQLNEDCSKTQPCDHTKGLECNF-GASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPN  116
            +QL ++C++   CD  +GL C++ G       G+C AQ  G  C  +   Y NG+SFQPN
Sbjct  81   QQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVC-AQVVGVGCVLDGVRYNNGQSFQPN  139

Query  117  CKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQD  176
            CK+ CTCIDGAVGC PLC   +  P L CP+PR V + G CCE+WVC++D+ K P +   
Sbjct  140  CKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSIPGHCCEQWVCEDDA-KRPRKTAP  197

Query  177  GLLGKELGFDA-SEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTS  235
               G    FDA  EVE    N                                CI  T+ 
Sbjct  198  RDTG---AFDAVGEVEAWHRN--------------------------------CIAYTSP  222

Query  236  WSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEP  295
            WS CS +CG G+STR++N N +C   +E+R+C +RPC   +++ +K GKKC    +    
Sbjct  223  WSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEAS  282

Query  296  VRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKC  355
            + FT AGC+S + Y+PKYCG C+D RCC P  ++T+ + F+C DG  FS+ V+ I +C C
Sbjct  283  MNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFC  342

Query  356  NYNCPHANEAAFPFYRLFNDIHKFRD  381
            N +C + N+       +F D+  + D
Sbjct  343  NLSCRNPND-------IFADLESYPD  361


>gb|ACX31196.1|  WNT1 inducible signaling pathway protein 1b [Danio rerio]
Length=356

 GENE ID: 792714 wisp1b | WNT1 inducible signaling pathway protein 1b
[Danio rerio] (10 or fewer PubMed links)

 Score =  256 bits (653),  Expect = 2e-67, Method: Compositional matrix adjust.
 Identities = 142/354 (40%), Positives = 194/354 (55%), Gaps = 43/354 (12%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP  A  C  GV L+ DGC CCK CAKQ  E C++   CD+ KGL C++ A   
Sbjct  41   CKWPCKCPKSALVCPHGVSLLTDGCDCCKACAKQAGETCNERDICDYHKGLYCDYSADKP  100

Query  86   AL-KGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
               KG+C A   G  CEYN  IY+NG+SFQPNCK++C C++GA+GC+PLC   L  P + 
Sbjct  101  RYEKGVC-AYVMGTGCEYNGVIYRNGQSFQPNCKYRCLCVNGAIGCVPLCTDSLP-PRVW  158

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
            C +P+ VK+ GQCCE+W+C+E   + P                               + 
Sbjct  159  CQSPKRVKIPGQCCEKWICEES--RKP-------------------------------RK  185

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
            ++ +  P       +  N +    CI QTT WS CSKTCG GIS R++N+N  C + KE+
Sbjct  186  TNPRHAPA-----EVSTNDIWHNNCIAQTTPWSPCSKTCGRGISLRISNENAGCVMEKES  240

Query  265  RICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCT  324
            R+C +RPC   +    + GKKC    + PE   FT +GC+S K Y PKYCG C D RCC 
Sbjct  241  RLCNLRPCEVDITKHFRPGKKCLNIYREPEFQNFTISGCVSKKPYWPKYCGVCTDERCCI  300

Query  325  PQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANE--AAFPFYRLFNDI  376
            P  ++T+++ F C DG   +   M I +C CN +C + N+  A    Y  FN+I
Sbjct  301  PYKSKTIEVEFECPDGALLTWKYMWINACFCNLSCRNPNDIFADLEQYYEFNEI  354


>ref|NP_001107100.1|  WNT1 inducible signaling pathway protein 1b [Danio rerio]
 gb|AAI54631.1|  Zgc:172276 protein [Danio rerio]
 gb|AAI71541.1|  Zgc:172276 [Danio rerio]
 gb|AAI71543.1|  Zgc:172276 [Danio rerio]
Length=356

 GENE ID: 792714 wisp1b | WNT1 inducible signaling pathway protein 1b
[Danio rerio] (10 or fewer PubMed links)

 Score =  256 bits (653),  Expect = 3e-67, Method: Compositional matrix adjust.
 Identities = 143/354 (40%), Positives = 194/354 (55%), Gaps = 43/354 (12%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP  A  C  GV L+ DGC CCK CAKQ  E C++   CD+ KGL C++ A   
Sbjct  41   CKWPCKCPKSALVCPHGVSLLMDGCDCCKACAKQAGETCNERDICDYHKGLYCDYSADKP  100

Query  86   AL-KGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
               KG+C A   G  CEYN  IY+NG+SFQPNCK++C C++GA+GC+PLC   L  P + 
Sbjct  101  RYEKGVC-AYVMGTGCEYNGVIYRNGQSFQPNCKYRCLCVNGAIGCVPLCTDSLP-PRVW  158

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
            C +P+ VK+ GQCCE+W+C+E   + P +       +    + S  ++  NN        
Sbjct  159  CQSPKRVKIPGQCCEKWICEES--RKPRKTNP----RHAPAEVSANDIWHNN--------  204

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
                                    CI QTT WS CSKTCG GIS R++N+N  C + KE+
Sbjct  205  ------------------------CIAQTTPWSPCSKTCGRGISLRISNENAGCVMEKES  240

Query  265  RICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCT  324
            R+C +RPC   +    + GKKC    + PE   FT +GC+S K Y PKYCG C D RCC 
Sbjct  241  RLCNLRPCEVDITKHFRPGKKCLNIYREPEFQNFTISGCVSKKPYWPKYCGVCTDERCCI  300

Query  325  PQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANE--AAFPFYRLFNDI  376
            P  ++T+++ F C DG   +   M I +C CN +C + N+  A    Y  FN+I
Sbjct  301  PYKSKTIEVEFECPDGALLTWKYMWINACFCNLSCRNPNDIFADLEQYYEFNEI  354


>dbj|BAG57572.1|  unnamed protein product [Homo sapiens]
Length=342

 GENE ID: 4856 NOV | nephroblastoma overexpressed gene [Homo sapiens]
(Over 10 PubMed links)

 Score =  255 bits (652),  Expect = 3e-67, Method: Compositional matrix adjust.
 Identities = 146/354 (41%), Positives = 190/354 (54%), Gaps = 52/354 (15%)

Query  22   ALSTCPAAC--HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECN  79
            A   CP  C   CP   P CAPGV  V DGC CC VCA+Q  E CS  +PCD + GL C+
Sbjct  31   ATQRCPPQCPGQCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCD  90

Query  80   FGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELS  139
              A  +                  + IY++GE FQP+CK QCTC DG +GC+P C  ++ 
Sbjct  91   RSADPS----------------NQTVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVL  134

Query  140  LPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELI  199
            LP   CP PR V+V G+CCE+W+C  D       ++D L G  L     E  L      +
Sbjct  135  LPEPNCPAPRKVEVPGECCEKWICGPD-------EEDSLGGLTLAAYRPEATLG-----V  182

Query  200  AVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECR  259
             V   S                       CI QTT W+ CSK+CG G STRVTN N +C 
Sbjct  183  EVSDSSV---------------------NCIEQTTEWTACSKSCGMGFSTRVTNRNRQCE  221

Query  260  LVKETRICEVRPCGQ-PVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCV  318
            ++K+TR+C VRPC Q P   + KKGKKC +TKKS + +   +  C S+  Y+P++CG C 
Sbjct  222  MLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCS  281

Query  319  DGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRL  372
            DGRCCTP  T+T++  F+C  G+   K VM+I +C C+ NCP  NEA      L
Sbjct  282  DGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELEL  335


>dbj|BAF98713.1|  unnamed protein product [Homo sapiens]
Length=367

 GENE ID: 8840 WISP1 | WNT1 inducible signaling pathway protein 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  253 bits (647),  Expect = 1e-66, Method: Compositional matrix adjust.
 Identities = 147/386 (38%), Positives = 207/386 (54%), Gaps = 54/386 (14%)

Query  5    IARALALVVTLLHLTRLALST-------CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCA  57
            +A AL+   T +  T   L         C   C CP   P+C  GV L+ DGC  CK+CA
Sbjct  21   LATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCERCKMCA  80

Query  58   KQLNEDCSKTQPCDHTKGLECNF-GASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPN  116
            +QL ++C++   CD  +GL C++ G       G+C AQ  G  C  +   Y NG+SFQPN
Sbjct  81   QQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVC-AQVVGVGCVLDGVRYNNGQSFQPN  139

Query  117  CKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQD  176
            CK+ CTCIDGAVGC PLC   +  P L CP+PR V + G CCE+WVC++D+ K P +   
Sbjct  140  CKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSIPGHCCEQWVCEDDA-KRPRKTAP  197

Query  177  GLLGKELGFDA-SEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTS  235
               G    FDA  EVE    N                                CI  T+ 
Sbjct  198  RDTG---AFDAVGEVEAWHRN--------------------------------CIAYTSP  222

Query  236  WSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEP  295
            WS CS +CG G+STR++N N +C   +E+R+C +RPC   +++ +K GKKC    +    
Sbjct  223  WSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEAS  282

Query  296  VRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKC  355
            + FT AGC+S + Y+PKYCG C+D RCC P  ++T+ + F+C DG  FS+ V+ I +C C
Sbjct  283  MNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFC  342

Query  356  NYNCPHANEAAFPFYRLFNDIHKFRD  381
            N +C + N+       +F D+  + D
Sbjct  343  NLSCRNPND-------IFADLESYPD  361


>ref|XP_002600149.1|  hypothetical protein BRAFLDRAFT_276379 [Branchiostoma floridae]
 gb|EEN56161.1|  hypothetical protein BRAFLDRAFT_276379 [Branchiostoma floridae]
Length=349

 GENE ID: 7226543 BRAFLDRAFT_276379 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  253 bits (646),  Expect = 2e-66, Method: Compositional matrix adjust.
 Identities = 151/383 (39%), Positives = 205/383 (54%), Gaps = 62/383 (16%)

Query  3    SRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGC-CKVCAKQLN  61
            S +A  +  +  L+H        C   C CP +   C PGV L+ D CGC CKVCA  L 
Sbjct  6    SSVAAVVVFLTCLVHALPEGKGGCDGTCACPAQPVTCVPGVRLLEDRCGCRCKVCASLLG  65

Query  62   EDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQC  121
            E+CS+  PCD T GL C++ A      GIC+A  +  PC +  ++YQ+GESF+ +C+  C
Sbjct  66   EECSEMAPCDDTVGLYCDYSADKPT--GICKATFQ-TPCVFQGKVYQSGESFELSCRETC  122

Query  122  TCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCD----EDSIKDPMEDQDG  177
             C +GAVGC+PLCPQE+ +P+  CP P+L KV G+CC++W+CD    E S K PM    G
Sbjct  123  VCQNGAVGCMPLCPQEVRMPSDDCPFPQLEKVPGKCCKQWMCDAKPKELSAKGPMPMIAG  182

Query  178  LLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWS  237
             L ++   +  E                     PV                C++Q TSWS
Sbjct  183  KLERKPETEYPE---------------------PV---------------ACLLQATSWS  206

Query  238  QCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLK-------------KGK  284
            QCS TCG G+STRV+N NPECR+  E RIC++RPC     + +K              GK
Sbjct  207  QCSVTCGMGVSTRVSNHNPECRMQVEKRICQMRPCDLQYLNHIKVRTSLFIKSRGGWDGK  266

Query  285  KCSKTKKSPEPVRFTYAG----CLSVKKYRPKYCGSC-VDGRCCTPQLTRTVKMRFRCED  339
            KC  T +S EP + T++     C +VK Y+ ++CG C + GRCCTP   +T  M F CED
Sbjct  267  KCRSTIRSMEPSKITFSWYNTRCTTVKAYKWRWCGGCTISGRCCTPYKVKTTTMDFICED  326

Query  340  GETFSKNVMMIQSCKCNYNCPHA  362
                 ++V  I SC C+ NCP A
Sbjct  327  RTPIKQDVAWIHSCTCHRNCPLA  349


>ref|NP_001186030.1|  WNT1 inducible signaling pathway protein 2 [Danio rerio]
 gb|ACX31200.1|  WNT1 inducible signaling pathway protein 2 [Danio rerio]
Length=344

 GENE ID: 100007759 wisp2 | WNT1 inducible signaling pathway protein 2
[Danio rerio] (10 or fewer PubMed links)

 Score =  252 bits (643),  Expect = 4e-66, Method: Compositional matrix adjust.
 Identities = 146/366 (40%), Positives = 199/366 (54%), Gaps = 37/366 (10%)

Query  4    RIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNED  63
            R    +A  +     +++    C ++C C    P C  GV L+ DGC CC+VCA+Q  E 
Sbjct  9    RTGELVAWTLLFYLSSQVCCQQCGSSCQCQGSVPSCPEGVPLILDGCQCCQVCARQQGEA  68

Query  64   CSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTC  123
            CS+  PCD  +GL+C++ AS     G C +Q E   CE N   YQ G+ FQP+C  QC C
Sbjct  69   CSEVFPCDGQRGLQCDYSASFPGEPGECVSQKE-LGCELNGVSYQEGQVFQPSCSLQCQC  127

Query  124  IDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKEL  183
              G V C+P C +++ LP   CP+PR V+  G+CC+EWVC+     D    QD  +    
Sbjct  128  SGGGVTCVPQCREDVLLPTPDCPHPRRVQPPGKCCKEWVCEN---LDNTVLQDAHI----  180

Query  184  GFDASEVELTRNNELIAVGKGSSLKRLPV-FGMEPRILYNPLQGQKCIVQTTSWSQCSKT  242
               AS+ +LT                LP   G + R++ N      CI Q++ WS CS+T
Sbjct  181  ---ASKSDLT----------------LPADSGYQTRVVSN------CIDQSSEWSACSRT  215

Query  243  CGTGISTRVTNDNPECRLVKETRICEVRPCGQPVY--SSLKKGKKCSKTKKSPEPVRFTY  300
            CG+GIS RV+N NP C L  + R+C +RPC QPV   S     +KC  + +S  PVR  +
Sbjct  216  CGSGISVRVSNQNPSCVLEMQMRLCMIRPC-QPVLHRSPQWSRRKCQPSYRSATPVRLFH  274

Query  301  AGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCP  360
             GC S + YRP+YCGSC D RCCTP  T T  + FRC  G   +  VM I SC C+YNCP
Sbjct  275  QGCYSTRFYRPRYCGSCTDNRCCTPYQTGTAMVTFRCPGGRLLNHAVMTINSCICHYNCP  334

Query  361  HANEAA  366
            +++   
Sbjct  335  YSSRGT  340


>ref|XP_002131922.1|  PREDICTED: similar to connective tissue growth factor [Ciona 
intestinalis]
Length=401

 GENE ID: 100176312 LOC100176312 | similar to connective tissue growth factor
[Ciona intestinalis]

 Score =  241 bits (614),  Expect = 7e-63, Method: Compositional matrix adjust.
 Identities = 137/333 (41%), Positives = 189/333 (57%), Gaps = 47/333 (14%)

Query  30   CHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKG  89
            C CP     C PGV  + DGC CCK+CAKQLNE C     CDH KGL C+  A      G
Sbjct  95   CTCPDTPGTCPPGVSRIMDGCDCCKMCAKQLNEPCDVRMRCDHHKGLYCDMSA------G  148

Query  90   ICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLC-PQELSLPNLGCPNP  148
            +C+A S G  C      Y NG++FQ +CK  C+CIDG + C+P C P + S+    C +P
Sbjct  149  LCKA-SPGVACYVGGSWYDNGQTFQLSCKVTCSCIDGDIACMPTCLPHKPSIRE--CRHP  205

Query  149  RLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLK  208
            RL+   G+CCEEWVC  +   DP            G +  E E               +K
Sbjct  206  RLIHRRGECCEEWVCTRNGRLDP------------GIELQEHE---------------VK  238

Query  209  RLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICE  268
              PV   +P +       + C+VQTT WS CSK+CG G+S RV+NDN +C+L KE R+C 
Sbjct  239  ERPV---QPVVFR-----ENCMVQTTEWSDCSKSCGFGVSNRVSNDNADCKLKKEMRLCN  290

Query  269  VRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLT  328
            +RPC     + + + + C KT +    VRF+ +GCLS   YR KYCG C  G+CC P+++
Sbjct  291  IRPCSMTESTVITRRRSCRKTIRHSSRVRFSLSGCLSRDTYRQKYCGFCT-GKCCGPKVS  349

Query  329  RTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPH  361
            +T+K++F CE G  F++N+MMI+ C C+ +CP+
Sbjct  350  KTIKVQFNCESGTNFTRNMMMIKKCSCS-SCPN  381


>gb|AAI07646.1|  Ctgf protein [Danio rerio]
Length=249

 GENE ID: 321449 ctgf | connective tissue growth factor [Danio rerio]
(10 or fewer PubMed links)

 Score =  224 bits (572),  Expect = 6e-58, Method: Compositional matrix adjust.
 Identities = 125/274 (46%), Positives = 163/274 (59%), Gaps = 37/274 (14%)

Query  12   VVTLLHLTRLALST---CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQ  68
            V+ LL LT L  +    C   CHCP   P+C+PGV LV D CGCC+VCAKQL E C++  
Sbjct  9    VIALLFLTFLRWAVAQECSGQCHCPEVPPQCSPGVSLVLDTCGCCRVCAKQLGELCTERD  68

Query  69   PCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAV  128
             CD  KGL C++G+ S    G+C A+ +G  C +   +Y++GESFQ +CK+QCTC+DGAV
Sbjct  69   VCDPHKGLYCDYGSPSNRRIGVCTAR-DGATCVFGGMVYRSGESFQSSCKYQCTCLDGAV  127

Query  129  GCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDAS  188
            GC+PLC  ++ LP+  CP PR VKV G+CCEEWVCD                ++  F  S
Sbjct  128  GCVPLCGMDIRLPSPDCPMPRRVKVPGKCCEEWVCDSP--------------RQNTFVGS  173

Query  189  EVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGIS  248
             +   R  E               +G +P ++      + C+VQTT WS CSKTCG GIS
Sbjct  174  ALAAYREEE--------------TYGPDPSMMR-----ENCLVQTTEWSACSKTCGLGIS  214

Query  249  TRVTNDNPECRLVKETRICEVRPCGQPVYSSLKK  282
            TRVTNDN ECRL K++R+C VRPC   +    KK
Sbjct  215  TRVTNDNRECRLEKQSRLCMVRPCESHLEEKKKK  248


>ref|XP_002127157.1|  PREDICTED: similar to connective tissue growth factor [Ciona 
intestinalis]
Length=374

 GENE ID: 100181891 LOC100181891 | similar to connective tissue growth factor
[Ciona intestinalis] (10 or fewer PubMed links)

 Score =  224 bits (570),  Expect = 1e-57, Method: Compositional matrix adjust.
 Identities = 134/349 (38%), Positives = 191/349 (55%), Gaps = 17/349 (5%)

Query  31   HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGI  90
            +CP   P CA GV L+   CGCCK CA+QL+E C+    CD  + L C++       +G+
Sbjct  41   NCP-PTPTCAYGVSLIPGKCGCCKQCARQLDETCNDDMKCDPHRNLYCSYSGVDEH-EGV  98

Query  91   CRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSL-PNLGCPNPR  149
            C A+  GR C  +   Y NGESF   CK +CTC+DG + C   CP  ++      C +P+
Sbjct  99   CVAK-PGRACLSSGLTYLNGESFLIGCKVKCTCMDGVLACENTCPLTITARAPKNCRHPQ  157

Query  150  LVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKR  209
            LVK   QCC EW+C  +++ +                       R   +IA+      +R
Sbjct  158  LVKKPNQCCSEWICSGETLSNNNTTNTRPSSSHSQIRRRHPNTFRP-RVIAMAAN---RR  213

Query  210  LPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEV  269
             P       I        KC VQTT WS CSKTCG G+S RVTNDN  C+L K++R+C++
Sbjct  214  TP-------ISITVRAKDKCNVQTTEWSACSKTCGWGVSERVTNDNKACKLRKQSRLCQI  266

Query  270  RPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTR  329
            RPC      ++K+GKKC +T K+   V+++++GC S K Y PKYCG+C DGRCC P+ T 
Sbjct  267  RPCSSSFVDNIKRGKKCIRTVKAQRRVQYSFSGCQS-KVYTPKYCGACTDGRCCAPKHTV  325

Query  330  TVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHK  378
            T  ++F C+ G  F K +M+I+SC C+  C   N + F + R+  D  +
Sbjct  326  TKPIKFTCDGGFQFKKRMMVIKSCSCSRRCVGEN-SFFSYRRMGGDTWQ  373


>gb|AAH93215.1|  Ctgf protein [Danio rerio]
Length=249

 GENE ID: 321449 ctgf | connective tissue growth factor [Danio rerio]
(10 or fewer PubMed links)

 Score =  219 bits (557),  Expect = 3e-56, Method: Compositional matrix adjust.
 Identities = 122/274 (45%), Positives = 162/274 (59%), Gaps = 37/274 (14%)

Query  12   VVTLLHLTRLALST---CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQ  68
            V+ LL LT L  +    C   CHCP   P+C+PGV LV D CGCC+VCAKQL E C++  
Sbjct  9    VIALLFLTFLRWAVAQECSGQCHCPEVPPQCSPGVSLVLDTCGCCRVCAKQLGELCTERD  68

Query  69   PCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAV  128
             CD  KGL C++G+ S    G+C A+ +G  C +   +Y++GESFQ +CK+Q TC+DGAV
Sbjct  69   VCDPHKGLYCDYGSPSNRRIGVCTAR-DGATCVFGGMVYRSGESFQSSCKYQWTCLDGAV  127

Query  129  GCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDAS  188
            GC+PLC  ++  P+  CP PR VKV G+CCEEWVCD          Q+  +G  L     
Sbjct  128  GCVPLCGMDIRPPSPDCPMPRRVKVPGKCCEEWVCDSPR-------QNTFVGSAL-----  175

Query  189  EVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGIS  248
                            ++ +    +G +P ++      + C+VQTT WS CSKTCG GIS
Sbjct  176  ----------------AAYREEETYGPDPSMMR-----ENCLVQTTEWSACSKTCGLGIS  214

Query  249  TRVTNDNPECRLVKETRICEVRPCGQPVYSSLKK  282
            TRVTNDN ECRL K++R+C VRPC   +    KK
Sbjct  215  TRVTNDNRECRLEKQSRLCMVRPCESHLEEKKKK  248


>gb|AAD31517.1|AF143679_1  lost in inflammatory breast cancer tumor suppressor protein [Homo 
sapiens]
 emb|CAB16556.1|  WNT1 inducible signaling pathway protein 3 [Homo sapiens]
 gb|EAW48276.1|  WNT1 inducible signaling pathway protein 3, isoform CRA_d [Homo 
sapiens]
Length=331

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score =  203 bits (516),  Expect = 2e-51, Method: Compositional matrix adjust.
 Identities = 122/337 (36%), Positives = 173/337 (51%), Gaps = 47/337 (14%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  26   CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  85

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
              + G+C  +S G  CE+N   Y NG+ FQPN    C C+ GA+GC PL           
Sbjct  86   RYETGVCACKSVG--CEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL-----------  132

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
                 + K+ G  C                  G  G +   D S   L    E +     
Sbjct  133  ----FIPKLAGSHC-----------------SGAKGGKKS-DQSNCSL----EPLLQQLS  166

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
            +S K +P +   P I       +KC+VQ T W+ CS+TCG GIS RVTN+N  C + KE 
Sbjct  167  TSYKTMPAYRNLPLIW-----KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK  221

Query  265  RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC  322
            R+C ++PC   +  ++K  KGK C  T +  +  +F ++GC S + Y+P +CG C+D RC
Sbjct  222  RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC  281

Query  323  CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC  359
            C P  ++ + ++F C +  +F   ++ I SC C  NC
Sbjct  282  CIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNC  318


>ref|NP_937882.1|  WNT1-inducible-signaling pathway protein 3 isoform 3 [Homo sapiens]
 gb|AAI05942.1|  WNT1 inducible signaling pathway protein 3 [Homo sapiens]
 gb|EAW48275.1|  WNT1 inducible signaling pathway protein 3, isoform CRA_c [Homo 
sapiens]
Length=372

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score =  200 bits (509),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 121/337 (36%), Positives = 171/337 (51%), Gaps = 46/337 (14%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  66   CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  125

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
              + G+C A      CE+N   Y NG+ FQPN    C C+ GA+GC PL           
Sbjct  126  RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL-----------  173

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
                 + K+ G  C                  G  G +   D S   L    E +     
Sbjct  174  ----FIPKLAGSHC-----------------SGAKGGKKS-DQSNCSL----EPLLQQLS  207

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
            +S K +P +   P I       +KC+VQ T W+ CS+TCG GIS RVTN+N  C + KE 
Sbjct  208  TSYKTMPAYRNLPLIW-----KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK  262

Query  265  RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC  322
            R+C ++PC   +  ++K  KGK C  T +  +  +F ++GC S + Y+P +CG C+D RC
Sbjct  263  RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC  322

Query  323  CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC  359
            C P  ++ + ++F C +  +F   ++ I SC C  NC
Sbjct  323  CIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNC  359


>gb|EAW48277.1|  WNT1 inducible signaling pathway protein 3, isoform CRA_e [Homo 
sapiens]
Length=335

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score =  200 bits (508),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 121/337 (36%), Positives = 171/337 (51%), Gaps = 46/337 (14%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  29   CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  88

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
              + G+C A      CE+N   Y NG+ FQPN    C C+ GA+GC PL           
Sbjct  89   RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL-----------  136

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
                 + K+ G  C                  G  G +   D S   L    E +     
Sbjct  137  ----FIPKLAGSHC-----------------SGAKGGKKS-DQSNCSL----EPLLQQLS  170

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
            +S K +P +   P I       +KC+VQ T W+ CS+TCG GIS RVTN+N  C + KE 
Sbjct  171  TSYKTMPAYRNLPLIW-----KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK  225

Query  265  RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC  322
            R+C ++PC   +  ++K  KGK C  T +  +  +F ++GC S + Y+P +CG C+D RC
Sbjct  226  RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC  285

Query  323  CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC  359
            C P  ++ + ++F C +  +F   ++ I SC C  NC
Sbjct  286  CIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNC  322


>gb|AAQ88715.1|  WISP-3 [Homo sapiens]
Length=372

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score =  200 bits (508),  Expect = 2e-50, Method: Compositional matrix adjust.
 Identities = 121/337 (36%), Positives = 171/337 (51%), Gaps = 46/337 (14%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  66   CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  125

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
              + G+C A      CE+N   Y NG+ FQPN    C C+ GA+GC PL           
Sbjct  126  RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL-----------  173

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
                 + K+ G  C                  G  G +   D S   L    E +     
Sbjct  174  ----FIPKLAGSHC-----------------SGAKGGKKS-DQSNCSL----EPLLQQLS  207

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
            +S K +P +   P I       +KC+VQ T W+ CS+TCG GIS RVTN+N  C + KE 
Sbjct  208  TSYKTMPAYRDLPLIW-----KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK  262

Query  265  RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC  322
            R+C ++PC   +  ++K  KGK C  T +  +  +F ++GC S + Y+P +CG C+D RC
Sbjct  263  RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC  322

Query  323  CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC  359
            C P  ++ + ++F C +  +F   ++ I SC C  NC
Sbjct  323  CIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNC  359


>ref|NP_003871.1|  WNT1-inducible-signaling pathway protein 3 isoform 1 [Homo sapiens]
 sp|O95389.1|WISP3_HUMAN  RecName: Full=WNT1-inducible-signaling pathway protein 3; Short=WISP-3; 
AltName: Full=CCN family member 6; Flags: Precursor
 gb|AAC96323.1|  connective tissue growth factor related protein WISP-3 [Homo 
sapiens]
 gb|AAQ88716.1|  WISP-3 [Homo sapiens]
 emb|CAI19998.1|  WNT1 inducible signaling pathway protein 3 [Homo sapiens]
 emb|CAI42331.1|  WNT1 inducible signaling pathway protein 3 [Homo sapiens]
 gb|EAW48273.1|  WNT1 inducible signaling pathway protein 3, isoform CRA_a [Homo 
sapiens]
Length=354

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score =  199 bits (507),  Expect = 2e-50, Method: Compositional matrix adjust.
 Identities = 121/337 (36%), Positives = 171/337 (51%), Gaps = 46/337 (14%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  48   CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  107

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
              + G+C A      CE+N   Y NG+ FQPN    C C+ GA+GC PL           
Sbjct  108  RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL-----------  155

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
                 + K+ G  C                  G  G +   D S   L    E +     
Sbjct  156  ----FIPKLAGSHC-----------------SGAKGGKKS-DQSNCSL----EPLLQQLS  189

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
            +S K +P +   P I       +KC+VQ T W+ CS+TCG GIS RVTN+N  C + KE 
Sbjct  190  TSYKTMPAYRNLPLIW-----KKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEK  244

Query  265  RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC  322
            R+C ++PC   +  ++K  KGK C  T +  +  +F ++GC S + Y+P +CG C+D RC
Sbjct  245  RLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRC  304

Query  323  CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC  359
            C P  ++ + ++F C +  +F   ++ I SC C  NC
Sbjct  305  CIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNC  341


>dbj|BAG54167.1|  unnamed protein product [Homo sapiens]
Length=215

 GENE ID: 1490 CTGF | connective tissue growth factor [Homo sapiens]
(Over 100 PubMed links)

 Score =  199 bits (505),  Expect = 3e-50, Method: Compositional matrix adjust.
 Identities = 109/249 (44%), Positives = 146/249 (59%), Gaps = 38/249 (15%)

Query  131  IPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEV  190
            +PLC  ++ LP+  CP PR VK+ G+CCEEWVCDE       +DQ               
Sbjct  1    MPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEP------KDQ---------------  39

Query  191  ELTRNNELIAVGKGSSLKRLP-VFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGIST  249
                      VG   +  RL   FG +P ++        C+VQTT WS CSKTCG GIST
Sbjct  40   --------TVVGPALAAYRLEDTFGPDPTMIR-----ANCLVQTTEWSACSKTCGMGIST  86

Query  250  RVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKY  309
            RVTNDN  CRL K++R+C VRPC   +  ++K GKKC +T K  +P++F  +GC S+K Y
Sbjct  87   RVTNDNASCRLEKQSRLCMVRPCEADLEENIK-GKKCIRTPKISKPIKFELSGCTSMKTY  145

Query  310  RPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPF  369
            R K+CG C DGRCCTP  T T+ + F+C DGE   KN+M I++C C+YNCP  N+     
Sbjct  146  RAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESL  205

Query  370  Y--RLFNDI  376
            Y  +++ D+
Sbjct  206  YYRKMYGDM  214


>gb|AAH85515.1|  Cyr61 protein [Danio rerio]
Length=249

 GENE ID: 553273 cyr61 | cysteine-rich, angiogenic inducer, 61 [Danio rerio]
(10 or fewer PubMed links)

 Score =  197 bits (502),  Expect = 7e-50, Method: Compositional matrix adjust.
 Identities = 112/244 (46%), Positives = 149/244 (61%), Gaps = 15/244 (6%)

Query  42   GVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCE  101
            GV  V D CGCCKVCA+Q N+DC    PCDH KGL C+ GA     +G+CRA++ GRPCE
Sbjct  21   GVSRVWDNCGCCKVCAQQFNQDCGSDLPCDHIKGLHCHLGAGGDPQRGLCRAEAHGRPCE  80

Query  102  YNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEW  161
            ++ R+YQ+GE FQ  C+HQC+CIDG VGC+PLCP  + LP   C NPRL   TG CC+ W
Sbjct  81   FSGRVYQHGEDFQTGCEHQCSCIDGVVGCVPLCPLLVPLPGSHCTNPRLETPTGHCCQRW  140

Query  162  VCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILY  221
            VCD D   + + +++ L      ++     L  +    A  + SS    PV  +      
Sbjct  141  VCDSD---NSIREEEPLPKHTPQYNHISKLLQEHRSRPAAQEWSS---APVSEI------  188

Query  222  NPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLK  281
             P     C  QTT WS+CS +CG G+S+RVTN N +CRL++ETR+C++ PC    +  LK
Sbjct  189  -PFPSPGCFSQTTDWSECSASCGFGVSSRVTNSNAQCRLIRETRLCQITPCDATPH--LK  245

Query  282  KGKK  285
            K KK
Sbjct  246  KKKK  249


>emb|CBY30557.1|  unnamed protein product [Oikopleura dioica]
Length=372

 Score =  194 bits (492),  Expect = 1e-48, Method: Compositional matrix adjust.
 Identities = 124/358 (35%), Positives = 185/358 (52%), Gaps = 55/358 (15%)

Query  38   KCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEG  97
            +C PGV  + D C CC+ CA+QL E C K  PCDHTKGL C    S    +  C +  + 
Sbjct  51   QCKPGVAHLWDECDCCQKCARQLGEKCDKMNPCDHTKGLAC----SKKGDEFKCDSDPKL  106

Query  98   RPCEYNSRIYQNGESFQPN---CKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVT  154
            + C  +  +  +G+ F PN   C+  C C+DG +GC P C Q+   P   C NPR  +  
Sbjct  107  KKCFISGVVKSSGDEFYPNPKSCQLTCVCVDGDIGCYPTCAQK---PPKKCLNPRYEESN  163

Query  155  --GQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPV  212
                CC EW C                       +++   TR  ++     G++ +++P 
Sbjct  164  DPNACCGEWTCG----------------------SADRPQTRPLKIQKSVFGAAHRKVP-  200

Query  213  FGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPC  272
                 +I YN     KC+VQTT WS+CS+ CG G+  RVTN+N EC + KET++C+VRPC
Sbjct  201  -----KISYN--SETKCMVQTTEWSECSRNCGWGVRERVTNNNEECEMKKETKLCQVRPC  253

Query  273  GQP----VYSSLK-----KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCC  323
                   + S  K     + K C +  +  EP++F ++GC S +KYRP+YCGSC +  CC
Sbjct  254  DASHSLEIESLFKTKPRLRNKMCLEKVRVTEPIQFEFSGCRSDQKYRPRYCGSCKNDYCC  313

Query  324  TPQLTRTVKMRFRCEDG---ETFSKNVMMIQSCKCNYNCPHANEAAFPFYR-LFNDIH  377
             P  T T+ + F C++    + F+K +  I SC+C+ +C     + F   R L ND++
Sbjct  314  KPSKTETIDVDFTCDENGKKQRFTKQMDKIVSCECSNHCGDGLASLFSSIRPLSNDVY  371


>emb|CBY09585.1|  unnamed protein product [Oikopleura dioica]
Length=372

 Score =  192 bits (487),  Expect = 4e-48, Method: Compositional matrix adjust.
 Identities = 123/358 (34%), Positives = 184/358 (51%), Gaps = 55/358 (15%)

Query  38   KCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEG  97
            +C PGV  + D C CC+ CA+QL E C    PCDHTKGL C    S    +  C +  + 
Sbjct  51   QCKPGVAHLWDKCDCCQKCARQLGEKCDMMNPCDHTKGLAC----SKKGDEFKCDSDPKL  106

Query  98   RPCEYNSRIYQNGESFQPN---CKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVT  154
            + C  +  +  +G+ F PN   C+  C C+DG +GC P C Q+   P   C NPR  +  
Sbjct  107  KKCFISGVVKSSGDEFYPNPKSCQLTCVCVDGDIGCYPTCAQK---PPKKCLNPRYEESN  163

Query  155  --GQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPV  212
                CC EW C                       +++   TR  ++     G++ +++P 
Sbjct  164  DPNACCGEWTCG----------------------SADRPQTRPLKIQKSVFGAAHRKVP-  200

Query  213  FGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPC  272
                 +I YN     KC+VQTT WS+CS+ CG G+  RVTN+N EC + KET++C+VRPC
Sbjct  201  -----KISYN--SETKCMVQTTEWSECSRNCGWGVRERVTNNNEECEMKKETKLCQVRPC  253

Query  273  GQP----VYSSLK-----KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCC  323
                   + S  K     + K C +  +  EP++F ++GC S +KYRP+YCGSC +  CC
Sbjct  254  DASHSLEIESLFKTKPRLRNKMCLEKVRVTEPIQFEFSGCRSDQKYRPRYCGSCKNDYCC  313

Query  324  TPQLTRTVKMRFRCEDG---ETFSKNVMMIQSCKCNYNCPHANEAAFPFYR-LFNDIH  377
             P  T T+ + F C++    + F+K +  I SC+C+ +C     + F   R L ND++
Sbjct  314  KPSKTETIDVDFTCDENGKKQRFTKQMDKIVSCECSNHCGDGLASLFSSIRPLSNDVY  371


>ref|NP_001159703.1|  WNT1-inducible-signaling pathway protein 3 [Danio rerio]
 gb|ACX31201.1|  WNT1 inducible signaling pathway protein 3 [Danio rerio]
Length=338

 GENE ID: 794092 wisp3 | WNT1 inducible signaling pathway protein 3
[Danio rerio] (10 or fewer PubMed links)

 Score =  189 bits (479),  Expect = 4e-47, Method: Compositional matrix adjust.
 Identities = 119/355 (34%), Positives = 170/355 (48%), Gaps = 55/355 (15%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C C +  P CAPGV  + DGCGCCK CA+Q+ E C++   CD  K + C+F     
Sbjct  34   CSWPCKCGVR-PLCAPGVSSILDGCGCCKTCAQQIGESCNERDICDPHKSMYCDFSKDQP  92

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
              + GIC A   G  C+ N   Y NG++FQPN  ++CTCI G++GC P   Q+       
Sbjct  93   RYEVGIC-AYLMGVGCDLNGAHYDNGQAFQPNPLYKCTCISGSIGCTPAFIQK-------  144

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
             P   L     Q   +      S ++P   QD        +    +   +N         
Sbjct  145  -PTGMLSPAALQ--GQLPAGLKSSRNPKNQQDTTYRTMSAYRDPPLAWKKN---------  192

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
                                    C+VQTT+WS CS++CG GIS RV NDN +C + KE 
Sbjct  193  ------------------------CLVQTTAWSPCSRSCGIGISVRVNNDNSKCEMRKER  228

Query  265  RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC  322
            R+C +RPC +     LK  KGK C    ++ +  + + +GC SVKK+RP YCG C D RC
Sbjct  229  RLCLLRPCDKNTLKRLKMPKGKTCKPKFQASKAEKLSLSGCTSVKKHRPTYCGVCTDKRC  288

Query  323  CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIH  377
            C P  ++ V + F C+ G      +  I SC C   C +A++       +F+++H
Sbjct  289  CVPNKSKMVNVEFHCKGGSNVRWKMQWITSCVCQRKCSNADD-------MFSELH  336


>emb|CAI12081.1|  novel protein similar to human WNT1 inducible signaling pathway 
protein 3 (WISP3) [Danio rerio]
Length=351

 GENE ID: 794092 wisp3 | WNT1 inducible signaling pathway protein 3
[Danio rerio] (10 or fewer PubMed links)

 Score =  181 bits (458),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 119/355 (34%), Positives = 169/355 (48%), Gaps = 62/355 (17%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C C +  P CAPGV  + DGCGCCK CA+Q+ E C++   CD  K + C+F     
Sbjct  54   CSWPCKCGVR-PLCAPGVSSILDGCGCCKTCAQQIGESCNERDICDPHKSMYCDFSKDQP  112

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
              + GIC A   G  C+ N   Y NG++FQPN  ++CTCI G++               G
Sbjct  113  RYEVGIC-AYLMGVGCDLNGAHYDNGQAFQPNPLYKCTCISGSI---------------G  156

Query  145  CPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKG  204
            C    + K TG                M     L G +L          +N +       
Sbjct  157  CTPAFIQKPTG----------------MLSPAALQG-QLPAGLKSSRNPKNQQDTTYRTM  199

Query  205  SSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKET  264
            S+ K+                   C+VQTT+WS CS++CG GIS RV NDN +C + KE 
Sbjct  200  SAWKK------------------NCLVQTTAWSPCSRSCGIGISVRVNNDNSKCEMRKER  241

Query  265  RICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRC  322
            R+C +RPC +     LK  KGK C    ++ +  + + +GC SVKK+RP YCG C D RC
Sbjct  242  RLCLLRPCDKNTLKRLKMPKGKTCKPKFQASKAEKLSLSGCTSVKKHRPTYCGVCTDKRC  301

Query  323  CTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIH  377
            C P  ++ V + F C+ G      +  I SC C   C +A++       +F+++H
Sbjct  302  CVPNKSKMVNVEFHCKGGSNVRWKMQWITSCVCQRKCSNADD-------MFSELH  349


>ref|NP_003872.1|  WNT1-inducible-signaling pathway protein 2 precursor [Homo sapiens]
 sp|O76076.1|WISP2_HUMAN  RecName: Full=WNT1-inducible-signaling pathway protein 2; Short=WISP-2; 
AltName: Full=CCN family member 5; AltName: Full=Connective 
tissue growth factor-like protein; Short=CTGF-L; 
AltName: Full=Connective tissue growth factor-related protein 
58; Flags: Precursor
 gb|AAC26794.1|  connective tissue growth factor-related protein precursor [Homo 
sapiens]
 9 more sequence titles
 
gb|AAC70350.1|  connective tissue growth factor-like protein precursor [Homo 
sapiens]
 gb|AAC96322.1|  connective tissue growth factor related protein WISP-2 [Homo 
sapiens]
 emb|CAB94788.1|  WNT1 inducible signaling pathway protein 2 [Homo sapiens]
 gb|AAH17782.1|  WNT1 inducible signaling pathway protein 2 [Homo sapiens]
 gb|AAQ89274.1|  WISP-2 [Homo sapiens]
 gb|AAH64379.1|  WNT1 inducible signaling pathway protein 2 [Homo sapiens]
 gb|EAW75902.1|  WNT1 inducible signaling pathway protein 2, isoform CRA_a [Homo 
sapiens]
 gb|EAW75903.1|  WNT1 inducible signaling pathway protein 2, isoform CRA_a [Homo 
sapiens]
 dbj|BAG36581.1|  unnamed protein product [Homo sapiens]
Length=250

 GENE ID: 8839 WISP2 | WNT1 inducible signaling pathway protein 2 [Homo sapiens]
(Over 10 PubMed links)

 Score =  151 bits (381),  Expect = 9e-36, Method: Compositional matrix adjust.
 Identities = 88/232 (38%), Positives = 120/232 (52%), Gaps = 37/232 (16%)

Query  42   GVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCE  101
            GV LV DGCGCC+VCA++L E C +   CD ++GL C  GA       +C    +   CE
Sbjct  42   GVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCE  101

Query  102  YNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEW  161
             N R+Y+ GE+FQP+C  +C C DG   C+PLC +++ LP+  CP+PR V+V G+CC EW
Sbjct  102  VNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEW  161

Query  162  VCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILY  221
            VC +                                    G G   + LP  G +   L 
Sbjct  162  VCGQ------------------------------------GGGLGTQPLPAQGPQFSGLV  185

Query  222  NPL-QGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPC  272
            + L  G  C   +T+W  CS TCG G++TRV+N N  CRL  + R+C  RPC
Sbjct  186  SSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPC  237


>ref|XP_002130743.1|  PREDICTED: similar to Protein CYR61 precursor (Cysteine-rich 
angiogenic inducer 61) (Insulin-like growth factor-binding protein 
10) (3CH61) [Ciona intestinalis]
Length=219

 GENE ID: 100183909 LOC100183909 | similar to Protein CYR61 precursor
(Cysteine-rich angiogenic inducer 61) (Insulin-like growth factor-binding
protein 10) (3CH61) [Ciona intestinalis] (10 or fewer PubMed links)

 Score =  148 bits (373),  Expect = 6e-35, Method: Compositional matrix adjust.
 Identities = 73/152 (48%), Positives = 103/152 (68%), Gaps = 3/152 (2%)

Query  229  CIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSK  288
            C V T++WS CSK+CG G+S RV+NDNP C+L ++ R+C++RPC    Y   KKG+ C +
Sbjct  65   CDVHTSAWSPCSKSCGLGVSVRVSNDNPRCQLGRDMRLCQLRPCQGNRYGP-KKGRHCMR  123

Query  289  TKKSPEPVRFTYAGCLSVKKYRPKYCGSCVD-GRCCTPQLTRTVKMRFRCEDGETFSKNV  347
             K++ +    TYAGC SV+K RP+YCG C    RCCTP+ TRT+ ++F+C DG  FSK +
Sbjct  124  QKRARKRETLTYAGCTSVRKSRPRYCGGCHGPSRCCTPKSTRTISVQFQCTDGSLFSKKM  183

Query  348  MMIQSCKCNYNC-PHANEAAFPFYRLFNDIHK  378
            M+I+SC C+ NC P+        Y L ND+H+
Sbjct  184  MVIRSCSCHSNCSPNVVHREVFQYALHNDMHQ  215


>emb|CAN87754.1|  novel protein similar to vertebrate WNT1 inducible signaling 
pathway protein 1 (WISP1) [Danio rerio]
Length=308

 GENE ID: 560713 wisp1a | WNT1 inducible signaling pathway protein 1a
[Danio rerio] (10 or fewer PubMed links)


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score =  145 bits (367),  Expect = 3e-34, Method: Compositional matrix adjust.
 Identities = 66/155 (43%), Positives = 99/155 (64%), Gaps = 7/155 (5%)

Query  227  QKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKC  286
            + C+ QTTSWS CSKTCG G+S R+TN+N +C +V E+R+C +RPC   +   +K GKKC
Sbjct  157  KNCVAQTTSWSPCSKTCGRGVSLRITNNNKKCEMVNESRLCNIRPCNVDITKHIKPGKKC  216

Query  287  SKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKN  346
                ++ +P  FT +GC S   YRPKYCG C D RCC P  ++T+++ F+C +G  F+  
Sbjct  217  LNIYRAEKPQNFTISGCTSTNTYRPKYCGVCTDERCCIPYKSKTIEVDFQCPNGPGFTWQ  276

Query  347  VMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD  381
            VM I +C CN +C + N+       +F D+ ++ +
Sbjct  277  VMWINACFCNLSCKNPND-------IFTDLEQYHE  304


 Score =  133 bits (335),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 68/133 (51%), Positives = 88/133 (66%), Gaps = 3/133 (2%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP   P C PGV L+ DGC CC+ CAKQ+ E C++ + CDH +GL C++ A   
Sbjct  16   CQWPCKCPKTPPMCPPGVSLLMDGCDCCRACAKQVREACNEKENCDHHRGLYCDYSADKP  75

Query  86   AL-KGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLG  144
               KG+C A   G  CE+N  IY+NG+SFQPNCK+QC C++GA+GC+PLC  E   P + 
Sbjct  76   RYEKGVC-AFLPGTGCEHNGVIYRNGQSFQPNCKYQCLCVNGAIGCVPLC-NESQPPRVW  133

Query  145  CPNPRLVKVTGQC  157
            C NP+ VKV GQC
Sbjct  134  CQNPQRVKVHGQC  146


>gb|AAP43925.1|  WISP1tc [Homo sapiens]
 dbj|BAG63017.1|  unnamed protein product [Homo sapiens]
Length=195

 GENE ID: 8840 WISP1 | WNT1 inducible signaling pathway protein 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  139 bits (350),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 62/155 (40%), Positives = 97/155 (63%), Gaps = 7/155 (5%)

Query  227  QKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKC  286
            + CI  T+ WS CS +CG G+STR++N N +C   +E+R+C +RPC   +++ +K GKKC
Sbjct  42   RNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKC  101

Query  287  SKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKN  346
                +    + FT AGC+S + Y+PKYCG C+D RCC P  ++T+ + F+C DG  FS+ 
Sbjct  102  LAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQ  161

Query  347  VMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD  381
            V+ I +C CN +C + N+       +F D+  + D
Sbjct  162  VLWINACFCNLSCRNPND-------IFADLESYPD  189


>emb|CAM16358.1|  novel protein similar to vertebrate connective tissue growth 
factor (CTGF) [Danio rerio]
Length=163

 GENE ID: 100007759 wisp2 | WNT1 inducible signaling pathway protein 2
[Danio rerio] (10 or fewer PubMed links)

 Score =  139 bits (349),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 71/155 (46%), Positives = 94/155 (61%), Gaps = 9/155 (6%)

Query  214  GMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCG  273
            G + R++ N      CI Q++ WS CS+TCG+GIS RV+N NP C L  + R+C +RPC 
Sbjct  12   GYQTRVVSN------CIDQSSEWSACSRTCGSGISVRVSNQNPSCVLEMQMRLCMIRPC-  64

Query  274  QPVY--SSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTV  331
            QPV   S     +KC  + +S  PVR  + GC S + YRP+YCGSC D RCCTP  T T 
Sbjct  65   QPVLHRSPQWSRRKCQPSYRSATPVRLFHQGCYSTRFYRPRYCGSCTDNRCCTPYQTGTA  124

Query  332  KMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAA  366
             + FRC  G   +  VM I SC C+YNCP+++   
Sbjct  125  MVTFRCPGGRLLNHAVMTINSCICHYNCPYSSRGT  159


>ref|NP_543028.1|  WNT1-inducible-signaling pathway protein 1 isoform 2 precursor 
[Homo sapiens]
 dbj|BAB17849.1|  WISP-1 variant [Homo sapiens]
 gb|EAW92163.1|  WNT1 inducible signaling pathway protein 1, isoform CRA_b [Homo 
sapiens]
Length=280

 GENE ID: 8840 WISP1 | WNT1 inducible signaling pathway protein 1 [Homo sapiens]
(Over 10 PubMed links)


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score =  139 bits (349),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 62/155 (40%), Positives = 97/155 (63%), Gaps = 7/155 (5%)

Query  227  QKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKC  286
            + CI  T+ WS CS +CG G+STR++N N +C   +E+R+C +RPC   +++ +K GKKC
Sbjct  127  RNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKC  186

Query  287  SKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKN  346
                +    + FT AGC+S + Y+PKYCG C+D RCC P  ++T+ + F+C DG  FS+ 
Sbjct  187  LAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQ  246

Query  347  VMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD  381
            V+ I +C CN +C + N+       +F D+  + D
Sbjct  247  VLWINACFCNLSCRNPND-------IFADLESYPD  274


 Score = 59.7 bits (143),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 45/85 (53%), Gaps = 7/85 (8%)

Query  5    IARALALVVTLLHLTRLALST-------CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCA  57
            +A AL+   T +  T   L         C   C CP   P+C  GV L+ DGC CCK+CA
Sbjct  21   LATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCA  80

Query  58   KQLNEDCSKTQPCDHTKGLECNFGA  82
            +QL ++C++   CD  +GL C++  
Sbjct  81   QQLGDNCTEAAICDPHRGLYCDYSG  105


>ref|NP_001086226.1|  WNT1 inducible signaling pathway protein 2 [Xenopus laevis]
 gb|AAH74349.1|  MGC84196 protein [Xenopus laevis]
Length=221

 GENE ID: 444655 wisp2 | WNT1 inducible signaling pathway protein 2
[Xenopus laevis] (10 or fewer PubMed links)

 Score =  135 bits (340),  Expect = 5e-31, Method: Compositional matrix adjust.
 Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 10/185 (5%)

Query  1    MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQL  60
            M   I     +++    L ++    C   C C    P+C P V ++ DGCGCC++CA+QL
Sbjct  1    MDLGILNRFLVLLVYCSLPQICAQLCRTPCFCSWIPPRCPPEVPIIVDGCGCCRICARQL  60

Query  61   NEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQ  120
             E C +   CD +K L C++       +G C    +G  CEYN + Y++ E FQP+CK Q
Sbjct  61   GESCDRLYLCDESKELLCDYATGRNG-RGTCNYNYDGG-CEYNGKEYKDDEVFQPSCKFQ  118

Query  121  CTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSI--------KDPM  172
            C C+DG + C PLC + + L    CP+PR V+V G+CC EW+CDE+          KDP+
Sbjct  119  CKCMDGGITCTPLCSENVLLATPECPSPRRVEVPGRCCPEWICDEEQQSPVSNSLEKDPL  178

Query  173  EDQDG  177
              ++G
Sbjct  179  YHREG  183


>dbj|BAB78569.1|  WNT1 inducible signaling pathway protein 3 variant [Homo sapiens]
Length=230

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score =  100 bits (249),  Expect = 1e-20, Method: Compositional matrix adjust.
 Identities = 52/109 (48%), Positives = 65/109 (60%), Gaps = 2/109 (2%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  48   CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  107

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPL  133
              + G+C A      CE+N   Y NG+ FQPN    C C+ GA+GC PL
Sbjct  108  RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL  155


>gb|AAI05941.1|  WISP3 protein [Homo sapiens]
Length=237

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score =  100 bits (249),  Expect = 2e-20, Method: Compositional matrix adjust.
 Identities = 52/109 (48%), Positives = 65/109 (60%), Gaps = 2/109 (2%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  66   CHWPCKCPHQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  125

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPL  133
              + G+C A      CE+N   Y NG+ FQPN    C C+ GA+GC PL
Sbjct  126  RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL  173


>gb|EAW48274.1|  WNT1 inducible signaling pathway protein 3, isoform CRA_b [Homo 
sapiens]
Length=219

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score =  100 bits (248),  Expect = 2e-20, Method: Compositional matrix adjust.
 Identities = 52/109 (48%), Positives = 65/109 (60%), Gaps = 2/109 (2%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  48   CHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  107

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPL  133
              + G+C A      CE+N   Y NG+ FQPN    C C+ GA+GC PL
Sbjct  108  RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL  155


>gb|AAH12028.1|  WISP3 protein [Homo sapiens]
Length=219

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score = 99.8 bits (247),  Expect = 3e-20, Method: Compositional matrix adjust.
 Identities = 52/109 (48%), Positives = 65/109 (60%), Gaps = 2/109 (2%)

Query  26   CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASST  85
            C   C CP + P+C PGV LVRDGCGCCK+CAKQ  E C++   CD  KGL C++     
Sbjct  48   CHWPCKCPHQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRP  107

Query  86   ALK-GICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPL  133
              + G+C A      CE+N   Y NG+ FQPN    C C+ GA+GC PL
Sbjct  108  RYETGVC-AYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPL  155


>ref|XP_002130917.1|  PREDICTED: similar to connective tissue growth factor [Ciona 
intestinalis]
Length=207

 GENE ID: 100184755 LOC100184755 | similar to connective tissue growth factor
[Ciona intestinalis] (10 or fewer PubMed links)

 Score = 99.8 bits (247),  Expect = 3e-20, Method: Compositional matrix adjust.
 Identities = 55/133 (41%), Positives = 79/133 (59%), Gaps = 3/133 (2%)

Query  229  CIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKK-CS  287
            C V+ + WS CSK+CG G S RV      C+L +E+R+C+VRPC    + +  +GK+ C 
Sbjct  56   CKVRASPWSNCSKSCGMGSSVRVRTRG-RCKLRRESRLCQVRPCDPDHFGTRIRGKRQCI  114

Query  288  KTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDG-RCCTPQLTRTVKMRFRCEDGETFSKN  346
                S   +   Y G  SVK Y+ KYCG C D  +CCTP  TRT K+ FR ++G  F+K 
Sbjct  115  NQVSSRSRLHLEYIGSKSVKTYKMKYCGICKDSSKCCTPFKTRTKKVWFRRKNGSRFAKK  174

Query  347  VMMIQSCKCNYNC  359
            +  ++ C+C+ NC
Sbjct  175  MAFVRKCRCHTNC  187


>gb|AAB20683.1|  potential IGF binding protein [human, Peptide Partial, 78 aa, 
segment 1 of 2]
Length=78

 Score = 98.2 bits (243),  Expect = 9e-20, Method: Compositional matrix adjust.
 Identities = 42/70 (60%), Positives = 56/70 (80%), Gaps = 0/70 (0%)

Query  96   EGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTG  155
            +G PC +   +Y++GESFQ +CK+QCTC+DGAVGC+PLC  ++ LP+  CP PR VK+ G
Sbjct  1    DGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPG  60

Query  156  QCCEEWVCDE  165
            +CCEEWVCDE
Sbjct  61   KCCEEWVCDE  70


>gb|AAI02032.1|  WISP3 protein [Homo sapiens]
 emb|CAX15195.1|  WNT1 inducible signaling pathway protein 3 [Homo sapiens]
Length=130

 GENE ID: 8838 WISP3 | WNT1 inducible signaling pathway protein 3 [Homo sapiens]
(Over 10 PubMed links)

 Score = 96.3 bits (238),  Expect = 3e-19, Method: Compositional matrix adjust.
 Identities = 44/116 (38%), Positives = 70/116 (60%), Gaps = 2/116 (2%)

Query  246  GISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLK--KGKKCSKTKKSPEPVRFTYAGC  303
            GIS RVTN+N  C + KE R+C ++PC   +  ++K  KGK C  T +  +  +F ++GC
Sbjct  2    GISNRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGC  61

Query  304  LSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNC  359
             S + Y+P +CG C+D RCC P  ++ + ++F C +  +F   ++ I SC C  NC
Sbjct  62   SSTQSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNC  117


>gb|AAS21331.1|  NOV protein homolog-like protein [Oikopleura dioica]
Length=359

 Score = 92.4 bits (228),  Expect = 4e-18, Method: Compositional matrix adjust.
 Identities = 89/342 (26%), Positives = 141/342 (41%), Gaps = 89/342 (26%)

Query  39   CAPGVGLVR--DGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSE  96
            C  G GLVR  +   CC  C +Q  E CS  +PCD++ GL C    +   L        +
Sbjct  43   CPAGYGLVRLPEPLDCCLTCGRQNGEKCSVLEPCDNSVGLHCTSSGTCQPL--------Q  94

Query  97   GRPCEYN--SRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVT  154
             R C  +  S   Q G+SF  +C  +C C++                +LGC   +     
Sbjct  95   TRQCYVDNYSVPLQTGQSFWQSCDTECFCLEDG--------------SLGCRKSK-----  135

Query  155  GQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFG  214
                      +    DP   Q+G++  ++G         R        KG          
Sbjct  136  ----------DKRSPDPECIQEGII--DVGMQKKPENTVREWRPADEKKGI---------  174

Query  215  MEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQ  274
                        + C +QTT WS CS+TCG G S R++N+N +C + K+  +C++R C +
Sbjct  175  ------------KSCTIQTTKWSTCSRTCGWGFSDRLSNNNDDCIMEKQIMLCKLRNCEE  222

Query  275  PVYSSLKKGKK-----CSKTKKSPEPVR------FTYAGCLSVKKYRPKYCGSCVDGRCC  323
               SSL++G +       K KK+    R       +++GC + K Y+ ++C  C    CC
Sbjct  223  E-GSSLQRGTRRRQLPICKIKKNKVRTRRDTKKTLSFSGCRTKKPYQMRFCPQCPGTHCC  281

Query  324  TPQLT------------RTVKMRFRCEDGETFSKNVMMIQSC  353
             P +             +  K+ F C+DG  F K +M+I+ C
Sbjct  282  -PDMEPVADNNEKYKGFKVKKIHFVCDDGVKFKKKLMVIKRC  322


>emb|CBY20185.1|  unnamed protein product [Oikopleura dioica]
Length=360

 Score = 87.8 bits (216),  Expect = 1e-16, Method: Compositional matrix adjust.
 Identities = 91/365 (25%), Positives = 143/365 (39%), Gaps = 106/365 (29%)

Query  39   CAPGVGLVR--DGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSE  96
            C  G GLVR  +   CC  C +Q  E CS  +PCD++ GL C    +   L        +
Sbjct  43   CPAGYGLVRLPEPLDCCLTCGRQNGEKCSVLEPCDNSVGLHCTSSGTCQPL--------Q  94

Query  97   GRPCEYN--SRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVT  154
             R C  +  S   Q G+SF  +C  +C C++                +LGC   +     
Sbjct  95   TRQCYVDNYSVPLQTGQSFWQSCDTECFCLEDG--------------SLGCRKSK-----  135

Query  155  GQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFG  214
                      +    DP   Q+G++  ++G         R        KG          
Sbjct  136  ----------DKRSPDPECIQEGII--DVGMQKKPENTVREWRPADEKKGI---------  174

Query  215  MEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQ  274
                        + C +QTT WS CS+TCG G S R++N+N +C + K+  +C++R C +
Sbjct  175  ------------KSCTIQTTKWSTCSRTCGWGFSDRLSNNNDDCIMEKQIMLCKLRNC-E  221

Query  275  PVYSSLKKGKK----------------------CSKTKKSPEPVR------FTYAGCLSV  306
               SSL++G +                        K KK+    R       +++GC + 
Sbjct  222  EEGSSLQRGTRNLQSRRKFAYGGPRSRSRRQLPICKIKKNKVRTRRDTKKTLSFSGCRTK  281

Query  307  KKYRPKYCGSCVDGRCCTPQLT------------RTVKMRFRCEDGETFSKNVMMIQSCK  354
            K Y+ ++C  C    CC P +             +  K+ F C+DG  F K +M+I+ C 
Sbjct  282  KPYQMRFCPQCPGTHCC-PDMEPVADNNEKYKGFKVKKIHFVCDDGVKFKKKLMVIKRCV  340

Query  355  CNYNC  359
            C   C
Sbjct  341  CGPQC  345


>ref|NP_001191799.1|  WNT1-inducible-signaling pathway protein 1 isoform 4 precursor 
[Homo sapiens]
 gb|AAP43924.1|  WISP1c [Homo sapiens]
Length=122

 GENE ID: 8840 WISP1 | WNT1 inducible signaling pathway protein 1 [Homo sapiens]
(Over 10 PubMed links)

 Score = 86.7 bits (213),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 39/99 (39%), Positives = 59/99 (60%), Gaps = 7/99 (7%)

Query  283  GKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGET  342
            GKKC    +    + FT AGC+S + Y+PKYCG C+D RCC P  ++T+ + F+C DG  
Sbjct  25   GKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLG  84

Query  343  FSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD  381
            FS+ V+ I +C CN +C + N+       +F D+  + D
Sbjct  85   FSRQVLWINACFCNLSCRNPND-------IFADLESYPD  116


>ref|XP_002731449.1|  PREDICTED: connective tissue growth factor-like [Saccoglossus 
kowalevskii]
Length=972

 GENE ID: 100368823 LOC100368823 | connective tissue growth factor-like
[Saccoglossus kowalevskii]


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score = 70.9 bits (172),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 29/64 (45%), Positives = 40/64 (63%), Gaps = 0/64 (0%)

Query  100  CEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCE  159
            CE N  +Y+NGE F  +C   C C  G++ C+ +CP  L  P+  CP PRLV V G+CC+
Sbjct  265  CEVNGNVYENGERFVVDCTAYCKCDSGSIACVSMCPPTLVAPSADCPFPRLVDVHGECCQ  324

Query  160  EWVC  163
            +W C
Sbjct  325  QWEC  328


 Score = 63.9 bits (154),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 28/74 (38%), Positives = 42/74 (57%), Gaps = 0/74 (0%)

Query  93   AQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVK  152
              + G PC +  ++ QNG++ Q  C   C C  G + C PLC     +P+  CP P+LV 
Sbjct  524  GNASGGPCRFKDQLIQNGDTIQDRCVRSCRCNLGVLLCQPLCQNHPLVPSDECPVPKLVT  583

Query  153  VTGQCCEEWVCDED  166
            + GQCC+EW C+ +
Sbjct  584  IEGQCCQEWRCNAN  597


 Score = 53.5 bits (127),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 27/72 (38%), Positives = 38/72 (53%), Gaps = 0/72 (0%)

Query  100  CEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCE  159
            C + +R Y+ GE ++ +C  +C C +GAV C  LCP        GCP   LV V   CC+
Sbjct  601  CRHQNRTYRAGEEWRASCDVRCFCREGAVLCQNLCPTYSDGAPAGCPGATLVDVPETCCQ  660

Query  160  EWVCDEDSIKDP  171
            +WVC +     P
Sbjct  661  QWVCHKGVTPTP  672


 Score = 37.7 bits (86),  Expect = 0.15, Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)

Query  8   ALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKT  67
           + A V+ LL    L+   C + C   L  P    G   + DGC CC VCA Q  + C  T
Sbjct  15  SFAFVLCLLSTVVLSSDRCTSVCEECLPPPVDCLGQRQITDGCDCCVVCAGQAEQYCDNT  74

Query  68  Q-PCDHTKGLEC  78
             PCD    L C
Sbjct  75  TLPCDAEFDLIC  86


 Score = 37.0 bits (84),  Expect = 0.20, Method: Compositional matrix adjust.
 Identities = 24/73 (33%), Positives = 34/73 (47%), Gaps = 4/73 (5%)

Query  94   QSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLC--PQELSLPNLGCPNPRLV  151
            ++  R C  +    ++GE +   C   C C +G   C P C  P E+S P   CP P L 
Sbjct  185  KTHPRACLVDGISRRHGEHYFHECNATCFCYNGVEMCTPRCQSPGEMS-PGPTCPEPILA  243

Query  152  -KVTGQCCEEWVC  163
                G+CC +W C
Sbjct  244  PPPIGECCPQWTC  256


 Score = 33.1 bits (74),  Expect = 3.6, Method: Compositional matrix adjust.
 Identities = 16/63 (25%), Positives = 31/63 (49%), Gaps = 4/63 (6%)

Query  100  CEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCP----QELSLPNLGCPNPRLVKVTG  155
            C        +G+    +C  +C C++G + C+P+CP     +++ P+  CP P + K+  
Sbjct  337  CLVEETYVHDGDWVDLDCDSRCQCLNGFLTCVPMCPLPLAPDVTQPSPLCPEPFIGKLKQ  396

Query  156  QCC  158
              C
Sbjct  397  DDC  399


>emb|CAM16359.1|  novel protein similar to vertebrate connective tissue growth 
factor (CTGF) [Danio rerio]
Length=142

 GENE ID: 100007759 wisp2 | WNT1 inducible signaling pathway protein 2
[Danio rerio] (10 or fewer PubMed links)

 Score = 70.9 bits (172),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 31/63 (49%), Positives = 41/63 (65%), Gaps = 0/63 (0%)

Query  100  CEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCE  159
            CE N   YQ G+ FQP+C  QC C  G V C+P C +++ LP   CP+PR V+  G+CC+
Sbjct  80   CELNGVSYQEGQVFQPSCSLQCQCSGGGVTCVPQCREDVLLPTPDCPHPRRVQPPGKCCK  139

Query  160  EWV  162
            EWV
Sbjct  140  EWV  142


>gb|AAG22089.1|AF305691_1  connective tissue growth factor [Scyliorhinus torazame]
Length=70

 Score = 66.6 bits (161),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 28/61 (46%), Positives = 38/61 (62%), Gaps = 0/61 (0%)

Query  310  RPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPF  369
            R K+CG C DGR CTP  T T+ + F+C DG+   K +M I++C C+YNCP  N+     
Sbjct  1    RAKFCGVCTDGRGCTPHRTATLSVEFKCPDGQLMKKKMMFIKTCACHYNCPMDNDVFQSL  60

Query  370  Y  370
            Y
Sbjct  61   Y  61


>gb|AAB20682.1|  potential IGF binding protein [human, Peptide, 77 aa]
Length=77

 Score = 64.7 bits (156),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 36/76 (47%), Positives = 41/76 (54%), Gaps = 2/76 (3%)

Query  18  LTRLALSTCPAAC--HCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKG  75
           L   A   CP  C   CP   P CAPGV  V DGC CC VCA+Q  E CS  +PCD + G
Sbjct  2   LQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSG  61

Query  76  LECNFGASSTALKGIC  91
           L C+  A  +   GIC
Sbjct  62  LYCDRSADPSNQTGIC  77


>ref|NP_001191798.1|  WNT1-inducible-signaling pathway protein 1 isoform 3 precursor 
[Homo sapiens]
Length=155

 GENE ID: 8840 WISP1 | WNT1 inducible signaling pathway protein 1 [Homo sapiens]
(Over 10 PubMed links)

 Score = 60.1 bits (144),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 8/112 (7%)

Query  5    IARALALVVTLLHLTRLALST-------CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCA  57
            +A AL+   T +  T   L         C   C CP   P+C  GV L+ DGC CCK+CA
Sbjct  21   LATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCA  80

Query  58   KQLNEDCSKTQPCDHTKGLECNF-GASSTALKGICRAQSEGRPCEYNSRIYQ  108
            +QL ++C++   CD  +GL C++ G       G+C  + E   C     I++
Sbjct  81   QQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCARREEVSGCVPARGIHE  132


>gb|AAP43926.1|  WISP1i [Homo sapiens]
Length=163

 GENE ID: 8840 WISP1 | WNT1 inducible signaling pathway protein 1 [Homo sapiens]
(Over 10 PubMed links)

 Score = 59.3 bits (142),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 8/112 (7%)

Query  5    IARALALVVTLLHLTRLALST-------CPAACHCPLEAPKCAPGVGLVRDGCGCCKVCA  57
            +A AL+   T +  T   L         C   C CP   P+C  GV L+ DGC CCK+CA
Sbjct  21   LATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCA  80

Query  58   KQLNEDCSKTQPCDHTKGLECNF-GASSTALKGICRAQSEGRPCEYNSRIYQ  108
            +QL ++C++   CD  +GL C++ G       G+C  + E   C     I++
Sbjct  81   QQLGDNCTEAVICDPHRGLYCDYSGDRPRYAIGVCARREEVSGCVPARGIHE  132


>ref|XP_001195948.1|  PREDICTED: similar to Kielin, partial [Strongylocentrotus purpuratus]
 ref|XP_792448.2|  PREDICTED: similar to Kielin, partial [Strongylocentrotus purpuratus]
Length=3857

 GENE ID: 587640 LOC587640 | similar to Kielin [Strongylocentrotus purpuratus]


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score = 50.4 bits (119),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 35/84 (42%), Positives = 45/84 (54%), Gaps = 9/84 (11%)

Query  76    LECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCP  135
             LEC     + A+KG C A  EG  C +  R+Y NGE+F+P+   QC C++G V CI    
Sbjct  3147  LECPASRCTHAVKGSCCAICEG--CLFEERLYNNGENFRPDDCRQCNCVNGNVLCI----  3200

Query  136   QELSLPNLGCPNPRLVKVTGQCCE  159
              E   P L C N    +  GQCCE
Sbjct  3201  -EQECPVLTCEN--QARDIGQCCE  3221


 Score = 34.7 bits (78),  Expect = 1.0, Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 31/61 (51%), Gaps = 9/61 (15%)

Query  100   CEYNSRIYQNGESF--QPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQC  157
             C + + +  NG+SF    +    C C++G V C     Q ++ P L CPNP   K  GQC
Sbjct  3053  CSFENLLLSNGQSFGHPADVCQSCLCVNGNVDC-----QTVNCPTLTCPNPE--KAEGQC  3105

Query  158   C  158
             C
Sbjct  3106  C  3106


 Score = 32.0 bits (71),  Expect = 6.8, Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 7/59 (12%)

Query  100   CEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCC  158
             C+Y  R   NGE+F  +    CTC  G+V C P     L  P L C   +    TG+CC
Sbjct  1705  CDYEGRRLSNGETFSGDVCSSCTCSYGSVTCEP-----LRCPTLSC--LQQTTPTGECC  1756


>ref|XP_002124295.1|  PREDICTED: similar to Kielin [Ciona intestinalis]
Length=1993

 GENE ID: 100176471 LOC100176471 | similar to Kielin [Ciona intestinalis]


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score = 48.5 bits (114),  Expect = 9e-05, Method: Compositional matrix adjust.
 Identities = 30/75 (40%), Positives = 44/75 (59%), Gaps = 11/75 (15%)

Query  100  CEYNSRIYQNGESFQPNCK--HQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQC  157
            C Y  ++Y+NGE+F PN    + CTC++  V C      E S PN+ CPNP  + V+GQC
Sbjct  11   CSYQRQLYRNGETFHPNNDLCYTCTCLNNDVKC-----SEPSCPNIDCPNP--IHVSGQC  63

Query  158  CEEWVCDEDSIKDPM  172
            C +  C+E S  + +
Sbjct  64   CPQ--CNECSYNNQI  76


 Score = 33.9 bits (76),  Expect = 1.7, Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 31/66 (47%), Gaps = 4/66 (6%)

Query  70    CDHTKGLECNFGASST----ALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCID  125
             CD+   ++C   A  T    ++  + R       C Y ++ + N E FQPN   +C C D
Sbjct  1229  CDNLGAVQCTSPACDTECTHSVPSLQRCCGTCNDCFYQNQTWSNKERFQPNSCQECVCTD  1288

Query  126   GAVGCI  131
             G V C+
Sbjct  1289  GNVHCV  1294


>gb|AAH58074.1|  WISP2 protein [Homo sapiens]
 emb|CAH73886.1|  WNT1 inducible signaling pathway protein 2 [Homo sapiens]
Length=218

 GENE ID: 8839 WISP2 | WNT1 inducible signaling pathway protein 2 [Homo sapiens]
(Over 10 PubMed links)

 Score = 48.1 bits (113),  Expect = 9e-05, Method: Compositional matrix adjust.
 Identities = 24/50 (48%), Positives = 31/50 (62%), Gaps = 0/50 (0%)

Query  42  GVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGIC  91
           GV LV DGCGCC+VCA++L E C +   CD ++GL C  GA       +C
Sbjct  42  GVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALC  91


>ref|XP_002122650.1|  PREDICTED: similar to HyTSR1 protein [Ciona intestinalis]
Length=1108

 GENE ID: 100187312 LOC100187312 | similar to HyTSR1 protein
[Ciona intestinalis]


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score = 43.1 bits (100),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 26/77 (34%), Positives = 35/77 (45%), Gaps = 8/77 (10%)

Query  230  IVQTTSWSQCSKTCGTGISTRVTN-------DNPECRLVKETRICEVRPCGQP-VYSSLK  281
            I   T W  CSKTCG G S R  N         P C  +++T++C +R C  P + S   
Sbjct  369  ISDWTGWGMCSKTCGAGESIRTRNITQNAAHGAPSCPALQQTKVCNIRKCPVPCIVSDWN  428

Query  282  KGKKCSKTKKSPEPVRF  298
                CSK+    E +R 
Sbjct  429  DWSACSKSCGDGESIRI  445


 Score = 39.3 bits (90),  Expect = 0.048, Method: Compositional matrix adjust.
 Identities = 28/72 (39%), Positives = 35/72 (49%), Gaps = 13/72 (18%)

Query  229  CIVQ-TTSWSQCSKTCGTGISTRVTN-------DNPECRLVKETRICEVRPCGQPV---Y  277
            CIV     WS CSK+CG G S R+ N         P C +++E+  C +RPC  PV    
Sbjct  422  CIVSDWNDWSACSKSCGDGESIRIRNITRHPAHGAPSCPVLRESNPCHIRPC--PVACAV  479

Query  278  SSLKKGKKCSKT  289
            S       CSKT
Sbjct  480  SGWTAWDACSKT  491


 Score = 37.7 bits (86),  Expect = 0.15, Method: Compositional matrix adjust.
 Identities = 23/70 (33%), Positives = 34/70 (49%), Gaps = 8/70 (11%)

Query  236  WSQCSKTCGTGISTRVTN-------DNPECRLVKETRICEVRPCGQP-VYSSLKKGKKCS  287
            WS CSK+CG G++ R  N         P C  +++ + C +R C  P + S       CS
Sbjct  320  WSACSKSCGVGVAIRSRNITRHPAHGAPSCPALQQNKTCNLRTCPVPCLISDWTGWGMCS  379

Query  288  KTKKSPEPVR  297
            KT  + E +R
Sbjct  380  KTCGAGESIR  389


 Score = 36.2 bits (82),  Expect = 0.38, Method: Compositional matrix adjust.
 Identities = 24/71 (34%), Positives = 35/71 (49%), Gaps = 8/71 (11%)

Query  235  SWSQCSKTCGTG--ISTRVTNDNPE-----CRLVKETRICEVRPCGQP-VYSSLKKGKKC  286
            SW  CSKTCG G  + TR    +P      C  ++E++ C +R C  P + S       C
Sbjct  99   SWGTCSKTCGAGQTLRTRTITRHPAHGGSACPTLRESKACNIRTCPVPCLVSGWASWGTC  158

Query  287  SKTKKSPEPVR  297
            SKT  + + +R
Sbjct  159  SKTCGAGQTIR  169


 Score = 36.2 bits (82),  Expect = 0.43, Method: Compositional matrix adjust.
 Identities = 23/70 (33%), Positives = 34/70 (49%), Gaps = 9/70 (13%)

Query  229  CIVQT-TSWSQCSKTCGTGISTRVTN-------DNPECRLVKETRICEVRPCGQP-VYSS  279
            C+V   T W  CSKTCG G + R  N           C  +++ ++C+VR C  P + S 
Sbjct  257  CLVSIWTGWDTCSKTCGEGETIRTRNITRPSAHGGASCPALRQAKVCDVRKCPVPCLVSD  316

Query  280  LKKGKKCSKT  289
             +    CSK+
Sbjct  317  WQHWSACSKS  326


 Score = 35.8 bits (81),  Expect = 0.50, Method: Compositional matrix adjust.
 Identities = 24/71 (34%), Positives = 35/71 (49%), Gaps = 8/71 (11%)

Query  235  SWSQCSKTCGTG--ISTRVTNDNP-----ECRLVKETRICEVRPCGQP-VYSSLKKGKKC  286
            SW  CSKTCG G  I TR    +P      C  ++E++ C +R C  P + S       C
Sbjct  154  SWGTCSKTCGAGQTIRTRTITRHPAHGGSACPTLRESKACNIRTCPVPCLVSGWASWGTC  213

Query  287  SKTKKSPEPVR  297
            S+T  + + +R
Sbjct  214  SETCGAGQTIR  224


 Score = 34.7 bits (78),  Expect = 1.1, Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 34/71 (48%), Gaps = 8/71 (11%)

Query  235  SWSQCSKTCGTG--ISTRVTNDNPE-----CRLVKETRICEVRPCGQPVYSSLKKG-KKC  286
            SW  CS+TCG G  I TR    +P      C  ++E++ C +R C      S+  G   C
Sbjct  209  SWGTCSETCGAGQTIRTRTITRHPAHGGSACPTLRESKACNIRTCPVSCLVSIWTGWDTC  268

Query  287  SKTKKSPEPVR  297
            SKT    E +R
Sbjct  269  SKTCGEGETIR  279


 Score = 33.5 bits (75),  Expect = 2.3, Method: Compositional matrix adjust.
 Identities = 22/76 (29%), Positives = 35/76 (46%), Gaps = 8/76 (11%)

Query  230  IVQTTSWSQCSKTCGTGISTRV-------TNDNPECRLVKETRICEVRPCGQP-VYSSLK  281
            +   TSW+ CSK+CG G S R         +    C  +++T+ C    C  P ++S   
Sbjct  39   VSAWTSWNGCSKSCGGGQSVRTRTITRNRAHGGHACPALRQTKACNTHKCPVPCLFSGWA  98

Query  282  KGKKCSKTKKSPEPVR  297
                CSKT  + + +R
Sbjct  99   SWGTCSKTCGAGQTLR  114


>ref|XP_002599939.1|  hypothetical protein BRAFLDRAFT_74063 [Branchiostoma floridae]
 gb|EEN55951.1|  hypothetical protein BRAFLDRAFT_74063 [Branchiostoma floridae]
Length=3055

 GENE ID: 7235194 BRAFLDRAFT_74063 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score = 42.7 bits (99),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 8/78 (10%)

Query  100   CEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCE  159
             C +  ++Y NG++F P+   +C+C +G V CI       S P L CP  + V+  G CC+
Sbjct  2372  CSFEGQVYNNGQAFNPDACRECSCANGNVQCI-----SQSCPPLSCPPNQQVQEPGACCK  2426

Query  160   EWVCDEDSIKDPMEDQDG  177
             + +       D  + QDG
Sbjct  2427  KCL---GCFHDGQQYQDG  2441


 Score = 37.7 bits (86),  Expect = 0.12, Method: Compositional matrix adjust.
 Identities = 30/81 (37%), Positives = 41/81 (51%), Gaps = 11/81 (14%)

Query  82    ASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCK--HQCTCIDGAVGCIPLCPQELS  139
             A++ ++ G C     G  C YN+R YQ GE+F PN     QCTC DG + C+       S
Sbjct  2473  ANTMSVPGQCCPVCSG--CMYNNRTYQEGETFNPNGDPCDQCTCEDGNMRCL-----RYS  2525

Query  140   LPNLGCPNPRLVK--VTGQCC  158
               NL    P L++    G+CC
Sbjct  2526  CENLDSCPPTLIRDPRPGECC  2546


 Score = 34.7 bits (78),  Expect = 1.0, Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 23/93 (25%)

Query  70    CDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQP--NCKHQCTCIDGA  127
             CDH +G++           G C  + EG  C Y    Y+NGE+F P  +   +C C +G 
Sbjct  2239  CDHPEGID-----------GCC-PRCEG--CRYEQTNYRNGETFSPVGDPCEECICTEGT  2284

Query  128   VGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEE  160
             V C          P   CPNP  +   GQCC E
Sbjct  2285  VNC-----GRTICPRAACPNP--ITQPGQCCPE  2310


 Score = 32.0 bits (71),  Expect = 8.3, Method: Compositional matrix adjust.
 Identities = 25/63 (40%), Positives = 32/63 (51%), Gaps = 9/63 (14%)

Query  100   CEYNSRIYQNGESF-QPNCK-HQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQC  157
             C Y  + Y+NG  F  P  +   C+C +G V CI         P L CPNP  V+V G+C
Sbjct  1895  CTYQGQQYRNGAEFAHPTDRCRVCSCRNGNVMCI-----RRPCPPLECPNP--VRVPGKC  1947

Query  158   CEE  160
             C E
Sbjct  1948  CPE  1950


>ref|NP_001158471.1|  neuralin [Saccoglossus kowalevskii]
 gb|ACH68445.1|  neuralin protein [Saccoglossus kowalevskii]
Length=478

 GENE ID: 100303563 nrln | neuralin [Saccoglossus kowalevskii]


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score = 40.4 bits (93),  Expect = 0.021, Method: Compositional matrix adjust.
 Identities = 35/97 (36%), Positives = 47/97 (48%), Gaps = 15/97 (15%)

Query  95   SEGRPCEYNSRIYQNGESFQP--------NCKHQCTCIDGAVGCIPL-CPQELSLPNLGC  145
            S+GR C  N +IY++G+S+ P        NC   CTC +    C  L CP++     L C
Sbjct  244  SDGRECLSNGQIYEHGKSWNPYLFPFGKMNCI-ICTCRNTKTKCERLTCPED---HELAC  299

Query  146  PNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKE  182
             NP  V + GQCC+    D D      ED   LL +E
Sbjct  300  DNP--VNILGQCCKSCPGDSDGAVMVTEDDTCLLDRE  334


 Score = 39.7 bits (91),  Expect = 0.037, Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 39/80 (49%), Gaps = 16/80 (20%)

Query  94   QSEGRPCEYNSRIYQNGESFQPNCK-------HQCTCIDGAVGCIPLCPQELSLPNLGCP  146
            Q+E   C +    Y +GES+ P  +         CTC +G V C+      +  P L CP
Sbjct  24   QNEKDSCSFGDLGYSSGESWHPYLQPIGYLYCITCTCREGLVNCM-----NIKCPALSCP  78

Query  147  NPRLVKVTGQCCEEWVCDED  166
            NP  V V GQCC++  C ED
Sbjct  79   NP--VSVPGQCCKQ--CSED  94


>ref|XP_002124369.1|  PREDICTED: similar to predicted protein [Ciona intestinalis]
Length=2841

 GENE ID: 100186692 LOC100186692 | similar to predicted protein
[Ciona intestinalis]


                                                         Sort alignments for this subject sequence by:
                                                           E value  Score  Percent identity
                                                           Query start position  Subject start position
 Score = 40.4 bits (93),  Expect = 0.023, Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 5/61 (8%)

Query  98    RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQC  157
             + CEY   +Y+NG+ F+PN    C C+ G+V C  +     + P + C NP  V   G C
Sbjct  2524  QDCEYEGEVYRNGQQFEPNDCENCVCVSGSVTCRSV---ATNCPQVTCINP--VMKPGDC  2578

Query  158   C  158
             C
Sbjct  2579  C  2579


 Score = 37.7 bits (86),  Expect = 0.14, Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 34/67 (51%), Gaps = 9/67 (13%)

Query  98    RPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQC  157
             R C +N R+ +NG++F  +   QCTC  G V C+         P+L C N R +   G C
Sbjct  2637  RDCSFNGRVLRNGQNFMNDSCSQCTCAFGNVECVT-----QQCPSLSCINKRTIP--GSC  2689

Query  158   CEEWVCD  164
             C   VCD
Sbjct  2690  CP--VCD  2694


>gb|AAB20684.1|  potential IGF binding protein [human, Peptide Partial, 22 aa, 
segment 2 of 2]
Length=22

 Score = 39.7 bits (91),  Expect = 0.034, Method: Composition-based stats.
 Identities = 19/22 (86%), Positives = 19/22 (86%), Gaps = 0/22 (0%)

Query  234  TSWSQCSKTCGTGISTRVTNDN  255
            T WS CSKTCG GISTRVTNDN
Sbjct  1    TEWSACSKTCGMGISTRVTNDN  22


>emb|CAX13292.1|  novel protein similar to H.sapiens HTRA3, HtrA serine peptidase 
3 (HTRA3, zgc:91963) [Danio rerio]
Length=382

 GENE ID: 445108 zgc:91963 | zgc:91963 [Danio rerio] (10 or fewer PubMed links)

 Score = 39.3 bits (90),  Expect = 0.045, Method: Compositional matrix adjust.
 Identities = 33/108 (31%), Positives = 46/108 (43%), Gaps = 11/108 (10%)

Query  9    LALVVTLLHLTRLAL----STCPAACH---CPLEAPKCAPGVGLVRDGCGCCKVCAKQLN  61
            L    T +    LA+    S CP+ C    CP  +P C  G   V D C CC VC+    
Sbjct  5    LLAAATFIFTQDLAIAELKSNCPSKCDVSKCP--SPSCPSG--YVPDRCNCCLVCSLGEG  60

Query  62   EDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQN  109
              C + +      GLEC F       KG+C+ ++  R C  + + Y N
Sbjct  61   APCGRKEDVLCGDGLECKFPTGKRLSKGVCQCKTIHRVCGTDGKTYGN  108


>gb|AAI70476.1|  Slit2-a protein [Xenopus laevis]
 gb|AAI70478.1|  Slit2-a protein [Xenopus laevis]
Length=1530

 GENE ID: 394404 slit2 | slit homolog 2 [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 39.3 bits (90),  Expect = 0.050, Method: Compositional matrix adjust.
 Identities = 21/57 (37%), Positives = 28/57 (49%), Gaps = 1/57 (2%)

Query  300   YAGCLSVKKYRPKYC-GSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKC  355
             YA C + +K     C G C +G+CC P  ++  K  F C DG +F   V  I  C C
Sbjct  1469  YAACQTTEKVSRLECKGGCSNGQCCGPLRSKRRKYAFECTDGSSFVDEVEKIIKCGC  1525


>ref|NP_001081137.1|  slit homolog 2 [Xenopus laevis]
 gb|AAL02123.1|  Slit [Xenopus laevis]
Length=1530

 GENE ID: 394404 slit2 | slit homolog 2 [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 38.9 bits (89),  Expect = 0.053, Method: Compositional matrix adjust.
 Identities = 21/57 (37%), Positives = 28/57 (49%), Gaps = 1/57 (2%)

Query  300   YAGCLSVKKYRPKYC-GSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKC  355
             YA C + +K     C G C +G+CC P  ++  K  F C DG +F   V  I  C C
Sbjct  1469  YAACQTTEKVSRLECKGGCSNGQCCGPLRSKRRKYAFECTDGSSFVDEVEKIIKCGC  1525


>ref|NP_571810.1|  slit homolog 2 protein [Danio rerio]
 gb|AAG36773.1|  Slit2 [Danio rerio]
 emb|CAP71962.1|  slit2 [Danio rerio]
Length=1512

 GENE ID: 80353 slit2 | slit (Drosophila) homolog 2 [Danio rerio]
(Over 10 PubMed links)

 Score = 38.9 bits (89),  Expect = 0.056, Method: Compositional matrix adjust.
 Identities = 23/58 (40%), Positives = 30/58 (52%), Gaps = 2/58 (3%)

Query  300   YAGCLSVKKYRPKYC-GSCVDG-RCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKC  355
             YA C S +K     C GSC DG  CC P  ++  K  F+C DG +F + V  +  C C
Sbjct  1450  YAACQSTEKVSRLECRGSCGDGTSCCAPLRSKRRKYTFQCTDGSSFVQEVEKVVKCGC  1507


>ref|NP_001003502.1|  hypothetical protein LOC445108 [Danio rerio]
 gb|AAH78402.1|  Zgc:91963 [Danio rerio]
Length=489

 GENE ID: 445108 zgc:91963 | zgc:91963 [Danio rerio] (10 or fewer PubMed links)

 Score = 38.9 bits (89),  Expect = 0.058, Method: Compositional matrix adjust.
 Identities = 33/108 (31%), Positives = 46/108 (43%), Gaps = 11/108 (10%)

Query  9    LALVVTLLHLTRLAL----STCPAACH---CPLEAPKCAPGVGLVRDGCGCCKVCAKQLN  61
            L    T +    LA+    S CP+ C    CP  +P C  G   V D C CC VC+    
Sbjct  5    LLAAATFIFTQDLAIAELKSNCPSKCDVSKCP--SPSCPSG--YVPDRCNCCLVCSLGEG  60

Query  62   EDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQN  109
              C + +      GLEC F       KG+C+ ++  R C  + + Y N
Sbjct  61   APCGRKEDVLCGDGLECKFPTGKRLSKGVCQCKTIHRVCGTDGKTYGN  108


>ref|XP_003120782.1|  PREDICTED: mucin-19-like [Homo sapiens]
Length=6961

 GENE ID: 100506072 LOC100506072 | mucin-19-like [Homo sapiens]

 Score = 38.9 bits (89),  Expect = 0.065, Method: Composition-based stats.
 Identities = 29/88 (33%), Positives = 36/88 (41%), Gaps = 7/88 (8%)

Query  54   KVCAKQLNEDCSKTQPCDHTK---GLECNFG--ASSTALKGICRAQSEGRPCEYNSRIYQ  108
            K C       CS   P   ++   G  C  G        KG C  ++E  PCE +  +YQ
Sbjct  144  KECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAEC-PCESSGTVYQ  202

Query  109  NGESFQPNCKHQCTCIDGAVGCI-PLCP  135
             GE  +  C  QCTC D    C   LCP
Sbjct  203  PGEVREGPCGSQCTCQDAKWSCTEALCP  230