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Alignment Text XML ASN.1 Hit Table(text) Hit Table(csv)	Search Strategies ASN.1	Bioseq ASN.1	PSSM Text	PssmWithParameters ASN.1	[?]
sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase...

Query ID: lcl|9149
Description: sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase 1 OS=Homo sapiens GN=PTGS1 PE=1 SV=1
Molecule type: amino acid
Query Length: 599
Database Name: swissprot
Description: Non-redundant SwissProt sequences See details
Program: BLASTP 2.2.19+ Citation
Other reports: Search Summary [Distance tree of results]
Search Parameters
Program	blastp
Word size	3
Expect value	10
Hitlist size	100
Gapcosts	11,1
Matrix	BLOSUM62
Threshold	11
Composition-based stats	2
Low Complexity Filter	Yes
Filter string	L;
Genetic Code	1
Window Size	40
Database
Posted date	Feb 8, 2009 5:55 PM
Number of letters	134,540,208
Number of sequences	358,519
Entrez query	none
Karlin-Altschul statistics
Params	Ungapped	Gapped
Lambda	0.321898	0.267
K	0.140185	0.041
H	0.44714	0.14
Results Statistics
Length adjustment	121
Effective length of query	478
Effective length of database	91159409
Effective search space	43574197502
Effective search space used	43574197502
Alignments Select All Get selected sequences

>sp|P23219.1|PGH1_HUMAN  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=599

 GENE ID: 5742 PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxygenase) [Homo sapiens] (Over 100 PubMed links)

 Score = 1141 bits (2952),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 576/576 (100%), Positives = 576/576 (100%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP
Sbjct  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN
Sbjct  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQH
Sbjct  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQH  203

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP
Sbjct  204  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG
Sbjct  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL
Sbjct  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI
Sbjct  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY
Sbjct  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL
Sbjct  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
Sbjct  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599


>sp|P05979.2|PGH1_SHEEP  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=600

 GENE ID: 443551 PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin
G/H synthase and cyclooxygenase) [Ovis aries] (Over 10 PubMed links)

 Score = 1072 bits (2771),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 534/576 (92%), Positives = 554/576 (96%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPGAP PVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP +WTWLR +LRP
Sbjct  25   ADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPEIWTWLRTTLRP  84

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSF HF+LTHGRW W+FVNATFIR+ LMRLVLTVRSNLIPSPPTYN AHDYISWESFSN
Sbjct  85   SPSFIHFMLTHGRWLWDFVNATFIRDTLMRLVLTVRSNLIPSPPTYNIAHDYISWESFSN  144

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVP+DCPTPMGTKGKKQLPDA+ L+RRFLLRRKFIPDPQGTNLMFAFFAQH
Sbjct  145  VSYYTRILPSVPRDCPTPMGTKGKKQLPDAEFLSRRFLLRRKFIPDPQGTNLMFAFFAQH  204

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQ+L+GE+YPP
Sbjct  205  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPP  264

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT+WLREHNRVCDLLKAEHPTWG
Sbjct  265  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATIWLREHNRVCDLLKAEHPTWG  324

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQT RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFG QFQYRNRIAMEFN L
Sbjct  325  DEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQL  384

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF+VG Q+YSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN+DHHI
Sbjct  385  YHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHI  444

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAVDVI+ESR +RLQPFNEYRKRFGMKPYTSFQEL GEKEMAAELEELYGDIDALEFY
Sbjct  445  LHVAVDVIKESRVLRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFY  504

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKCHPNSIFGESMIE+GAPFSLKGLLGNPICSPEYWK STFGGEVGFN+VKTATL
Sbjct  505  PGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGEVGFNLVKTATL  564

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSF VPD  Q+D P VERP TEL
Sbjct  565  KKLVCLNTKTCPYVSFHVPDPRQEDRPGVERPPTEL  600


>sp|O62664.2|PGH1_BOVIN  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=600

 GENE ID: 282022 PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin
G/H synthase and cyclooxygenase) [Bos taurus] (10 or fewer PubMed links)

 Score = 1068 bits (2762),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 532/576 (92%), Positives = 554/576 (96%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPGAP PVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGY GPNCTIP +WTWLR +LRP
Sbjct  25   ADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYYGPNCTIPEIWTWLRTTLRP  84

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSF HFLLTHGRW W+FVNATFIR+ LMRLVLTVRSNLIPSPPTYN AHDYISWESFSN
Sbjct  85   SPSFVHFLLTHGRWLWDFVNATFIRDKLMRLVLTVRSNLIPSPPTYNVAHDYISWESFSN  144

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVP+DCPTPMGTKGKKQLPDA+ L+RRFLLRRKFIPDPQGTNLMFAFFAQH
Sbjct  145  VSYYTRILPSVPRDCPTPMGTKGKKQLPDAEFLSRRFLLRRKFIPDPQGTNLMFAFFAQH  204

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQ+L+GE+YPP
Sbjct  205  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPP  264

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLM+YAT+WLREHNRVCDLLKAEHPTWG
Sbjct  265  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMVYATIWLREHNRVCDLLKAEHPTWG  324

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQT RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFG QFQYRNRIAMEFN L
Sbjct  325  DEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQL  384

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF+VG Q+YSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN+DHHI
Sbjct  385  YHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHI  444

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAVDVI+ESRE+RLQPFNEYRKRFGMKPYTSFQEL GEKEMAAELEELYGDIDALEFY
Sbjct  445  LHVAVDVIKESRELRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFY  504

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKCHPNSIFGESMIE+GAPFSLKGLLGNPICSPEYWK STFGG+VGFN+VKTATL
Sbjct  505  PGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGDVGFNLVKTATL  564

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSF VPD  ++D P VERP TEL
Sbjct  565  KKLVCLNTKTCPYVSFHVPDPHREDRPGVERPPTEL  600


>sp|O97554.1|PGH1_RABIT  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=606

 GENE ID: 100009407 COX-1 | cyclooxygenase-1 [Oryctolagus cuniculus]

 Score = 1063 bits (2748),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 527/576 (91%), Positives = 552/576 (95%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPGAP PVNPCCY+PCQHQG+CVR  LDRYQCDCTRTGYSGPNCT+P LWTWLR+SLRP
Sbjct  31   ADPGAPAPVNPCCYFPCQHQGVCVRVALDRYQCDCTRTGYSGPNCTVPDLWTWLRSSLRP  90

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SP+F H+LLTH RWFWEFVNATFIR+ LMRLVLTVRSNLIPSPPTYN  +DYISWE+FSN
Sbjct  91   SPTFVHYLLTHVRWFWEFVNATFIRDTLMRLVLTVRSNLIPSPPTYNLDYDYISWEAFSN  150

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTR+LPSVPKDCPTPMGTKGKKQLPDAQ+LA RFLLRR FIPDPQGTNLMFAFFAQH
Sbjct  151  VSYYTRVLPSVPKDCPTPMGTKGKKQLPDAQVLAHRFLLRRTFIPDPQGTNLMFAFFAQH  210

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGD+LERQY LRLFKDGKLKYQVLDGE+YPP
Sbjct  211  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDSLERQYHLRLFKDGKLKYQVLDGEVYPP  270

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVEEAPVLMHYPRG+PP+SQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTW 
Sbjct  271  SVEEAPVLMHYPRGVPPRSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWD  330

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPE+LF VQFQYRNRIAMEFNHL
Sbjct  331  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPEMLFSVQFQYRNRIAMEFNHL  390

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF+VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN+DHH+
Sbjct  391  YHWHPLMPDSFQVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQSAGRIGGGRNIDHHV  450

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAV+VI+ESREMRLQPFNEYRKRFG+KPY SFQEL GE EMAAELEELYGDIDALEFY
Sbjct  451  LHVAVEVIKESREMRLQPFNEYRKRFGLKPYASFQELTGETEMAAELEELYGDIDALEFY  510

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKC PNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVG N++KTATL
Sbjct  511  PGLLLEKCQPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGSNLIKTATL  570

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSFRVP +S DDGPA ER STEL
Sbjct  571  KKLVCLNTKTCPYVSFRVPRSSGDDGPAAERRSTEL  606


>sp|P22437.1|PGH1_MOUSE  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=602

 GENE ID: 19224 Ptgs1 | prostaglandin-endoperoxide synthase 1 [Mus musculus]
(Over 100 PubMed links)

 Score = 1038 bits (2684),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 518/576 (89%), Positives = 546/576 (94%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPG P+PVNPCCYYPCQ+QG+CVRFGLD YQCDCTRTGYSGPNCTIP +WTWLRNSLRP
Sbjct  27   ADPGVPSPVNPCCYYPCQNQGVCVRFGLDNYQCDCTRTGYSGPNCTIPEIWTWLRNSLRP  86

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSFTHFLLTHG W WEFVNATFIRE+LMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN
Sbjct  87   SPSFTHFLLTHGYWLWEFVNATFIREVLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  146

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVPKDCPTPMGTKGKKQLPD QLLA++ LLRR+FIP PQGTN++FAFFAQH
Sbjct  147  VSYYTRILPSVPKDCPTPMGTKGKKQLPDVQLLAQQLLLRREFIPAPQGTNILFAFFAQH  206

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQY LRLFKDGKLKYQVLDGE+YPP
Sbjct  207  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYHLRLFKDGKLKYQVLDGEVYPP  266

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVE+A VLM YP G+PP+ QMAVGQEVFGLLPGLML++T+WLREHNRVCDLLK EHPTW 
Sbjct  267  SVEQASVLMRYPPGVPPERQMAVGQEVFGLLPGLMLFSTIWLREHNRVCDLLKEEHPTWD  326

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLILIGETIKIVIEEYVQ LSGYFLQLKFDPELLF  QFQYRNRIAMEFNHL
Sbjct  327  DEQLFQTTRLILIGETIKIVIEEYVQHLSGYFLQLKFDPELLFRAQFQYRNRIAMEFNHL  386

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMP+SF+VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN D+H+
Sbjct  387  YHWHPLMPNSFQVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQRAGRIGGGRNFDYHV  446

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAVDVI+ESREMRLQPFNEYRKRFG+KPYTSFQEL GEKEMAAELEELYGDIDALEFY
Sbjct  447  LHVAVDVIKESREMRLQPFNEYRKRFGLKPYTSFQELTGEKEMAAELEELYGDIDALEFY  506

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKC PNSIFGESMIE+GAPFSLKGLLGNPICSPEYWKPSTFGG+VGFN+V TA+L
Sbjct  507  PGLLLEKCQPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKPSTFGGDVGFNLVNTASL  566

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSFRVPD   DDG  + R STEL
Sbjct  567  KKLVCLNTKTCPYVSFRVPDYPGDDGSVLVRRSTEL  602


>sp|Q63921.2|PGH1_RAT  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=602

 GENE ID: 24693 Ptgs1 | prostaglandin-endoperoxide synthase 1
[Rattus norvegicus] (Over 10 PubMed links)

 Score = 1023 bits (2645),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 508/576 (88%), Positives = 540/576 (93%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
             D G P+PVNPCCYYPCQ+QG+CVRFGLD YQCDCTRTGYSGPNCTIP +WTWLR+SLRP
Sbjct  27   TDAGVPSPVNPCCYYPCQNQGVCVRFGLDHYQCDCTRTGYSGPNCTIPEIWTWLRSSLRP  86

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSFTHFLLTHG W WEFVNATFIRE+LMRLV+TVRSNLIPSPPTYN+AHDYISWESFSN
Sbjct  87   SPSFTHFLLTHGYWIWEFVNATFIREVLMRLVITVRSNLIPSPPTYNTAHDYISWESFSN  146

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVPKDCPTPMGTKGKKQLPD  LLA+R LLRR+FIP PQGTN++FAFFAQH
Sbjct  147  VSYYTRILPSVPKDCPTPMGTKGKKQLPDIHLLAQRLLLRREFIPGPQGTNVLFAFFAQH  206

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGD+LERQY LRLFKDGKLKYQVLDGE+YPP
Sbjct  207  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDSLERQYHLRLFKDGKLKYQVLDGEVYPP  266

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVE+A VLM YP G+PP+ QMAVGQEVFGLLPGLML++T+WLREHNRVCDLLK EHPTW 
Sbjct  267  SVEQASVLMRYPPGVPPEKQMAVGQEVFGLLPGLMLFSTIWLREHNRVCDLLKEEHPTWD  326

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLILIGETIKI+IEEYVQ LSGYFLQLKFDPELLF  QFQYRNRIA+EFNHL
Sbjct  327  DEQLFQTTRLILIGETIKIIIEEYVQHLSGYFLQLKFDPELLFRAQFQYRNRIALEFNHL  386

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF+VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN D+H+
Sbjct  387  YHWHPLMPDSFQVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQRAGRIGGGRNFDYHV  446

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVA DVI+ESREMRLQ FNEYRKRFG+KPYTSFQE  GEKEMAAELEELYGDIDALEFY
Sbjct  447  LHVAEDVIKESREMRLQSFNEYRKRFGLKPYTSFQEFTGEKEMAAELEELYGDIDALEFY  506

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGL+LEKC PNS+FGESMIE+GAPFSLKGLLGNPICSPEYWKPSTFGG+VGFNIV TA+L
Sbjct  507  PGLMLEKCQPNSLFGESMIEMGAPFSLKGLLGNPICSPEYWKPSTFGGDVGFNIVNTASL  566

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSFRVPD   DDG    RPSTEL
Sbjct  567  KKLVCLNTKTCPYVSFRVPDYPGDDGSVFVRPSTEL  602


>sp|O62698.2|PGH2_BOVIN  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 282023 PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin
G/H synthase and cyclooxygenase) [Bos taurus] (Over 10 PubMed links)

 Score =  751 bits (1939),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 363/554 (65%), Positives = 451/554 (81%), Gaps = 1/554 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC +PCQ++G+C+  G D+Y+CDCTRTG+ G NCT P   T ++  L+P+P+  H++
Sbjct  18   ANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYI  77

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN  +F+R M+MR VLT RS+LI SPPTYN  + Y SWE+FSN+SYYTR 
Sbjct  78   LTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRA  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP VP DCPTPMG KG+K+LPD++ + ++ LLRRKFIPDPQGTNLMFAFFAQHFTHQFFK
Sbjct  138  LPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFK  197

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  + GP FTK   HGVDL HIYG++LERQ++LRLFKDGK+KYQ+++GEMYPP+V++  V
Sbjct  198  TDFERGPAFTKGKNHGVDLSHIYGESLERQHKLRLFKDGKMKYQMINGEMYPPTVKDTQV  257

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP WGDEQLFQT
Sbjct  258  EMIYPPHVPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQT  317

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  318  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLL  377

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD F++  QEY+Y+QF++N S+L+++G+   V++F+RQ AGR+ GGRN+   +  V+   
Sbjct  378  PDVFQIDGQEYNYQQFIYNNSVLLEHGLTQFVESFTRQRAGRVAGGRNLPVAVEKVSKAS  437

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I +SREM+ Q FNEYRKRF +KPY SF+EL GEKEMAAELE LYGDIDA+EFYP LL+EK
Sbjct  438  IDQSREMKYQSFNEYRKRFLVKPYESFEELTGEKEMAAELEALYGDIDAMEFYPALLVEK  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGE+M+E GAPFSLKGL+GNPICSPEYWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct  498  PRPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSN  557

Query  571  TKTCPYVSFRVPDA  584
             K CP+ SF V D 
Sbjct  558  VKGCPFTSFSVQDT  571


>sp|P27607.1|PGH2_CHICK  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
AltName: Full=Mitogen-inducible PGHS; Flags: Precursor
Length=603

 GENE ID: 396451 PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin
G/H synthase and cyclooxygenase) [Gallus gallus] (10 or fewer PubMed links)

 Score =  751 bits (1938),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 365/550 (66%), Positives = 451/550 (82%), Gaps = 1/550 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G+C+  G DRY+CDCTRTGY G NCT P  +TWL+  L+P+P+  H++L
Sbjct  19   NPCCSLPCQNRGVCMTTGFDRYECDCTRTGYYGENCTTPEFFTWLKLILKPTPNTVHYIL  78

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W  +N  +F+R+ +MR VLT RS+LI SPPTYNS + Y SWE++SN+SYYTR L
Sbjct  79   THFKGVWNIINNISFLRDTIMRYVLTSRSHLIDSPPTYNSDYSYKSWEAYSNLSYYTRSL  138

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P V  DCPTPMG KGKK+LPD++L+  +FLLRRKFIPDPQGTN+MF FFAQHFTHQFFKT
Sbjct  139  PPVGHDCPTPMGVKGKKELPDSKLIVEKFLLRRKFIPDPQGTNVMFTFFAQHFTHQFFKT  198

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GPGFTKA GHGVDL HIYG+ LERQ +LRL KDGKLKYQ++DGEMYPP+V++    
Sbjct  199  DHKKGPGFTKAYGHGVDLNHIYGETLERQLKLRLRKDGKLKYQMIDGEMYPPTVKDTQAE  258

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  +P   Q +VGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DEQLFQTT
Sbjct  259  MIYPPHVPEHLQFSVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDEQLFQTT  318

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRIA EFN LYHWHPL+P
Sbjct  319  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQRFQYQNRIAAEFNTLYHWHPLLP  378

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F++ +QEY+++QFL+N S+++++G+  +V +FS+Q AGR+ GG+N+   +  VA   I
Sbjct  379  DTFQIHNQEYTFQQFLYNNSIMLEHGLSHMVKSFSKQSAGRVAGGKNVPAAVQKVAKASI  438

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             +SR+MR Q  NEYRKRF +KP+ SF+EL GEKEMAAELEELYGDIDA+E YPGLL+EK 
Sbjct  439  DQSRQMRYQSLNEYRKRFMLKPFKSFEELTGEKEMAAELEELYGDIDAMELYPGLLVEKP  498

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             P +IFGE+M+EIGAPFSLKGL+GN ICSPEYWKPSTFGG+VGF I+ TA+L+KL+C N 
Sbjct  499  RPGAIFGETMVEIGAPFSLKGLMGNTICSPEYWKPSTFGGKVGFEIINTASLQKLICNNV  558

Query  572  KTCPYVSFRV  581
            K CP+ +F V
Sbjct  559  KGCPFTAFHV  568


>sp|O02768.1|PGH2_RABIT  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 100009248 COX-2 | cyclooxygenase-2 [Oryctolagus cuniculus]
(10 or fewer PubMed links)

 Score =  749 bits (1933),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 362/553 (65%), Positives = 448/553 (81%), Gaps = 1/553 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC  PCQ++G+C+  G D+Y+CDCTRTG+ G NC+ P   T ++  L+P+P   H++
Sbjct  18   ANPCCSNPCQNRGVCMTMGFDQYKCDCTRTGFYGENCSTPEFLTRIKLLLKPTPDTVHYI  77

Query  92   LTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN+  F+R  +M+ VLT RS++I SPPTYN  ++Y SWE+FSN+SYYTR 
Sbjct  78   LTHFKGVWNIVNSIPFLRNSIMKYVLTSRSHMIDSPPTYNVHYNYKSWEAFSNLSYYTRA  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP V  DCPTPMG KGKK+LPD++ +  + LLRRKFIPDPQGTN+MFAFFAQHFTHQFFK
Sbjct  138  LPPVADDCPTPMGVKGKKELPDSKDVVEKLLLRRKFIPDPQGTNMMFAFFAQHFTHQFFK  197

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  K GP FTK LGHGVDL HIYG+ L+RQ++LRLFKDGK+KYQV+DGE+YPP+V++  V
Sbjct  198  TDLKRGPAFTKGLGHGVDLNHIYGETLDRQHKLRLFKDGKMKYQVIDGEVYPPTVKDTQV  257

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  IP   Q AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DEQLFQT
Sbjct  258  EMIYPPHIPAHLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDEQLFQT  317

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  318  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLL  377

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F++  Q+Y+Y+QFL+N S+L+++G+   V++F+RQIAGR+ GGRN+   +  VA   
Sbjct  378  PDTFQIDDQQYNYQQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPPAVQKVAKAS  437

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I +SR+M+ Q  NEYRKRF +KPY SF+EL GEKEMAAELE LYGDIDA+E YP LL+E+
Sbjct  438  IDQSRQMKYQSLNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAVELYPALLVER  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGESM+E+GAPFSLKGL+GNPICSP YWKPSTFGGEVGF IV TA+++ L+C N
Sbjct  498  PRPDAIFGESMVEMGAPFSLKGLMGNPICSPNYWKPSTFGGEVGFKIVNTASIQSLICNN  557

Query  571  TKTCPYVSFRVPD  583
             K CP+ SF VPD
Sbjct  558  VKGCPFTSFNVPD  570


>sp|P79208.1|PGH2_SHEEP  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=603

 GENE ID: 443460 PGHS-2 | prostaglandin H synthase-2 [Ovis aries]
(10 or fewer PubMed links)

 Score =  748 bits (1932),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 362/554 (65%), Positives = 448/554 (80%), Gaps = 1/554 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC +PCQ++G+C+  G D+Y+CDCTRTG+ G NCT P   T ++  L+P+P   H++
Sbjct  17   ANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYI  76

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN  +F+R M+MR VLT RS+LI SPPTYN  + Y SWE+FSN+SYYTR 
Sbjct  77   LTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRA  136

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP VP DCPTPMG KG+K+LPD++ + ++ LLRRKFIPDPQGTNLMFAFFAQHFTHQFFK
Sbjct  137  LPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFK  196

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  + GP FTK   HGVDL H+YG++LERQ+  RLFKDGK+KYQ+++GEMYPP+V++  V
Sbjct  197  TDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQV  256

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  IP   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP WGDEQLFQT
Sbjct  257  EMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQT  316

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  317  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLL  376

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD F++  QEY+Y+QF++N S+L+++GV   V++F+RQIAGR+ G RN+   +  V+   
Sbjct  377  PDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKAS  436

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            + +SREM+ Q FNEYRKRF +KPY SF+EL GEKEMAAELE LYGDIDA+E YP LL+EK
Sbjct  437  LDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEK  496

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGE+M+E GAPFSLKGL+GNPICSPEYWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct  497  PAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSN  556

Query  571  TKTCPYVSFRVPDA  584
             K CP+ SF V DA
Sbjct  557  VKGCPFTSFSVQDA  570


>sp|P35354.2|PGH2_HUMAN  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 5743 PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H
synthase and cyclooxygenase) [Homo sapiens] (Over 100 PubMed links)

 Score =  744 bits (1920),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 357/553 (64%), Positives = 446/553 (80%), Gaps = 1/553 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC +PCQ++G+C+  G D+Y+CDCTRTG+ G NC+ P   T ++  L+P+P+  H++
Sbjct  18   ANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYI  77

Query  92   LTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH + FW  VN   F+R  +M  VLT RS+LI SPPTYN+ + Y SWE+FSN+SYYTR 
Sbjct  78   LTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRA  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP VP DCPTP+G KGKKQLPD+  +  + LLRRKFIPDPQG+N+MFAFFAQHFTHQFFK
Sbjct  138  LPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFK  197

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  K GP FT  LGHGVDL HIYG+ L RQ +LRLFKDGK+KYQ++DGEMYPP+V++   
Sbjct  198  TDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQA  257

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP WGDEQLFQT
Sbjct  258  EMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQT  317

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  318  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLL  377

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F++  Q+Y+Y+QF++N S+L+++G+   V++F+RQIAGR+ GGRN+   +  V+   
Sbjct  378  PDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQAS  437

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I +SR+M+ Q FNEYRKRF +KPY SF+EL GEKEM+AELE LYGDIDA+E YP LL+EK
Sbjct  438  IDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEK  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGE+M+E+GAPFSLKGL+GN ICSP YWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct  498  PRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNN  557

Query  571  TKTCPYVSFRVPD  583
             K CP+ SF VPD
Sbjct  558  VKGCPFTSFSVPD  570


>sp|Q05769.1|PGH2_MOUSE  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
AltName: Full=Glucocorticoid-regulated inflammatory cyclooxygenase; 
AltName: Full=Gripghs; AltName: Full=TIS10 protein; 
AltName: Full=Macrophage activation-associated marker protein 
P71/73; AltName: Full=PES-2; Flags: Precursor
Length=604

 GENE ID: 19225 Ptgs2 | prostaglandin-endoperoxide synthase 2 [Mus musculus]
(Over 100 PubMed links)

 Score =  740 bits (1910),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 362/561 (64%), Positives = 446/561 (79%), Gaps = 1/561 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            A  G     NPCC  PCQ++G C+  G D+Y+CDCTRTG+ G NCT P   T ++  L+P
Sbjct  10   AALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKP  69

Query  84   SPSFTHFLLTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFS  142
            +P+  H++LTH +  W  VN   F+R ++M+ VLT RS LI SPPTYN  + Y SWE+FS
Sbjct  70   TPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFS  129

Query  143  NVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaq  202
            N+SYYTR LP V  DCPTPMG KG K+LPD++ +  + LLRR+FIPDPQG+N+MFAFFAQ
Sbjct  130  NLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQ  189

Query  203  hfthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYP  262
            HFTHQFFKT  K GPGFT+ LGHGVDL HIYG+ L+RQ++LRLFKDGKLKYQV+ GE+YP
Sbjct  190  HFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYP  249

Query  263  PSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTW  322
            P+V++  V M YP  IP   Q AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W
Sbjct  250  PTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEW  309

Query  323  GDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNH  382
            GDEQLFQT+RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN 
Sbjct  310  GDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNT  369

Query  383  LYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHH  442
            LYHWHPL+PD+F +  QEYS++QFL+N S+L+++G+   V++F+RQIAGR+ GGRN+   
Sbjct  370  LYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIA  429

Query  443  ILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEF  502
            +  VA   I +SREM+ Q  NEYRKRF +KPYTSF+EL GEKEMAAEL+ LY DID +E 
Sbjct  430  VQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMEL  489

Query  503  YPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTAT  562
            YP LL+EK  P++IFGE+M+E+GAPFSLKGL+GNPICSP+YWKPSTFGGEVGF I+ TA+
Sbjct  490  YPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTAS  549

Query  563  LKKLVCLNTKTCPYVSFRVPD  583
            ++ L+C N K CP+ SF V D
Sbjct  550  IQSLICNNVKGCPFTSFNVQD  570


>sp|P70682.1|PGH2_CAVPO  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 100135607 Ptgs2 | prostaglandin-endoperoxide synthase 2
[Cavia porcellus] (10 or fewer PubMed links)

 Score =  738 bits (1906),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 360/552 (65%), Positives = 441/552 (79%), Gaps = 1/552 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G C+  G DRY+CDCTRTGY G NCT P   T ++  L+P+P+  H++L
Sbjct  19   NPCCSNPCQNRGECLSVGFDRYKCDCTRTGYYGENCTTPEFLTRIKLLLKPTPNTVHYIL  78

Query  93   THGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W  VN   F+R  +M  VLT RS+LI SPPTYN+ + Y SWE+FSN+SYYTR L
Sbjct  79   THFKGVWNIVNNIPFLRNAIMIYVLTSRSHLIDSPPTYNAHYGYKSWEAFSNLSYYTRAL  138

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P V  DCPTPMG KGKK+LPD+  +  + LLRRKFIPDPQGTN+MFAFFAQHFTHQFFK+
Sbjct  139  PPVADDCPTPMGVKGKKELPDSNEVLEKVLLRRKFIPDPQGTNMMFAFFAQHFTHQFFKS  198

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GP FT  L HGVDL HIYG+ L+RQ++LRLFKDGK+KYQ++DGEMYPP+V+E  V 
Sbjct  199  DQKRGPAFTTGLAHGVDLSHIYGETLDRQHKLRLFKDGKMKYQIIDGEMYPPTVKETQVE  258

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  IP  ++ AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DE+LFQT+
Sbjct  259  MMYPPYIPEHARFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDERLFQTS  318

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+P
Sbjct  319  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLP  378

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F++  Q Y+++QFL+N S+LV++G+   V++F++QIAGR+ GGRN+   +  VA   I
Sbjct  379  DTFQIDDQVYNFQQFLYNNSILVEHGLTQFVESFTKQIAGRVAGGRNVPLAVQRVAKASI  438

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
              SR+M+ Q  NEYRKRF MKPYTSF+EL GEKEMAA LE LYGDIDA+E YP LL+EK 
Sbjct  439  EHSRKMKYQSLNEYRKRFLMKPYTSFEELTGEKEMAAGLEALYGDIDAMELYPALLVEKP  498

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             P++IFGE+M+E+GAPFSLKGL+GNPICSP YWKPSTFGGEVGF IV TA+++ L+C N 
Sbjct  499  RPDAIFGETMVEMGAPFSLKGLMGNPICSPHYWKPSTFGGEVGFQIVNTASIQSLICNNV  558

Query  572  KTCPYVSFRVPD  583
            K CP  +F +PD
Sbjct  559  KGCPVTAFNLPD  570


>sp|O19183.1|PGH2_HORSE  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 791253 PGHS2 | prostaglandin G/H synthase-2 [Equus caballus]
(10 or fewer PubMed links)

 Score =  738 bits (1904),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 358/553 (64%), Positives = 446/553 (80%), Gaps = 1/553 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC  PCQ++G+C+  G D+YQCDCTRTG+ G NC+ P   T ++  L+P+P+  H++
Sbjct  18   ANPCCSNPCQNRGVCMSVGFDQYQCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYI  77

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN+  F+R  +M+ VL  RS+LI SPPTYN+ + Y SWESFSN+SYYTR 
Sbjct  78   LTHFKGVWNIVNSFPFLRNAVMKYVLVSRSHLIESPPTYNAQYGYKSWESFSNLSYYTRA  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP V   CPTPMG KGKK+LPD++ +  +FLLRRKFIPDPQGTN+MFAFFAQHFTHQFFK
Sbjct  138  LPPVADGCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGTNMMFAFFAQHFTHQFFK  197

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  K GP FTK LGHGVDL HIYG+ L+RQ++LRLFKDGK+KYQ+++GE+YPP+V++  V
Sbjct  198  TDPKRGPAFTKGLGHGVDLSHIYGETLDRQHKLRLFKDGKMKYQIINGEVYPPTVKDTQV  257

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  IP   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DE+LFQT
Sbjct  258  EMIYPPHIPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDERLFQT  317

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  318  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLL  377

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F++  QEY+++QFL+N S+L+++G+   V++FSRQIAGR+ GGRN+      +A   
Sbjct  378  PDTFQIDDQEYNFQQFLYNNSILLEHGLTQFVESFSRQIAGRVAGGRNVPAAAQKIAKAS  437

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I +SREM+ Q  NEYRKRF + PY SF+EL GEKEMAAELE LYGDIDA+E YP LL+EK
Sbjct  438  IDQSREMKYQSLNEYRKRFRLTPYKSFEELTGEKEMAAELEALYGDIDAMELYPALLVEK  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGE+M+E+GAPFSLKGLLGNPICSP+YWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct  498  PRPDAIFGETMVELGAPFSLKGLLGNPICSPDYWKPSTFGGEVGFKIINTASIQSLICNN  557

Query  571  TKTCPYVSFRVPD  583
             K CP+ +F V D
Sbjct  558  VKGCPFTAFSVQD  570


>sp|P35355.1|PGH2_RAT  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 29527 Ptgs2 | prostaglandin-endoperoxide synthase 2
[Rattus norvegicus] (Over 100 PubMed links)

 Score =  732 bits (1890),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 356/552 (64%), Positives = 444/552 (80%), Gaps = 1/552 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G C+  G D+Y+CDCTRTG+ G NCT P   T ++  L+P+P+  H++L
Sbjct  19   NPCCSNPCQNRGECMSIGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYIL  78

Query  93   THGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W  VN   F+R  +MR VLT RS+LI SPPTYN  + Y SWE+FSN+SYYTR L
Sbjct  79   THFKGVWNIVNNIPFLRNSIMRYVLTSRSHLIDSPPTYNVHYGYKSWEAFSNLSYYTRAL  138

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P V  DCPTPMG KG K+LPD++ +  + LLRR+FIPDPQGTN+MFAFFAQHFTHQFFKT
Sbjct  139  PPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGTNMMFAFFAQHFTHQFFKT  198

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GPGFT+ LGHGVDL H+YG+ L+RQ++LRLF+DGKLKYQV+ GE+YPP+V++  V 
Sbjct  199  DQKRGPGFTRGLGHGVDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQVD  258

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DE+LFQT+
Sbjct  259  MIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTS  318

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+P
Sbjct  319  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLP  378

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F +  QEY+++QFL+N S+L+++G+   V++F+RQIAGR+ GGRN+   +  VA   I
Sbjct  379  DTFNIEDQEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRVAGGRNVPIAVQAVAKASI  438

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             +SREM+ Q  NEYRKRF +KPYTSF+EL GEKEMAAEL+ LY DIDA+E YP LL+EK 
Sbjct  439  DQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYHDIDAMELYPALLVEKP  498

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             P++IFGE+M+E+GAPFSLKGL+GNPICSP+YWKPSTFGGEVGF I+ TA+++ L+C N 
Sbjct  499  RPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFRIINTASIQSLICNNV  558

Query  572  KTCPYVSFRVPD  583
            K CP+ SF V D
Sbjct  559  KGCPFASFNVQD  570


>sp|O62725.1|PGH2_MUSVI  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 Score =  707 bits (1824),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 343/556 (61%), Positives = 436/556 (78%), Gaps = 1/556 (0%)

Query  29   PTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFT  88
            P   NPCC  PCQ+QG+C+  G D+Y CDC+RTG+ G NC+ P   T ++  L+P+P+  
Sbjct  15   PHAANPCCSNPCQNQGVCMSIGFDQYMCDCSRTGFYGENCSTPEFLTRVKLLLKPTPNTV  74

Query  89   HFLLTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYY  147
            H++LTH +  W  VN   F+ +++M+ V T RS+ I  PPTYN  + Y SWE+FSN+SYY
Sbjct  75   HYILTHFKGVWNIVNKIPFLADVIMKYVRTSRSHCIEPPPTYNVHYAYKSWEAFSNLSYY  134

Query  148  TRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthq  207
            TR LP V  DCPTPMG KGKK+LPD++ +  +FLLRRKFIPDPQGTN+MFAFFAQHFTHQ
Sbjct  135  TRALPPVADDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGTNMMFAFFAQHFTHQ  194

Query  208  ffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEE  267
            FFKT  K GPGFTK LGHGVDL H+YG+ L+RQ++LRLFKDGK+KYQV+DGE+YPP+V++
Sbjct  195  FFKTDHKRGPGFTKGLGHGVDLSHVYGETLDRQHKLRLFKDGKMKYQVIDGEVYPPTVKD  254

Query  268  APVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQL  327
              V M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK E   W DE+L
Sbjct  255  TQVEMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEQGEWDDERL  314

Query  328  FQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWH  387
            F+ +RLILIGETIKIVIE+YV+ LSGY   LKFDPELLF  QFQY+NRIA EFN LYHWH
Sbjct  315  FRRSRLILIGETIKIVIEDYVRHLSGYHFSLKFDPELLFNQQFQYQNRIAAEFNTLYHWH  374

Query  388  PLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVA  447
            PL+PD+ ++  QEY+++QF++N S+L+++G+    ++FSRQIAGR+ GGRN+   +    
Sbjct  375  PLLPDTLQIDDQEYNFQQFVYNNSILLEHGLTQFGESFSRQIAGRVAGGRNVPAAVQQEQ  434

Query  448  VDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLL  507
               I +SR+M+ Q  NEYRKRF +KPY SF+EL GEKEMA EL+ LY DIDA+E YP LL
Sbjct  435  RASIDQSRQMKYQSLNEYRKRFSVKPYASFEELTGEKEMAGELKALYQDIDAMELYPALL  494

Query  508  LEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLV  567
            +EK  P++IFGE+M+EIGAPFSLKGL+GNPICSP+YWKPS FGGEVGF I+ TA+++ L+
Sbjct  495  VEKPRPDAIFGETMVEIGAPFSLKGLMGNPICSPDYWKPSHFGGEVGFKIINTASIQSLI  554

Query  568  CLNTKTCPYVSFRVPD  583
            C N K CP+ +F V D
Sbjct  555  CNNVKGCPFTAFSVQD  570


>sp|Q7QH73.3|PERC_ANOGA  RecName: Full=Chorion peroxidase; Contains: RecName: Full=Chorion 
peroxidase light chain; Contains: RecName: Full=Chorion 
peroxidase heavy chain; Flags: Precursor
Length=767

 Score = 83.2 bits (204),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 103/409 (25%), Positives = 167/409 (40%), Gaps = 53/409 (12%)

Query  213  GKMGPGFTKALG---HGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAP  269
            GK   G+ K L    H +D   +YG N      LR F+ G+L+     GE   P      
Sbjct  350  GKCRLGYGKQLNRVTHFIDGSAVYGSNEALAASLRTFEGGRLRSSFPTGEELLPFARTRA  409

Query  270  VLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQ  329
                + +          G +    +  L    TL+LREHNRV   L A +  W DE+L+Q
Sbjct  410  ACEPWAKAC-----FRAGDDRVNQIVSLTEMHTLFLREHNRVATALAALNRHWDDERLYQ  464

Query  330  TTRLILIGETIKIVIEEYVQQLSGYFLQLK-------------FDPEL-------LFGVQ  369
             TR I+     KI   EY+  + G+    +             + P++       L G  
Sbjct  465  ETRRIVGAVMQKIFYNEYLPSIVGHSKARQYGLLDSHGEQTDFYSPDVKPAVFNELSGAA  524

Query  370  FQYRNRI---AMEFNHLYHWHPLMP--DSFKVGS---QEYSYEQFLFNTSMLVDYGVEAL  421
            F++ +     A    H +    L+P  + F   S   Q   ++ FLF+   L+D   + L
Sbjct  525  FRFGHSTVDGAFLIQHRHRRTELVPIQEVFLNPSRLLQRSFFDDFLFS---LMDQPQQQL  581

Query  422  VDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELV  481
             D+ +  +   +  GRN     L  A   I+  R+  L+P+N+YR   G++  TSF++  
Sbjct  582  DDSITFGLTRLLFAGRNPFGSDL--ASLNIQRGRDHALRPYNDYRSWAGLERLTSFEQF-  638

Query  482  GEKEMAAELEELYGDIDALEFYPGLLLE-KCHPNSIFGESMIEIGAPFSLKGLLGNP--I  538
                + A L  +Y   D ++ + G LLE      ++FGE+   I +    +   G+    
Sbjct  639  --GPVGARLASVYEFPDDVDLWVGGLLEPPTQDGALFGETFAAIISEQFARLKFGDRYYY  696

Query  539  CSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTK-----TCPYVSFRVP  582
             +     P  F GE    + K  +L  ++C N       + P  +FR P
Sbjct  697  TNGPRTNPGFFTGEQLRELSKV-SLASVICANLDQADGFSAPRDAFRQP  744


>sp|P82600.3|PERC_AEDAE  RecName: Full=Chorion peroxidase; Contains: RecName: Full=Chorion 
peroxidase light chain; Contains: RecName: Full=Chorion 
peroxidase heavy chain; Flags: Precursor
Length=790

 Score = 78.6 bits (192),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 79/324 (24%), Positives = 141/324 (43%), Gaps = 33/324 (10%)

Query  225  HGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQM  284
            H +D   +YG   +   +LR F+ G+LK      + +P  +E  P   +    +P     
Sbjct  387  HFLDASTVYGSTNDVAAELRAFQQGRLK------DSFPNGIELLPFARNRTACVPWARVC  440

Query  285  AVGQEV-FGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIV  343
              G ++    L GL +  TL++REHNR+   L   +P W DE+L+Q  R ILI E   +V
Sbjct  441  YEGGDIRTNQLLGLTMVHTLFMREHNRLAVGLSKINPHWDDERLYQEARRILIAEYQNVV  500

Query  344  IEEYVQQLSGYFLQLKFDPELLFGVQFQY-----RNRIAMEFNHLYHW--HPLMPDSFKV  396
              E++  L G+    +      F     Y     R     E     H   H L+   F+ 
Sbjct  501  YNEFLPILLGHERVQQLGLADPFDTYTNYYDPNLRPMTLAEVGAAAHRYGHSLVEGFFRF  560

Query  397  GSQEYSYEQF----LFN--TSMLVDYGVEALVDAFSRQIAGRI------GGGRNMDHHIL  444
             ++E   E      +FN  +  L     + ++ +F++Q   ++      G  R +     
Sbjct  561  LTRESPPEDVFIKDIFNDPSKTLEPNSFDVMMFSFNQQPMEQMDRFLTYGLTRFLFKERK  620

Query  445  HVAVDV----IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDAL  500
                D+    I+  R+  ++P+N+YR+  G+   T F +L    E+ A L ++Y   D +
Sbjct  621  PFGSDLASLNIQRGRDFAVRPYNDYREWAGLGRITDFNQL---GEVGALLAQVYESPDDV  677

Query  501  EFYPGLLLEKCHPNSIFGESMIEI  524
            + +PG +LE     ++ G + + +
Sbjct  678  DLWPGGVLEPPAEGAVVGSTFVAL  701


>sp|O61213.2|DUOX1_CAEEL  RecName: Full=Dual oxidase 1; Short=DUOX1; AltName: Full=NADPH 
thyroid oxidase 1; AltName: Full=Blistered cuticle protein 
3; Flags: Precursor
Length=1497

 GENE ID: 171608 bli-3 | BLIstered cuticle [Caenorhabditis elegans]
(10 or fewer PubMed links)

 Score = 73.6 bits (179),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 93/334 (27%), Positives = 146/334 (43%), Gaps = 50/334 (14%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLK-----YQVLDGEMYPPSVEEAPVLMHYPRGIPPQ  281
            +D   IYG        LR FK G+L      Y  L+    P +   AP  +H  R + P 
Sbjct  170  IDGSFIYGTTQPWVSSLRSFKQGRLAEGVPGYPPLNNPHIPLN-NPAPPQVH--RLMSPD  226

Query  282  SQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIK  341
                +G       PGL+ +  +  R HN   + +  EHP W DEQ+FQ  R ++I    K
Sbjct  227  RLFMLGDSRVNENPGLLSFGLILFRWHNYNANQIHREHPDWTDEQIFQAARRLVIASMQK  286

Query  342  IVIEEYVQQLSGYFLQL----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSF---  394
            I+  ++V  L G  ++L    K+ P +  G+   +    A  F      H ++P +    
Sbjct  287  IIAYDFVPGLLGEDVRLSNYTKYMPHVPPGISHAF-GAAAFRFP-----HSIVPPAMLLR  340

Query  395  KVGSQ-EYSYE----------QFLFNTSMLV-DYGVEALVDAFSRQIAGR-----IGGGR  437
            K G++ E+  E          Q  +N   +V +Y V+ ++   + QIA R     +   R
Sbjct  341  KRGNKCEFRTEVGGYPALRLCQNWWNAQDIVKEYSVDEIILGMASQIAERDDNIVVEDLR  400

Query  438  N-----MDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYT--SFQELVGEKEMAA--  488
            +     M    L V    I   R+  + P+NE R+ FG+ P T  +  E   +K  A   
Sbjct  401  DYIFGPMHFSRLDVVASSIMRGRDNGVPPYNELRRTFGLAPKTWETMNEDFYKKHTAKVE  460

Query  489  ELEELY-GDIDALEFYPGLLLE--KCHPNSIFGE  519
            +L+ELY G+I  L+ Y G +LE  +  P  +F E
Sbjct  461  KLKELYGGNILYLDAYVGGMLEGGENGPGELFKE  494


>sp|Q9UUS2.1|LIDS_GAEGR  RecName: Full=Linoleate diol synthase; AltName: Full=Linoleate 
(8R)-dioxygenase; Short=Linoleate 8-dioxygenase
Length=978

 Score = 68.2 bits (165),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 79/349 (22%), Positives = 131/349 (37%), Gaps = 91/349 (26%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAV  286
            +DL  +YG N + Q  +R  KDG LK                                  
Sbjct  222  LDLSPLYGRNHDEQMAVRTGKDGLLKPDTFSS----------------------------  253

Query  287  GQEVFGLLPGLMLYATLWLREHNRVCDLL-------KAEHPT-------WG--DEQLFQT  330
             + V G  PG+  +  ++ R HN V   L       + + PT       W   D  LFQT
Sbjct  254  -KRVIGFPPGVGAFLIMFNRFHNYVVTQLAKINEGGRFKRPTTPDDTAGWETYDNSLFQT  312

Query  331  TRLILIGETIKIVIEEYVQ---QLSGYFLQLKFDPELLFGVQFQYR-------NRIAMEF  380
             RLI  G  I IV+ +YV+    L+        DP    G     +       N++++EF
Sbjct  313  GRLITCGLYINIVLGDYVRTILNLNRANTTWNLDPRTKEGKSLLSKPTPEAVGNQVSVEF  372

Query  381  NHLYHWHPLMPDSFK----------VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIA  430
            N +Y WH  + +             +G Q+ +  +       L  +      +   R +A
Sbjct  373  NLIYRWHCTISERDDKWTTNAMREALGGQDPATAKMEDVMRALGMFEKNIPDEPEKRTLA  432

Query  431  G--RIGGGRNMDHHILHV----------------------AVDV--IRESREMRLQPFNE  464
            G  R   G   D  ++ +                      A+++  I++SR   +   NE
Sbjct  433  GLTRQSDGAFDDTELVKILQESIEDVAGAFGPNHVPACMRAIEILGIKQSRTWNVATLNE  492

Query  465  YRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHP  513
            +R+  G+ P+ SF  +  + ++   L ++Y   DA+E YPG++ E   P
Sbjct  493  FRQFIGLTPHDSFYHMNPDPKICKILAQMYDSPDAVELYPGIMAEAAKP  541


>sp|Q92626.2|PXDN_HUMAN  RecName: Full=Peroxidasin homolog; AltName: Full=Vascular peroxidase 
1; AltName: Full=Melanoma-associated antigen MG50; AltName: 
Full=p53-responsive gene 2 protein; Flags: Precursor
Length=1479

 GENE ID: 7837 PXDN | peroxidasin homolog (Drosophila) [Homo sapiens]
(10 or fewer PubMed links)

 Score = 66.2 bits (160),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 77/336 (22%), Positives = 141/336 (41%), Gaps = 41/336 (12%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
             GL    TLW REHNR+   L   +P W  + ++  TR I+  E   I  + ++ ++ G  
Sbjct  983   GLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEV  1042

Query  356   LQLK------FDPELLFGVQFQYRNRIAMEFNHLYHWHPL---MPDSFKVGSQEY-SYEQ  405
                       +DP +  G+ F      A  F H    +PL   + ++F+  +Q++    +
Sbjct  1043  GMRTLGEYHGYDPGINAGI-FNAFATAAFRFGHTL-VNPLLYRLDENFQPIAQDHLPLHK  1100

Query  406   FLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHVAVD  449
               F+   +V+   E  +D   R + G  G  R               +M H + L +A  
Sbjct  1101  AFFSPFRIVN---EGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAI  1157

Query  450   VIRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGL  506
              I+  R+  + P+++YR    +    +F++L  E    E+  +L+ LYG    ++ +P L
Sbjct  1158  NIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPAL  1217

Query  507   LLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKL  566
             ++E   P S  G +++ + +    +   G+ +    Y  P  F        +K  +L ++
Sbjct  1218  VVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLW---YENPGVF-SPAQLTQIKQTSLARI  1273

Query  567   VCLNTKTCPYVS---FRVPDASQDDGPAVERPSTEL  599
             +C N      V    FRV +     G   E P  +L
Sbjct  1274  LCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDL  1309


>sp|Q8HZK3.1|DUOX1_PIG  RecName: Full=Dual oxidase 1; Flags: Precursor
Length=1553

 GENE ID: 397177 DUOX1 | dual oxidase 1 [Sus scrofa] (10 or fewer PubMed links)

 Score = 63.9 bits (154),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 75/296 (25%), Positives = 116/296 (39%), Gaps = 57/296 (19%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYP-------RGIP  279
            +D   IYG +     +LR F  G+L       +   P   + P+ M  P       RG  
Sbjct  173  LDGSAIYGSSHSWSDELRSFSGGQLAS---GPDPAFPRQAQDPLFMWTPPDPATGQRG--  227

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
            PQ   A G E     P L     LW R HN     L  EHP WGDE+LFQ  R  +I   
Sbjct  228  PQGLYAFGAEQGNREPFLQALGLLWFRYHNLCAQKLAREHPLWGDEELFQHARKRVIATY  287

Query  340  IKIVIEEYV--------QQLSGY--FLQLKFDPELLFGV-QF--------QYRNRIAMEF  380
              I + E++        Q+ +GY  FL     PE L    QF         Y    +  F
Sbjct  288  QSITMYEWLPSFLRKMPQEYTGYRPFLDPSISPEFLAASEQFFSTMVPPGVYMRNASCHF  347

Query  381  NHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMD  440
              + + +  +  + +V +  +S E    + ++     V+AL+   + QIA R       D
Sbjct  348  QGVINRNSSVSRALRVCNSYWSRE----HPNLQRAEDVDALLLGMASQIAER------ED  397

Query  441  HHILHVAVD----------------VIRESREMRLQPFNEYRKRFGMKPYTSFQEL  480
            H ++    D                 ++  R++ L  + + R R G+ P T +Q++
Sbjct  398  HMVVEDVQDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARARLGLPPVTRWQDI  453


>sp|Q9VEG6.2|PERC_DROME  RecName: Full=Chorion peroxidase; AltName: Full=Peroxinectin-related 
protein; Short=Dpxt; Contains: RecName: Full=Chorion 
peroxidase light chain; Contains: RecName: Full=Chorion peroxidase 
heavy chain; Flags: Precursor
Length=831

 Score = 63.2 bits (152),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 96/415 (23%), Positives = 158/415 (38%), Gaps = 77/415 (18%)

Query  216  GPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQ---------VLDGEMYPPSVE  266
            G   TK + H VD   +YG + E    LR F+ G+L+           + + +   PS E
Sbjct  394  GKQLTK-VTHFVDASPVYGSSDEASRSLRAFRGGRLRMMNDFGRDLLPLTNDKKACPSEE  452

Query  267  EAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT------------------LWLREH  308
                  H        S  ++   VF ++  L+ Y T                  L  REH
Sbjct  453  AGKSCFH--------SGKSLLSNVFLIINSLITYLTRLGDGRTNQIISLITLQILLAREH  504

Query  309  NRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG--YFLQLKFDPELLF  366
            NRV   L   +P+  DE LFQ  R I+I E   I   E++  + G     + +  P L  
Sbjct  505  NRVAGALHELNPSASDETLFQEARRIVIAEMQHITYNEFLPIIIGPQQMKRFRLVP-LHQ  563

Query  367  GVQFQYRNR----IAMEFNHLYHW--HPLMPDSFKVGSQEYSYEQ------FLFNTSML-  413
            G    Y       I  EF+   +   H  +   F++  +    ++       +FN S + 
Sbjct  564  GYSHDYNVNVNPAITNEFSGAAYRMGHSSVDGKFQIRQEHGRIDEVVNIPDVMFNPSRMR  623

Query  414  ----VDYGVEALVDAFSRQIAGRIGGG------RNMDHHILHVAVDVIRESREMRLQPFN  463
                 D  +  L     +Q+   I  G      R  +   L +A   I+  R+  L+ +N
Sbjct  624  KREFYDDMLRTLYSQPMQQVDSSISQGLSRFLFRGDNPFGLDLAAINIQRGRDQGLRSYN  683

Query  464  EYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIE  523
            +Y +  G     SF++     E+A +L  +Y   D ++ + G LLEK     + G +  E
Sbjct  684  DYLELMGAPKLHSFEQF--PIEIAQKLSRVYRTPDDIDLWVGGLLEKAVEGGVVGVTFAE  741

Query  524  IGAPFSLKGLLGNPICSPEYW-------KPSTFGGEVGFNIVKTATLKKLVCLNT  571
            I A    +   G+      Y+        P  F   +    ++  TL +L+C N+
Sbjct  742  IIADQFARFKQGD-----RYYYEYDNGINPGAF-NPLQLQEIRKVTLARLLCDNS  790


>sp|Q3UQ28.1|PXDN_MOUSE  RecName: Full=Peroxidasin homolog; Flags: Precursor
Length=1475

 GENE ID: 69675 Pxdn | peroxidasin homolog (Drosophila) [Mus musculus]
(Over 10 PubMed links)

 Score = 60.8 bits (146),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 76/336 (22%), Positives = 143/336 (42%), Gaps = 48/336 (14%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
             GL    TLW REHNR+   L   +P W  + ++  TR I+  E   I    ++ ++ G  
Sbjct  980   GLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHETRKIVGAEIQHITYRHWLPKILGE-  1038

Query  356   LQLK-------FDPELLFGVQFQYRNRIAMEFNHLYHWHPLM---PDSFK-VGSQEYSYE  404
             + +K       +DP +  G+ F      A  F H    +PL+    ++F+ +        
Sbjct  1039  VGMKMLGEYRGYDPSVNAGI-FNAFATAAFRFGHTL-INPLLYRLDENFEPIPQGHVPLH  1096

Query  405   QFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHVAV  448
             +  F+   +V+   E  +D   R + G  G  R               +M H + L +A 
Sbjct  1097  KAFFSPFRIVN---EGGIDPLLRGLFGVAGKMRIPSQLLNTELTERLFSMAHTVALDLAA  1153

Query  449   DVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKE---MAAELEELYGDIDALEFYPG  505
               I+  R+  + P+++YR    +    +F++L  E +   +  +L+ LYG    ++ +P 
Sbjct  1154  INIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIKSPVIREKLQRLYGSTLNIDLFPA  1213

Query  506   LLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKK  565
             L++E   P S  G +++ + +    +   G+ +    Y  P  F        +K  +L +
Sbjct  1214  LMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLW---YENPGVF-SPAQLTQLKQTSLAR  1269

Query  566   LVCLNTKTCPYVS---FRVPD-----ASQDDGPAVE  593
             ++C N+     V    FRV +     +S +D P V+
Sbjct  1270  ILCDNSDNITRVQQDVFRVAEFPHGYSSCEDIPRVD  1305


>sp|A1KZ92.2|PXDNL_HUMAN  RecName: Full=Peroxidasin-like protein; AltName: Full=Vascular 
peroxidase 2; AltName: Full=Cardiac peroxidase; Flags: Precursor
Length=1463

 GENE ID: 137902 PXDNL | peroxidasin homolog (Drosophila)-like [Homo sapiens]
(10 or fewer PubMed links)

 Score = 56.6 bits (135),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 74/340 (21%), Positives = 137/340 (40%), Gaps = 61/340 (17%)

Query  227   VDLGHIYGDNLERQYQLRLFKDGKLKYQVLD-GEMYPPSVEEAPVLMHYPRGIPPQSQMA  285
             +D  ++YG + ER+ Q    +D  +   +L  G  +PPS +    L+ +  G PP     
Sbjct  894   IDGSNVYGSS-ERESQA--LRDPSVPRGLLKTGFPWPPSGKP---LLPFSTG-PPTECAR  946

Query  286   VGQEVFGLLPG---------LMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI  336
               QE    L G         L    TLW REHNRV   L A +P W    ++Q  R I+ 
Sbjct  947   QEQESPCFLAGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVG  1006

Query  337   GETIKIVIEEYV---------QQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNH-----  382
              E   I    ++         + L GY     ++P +  G+   +    A  F H     
Sbjct  1007  AELQHITYSHWLPKVLGDPGTRMLRGY---RGYNPNVNAGIINSFAT-AAFRFGHTLINP  1062

Query  383   -LYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDH  441
              LY  +  + +   +      + + LF+ S ++    E  +D   R + G     R   +
Sbjct  1063  ILYRLNATLGE---ISEGHLPFHKALFSPSRIIK---EGGIDPVLRGLFGVAAKWRAPSY  1116

Query  442   HI----------------LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VG  482
              +                +  A  +I+  R+  + P+ ++R    +    +F++L   + 
Sbjct  1117  LLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIK  1176

Query  483   EKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI  522
             + E+  +L +LYG    ++ +P L++E   P +  G +++
Sbjct  1177  DSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLM  1216


>sp|Q9VZZ4.1|PXDN_DROME  RecName: Full=Peroxidasin; Flags: Precursor
Length=1527

 Score = 56.2 bits (134),  Expect = 5e-07, Method: Compositional matrix adjust.
 Identities = 56/240 (23%), Positives = 113/240 (47%), Gaps = 28/240 (11%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQL---S  352
             GL+   T+W+REHNR+   LK  +  W  + L+Q  R I+  +   I  ++++  +   S
Sbjct  1018  GLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGES  1077

Query  353   GYFLQLKF---DPELLFGVQFQYRNRIAMEFNHLYHWHPLM---PDSFKVGSQEYS--YE  404
             G  +  ++   +P+L   +  ++    A+ F H    +P++    ++F+   Q +   ++
Sbjct  1078  GMEMMGEYQGYNPQLNPSIANEFAT-AALRFGHTI-INPILHRLNETFQPIPQGHLLLHK  1135

Query  405   QFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILH--------VAVDV----IR  452
              F     +  + GV+ L+  F    A      +N++  +          VA+D+    I+
Sbjct  1136  AFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQ  1195

Query  453   ESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGLLLE  509
               R+  +  +N YRK   +     F++L GE    E+  +++ELYG  D ++ + G +LE
Sbjct  1196  RGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILE  1255


>sp|Q9MZF4.1|DUOX1_CANFA  RecName: Full=Dual oxidase 1; AltName: Full=NADPH thyroid oxidase 
1; Short=Thyroid oxidase 1; Flags: Precursor
Length=1551

 GENE ID: 403720 DUOX1 | dual oxidase 1 [Canis lupus familiaris]
(10 or fewer PubMed links)

 Score = 55.8 bits (133),  Expect = 6e-07, Method: Compositional matrix adjust.
 Identities = 74/301 (24%), Positives = 115/301 (38%), Gaps = 51/301 (16%)

Query  219  FTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQ---VLDGEMYPPSVE-EAPVLMHY  274
             T A+   +D   IYG +      LR F  G+L             PP +   AP     
Sbjct  165  LTNAVTGWLDGSAIYGSSHSWSDALRSFSGGQLASGPDPAFPRNAQPPLLMWSAPDPASG  224

Query  275  PRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLI  334
             RG  P    A G E     P L     LW R HN     L  +HP WGDE+LFQ  R  
Sbjct  225  QRG--PGGLYAFGAERGNRDPFLQALGLLWFRYHNLCAQRLARQHPHWGDEELFQHARKR  282

Query  335  LIGETIKIVIEE----YVQQL----SGY--FLQLKFDPELLFGV-QF--------QYRNR  375
            +I     I + E    ++QQ     +GY  FL     PE L    QF         Y   
Sbjct  283  VIATYQNIALYEWLPSFLQQAPVKYAGYNPFLDPSISPEFLVASEQFFSTMVPPGIYMRN  342

Query  376  IAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGG  435
             +  F  + + +  +  + +V +  +S +    + ++     V+AL+   + QIA R   
Sbjct  343  ASCHFQEVINRNSSISRALRVCNSYWSRK----HPNLRRAEDVDALLLGMASQIAER---  395

Query  436  GRNMDHHILHVAVD----------------VIRESREMRLQPFNEYRKRFGMKPYTSFQE  479
                DH ++   +D                 ++  R++ L  + + R   G+ P T +Q+
Sbjct  396  ---EDHVVVEDVLDFWPGSLKFSRTDHVAGCLQRGRDLGLPSYTKARAALGLPPITRWQD  452

Query  480  L  480
            +
Sbjct  453  I  453


>sp|Q01603.1|PERO_DROME  RecName: Full=Peroxidase; Short=DmPO; AltName: Full=Chorion peroxidase; 
Flags: Precursor
Length=690

 Score = 55.5 bits (132),  Expect = 8e-07, Method: Compositional matrix adjust.
 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 18/130 (13%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAV  286
            +DL  +YG+++++   +R F+ G++  +  +G  + P            R +        
Sbjct  270  LDLSLVYGNSIQQNSDIREFQGGRMIVEERNGAKWLP----------LSRNVTGDCDAVD  319

Query  287  GQEV--------FGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGE  338
              EV            PGL +  T+ LREHNR+ D L A +P + D  LFQ  R I I +
Sbjct  320  ASEVCYRSGDVRVNQNPGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQ  379

Query  339  TIKIVIEEYV  348
              +I   E++
Sbjct  380  YQQISYYEWL  389


>sp|P35419.1|PERT_MOUSE  RecName: Full=Thyroid peroxidase; Short=TPO; Flags: Precursor
Length=914

 GENE ID: 22018 Tpo | thyroid peroxidase [Mus musculus] (Over 10 PubMed links)

 Score = 54.7 bits (130),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 73/337 (21%), Positives = 136/337 (40%), Gaps = 38/337 (11%)

Query  294  LPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG  353
            +P L    TLWLREHNR+    KA +  W     +Q  R ++      I + +Y+ ++ G
Sbjct  388  VPALAAVHTLWLREHNRLASAFKAINKHWSANTAYQEARKVVGALHQIITMRDYIPKILG  447

Query  354  --YFLQL-----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYS----  402
               F Q       ++P +   V   + +  A  F H    HPL+        QE++    
Sbjct  448  PDAFRQYVGPYEGYNPTVNPTVSNIF-STAAFRFGHATV-HPLV-RRLNTDFQEHTELPR  504

Query  403  ---YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI------------LHVA  447
                + F     ++ + G++ +V     + A     G+ M+  +            L +A
Sbjct  505  LQLRDVFFRPWRLIQEGGLDPIVRGLLARAAKLQVQGQLMNEELTERLFVLSNVGTLDLA  564

Query  448  VDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYP  504
               ++  R+  L  +NE+R+  G+    +  EL   +  + M  ++ +LY   D ++ + 
Sbjct  565  SLNLQRGRDHGLPDYNEWREFCGLSRLETPAELNKAIANRSMVNKIMDLYKHADNIDVWL  624

Query  505  GLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLK  564
            G L EK  P +  G     I     +K L         +W+ +    +     ++  +L 
Sbjct  625  GGLAEKFLPGARTGPLFACIIGK-QMKALRDG---DRFWWENTNVFTDAQRQELEKHSLP  680

Query  565  KLVCLNT--KTCPYVSFRVPDASQDDGPAVERPSTEL  599
            +++C NT     P  +FR+    QD     + PS +L
Sbjct  681  RVICDNTGLTRVPVDAFRIGKFPQDFESCEDIPSMDL  717


>sp|P11247.1|PERM_MOUSE  RecName: Full=Myeloperoxidase; Short=MPO; Contains: RecName: 
Full=Myeloperoxidase light chain; Contains: RecName: Full=Myeloperoxidase 
heavy chain; Flags: Precursor
Length=718

 GENE ID: 17523 Mpo | myeloperoxidase [Mus musculus] (Over 100 PubMed links)

 Score = 54.3 bits (129),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 73/315 (23%), Positives = 141/315 (44%), Gaps = 53/315 (16%)

Query  294  LPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVI-EEYVQQLS  352
            +P L    TL++REHNR+   LK  +P W  E+L+Q  R I +G  ++I+   +Y+  + 
Sbjct  383  MPELTSMHTLFVREHNRLATQLKRLNPRWNGEKLYQEARKI-VGAMVQIITYRDYLPLVL  441

Query  353  GYFLQLKFDPELLFGVQFQYRN-------RIAMEFNHLYHW-HPLM-PDSFKVGSQEYSY  403
            G     K+ P        QYR+       RIA  F + + + H L+ P  F++ +Q    
Sbjct  442  GPAAMKKYLP--------QYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLNNQYRPT  493

Query  404  ---------EQFLFNTSMLVDYGVEALVDA-------FSRQIAGRIGGGR-NMDHHILHV  446
                     + F  +  ++++ G++ ++          +RQ    +   R  +   ++ +
Sbjct  494  AANPRVPLSKVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIVVDEIRERLFEQVMRI  553

Query  447  AVDV----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDA  499
             +D+    ++ SR+  L  +N +R+  G+   ++  EL   +   E+A +L   YG  + 
Sbjct  554  GLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNN  613

Query  500  LEFYPGLLLEKCHPNSIFGESM-IEIGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFN  556
            ++ + G + E   PN   G+ +   IG  F  K   G+      +W   P  F  +    
Sbjct  614  IDIWMGGVSEPLEPNGRVGQLLACLIGTQFR-KLRDGD-----RFWWENPGVFSKQ-QRQ  666

Query  557  IVKTATLKKLVCLNT  571
             + + +L +L+C NT
Sbjct  667  ALASISLPRLICDNT  681


>sp|P14650.1|PERT_RAT  RecName: Full=Thyroid peroxidase; Short=TPO; Flags: Precursor
Length=914

 GENE ID: 54314 Tpo | thyroid peroxidase [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 53.9 bits (128),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 90/413 (21%), Positives = 159/413 (38%), Gaps = 51/413 (12%)

Query  227  VDLGHIYGDNLERQYQLRLFKD--GKLKYQVL---DGEMYPPSVEEAPVLMHYPRGIPPQ  281
            +D   +YG +   + QLR +    G L+   L    G  Y P    A      P    P 
Sbjct  316  LDASTVYGSSPGVEKQLRNWSSSAGLLRVNTLHLDSGRAYLPFASAACA----PEPGAPH  371

Query  282  SQMA----VGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG  337
            +        G      +P L    TLWLREHNR+    KA +  W     +Q  R ++  
Sbjct  372  ANRTPCFLAGDGRASEVPALAAVHTLWLREHNRLATAFKAINTHWSANTAYQEARKVVGA  431

Query  338  ETIKIVIEEYVQQLSG--YFLQL-----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
                I + +Y+ ++ G   F Q       ++P +   V   + +  A  F H    HPL+
Sbjct  432  LHQIITMRDYIPKILGPDAFRQYVGPYEGYNPTVNPTVSNVF-STAAFRFGHATV-HPLV  489

Query  391  PDSFKVGSQEYS-------YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
                    Q+++       ++ F     ++ + G++ +V     + A      + M+  +
Sbjct  490  -RRLNTDFQDHTELPRLQLHDVFFRPWRLIQEGGLDPIVRGLLARPAKLQVQEQLMNEEL  548

Query  444  ------------LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAA  488
                        L +A   ++  R+  L  +NE+R+  G+    +  EL   +  + M  
Sbjct  549  TERLFVLSNVGTLDLASLNLQRGRDHGLPGYNEWREFCGLSRLDTGAELNKAIANRSMVN  608

Query  489  ELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPST  548
            ++ ELY   D ++ + G L EK  P +  G     I     +K L         +W+ S 
Sbjct  609  KIMELYKHADNIDVWLGGLAEKFLPGARTGPLFACIIGK-QMKALRDG---DRFWWENSH  664

Query  549  FGGEVGFNIVKTATLKKLVCLNT--KTCPYVSFRVPDASQDDGPAVERPSTEL  599
               +     ++  +L +++C NT     P  +FR+    QD     E PS +L
Sbjct  665  VFTDAQRQELEKHSLPRVICDNTGLTRVPVDAFRIGKFPQDFESCEEIPSMDL  717


>sp|Q8HZK2.2|DUOX2_PIG  RecName: Full=Dual oxidase 2; AltName: Full=NADH/NADPH thyroid 
oxidase p138-tox; Flags: Precursor
Length=1545

 GENE ID: 397060 DUOX2 | dual oxidase 2 [Sus scrofa] (10 or fewer PubMed links)

 Score = 53.5 bits (127),  Expect = 4e-06, Method: Compositional matrix adjust.
 Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 12/129 (9%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYP-------RGIP  279
            +D   IYG +     +LR F  G+L       +   P   + P+ M  P       RG  
Sbjct  179  LDGSAIYGSSHSWSDELRSFSGGQLAS---GPDPAFPRQAQDPLFMWTPPDPATGQRG--  233

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
            PQ   A G E     P L     LW R HN     L  EHP WGDE+LFQ  R  +I   
Sbjct  234  PQGLYAFGAEQGNREPFLQALGLLWFRYHNLCAQKLAREHPLWGDEELFQHARKRVIATY  293

Query  340  IKIVIEEYV  348
              I + E++
Sbjct  294  QSITMYEWL  302


>sp|Q8CIY2.1|DUOX1_RAT  RecName: Full=Dual oxidase 1; Flags: Precursor
Length=1551

 GENE ID: 266807 Duox1 | dual oxidase 1 [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 53.1 bits (126),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 67/293 (22%), Positives = 111/293 (37%), Gaps = 51/293 (17%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIP----PQS  282
            +D   IYG +      LR F  G+L         +P + + + ++   P        PQ 
Sbjct  173  LDGSAIYGSSHSWSDTLRSFSGGQLASG--PDPAFPRNSQNSLLMWMAPDPATGQGGPQG  230

Query  283  QMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKI  342
              A G +     P L     LW R HN     L  EHP WGDE+LFQ  R  +I     I
Sbjct  231  LYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNI  290

Query  343  VIEEYV--------QQLSGY--FLQLKFDPELLFGV-QF--------QYRNRIAMEFNHL  383
             + E++         +  GY  FL     PE +    QF         Y    +  F  +
Sbjct  291  AMYEWLPSFLKQTPPEYPGYHPFLDPSISPEFVVASEQFLSTMVPPGVYMRNASCHFQGI  350

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
             + +  +  + +V +  +S E    N  +     V+AL+   + QIA R       DH +
Sbjct  351  ANRNSSVSGALRVCNSYWSRE----NPKLQRAEDVDALLLGMASQIAER------EDHLV  400

Query  444  LHVAVD----------------VIRESREMRLQPFNEYRKRFGMKPYTSFQEL  480
            +    D                 ++  R++ L  + + R+  G+ P + +Q++
Sbjct  401  VEDVQDFWPGPLKFSRTDYLASCLQRGRDLGLPSYTKAREALGLPPVSHWQDI  453


>sp|P22079.2|PERL_HUMAN  RecName: Full=Lactoperoxidase; Short=LPO; AltName: Full=Salivary 
peroxidase; Short=SPO; Flags: Precursor
Length=712

 GENE ID: 4025 LPO | lactoperoxidase [Homo sapiens] (Over 10 PubMed links)

 Score = 52.8 bits (125),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 76/306 (24%), Positives = 121/306 (39%), Gaps = 49/306 (16%)

Query  302  TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD  361
            TL+LREHNR+   LK  +P W  E+L+Q  R IL      I   +Y+  L G  +Q    
Sbjct  384  TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP  443

Query  362  PELLFGVQFQYRNRIAMEFNHLYHW-HPLMPDS-FKVGSQ--------EYSYEQFLFNT-  410
            P    G       RI+  F   + + H  +P S F++           E       FNT 
Sbjct  444  P--YQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW  501

Query  411  SMLVDYGVEALVDAF----------SRQIAGRIGGGRNMDHHILH---VAVDVIRESREM  457
             M+ D G++ LV             ++ + G +        H +H   +A    +  R+ 
Sbjct  502  RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH  561

Query  458  RLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPN  514
                +N +R    +    + +EL   +  K +A +L  LYG  D ++ + G +       
Sbjct  562  GQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAI-------  614

Query  515  SIFGESMIEIG--APFSLKGLLGNPICS----PEYW--KPSTFGGEVGFNIVKTATLKKL  566
                E ++E G   P  L  LLG           +W   P  F  E   ++ K  +  +L
Sbjct  615  ---AEPLVERGRVGPL-LACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKM-SFSRL  669

Query  567  VCLNTK  572
            VC NT+
Sbjct  670  VCDNTR  675


>sp|A4IGL7.1|PXDN_XENTR  RecName: Full=Peroxidasin; Flags: Precursor
Length=1457

 GENE ID: 493201 pxdn | peroxidasin homolog [Xenopus (Silurana) tropicalis]
(10 or fewer PubMed links)

 Score = 52.4 bits (124),  Expect = 8e-06, Method: Compositional matrix adjust.
 Identities = 66/322 (20%), Positives = 131/322 (40%), Gaps = 45/322 (13%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
             GL    TLW REHNR+   L   +P W  + ++  TR I+  +   I    ++ ++ G  
Sbjct  972   GLTSMHTLWFREHNRIATELLRLNPHWDGDTIYHETRKIVGAQMQHITYSHWLPKIFGDV  1031

Query  356   -LQL-----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPL---MPDSFK-VGSQEYSYEQ  405
              +++      +DP +  G+  ++    A  F H    +P+   + + F+ +        +
Sbjct  1032  GMKMLGEYKSYDPNVNAGILNEFAT-AAFRFGHTL-INPILYRLDEKFEPIPQGHVPLHR  1089

Query  406   FLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHVAVD  449
               F+   +V+   E  +D   R + G     R               +M H + L +A  
Sbjct  1090  AFFSPFRIVN---EGGIDPLLRGLIGVAAKMRVTSQLLNTELTEKLFSMAHAVALDLAAL  1146

Query  450   VIRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGL  506
              ++  R+  + P++++R    +    +F +L  E    ++  +L+ LYG    ++ +P L
Sbjct  1147  NVQRGRDHGIPPYHDFRVFCNLSTVQTFDDLRNEIKNPDVREKLKRLYGSPLNIDLFPAL  1206

Query  507   LLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFNIVKTATLK  564
             ++E   P S  G +++ +     L     N      +W   P  F        +K  +L 
Sbjct  1207  MVEDLIPGSRLGPTLMCL-----LTTQFRNIRDGDRFWYENPGVFTA-AQLTQIKQTSLA  1260

Query  565   KLVCLNTKTCPYVS---FRVPD  583
             +++C N      V    FRV +
Sbjct  1261  RVLCDNGDNITKVQHDLFRVAE  1282


>sp|Q8HYB7.1|PERT_CANFA  RecName: Full=Thyroid peroxidase; Short=TPO; Flags: Precursor
Length=933

 GENE ID: 403521 TPO | thyroid peroxidase [Canis lupus familiaris]
(10 or fewer PubMed links)

 Score = 50.1 bits (118),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 90/413 (21%), Positives = 154/413 (37%), Gaps = 47/413 (11%)

Query  227  VDLGHIYGDN--LERQYQLRLFKDGKLKYQVLD---GEMYPPSVEEAPVLMHYP----RG  277
            +D   +YG +  LE+Q +     +G L+        G  + P +     L   P    RG
Sbjct  321  LDASTVYGSSPALEKQLRNWTSAEGLLRVNTRHWDAGRAHLPFMRPPAPLACVPEPGTRG  380

Query  278  IPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG  337
                     G      +P L    TLWLREHNR+   LKA +  W  +  +Q  R ++  
Sbjct  381  TAGAPCFLAGDSRASEVPTLAALHTLWLREHNRLASALKALNAHWSADTAYQEARKVVGA  440

Query  338  ETIKIVIEEYVQQLSG--YFLQ-----LKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
                I + +YV ++ G   F Q       +DP +   V   + +  A  F H    HPL+
Sbjct  441  LHQIITLRDYVPKVLGPEAFQQHVGPYEGYDPTMDPTVSNVF-STAAFRFGHAT-VHPLV  498

Query  391  PDSFKVGSQEYS-------YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
                    QE+         + F     +L + G++ L+       A      + M+  +
Sbjct  499  -RRLDARFQEHPGLPPLRLQDAFFSPWRLLKEGGLDPLLRGLLASPAKLPVQEQLMNEEL  557

Query  444  ------------LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAA  488
                        L +    ++  R+  L  +N +R+  G+    +  EL   V    +A 
Sbjct  558  TERLFVLGSSGSLDLGSINLQRGRDHGLPGYNAWREFCGLGRLHTRAELRSAVANATLAG  617

Query  489  ELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPST  548
             + +LYG  D ++ + G L E   P +  G  +        +K L         +W+ S 
Sbjct  618  RIMDLYGHPDNIDVWLGGLAEPLLPRARTGP-LFACLIGRQMKALRDG---DRFWWESSG  673

Query  549  FGGEVGFNIVKTATLKKLVCLNTK--TCPYVSFRVPDASQDDGPAVERPSTEL  599
               +     +   +L +++C NT   + P  +F+V    QD  P    P   L
Sbjct  674  VFTDEQRRELARHSLSRVICDNTGLPSVPADAFQVSRFPQDFEPCENIPGLNL  726


>sp|A8WQH2.1|PXDN_CAEBR  RecName: Full=Peroxidasin homolog; Flags: Precursor
Length=1288

 Score = 49.7 bits (117),  Expect = 5e-05, Method: Compositional matrix adjust.
 Identities = 86/396 (21%), Positives = 154/396 (38%), Gaps = 67/396 (16%)

Query  222   ALGHGVDLGHIYGDNLERQYQLR--LFKDGKLKYQVLD--GEMYPPS------------V  265
             AL   +D  ++YG N  +  +LR     +G+L+Y +    G+ Y P              
Sbjct  800   ALTSFLDASNVYGSNEVQAQELRDTYNNNGQLRYDITSAAGKEYLPFEKDSNMDCRRNFS  859

Query  266   EEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDE  325
             EE P+       +    Q+A           L    T+++REHNR+   LK  +  W  E
Sbjct  860   EENPIRCFLAGDLRANEQLA-----------LAATHTIFVREHNRIAKKLKKMNGNWDGE  908

Query  326   QLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLK--------FDPELLFGVQFQYRNRIA  377
              ++  TR I+      I  + ++  + G   Q+         +DP +   V   +    A
Sbjct  909   VIYHETRKIIGAMMQHITFKHWLPVVFGGQEQMDKFVGKYQGYDPAIDSSVTNAFAT-AA  967

Query  378   MEFNHLYHWHPLMPDSFKVGSQEYSYEQ--------FLFNTSMLVDYGVEALVDAF----  425
               F H      + P  F++G+   S +Q        F     +L + G++ L+       
Sbjct  968   FRFGHTI----INPTLFRLGNDFMSIKQGHIALHKAFFTPELVLTEGGIDPLLRGLFASP  1023

Query  426   ------SRQIAGRIGGGRNMDHH--ILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSF  477
                   ++ +   +     M  H   L +AV  I+ SR+  L  + EYR+   +     +
Sbjct  1024  LKHPMPTQLLNMELIEKLFMKGHEVSLDLAVMNIQRSRDHGLPSYTEYRQFCNLPVPARW  1083

Query  478   QELVG---EKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLL  534
             +++ G   +  +  +L  LYG    ++ + G ++E+   N +FG +   I      K   
Sbjct  1084  EDMKGYIKDDMIIQKLRGLYGVPQNIDLWVGGIVEEKLENGLFGPTFACIIGEQFRKMRD  1143

Query  535   GNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
             G+      Y K   F  E     +K  TL +L+C N
Sbjct  1144  GDRFW---YEKDGVFTPE-QMKEIKKVTLARLLCDN  1175


>sp|Q9VQH2.1|DUOX_DROME  RecName: Full=Dual oxidase
Length=1475

 Score = 48.9 bits (115),  Expect = 9e-05, Method: Compositional matrix adjust.
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)

Query  247  KDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLR  306
            KDGKL   V +    P      P +M   + + P+    +G       P ++ +A L+LR
Sbjct  178  KDGKLP--VRNTMRVPLFNNPVPSVM---KMLSPERLFLLGDPRTNQNPAILSFAILFLR  232

Query  307  EHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG  353
             HN +   +K  HP W DE ++Q  R  +I     +++ EY+    G
Sbjct  233  WHNTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFLG  279


>sp|Q9ES45.1|DUOX2_RAT  RecName: Full=Dual oxidase 2; AltName: Full=NADH/NADPH thyroid 
oxidase THOX2; AltName: Full=Large NOX 2; AltName: Full=Long 
NOX 2; AltName: Full=Thyroid oxidase 2; Flags: Precursor
Length=1517

 GENE ID: 79107 Duox2 | dual oxidase 2 [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 48.5 bits (114),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 6/126 (4%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIP----PQS  282
            +D   IYG +      LR F  G+L         +P + + + ++   P        PQ 
Sbjct  179  LDGSAIYGSSHSWSDTLRSFSGGQLASG--PDPAFPRNSQNSLLMWMAPDPATGQGGPQG  236

Query  283  QMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKI  342
              A G +     P L     LW R HN     L  EHP WGDE+LFQ  R  +I     I
Sbjct  237  LYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNI  296

Query  343  VIEEYV  348
             + +++
Sbjct  297  ALYQWL  302


>sp|Q9NRD9.1|DUOX1_HUMAN  RecName: Full=Dual oxidase 1; AltName: Full=NADPH thyroid oxidase 
1; AltName: Full=Large NOX 1; AltName: Full=Long NOX 1; 
AltName: Full=Thyroid oxidase 1; Flags: Precursor
Length=1551

 GENE ID: 53905 DUOX1 | dual oxidase 1 [Homo sapiens] (Over 10 PubMed links)

 Score = 48.1 bits (113),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 70/301 (23%), Positives = 114/301 (37%), Gaps = 67/301 (22%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLM----------HYPR  276
            +D   IYG +      LR F  G+L       +   P   + P+LM          + PR
Sbjct  173  LDGSAIYGSSHSWSDALRSFSRGQLAS---GPDPAFPRDSQNPLLMWAAPDPATGQNGPR  229

Query  277  GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI  336
            G+      A G E     P L     LW R HN     L  +HP W DE+LFQ  R  +I
Sbjct  230  GL-----YAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVI  284

Query  337  GETIKIVIEEY--------VQQLSGY--FLQLKFDPELLFGV-QF--------QYRNRIA  377
                 I + E+        + + +GY  FL      E +    QF         Y    +
Sbjct  285  ATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNAS  344

Query  378  MEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR  437
              F  + + +  +  + +V +  +S E    + S+     V+AL+   + QIA R     
Sbjct  345  CHFQGVINRNSSVSRALRVCNSYWSRE----HPSLQSAEDVDALLLGMASQIAER-----  395

Query  438  NMDHHIL------------------HVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQE  479
              + H+L                  H+A   ++  R++ L  + + R   G+ P T +Q+
Sbjct  396  --EDHVLVEDVRDFWPGPLKFSRTDHLA-SCLQRGRDLGLPSYTKARAALGLSPITRWQD  452

Query  480  L  480
            +
Sbjct  453  I  453


>sp|P09933.1|PERT_PIG  RecName: Full=Thyroid peroxidase; Short=TPO; Flags: Precursor
Length=926

 GENE ID: 445522 TPO | thyroid peroxidase [Sus scrofa]
(10 or fewer PubMed links)

 Score = 47.0 bits (110),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 57/253 (22%), Positives = 99/253 (39%), Gaps = 31/253 (12%)

Query  294  LPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG  353
            +PGL    TLWLREHNR+    KA +  W  + ++Q  R ++      + + +YV ++ G
Sbjct  399  VPGLTALHTLWLREHNRLAAAFKALNAHWSADTVYQEARKVVGALHQIVTLRDYVPKILG  458

Query  354  --YFLQ-----LKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQF  406
               F Q       +DP +   V   + +  A  F H    HPL+        QE+     
Sbjct  459  AEAFGQHVGPYQGYDPAVDPTVSNVF-STAAFRFGHAT-IHPLV-RRLDARFQEHPGSHL  515

Query  407  LFNTSMLVDYGV--EALVDAFSRQIAGRIGGGRNMDHHI----------------LHVAV  448
                +    + +  E  VD   R +  R    +  D  +                L +A 
Sbjct  516  PLRAAFFQPWRLLREGGVDPVLRGLLARPAKLQVQDQLMNEELTERLFVLSNSGTLDLAS  575

Query  449  DVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPG  505
              ++  R+  L  +NE+R+  G+    ++ +L        +A  +  LY   D ++ + G
Sbjct  576  INLQRGRDHGLPGYNEWREFCGLSRLETWADLSAATANGRVADRILGLYQHPDNIDVWLG  635

Query  506  LLLEKCHPNSIFG  518
             L E   P +  G
Sbjct  636  GLAESFLPGARTG  648


>sp|P05164.1|PERM_HUMAN  RecName: Full=Myeloperoxidase; Short=MPO; Contains: RecName: 
Full=89 kDa myeloperoxidase; Contains: RecName: Full=84 kDa 
myeloperoxidase; Contains: RecName: Full=Myeloperoxidase light 
chain; Contains: RecName: Full=Myeloperoxidase heavy chain; 
Flags: Precursor
Length=745

 GENE ID: 4353 MPO | myeloperoxidase [Homo sapiens] (Over 100 PubMed links)

 Score = 45.8 bits (107),  Expect = 6e-04, Method: Compositional matrix adjust.
 Identities = 57/246 (23%), Positives = 114/246 (46%), Gaps = 43/246 (17%)

Query  294  LPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVI-EEYVQQLS  352
            +P L    TL LREHNR+   LK+ +P W  E+L+Q  R I +G  ++I+   +Y+  + 
Sbjct  409  MPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKI-VGAMVQIITYRDYLPLVL  467

Query  353  GYFLQLKFDPELLFGVQFQYRN-------RIAMEFNHLYHW-HPLM-PDSFKVGSQEYSY  403
            G     K+ P         YR+       RIA  F + + + H L+ P  F++ ++    
Sbjct  468  GPTAMRKYLPT--------YRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPM  519

Query  404  EQ---------FLFNTSMLVDYGVEALVDA-------FSRQIAGRIGGGR-NMDHHILHV  446
            E          F  +  ++++ G++ ++          +RQ    +   R  +   ++ +
Sbjct  520  EPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRI  579

Query  447  AVDV----IRESREMRLQPFNEYRKRFGM-KPYTSFQ--ELVGEKEMAAELEELYGDIDA  499
             +D+    ++ SR+  L  +N +R+  G+ +P T  Q   ++   ++A +L E YG  + 
Sbjct  580  GLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNN  639

Query  500  LEFYPG  505
            ++ + G
Sbjct  640  IDIWMG  645


>sp|Q9NRD8.1|DUOX2_HUMAN  RecName: Full=Dual oxidase 2; AltName: Full=NADPH oxidase/peroxidase 
DUOX2; AltName: Full=NADPH thyroid oxidase 2; AltName: 
Full=Large NOX 2; AltName: Full=Long NOX 2; AltName: Full=Thyroid 
oxidase 2; AltName: Full=NADH/NADPH thyroid oxidase 
p138-tox; AltName: Full=p138 thyroid oxidase; Flags: Precursor
Length=1548

 GENE ID: 50506 DUOX2 | dual oxidase 2 [Homo sapiens] (Over 10 PubMed links)

 Score = 45.4 bits (106),  Expect = 8e-04, Method: Compositional matrix adjust.
 Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 18/132 (13%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLM----------HYPR  276
            +D   IYG +      LR F  G+L       +   P   + P+LM          + PR
Sbjct  179  LDGSAIYGSSHSWSDALRSFSGGQLAS---GPDPAFPRDSQNPLLMWAAPDPATGQNGPR  235

Query  277  GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI  336
            G+      A G E     P L     LW R HN     L  +HP W DE+LFQ  R  +I
Sbjct  236  GL-----YAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVI  290

Query  337  GETIKIVIEEYV  348
                 I + E++
Sbjct  291  ATYQNIAVYEWL  302


>sp|Q9DDD0.1|NRX1A_CHICK  RecName: Full=Neurexin-1-alpha; AltName: Full=Neurexin I-alpha
Length=1363

 GENE ID: 395398 NRXN1 | neurexin 1 [Gallus gallus] (10 or fewer PubMed links)

 Score = 45.4 bits (106),  Expect = 9e-04, Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query  34   PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            PC   PC++ G+C R G +RY CDC+ TGY G +C
Sbjct  535  PCLSNPCKNNGVC-RDGWNRYVCDCSGTGYLGRSC  568


 Score = 42.0 bits (97),  Expect = 0.009, Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query  27   GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG  72
            G   P   C    C +QG+C++   D + CDC+ T +SGP C  PG
Sbjct  935  GCEGPSTTCQEDSCANQGVCLQ-QWDGFSCDCSMTSFSGPLCNDPG  979


>sp|Q1ENI8.1|PXDN_CAEEL  RecName: Full=Peroxidasin homolog; Flags: Precursor
Length=1285

 GENE ID: 191484 pxn-1 | PeroXidasiN (Drosophila peroxidase) homolog
[Caenorhabditis elegans] (10 or fewer PubMed links)

 Score = 45.4 bits (106),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 85/397 (21%), Positives = 152/397 (38%), Gaps = 67/397 (16%)

Query  221   KALGHGVDLGHIYGDNLERQYQLR--LFKDGKLKYQVLD--GEMYPPS------------  264
              AL   +D  ++YG N  +  +LR     +G L++ +    G+ Y P             
Sbjct  800   NALTSFLDASNVYGSNEVQAQELRDTYNNNGMLRFDITSEAGKEYLPFEKDSNMDCRRNF  859

Query  265   VEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGD  324
              EE P+       +    Q+A           L    T+++REHNR+   LK+ +  W  
Sbjct  860   SEENPIRCFLAGDLRANEQLA-----------LAATHTIFIREHNRIAKKLKSMNGNWDG  908

Query  325   EQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLK--------FDPELLFGVQFQYRNRI  376
             E ++  TR I+      I  + ++  + G   Q+         +DP++   V   +    
Sbjct  909   EIIYHETRKIVGAMMQHITYKHWMPIIFGGQAQMNKFVGTYQGYDPDVDASVTNAFAT-A  967

Query  377   AMEFNHLYHWHPLMPDSFKVGS--------QEYSYEQFLFNTSMLVDYGVEALVDAF---  425
             A  F H      + P  F++G+            ++ F     +L   GV+ L+      
Sbjct  968   AFRFGHTI----INPSLFRLGNDFMPIKEGHIALHKAFFTPELVLTQGGVDPLLRGLFAS  1023

Query  426   -------SRQIAGRIGGGRNMDHH--ILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTS  476
                    ++ +   +     M  H   L +AV  I+ SR+  L  + EYRK   +     
Sbjct  1024  PLKHPMPTQLLNMELIEKLFMKGHEVSLDLAVMNIQRSRDHGLPSYTEYRKFCNLPVPVQ  1083

Query  477   FQELVG---EKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGL  533
             ++++ G   +  +  +L  LYG    ++ + G ++E+   N +FG +   I      K  
Sbjct  1084  WEDMKGYIKDDMIIQKLRGLYGVPQNIDLWVGGIVEEKLENGLFGPTFACIIGEQFRKIR  1143

Query  534   LGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              G+      Y K   F  E     +K  TL +L C N
Sbjct  1144  DGDRFW---YEKDGVFTPE-QLREIKKITLARLFCDN  1176


>sp|Q63372.3|NRX1A_RAT  RecName: Full=Neurexin-1-alpha; AltName: Full=Neurexin I-alpha; 
Flags: Precursor
Length=1530

 GENE ID: 60391 Nrxn1 | neurexin 1 [Rattus norvegicus] (Over 10 PubMed links)

 Score = 45.1 bits (105),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query  34   PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            PC   PC++ G+C R G +RY CDC+ TGY G +C
Sbjct  702  PCLSNPCKNNGMC-RDGWNRYVCDCSGTGYLGRSC  735


 Score = 42.4 bits (98),  Expect = 0.007, Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query  27    GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG  72
             G   P   C    C +QG+C++   D + CDC+ T +SGP C  PG
Sbjct  1102  GCEGPSTTCQEDSCSNQGVCLQ-QWDGFSCDCSMTSFSGPLCNDPG  1146


 Score = 32.7 bits (73),  Expect = 6.5, Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 5/42 (11%)

Query  33   NPCCYYPCQHQGICVRFGL-----DRYQCDCTRTGYSGPNCT  69
            +PC        G+C+  G+     D+  CDC+RTG+ G +C+
Sbjct  215  SPCEAGDEGDGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCS  256


>sp|Q9CS84.3|NRX1A_MOUSE  RecName: Full=Neurexin-1-alpha; AltName: Full=Neurexin I-alpha; 
Flags: Precursor
Length=1514

 GENE ID: 18189 Nrxn1 | neurexin I [Mus musculus] (Over 10 PubMed links)

 Score = 44.7 bits (104),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query  34   PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            PC   PC++ G+C R G +RY CDC+ TGY G +C
Sbjct  686  PCLSNPCKNNGMC-RDGWNRYVCDCSGTGYLGRSC  719


 Score = 42.4 bits (98),  Expect = 0.007, Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query  27    GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG  72
             G   P   C    C +QG+C++   D + CDC+ T +SGP C  PG
Sbjct  1086  GCEGPSTTCQEDSCSNQGVCLQ-QWDGFSCDCSMTSFSGPLCNDPG  1130


 Score = 32.3 bits (72),  Expect = 8.5, Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 5/42 (11%)

Query  33   NPCCYYPCQHQGICVRFGL-----DRYQCDCTRTGYSGPNCT  69
            +PC        G+C+  G+     D+  CDC+RTG+ G +C+
Sbjct  215  SPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCS  256


>sp|Q28146.1|NRX1A_BOVIN  RecName: Full=Neurexin-1-alpha; AltName: Full=Neurexin I-alpha; 
Flags: Precursor
Length=1530

 GENE ID: 281950 NRXN1 | neurexin 1 [Bos taurus] (10 or fewer PubMed links)

 Score = 44.7 bits (104),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query  34   PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            PC   PC++ G+C R G +RY CDC+ TGY G +C
Sbjct  702  PCLSNPCKNNGMC-RDGWNRYVCDCSGTGYLGRSC  735


 Score = 40.8 bits (94),  Expect = 0.021, Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query  27    GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG  72
             G   P   C    C +QG+C++   D   CDC+ T +SGP C  PG
Sbjct  1102  GCEGPSTTCQEDSCSNQGVCLQ-QWDGISCDCSMTSFSGPLCNDPG  1146


 Score = 32.3 bits (72),  Expect = 8.9, Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 19/30 (63%), Gaps = 1/30 (3%)

Query  40   CQHQGICVRFGLDRYQCDCTRTGYSGPNCT  69
            C + G+C     D+  CDC+RTG+ G +C+
Sbjct  228  CLNGGVCSVVD-DQAVCDCSRTGFRGKDCS  256


>sp|Q9ULB1.1|NRX1A_HUMAN  RecName: Full=Neurexin-1-alpha; AltName: Full=Neurexin I-alpha; 
Flags: Precursor
Length=1477

 GENE ID: 9378 NRXN1 | neurexin 1 [Homo sapiens] (Over 10 PubMed links)

 Score = 44.7 bits (104),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query  34   PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            PC   PC++ G+C R G +RY CDC+ TGY G +C
Sbjct  679  PCLSNPCKNNGMC-RDGWNRYVCDCSGTGYLGRSC  712


 Score = 42.4 bits (98),  Expect = 0.008, Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query  27    GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG  72
             G   P   C    C +QG+C++   D + CDC+ T +SGP C  PG
Sbjct  1079  GCEGPSTTCQEDSCSNQGVCLQ-QWDGFSCDCSMTSFSGPLCNDPG  1123


 Score = 32.0 bits (71),  Expect = 9.4, Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 19/30 (63%), Gaps = 1/30 (3%)

Query  40   CQHQGICVRFGLDRYQCDCTRTGYSGPNCT  69
            C + G+C     D+  CDC+RTG+ G +C+
Sbjct  228  CLNGGVCSVVD-DQAVCDCSRTGFRGKDCS  256


>sp|Q9P2S2.1|NRX2A_HUMAN  RecName: Full=Neurexin-2-alpha; AltName: Full=Neurexin II-alpha; 
Flags: Precursor
Length=1712

 GENE ID: 9379 NRXN2 | neurexin 2 [Homo sapiens] (Over 10 PubMed links)

 Score = 43.9 bits (102),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query  27    GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG  72
             G   P   C    C +QG+C++   D + CDCT T Y GP C  PG
Sbjct  1092  GCDGPSTTCTEESCANQGVCLQ-QWDGFTCDCTMTSYGGPVCNDPG  1136


 Score = 37.4 bits (85),  Expect = 0.22, Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query  35   CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            C   PC++ G+C R G +R+ CDC  TG+ G  C
Sbjct  694  CASAPCRNGGVC-REGWNRFICDCIGTGFLGRVC  726


 Score = 33.1 bits (74),  Expect = 5.1, Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 19/41 (46%), Gaps = 3/41 (7%)

Query  32   VNPCCY---YPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT  69
             +P C     PC + G+C         CDC+ TG+ G  C+
Sbjct  202  ADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCS  242


>sp|Q63374.3|NRX2A_RAT  RecName: Full=Neurexin-2-alpha; AltName: Full=Neurexin II-alpha; 
Flags: Precursor
Length=1715

 GENE ID: 116595 Nrxn2 | neurexin 2 [Rattus norvegicus] (Over 10 PubMed links)

 Score = 43.9 bits (102),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query  27    GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG  72
             G   P   C    C +QG+C++   D + CDCT T Y GP C  PG
Sbjct  1095  GCDGPSTTCTEESCANQGVCLQ-QWDGFTCDCTMTSYGGPVCNDPG  1139


 Score = 38.5 bits (88),  Expect = 0.12, Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query  35   CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            C   PC++ GIC R G +R+ CDC  TG+ G  C
Sbjct  694  CASAPCRNGGIC-REGWNRFVCDCIGTGFLGRVC  726


 Score = 33.1 bits (74),  Expect = 4.4, Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 19/42 (45%), Gaps = 0/42 (0%)

Query  28   APTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT  69
            A  P+      PC + G+C         CDC+ TG+ G  C+
Sbjct  201  AADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCS  242


>sp|P11678.2|PERE_HUMAN  RecName: Full=Eosinophil peroxidase; Short=EPO; Contains: RecName: 
Full=Eosinophil peroxidase light chain; Contains: RecName: 
Full=Eosinophil peroxidase heavy chain; Flags: Precursor
Length=715

 GENE ID: 8288 EPX | eosinophil peroxidase [Homo sapiens] (Over 10 PubMed links)

 Score = 43.5 bits (101),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 52/257 (20%), Positives = 105/257 (40%), Gaps = 41/257 (15%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY  354
            P L    TL++REHNR+   L+  +P W  ++L+   R I+ G  ++I+           
Sbjct  382  PKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIM-GAMVQIITYR-------D  433

Query  355  FLQLKFDPELLFGVQFQYRN-------RIAMEFNHLYHWHPLM--PDSFKVGSQEYS---  402
            FL L             YR        R+A  F   + +   M  P  F++ SQ  +   
Sbjct  434  FLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAP  493

Query  403  ------YEQFLFNTSMLVDYGVEALVDA-------FSRQIAGRIGGGRN-MDHHILHVAV  448
                     F  +  ++ + G++ ++          +RQ A  +   R+ +   +  + +
Sbjct  494  NSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGL  553

Query  449  DV----IRESREMRLQPFNEYRKRFGM---KPYTSFQELVGEKEMAAELEELYGDIDALE  501
            D+    ++ SR+  L  +N +R+  G+   +       ++  +++A +   LYG  D ++
Sbjct  554  DLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNID  613

Query  502  FYPGLLLEKCHPNSIFG  518
             + G + E   P +  G
Sbjct  614  IWIGAIAEPLLPGARVG  630


>sp|P80025.1|PERL_BOVIN  RecName: Full=Lactoperoxidase; Short=LPO; Flags: Precursor
Length=712

 GENE ID: 280844 LPO | lactoperoxidase [Bos taurus] (10 or fewer PubMed links)

 Score = 43.1 bits (100),  Expect = 0.005, Method: Compositional matrix adjust.
 Identities = 50/227 (22%), Positives = 88/227 (38%), Gaps = 29/227 (12%)

Query  306  REHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELL  365
            REHNR+   LK  +P W  E+L+Q  R IL      I   +Y+  + G  +Q    P   
Sbjct  388  REHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPP--Y  445

Query  366  FGVQFQYRNRIAMEFNHLYHW-HPLMPDSFKVGSQEYS---------YEQFLFNTSMLV-  414
             G       RI+  F   + + H  +P +     + Y               FNT  ++ 
Sbjct  446  QGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIK  505

Query  415  DYGVEALVDAF----------SRQIAGRIGGGRNMDHHILH---VAVDVIRESREMRLQP  461
            D G++ LV              + +   +        H +H   +A   ++  R+  +  
Sbjct  506  DGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPG  565

Query  462  FNEYRKRFGM---KPYTSFQELVGEKEMAAELEELYGDIDALEFYPG  505
            +N +R   G+   K     Q ++  K +A +L +LY   D ++ + G
Sbjct  566  YNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIG  612


>sp|Q07310.1|NRX3A_RAT  RecName: Full=Neurexin-3-alpha; AltName: Full=Neurexin III-alpha; 
Flags: Precursor
Length=1578

 GENE ID: 116508 Nrxn3 | neurexin 3 [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 43.1 bits (100),  Expect = 0.005, Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 14/72 (19%)

Query  25    DPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG------------  72
             D G   P   C    C +QG+C++   + + CDC+ T YSG  C  PG            
Sbjct  1047  DRGCEGPSTTCQEDSCANQGVCMQ-QWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLI  1105

Query  73    LWTWLRNSLRPS  84
             L+TW  N  RPS
Sbjct  1106  LYTWPAND-RPS  1116


 Score = 41.2 bits (95),  Expect = 0.018, Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query  35   CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            C  YPC++  +C + G +R+ CDCT TGY G  C
Sbjct  651  CDSYPCKNNAVC-KDGWNRFICDCTGTGYWGRTC  683


 Score = 38.9 bits (89),  Expect = 0.088, Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 12/62 (19%)

Query  34   PCCYYPCQHQGICVRFGLDRY-QCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            PC   PC++ GIC  F LD +  CDC+ TGY G  C+           +   P  +H ++
Sbjct  201  PCGERPCENGGIC--FLLDGHPTCDCSTTGYGGTLCS---------EDVSQGPGLSHLMM  249

Query  93   TH  94
            + 
Sbjct  250  SE  251


>sp|P07202.4|PERT_HUMAN  RecName: Full=Thyroid peroxidase; Short=TPO; Flags: Precursor
Length=933

 GENE ID: 7173 TPO | thyroid peroxidase [Homo sapiens] (Over 10 PubMed links)

 Score = 41.6 bits (96),  Expect = 0.014, Method: Compositional matrix adjust.
 Identities = 74/330 (22%), Positives = 132/330 (40%), Gaps = 41/330 (12%)

Query  227  VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVEEAPVLMHYPR-GIPP  280
            +D   +YG +  LERQ +     +G L+        G  Y P V         P  GIP 
Sbjct  324  LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG  383

Query  281  QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG  337
            +++      G      +P L    TLWLREHNR+   LKA +  W  + ++Q  R ++  
Sbjct  384  ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA  443

Query  338  ETIKIVIEEYVQQLSG--YFLQL-----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
                I + +Y+ ++ G   F Q       +D      V   + +  A  F H    HPL+
Sbjct  444  LHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVF-STAAFRFGHAT-IHPLV  501

Query  391  PDSFKVGSQEYS-------YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
                    QE+        ++ F    ++L   G++ L+     + A      + M+  +
Sbjct  502  -RRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEEL  560

Query  444  ------------LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAA  488
                        L +A   ++  R+  L  +NE+R+  G+    +  +L   +  + +A 
Sbjct  561  TERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVAD  620

Query  489  ELEELYGDIDALEFYPGLLLEKCHPNSIFG  518
            ++ +LY   D ++ + G L E   P +  G
Sbjct  621  KILDLYKHPDNIDVWLGGLAENFLPRARTG  650


>sp|Q19319.2|CADH4_CAEEL  RecName: Full=Cadherin-4; Flags: Precursor
Length=4307

 GENE ID: 175590 cdh-4 | CaDHerin family [Caenorhabditis elegans]
(10 or fewer PubMed links)

 Score = 41.6 bits (96),  Expect = 0.014, Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query  24    ADPG-APTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
             A PG +    +PC   PCQH G C+  G   ++C+C  + YSG  C I
Sbjct  3900  AQPGCSALTSSPCNDLPCQHAGTCISQGKSHFKCECP-SRYSGNVCEI  3946


>sp|Q9Y4C0.3|NRX3A_HUMAN  RecName: Full=Neurexin-3-alpha; AltName: Full=Neurexin III-alpha; 
Flags: Precursor
Length=1643

 GENE ID: 9369 NRXN3 | neurexin 3 [Homo sapiens] (Over 10 PubMed links)

 Score = 41.2 bits (95),  Expect = 0.016, Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 14/70 (20%)

Query  27    GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG------------LW  74
             G   P   C    C +QG+C++   + + CDC+ T YSG  C  PG            L+
Sbjct  1045  GCEGPSTTCQEDSCANQGVCMQ-QWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILY  1103

Query  75    TWLRNSLRPS  84
             TW  N  RPS
Sbjct  1104  TWPAND-RPS  1112


 Score = 41.2 bits (95),  Expect = 0.018, Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query  35   CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            C  YPC++  +C + G +R+ CDCT TGY G  C
Sbjct  647  CDSYPCKNNAVC-KDGWNRFICDCTGTGYWGRTC  679


 Score = 38.9 bits (89),  Expect = 0.080, Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 12/62 (19%)

Query  34   PCCYYPCQHQGICVRFGLDRY-QCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            PC   PC++ GIC  F LD +  CDC+ TGY G  C+           +   P  +H ++
Sbjct  201  PCGERPCENGGIC--FLLDGHPTCDCSTTGYGGKLCS---------EDVSQDPGLSHLMM  249

Query  93   TH  94
            + 
Sbjct  250  SE  251


>sp|O57409.1|DLLB_DANRE  RecName: Full=Delta-like protein B; Short=DeltaB; Flags: Precursor
Length=615

 GENE ID: 30141 dlb | deltaB [Danio rerio] (Over 10 PubMed links)

 Score = 40.0 bits (92),  Expect = 0.039, Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 2/61 (3%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTH  89
            T ++ C  YPCQ+ G C + G++ Y C CT  G++G NC++          L     FTH
Sbjct  424  TNIDDCARYPCQNAGTC-QDGINDYTCTCT-LGFTGKNCSLRADACLTNPCLHGGTCFTH  481

Query  90   F  90
            F
Sbjct  482  F  482


>sp|Q8VHS2.2|CRUM1_MOUSE  RecName: Full=Crumbs homolog 1; Flags: Precursor
Length=1405

 GENE ID: 170788 Crb1 | crumbs homolog 1 (Drosophila) [Mus musculus]
(Over 10 PubMed links)

 Score = 39.7 bits (91),  Expect = 0.047, Method: Compositional matrix adjust.
 Identities = 21/46 (45%), Positives = 28/46 (60%), Gaps = 3/46 (6%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT--IPGLWT  75
            VN C   PC H G+CV  G + Y CDCT +G++G +C   IP  W+
Sbjct  262  VNECESQPCLHGGLCVD-GRNSYHCDCTGSGFTGMHCESLIPLCWS  306


>sp|P07207.3|NOTCH_DROME  RecName: Full=Neurogenic locus Notch protein; Contains: RecName: 
Full=Processed neurogenic locus Notch protein; Flags: Precursor
Length=2703

 Score = 39.7 bits (91),  Expect = 0.049, Method: Composition-based stats.
 Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            T   PC   PCQ+ GIC   GL  Y+C C + G+ G NC
Sbjct  254  TKYKPCSPSPCQNGGICRSNGLS-YECKCPK-GFEGKNC  290


 Score = 37.0 bits (84),  Expect = 0.36, Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 21/30 (70%), Gaps = 2/30 (6%)

Query  39   PCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            PC+H GICV      Y+C+C++ G++GP C
Sbjct  458  PCEHNGICVNTP-GSYRCNCSQ-GFTGPRC  485


 Score = 35.0 bits (79),  Expect = 1.4, Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query  30    TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
             T +N C   PCQ+   C ++ ++ Y C C   G+SG NC
Sbjct  983   TDINECLSQPCQNGATCSQY-VNSYTCTCP-LGFSGINC  1019


 Score = 33.1 bits (74),  Expect = 5.2, Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            ++ C   PCQH G C    L+ + C C   GY+G  C
Sbjct  792  IDECSSNPCQHGGTCYD-KLNAFSCQCM-PGYTGQKC  826


 Score = 32.3 bits (72),  Expect = 9.0, Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 8/48 (16%)

Query  26   PGAPTPVNPCCYYPCQHQGICVRFGLD---RYQCDCTRTGYSGPNCTI  70
            P   T +N C  +PCQ++G C    LD    ++C C   G++G  C I
Sbjct  483  PRCETNINECESHPCQNEGSC----LDDPGTFRCVCM-PGFTGTQCEI  525


 Score = 32.0 bits (71),  Expect = 9.7, Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            ++ C   PC+++GIC    +  Y C+C   GY+G +C I
Sbjct  565  IDDCQSQPCRNRGIC-HDSIAGYSCECP-PGYTGTSCEI  601


>sp|Q04721.3|NOTC2_HUMAN  RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 
2; Short=hN2; Contains: RecName: Full=Notch 2 extracellular 
truncation; Contains: RecName: Full=Notch 2 intracellular 
domain; Flags: Precursor
Length=2471

 GENE ID: 4853 NOTCH2 | Notch homolog 2 (Drosophila) [Homo sapiens]
(Over 10 PubMed links)

 Score = 39.7 bits (91),  Expect = 0.054, Method: Composition-based stats.
 Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 2/37 (5%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
             +N C  +PC ++G CV  GL  Y+C C   GY+G NC
Sbjct  1026  INECSSHPCLNEGTCVD-GLGTYRCSCP-LGYTGKNC  1060


 Score = 34.3 bits (77),  Expect = 1.9, Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
             ++ C   PCQH   C  F +  Y+C+C   GY G NC
Sbjct  1150  LDECASNPCQHGATCSDF-IGGYRCECV-PGYQGVNC  1184


 Score = 33.9 bits (76),  Expect = 2.7, Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            +N C   PC + G CV   ++R+QC C   G++GP C I
Sbjct  495  INECQSNPCVNNGQCVD-KVNRFQCLCP-PGFTGPVCQI  531


 Score = 33.5 bits (75),  Expect = 4.0, Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 2/44 (4%)

Query  30    TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGL  73
             T VN C   PC+++G CV+   +  QC C  +G++G  C +P +
Sbjct  1062  TLVNLCSRSPCKNKGTCVQKKAES-QCLCP-SGWAGAYCDVPNV  1103


 Score = 32.3 bits (72),  Expect = 7.6, Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 2/32 (6%)

Query  39   PCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            PC+H G CV      + C+C + GY+GP C +
Sbjct  426  PCEHAGKCVNTD-GAFHCECLK-GYAGPRCEM  455


 Score = 32.3 bits (72),  Expect = 8.6, Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            N C   PCQ+ G C    ++ Y+C C + G+ G NC +
Sbjct  759  NECLSNPCQNGGTCDNL-VNGYRCTC-KKGFKGYNCQV  794


>sp|Q9QXX0.1|JAG1_MOUSE  RecName: Full=Protein jagged-1; Short=Jagged1; AltName: CD_antigen=CD339; 
Flags: Precursor
Length=1218

 GENE ID: 16449 Jag1 | jagged 1 [Mus musculus] (Over 100 PubMed links)

 Score = 38.9 bits (89),  Expect = 0.079, Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query  37   YYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            + PC ++G C   G D+YQC C   GYSGPNC I
Sbjct  303  HQPCLNRGTCSNTGPDKYQCSCPE-GYSGPNCEI  335


>sp|Q63722.2|JAG1_RAT  RecName: Full=Protein jagged-1; Short=Jagged1; AltName: CD_antigen=CD339; 
Flags: Precursor
Length=1219

 GENE ID: 29146 Jag1 | jagged 1 [Rattus norvegicus] (Over 10 PubMed links)

 Score = 38.9 bits (89),  Expect = 0.081, Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query  37   YYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            + PC ++G C   G D+YQC C   GYSGPNC I
Sbjct  303  HQPCLNRGTCSNTGPDKYQCSCPE-GYSGPNCEI  335


>sp|P46530.1|NOTC1_DANRE  RecName: Full=Neurogenic locus notch homolog protein 1; Flags: 
Precursor
Length=2437

 GENE ID: 30718 notch1a | notch homolog 1a [Danio rerio] (Over 10 PubMed links)

 Score = 38.5 bits (88),  Expect = 0.10, Method: Composition-based stats.
 Identities = 34/116 (29%), Positives = 48/116 (41%), Gaps = 13/116 (11%)

Query  30   TPVNPCCY-YPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI--PGLWTWLRNSLRPSPS  86
            TPVN  C   PC++ G C    LD + C C + G+SG  C +  P       N  + S  
Sbjct  99   TPVNHACMNSPCRNGGTCSLLTLDTFTCRC-QPGWSGKTCQLADPCASNPCANGGQCSAF  157

Query  87   FTHFLLT-----HGRWFWEFVNATFIREMLMR----LVLTVRSNLIPSPPTYNSAH  133
             +H++ T     HG+   + VN   +     R     +  V S L   PP Y   H
Sbjct  158  ESHYICTCPPNFHGQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCPPEYTGPH  213


 Score = 34.7 bits (78),  Expect = 1.6, Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
             +N C   PCQ+ G C+   ++ Y+C C R G  G +C I
Sbjct  1182  INECLSQPCQNGGTCIDL-VNTYKCSCPR-GTQGVHCEI  1218


 Score = 34.3 bits (77),  Expect = 1.9, Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 2/39 (5%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            +N C   PC + G C       Y C C R G+SGPNC +
Sbjct  752  INECLSNPCVNGGTCKDM-TSGYLCTC-RAGFSGPNCQM  788


 Score = 34.3 bits (77),  Expect = 2.2, Method: Composition-based stats.
 Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 2/37 (5%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
             VN C   PCQ+ G C + G   Y+C C   GY+G NC
Sbjct  1020  VNECDSRPCQNGGSC-QDGYGTYKCTCPH-GYTGLNC  1054


>sp|P10040.3|CRB_DROME  RecName: Full=Protein crumbs; AltName: Full=95F; Flags: Precursor
Length=2146

 Score = 38.5 bits (88),  Expect = 0.10, Method: Composition-based stats.
 Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
             +N C   PCQ+ G C    + RY+CDC  TG+ G  C
Sbjct  1951  INECESNPCQNGGQCKDL-VGRYECDCQGTGFEGIRC  1986


 Score = 37.7 bits (86),  Expect = 0.20, Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 22/36 (61%), Gaps = 1/36 (2%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            + C   PCQ+ G C+   ++ + CDC+ TGY+G  C
Sbjct  388  DECASQPCQNNGSCID-RINGFSCDCSGTGYTGAFC  422


 Score = 37.4 bits (85),  Expect = 0.23, Method: Composition-based stats.
 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            N C   PCQ+ G CV      Y+C CTR G++G  C
Sbjct  609  NQCATQPCQNGGECVDLPNGDYECKCTR-GWTGRTC  643


 Score = 37.0 bits (84),  Expect = 0.34, Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            ++ C   PC + G C+   L  ++CDC+ TGY G NC +
Sbjct  762  IDDCVGDPCLNGGQCID-QLGGFRCDCSGTGYEGENCEL  799


>sp|P49290.1|PERE_MOUSE  RecName: Full=Eosinophil peroxidase; Short=EPO; Contains: RecName: 
Full=Eosinophil peroxidase light chain; Contains: RecName: 
Full=Eosinophil peroxidase heavy chain; Flags: Precursor
Length=716

 GENE ID: 13861 Epx | eosinophil peroxidase [Mus musculus]
(Over 10 PubMed links)

 Score = 38.5 bits (88),  Expect = 0.11, Method: Compositional matrix adjust.
 Identities = 62/317 (19%), Positives = 120/317 (37%), Gaps = 59/317 (18%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIV-----------  343
            P L    TL++REHNR+   L+  +P W  ++L+   R I +G  ++I+           
Sbjct  383  PKLTALHTLFVREHNRLAAELRRLNPHWSGDKLYNEARKI-VGAMVQIITYRDFLPLVLG  441

Query  344  ---IEEYVQQLSGY------------FLQLKFDPELL----FGVQFQYR-----NRIAME  379
               I   +    GY             L  +F   +L    F +  QYR     + + + 
Sbjct  442  RARIRRTLGPYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLS  501

Query  380  FNHLYHWHPLMPDSFK--VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR  437
                  W  +        +   + +  +     SMLVD     L D   +Q+  RIG   
Sbjct  502  SVFFASWRIIHEGGIDPILRGLKATPAKLYRQDSMLVD----ELRDKLFQQVR-RIG---  553

Query  438  NMDHHILHVAVDVIRESREMRLQPFNEYRKRFGM---KPYTSFQELVGEKEMAAELEELY  494
                  L +A   ++ SR+  L  +N +R+  G+   +       ++  +++A +   LY
Sbjct  554  ------LDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLRLY  607

Query  495  GDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVG  554
               D ++ + G + E   P +  G  +  +      +   G+      +W+      +  
Sbjct  608  KTPDNIDIWVGAIAEPLLPGARVGPLLACLFENQFRRARDGDRF----WWQKWGVFTKRQ  663

Query  555  FNIVKTATLKKLVCLNT  571
               ++  +L ++VC NT
Sbjct  664  RKALRRISLSRIVCDNT  680


>sp|Q9QW30.1|NOTC2_RAT  RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 
2; Contains: RecName: Full=Notch 2 extracellular truncation; 
Contains: RecName: Full=Notch 2 intracellular domain; 
Flags: Precursor
Length=2471

 GENE ID: 29492 Notch2 | Notch homolog 2 (Drosophila) [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 38.5 bits (88),  Expect = 0.12, Method: Composition-based stats.
 Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 8/54 (14%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSP  85
             +N C   PC + G CV  GL  Y+C C   GY+G NC        L N   PSP
Sbjct  1026  INECSSNPCLNSGTCVD-GLGTYRCTCP-LGYTGKNCQT------LVNLCSPSP  1071


 Score = 34.3 bits (77),  Expect = 1.9, Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
             ++ C   PCQH   C  F +  Y+C+C   GY G NC
Sbjct  1150  LDECASNPCQHGATCSDF-IGGYRCECV-PGYQGVNC  1184


 Score = 34.3 bits (77),  Expect = 2.0, Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            VN C   PC + G CV   ++R+QC C   G++GP C I
Sbjct  495  VNECQSNPCVNNGQCVD-KVNRFQCLCP-PGFTGPVCQI  531


 Score = 33.5 bits (75),  Expect = 3.7, Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 6/44 (13%)

Query  33   NPC-CYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWT  75
            +PC    PCQ+ G C     D Y+C C + G++G  C     WT
Sbjct  107  HPCFVSRPCQNGGTCHMLSWDTYECTC-QVGFTGKQCQ----WT  145


 Score = 32.3 bits (72),  Expect = 7.6, Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 2/32 (6%)

Query  39   PCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            PC+H G CV      + C+C + GY+GP C +
Sbjct  426  PCEHAGKCVNTD-GAFHCECLK-GYAGPRCEM  455


 Score = 32.3 bits (72),  Expect = 8.0, Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            N C   PCQ+ G C    ++ Y+C C + G+ G NC +
Sbjct  759  NECLSNPCQNGGTCNNL-VNGYRCTC-KKGFKGYNCQV  794


>sp|P78504.3|JAG1_HUMAN  RecName: Full=Protein jagged-1; Short=Jagged1; Short=hJ1; AltName: 
CD_antigen=CD339; Flags: Precursor
Length=1218

 GENE ID: 182 JAG1 | jagged 1 (Alagille syndrome) [Homo sapiens]
(Over 10 PubMed links)

 Score = 38.1 bits (87),  Expect = 0.16, Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query  37   YYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            + PC + G C   G D+YQC C   GYSGPNC I
Sbjct  303  HQPCLNGGTCSNTGPDKYQCSCPE-GYSGPNCEI  335


>sp|P82279.2|CRUM1_HUMAN  RecName: Full=Crumbs homolog 1; Flags: Precursor
Length=1406

 GENE ID: 23418 CRB1 | crumbs homolog 1 (Drosophila) [Homo sapiens]
(Over 10 PubMed links)

 Score = 37.7 bits (86),  Expect = 0.18, Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 3/46 (6%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT--IPGLWT  75
             + C   PC H G+CV  G +RY C+CT +G++G +C   +P  W+
Sbjct  263  TDECASQPCLHGGLCVD-GENRYSCNCTGSGFTGTHCETLMPLCWS  307


>sp|P34576.2|MUA3_CAEEL  RecName: Full=Transmembrane cell adhesion receptor mua-3; AltName: 
Full=Muscle attachment abnormal protein 3; Flags: Precursor
Length=3767

 GENE ID: 176430 mua-3 | MUscle Attachment abnormal [Caenorhabditis elegans]
(10 or fewer PubMed links)

 Score = 37.7 bits (86),  Expect = 0.21, Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 1/48 (2%)

Query  25    DPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG  72
             +P  P P NPC    C   G C+      Y+C+C   GY   N   PG
Sbjct  3170  NPTQPDPFNPCFKNDCDPHGKCIEISKYAYKCECG-VGYRDINPQSPG  3216


>sp|Q6DCQ6.1|VWA2_XENLA  RecName: Full=von Willebrand factor A domain-containing protein 
2; AltName: Full=A domain-containing protein similar to matrilin 
and collagen; Short=AMACO; Flags: Precursor
Length=790

 GENE ID: 446887 MGC80919 | MGC80919 protein [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 37.4 bits (85),  Expect = 0.23, Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 26/42 (61%), Gaps = 5/42 (11%)

Query  28   APTPVNPCCYYPCQHQGICV-RFGLDRYQCDCTRTGYSGPNC  68
            A +PVN C   PC + G+C+ R G   Y+CDC   G+ GP+C
Sbjct  710  AKSPVNLCKPNPCMNDGVCILRQG--SYRCDC--RGWDGPHC  747


 Score = 33.9 bits (76),  Expect = 2.7, Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 8/97 (8%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSL------RPSPS  86
            +PC   PC++ G C+  G D+Y C C   G+ G     P L       L        + S
Sbjct  296  DPCDSQPCKNGGTCIAEGQDKYHCVCP-AGFGGDTECAPQLSLECNIDLLFLVDSSDTTS  354

Query  87   FTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLI  123
               F + H  +   F+ A+   E  + + +   SN +
Sbjct  355  LEAF-MQHKSFLKRFIQASLSDESPLNVGVAQYSNEV  390


>sp|P55067.1|NCAN_RAT  RecName: Full=Neurocan core protein; AltName: Full=Chondroitin 
sulfate proteoglycan 3; AltName: Full=245 kDa early postnatal 
core glycoprotein; Contains: RecName: Full=150 kDa adult 
core glycoprotein; Flags: Precursor
Length=1257

 GENE ID: 58982 Ncan | neurocan [Rattus norvegicus] (Over 10 PubMed links)

 Score = 37.4 bits (85),  Expect = 0.23, Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 2/44 (4%)

Query  27   GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            G   P +PC   PC H G C   G   Y C C + GY+G NC I
Sbjct  945  GQEDPTDPCENNPCLHGGTCRTNGT-MYGCSCDQ-GYAGENCEI  986


>sp|P49013.1|FBP3_STRPU  RecName: Full=Fibropellin-3; AltName: Full=Fibropellin III; AltName: 
Full=Fibropellin-c; AltName: Full=Epidermal growth factor-related 
protein 3; AltName: Full=SpEGF III; Flags: Precursor
Length=570

 GENE ID: 373315 EGFIII | fibropellin c [Strongylocentrotus purpuratus]
(10 or fewer PubMed links)

 Score = 37.4 bits (85),  Expect = 0.27, Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 2/39 (5%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            T +N C   PCQ+ G C    ++RY CDC R G++G NC
Sbjct  289  TDINECASSPCQNGGSCTD-AVNRYTCDC-RAGFTGSNC  325


 Score = 32.3 bits (72),  Expect = 8.1, Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 8/49 (16%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPN------CTIPGLW  74
            +N C   PCQ+ G C+  G+  Y C C R GY+G N      C + G+W
Sbjct  405  INECASLPCQNGGECIN-GIAMYICQC-RQGYAGVNCEEVGFCDLEGVW  451


>sp|Q5GFL6.1|VWA2_HUMAN  RecName: Full=von Willebrand factor A domain-containing protein 
2; AltName: Full=A domain-containing protein similar to matrilin 
and collagen; Short=AMACO; AltName: Full=Colon cancer 
secreted protein 2; Short=CCSP-2; Flags: Precursor
Length=755

 GENE ID: 340706 VWA2 | von Willebrand factor A domain containing 2
[Homo sapiens] (10 or fewer PubMed links)

 Score = 37.0 bits (84),  Expect = 0.30, Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 0/38 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
             PC   PCQ+ G CV  GLD YQC C        NC +
Sbjct  297  GPCDSQPCQNGGTCVPEGLDGYQCLCPLAFGGEANCAL  334


 Score = 35.4 bits (80),  Expect = 1.1, Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query  28   APTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            A  PVN C   PC ++G CV      Y+C C R G+ GP+C
Sbjct  709  AKQPVNLCKPSPCMNEGSCV-LQNGSYRCKC-RDGWEGPHC  747


>sp|Q13201.3|MMRN1_HUMAN  RecName: Full=Multimerin-1; AltName: Full=Endothelial cell multimerin; 
AltName: Full=EMILIN-4; AltName: Full=Elastin microfibril 
interface located protein 4; Short=Elastin microfibril 
interfacer 4; Flags: Precursor
Length=1228

 GENE ID: 22915 MMRN1 | multimerin 1 [Homo sapiens] (Over 10 PubMed links)

 Score = 37.0 bits (84),  Expect = 0.30, Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 2/42 (4%)

Query  29    PTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
             P   + C  +PCQ+ G C+  G   + C C R  ++G NCTI
Sbjct  1039  PEEYSSCSRHPCQNGGTCIN-GRTSFTCAC-RHPFTGDNCTI  1078


>sp|P55066.1|NCAN_MOUSE  RecName: Full=Neurocan core protein; AltName: Full=Chondroitin 
sulfate proteoglycan 3; Flags: Precursor
Length=1268

 GENE ID: 13004 Ncan | neurocan [Mus musculus] (Over 10 PubMed links)

 Score = 37.0 bits (84),  Expect = 0.37, Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 2/44 (4%)

Query  27   GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            G   P +PC   PC H G C   G   Y C C + GY+G NC I
Sbjct  956  GQEDPTDPCENNPCLHGGTCHTNGT-VYGCSCDQ-GYAGENCEI  997


>sp|O88279.1|SLIT1_RAT  RecName: Full=Slit homolog 1 protein; Short=Slit-1; AltName: 
Full=Multiple epidermal growth factor-like domains 4; Flags: 
Precursor
Length=1531

 GENE ID: 65047 Slit1 | slit homolog 1 (Drosophila) [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 36.6 bits (83),  Expect = 0.40, Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
             +PC   PCQ+QG C    L+ Y+C C  +GY G NC +
Sbjct  926  CDPCLSSPCQNQGTCHNDPLEVYRCTCP-SGYKGRNCEV  963


>sp|Q94887.2|NRX4_DROME  RecName: Full=Neurexin-4; AltName: Full=Neurexin IV; Flags: Precursor
Length=1284

 Score = 36.6 bits (83),  Expect = 0.46, Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            ++ C   PCQH+G+C +   + + CDC  TGY+G  C
Sbjct  543  IDRCNPNPCQHKGLCHQNSREFF-CDCGHTGYAGAVC  578


 Score = 32.3 bits (72),  Expect = 9.0, Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 1/38 (2%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT  69
            V  C   PC + G C+    D Y CDC  + + GP C 
Sbjct  963  VGRCESNPCLNNGTCIE-RYDGYSCDCRWSAFKGPICA  999


>sp|P21783.3|NOTCH_XENLA  RecName: Full=Neurogenic locus notch protein homolog; Short=xOTCH; 
Flags: Precursor
Length=2524

 GENE ID: 394367 notch1-a | Notch protein [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 36.2 bits (82),  Expect = 0.54, Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
             +N C  +PCQ+ G C+   ++ Y+C C R G  G +C I
Sbjct  1183  INECLSHPCQNGGTCIDL-INTYKCSCPR-GTQGVHCEI  1219


 Score = 34.7 bits (78),  Expect = 1.4, Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            T ++ C   PC H G C+   ++ ++CDC  TG+SG  C
Sbjct  488  TNIDECASNPCLHNGKCID-KINEFRCDCP-TGFSGNLC  524


 Score = 32.3 bits (72),  Expect = 8.1, Method: Composition-based stats.
 Identities = 15/38 (39%), Positives = 18/38 (47%), Gaps = 1/38 (2%)

Query  31   PVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            P  PC   PC + G C +     Y C C   G+SG NC
Sbjct  217  PYVPCNPSPCLNGGTCRQTDDTSYDCTCL-PGFSGQNC  253


>sp|Q70UZ7.1|VWA2_MOUSE  RecName: Full=von Willebrand factor A domain-containing protein 
2; AltName: Full=A domain-containing protein similar to matrilin 
and collagen; Short=AMACO; Flags: Precursor
Length=791

 GENE ID: 240675 Vwa2 | von Willebrand factor A domain containing 2
[Mus musculus] (10 or fewer PubMed links)

 Score = 36.2 bits (82),  Expect = 0.56, Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 2/41 (4%)

Query  28   APTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            A  PVN C   PC ++G CV      Y+C+C R G+ GP+C
Sbjct  708  ARLPVNLCKPSPCMNEGTCV-LKNGSYRCEC-RGGWEGPHC  746


 Score = 35.8 bits (81),  Expect = 0.79, Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 16/26 (61%), Gaps = 0/26 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDC  58
             PC   PCQ+ G C+  G+DRY C C
Sbjct  296  GPCDSQPCQNGGTCIPEGVDRYHCLC  321


>sp|P97846.1|CNTP1_RAT  RecName: Full=Contactin-associated protein 1; Short=Caspr1; Short=Caspr; 
AltName: Full=Neurexin 4; AltName: Full=Neurexin 
IV; AltName: Full=p190; AltName: Full=Paranodin; Flags: Precursor
Length=1381

 GENE ID: 84008 Cntnap1 | contactin associated protein 1 [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 36.2 bits (82),  Expect = 0.62, Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 11/64 (17%)

Query  38    YPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT--IPGLW---TWLRNSLR-----PSPSF  87
             +PC H G CV      Y CDC  T + GP C   I G +   TW+R +L+      +  F
Sbjct  967   FPCFHGGRCVE-RYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAQEF  1025

Query  88    THFL  91
             +H L
Sbjct  1026  SHML  1029


>sp|O54991.1|CNTP1_MOUSE  RecName: Full=Contactin-associated protein 1; Short=Caspr1; Short=Caspr; 
AltName: Full=Neurexin 4; AltName: Full=Neurexin 
IV; AltName: Full=Paranodin; AltName: Full=NCP1; AltName: Full=MHDNIV; 
Flags: Precursor
Length=1385

 GENE ID: 53321 Cntnap1 | contactin associated protein-like 1 [Mus musculus]
(Over 10 PubMed links)

 Score = 35.8 bits (81),  Expect = 0.66, Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 11/64 (17%)

Query  38    YPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT--IPGLW---TWLRNSLR-----PSPSF  87
             +PC H G CV      Y CDC  T + GP C   I G +   TW+R +L+      +  F
Sbjct  967   FPCFHGGRCVE-RYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAREF  1025

Query  88    THFL  91
             +H L
Sbjct  1026  SHML  1029


>sp|O35516.1|NOTC2_MOUSE  RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 
2; AltName: Full=Motch B; Contains: RecName: Full=Notch 
2 extracellular truncation; Contains: RecName: Full=Notch 
2 intracellular domain; Flags: Precursor
Length=2470

 GENE ID: 18129 Notch2 | Notch gene homolog 2 (Drosophila) [Mus musculus]
(Over 100 PubMed links)

 Score = 35.8 bits (81),  Expect = 0.72, Method: Composition-based stats.
 Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 2/37 (5%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
             +N C   PC + G CV  GL  Y+C C   GY+G NC
Sbjct  1024  INECSSNPCLNAGTCVD-GLGTYRCICP-LGYTGKNC  1058


 Score = 34.7 bits (78),  Expect = 1.8, Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            VN C   PC + G CV   ++R+QC C   G++GP C I
Sbjct  493  VNECQSNPCVNNGQCVD-KVNRFQCLCP-PGFTGPVCQI  529


 Score = 33.9 bits (76),  Expect = 2.6, Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query  32    VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
             ++ C   PCQH   C  F +  Y+C+C   GY G NC
Sbjct  1148  LDECASNPCQHGATCNDF-IGGYRCECV-PGYQGVNC  1182


 Score = 33.5 bits (75),  Expect = 4.1, Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 6/44 (13%)

Query  33   NPC-CYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWT  75
            +PC    PCQ+ G C     D Y+C C + G++G  C     WT
Sbjct  107  HPCFVSRPCQNGGTCHMLSRDTYECTC-QVGFTGKQCQ----WT  145


 Score = 32.3 bits (72),  Expect = 7.3, Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 2/32 (6%)

Query  39   PCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            PC+H G CV      + C+C + GY+GP C +
Sbjct  424  PCEHAGKCVNTD-GAFHCECLK-GYAGPRCEM  453


 Score = 32.3 bits (72),  Expect = 7.5, Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            N C   PCQ+ G C    ++ Y+C C + G+ G NC +
Sbjct  757  NECLSNPCQNGGTCNNL-VNGYRCTC-KKGFKGYNCQV  792


>sp|A8G3U9.1|DCUP_PROM2  Uroporphyrinogen decarboxylase (URO-D) (UPD)
Length=346

 Score = 35.4 bits (80),  Expect = 0.95, Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 11/85 (12%)

Query  308  HNRVCDLLKAEHP----------TWGDEQLFQTTRLILIGETIKIVIEEYVQQL-SGYFL  356
              +V D++KAEHP          + G  +    T + +I     + IEE  +++ SG  +
Sbjct  226  QKKVVDIVKAEHPETPVILYISGSAGVIERMAKTGIDIISLDWTVDIEEACKRIPSGIGI  285

Query  357  QLKFDPELLFGVQFQYRNRIAMEFN  381
            Q   DP +LFG +   + RI   FN
Sbjct  286  QGNVDPGILFGNKESIKERIDNTFN  310


>sp|P47612.1|THII_MYCGE  RecName: Full=Probable thiamine biosynthesis protein thiI
Length=385

 Score = 35.4 bits (80),  Expect = 1.0, Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 25/38 (65%), Gaps = 2/38 (5%)

Query  280  PQSQMAVGQEVFGLLPGLML--YATLWLREHNRVCDLL  315
             + Q A+ QE+F  LPG+ L  +A+  +RE N++ DLL
Sbjct  60   KKEQRAILQELFSFLPGISLFFFASQIVREENKLLDLL  97


>sp|O88278.1|CELR3_RAT  RecName: Full=Cadherin EGF LAG seven-pass G-type receptor 3; 
AltName: Full=Multiple epidermal growth factor-like domains 
2; Flags: Precursor
Length=3313

 GENE ID: 83466 Celsr3 | cadherin, EGF LAG seven-pass G-type receptor 3
(flamingo homolog, Drosophila) [Rattus norvegicus] (10 or fewer PubMed links)

 Score = 35.0 bits (79),  Expect = 1.1, Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 3/43 (6%)

Query  28    APTPVNPCCYYPCQHQGIC--VRFGLDRYQCDCTRTGYSGPNC  68
              P  V+ C   PCQ+QG C  ++ G   Y CDC  +GY G +C
Sbjct  1969  GPGCVDACLLNPCQNQGSCRHLQGGPHGYTCDCA-SGYFGQHC  2010


>sp|O60494.3|CUBN_HUMAN  RecName: Full=Cubilin; AltName: Full=Intrinsic factor-cobalamin 
receptor; AltName: Full=Intrinsic factor-vitamin B12 receptor; 
AltName: Full=460 kDa receptor; AltName: Full=Intestinal 
intrinsic factor receptor; Flags: Precursor
Length=3623

 GENE ID: 8029 CUBN | cubilin (intrinsic factor-cobalamin receptor)
[Homo sapiens] (Over 10 PubMed links)

 Score = 35.0 bits (79),  Expect = 1.2, Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP  71
            +N C   PC + G CV  G+D + C+CTR  ++G  C +P
Sbjct  433  INECLSNPCLNGGTCVD-GVDSFSCECTRL-WTGALCQVP  470


>sp|P78357.1|CNTP1_HUMAN  RecName: Full=Contactin-associated protein 1; Short=Caspr1; Short=Caspr; 
AltName: Full=Neurexin 4; AltName: Full=Neurexin 
IV; AltName: Full=p190; Flags: Precursor
Length=1384

 GENE ID: 8506 CNTNAP1 | contactin associated protein 1 [Homo sapiens]
(10 or fewer PubMed links)

 Score = 34.7 bits (78),  Expect = 1.5, Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 11/63 (17%)

Query  39    PCQHQGICVRFGLDRYQCDCTRTGYSGPNCT--IPGLW---TWLRNSLR-----PSPSFT  88
             PC H G CV      Y CDC  T + GP C   I G +   TW+R +L+      +  F+
Sbjct  967   PCFHGGRCVE-RYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFS  1025

Query  89    HFL  91
             H L
Sbjct  1026  HML  1028


>sp|Q01705.2|NOTC1_MOUSE  RecName: Full=Neurogenic locus notch homolog protein 1; Short=Notch 
1; AltName: Full=Motch A; Short=mT14; AltName: Full=p300; 
Contains: RecName: Full=Notch 1 extracellular truncation; 
Contains: RecName: Full=Notch 1 intracellular domain; Flags: 
Precursor
Length=2531

 GENE ID: 18128 Notch1 | Notch gene homolog 1 (Drosophila) [Mus musculus]
(Over 100 PubMed links)

 Score = 34.7 bits (78),  Expect = 1.5, Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 27/46 (58%), Gaps = 3/46 (6%)

Query  25   DPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            DP   + VN C   PC H G C R GL+ Y+CDC   G+SG NC I
Sbjct  710  DPTCLSEVNECNSNPCIH-GAC-RDGLNGYKCDCA-PGWSGTNCDI  752


>sp|Q07008.2|NOTC1_RAT  RecName: Full=Neurogenic locus notch homolog protein 1; Short=Notch 
1; Contains: RecName: Full=Notch 1 extracellular truncation; 
Contains: RecName: Full=Notch 1 intracellular domain; 
Flags: Precursor
Length=2531

 GENE ID: 25496 Notch1 | Notch homolog 1, translocation-associated (Drosophila)
[Rattus norvegicus] (Over 10 PubMed links)

 Score = 34.7 bits (78),  Expect = 1.6, Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 27/46 (58%), Gaps = 3/46 (6%)

Query  25   DPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
            DP   + VN C   PC H G C R GL+ Y+CDC   G+SG NC I
Sbjct  710  DPTCLSEVNECNSNPCIH-GAC-RDGLNGYKCDCA-PGWSGTNCDI  752


>sp|Q80TR4.2|SLIT1_MOUSE  RecName: Full=Slit homolog 1 protein; Short=Slit-1; Flags: Precursor
Length=1531

 GENE ID: 20562 Slit1 | slit homolog 1 (Drosophila) [Mus musculus]
(Over 10 PubMed links)

 Score = 34.7 bits (78),  Expect = 1.8, Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
             +PC   PCQ+QG C    L+ Y+C C  +GY G +C +
Sbjct  926  CDPCLSSPCQNQGTCHNDPLEVYRCTCP-SGYKGRHCEV  963


>sp|Q9CPW0.2|CNTP2_MOUSE  RecName: Full=Contactin-associated protein-like 2; AltName: Full=Cell 
recognition molecule Caspr2; Flags: Precursor
Length=1332

 GENE ID: 66797 Cntnap2 | contactin associated protein-like 2 [Mus musculus]
(Over 10 PubMed links)

 Score = 34.3 bits (77),  Expect = 2.1, Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            ++ C    C+H G C +   D ++C C  TGYSG  C
Sbjct  555  IDRCVPNHCEHGGKCSQ-TWDSFKCTCDETGYSGATC  590


>sp|Q9VW71.2|FAT2_DROME  RecName: Full=Putative fat-like cadherin-related tumor suppressor 
homolog; Flags: Precursor
Length=4705

 Score = 34.3 bits (77),  Expect = 2.1, Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query  35    CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI  70
             C   PC + GIC     D ++C C +  YSG +C I
Sbjct  4133  CGSQPCANSGICKELDTDVFECAC-QPRYSGKHCEI  4167


>sp|Q9IAT6.1|DLLC_DANRE  RecName: Full=Delta-like protein C; Short=DeltaC; Short=delC; 
Flags: Precursor
Length=664

 GENE ID: 30120 dlc | deltaC [Danio rerio] (Over 10 PubMed links)

 Score = 34.3 bits (77),  Expect = 2.1, Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 2/61 (3%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTH  89
            T ++ C   PCQ+ G CV  G++ Y C CT  G+SG +C +                +TH
Sbjct  419  TNIDDCSSNPCQNAGTCVD-GINGYTCTCT-LGFSGKDCRVRSDACSFMPCQNGGTCYTH  476

Query  90   F  90
            F
Sbjct  477  F  477


>sp|Q9WVB4.1|SLIT3_MOUSE  RecName: Full=Slit homolog 3 protein; Short=Slit-3; Short=Slit3; 
Flags: Precursor
Length=1523

 GENE ID: 20564 Slit3 | slit homolog 3 (Drosophila) [Mus musculus]
(Over 10 PubMed links)

 Score = 34.3 bits (77),  Expect = 2.2, Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 29/48 (60%), Gaps = 2/48 (4%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRN  79
             N C   PC++ G C +  +++Y+C C  + Y G +CT+P + T ++N
Sbjct  917  CNACLSSPCKNNGTCSQDPVEQYRCTCPYS-YKGKDCTVP-INTCVQN  962


>sp|Q9UHC6.1|CNTP2_HUMAN  RecName: Full=Contactin-associated protein-like 2; AltName: Full=Cell 
recognition molecule Caspr2; Flags: Precursor
Length=1331

 GENE ID: 26047 CNTNAP2 | contactin associated protein-like 2 [Homo sapiens]
(Over 10 PubMed links)

 Score = 34.3 bits (77),  Expect = 2.4, Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            ++ C    C+H G C +   D ++C C  TGYSG  C
Sbjct  555  IDRCVPNHCEHGGKCSQ-TWDSFKCTCDETGYSGATC  590


>sp|O88280.1|SLIT3_RAT  RecName: Full=Slit homolog 3 protein; Short=Slit-3; AltName: 
Full=Multiple epidermal growth factor-like domains 5; Flags: 
Precursor
Length=1523

 GENE ID: 83467 Slit3 | slit homolog 3 (Drosophila) [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 33.9 bits (76),  Expect = 2.4, Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 29/48 (60%), Gaps = 2/48 (4%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRN  79
             N C   PC++ G C +  +++Y+C C  + Y G +CT+P + T ++N
Sbjct  917  CNACLSSPCKNNGTCSQDPVEQYRCTCPYS-YKGKDCTVP-INTCVQN  962


>sp|Q9R1B9.1|SLIT2_MOUSE  RecName: Full=Slit homolog 2 protein; Short=Slit-2; Contains: 
RecName: Full=Slit homolog 2 protein N-product; Contains: RecName: 
Full=Slit homolog 2 protein C-product; Flags: Precursor
Length=1521

 GENE ID: 20563 Slit2 | slit homolog 2 (Drosophila) [Mus musculus]
(Over 10 PubMed links)

 Score = 33.9 bits (76),  Expect = 2.6, Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP  71
             NPC   PC++ G C    +D Y+C C   G+ G +C +P
Sbjct  911  CNPCLSNPCKNDGTCNNDPVDFYRCTCP-YGFKGQDCDVP  949


>sp|A0A1F4.1|EYS_DROME  RecName: Full=Protein eyes shut; AltName: Full=Protein spacemaker
Length=2176

 Score = 33.9 bits (76),  Expect = 3.0, Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 2/37 (5%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            +N C   PCQ+ G+CV   L  Y C C   GY+G NC
Sbjct  301  INECASSPCQNGGVCVD-KLAAYACACP-MGYTGINC  335


>sp|Q90Y54.1|JAG1B_DANRE  RecName: Full=Protein jagged-1b; Short=Jagged1b; AltName: Full=Jagged3; 
Flags: Precursor
Length=1213

 GENE ID: 140423 jag1b | jagged 1b [Danio rerio] (Over 10 PubMed links)

 Score = 33.9 bits (76),  Expect = 3.0, Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 19/32 (59%), Gaps = 1/32 (3%)

Query  37   YYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC  68
            + PC + G C   G D+YQC C   GYSG NC
Sbjct  300  HQPCLNGGTCSNTGPDKYQCSC-EDGYSGVNC  330
Select All Get selected sequences
sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase...

Distribution of 150 Blast Hits on the Query Sequence [?]
