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Alignment Text XML ASN.1 Hit Table(text) Hit Table(csv)	Search Strategies ASN.1	Bioseq ASN.1	PSSM Text	PssmWithParameters ASN.1	[?]
sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase...

Query ID: lcl|9149
Description: sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase 1 OS=Homo sapiens GN=PTGS1 PE=1 SV=1
Molecule type: amino acid
Query Length: 599
Database Name: swissprot
Description: Non-redundant SwissProt sequences See details
Program: BLASTP 2.2.19+ Citation
Other reports: Search Summary [Distance tree of results]
Search Parameters
Program	blastp
Word size	3
Expect value	10
Hitlist size	100
Gapcosts	11,1
Matrix	BLOSUM62
Threshold	11
Composition-based stats	2
Low Complexity Filter	Yes
Filter string	L;
Genetic Code	1
Window Size	40
Database
Posted date	Feb 8, 2009 5:55 PM
Number of letters	134,540,208
Number of sequences	358,519
Entrez query	none
Karlin-Altschul statistics
Params	Ungapped	Gapped
Lambda	0.321898	0.267
K	0.140185	0.041
H	0.44714	0.14
Results Statistics
Length adjustment	121
Effective length of query	478
Effective length of database	91159409
Effective search space	43574197502
Effective search space used	43574197502
Alignments Select All Get selected sequences

>sp|P23219.1|PGH1_HUMAN  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=599

 GENE ID: 5742 PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxygenase) [Homo sapiens] (Over 100 PubMed links)

 Score = 1141 bits (2952),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 576/576 (100%), Positives = 576/576 (100%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP
Sbjct  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN
Sbjct  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQH
Sbjct  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQH  203

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP
Sbjct  204  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG
Sbjct  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL
Sbjct  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI
Sbjct  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY
Sbjct  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL
Sbjct  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
Sbjct  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599


>sp|P05979.2|PGH1_SHEEP  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=600

 GENE ID: 443551 PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin
G/H synthase and cyclooxygenase) [Ovis aries] (Over 10 PubMed links)

 Score = 1072 bits (2771),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 534/576 (92%), Positives = 554/576 (96%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPGAP PVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP +WTWLR +LRP
Sbjct  25   ADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPEIWTWLRTTLRP  84

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSF HF+LTHGRW W+FVNATFIR+ LMRLVLTVRSNLIPSPPTYN AHDYISWESFSN
Sbjct  85   SPSFIHFMLTHGRWLWDFVNATFIRDTLMRLVLTVRSNLIPSPPTYNIAHDYISWESFSN  144

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVP+DCPTPMGTKGKKQLPDA+ L+RRFLLRRKFIPDPQGTNLMFAFFAQH
Sbjct  145  VSYYTRILPSVPRDCPTPMGTKGKKQLPDAEFLSRRFLLRRKFIPDPQGTNLMFAFFAQH  204

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQ+L+GE+YPP
Sbjct  205  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPP  264

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT+WLREHNRVCDLLKAEHPTWG
Sbjct  265  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATIWLREHNRVCDLLKAEHPTWG  324

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQT RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFG QFQYRNRIAMEFN L
Sbjct  325  DEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQL  384

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF+VG Q+YSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN+DHHI
Sbjct  385  YHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHI  444

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAVDVI+ESR +RLQPFNEYRKRFGMKPYTSFQEL GEKEMAAELEELYGDIDALEFY
Sbjct  445  LHVAVDVIKESRVLRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFY  504

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKCHPNSIFGESMIE+GAPFSLKGLLGNPICSPEYWK STFGGEVGFN+VKTATL
Sbjct  505  PGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGEVGFNLVKTATL  564

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSF VPD  Q+D P VERP TEL
Sbjct  565  KKLVCLNTKTCPYVSFHVPDPRQEDRPGVERPPTEL  600


>sp|O62664.2|PGH1_BOVIN  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=600

 GENE ID: 282022 PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin
G/H synthase and cyclooxygenase) [Bos taurus] (10 or fewer PubMed links)

 Score = 1068 bits (2762),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 532/576 (92%), Positives = 554/576 (96%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPGAP PVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGY GPNCTIP +WTWLR +LRP
Sbjct  25   ADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYYGPNCTIPEIWTWLRTTLRP  84

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSF HFLLTHGRW W+FVNATFIR+ LMRLVLTVRSNLIPSPPTYN AHDYISWESFSN
Sbjct  85   SPSFVHFLLTHGRWLWDFVNATFIRDKLMRLVLTVRSNLIPSPPTYNVAHDYISWESFSN  144

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVP+DCPTPMGTKGKKQLPDA+ L+RRFLLRRKFIPDPQGTNLMFAFFAQH
Sbjct  145  VSYYTRILPSVPRDCPTPMGTKGKKQLPDAEFLSRRFLLRRKFIPDPQGTNLMFAFFAQH  204

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQ+L+GE+YPP
Sbjct  205  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPP  264

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLM+YAT+WLREHNRVCDLLKAEHPTWG
Sbjct  265  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMVYATIWLREHNRVCDLLKAEHPTWG  324

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQT RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFG QFQYRNRIAMEFN L
Sbjct  325  DEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQL  384

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF+VG Q+YSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN+DHHI
Sbjct  385  YHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHI  444

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAVDVI+ESRE+RLQPFNEYRKRFGMKPYTSFQEL GEKEMAAELEELYGDIDALEFY
Sbjct  445  LHVAVDVIKESRELRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFY  504

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKCHPNSIFGESMIE+GAPFSLKGLLGNPICSPEYWK STFGG+VGFN+VKTATL
Sbjct  505  PGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGDVGFNLVKTATL  564

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSF VPD  ++D P VERP TEL
Sbjct  565  KKLVCLNTKTCPYVSFHVPDPHREDRPGVERPPTEL  600


>sp|O97554.1|PGH1_RABIT  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=606

 GENE ID: 100009407 COX-1 | cyclooxygenase-1 [Oryctolagus cuniculus]

 Score = 1063 bits (2748),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 527/576 (91%), Positives = 552/576 (95%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPGAP PVNPCCY+PCQHQG+CVR  LDRYQCDCTRTGYSGPNCT+P LWTWLR+SLRP
Sbjct  31   ADPGAPAPVNPCCYFPCQHQGVCVRVALDRYQCDCTRTGYSGPNCTVPDLWTWLRSSLRP  90

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SP+F H+LLTH RWFWEFVNATFIR+ LMRLVLTVRSNLIPSPPTYN  +DYISWE+FSN
Sbjct  91   SPTFVHYLLTHVRWFWEFVNATFIRDTLMRLVLTVRSNLIPSPPTYNLDYDYISWEAFSN  150

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTR+LPSVPKDCPTPMGTKGKKQLPDAQ+LA RFLLRR FIPDPQGTNLMFAFFAQH
Sbjct  151  VSYYTRVLPSVPKDCPTPMGTKGKKQLPDAQVLAHRFLLRRTFIPDPQGTNLMFAFFAQH  210

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGD+LERQY LRLFKDGKLKYQVLDGE+YPP
Sbjct  211  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDSLERQYHLRLFKDGKLKYQVLDGEVYPP  270

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVEEAPVLMHYPRG+PP+SQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTW 
Sbjct  271  SVEEAPVLMHYPRGVPPRSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWD  330

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPE+LF VQFQYRNRIAMEFNHL
Sbjct  331  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPEMLFSVQFQYRNRIAMEFNHL  390

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF+VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN+DHH+
Sbjct  391  YHWHPLMPDSFQVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQSAGRIGGGRNIDHHV  450

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAV+VI+ESREMRLQPFNEYRKRFG+KPY SFQEL GE EMAAELEELYGDIDALEFY
Sbjct  451  LHVAVEVIKESREMRLQPFNEYRKRFGLKPYASFQELTGETEMAAELEELYGDIDALEFY  510

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKC PNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVG N++KTATL
Sbjct  511  PGLLLEKCQPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGSNLIKTATL  570

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSFRVP +S DDGPA ER STEL
Sbjct  571  KKLVCLNTKTCPYVSFRVPRSSGDDGPAAERRSTEL  606


>sp|P22437.1|PGH1_MOUSE  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=602

 GENE ID: 19224 Ptgs1 | prostaglandin-endoperoxide synthase 1 [Mus musculus]
(Over 100 PubMed links)

 Score = 1038 bits (2684),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 518/576 (89%), Positives = 546/576 (94%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            ADPG P+PVNPCCYYPCQ+QG+CVRFGLD YQCDCTRTGYSGPNCTIP +WTWLRNSLRP
Sbjct  27   ADPGVPSPVNPCCYYPCQNQGVCVRFGLDNYQCDCTRTGYSGPNCTIPEIWTWLRNSLRP  86

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSFTHFLLTHG W WEFVNATFIRE+LMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN
Sbjct  87   SPSFTHFLLTHGYWLWEFVNATFIREVLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  146

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVPKDCPTPMGTKGKKQLPD QLLA++ LLRR+FIP PQGTN++FAFFAQH
Sbjct  147  VSYYTRILPSVPKDCPTPMGTKGKKQLPDVQLLAQQLLLRREFIPAPQGTNILFAFFAQH  206

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQY LRLFKDGKLKYQVLDGE+YPP
Sbjct  207  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYHLRLFKDGKLKYQVLDGEVYPP  266

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVE+A VLM YP G+PP+ QMAVGQEVFGLLPGLML++T+WLREHNRVCDLLK EHPTW 
Sbjct  267  SVEQASVLMRYPPGVPPERQMAVGQEVFGLLPGLMLFSTIWLREHNRVCDLLKEEHPTWD  326

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLILIGETIKIVIEEYVQ LSGYFLQLKFDPELLF  QFQYRNRIAMEFNHL
Sbjct  327  DEQLFQTTRLILIGETIKIVIEEYVQHLSGYFLQLKFDPELLFRAQFQYRNRIAMEFNHL  386

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMP+SF+VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN D+H+
Sbjct  387  YHWHPLMPNSFQVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQRAGRIGGGRNFDYHV  446

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVAVDVI+ESREMRLQPFNEYRKRFG+KPYTSFQEL GEKEMAAELEELYGDIDALEFY
Sbjct  447  LHVAVDVIKESREMRLQPFNEYRKRFGLKPYTSFQELTGEKEMAAELEELYGDIDALEFY  506

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEKC PNSIFGESMIE+GAPFSLKGLLGNPICSPEYWKPSTFGG+VGFN+V TA+L
Sbjct  507  PGLLLEKCQPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKPSTFGGDVGFNLVNTASL  566

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSFRVPD   DDG  + R STEL
Sbjct  567  KKLVCLNTKTCPYVSFRVPDYPGDDGSVLVRRSTEL  602


>sp|Q63921.2|PGH1_RAT  RecName: Full=Prostaglandin G/H synthase 1; AltName: Full=Cyclooxygenase-1; 
Short=COX-1; AltName: Full=Prostaglandin-endoperoxide 
synthase 1; AltName: Full=Prostaglandin H2 synthase 
1; Short=PGH synthase 1; Short=PGHS-1; Short=PHS 1; Flags: 
Precursor
Length=602

 GENE ID: 24693 Ptgs1 | prostaglandin-endoperoxide synthase 1
[Rattus norvegicus] (Over 10 PubMed links)

 Score = 1023 bits (2645),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 508/576 (88%), Positives = 540/576 (93%), Gaps = 0/576 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
             D G P+PVNPCCYYPCQ+QG+CVRFGLD YQCDCTRTGYSGPNCTIP +WTWLR+SLRP
Sbjct  27   TDAGVPSPVNPCCYYPCQNQGVCVRFGLDHYQCDCTRTGYSGPNCTIPEIWTWLRSSLRP  86

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SPSFTHFLLTHG W WEFVNATFIRE+LMRLV+TVRSNLIPSPPTYN+AHDYISWESFSN
Sbjct  87   SPSFTHFLLTHGYWIWEFVNATFIREVLMRLVITVRSNLIPSPPTYNTAHDYISWESFSN  146

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILPSVPKDCPTPMGTKGKKQLPD  LLA+R LLRR+FIP PQGTN++FAFFAQH
Sbjct  147  VSYYTRILPSVPKDCPTPMGTKGKKQLPDIHLLAQRLLLRREFIPGPQGTNVLFAFFAQH  206

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGD+LERQY LRLFKDGKLKYQVLDGE+YPP
Sbjct  207  FTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDSLERQYHLRLFKDGKLKYQVLDGEVYPP  266

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SVE+A VLM YP G+PP+ QMAVGQEVFGLLPGLML++T+WLREHNRVCDLLK EHPTW 
Sbjct  267  SVEQASVLMRYPPGVPPEKQMAVGQEVFGLLPGLMLFSTIWLREHNRVCDLLKEEHPTWD  326

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLILIGETIKI+IEEYVQ LSGYFLQLKFDPELLF  QFQYRNRIA+EFNHL
Sbjct  327  DEQLFQTTRLILIGETIKIIIEEYVQHLSGYFLQLKFDPELLFRAQFQYRNRIALEFNHL  386

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF+VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQ AGRIGGGRN D+H+
Sbjct  387  YHWHPLMPDSFQVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQRAGRIGGGRNFDYHV  446

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            LHVA DVI+ESREMRLQ FNEYRKRFG+KPYTSFQE  GEKEMAAELEELYGDIDALEFY
Sbjct  447  LHVAEDVIKESREMRLQSFNEYRKRFGLKPYTSFQEFTGEKEMAAELEELYGDIDALEFY  506

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGL+LEKC PNS+FGESMIE+GAPFSLKGLLGNPICSPEYWKPSTFGG+VGFNIV TA+L
Sbjct  507  PGLMLEKCQPNSLFGESMIEMGAPFSLKGLLGNPICSPEYWKPSTFGGDVGFNIVNTASL  566

Query  564  KKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            KKLVCLNTKTCPYVSFRVPD   DDG    RPSTEL
Sbjct  567  KKLVCLNTKTCPYVSFRVPDYPGDDGSVFVRPSTEL  602


>sp|O62698.2|PGH2_BOVIN  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 282023 PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin
G/H synthase and cyclooxygenase) [Bos taurus] (Over 10 PubMed links)

 Score =  751 bits (1939),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 363/554 (65%), Positives = 451/554 (81%), Gaps = 1/554 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC +PCQ++G+C+  G D+Y+CDCTRTG+ G NCT P   T ++  L+P+P+  H++
Sbjct  18   ANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYI  77

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN  +F+R M+MR VLT RS+LI SPPTYN  + Y SWE+FSN+SYYTR 
Sbjct  78   LTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRA  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP VP DCPTPMG KG+K+LPD++ + ++ LLRRKFIPDPQGTNLMFAFFAQHFTHQFFK
Sbjct  138  LPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFK  197

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  + GP FTK   HGVDL HIYG++LERQ++LRLFKDGK+KYQ+++GEMYPP+V++  V
Sbjct  198  TDFERGPAFTKGKNHGVDLSHIYGESLERQHKLRLFKDGKMKYQMINGEMYPPTVKDTQV  257

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP WGDEQLFQT
Sbjct  258  EMIYPPHVPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQT  317

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  318  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLL  377

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD F++  QEY+Y+QF++N S+L+++G+   V++F+RQ AGR+ GGRN+   +  V+   
Sbjct  378  PDVFQIDGQEYNYQQFIYNNSVLLEHGLTQFVESFTRQRAGRVAGGRNLPVAVEKVSKAS  437

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I +SREM+ Q FNEYRKRF +KPY SF+EL GEKEMAAELE LYGDIDA+EFYP LL+EK
Sbjct  438  IDQSREMKYQSFNEYRKRFLVKPYESFEELTGEKEMAAELEALYGDIDAMEFYPALLVEK  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGE+M+E GAPFSLKGL+GNPICSPEYWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct  498  PRPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSN  557

Query  571  TKTCPYVSFRVPDA  584
             K CP+ SF V D 
Sbjct  558  VKGCPFTSFSVQDT  571


>sp|P27607.1|PGH2_CHICK  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
AltName: Full=Mitogen-inducible PGHS; Flags: Precursor
Length=603

 GENE ID: 396451 PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin
G/H synthase and cyclooxygenase) [Gallus gallus] (10 or fewer PubMed links)

 Score =  751 bits (1938),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 365/550 (66%), Positives = 451/550 (82%), Gaps = 1/550 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G+C+  G DRY+CDCTRTGY G NCT P  +TWL+  L+P+P+  H++L
Sbjct  19   NPCCSLPCQNRGVCMTTGFDRYECDCTRTGYYGENCTTPEFFTWLKLILKPTPNTVHYIL  78

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W  +N  +F+R+ +MR VLT RS+LI SPPTYNS + Y SWE++SN+SYYTR L
Sbjct  79   THFKGVWNIINNISFLRDTIMRYVLTSRSHLIDSPPTYNSDYSYKSWEAYSNLSYYTRSL  138

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P V  DCPTPMG KGKK+LPD++L+  +FLLRRKFIPDPQGTN+MF FFAQHFTHQFFKT
Sbjct  139  PPVGHDCPTPMGVKGKKELPDSKLIVEKFLLRRKFIPDPQGTNVMFTFFAQHFTHQFFKT  198

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GPGFTKA GHGVDL HIYG+ LERQ +LRL KDGKLKYQ++DGEMYPP+V++    
Sbjct  199  DHKKGPGFTKAYGHGVDLNHIYGETLERQLKLRLRKDGKLKYQMIDGEMYPPTVKDTQAE  258

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  +P   Q +VGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DEQLFQTT
Sbjct  259  MIYPPHVPEHLQFSVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDEQLFQTT  318

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRIA EFN LYHWHPL+P
Sbjct  319  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQRFQYQNRIAAEFNTLYHWHPLLP  378

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F++ +QEY+++QFL+N S+++++G+  +V +FS+Q AGR+ GG+N+   +  VA   I
Sbjct  379  DTFQIHNQEYTFQQFLYNNSIMLEHGLSHMVKSFSKQSAGRVAGGKNVPAAVQKVAKASI  438

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             +SR+MR Q  NEYRKRF +KP+ SF+EL GEKEMAAELEELYGDIDA+E YPGLL+EK 
Sbjct  439  DQSRQMRYQSLNEYRKRFMLKPFKSFEELTGEKEMAAELEELYGDIDAMELYPGLLVEKP  498

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             P +IFGE+M+EIGAPFSLKGL+GN ICSPEYWKPSTFGG+VGF I+ TA+L+KL+C N 
Sbjct  499  RPGAIFGETMVEIGAPFSLKGLMGNTICSPEYWKPSTFGGKVGFEIINTASLQKLICNNV  558

Query  572  KTCPYVSFRV  581
            K CP+ +F V
Sbjct  559  KGCPFTAFHV  568


>sp|O02768.1|PGH2_RABIT  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 100009248 COX-2 | cyclooxygenase-2 [Oryctolagus cuniculus]
(10 or fewer PubMed links)

 Score =  749 bits (1933),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 362/553 (65%), Positives = 448/553 (81%), Gaps = 1/553 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC  PCQ++G+C+  G D+Y+CDCTRTG+ G NC+ P   T ++  L+P+P   H++
Sbjct  18   ANPCCSNPCQNRGVCMTMGFDQYKCDCTRTGFYGENCSTPEFLTRIKLLLKPTPDTVHYI  77

Query  92   LTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN+  F+R  +M+ VLT RS++I SPPTYN  ++Y SWE+FSN+SYYTR 
Sbjct  78   LTHFKGVWNIVNSIPFLRNSIMKYVLTSRSHMIDSPPTYNVHYNYKSWEAFSNLSYYTRA  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP V  DCPTPMG KGKK+LPD++ +  + LLRRKFIPDPQGTN+MFAFFAQHFTHQFFK
Sbjct  138  LPPVADDCPTPMGVKGKKELPDSKDVVEKLLLRRKFIPDPQGTNMMFAFFAQHFTHQFFK  197

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  K GP FTK LGHGVDL HIYG+ L+RQ++LRLFKDGK+KYQV+DGE+YPP+V++  V
Sbjct  198  TDLKRGPAFTKGLGHGVDLNHIYGETLDRQHKLRLFKDGKMKYQVIDGEVYPPTVKDTQV  257

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  IP   Q AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DEQLFQT
Sbjct  258  EMIYPPHIPAHLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDEQLFQT  317

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  318  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLL  377

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F++  Q+Y+Y+QFL+N S+L+++G+   V++F+RQIAGR+ GGRN+   +  VA   
Sbjct  378  PDTFQIDDQQYNYQQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPPAVQKVAKAS  437

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I +SR+M+ Q  NEYRKRF +KPY SF+EL GEKEMAAELE LYGDIDA+E YP LL+E+
Sbjct  438  IDQSRQMKYQSLNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAVELYPALLVER  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGESM+E+GAPFSLKGL+GNPICSP YWKPSTFGGEVGF IV TA+++ L+C N
Sbjct  498  PRPDAIFGESMVEMGAPFSLKGLMGNPICSPNYWKPSTFGGEVGFKIVNTASIQSLICNN  557

Query  571  TKTCPYVSFRVPD  583
             K CP+ SF VPD
Sbjct  558  VKGCPFTSFNVPD  570


>sp|P79208.1|PGH2_SHEEP  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=603

 GENE ID: 443460 PGHS-2 | prostaglandin H synthase-2 [Ovis aries]
(10 or fewer PubMed links)

 Score =  748 bits (1932),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 362/554 (65%), Positives = 448/554 (80%), Gaps = 1/554 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC +PCQ++G+C+  G D+Y+CDCTRTG+ G NCT P   T ++  L+P+P   H++
Sbjct  17   ANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYI  76

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN  +F+R M+MR VLT RS+LI SPPTYN  + Y SWE+FSN+SYYTR 
Sbjct  77   LTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRA  136

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP VP DCPTPMG KG+K+LPD++ + ++ LLRRKFIPDPQGTNLMFAFFAQHFTHQFFK
Sbjct  137  LPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFK  196

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  + GP FTK   HGVDL H+YG++LERQ+  RLFKDGK+KYQ+++GEMYPP+V++  V
Sbjct  197  TDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQV  256

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  IP   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP WGDEQLFQT
Sbjct  257  EMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQT  316

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  317  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLL  376

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD F++  QEY+Y+QF++N S+L+++GV   V++F+RQIAGR+ G RN+   +  V+   
Sbjct  377  PDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKAS  436

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            + +SREM+ Q FNEYRKRF +KPY SF+EL GEKEMAAELE LYGDIDA+E YP LL+EK
Sbjct  437  LDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEK  496

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGE+M+E GAPFSLKGL+GNPICSPEYWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct  497  PAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSN  556

Query  571  TKTCPYVSFRVPDA  584
             K CP+ SF V DA
Sbjct  557  VKGCPFTSFSVQDA  570


>sp|P35354.2|PGH2_HUMAN  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 5743 PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H
synthase and cyclooxygenase) [Homo sapiens] (Over 100 PubMed links)

 Score =  744 bits (1920),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 357/553 (64%), Positives = 446/553 (80%), Gaps = 1/553 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC +PCQ++G+C+  G D+Y+CDCTRTG+ G NC+ P   T ++  L+P+P+  H++
Sbjct  18   ANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYI  77

Query  92   LTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH + FW  VN   F+R  +M  VLT RS+LI SPPTYN+ + Y SWE+FSN+SYYTR 
Sbjct  78   LTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRA  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP VP DCPTP+G KGKKQLPD+  +  + LLRRKFIPDPQG+N+MFAFFAQHFTHQFFK
Sbjct  138  LPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFK  197

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  K GP FT  LGHGVDL HIYG+ L RQ +LRLFKDGK+KYQ++DGEMYPP+V++   
Sbjct  198  TDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQA  257

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP WGDEQLFQT
Sbjct  258  EMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQT  317

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  318  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLL  377

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F++  Q+Y+Y+QF++N S+L+++G+   V++F+RQIAGR+ GGRN+   +  V+   
Sbjct  378  PDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQAS  437

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I +SR+M+ Q FNEYRKRF +KPY SF+EL GEKEM+AELE LYGDIDA+E YP LL+EK
Sbjct  438  IDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEK  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGE+M+E+GAPFSLKGL+GN ICSP YWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct  498  PRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNN  557

Query  571  TKTCPYVSFRVPD  583
             K CP+ SF VPD
Sbjct  558  VKGCPFTSFSVPD  570


>sp|Q05769.1|PGH2_MOUSE  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
AltName: Full=Glucocorticoid-regulated inflammatory cyclooxygenase; 
AltName: Full=Gripghs; AltName: Full=TIS10 protein; 
AltName: Full=Macrophage activation-associated marker protein 
P71/73; AltName: Full=PES-2; Flags: Precursor
Length=604

 GENE ID: 19225 Ptgs2 | prostaglandin-endoperoxide synthase 2 [Mus musculus]
(Over 100 PubMed links)

 Score =  740 bits (1910),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 362/561 (64%), Positives = 446/561 (79%), Gaps = 1/561 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            A  G     NPCC  PCQ++G C+  G D+Y+CDCTRTG+ G NCT P   T ++  L+P
Sbjct  10   AALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKP  69

Query  84   SPSFTHFLLTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFS  142
            +P+  H++LTH +  W  VN   F+R ++M+ VLT RS LI SPPTYN  + Y SWE+FS
Sbjct  70   TPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFS  129

Query  143  NVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaq  202
            N+SYYTR LP V  DCPTPMG KG K+LPD++ +  + LLRR+FIPDPQG+N+MFAFFAQ
Sbjct  130  NLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQ  189

Query  203  hfthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYP  262
            HFTHQFFKT  K GPGFT+ LGHGVDL HIYG+ L+RQ++LRLFKDGKLKYQV+ GE+YP
Sbjct  190  HFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYP  249

Query  263  PSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTW  322
            P+V++  V M YP  IP   Q AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W
Sbjct  250  PTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEW  309

Query  323  GDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNH  382
            GDEQLFQT+RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN 
Sbjct  310  GDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNT  369

Query  383  LYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHH  442
            LYHWHPL+PD+F +  QEYS++QFL+N S+L+++G+   V++F+RQIAGR+ GGRN+   
Sbjct  370  LYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIA  429

Query  443  ILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEF  502
            +  VA   I +SREM+ Q  NEYRKRF +KPYTSF+EL GEKEMAAEL+ LY DID +E 
Sbjct  430  VQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMEL  489

Query  503  YPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTAT  562
            YP LL+EK  P++IFGE+M+E+GAPFSLKGL+GNPICSP+YWKPSTFGGEVGF I+ TA+
Sbjct  490  YPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTAS  549

Query  563  LKKLVCLNTKTCPYVSFRVPD  583
            ++ L+C N K CP+ SF V D
Sbjct  550  IQSLICNNVKGCPFTSFNVQD  570


>sp|P70682.1|PGH2_CAVPO  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 100135607 Ptgs2 | prostaglandin-endoperoxide synthase 2
[Cavia porcellus] (10 or fewer PubMed links)

 Score =  738 bits (1906),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 360/552 (65%), Positives = 441/552 (79%), Gaps = 1/552 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G C+  G DRY+CDCTRTGY G NCT P   T ++  L+P+P+  H++L
Sbjct  19   NPCCSNPCQNRGECLSVGFDRYKCDCTRTGYYGENCTTPEFLTRIKLLLKPTPNTVHYIL  78

Query  93   THGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W  VN   F+R  +M  VLT RS+LI SPPTYN+ + Y SWE+FSN+SYYTR L
Sbjct  79   THFKGVWNIVNNIPFLRNAIMIYVLTSRSHLIDSPPTYNAHYGYKSWEAFSNLSYYTRAL  138

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P V  DCPTPMG KGKK+LPD+  +  + LLRRKFIPDPQGTN+MFAFFAQHFTHQFFK+
Sbjct  139  PPVADDCPTPMGVKGKKELPDSNEVLEKVLLRRKFIPDPQGTNMMFAFFAQHFTHQFFKS  198

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GP FT  L HGVDL HIYG+ L+RQ++LRLFKDGK+KYQ++DGEMYPP+V+E  V 
Sbjct  199  DQKRGPAFTTGLAHGVDLSHIYGETLDRQHKLRLFKDGKMKYQIIDGEMYPPTVKETQVE  258

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  IP  ++ AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DE+LFQT+
Sbjct  259  MMYPPYIPEHARFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDERLFQTS  318

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+P
Sbjct  319  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLP  378

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F++  Q Y+++QFL+N S+LV++G+   V++F++QIAGR+ GGRN+   +  VA   I
Sbjct  379  DTFQIDDQVYNFQQFLYNNSILVEHGLTQFVESFTKQIAGRVAGGRNVPLAVQRVAKASI  438

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
              SR+M+ Q  NEYRKRF MKPYTSF+EL GEKEMAA LE LYGDIDA+E YP LL+EK 
Sbjct  439  EHSRKMKYQSLNEYRKRFLMKPYTSFEELTGEKEMAAGLEALYGDIDAMELYPALLVEKP  498

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             P++IFGE+M+E+GAPFSLKGL+GNPICSP YWKPSTFGGEVGF IV TA+++ L+C N 
Sbjct  499  RPDAIFGETMVEMGAPFSLKGLMGNPICSPHYWKPSTFGGEVGFQIVNTASIQSLICNNV  558

Query  572  KTCPYVSFRVPD  583
            K CP  +F +PD
Sbjct  559  KGCPVTAFNLPD  570


>sp|O19183.1|PGH2_HORSE  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 791253 PGHS2 | prostaglandin G/H synthase-2 [Equus caballus]
(10 or fewer PubMed links)

 Score =  738 bits (1904),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 358/553 (64%), Positives = 446/553 (80%), Gaps = 1/553 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC  PCQ++G+C+  G D+YQCDCTRTG+ G NC+ P   T ++  L+P+P+  H++
Sbjct  18   ANPCCSNPCQNRGVCMSVGFDQYQCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYI  77

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN+  F+R  +M+ VL  RS+LI SPPTYN+ + Y SWESFSN+SYYTR 
Sbjct  78   LTHFKGVWNIVNSFPFLRNAVMKYVLVSRSHLIESPPTYNAQYGYKSWESFSNLSYYTRA  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP V   CPTPMG KGKK+LPD++ +  +FLLRRKFIPDPQGTN+MFAFFAQHFTHQFFK
Sbjct  138  LPPVADGCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGTNMMFAFFAQHFTHQFFK  197

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T  K GP FTK LGHGVDL HIYG+ L+RQ++LRLFKDGK+KYQ+++GE+YPP+V++  V
Sbjct  198  TDPKRGPAFTKGLGHGVDLSHIYGETLDRQHKLRLFKDGKMKYQIINGEVYPPTVKDTQV  257

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  IP   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DE+LFQT
Sbjct  258  EMIYPPHIPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDERLFQT  317

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+
Sbjct  318  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLL  377

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F++  QEY+++QFL+N S+L+++G+   V++FSRQIAGR+ GGRN+      +A   
Sbjct  378  PDTFQIDDQEYNFQQFLYNNSILLEHGLTQFVESFSRQIAGRVAGGRNVPAAAQKIAKAS  437

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I +SREM+ Q  NEYRKRF + PY SF+EL GEKEMAAELE LYGDIDA+E YP LL+EK
Sbjct  438  IDQSREMKYQSLNEYRKRFRLTPYKSFEELTGEKEMAAELEALYGDIDAMELYPALLVEK  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P++IFGE+M+E+GAPFSLKGLLGNPICSP+YWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct  498  PRPDAIFGETMVELGAPFSLKGLLGNPICSPDYWKPSTFGGEVGFKIINTASIQSLICNN  557

Query  571  TKTCPYVSFRVPD  583
             K CP+ +F V D
Sbjct  558  VKGCPFTAFSVQD  570


>sp|P35355.1|PGH2_RAT  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 GENE ID: 29527 Ptgs2 | prostaglandin-endoperoxide synthase 2
[Rattus norvegicus] (Over 100 PubMed links)

 Score =  732 bits (1890),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 356/552 (64%), Positives = 444/552 (80%), Gaps = 1/552 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G C+  G D+Y+CDCTRTG+ G NCT P   T ++  L+P+P+  H++L
Sbjct  19   NPCCSNPCQNRGECMSIGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYIL  78

Query  93   THGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W  VN   F+R  +MR VLT RS+LI SPPTYN  + Y SWE+FSN+SYYTR L
Sbjct  79   THFKGVWNIVNNIPFLRNSIMRYVLTSRSHLIDSPPTYNVHYGYKSWEAFSNLSYYTRAL  138

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P V  DCPTPMG KG K+LPD++ +  + LLRR+FIPDPQGTN+MFAFFAQHFTHQFFKT
Sbjct  139  PPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGTNMMFAFFAQHFTHQFFKT  198

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GPGFT+ LGHGVDL H+YG+ L+RQ++LRLF+DGKLKYQV+ GE+YPP+V++  V 
Sbjct  199  DQKRGPGFTRGLGHGVDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQVD  258

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DE+LFQT+
Sbjct  259  MIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTS  318

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  QFQY+NRIA EFN LYHWHPL+P
Sbjct  319  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLP  378

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F +  QEY+++QFL+N S+L+++G+   V++F+RQIAGR+ GGRN+   +  VA   I
Sbjct  379  DTFNIEDQEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRVAGGRNVPIAVQAVAKASI  438

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             +SREM+ Q  NEYRKRF +KPYTSF+EL GEKEMAAEL+ LY DIDA+E YP LL+EK 
Sbjct  439  DQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYHDIDAMELYPALLVEKP  498

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             P++IFGE+M+E+GAPFSLKGL+GNPICSP+YWKPSTFGGEVGF I+ TA+++ L+C N 
Sbjct  499  RPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFRIINTASIQSLICNNV  558

Query  572  KTCPYVSFRVPD  583
            K CP+ SF V D
Sbjct  559  KGCPFASFNVQD  570


>sp|O62725.1|PGH2_MUSVI  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
Flags: Precursor
Length=604

 Score =  707 bits (1824),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 343/556 (61%), Positives = 436/556 (78%), Gaps = 1/556 (0%)

Query  29   PTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFT  88
            P   NPCC  PCQ+QG+C+  G D+Y CDC+RTG+ G NC+ P   T ++  L+P+P+  
Sbjct  15   PHAANPCCSNPCQNQGVCMSIGFDQYMCDCSRTGFYGENCSTPEFLTRVKLLLKPTPNTV  74

Query  89   HFLLTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYY  147
            H++LTH +  W  VN   F+ +++M+ V T RS+ I  PPTYN  + Y SWE+FSN+SYY
Sbjct  75   HYILTHFKGVWNIVNKIPFLADVIMKYVRTSRSHCIEPPPTYNVHYAYKSWEAFSNLSYY  134

Query  148  TRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthq  207
            TR LP V  DCPTPMG KGKK+LPD++ +  +FLLRRKFIPDPQGTN+MFAFFAQHFTHQ
Sbjct  135  TRALPPVADDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGTNMMFAFFAQHFTHQ  194

Query  208  ffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEE  267
            FFKT  K GPGFTK LGHGVDL H+YG+ L+RQ++LRLFKDGK+KYQV+DGE+YPP+V++
Sbjct  195  FFKTDHKRGPGFTKGLGHGVDLSHVYGETLDRQHKLRLFKDGKMKYQVIDGEVYPPTVKD  254

Query  268  APVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQL  327
              V M YP  +P   + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK E   W DE+L
Sbjct  255  TQVEMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEQGEWDDERL  314

Query  328  FQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWH  387
            F+ +RLILIGETIKIVIE+YV+ LSGY   LKFDPELLF  QFQY+NRIA EFN LYHWH
Sbjct  315  FRRSRLILIGETIKIVIEDYVRHLSGYHFSLKFDPELLFNQQFQYQNRIAAEFNTLYHWH  374

Query  388  PLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVA  447
            PL+PD+ ++  QEY+++QF++N S+L+++G+    ++FSRQIAGR+ GGRN+   +    
Sbjct  375  PLLPDTLQIDDQEYNFQQFVYNNSILLEHGLTQFGESFSRQIAGRVAGGRNVPAAVQQEQ  434

Query  448  VDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLL  507
               I +SR+M+ Q  NEYRKRF +KPY SF+EL GEKEMA EL+ LY DIDA+E YP LL
Sbjct  435  RASIDQSRQMKYQSLNEYRKRFSVKPYASFEELTGEKEMAGELKALYQDIDAMELYPALL  494

Query  508  LEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLV  567
            +EK  P++IFGE+M+EIGAPFSLKGL+GNPICSP+YWKPS FGGEVGF I+ TA+++ L+
Sbjct  495  VEKPRPDAIFGETMVEIGAPFSLKGLMGNPICSPDYWKPSHFGGEVGFKIINTASIQSLI  554

Query  568  CLNTKTCPYVSFRVPD  583
            C N K CP+ +F V D
Sbjct  555  CNNVKGCPFTAFSVQD  570


>sp|Q7QH73.3|PERC_ANOGA  RecName: Full=Chorion peroxidase; Contains: RecName: Full=Chorion 
peroxidase light chain; Contains: RecName: Full=Chorion 
peroxidase heavy chain; Flags: Precursor
Length=767

 Score = 83.2 bits (204),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 103/409 (25%), Positives = 167/409 (40%), Gaps = 53/409 (12%)

Query  213  GKMGPGFTKALG---HGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAP  269
            GK   G+ K L    H +D   +YG N      LR F+ G+L+     GE   P      
Sbjct  350  GKCRLGYGKQLNRVTHFIDGSAVYGSNEALAASLRTFEGGRLRSSFPTGEELLPFARTRA  409

Query  270  VLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQ  329
                + +          G +    +  L    TL+LREHNRV   L A +  W DE+L+Q
Sbjct  410  ACEPWAKAC-----FRAGDDRVNQIVSLTEMHTLFLREHNRVATALAALNRHWDDERLYQ  464

Query  330  TTRLILIGETIKIVIEEYVQQLSGYFLQLK-------------FDPEL-------LFGVQ  369
             TR I+     KI   EY+  + G+    +             + P++       L G  
Sbjct  465  ETRRIVGAVMQKIFYNEYLPSIVGHSKARQYGLLDSHGEQTDFYSPDVKPAVFNELSGAA  524

Query  370  FQYRNRI---AMEFNHLYHWHPLMP--DSFKVGS---QEYSYEQFLFNTSMLVDYGVEAL  421
            F++ +     A    H +    L+P  + F   S   Q   ++ FLF+   L+D   + L
Sbjct  525  FRFGHSTVDGAFLIQHRHRRTELVPIQEVFLNPSRLLQRSFFDDFLFS---LMDQPQQQL  581

Query  422  VDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELV  481
             D+ +  +   +  GRN     L  A   I+  R+  L+P+N+YR   G++  TSF++  
Sbjct  582  DDSITFGLTRLLFAGRNPFGSDL--ASLNIQRGRDHALRPYNDYRSWAGLERLTSFEQF-  638

Query  482  GEKEMAAELEELYGDIDALEFYPGLLLE-KCHPNSIFGESMIEIGAPFSLKGLLGNP--I  538
                + A L  +Y   D ++ + G LLE      ++FGE+   I +    +   G+    
Sbjct  639  --GPVGARLASVYEFPDDVDLWVGGLLEPPTQDGALFGETFAAIISEQFARLKFGDRYYY  696

Query  539  CSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTK-----TCPYVSFRVP  582
             +     P  F GE    + K  +L  ++C N       + P  +FR P
Sbjct  697  TNGPRTNPGFFTGEQLRELSKV-SLASVICANLDQADGFSAPRDAFRQP  744


>sp|P82600.3|PERC_AEDAE  RecName: Full=Chorion peroxidase; Contains: RecName: Full=Chorion 
peroxidase light chain; Contains: RecName: Full=Chorion 
peroxidase heavy chain; Flags: Precursor
Length=790

 Score = 78.6 bits (192),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 79/324 (24%), Positives = 141/324 (43%), Gaps = 33/324 (10%)

Query  225  HGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQM  284
            H +D   +YG   +   +LR F+ G+LK      + +P  +E  P   +    +P     
Sbjct  387  HFLDASTVYGSTNDVAAELRAFQQGRLK------DSFPNGIELLPFARNRTACVPWARVC  440

Query  285  AVGQEV-FGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIV  343
              G ++    L GL +  TL++REHNR+   L   +P W DE+L+Q  R ILI E   +V
Sbjct  441  YEGGDIRTNQLLGLTMVHTLFMREHNRLAVGLSKINPHWDDERLYQEARRILIAEYQNVV  500

Query  344  IEEYVQQLSGYFLQLKFDPELLFGVQFQY-----RNRIAMEFNHLYHW--HPLMPDSFKV  396
              E++  L G+    +      F     Y     R     E     H   H L+   F+ 
Sbjct  501  YNEFLPILLGHERVQQLGLADPFDTYTNYYDPNLRPMTLAEVGAAAHRYGHSLVEGFFRF  560

Query  397  GSQEYSYEQF----LFN--TSMLVDYGVEALVDAFSRQIAGRI------GGGRNMDHHIL  444
             ++E   E      +FN  +  L     + ++ +F++Q   ++      G  R +     
Sbjct  561  LTRESPPEDVFIKDIFNDPSKTLEPNSFDVMMFSFNQQPMEQMDRFLTYGLTRFLFKERK  620

Query  445  HVAVDV----IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDAL  500
                D+    I+  R+  ++P+N+YR+  G+   T F +L    E+ A L ++Y   D +
Sbjct  621  PFGSDLASLNIQRGRDFAVRPYNDYREWAGLGRITDFNQL---GEVGALLAQVYESPDDV  677

Query  501  EFYPGLLLEKCHPNSIFGESMIEI  524
            + +PG +LE     ++ G + + +
Sbjct  678  DLWPGGVLEPPAEGAVVGSTFVAL  701


>sp|O61213.2|DUOX1_CAEEL  RecName: Full=Dual oxidase 1; Short=DUOX1; AltName: Full=NADPH 
thyroid oxidase 1; AltName: Full=Blistered cuticle protein 
3; Flags: Precursor
Length=1497

 GENE ID: 171608 bli-3 | BLIstered cuticle [Caenorhabditis elegans]
(10 or fewer PubMed links)

 Score = 73.6 bits (179),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 93/334 (27%), Positives = 146/334 (43%), Gaps = 50/334 (14%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLK-----YQVLDGEMYPPSVEEAPVLMHYPRGIPPQ  281
            +D   IYG        LR FK G+L      Y  L+    P +   AP  +H  R + P 
Sbjct  170  IDGSFIYGTTQPWVSSLRSFKQGRLAEGVPGYPPLNNPHIPLN-NPAPPQVH--RLMSPD  226

Query  282  SQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIK  341
                +G       PGL+ +  +  R HN   + +  EHP W DEQ+FQ  R ++I    K
Sbjct  227  RLFMLGDSRVNENPGLLSFGLILFRWHNYNANQIHREHPDWTDEQIFQAARRLVIASMQK  286

Query  342  IVIEEYVQQLSGYFLQL----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSF---  394
            I+  ++V  L G  ++L    K+ P +  G+   +    A  F      H ++P +    
Sbjct  287  IIAYDFVPGLLGEDVRLSNYTKYMPHVPPGISHAF-GAAAFRFP-----HSIVPPAMLLR  340

Query  395  KVGSQ-EYSYE----------QFLFNTSMLV-DYGVEALVDAFSRQIAGR-----IGGGR  437
            K G++ E+  E          Q  +N   +V +Y V+ ++   + QIA R     +   R
Sbjct  341  KRGNKCEFRTEVGGYPALRLCQNWWNAQDIVKEYSVDEIILGMASQIAERDDNIVVEDLR  400

Query  438  N-----MDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYT--SFQELVGEKEMAA--  488
            +     M    L V    I   R+  + P+NE R+ FG+ P T  +  E   +K  A   
Sbjct  401  DYIFGPMHFSRLDVVASSIMRGRDNGVPPYNELRRTFGLAPKTWETMNEDFYKKHTAKVE  460

Query  489  ELEELY-GDIDALEFYPGLLLE--KCHPNSIFGE  519
            +L+ELY G+I  L+ Y G +LE  +  P  +F E
Sbjct  461  KLKELYGGNILYLDAYVGGMLEGGENGPGELFKE  494


>sp|Q9UUS2.1|LIDS_GAEGR  RecName: Full=Linoleate diol synthase; AltName: Full=Linoleate 
(8R)-dioxygenase; Short=Linoleate 8-dioxygenase
Length=978

 Score = 68.2 bits (165),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 79/349 (22%), Positives = 131/349 (37%), Gaps = 91/349 (26%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAV  286
            +DL  +YG N + Q  +R  KDG LK                                  
Sbjct  222  LDLSPLYGRNHDEQMAVRTGKDGLLKPDTFSS----------------------------  253

Query  287  GQEVFGLLPGLMLYATLWLREHNRVCDLL-------KAEHPT-------WG--DEQLFQT  330
             + V G  PG+  +  ++ R HN V   L       + + PT       W   D  LFQT
Sbjct  254  -KRVIGFPPGVGAFLIMFNRFHNYVVTQLAKINEGGRFKRPTTPDDTAGWETYDNSLFQT  312

Query  331  TRLILIGETIKIVIEEYVQ---QLSGYFLQLKFDPELLFGVQFQYR-------NRIAMEF  380
             RLI  G  I IV+ +YV+    L+        DP    G     +       N++++EF
Sbjct  313  GRLITCGLYINIVLGDYVRTILNLNRANTTWNLDPRTKEGKSLLSKPTPEAVGNQVSVEF  372

Query  381  NHLYHWHPLMPDSFK----------VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIA  430
            N +Y WH  + +             +G Q+ +  +       L  +      +   R +A
Sbjct  373  NLIYRWHCTISERDDKWTTNAMREALGGQDPATAKMEDVMRALGMFEKNIPDEPEKRTLA  432

Query  431  G--RIGGGRNMDHHILHV----------------------AVDV--IRESREMRLQPFNE  464
            G  R   G   D  ++ +                      A+++  I++SR   +   NE
Sbjct  433  GLTRQSDGAFDDTELVKILQESIEDVAGAFGPNHVPACMRAIEILGIKQSRTWNVATLNE  492

Query  465  YRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHP  513
            +R+  G+ P+ SF  +  + ++   L ++Y   DA+E YPG++ E   P
Sbjct  493  FRQFIGLTPHDSFYHMNPDPKICKILAQMYDSPDAVELYPGIMAEAAKP  541


>sp|Q92626.2|PXDN_HUMAN  RecName: Full=Peroxidasin homolog; AltName: Full=Vascular peroxidase 
1; AltName: Full=Melanoma-associated antigen MG50; AltName: 
Full=p53-responsive gene 2 protein; Flags: Precursor
Length=1479

 GENE ID: 7837 PXDN | peroxidasin homolog (Drosophila) [Homo sapiens]
(10 or fewer PubMed links)

 Score = 66.2 bits (160),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 77/336 (22%), Positives = 141/336 (41%), Gaps = 41/336 (12%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
             GL    TLW REHNR+   L   +P W  + ++  TR I+  E   I  + ++ ++ G  
Sbjct  983   GLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEV  1042

Query  356   LQLK------FDPELLFGVQFQYRNRIAMEFNHLYHWHPL---MPDSFKVGSQEY-SYEQ  405
                       +DP +  G+ F      A  F H    +PL   + ++F+  +Q++    +
Sbjct  1043  GMRTLGEYHGYDPGINAGI-FNAFATAAFRFGHTL-VNPLLYRLDENFQPIAQDHLPLHK  1100

Query  406   FLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHVAVD  449
               F+   +V+   E  +D   R + G  G  R               +M H + L +A  
Sbjct  1101  AFFSPFRIVN---EGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAI  1157

Query  450   VIRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGL  506
              I+  R+  + P+++YR    +    +F++L  E    E+  +L+ LYG    ++ +P L
Sbjct  1158  NIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPAL  1217

Query  507   LLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKL  566
             ++E   P S  G +++ + +    +   G+ +    Y  P  F        +K  +L ++
Sbjct  1218  VVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLW---YENPGVF-SPAQLTQIKQTSLARI  1273

Query  567   VCLNTKTCPYVS---FRVPDASQDDGPAVERPSTEL  599
             +C N      V    FRV +     G   E P  +L
Sbjct  1274  LCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDL  1309


>sp|Q8HZK3.1|DUOX1_PIG  RecName: Full=Dual oxidase 1; Flags: Precursor
Length=1553

 GENE ID: 397177 DUOX1 | dual oxidase 1 [Sus scrofa] (10 or fewer PubMed links)

 Score = 63.9 bits (154),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 75/296 (25%), Positives = 116/296 (39%), Gaps = 57/296 (19%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYP-------RGIP  279
            +D   IYG +     +LR F  G+L       +   P   + P+ M  P       RG  
Sbjct  173  LDGSAIYGSSHSWSDELRSFSGGQLAS---GPDPAFPRQAQDPLFMWTPPDPATGQRG--  227

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
            PQ   A G E     P L     LW R HN     L  EHP WGDE+LFQ  R  +I   
Sbjct  228  PQGLYAFGAEQGNREPFLQALGLLWFRYHNLCAQKLAREHPLWGDEELFQHARKRVIATY  287

Query  340  IKIVIEEYV--------QQLSGY--FLQLKFDPELLFGV-QF--------QYRNRIAMEF  380
              I + E++        Q+ +GY  FL     PE L    QF         Y    +  F
Sbjct  288  QSITMYEWLPSFLRKMPQEYTGYRPFLDPSISPEFLAASEQFFSTMVPPGVYMRNASCHF  347

Query  381  NHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMD  440
              + + +  +  + +V +  +S E    + ++     V+AL+   + QIA R       D
Sbjct  348  QGVINRNSSVSRALRVCNSYWSRE----HPNLQRAEDVDALLLGMASQIAER------ED  397

Query  441  HHILHVAVD----------------VIRESREMRLQPFNEYRKRFGMKPYTSFQEL  480
            H ++    D                 ++  R++ L  + + R R G+ P T +Q++
Sbjct  398  HMVVEDVQDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARARLGLPPVTRWQDI  453


>sp|Q9VEG6.2|PERC_DROME  RecName: Full=Chorion peroxidase; AltName: Full=Peroxinectin-related 
protein; Short=Dpxt; Contains: RecName: Full=Chorion 
peroxidase light chain; Contains: RecName: Full=Chorion peroxidase 
heavy chain; Flags: Precursor
Length=831

 Score = 63.2 bits (152),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 96/415 (23%), Positives = 158/415 (38%), Gaps = 77/415 (18%)

Query  216  GPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQ---------VLDGEMYPPSVE  266
            G   TK + H VD   +YG + E    LR F+ G+L+           + + +   PS E
Sbjct  394  GKQLTK-VTHFVDASPVYGSSDEASRSLRAFRGGRLRMMNDFGRDLLPLTNDKKACPSEE  452

Query  267  EAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYAT------------------LWLREH  308
                  H        S  ++   VF ++  L+ Y T                  L  REH
Sbjct  453  AGKSCFH--------SGKSLLSNVFLIINSLITYLTRLGDGRTNQIISLITLQILLAREH  504

Query  309  NRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG--YFLQLKFDPELLF  366
            NRV   L   +P+  DE LFQ  R I+I E   I   E++  + G     + +  P L  
Sbjct  505  NRVAGALHELNPSASDETLFQEARRIVIAEMQHITYNEFLPIIIGPQQMKRFRLVP-LHQ  563

Query  367  GVQFQYRNR----IAMEFNHLYHW--HPLMPDSFKVGSQEYSYEQ------FLFNTSML-  413
            G    Y       I  EF+   +   H  +   F++  +    ++       +FN S + 
Sbjct  564  GYSHDYNVNVNPAITNEFSGAAYRMGHSSVDGKFQIRQEHGRIDEVVNIPDVMFNPSRMR  623

Query  414  ----VDYGVEALVDAFSRQIAGRIGGG------RNMDHHILHVAVDVIRESREMRLQPFN  463
                 D  +  L     +Q+   I  G      R  +   L +A   I+  R+  L+ +N
Sbjct  624  KREFYDDMLRTLYSQPMQQVDSSISQGLSRFLFRGDNPFGLDLAAINIQRGRDQGLRSYN  683

Query  464  EYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIE  523
            +Y +  G     SF++     E+A +L  +Y   D ++ + G LLEK     + G +  E
Sbjct  684  DYLELMGAPKLHSFEQF--PIEIAQKLSRVYRTPDDIDLWVGGLLEKAVEGGVVGVTFAE  741

Query  524  IGAPFSLKGLLGNPICSPEYW-------KPSTFGGEVGFNIVKTATLKKLVCLNT  571
            I A    +   G+      Y+        P  F   +    ++  TL +L+C N+
Sbjct  742  IIADQFARFKQGD-----RYYYEYDNGINPGAF-NPLQLQEIRKVTLARLLCDNS  790


>sp|Q3UQ28.1|PXDN_MOUSE  RecName: Full=Peroxidasin homolog; Flags: Precursor
Length=1475

 GENE ID: 69675 Pxdn | peroxidasin homolog (Drosophila) [Mus musculus]
(Over 10 PubMed links)

 Score = 60.8 bits (146),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 76/336 (22%), Positives = 143/336 (42%), Gaps = 48/336 (14%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
             GL    TLW REHNR+   L   +P W  + ++  TR I+  E   I    ++ ++ G  
Sbjct  980   GLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHETRKIVGAEIQHITYRHWLPKILGE-  1038

Query  356   LQLK-------FDPELLFGVQFQYRNRIAMEFNHLYHWHPLM---PDSFK-VGSQEYSYE  404
             + +K       +DP +  G+ F      A  F H    +PL+    ++F+ +        
Sbjct  1039  VGMKMLGEYRGYDPSVNAGI-FNAFATAAFRFGHTL-INPLLYRLDENFEPIPQGHVPLH  1096

Query  405   QFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHVAV  448
             +  F+   +V+   E  +D   R + G  G  R               +M H + L +A 
Sbjct  1097  KAFFSPFRIVN---EGGIDPLLRGLFGVAGKMRIPSQLLNTELTERLFSMAHTVALDLAA  1153

Query  449   DVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKE---MAAELEELYGDIDALEFYPG  505
               I+  R+  + P+++YR    +    +F++L  E +   +  +L+ LYG    ++ +P 
Sbjct  1154  INIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIKSPVIREKLQRLYGSTLNIDLFPA  1213

Query  506   LLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKK  565
             L++E   P S  G +++ + +    +   G+ +    Y  P  F        +K  +L +
Sbjct  1214  LMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLW---YENPGVF-SPAQLTQLKQTSLAR  1269

Query  566   LVCLNTKTCPYVS---FRVPD-----ASQDDGPAVE  593
             ++C N+     V    FRV +     +S +D P V+
Sbjct  1270  ILCDNSDNITRVQQDVFRVAEFPHGYSSCEDIPRVD  1305


>sp|A1KZ92.2|PXDNL_HUMAN  RecName: Full=Peroxidasin-like protein; AltName: Full=Vascular 
peroxidase 2; AltName: Full=Cardiac peroxidase; Flags: Precursor
Length=1463

 GENE ID: 137902 PXDNL | peroxidasin homolog (Drosophila)-like [Homo sapiens]
(10 or fewer PubMed links)

 Score = 56.6 bits (135),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 74/340 (21%), Positives = 137/340 (40%), Gaps = 61/340 (17%)

Query  227   VDLGHIYGDNLERQYQLRLFKDGKLKYQVLD-GEMYPPSVEEAPVLMHYPRGIPPQSQMA  285
             +D  ++YG + ER+ Q    +D  +   +L  G  +PPS +    L+ +  G PP     
Sbjct  894   IDGSNVYGSS-ERESQA--LRDPSVPRGLLKTGFPWPPSGKP---LLPFSTG-PPTECAR  946

Query  286   VGQEVFGLLPG---------LMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI  336
               QE    L G         L    TLW REHNRV   L A +P W    ++Q  R I+ 
Sbjct  947   QEQESPCFLAGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVG  1006

Query  337   GETIKIVIEEYV---------QQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNH-----  382
              E   I    ++         + L GY     ++P +  G+   +    A  F H     
Sbjct  1007  AELQHITYSHWLPKVLGDPGTRMLRGY---RGYNPNVNAGIINSFAT-AAFRFGHTLINP  1062

Query  383   -LYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDH  441
              LY  +  + +   +      + + LF+ S ++    E  +D   R + G     R   +
Sbjct  1063  ILYRLNATLGE---ISEGHLPFHKALFSPSRIIK---EGGIDPVLRGLFGVAAKWRAPSY  1116

Query  442   HI----------------LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VG  482
              +                +  A  +I+  R+  + P+ ++R    +    +F++L   + 
Sbjct  1117  LLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIK  1176

Query  483   EKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI  522
             + E+  +L +LYG    ++ +P L++E   P +  G +++
Sbjct  1177  DSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLM  1216


>sp|Q9VZZ4.1|PXDN_DROME  RecName: Full=Peroxidasin; Flags: Precursor
Length=1527

 Score = 56.2 bits (134),  Expect = 5e-07, Method: Compositional matrix adjust.
 Identities = 56/240 (23%), Positives = 113/240 (47%), Gaps = 28/240 (11%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQL---S  352
             GL+   T+W+REHNR+   LK  +  W  + L+Q  R I+  +   I  ++++  +   S
Sbjct  1018  GLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGES  1077

Query  353   GYFLQLKF---DPELLFGVQFQYRNRIAMEFNHLYHWHPLM---PDSFKVGSQEYS--YE  404
             G  +  ++   +P+L   +  ++    A+ F H    +P++    ++F+   Q +   ++
Sbjct  1078  GMEMMGEYQGYNPQLNPSIANEFAT-AALRFGHTI-INPILHRLNETFQPIPQGHLLLHK  1135

Query  405   QFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILH--------VAVDV----IR  452
              F     +  + GV+ L+  F    A      +N++  +          VA+D+    I+
Sbjct  1136  AFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQ  1195

Query  453   ESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGLLLE  509
               R+  +  +N YRK   +     F++L GE    E+  +++ELYG  D ++ + G +LE
Sbjct  1196  RGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILE  1255


>sp|Q9MZF4.1|DUOX1_CANFA  RecName: Full=Dual oxidase 1; AltName: Full=NADPH thyroid oxidase 
1; Short=Thyroid oxidase 1; Flags: Precursor
Length=1551

 GENE ID: 403720 DUOX1 | dual oxidase 1 [Canis lupus familiaris]
(10 or fewer PubMed links)

 Score = 55.8 bits (133),  Expect = 6e-07, Method: Compositional matrix adjust.
 Identities = 74/301 (24%), Positives = 115/301 (38%), Gaps = 51/301 (16%)

Query  219  FTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQ---VLDGEMYPPSVE-EAPVLMHY  274
             T A+   +D   IYG +      LR F  G+L             PP +   AP     
Sbjct  165  LTNAVTGWLDGSAIYGSSHSWSDALRSFSGGQLASGPDPAFPRNAQPPLLMWSAPDPASG  224

Query  275  PRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLI  334
             RG  P    A G E     P L     LW R HN     L  +HP WGDE+LFQ  R  
Sbjct  225  QRG--PGGLYAFGAERGNRDPFLQALGLLWFRYHNLCAQRLARQHPHWGDEELFQHARKR  282

Query  335  LIGETIKIVIEE----YVQQL----SGY--FLQLKFDPELLFGV-QF--------QYRNR  375
            +I     I + E    ++QQ     +GY  FL     PE L    QF         Y   
Sbjct  283  VIATYQNIALYEWLPSFLQQAPVKYAGYNPFLDPSISPEFLVASEQFFSTMVPPGIYMRN  342

Query  376  IAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGG  435
             +  F  + + +  +  + +V +  +S +    + ++     V+AL+   + QIA R   
Sbjct  343  ASCHFQEVINRNSSISRALRVCNSYWSRK----HPNLRRAEDVDALLLGMASQIAER---  395

Query  436  GRNMDHHILHVAVD----------------VIRESREMRLQPFNEYRKRFGMKPYTSFQE  479
                DH ++   +D                 ++  R++ L  + + R   G+ P T +Q+
Sbjct  396  ---EDHVVVEDVLDFWPGSLKFSRTDHVAGCLQRGRDLGLPSYTKARAALGLPPITRWQD  452

Query  480  L  480
            +
Sbjct  453  I  453


>sp|Q01603.1|PERO_DROME  RecName: Full=Peroxidase; Short=DmPO; AltName: Full=Chorion peroxidase; 
Flags: Precursor
Length=690

 Score = 55.5 bits (132),  Expect = 8e-07, Method: Compositional matrix adjust.
 Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 18/130 (13%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAV  286
            +DL  +YG+++++   +R F+ G++  +  +G  + P            R +        
Sbjct  270  LDLSLVYGNSIQQNSDIREFQGGRMIVEERNGAKWLP----------LSRNVTGDCDAVD  319

Query  287  GQEV--------FGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGE  338
              EV            PGL +  T+ LREHNR+ D L A +P + D  LFQ  R I I +
Sbjct  320  ASEVCYRSGDVRVNQNPGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQ  379

Query  339  TIKIVIEEYV  348
              +I   E++
Sbjct  380  YQQISYYEWL  389


>sp|P35419.1|PERT_MOUSE  RecName: Full=Thyroid peroxidase; Short=TPO; Flags: Precursor
Length=914

 GENE ID: 22018 Tpo | thyroid peroxidase [Mus musculus] (Over 10 PubMed links)

 Score = 54.7 bits (130),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 73/337 (21%), Positives = 136/337 (40%), Gaps = 38/337 (11%)

Query  294  LPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG  353
            +P L    TLWLREHNR+    KA +  W     +Q  R ++      I + +Y+ ++ G
Sbjct  388  VPALAAVHTLWLREHNRLASAFKAINKHWSANTAYQEARKVVGALHQIITMRDYIPKILG  447

Query  354  --YFLQL-----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYS----  402
               F Q       ++P +   V   + +  A  F H    HPL+        QE++    
Sbjct  448  PDAFRQYVGPYEGYNPTVNPTVSNIF-STAAFRFGHATV-HPLV-RRLNTDFQEHTELPR  504

Query  403  ---YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI------------LHVA  447
                + F     ++ + G++ +V     + A     G+ M+  +            L +A
Sbjct  505  LQLRDVFFRPWRLIQEGGLDPIVRGLLARAAKLQVQGQLMNEELTERLFVLSNVGTLDLA  564

Query  448  VDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYP  504
               ++  R+  L  +NE+R+  G+    +  EL   +  + M  ++ +LY   D ++ + 
Sbjct  565  SLNLQRGRDHGLPDYNEWREFCGLSRLETPAELNKAIANRSMVNKIMDLYKHADNIDVWL  624

Query  505  GLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLK  564
            G L EK  P +  G     I     +K L         +W+ +    +     ++  +L 
Sbjct  625  GGLAEKFLPGARTGPLFACIIGK-QMKALRDG---DRFWWENTNVFTDAQRQELEKHSLP  680

Query  565  KLVCLNT--KTCPYVSFRVPDASQDDGPAVERPSTEL  599
            +++C NT     P  +FR+    QD     + PS +L
Sbjct  681  RVICDNTGLTRVPVDAFRIGKFPQDFESCEDIPSMDL  717


>sp|P11247.1|PERM_MOUSE  RecName: Full=Myeloperoxidase; Short=MPO; Contains: RecName: 
Full=Myeloperoxidase light chain; Contains: RecName: Full=Myeloperoxidase 
heavy chain; Flags: Precursor
Length=718

 GENE ID: 17523 Mpo | myeloperoxidase [Mus musculus] (Over 100 PubMed links)

 Score = 54.3 bits (129),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 73/315 (23%), Positives = 141/315 (44%), Gaps = 53/315 (16%)

Query  294  LPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVI-EEYVQQLS  352
            +P L    TL++REHNR+   LK  +P W  E+L+Q  R I +G  ++I+   +Y+  + 
Sbjct  383  MPELTSMHTLFVREHNRLATQLKRLNPRWNGEKLYQEARKI-VGAMVQIITYRDYLPLVL  441

Query  353  GYFLQLKFDPELLFGVQFQYRN-------RIAMEFNHLYHW-HPLM-PDSFKVGSQEYSY  403
            G     K+ P        QYR+       RIA  F + + + H L+ P  F++ +Q    
Sbjct  442  GPAAMKKYLP--------QYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLNNQYRPT  493

Query  404  ---------EQFLFNTSMLVDYGVEALVDA-------FSRQIAGRIGGGR-NMDHHILHV  446
                     + F  +  ++++ G++ ++          +RQ    +   R  +   ++ +
Sbjct  494  AANPRVPLSKVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIVVDEIRERLFEQVMRI  553

Query  447  AVDV----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDA  499
             +D+    ++ SR+  L  +N +R+  G+   ++  EL   +   E+A +L   YG  + 
Sbjct  554  GLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNN  613

Query  500  LEFYPGLLLEKCHPNSIFGESM-IEIGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFN  556
            ++ + G + E   PN   G+ +   IG  F  K   G+      +W   P  F  +    
Sbjct  614  IDIWMGGVSEPLEPNGRVGQLLACLIGTQFR-KLRDGD-----RFWWENPGVFSKQ-QRQ  666

Query  557  IVKTATLKKLVCLNT  571
             + + +L +L+C NT
Sbjct  667  ALASISLPRLICDNT  681


>sp|P14650.1|PERT_RAT  RecName: Full=Thyroid peroxidase; Short=TPO; Flags: Precursor
Length=914

 GENE ID: 54314 Tpo | thyroid peroxidase [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 53.9 bits (128),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 90/413 (21%), Positives = 159/413 (38%), Gaps = 51/413 (12%)

Query  227  VDLGHIYGDNLERQYQLRLFKD--GKLKYQVL---DGEMYPPSVEEAPVLMHYPRGIPPQ  281
            +D   +YG +   + QLR +    G L+   L    G  Y P    A      P    P 
Sbjct  316  LDASTVYGSSPGVEKQLRNWSSSAGLLRVNTLHLDSGRAYLPFASAACA----PEPGAPH  371

Query  282  SQMA----VGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG  337
            +        G      +P L    TLWLREHNR+    KA +  W     +Q  R ++  
Sbjct  372  ANRTPCFLAGDGRASEVPALAAVHTLWLREHNRLATAFKAINTHWSANTAYQEARKVVGA  431

Query  338  ETIKIVIEEYVQQLSG--YFLQL-----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
                I + +Y+ ++ G   F Q       ++P +   V   + +  A  F H    HPL+
Sbjct  432  LHQIITMRDYIPKILGPDAFRQYVGPYEGYNPTVNPTVSNVF-STAAFRFGHATV-HPLV  489

Query  391  PDSFKVGSQEYS-------YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
                    Q+++       ++ F     ++ + G++ +V     + A      + M+  +
Sbjct  490  -RRLNTDFQDHTELPRLQLHDVFFRPWRLIQEGGLDPIVRGLLARPAKLQVQEQLMNEEL  548

Query  444  ------------LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAA  488
                        L +A   ++  R+  L  +NE+R+  G+    +  EL   +  + M  
Sbjct  549  TERLFVLSNVGTLDLASLNLQRGRDHGLPGYNEWREFCGLSRLDTGAELNKAIANRSMVN  608

Query  489  ELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPST  548
            ++ ELY   D ++ + G L EK  P +  G     I     +K L         +W+ S 
Sbjct  609  KIMELYKHADNIDVWLGGLAEKFLPGARTGPLFACIIGK-QMKALRDG---DRFWWENSH  664

Query  549  FGGEVGFNIVKTATLKKLVCLNT--KTCPYVSFRVPDASQDDGPAVERPSTEL  599
               +     ++  +L +++C NT     P  +FR+    QD     E PS +L
Sbjct  665  VFTDAQRQELEKHSLPRVICDNTGLTRVPVDAFRIGKFPQDFESCEEIPSMDL  717


>sp|Q8HZK2.2|DUOX2_PIG  RecName: Full=Dual oxidase 2; AltName: Full=NADH/NADPH thyroid 
oxidase p138-tox; Flags: Precursor
Length=1545

 GENE ID: 397060 DUOX2 | dual oxidase 2 [Sus scrofa] (10 or fewer PubMed links)

 Score = 53.5 bits (127),  Expect = 4e-06, Method: Compositional matrix adjust.
 Identities = 42/129 (32%), Positives = 54/129 (41%), Gaps = 12/129 (9%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYP-------RGIP  279
            +D   IYG +     +LR F  G+L       +   P   + P+ M  P       RG  
Sbjct  179  LDGSAIYGSSHSWSDELRSFSGGQLAS---GPDPAFPRQAQDPLFMWTPPDPATGQRG--  233

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
            PQ   A G E     P L     LW R HN     L  EHP WGDE+LFQ  R  +I   
Sbjct  234  PQGLYAFGAEQGNREPFLQALGLLWFRYHNLCAQKLAREHPLWGDEELFQHARKRVIATY  293

Query  340  IKIVIEEYV  348
              I + E++
Sbjct  294  QSITMYEWL  302


>sp|Q8CIY2.1|DUOX1_RAT  RecName: Full=Dual oxidase 1; Flags: Precursor
Length=1551

 GENE ID: 266807 Duox1 | dual oxidase 1 [Rattus norvegicus]
(10 or fewer PubMed links)

 Score = 53.1 bits (126),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 67/293 (22%), Positives = 111/293 (37%), Gaps = 51/293 (17%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIP----PQS  282
            +D   IYG +      LR F  G+L         +P + + + ++   P        PQ 
Sbjct  173  LDGSAIYGSSHSWSDTLRSFSGGQLASG--PDPAFPRNSQNSLLMWMAPDPATGQGGPQG  230

Query  283  QMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKI  342
              A G +     P L     LW R HN     L  EHP WGDE+LFQ  R  +I     I
Sbjct  231  LYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNI  290

Query  343  VIEEYV--------QQLSGY--FLQLKFDPELLFGV-QF--------QYRNRIAMEFNHL  383
             + E++         +  GY  FL     PE +    QF         Y    +  F  +
Sbjct  291  AMYEWLPSFLKQTPPEYPGYHPFLDPSISPEFVVASEQFLSTMVPPGVYMRNASCHFQGI  350

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
             + +  +  + +V +  +S E    N  +     V+AL+   + QIA R       DH +
Sbjct  351  ANRNSSVSGALRVCNSYWSRE----NPKLQRAEDVDALLLGMASQIAER------EDHLV  400

Query  444  LHVAVD----------------VIRESREMRLQPFNEYRKRFGMKPYTSFQEL  480
            +    D                 ++  R++ L  + + R+  G+ P + +Q++
Sbjct  401  VEDVQDFWPGPLKFSRTDYLASCLQRGRDLGLPSYTKAREALGLPPVSHWQDI  453


>sp|P22079.2|PERL_HUMAN  RecName: Full=Lactoperoxidase; Short=LPO; AltName: Full=Salivary 
peroxidase; Short=SPO; Flags: Precursor
Length=712

 GENE ID: 4025 LPO | lactoperoxidase [Homo sapiens] (Over 10 PubMed links)

 Score = 52.8 bits (125),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 76/306 (24%), Positives = 121/306 (39%), Gaps = 49/306 (16%)

Query  302  TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD  361
            TL+LREHNR+   LK  +P W  E+L+Q  R IL      I   +Y+  L G  +Q    
Sbjct  384  TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP  443

Query  362  PELLFGVQFQYRNRIAMEFNHLYHW-HPLMPDS-FKVGSQ--------EYSYEQFLFNT-  410
            P    G       RI+  F   + + H  +P S F++           E       FNT 
Sbjct  444  P--YQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW  501

Query  411  SMLVDYGVEALVDAF----------SRQIAGRIGGGRNMDHHILH---VAVDVIRESREM  457
             M+ D G++ LV             ++ + G +        H +H   +A    +  R+ 
Sbjct  502  RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH  561

Query  458  RLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPN  514
                +N +R    +    + +EL   +  K +A +L  LYG  D ++ + G +       
Sbjct  562  GQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAI-------  614

Query  515  SIFGESMIEIG--APFSLKGLLGNPICS----PEYW--KPSTFGGEVGFNIVKTATLKKL  566
                E ++E G   P  L  LLG           +W   P  F  E   ++ K  +  +L
Sbjct  615  ---AEPLVERGRVGPL-LACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKM-SFSRL  669

Query  567  VCLNTK  572
            VC NT+
Sbjct  670  VCDNTR  675


>sp|A4IGL7.1|PXDN_XENTR  RecName: Full=Peroxidasin; Flags: Precursor
Length=1457

 GENE ID: 493201 pxdn | peroxidasin homolog [Xenopus (Silurana) tropicalis]
(10 or fewer PubMed links)

 Score = 52.4 bits (124),  Expect = 8e-06, Method: Compositional matrix adjust.
 Identities = 66/322 (20%), Positives = 131/322 (40%), Gaps = 45/322 (13%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
             GL    TLW REHNR+   L   +P W  + ++  TR I+  +   I    ++ ++ G  
Sbjct  972   GLTSMHTLWFREHNRIATELLRLNPHWDGDTIYHETRKIVGAQMQHITYSHWLPKIFGDV  1031

Query  356   -LQL-----KFDPELLFGVQFQYRNRIAMEFNHLYHWHPL---MPDSFK-VGSQEYSYEQ  405
              +++      +DP +  G+  ++    A  F H    +P+   + + F+ +        +
Sbjct  1032  GMKMLGEYKSYDPNVNAGILNEFAT-AAFRFGHTL-INPILYRLDEKFEPIPQGHVPLHR  1089

Query  406   FLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHVAVD  449
               F+   +V+   E  +D   R + G     R               +M H + L +A  
Sbjct  1090  AFFSPFRIVN---EGGIDPLLRGLIGVAAKMRVTSQLLNTELTEKLFSMAHAVALDLAAL  1146

Query  450   VIRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGL  506
              ++  R+  + P++++R    +    +F +L  E    ++  +L+ LYG    ++ +P L
Sbjct  1147  NVQRGRDHGIPPYHDFRVFCNLSTVQTFDDLRNEIKNPDVREKLKRLYGSPLNIDLFPAL  1206

Query  507   LLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFNIVKTATLK  564
             ++E   P S  G +++ +     L     N      +W   P  F        +K  +L 
Sbjct  1207  MVEDLIPGSRLGPTLMCL-----LTTQFRNIRDGDRFWYENPGVFTA-AQLTQIKQTSLA  1260

Query  565   KLVCLNTKTCPYVS---FRVPD  583
             +++C N      V    FRV +
Sbjct  1261  RVLCDNGDNITKVQHDLFRVAE  1282
Select All Get selected sequences
sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase...

Distribution of 35 Blast Hits on the Query Sequence [?]
