Your search is limited to records matching entrez query: Chordata [ORGN] NOT Mammalia [ORGN].
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Alignment Text XML ASN.1 Hit Table(text) Hit Table(csv)	Search Strategies ASN.1	Bioseq ASN.1	PSSM Text	PssmWithParameters ASN.1	[?]
sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase...

Query ID: lcl|4640
Description: sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase 1 OS=Homo sapiens GN=PTGS1 PE=1 SV=1
Molecule type: amino acid
Query Length: 599
Database Name: nr
Description: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects See details
Program: BLASTP 2.2.19+ Citation
Other reports: Search Summary [Distance tree of results]
Search Parameters
Program	blastp
Word size	3
Expect value	10
Hitlist size	100
Gapcosts	11,1
Matrix	BLOSUM62
Threshold	11
Composition-based stats	2
Low Complexity Filter	Yes
Filter string	L;
Genetic Code	1
Window Size	40
Database
Posted date	Feb 8, 2009 5:55 PM
Number of letters	2,699,925,127
Number of sequences	7,833,073
Entrez query	Chordata [ORGN] NOT Mammalia [ORGN]
Karlin-Altschul statistics
Params	Ungapped	Gapped
Lambda	0.321898	0.267
K	0.140185	0.041
H	0.44714	0.14
Results Statistics
Length adjustment	120
Effective length of query	479
Effective length of database	83480912
Effective search space	39987356848
Effective search space used	39987356848
Alignments Select All Get selected sequences

>ref|XP_425326.2|  PREDICTED: similar to Prostaglandin G/H synthase 1 precursor 
(Cyclooxygenase-1) (COX-1) (Prostaglandin-endoperoxide synthase 
1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) 
(PHS 1) [Gallus gallus]
Length=649

 GENE ID: 427752 PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin
G/H synthase and cyclooxygenase) [Gallus gallus]

 Score =  894 bits (2310),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 448/580 (77%), Positives = 507/580 (87%), Gaps = 4/580 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
             D  + + VNPCCYYPCQHQG+CVR GL+ Y+CDCTRTGY G NCT P LWT LR+ L+P
Sbjct  70   GDLSSLSAVNPCCYYPCQHQGVCVRVGLEGYECDCTRTGYFGANCTSPELWTRLRDLLKP  129

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SP+F HF+LTH RWFW+ +N+TFIR+ LMRLVLTVR+NLIPSPPT+NS + YISWE+++N
Sbjct  130  SPTFYHFVLTHFRWFWDIINSTFIRDTLMRLVLTVRANLIPSPPTFNSQYGYISWEAYAN  189

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            VSYYTRILP VP++CPTPMGTKGK+QLPDAQLLA+RFLLR KF  DP+GTNLMFAFFAQH
Sbjct  190  VSYYTRILPPVPEECPTPMGTKGKQQLPDAQLLAQRFLLRHKFEADPRGTNLMFAFFAQH  249

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKTSGKMG GFTKALGHGVDLGH+YGDNL+RQ+QLRLF+DGKLK+QV++GE+YPP
Sbjct  250  FTHQFFKTSGKMGRGFTKALGHGVDLGHLYGDNLQRQHQLRLFQDGKLKFQVVNGEVYPP  309

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SV E PV M YP  IP + Q+A+GQEVFGLLPGL +YATLWLREHNRVCD+LK EHPTWG
Sbjct  310  SVTEVPVHMVYPPAIPKEKQLAMGQEVFGLLPGLCMYATLWLREHNRVCDILKQEHPTWG  369

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQT RLILIGETIKIVIE+YVQ LSGYFL LKFDPELLF  QFQYRNRIA+EFN L
Sbjct  370  DEQLFQTARLILIGETIKIVIEDYVQHLSGYFLNLKFDPELLFEQQFQYRNRIAVEFNQL  429

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWH LMPDSF +  QEYSYEQFL+NTSML+DYGVEAL ++FS Q AGRIGGG+N++ ++
Sbjct  430  YHWHALMPDSFTIQGQEYSYEQFLYNTSMLMDYGVEALAESFSMQTAGRIGGGQNINANV  489

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
            L VAV VI ESR++RLQPFNEYRKRFG+KPYTSFQEL GE++ AAELEELYGDIDALEFY
Sbjct  490  LGVAVGVIEESRQLRLQPFNEYRKRFGLKPYTSFQELTGEEDKAAELEELYGDIDALEFY  549

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEK  PN IFGESM+EIGAPFSLKGLLGNPICSPEYWKPSTFGG  GF IVKTA+L
Sbjct  550  PGLLLEKPQPNGIFGESMVEIGAPFSLKGLLGNPICSPEYWKPSTFGGATGFEIVKTASL  609

Query  564  KKLVCLNTKTCPYVSFRVPDASQ----DDGPAVERPSTEL  599
            +KLVCLN K CPYV+F VPDA+     D G A    STEL
Sbjct  610  EKLVCLNVKKCPYVAFHVPDAAAAGETDSGHAGGASSTEL  649


>gb|AAI70301.1|  Cyclooxygenase 1 [Xenopus laevis]
 gb|AAI70299.1|  Cyclooxygenase 1 [Xenopus laevis]
Length=587

 GENE ID: 100037245 cox1 | cyclooxygenase 1 [Xenopus laevis]

 Score =  861 bits (2224),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 416/555 (74%), Positives = 482/555 (86%), Gaps = 0/555 (0%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTH  89
            T VNPCCYYPCQH+G+CVRF ++ YQCDCTRTGY G NCTIP  WT  R  +RPSP+F H
Sbjct  23   TKVNPCCYYPCQHKGVCVRFEMEEYQCDCTRTGYYGTNCTIPEWWTKFRELIRPSPAFYH  82

Query  90   FLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTR  149
            ++LT  +WFW+ +N+TFIR+ ++RLVLTVRSNLIPSPPTYNS + YISWE++SNVSY+TR
Sbjct  83   YILTRFKWFWDIINSTFIRDFIVRLVLTVRSNLIPSPPTYNSEYGYISWEAYSNVSYFTR  142

Query  150  ILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqff  209
            +LP VP DCPTPMGTKGKK+LPDA  L   FL R KFIPDPQGTNL+FAFFAQHFTHQFF
Sbjct  143  VLPPVPHDCPTPMGTKGKKELPDATFLVETFLKREKFIPDPQGTNLLFAFFAQHFTHQFF  202

Query  210  ktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAP  269
            KT G+MG GF K  GHGVDL HIYGD+LERQ+ LRLFKDGKLKYQ+++GE YPP+V EAP
Sbjct  203  KTYGRMGRGFIKGFGHGVDLSHIYGDSLERQHILRLFKDGKLKYQIINGETYPPTVVEAP  262

Query  270  VLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQ  329
            V M YP  +P + Q AVGQEVFGLLPGLM+YATLWLREHNRVCD+LK EHPTW DEQLFQ
Sbjct  263  VHMIYPENVPKEKQFAVGQEVFGLLPGLMMYATLWLREHNRVCDVLKKEHPTWDDEQLFQ  322

Query  330  TTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPL  389
            TTRLILIGETIKIVIE+YVQ LSGY+L+LKFDPELLFGVQFQYRNRIA+EFN LYHWHPL
Sbjct  323  TTRLILIGETIKIVIEDYVQHLSGYYLKLKFDPELLFGVQFQYRNRIAVEFNQLYHWHPL  382

Query  390  MPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVD  449
            MP+ FK+   E+ Y  F++NTS+++DYGVEALV++F++QIAG+IGGG+N    +L VA  
Sbjct  383  MPEKFKIIEDEFGYSSFIYNTSIILDYGVEALVESFTKQIAGKIGGGKNHPPSLLKVAAG  442

Query  450  VIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLE  509
            VI ESR +RLQPFNEYRKRFG+K Y SF++L GE++MAA+LEE YGDIDALEFY GLLLE
Sbjct  443  VIEESRNLRLQPFNEYRKRFGLKAYKSFRDLTGEEKMAAQLEEFYGDIDALEFYVGLLLE  502

Query  510  KCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCL  569
            K +PNSIFGESM+EIGAPFSLKGLLGNPICSPEYWKPSTFGGE GFNIVKTA+++KLVCL
Sbjct  503  KPNPNSIFGESMVEIGAPFSLKGLLGNPICSPEYWKPSTFGGETGFNIVKTASIQKLVCL  562

Query  570  NTKTCPYVSFRVPDA  584
            N KTCP+V+F VPD 
Sbjct  563  NVKTCPFVAFHVPDV  577


>ref|NP_001091389.1|  cyclooxygenase 1 [Xenopus laevis]
 dbj|BAF36493.1|  cyclooxygenase 1 [Xenopus laevis]
Length=587

 GENE ID: 100037245 cox1 | cyclooxygenase 1 [Xenopus laevis]

 Score =  857 bits (2214),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 415/555 (74%), Positives = 480/555 (86%), Gaps = 0/555 (0%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTH  89
            T VNPCCYYPCQH+G+CVRF ++ YQCDCTRTGY G NCTIP  WT  R  +RPSP+F H
Sbjct  23   TKVNPCCYYPCQHKGVCVRFEMEEYQCDCTRTGYYGTNCTIPEWWTKFRELIRPSPAFYH  82

Query  90   FLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTR  149
            ++LT  +WFW+ +N+TFIR+ ++RLVLTVRSNLIPSPPTYNS + YISWE++SNVSY+TR
Sbjct  83   YILTRFKWFWDIINSTFIRDFIVRLVLTVRSNLIPSPPTYNSEYGYISWEAYSNVSYFTR  142

Query  150  ILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqff  209
            +LP VP DCPTPMGTKGKK+LPDA  L   FL R KFIPDPQGTNL+FAFFAQHFTHQFF
Sbjct  143  VLPPVPHDCPTPMGTKGKKELPDATFLVETFLKREKFIPDPQGTNLLFAFFAQHFTHQFF  202

Query  210  ktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAP  269
            KT G+MG GF K  GHGVDL HIYGD+LERQ  LRLFKDGKLKYQ+++GE YPP+V EAP
Sbjct  203  KTYGRMGRGFIKGFGHGVDLSHIYGDSLERQQILRLFKDGKLKYQIINGETYPPTVVEAP  262

Query  270  VLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQ  329
            V M YP  +P + Q AVGQEVFGLLPGLM+YATLWLREHNRVCD+LK EHPTW DEQLFQ
Sbjct  263  VHMIYPENVPKEKQFAVGQEVFGLLPGLMMYATLWLREHNRVCDVLKKEHPTWDDEQLFQ  322

Query  330  TTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPL  389
            TTRLILIGETIKIVIE+YVQ LSGY+L+LKFDPELLFGVQFQYRNRIA+EFN LYHWHPL
Sbjct  323  TTRLILIGETIKIVIEDYVQHLSGYYLKLKFDPELLFGVQFQYRNRIAVEFNQLYHWHPL  382

Query  390  MPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVD  449
            MP+ FK+   E+ Y  F++NTS+++DYGVEALV++F++QIAG+IGGG+N    +L VA  
Sbjct  383  MPEKFKIIEDEFGYSSFIYNTSIILDYGVEALVESFTKQIAGKIGGGKNHPPSLLKVAAG  442

Query  450  VIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLE  509
            VI ESR +RLQPFNEYRKRFG+K Y SF++L GE++MAA+LEE YGDIDALEFY GLLLE
Sbjct  443  VIEESRNLRLQPFNEYRKRFGLKAYKSFRDLTGEEKMAAQLEEFYGDIDALEFYVGLLLE  502

Query  510  KCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCL  569
            K +PNSIFGESM+EIGAPF LKGLLGNPICSPEYWKPSTFGGE GFNIVKTA+++KLVCL
Sbjct  503  KPNPNSIFGESMVEIGAPFPLKGLLGNPICSPEYWKPSTFGGETGFNIVKTASIQKLVCL  562

Query  570  NTKTCPYVSFRVPDA  584
            N KTCP+V+F VPD 
Sbjct  563  NVKTCPFVAFHVPDV  577


>gb|ACH73265.1|  cyclooxygenase-1b [Fundulus heteroclitus]
Length=598

 Score =  813 bits (2101),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 399/569 (70%), Positives = 471/569 (82%), Gaps = 3/569 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
             D    + VNPCCY PC+H  +CVR+G D+Y+CDCT TGY G NC+IP LWT +R  L+P
Sbjct  23   GDEVTTSTVNPCCYLPCKHWSVCVRYGEDKYECDCTHTGYYGENCSIPELWTRVRQFLKP  82

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SP   H++LTH  W W+ +N TF+R +LMRLV+T RSNLIPSPPT+NS ++Y+SWES+ N
Sbjct  83   SPDVVHYILTHFHWLWDIINNTFLRNVLMRLVITARSNLIPSPPTFNSKYNYLSWESYYN  142

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            +SYYTRILP VP+DCPTP+G KG+  LPD Q+L  R L RR F PDPQG+N+MFAFFAQH
Sbjct  143  LSYYTRILPPVPEDCPTPLGVKGRNGLPDPQVLFERLLKRRTFRPDPQGSNIMFAFFAQH  202

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKT  +MG GFTKAL HGVD GHIYGD+LERQ+ LRLF+DGKLKYQ++DGE+YPP
Sbjct  203  FTHQFFKTYNRMGLGFTKALSHGVDAGHIYGDSLERQHLLRLFRDGKLKYQLIDGEVYPP  262

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            SV +APV M YP GIP + QMA+GQEVFGLLPGL LYATLWLREHNRVCD+LKAEHPTW 
Sbjct  263  SVTDAPVRMSYPPGIPVEKQMAIGQEVFGLLPGLSLYATLWLREHNRVCDILKAEHPTWD  322

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            DEQLFQTTRLI+IGETI+IVIEEYVQ LSGY LQLKFDP LLF   FQY NRIA+EF+ L
Sbjct  323  DEQLFQTTRLIIIGETIRIVIEEYVQHLSGYLLQLKFDPTLLFNSNFQYGNRIALEFSQL  382

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPDSF +   E SY QFLFNTS+L  YGVE LVDAFSRQ AG+IGGG N++  I
Sbjct  383  YHWHPLMPDSFHISGDELSYSQFLFNTSVLTHYGVEKLVDAFSRQAAGQIGGGHNINAVI  442

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
              V V  I ESR++R+QPFNEYRKRF ++PYTSF++    +E+A+ LEELYGDID LEFY
Sbjct  443  TKVIVGTIEESRQLRIQPFNEYRKRFNLEPYTSFRDFTDSEEIASTLEELYGDIDTLEFY  502

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGLLLEK  P +IFGESM+E+GAPFSLKGLLGNPICSP+YWKPSTFGG+VGF+IV +A+L
Sbjct  503  PGLLLEKTRPGAIFGESMVEMGAPFSLKGLLGNPICSPQYWKPSTFGGKVGFDIVNSASL  562

Query  564  KKLVCLNTKTCPYVSFRVP---DASQDDG  589
            KKLVCLN++TCPYV+F VP   +  ++DG
Sbjct  563  KKLVCLNSRTCPYVAFSVPAEEEPGRNDG  591


>dbj|BAF52621.1|  cyclooxygenase-1 [Micropogonias undulatus]
Length=600

 Score =  811 bits (2095),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 397/563 (70%), Positives = 466/563 (82%), Gaps = 0/563 (0%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
             D    + VNPCCY PCQH G+CVR+G D+Y+CDCTRTGY G NCT+P  WT +R  L+P
Sbjct  23   GDEVTSSTVNPCCYLPCQHWGVCVRYGEDKYECDCTRTGYFGENCTVPEFWTRVRQFLKP  82

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SP   H++LTH RW W+ VN T++R++LMRLVLT RS LIPSPPTYNS + Y+SWES+ N
Sbjct  83   SPDVVHYILTHFRWLWDIVNYTYLRDVLMRLVLTARSTLIPSPPTYNSKYSYLSWESYYN  142

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            +SYYTR+LP VPKDCPTP+G KGK  LPD +LL  R L RR F  DPQG+NLMFAFFAQH
Sbjct  143  LSYYTRLLPPVPKDCPTPLGVKGKAGLPDPELLVERLLKRRTFRLDPQGSNLMFAFFAQH  202

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKT  +MG G+TKAL HGVD GHIYGD+L+RQ QLRL KDGKLKYQ++DGE+YPP
Sbjct  203  FTHQFFKTYNRMGLGYTKALAHGVDAGHIYGDSLKRQLQLRLHKDGKLKYQLIDGEIYPP  262

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            S+ +APV M+YP GIPP+ Q A+GQEVFGLLPGL +YATLWLREHNRVCD+LKA HPTW 
Sbjct  263  SIADAPVRMNYPPGIPPEKQFAIGQEVFGLLPGLGMYATLWLREHNRVCDILKAAHPTWD  322

Query  324  DEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            D+QLFQT+RLI+IGETIKIVIEEYVQ LSGY LQLKFDP LLF   FQY NRIA+EF+ L
Sbjct  323  DDQLFQTSRLIIIGETIKIVIEEYVQHLSGYLLQLKFDPTLLFNSNFQYGNRIALEFSQL  382

Query  384  YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHI  443
            YHWHPLMPD F +   E SY QFLFNTS+L  YG++ LVDAFSRQ AG+IGGG N++  +
Sbjct  383  YHWHPLMPDYFIINGDEVSYTQFLFNTSVLTHYGIDKLVDAFSRQNAGQIGGGHNINPVV  442

Query  444  LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFY  503
              VAV  I+ESR++R+QPFNEYRKRF +KPYTSF+E    +E+A ELEE YGDID++EFY
Sbjct  443  TKVAVGAIKESRQLRMQPFNEYRKRFNLKPYTSFREFTDNEEIARELEEFYGDIDSVEFY  502

Query  504  PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATL  563
            PGL+LEK    +IFGESM+E+GAPFSLKGLLGNPICSPEYWKPSTFGG+VGF+IV +ATL
Sbjct  503  PGLMLEKTRSGAIFGESMVEMGAPFSLKGLLGNPICSPEYWKPSTFGGKVGFDIVNSATL  562

Query  564  KKLVCLNTKTCPYVSFRVPDASQ  586
            KKLVCLN+K CPYV+FRVP   Q
Sbjct  563  KKLVCLNSKRCPYVAFRVPTEEQ  585


>gb|ACH73272.1|  cyclooxygenase-1b [Myoxocephalus octodecemspinosus]
Length=600

 Score =  809 bits (2089),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 391/555 (70%), Positives = 467/555 (84%), Gaps = 0/555 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
            VNPCCY+PCQH G+CVR+G D+Y+CDCTRTGY+G NCT+P  W+ +   L+PSP   H++
Sbjct  31   VNPCCYFPCQHWGVCVRYGEDKYECDCTRTGYTGGNCTVPEFWSRVHQFLKPSPEVLHYI  90

Query  92   LTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            LTH  W W+ +N TF+R++LMR+VLTVRSNLIPSPPTYNS +DY+SWES+ N+SYYTRIL
Sbjct  91   LTHFNWLWDIINHTFLRDVLMRMVLTVRSNLIPSPPTYNSKYDYLSWESYYNLSYYTRIL  150

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VPKDCPTP+G KGK  LPD +LL  R L RR F PDPQG+NLMFAFFAQHFTHQFFKT
Sbjct  151  PPVPKDCPTPLGVKGKAGLPDPELLVERLLKRRTFRPDPQGSNLMFAFFAQHFTHQFFKT  210

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              +MG GFTKAL HGVD GH+YGDNL+RQ +LRL KDGKLKYQ++DG++YPPSV +APV 
Sbjct  211  YNRMGVGFTKALAHGVDAGHVYGDNLQRQLKLRLHKDGKLKYQLVDGQIYPPSVVDAPVK  270

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP G+PP++QMA+ QEV+GLLPGL ++ATLWLREHNRVCD+LKAEHPTW DEQLFQT 
Sbjct  271  MSYPPGVPPEAQMAICQEVYGLLPGLGMFATLWLREHNRVCDILKAEHPTWDDEQLFQTA  330

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            R ++IGETIKIVIEEYVQQLSGY LQLKFDP LLF   FQY NRIA+EF+ LYHWHPLMP
Sbjct  331  RFVIIGETIKIVIEEYVQQLSGYLLQLKFDPALLFNSNFQYGNRIALEFSQLYHWHPLMP  390

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            +SF +   E  Y++FLFN ++L  YG+E LV AFSRQ+AG+IGGG N++  +  V+V  I
Sbjct  391  ESFLINGDELPYKRFLFNNTVLTHYGIENLVTAFSRQVAGQIGGGFNINAAVTKVSVLTI  450

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
            +ESR++R+QPFNEYRKRF +KPYTSF+E    +E+A ELEE YGD+DALEFYPGLLLE+ 
Sbjct  451  KESRKLRMQPFNEYRKRFNLKPYTSFREFTDNEEIARELEEFYGDVDALEFYPGLLLERT  510

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
               SIFGESM+E+GAPFSLKGLLGNPICSP YWKPSTFGG+VGF+IV +ATLKKLVCLNT
Sbjct  511  REGSIFGESMVEMGAPFSLKGLLGNPICSPVYWKPSTFGGKVGFDIVNSATLKKLVCLNT  570

Query  572  KTCPYVSFRVPDASQ  586
            +TC YV+FRVP   Q
Sbjct  571  RTCSYVAFRVPTEEQ  585


>gb|AAF14529.1|AF158374_1  prostaglandin endoperoxide synthase-1; cyclooxygenase-1 [Salvelinus 
fontinalis]
Length=598

 Score =  803 bits (2074),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/568 (72%), Positives = 470/568 (82%), Gaps = 2/568 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
            VNPCCYYPCQ+  +CVRFG+DRY+CDCTRTG+ G NCTIP  WT +   L+PSP   H++
Sbjct  33   VNPCCYYPCQNWALCVRFGIDRYECDCTRTGFYGQNCTIPEFWTRIHQQLKPSPDVVHYI  92

Query  92   LTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            LTH  W W  +N TF+R+ LMR+VLTVRSNLIPSPPT+NS + Y+SWES+SNVSYYTRIL
Sbjct  93   LTHFHWLWNLINRTFMRDWLMRMVLTVRSNLIPSPPTFNSKYGYLSWESYSNVSYYTRIL  152

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VP+DCPTPMGTKGK  LPD +L+  +FLLRR+F PDP+GTNLMFAFFAQHFTHQFFKT
Sbjct  153  PPVPEDCPTPMGTKGKSVLPDPKLVVEKFLLRRQFRPDPKGTNLMFAFFAQHFTHQFFKT  212

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
               MG GFT ALGHGVD G++YGDNL RQ  LRL KDGK+KYQV+ GE+YPP+V EAPV 
Sbjct  213  RNSMGLGFTSALGHGVDAGNVYGDNLVRQLNLRLLKDGKMKYQVVKGEVYPPTVAEAPVN  272

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP+G P   +MA+GQEVFGLLPGL +YATLWLREHNRVCD+LKAEHPTWGDEQLFQT 
Sbjct  273  MRYPQGTPVGQRMAIGQEVFGLLPGLTMYATLWLREHNRVCDILKAEHPTWGDEQLFQTA  332

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLI+IGETI+IVIEEYVQ LSGY L LKFDP LLF   FQYRNRIA+EFN LYHWHPLMP
Sbjct  333  RLIVIGETIRIVIEEYVQHLSGYLLDLKFDPVLLFKSTFQYRNRIAVEFNQLYHWHPLMP  392

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            DSF +     SY QF+FNTS++  YGVE LVDAFSRQ AG+IGGGRN+   +  VA  VI
Sbjct  393  DSFHIDGDVVSYSQFIFNTSIVTHYGVEKLVDAFSRQYAGQIGGGRNIHPVVTKVAEGVI  452

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             ESR +RLQPFNEYRKRF +KPYTSF +  GE+EMA ELEELYGDIDALEFYP L+LEK 
Sbjct  453  EESRTLRLQPFNEYRKRFNLKPYTSFSDFTGEEEMARELEELYGDIDALEFYPALMLEKT  512

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             PN+IFGESM+E+GAPFSLKGLLGNPICSPEYWKPSTFGG+ GF+IV +A+L++LVCLNT
Sbjct  513  RPNAIFGESMVEMGAPFSLKGLLGNPICSPEYWKPSTFGGQTGFDIVNSASLERLVCLNT  572

Query  572  KTCPYVSFRVPDASQDDGPAVERPSTEL  599
              CPYV+F VP A Q+  P   + STEL
Sbjct  573  NWCPYVAFNVPPAGQE--PPPRKQSTEL  598


>ref|NP_001117833.1|  cyclooxygenase-1 [Oncorhynchus mykiss]
 emb|CAC10360.1|  cyclooxygenase-1 [Oncorhynchus mykiss]
Length=624

 GENE ID: 100136038 cox-1 | cyclooxygenase-1 [Oncorhynchus mykiss]

 Score =  800 bits (2065),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 407/572 (71%), Positives = 472/572 (82%), Gaps = 2/572 (0%)

Query  28   APTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSF  87
            A T VNPCCYYPCQ+ G+CVRFG+DRY+CDCTRTG+ G NCTIP  WT +   L+PSP  
Sbjct  55   ASTVVNPCCYYPCQNWGVCVRFGIDRYECDCTRTGFYGQNCTIPEFWTRVHQQLKPSPDV  114

Query  88   THFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYY  147
             H++LTH  W W  +N TF+R+ LMR+VLTVRSNLIPSPPT+NS + Y+SWES+SNVSYY
Sbjct  115  VHYILTHFHWLWNLINRTFMRDWLMRVVLTVRSNLIPSPPTFNSKYGYLSWESYSNVSYY  174

Query  148  TRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthq  207
            TRILP VP+DCPTPMGTKGK  LPD +L+  +FLLRR+F  DP+GTNLMFAFFAQHFTHQ
Sbjct  175  TRILPPVPEDCPTPMGTKGKSVLPDPKLVVEKFLLRRQFRRDPRGTNLMFAFFAQHFTHQ  234

Query  208  ffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEE  267
            FFKT   MG GFT+ALGHGVD G++YGDNL RQ  LRL KDGK+KYQV+ GE+YPP+V E
Sbjct  235  FFKTRNSMGLGFTRALGHGVDAGNVYGDNLVRQLNLRLLKDGKMKYQVVKGEVYPPTVAE  294

Query  268  APVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQL  327
            A V M YP+  P   +MA+GQEVFGLLPGL +YATLWLREHNRVCD+LKAEHPTWGDEQL
Sbjct  295  AAVNMRYPQETPVGQRMAIGQEVFGLLPGLTMYATLWLREHNRVCDILKAEHPTWGDEQL  354

Query  328  FQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWH  387
            FQT RLI+IGETI+IVIEEYVQ LSGY L LKFDP LLF   FQYRNRIA+EF  LYHWH
Sbjct  355  FQTARLIVIGETIRIVIEEYVQHLSGYLLDLKFDPVLLFKSTFQYRNRIAVEFKQLYHWH  414

Query  388  PLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVA  447
            PLMPDSF +   E  Y QF+FNTS++  YGVE LVDAFSRQ AG+IGGGRN+   + +VA
Sbjct  415  PLMPDSFHIDGDEVPYSQFIFNTSIVTHYGVEKLVDAFSRQCAGQIGGGRNIHPVVTNVA  474

Query  448  VDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLL  507
              VI ESR +RLQPFNEYRKRF +KPYTSF +  GE+EMA ELEELYGDIDALEFYP ++
Sbjct  475  EGVIEESRTLRLQPFNEYRKRFNLKPYTSFSDFTGEEEMARELEELYGDIDALEFYPAIM  534

Query  508  LEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLV  567
            LEK  PN+IFGESM+E+GAPFSLKGLLGNPICSPEYWKPSTFGG+ GF+IV +A+L++LV
Sbjct  535  LEKTRPNAIFGESMVEMGAPFSLKGLLGNPICSPEYWKPSTFGGQTGFDIVNSASLERLV  594

Query  568  CLNTKTCPYVSFRVPDASQDDGPAVERPSTEL  599
            CLNT  CPYV+F VP A Q++ P   + STEL
Sbjct  595  CLNTNWCPYVAFNVPPAGQEEPP--RKQSTEL  624


>ref|NP_001133846.1|  Prostaglandin G/H synthase 1 [Salmo salar]
 gb|ACI34007.1|  Prostaglandin G/H synthase 1 precursor [Salmo salar]
Length=598

 GENE ID: 100195345 pgh1 | Prostaglandin G/H synthase 1 [Salmo salar]

 Score =  798 bits (2060),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 405/568 (71%), Positives = 471/568 (82%), Gaps = 2/568 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
            VNPCCYYPCQ+ G+CVRFG+DR +CDCTRTG+ G NCTIP  WT +   L+PSP   H++
Sbjct  33   VNPCCYYPCQNWGVCVRFGIDRNECDCTRTGFYGQNCTIPEFWTRIHQQLKPSPDVVHYI  92

Query  92   LTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            LTH  W W  +N TF+R+ LMR+VLTVRSNLIPSPPT+NS + Y+SWES+SNVSYYTRIL
Sbjct  93   LTHFHWLWNLINRTFMRDWLMRVVLTVRSNLIPSPPTFNSKYGYLSWESYSNVSYYTRIL  152

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VP+DCPTPMGTKGK  LPD +L+  +FLLRR+F  DP+GTNLMFAFFAQHFTHQFFKT
Sbjct  153  PPVPEDCPTPMGTKGKSVLPDPKLVVEKFLLRRQFRRDPKGTNLMFAFFAQHFTHQFFKT  212

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
               MG GFT+ALGHGVD G++YGDNLERQ  LRL KDGK+KYQV+ GE+YPP+V EAPV 
Sbjct  213  RNSMGLGFTRALGHGVDAGNVYGDNLERQLSLRLLKDGKMKYQVVKGEVYPPTVAEAPVN  272

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP+G P   +MA+GQEVFGLLPGL +YATLWLREHNRVCD+LKAEHPTWGDEQLFQT 
Sbjct  273  MRYPQGTPVGHRMAIGQEVFGLLPGLTMYATLWLREHNRVCDILKAEHPTWGDEQLFQTA  332

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLI+IGETI+IVIEEYVQ LSGY L LKFDP LLF   FQYRNRIA+EF  LYHWHPLMP
Sbjct  333  RLIVIGETIRIVIEEYVQHLSGYLLDLKFDPVLLFKSTFQYRNRIAVEFKQLYHWHPLMP  392

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            DSF +      Y QF+FNTS++  YGVE LVDAFSRQ AG+IGGGRN+   + +VA  VI
Sbjct  393  DSFHIDGDVVPYSQFMFNTSIVTHYGVEKLVDAFSRQYAGQIGGGRNIHPVVTNVAEGVI  452

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             ESR +RLQPFNEYRKRF +KPYTSF +  GE+E+A ELEELYGDIDALEFYP ++LEK 
Sbjct  453  EESRTLRLQPFNEYRKRFNLKPYTSFSDFTGEEEIARELEELYGDIDALEFYPAIMLEKT  512

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             PN+IFGESM+E+GAPFSLKGLLGNPICSPEYWKPSTFGG+ GF+IV +A+L++LVCLNT
Sbjct  513  RPNAIFGESMVEMGAPFSLKGLLGNPICSPEYWKPSTFGGQTGFDIVNSASLERLVCLNT  572

Query  572  KTCPYVSFRVPDASQDDGPAVERPSTEL  599
              CPYV+F VP A Q++ P   + STEL
Sbjct  573  NWCPYVAFNVPPAGQEEPP--RKQSTEL  598


>ref|NP_705942.1|  prostaglandin-endoperoxide synthase 1 [Danio rerio]
 gb|AAK33030.1|  prostaglandin G/H synthase 1 [Danio rerio]
Length=597

 GENE ID: 246226 ptgs1 | prostaglandin-endoperoxide synthase 1 [Danio rerio]
(Over 10 PubMed links)

 Score =  795 bits (2054),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/558 (70%), Positives = 465/558 (83%), Gaps = 0/558 (0%)

Query  25   DPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPS  84
             P +    NPCCYYPCQ+QGICVR+GL+RY+CDCTRTGY G NCTIP LWT +   L+PS
Sbjct  26   SPTSSNTANPCCYYPCQNQGICVRYGLERYECDCTRTGYYGENCTIPELWTRVYRLLKPS  85

Query  85   PSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNV  144
            P+  H++LTH  W W+ +N +F+R+ LMR VLTVR+NLIPSPPTYNS +DY++WE++SN+
Sbjct  86   PNVVHYILTHFDWLWDLINRSFLRDWLMRKVLTVRANLIPSPPTYNSRYDYLNWEAYSNI  145

Query  145  SYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhf  204
            +YYTRILP VP DCPTPMGTKGK +LPD +LL  +F+LRR F  DPQGTNLMFAFFAQHF
Sbjct  146  TYYTRILPPVPNDCPTPMGTKGKIKLPDPKLLVEKFMLRRNFRLDPQGTNLMFAFFAQHF  205

Query  205  thqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPS  264
            THQFFKT  ++G GFTK LGHGVD GHIYGD+L+RQ +LRL KDGKLKYQVL+G++YPP+
Sbjct  206  THQFFKTHNRVGLGFTKGLGHGVDAGHIYGDSLDRQLELRLHKDGKLKYQVLNGDIYPPT  265

Query  265  VEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGD  324
            V  A V M YP  +PP+ Q+A+GQEVFGLLPGL +YATLWLREHNRVC++LK EHPTWGD
Sbjct  266  VLHAQVKMSYPPSVPPEQQLAIGQEVFGLLPGLGMYATLWLREHNRVCEILKQEHPTWGD  325

Query  325  EQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLY  384
            EQLFQT RLI+IGETI+IVIEEYVQ LSGY L+L FDP LLF  QFQY+NRI++EFN LY
Sbjct  326  EQLFQTARLIIIGETIRIVIEEYVQHLSGYRLKLHFDPTLLFNSQFQYQNRISVEFNQLY  385

Query  385  HWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL  444
            HWHPLMPDSF +      Y +F+FNTS+L  YG+E LV+AFS Q AG+IGGG N+   + 
Sbjct  386  HWHPLMPDSFYIDGDHIQYSKFIFNTSILTHYGLEKLVEAFSIQPAGQIGGGHNIHPVVS  445

Query  445  HVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYP  504
             VA  VI ESRE+RLQPFNEYRKRF +KPYTSF EL GE+EM+ ELEELYG IDA+EFYP
Sbjct  446  GVAERVIVESRELRLQPFNEYRKRFNLKPYTSFAELTGEQEMSKELEELYGHIDAMEFYP  505

Query  505  GLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLK  564
             LLLEK  P ++FGESM+E+GAPFSLKGL+GNPICSP+YWKPSTFGG+ GF+IV +ATLK
Sbjct  506  ALLLEKTRPGAVFGESMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGKTGFDIVNSATLK  565

Query  565  KLVCLNTKTCPYVSFRVP  582
            KLVCLNTK CPYVSF  P
Sbjct  566  KLVCLNTKWCPYVSFHTP  583


>gb|AAI16576.1|  Ptgs1 protein [Danio rerio]
 gb|AAI65770.1|  Ptgs1 protein [Danio rerio]
Length=597

 GENE ID: 246226 ptgs1 | prostaglandin-endoperoxide synthase 1 [Danio rerio]
(Over 10 PubMed links)

 Score =  794 bits (2051),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/558 (70%), Positives = 465/558 (83%), Gaps = 0/558 (0%)

Query  25   DPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPS  84
             P +    NPCCYYPCQ+QGICVR+GL+RY+CDCTRTGY G NCTIP LWT +   L+PS
Sbjct  26   SPTSSNTANPCCYYPCQNQGICVRYGLERYECDCTRTGYYGENCTIPELWTRVYRLLKPS  85

Query  85   PSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNV  144
            P+  H++LTH  W W+ +N +F+R+ LMR VLTVR+NLIPSPPTYNS +DY++WE++SN+
Sbjct  86   PNVVHYILTHFDWLWDLINRSFLRDWLMRKVLTVRANLIPSPPTYNSRYDYLNWEAYSNI  145

Query  145  SYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhf  204
            +YYTRILP VP DCPTPMGTKGK +LPD +LL  +F+LRR F  DPQGTNLMFAFFAQHF
Sbjct  146  TYYTRILPPVPNDCPTPMGTKGKIKLPDPKLLVEKFMLRRNFRLDPQGTNLMFAFFAQHF  205

Query  205  thqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPS  264
            THQFFKT  ++G GFTK LGHGVD GHIYGD+L+RQ +LRL KDGKLKYQVL+G++YPP+
Sbjct  206  THQFFKTHNRVGLGFTKGLGHGVDAGHIYGDSLDRQLELRLHKDGKLKYQVLNGDIYPPT  265

Query  265  VEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGD  324
            V  A V M YP  +PP+ Q+A+GQEVFGLLPGL +YATLWLREHNRVC++LK EHPTWGD
Sbjct  266  VLHAQVKMSYPPSVPPEQQLAIGQEVFGLLPGLGMYATLWLREHNRVCEILKQEHPTWGD  325

Query  325  EQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLY  384
            EQLFQT RLI+IGETI+IVIEEYVQ LSGY L+L FDP LLF  QFQY+NRI++EFN LY
Sbjct  326  EQLFQTARLIIIGETIRIVIEEYVQHLSGYRLKLHFDPTLLFNSQFQYQNRISVEFNQLY  385

Query  385  HWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL  444
            HWHPLMPDSF +      Y +F+FNTS+L  YG+E LV+AFS Q AG+IGGG N+   + 
Sbjct  386  HWHPLMPDSFYIDGDLIQYSKFIFNTSILTHYGLEKLVEAFSIQPAGQIGGGHNIHPVVS  445

Query  445  HVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYP  504
             VA  VI ESRE+RLQPFNEYRKRF +KPYTSF EL GE+EM+ ELEELYG IDA+EFYP
Sbjct  446  GVAERVIVESRELRLQPFNEYRKRFNLKPYTSFAELTGEQEMSNELEELYGHIDAMEFYP  505

Query  505  GLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLK  564
             LLLEK  P ++FGESM+E+GAPFSLKGL+GNPICSP+YWKPSTFGG+ GF+IV +ATLK
Sbjct  506  ALLLEKTRPGAVFGESMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGKTGFDIVNSATLK  565

Query  565  KLVCLNTKTCPYVSFRVP  582
            KLVCLNTK CPYVSF  P
Sbjct  566  KLVCLNTKWCPYVSFHTP  583


>emb|CAF95578.1|  unnamed protein product [Tetraodon nigroviridis]
Length=589

 Score =  791 bits (2042),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 395/587 (67%), Positives = 467/587 (79%), Gaps = 24/587 (4%)

Query  24   ADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRP  83
            +D    +PVNPCCY PCQH G+CVR+GLD+YQCDCTRTGY G NCT+P  WT +R  LRP
Sbjct  3    SDAFLSSPVNPCCYLPCQHWGVCVRYGLDQYQCDCTRTGYYGENCTVPEFWTRVRLLLRP  62

Query  84   SPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSN  143
            SP   H++LTH +W W+ VN TF+R+ LMRLV+TVRSNL+P PPTYNS + Y++WES SN
Sbjct  63   SPDGAHYILTHFQWLWDIVNHTFLRDFLMRLVITVRSNLVPYPPTYNSKYGYLNWESMSN  122

Query  144  VSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqh  203
            +SYYTRILP VP+DCPTPMG KGK++LPD +LL  R L RR F PDPQGTNLMFAFFAQH
Sbjct  123  LSYYTRILPPVPEDCPTPMGVKGKEELPDPELLVERLLRRRTFRPDPQGTNLMFAFFAQH  182

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKT  +MG GFTKAL HGV  GHIYGD L+RQ QLRL KDGKLK+QVL+GE+YPP
Sbjct  183  FTHQFFKTYNRMGLGFTKALDHGVGAGHIYGDTLDRQLQLRLHKDGKLKFQVLEGEVYPP  242

Query  264  SVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWG  323
            S  + P+ M+YP  IPP+   A+GQE+FG++PGL +YATLWLREHNRVCD+LKAEHPTW 
Sbjct  243  SGMDVPIRMNYPSRIPPEKTFAIGQEMFGIIPGLTMYATLWLREHNRVCDILKAEHPTWD  302

Query  324  DEQLFQTTRLILIGE------------------------TIKIVIEEYVQQLSGYFLQLK  359
            DEQLFQT+RLI+IGE                        TIKIVIEEYVQQLSGY L LK
Sbjct  303  DEQLFQTSRLIIIGEKGWTAVFLPYGTSCLTAALPLAGETIKIVIEEYVQQLSGYLLDLK  362

Query  360  FDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVE  419
            FDP +LF  QFQY NRIA+EF  LYHWHPLMPD F +   E  YEQFL+NTS+L+ YGV+
Sbjct  363  FDPAMLFNTQFQYGNRIALEFTQLYHWHPLMPDRFLIDGDEVLYEQFLYNTSVLIHYGVD  422

Query  420  ALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQE  479
             +V+AFS Q AG+IGGG N+   +  VAV  I+ESR++RLQPFNEYRKRF ++PYTSF+E
Sbjct  423  KMVEAFSLQAAGQIGGGHNVPAMLTDVAVRTIKESRQLRLQPFNEYRKRFNLQPYTSFRE  482

Query  480  LVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPIC  539
                +E+A ELEE YGDIDALE+YPGL+LEK  P +IFGESM+E+GAP+SLKGLLGNPIC
Sbjct  483  FTDNEEIARELEEFYGDIDALEYYPGLMLEKTRPGAIFGESMVEMGAPYSLKGLLGNPIC  542

Query  540  SPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQ  586
            SPEYWKPSTFGG+VGF+IV +ATLK LVC NTKTCP+V+FRVP  +Q
Sbjct  543  SPEYWKPSTFGGKVGFDIVNSATLKDLVCYNTKTCPFVAFRVPKEAQ  589


>gb|AAL37727.1|AF420317_1  cyclooxygenase [Squalus acanthias]
Length=593

 Score =  787 bits (2033),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 385/572 (67%), Positives = 468/572 (81%), Gaps = 2/572 (0%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTH  89
            T +NPCCYYPCQ++GICV  G + Y+CDCTRTGY G NCT P  W+ +   L+PSPS  H
Sbjct  22   TAINPCCYYPCQNKGICVNVGKEGYECDCTRTGYYGVNCTFPFSWSRVHKFLKPSPSSMH  81

Query  90   FLLTHGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYT  148
             +LTH +W W  +N  +F  + LMRLVLTVR+N+IPSPPTYNS + Y+SWE +SN+SY T
Sbjct  82   HVLTHYKWLWYIINNISFFSDTLMRLVLTVRANIIPSPPTYNSDYTYVSWEGYSNISYLT  141

Query  149  RILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqf  208
            R+LP VPKDCPTP GT+G K+LPD++ LA  FLLRRKFIPDPQG+NLMFAFFAQHFTHQF
Sbjct  142  RLLPPVPKDCPTPTGTQGYKKLPDSEQLAEEFLLRRKFIPDPQGSNLMFAFFAQHFTHQF  201

Query  209  fktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEA  268
            F+T    GPGFTKALGHGVDL HIYGD+LERQ+ LRLFKDGKLKYQV++GE++PPSV+EA
Sbjct  202  FRTDLDRGPGFTKALGHGVDLTHIYGDSLERQHHLRLFKDGKLKYQVVNGEVFPPSVKEA  261

Query  269  PVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLF  328
            P+ M YP  +P + ++A+G + FGL+PGLM+YAT+WLREHNRVCD+LK EHP W DEQLF
Sbjct  262  PIQMKYPSTLPEEKRLAIGHDTFGLIPGLMMYATIWLREHNRVCDILKEEHPVWSDEQLF  321

Query  329  QTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHP  388
            QTTRLILIGETIKIVIE+YVQ LSGY  ++ F+PELLF   FQY NRIA+EF+HLYHWHP
Sbjct  322  QTTRLILIGETIKIVIEDYVQHLSGYNFRMMFNPELLFTEHFQYSNRIAVEFDHLYHWHP  381

Query  389  LMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAV  448
            LMPDSF V  Q++SY+ FLFNT +L++ GV+ALV++FS+QIAGRIGGGRN+   +LH+A+
Sbjct  382  LMPDSFIVKGQDFSYKDFLFNTDILLNLGVDALVESFSKQIAGRIGGGRNIHQSLLHIAI  441

Query  449  DVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLL  508
              I   R +R QP+NEYRK+ G+ PY SFQEL GE+E+AA LE+LYG IDA+EFYP LLL
Sbjct  442  ATIEHGRLLRFQPYNEYRKKLGLTPYKSFQELTGEREVAARLEKLYGHIDAMEFYPALLL  501

Query  509  EKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVC  568
            E  + NSIFGESM+E+GAPFSLKGL+GNPICSP+YWKPSTFGG+ GF+IV TAT +KL+C
Sbjct  502  EAPNKNSIFGESMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGKTGFDIVNTATFEKLIC  561

Query  569  LNTKTCPYVSFRVP-DASQDDGPAVERPSTEL  599
            LN K CPYV F VP +   D      +PSTEL
Sbjct  562  LNVKKCPYVGFHVPYNVDNDYEREKGKPSTEL  593


>ref|NP_001020675.1|  prostaglandin-endoperoxide synthase 2b [Danio rerio]
 emb|CAI21290.1|  novel protein similar to prostaglandin-endoperoxide synthase 
2 (ptgs2) [Danio rerio]
 gb|ABF50051.1|  prostaglandin G/H synthase 2b [Danio rerio]
 gb|AAI39569.1|  Prostaglandin-endoperoxide synthase 2b [Danio rerio]
Length=606

 GENE ID: 559020 ptgs2b | prostaglandin-endoperoxide synthase 2b [Danio rerio]
(10 or fewer PubMed links)

 Score =  754 bits (1948),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 369/570 (64%), Positives = 453/570 (79%), Gaps = 3/570 (0%)

Query  30   TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTH  89
            T  NPCC +PCQ++G+C   G D Y+CDCTRTGY G NCT P   TW++ SL+PSP+  H
Sbjct  18   TGANPCCSHPCQNRGVCTEMGSDAYECDCTRTGYYGQNCTTPEFLTWVKVSLKPSPNTVH  77

Query  90   FLLTHGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYT  148
            ++LTH +  W  +N  +F+R  +MR VLT R++LI SPPT+N+ + Y SWE++SN+SYYT
Sbjct  78   YILTHFKSLWNIINNVSFLRNGIMRYVLTSRAHLIDSPPTFNADYGYKSWEAYSNLSYYT  137

Query  149  RILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqf  208
            R LP VP+DCPTPMG  GKK+LPD ++LA + LLRRKFIPDPQ TNLMFAFFAQHFTHQF
Sbjct  138  RTLPPVPRDCPTPMGVAGKKELPDVKMLAEKLLLRRKFIPDPQRTNLMFAFFAQHFTHQF  197

Query  209  fktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEA  268
            FK+  K GP FT AL HGVDL HIYG NL+RQ++LRLFKDGKL+YQ+LDGE+YPP+V E 
Sbjct  198  FKSDMKKGPAFTTALNHGVDLAHIYGQNLDRQHKLRLFKDGKLRYQILDGEVYPPTVSEV  257

Query  269  PVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLF  328
             V MHYP  +P   + AVG E FGL+PGLM+YAT+WLREHNRVCD+LK EHP W DE+LF
Sbjct  258  QVDMHYPPHVPESRRFAVGHEAFGLVPGLMMYATIWLREHNRVCDILKQEHPDWDDERLF  317

Query  329  QTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHP  388
            QT+RLILIGETIKIVIE+YVQ LSGY+ +LKFDPELLF  +FQY+NRI+ EFN LYHWHP
Sbjct  318  QTSRLILIGETIKIVIEDYVQHLSGYYFKLKFDPELLFNERFQYQNRISSEFNTLYHWHP  377

Query  389  LMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAV  448
            LMPD F +  + Y+Y+QFLFNTS+L DYGV +LV++F++QIAGR+ GGRN+   +L VA+
Sbjct  378  LMPDDFHIQDEVYNYQQFLFNTSILTDYGVNSLVESFNKQIAGRVAGGRNVAPAVLRVAI  437

Query  449  DVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLL  508
              I  SR+MR Q  N YRKRF MKPY SF+E+ GEKEMAAELEE+YGD+DA+E Y GLL+
Sbjct  438  KSIENSRQMRYQSINAYRKRFNMKPYRSFEEMTGEKEMAAELEEMYGDVDAVELYAGLLV  497

Query  509  EKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVC  568
            EK   N+IFGE+M+E+GAP+SLKGL+GNPICSPEYWKPSTFGG+VGF IV +A+L+ LVC
Sbjct  498  EKPRSNAIFGETMVEMGAPYSLKGLMGNPICSPEYWKPSTFGGKVGFEIVNSASLQNLVC  557

Query  569  LNTKT-CPYVSFRVPDASQDDGPAVERPST  597
             N    CP  SF VP+  +D  P     ST
Sbjct  558  NNVNGPCPMASFYVPNV-KDSLPTTINAST  586


>dbj|BAF52620.1|  cyclooxygenase-2 [Micropogonias undulatus]
Length=608

 Score =  751 bits (1939),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 365/554 (65%), Positives = 454/554 (81%), Gaps = 2/554 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G+C   G + Y+CDCTRTGY G NCT P   TWL+ +L+PSP+  H+LL
Sbjct  22   NPCCAEPCQNKGVCTSLGAENYECDCTRTGYFGQNCTTPEFLTWLKITLKPSPNTVHYLL  81

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH + FW  VN  +F+R+ +M  VLT RS++I SPPT+N+ + Y  WE++SN+SYYTR L
Sbjct  82   THFKGFWNIVNNISFLRDGIMTYVLTSRSHMIDSPPTFNADYSYKCWEAYSNLSYYTRTL  141

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VPKDCPTPMG  GKK+LPDA++LA + L+RR+FIPDPQGT+LMFAFFAQHFTHQFFK+
Sbjct  142  PPVPKDCPTPMGVVGKKELPDAKVLAEKLLVRRQFIPDPQGTSLMFAFFAQHFTHQFFKS  201

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GP FT + GHGVDL HIYGDNLERQ++LRLFKDGK+KYQ++DGE+YPP+V+E  V 
Sbjct  202  DMKNGPAFTLSKGHGVDLSHIYGDNLERQHKLRLFKDGKMKYQIVDGEVYPPTVQEVGVH  261

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            MHYP  +P   + AVG E FGL+PGLM+YAT+WLREHNRVCD+LK  HP W DE+LFQTT
Sbjct  262  MHYPPHVPDSHRFAVGHEAFGLVPGLMMYATIWLREHNRVCDVLKEVHPDWDDERLFQTT  321

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDP+LLF  +FQY+NRI+ EFN LYHWHPLMP
Sbjct  322  RLILIGETIKIVIEDYVQHLSGYNFKLKFDPQLLFNQRFQYQNRISSEFNTLYHWHPLMP  381

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            DSF++  ++YSY+QF+FNTS++ ++G+  LV++FS+Q+AGR+ GGRN+   ILHVA+  I
Sbjct  382  DSFQIEEKDYSYKQFVFNTSVVTEHGISNLVESFSKQVAGRVAGGRNVPGPILHVAIKSI  441

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             +SR+MR Q  N YRKRF MKPYTSF+++ GEKEMAA LEE+YG IDA+E YPGLL+EK 
Sbjct  442  EDSRKMRYQSLNAYRKRFSMKPYTSFEDMTGEKEMAAVLEEMYGHIDAVELYPGLLVEKP  501

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
              N+IFGE+M+E+GAP+S KGL+GNPICSPEYWKPSTFGG VGF+IV TA+L+KLVC N 
Sbjct  502  RSNAIFGETMVEMGAPYSFKGLMGNPICSPEYWKPSTFGGSVGFDIVNTASLQKLVCNNV  561

Query  572  KT-CPYVSFRVPDA  584
            +  CP  SF VPDA
Sbjct  562  QGPCPVASFHVPDA  575


>ref|XP_422297.1|  PREDICTED: prostaglandin-endoperoxide synthase 2 (prostaglandin 
G/H synthase and cyclooxygenase) isoform 2 [Gallus gallus]
 sp|P27607.1|PGH2_CHICK  RecName: Full=Prostaglandin G/H synthase 2; AltName: Full=Cyclooxygenase-2; 
Short=COX-2; AltName: Full=Prostaglandin-endoperoxide 
synthase 2; AltName: Full=Prostaglandin H2 synthase 
2; Short=PGH synthase 2; Short=PGHS-2; AltName: Full=PHS II; 
AltName: Full=Mitogen-inducible PGHS; Flags: Precursor
 gb|AAA49050.1|  prostaglandin synthase
Length=603

 GENE ID: 396451 PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin
G/H synthase and cyclooxygenase) [Gallus gallus] (10 or fewer PubMed links)

 Score =  751 bits (1938),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 365/550 (66%), Positives = 451/550 (82%), Gaps = 1/550 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G+C+  G DRY+CDCTRTGY G NCT P  +TWL+  L+P+P+  H++L
Sbjct  19   NPCCSLPCQNRGVCMTTGFDRYECDCTRTGYYGENCTTPEFFTWLKLILKPTPNTVHYIL  78

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W  +N  +F+R+ +MR VLT RS+LI SPPTYNS + Y SWE++SN+SYYTR L
Sbjct  79   THFKGVWNIINNISFLRDTIMRYVLTSRSHLIDSPPTYNSDYSYKSWEAYSNLSYYTRSL  138

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P V  DCPTPMG KGKK+LPD++L+  +FLLRRKFIPDPQGTN+MF FFAQHFTHQFFKT
Sbjct  139  PPVGHDCPTPMGVKGKKELPDSKLIVEKFLLRRKFIPDPQGTNVMFTFFAQHFTHQFFKT  198

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GPGFTKA GHGVDL HIYG+ LERQ +LRL KDGKLKYQ++DGEMYPP+V++    
Sbjct  199  DHKKGPGFTKAYGHGVDLNHIYGETLERQLKLRLRKDGKLKYQMIDGEMYPPTVKDTQAE  258

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  +P   Q +VGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DEQLFQTT
Sbjct  259  MIYPPHVPEHLQFSVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDEQLFQTT  318

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRIA EFN LYHWHPL+P
Sbjct  319  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQRFQYQNRIAAEFNTLYHWHPLLP  378

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F++ +QEY+++QFL+N S+++++G+  +V +FS+Q AGR+ GG+N+   +  VA   I
Sbjct  379  DTFQIHNQEYTFQQFLYNNSIMLEHGLSHMVKSFSKQSAGRVAGGKNVPAAVQKVAKASI  438

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             +SR+MR Q  NEYRKRF +KP+ SF+EL GEKEMAAELEELYGDIDA+E YPGLL+EK 
Sbjct  439  DQSRQMRYQSLNEYRKRFMLKPFKSFEELTGEKEMAAELEELYGDIDAMELYPGLLVEKP  498

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             P +IFGE+M+EIGAPFSLKGL+GN ICSPEYWKPSTFGG+VGF I+ TA+L+KL+C N 
Sbjct  499  RPGAIFGETMVEIGAPFSLKGLMGNTICSPEYWKPSTFGGKVGFEIINTASLQKLICNNV  558

Query  572  KTCPYVSFRV  581
            K CP+ +F V
Sbjct  559  KGCPFTAFHV  568


>gb|AAS21313.2|  cyclooxygenase 2 [Fundulus heteroclitus]
Length=610

 Score =  745 bits (1924),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 361/556 (64%), Positives = 452/556 (81%), Gaps = 2/556 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            N CC  PCQ++G+C   G D Y+CDCTRTGY G NCT P   TW++ SL+P+P+  H++L
Sbjct  24   NACCSEPCQNRGVCTAMGSDSYECDCTRTGYRGQNCTTPEFLTWIKISLKPTPNTVHYIL  83

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH + FW  +N  +F+R+ +M+ VLT RS++I SPPTYN+ + Y SWE++SN+SYYTR L
Sbjct  84   THFKGFWNIINNISFLRDAIMKYVLTSRSHMIDSPPTYNADYGYKSWEAYSNLSYYTRAL  143

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VP+DCPTPMG  GKK+LPD ++LA + L+RR+FIPDPQGT+LMFAFFAQHFTHQFFK+
Sbjct  144  PPVPEDCPTPMGVVGKKELPDVKVLAEKLLVRRRFIPDPQGTSLMFAFFAQHFTHQFFKS  203

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GP FT A GHGVDLGHIYG+NLE+Q++LRLFKDGKLKY +++GE+YPP V++  V 
Sbjct  204  DMKNGPAFTVAKGHGVDLGHIYGENLEKQHKLRLFKDGKLKYTMVNGEVYPPLVKDVGVE  263

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            MHYP  +P   + AVG E FGL+PGL++YAT+WLREHNRVCD+LK  HP W DE+LFQTT
Sbjct  264  MHYPPHVPDSQRFAVGHEAFGLVPGLLMYATIWLREHNRVCDVLKGVHPDWDDERLFQTT  323

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRIA EFN LYHWHPLMP
Sbjct  324  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQRFQYQNRIASEFNTLYHWHPLMP  383

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            DSF +  ++YSY++F+FNTS++ ++G+  LVD+FS+QIAGR+ GGRN+   I++VA+  I
Sbjct  384  DSFHIEEKDYSYKEFVFNTSVVTEHGINNLVDSFSKQIAGRVAGGRNVPGPIMYVAIKSI  443

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
              SR+MR Q  N YRKRF MKPYTSF++L GEKEMAA LEELYGD+DA+E YPGLL+EK 
Sbjct  444  ENSRKMRYQSLNAYRKRFSMKPYTSFEDLTGEKEMAAILEELYGDVDAVELYPGLLVEKP  503

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
              N+IFGE+M+E+GAPFSLKGL+GNPICSPEYWKPSTFGG  GF+IV TA+L++LVC N 
Sbjct  504  RTNAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGTAGFDIVNTASLQRLVCNNV  563

Query  572  KT-CPYVSFRVPDASQ  586
            +  CP  SF VPD  +
Sbjct  564  RGPCPVASFYVPDVKE  579


>ref|NP_001025697.1|  prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase 
and cyclooxygenase) [Xenopus (Silurana) tropicalis]
 gb|AAH95912.1|  Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase 
and cyclooxygenase) [Xenopus tropicalis]
 emb|CAJ83938.1|  prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase 
and cyclooxygenase) [Xenopus tropicalis]
Length=604

 GENE ID: 595089 ptgs2 | prostaglandin-endoperoxide synthase 2 (prostaglandin
G/H synthase and cyclooxygenase) [Xenopus (Silurana) tropicalis]
(10 or fewer PubMed links)

 Score =  741 bits (1914),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 361/551 (65%), Positives = 445/551 (80%), Gaps = 1/551 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC  PCQ++G+C+  G DRY+CDCTRTG+ G NCT P   +WLR  L+P+P+  H++
Sbjct  19   ANPCCSNPCQNRGVCMTVGHDRYECDCTRTGFYGENCTKPEFLSWLRLKLKPAPNTVHYI  78

Query  92   LTHGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  VN  +F+R+ +MR VLT RS+LI SPPTYNS + Y SWE+FSN+SYYTR 
Sbjct  79   LTHFKGLWNIVNNISFLRDAIMRYVLTSRSHLIDSPPTYNSHYGYKSWEAFSNLSYYTRT  138

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP V +DCPTPMG KG K+LP A+L+  +FL+RRKFIPDPQG+N+MFAFFAQHFTHQFF+
Sbjct  139  LPPVERDCPTPMGVKGMKELPSAKLVVEKFLMRRKFIPDPQGSNVMFAFFAQHFTHQFFR  198

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T    G  FTKALGHGVDL HIYG++LERQ++LRL K GKLKYQ++ GEMYPP+V+   V
Sbjct  199  TDMAKGAAFTKALGHGVDLNHIYGESLERQHKLRLMKGGKLKYQMISGEMYPPTVKTTGV  258

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  IP   Q AVGQEVFGL+PGLM+Y+T+WLREHNRVCD+L  EHP W DE++FQT
Sbjct  259  DMVYPPHIPDHLQFAVGQEVFGLVPGLMMYSTIWLREHNRVCDILSNEHPEWDDERIFQT  318

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
             RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRI+ EFN LYHWHPL+
Sbjct  319  ARLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQKFQYQNRISAEFNTLYHWHPLL  378

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F +  +EYSY QFL+N S+++++G+  +V++FSRQ AGR+ GGRN    I  VAV  
Sbjct  379  PDTFAISEKEYSYPQFLYNNSVMLNHGLTEMVESFSRQTAGRVAGGRNFPAAITRVAVAS  438

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I  SREMR Q  NEYRKRF +KP+ SF+EL GEKEM+AELE+LYGDIDA+EFYPGLL+E+
Sbjct  439  IEHSREMRYQSLNEYRKRFMLKPFESFEELTGEKEMSAELEKLYGDIDAMEFYPGLLVEQ  498

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P +IFGE+M+EIGAPFSLKGL+GNPICSPEYWKPSTFGG VGF+IV +A+L+KL+C N
Sbjct  499  PRPGAIFGETMVEIGAPFSLKGLMGNPICSPEYWKPSTFGGSVGFDIVNSASLQKLICNN  558

Query  571  TKTCPYVSFRV  581
             + CPY +F V
Sbjct  559  VRDCPYTAFHV  569


>ref|NP_001118139.1|  prostaglandin G/H synthase 2b [Oncorhynchus mykiss]
 gb|ABN11283.1|  prostaglandin G/H synthase 2b [Oncorhynchus mykiss]
Length=609

 GENE ID: 100136699 ptgs2b | prostaglandin G/H synthase 2b [Oncorhynchus mykiss]

 Score =  741 bits (1912),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 359/568 (63%), Positives = 455/568 (80%), Gaps = 2/568 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PC ++G+C   G + Y+CDCTRTG+ G NCT P  +TW++ SL+P+P+  H+LL
Sbjct  23   NPCCSQPCMNRGVCTAMGSEDYECDCTRTGFYGHNCTQPEFFTWIKVSLKPTPNTVHYLL  82

Query  93   THGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            T+ +  W  +N+ +F+R+ +MR VLT RS+LI SPPT+N+ ++Y SWE++SN+SYYTR L
Sbjct  83   TNYKGVWNIINSISFLRDAIMRYVLTSRSHLIDSPPTFNADYNYKSWEAYSNLSYYTRTL  142

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P +PKDCPTPMG  GK +LPDA++LA + L+RRKFIPDPQG++LMFAFFAQHFTHQFFK+
Sbjct  143  PPLPKDCPTPMGVVGKIELPDAKMLAEKLLIRRKFIPDPQGSSLMFAFFAQHFTHQFFKS  202

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              KMGP FTKA GHGVDLGHIYG+NLERQ++LRLFKDGKLK+QVLDGE+YPP+V+E    
Sbjct  203  DQKMGPAFTKAKGHGVDLGHIYGENLERQHKLRLFKDGKLKFQVLDGEVYPPTVKEVGAD  262

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            MHYP  +P   + AVG E FGL+PGLM+YAT+WLREHNRVCD+LK  HP W D++LFQT+
Sbjct  263  MHYPPHVPESHRFAVGHEAFGLVPGLMMYATIWLREHNRVCDVLKEVHPDWDDDRLFQTS  322

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRI+ EFN LYHWHPLMP
Sbjct  323  RLILIGETIKIVIEDYVQHLSGYNFKLKFDPELLFKERFQYQNRISSEFNTLYHWHPLMP  382

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F +  Q YSY QF+FNTS++  +G+  LV +F++QIAGR+ GGRN+   ++ VA+  I
Sbjct  383  DAFHIQEQVYSYPQFVFNTSVVTTHGISNLVASFTKQIAGRVAGGRNVPPAVMMVALKSI  442

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
              SR+MR Q  N YRKRF MKPY SF++L GEKEMAAELEE+YG +DA+E YPGLL+EK 
Sbjct  443  ENSRQMRYQSLNAYRKRFSMKPYASFEDLTGEKEMAAELEEMYGHVDAVELYPGLLVEKP  502

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
              N+IFGE+M+E+GAP+SLKGL+GNPICSPEYWKPSTFGG VGF+I+ TA+L++LVC N 
Sbjct  503  RTNAIFGETMVEMGAPYSLKGLMGNPICSPEYWKPSTFGGSVGFDIINTASLQRLVCSNV  562

Query  572  KT-CPYVSFRVPDASQDDGPAVERPSTE  598
            K  CP  SF VPD   +    +   + +
Sbjct  563  KGPCPVASFHVPDVEDNRSNTINSSTAQ  590


>ref|NP_001086946.1|  prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase 
and cyclooxygenase) [Xenopus laevis]
 gb|AAH77809.1|  Ptgs2-prov protein [Xenopus laevis]
Length=604

 GENE ID: 446781 ptgs2 | prostaglandin-endoperoxide synthase 2 (prostaglandin
G/H synthase and cyclooxygenase) [Xenopus laevis] (10 or fewer PubMed links)

 Score =  738 bits (1906),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 355/551 (64%), Positives = 446/551 (80%), Gaps = 1/551 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
             NPCC  PCQ+QG+C+  G DRY+CDCTRTG+ G NCT P   +WLR  L+P+P+  H++
Sbjct  19   ANPCCSNPCQNQGVCMTVGFDRYECDCTRTGFYGENCTKPEFLSWLRLKLKPTPNTVHYI  78

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            L+H +  W  VN+ +F+R+ +MR VLT RS+LI SPPTYNS + Y +WE++SN+SYYTR 
Sbjct  79   LSHFKGVWNIVNSMSFLRDAIMRYVLTSRSHLIDSPPTYNSHYTYKNWETYSNLSYYTRS  138

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP V +DCPTPMG KG K+LP ++L+  +FL+RRKFIPDPQGTN+MFAFFAQHFTHQFFK
Sbjct  139  LPPVERDCPTPMGVKGLKELPSSKLVVEKFLMRRKFIPDPQGTNVMFAFFAQHFTHQFFK  198

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            T    G  FTKALGHGVDL H+YG++LERQ++LRL K GKLKYQ++DG+MYPP+V+ + V
Sbjct  199  TDMAKGAAFTKALGHGVDLNHVYGESLERQHKLRLMKGGKLKYQMIDGDMYPPTVKSSGV  258

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             M YP  +P   Q AVGQEVFGL+PGLM+Y+T+WLREHNRVCD+L  EHP W DE++FQT
Sbjct  259  DMAYPPHVPEHVQFAVGQEVFGLVPGLMMYSTIWLREHNRVCDILAGEHPEWDDERIFQT  318

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
             RLILIGETIKIVIE+YVQ LSGY  +LKFDP+LLF  +FQY+NRIA EFN LYHWHPL+
Sbjct  319  ARLILIGETIKIVIEDYVQHLSGYHFKLKFDPQLLFNQRFQYQNRIAAEFNTLYHWHPLL  378

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F +  +EYSY QFL+N S+++D+G+  +V++FSRQ AGR+ GGRN    I  VAV  
Sbjct  379  PDTFAINEKEYSYPQFLYNNSVMIDHGLTQMVESFSRQSAGRVAGGRNFPAAITRVAVAS  438

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I  SREMR Q  NEYRKRF +KP+ +F+EL GEKEM+AELE+LYGDIDA+E YPGLL+E+
Sbjct  439  IEHSREMRYQSLNEYRKRFMLKPFETFEELTGEKEMSAELEKLYGDIDAMELYPGLLVEQ  498

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P +IFGE+M+E+GAPFSLKGL+GNPICSPEYWKPSTFGG VGF+IV +A+ +KL+C N
Sbjct  499  PRPGAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGSVGFDIVNSASFQKLICNN  558

Query  571  TKTCPYVSFRV  581
             + CPY +F V
Sbjct  559  VRDCPYTAFHV  569


>gb|ACH73267.1|  cyclooxygenase-2b [Myoxocephalus octodecemspinosus]
Length=605

 Score =  738 bits (1905),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 363/567 (64%), Positives = 452/567 (79%), Gaps = 3/567 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G+C   G D Y+CDCTRTGY G NCT P   TW++ SL+PSP+  H++L
Sbjct  22   NPCCSEPCQNRGVCTALGTDNYECDCTRTGYHGHNCTTPEFLTWVKISLKPSPNTVHYIL  81

Query  93   THGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH + FW  +N+ +F R+ +MR VLT RS+LI SPPT+N+ + Y SWE++SN+SYYTR L
Sbjct  82   THFKGFWNIINSISFFRDAIMRYVLTSRSHLIDSPPTFNADYGYKSWEAYSNLSYYTRTL  141

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VP+DCPTPMG  GKK+LPDA+LLA +  +RR+FIPDPQGT+LMFAFFAQHFTHQFFK+
Sbjct  142  PPVPEDCPTPMGVVGKKELPDAKLLAEKLFMRRQFIPDPQGTSLMFAFFAQHFTHQFFKS  201

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GP FT A GHGVDL H+YG ++ERQ++LRL +DGKLKYQVLDGE+YPP+V+E    
Sbjct  202  DMKKGPAFTLATGHGVDLNHVYGGSMERQHKLRLRQDGKLKYQVLDGEVYPPTVKEVGAD  261

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            MHYP  +P   + AVG E FGL+PGLM+YAT+WLREHNRVCD+LK  HP W DE+LFQTT
Sbjct  262  MHYPPHVPESHRFAVGHEAFGLVPGLMMYATIWLREHNRVCDVLKEVHPDWDDERLFQTT  321

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRIA EFN LYHWHPLMP
Sbjct  322  RLILIGETIKIVIEDYVQHLSGYNFKLKFDPELLFNQRFQYQNRIASEFNTLYHWHPLMP  381

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            DSF +  ++YSY++F+FNTS++ ++G+  LV++F+ QIAGR+ GGRN+   I++VA+  I
Sbjct  382  DSFHIEEKDYSYKEFVFNTSVVTEHGIGNLVESFTNQIAGRVAGGRNVPGPIMYVAIKSI  441

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
              SR+MR Q  N YRKRF MKPY+SF+++ GEKEMAA LEE YG +DA+E YPGLL+EK 
Sbjct  442  ENSRKMRYQSLNAYRKRFSMKPYSSFEDMTGEKEMAAILEEFYGHVDAVELYPGLLVEKP  501

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
              N+IFGE+M+E+GAPFSLKGL+GNPICSPEYWKPSTFGG  GFNIV TA+L++LVC N 
Sbjct  502  RSNAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGSEGFNIVNTASLQRLVCNNV  561

Query  572  KT-CPYVSFRVPDASQDDGPAVERPST  597
            +  CP  SF  PD  +D G  +   ST
Sbjct  562  QGPCPVASFSGPDV-KDSGSMIINSST  587


>gb|AAD45896.1|AF158373_1  prostaglandin endoperoxide synthase-2; cyclooxygenase-2 [Salvelinus 
fontinalis]
Length=607

 Score =  729 bits (1883),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 355/554 (64%), Positives = 447/554 (80%), Gaps = 2/554 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
            V+PCC  PC+++G+C   G D Y+CDCTRTGY G NCT P   TW++ SL+P+P+  H++
Sbjct  21   VDPCCAQPCENRGLCNSKGFDNYECDCTRTGYYGKNCTTPEFLTWIKISLKPAPNTVHYI  80

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  +N  TF+R  +M  VLT RS+L+ SPPTYN+ + Y SWE++SN+SYYTR 
Sbjct  81   LTHYKGLWNVINKITFVRNAIMSYVLTSRSHLVDSPPTYNADYGYKSWEAYSNLSYYTRT  140

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP +PKDCPTPMGT G+  LPD +L+  + LLR++FIPDPQG+NLMFAFFAQHFTHQFFK
Sbjct  141  LPPLPKDCPTPMGTAGRAVLPDVKLVVEKVLLRKRFIPDPQGSNLMFAFFAQHFTHQFFK  200

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            +  K GP FTKALGHGVDL H+YGD+LERQ++LRLFKDGKLKYQVL+GE+YPP V E   
Sbjct  201  SDLKKGPAFTKALGHGVDLNHVYGDSLERQHKLRLFKDGKLKYQVLNGEVYPPLVREVGA  260

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             MHYP  +P + + AVG E FGL+PGLM+YAT+WLREHNRVCD+L+ EHP W DE++FQT
Sbjct  261  EMHYPPQVPEEHRFAVGHEHFGLVPGLMMYATIWLREHNRVCDVLRQEHPEWDDERIFQT  320

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            TRLILIGETIKIVIE+YVQ LSGY  QLKFDPELLF  +FQY+NRIA EFN LYHWHPLM
Sbjct  321  TRLILIGETIKIVIEDYVQHLSGYHFQLKFDPELLFNQRFQYQNRIAAEFNTLYHWHPLM  380

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F +  + Y+Y QF+FN S++ ++G+  LV++F++QIAGR+ GGRN+   ++ VA   
Sbjct  381  PDTFSIEDRAYTYPQFVFNNSLVTEHGITNLVESFTKQIAGRVAGGRNLPPALVAVAAKA  440

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            +  SR+MR Q  N YRKRF M+ YTSF++L GE E+AAELE LYGD+DA+E YPGLL+E+
Sbjct  441  LEHSRDMRYQSLNAYRKRFNMRAYTSFEDLTGETELAAELESLYGDVDAVELYPGLLVER  500

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              PN++FGE+M+E+GAP+SLKGLLGNPICSPEYW PSTFGG VGF+IV TA+L++LVC N
Sbjct  501  PRPNAVFGETMVEMGAPYSLKGLLGNPICSPEYWMPSTFGGSVGFDIVNTASLERLVCSN  560

Query  571  TK-TCPYVSFRVPD  583
             K +CP VSF+VPD
Sbjct  561  VKGSCPMVSFQVPD  574


>ref|NP_001117820.1|  cyclooxygenase-2 [Oncorhynchus mykiss]
 emb|CAB46017.1|  cyclooxygenase-2 [Oncorhynchus mykiss]
Length=607

 GENE ID: 100136025 cox-2 | cyclooxygenase-2 [Oncorhynchus mykiss]

 Score =  727 bits (1876),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 350/554 (63%), Positives = 444/554 (80%), Gaps = 2/554 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
            V+PCC  PC+++G+C   G D Y+CDCTRTGY G NCT P   TW++ SL+P+P+  H++
Sbjct  21   VDPCCAQPCENRGLCNSKGFDNYECDCTRTGYYGKNCTTPEFLTWIKISLKPAPNTIHYI  80

Query  92   LTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  +N  TF+R  +M  VLT RS+L+ SPPTYN+ + Y SWE++SN+ YYTR 
Sbjct  81   LTHYKGLWNVINKITFVRNAIMSYVLTPRSHLVDSPPTYNADYGYKSWEAYSNLFYYTRT  140

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP +PKDCPTPMGT G+  LPD +L+  + LLR++FIPDPQG+NLMFAFFAQHFTHQFFK
Sbjct  141  LPPLPKDCPTPMGTAGRAVLPDVKLVVEKVLLRKRFIPDPQGSNLMFAFFAQHFTHQFFK  200

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            +    GP FTKALGHGVDL H+YGD LERQ++LRLFKDGKLKY+VL+GE+YPP V E   
Sbjct  201  SDFMKGPAFTKALGHGVDLNHVYGDTLERQHKLRLFKDGKLKYRVLNGEVYPPLVREVGA  260

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             MHYP  +P + + AVG E FGL+PGLM+YAT+WLREHNRVCD+L+ EHP W DE++FQT
Sbjct  261  EMHYPPQVPEEHRFAVGHEHFGLVPGLMMYATIWLREHNRVCDVLRQEHPEWDDERIFQT  320

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            TRLILIGETIKIVIE+YVQ LSGY  QLKFDPELLF  +FQY+NRIA EFN LYHWHPLM
Sbjct  321  TRLILIGETIKIVIEDYVQHLSGYHFQLKFDPELLFNQRFQYQNRIAAEFNTLYHWHPLM  380

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            P++F +  + Y+Y QF+FN S++ ++G+  LV++F++QIAGR+ GGRN+   ++ VA   
Sbjct  381  PETFSIEDRAYTYPQFVFNNSLVTEHGINNLVESFTKQIAGRVAGGRNLPPALVGVAAKA  440

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            +  SR+MR Q  N YRKRF M+ YTSF++L GE E+AAELE LYGD+DA+E YPGLL+E+
Sbjct  441  LEHSRDMRYQSLNAYRKRFNMRVYTSFEDLTGETELAAELESLYGDVDAVELYPGLLVER  500

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              PN++FGE+M+E+GAP+SLKGLLGNPICSPEYW PSTFGG VGF+I+ TA+L++LVC N
Sbjct  501  PRPNAVFGETMVEMGAPYSLKGLLGNPICSPEYWMPSTFGGSVGFDILNTASLERLVCNN  560

Query  571  TK-TCPYVSFRVPD  583
             K +CP VSF+VPD
Sbjct  561  VKGSCPMVSFQVPD  574


>ref|XP_001231379.1|  PREDICTED: prostaglandin-endoperoxide synthase 2 (prostaglandin 
G/H synthase and cyclooxygenase) isoform 1 [Gallus gallus]
Length=571

 GENE ID: 396451 PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin
G/H synthase and cyclooxygenase) [Gallus gallus] (10 or fewer PubMed links)

 Score =  726 bits (1874),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 356/533 (66%), Positives = 438/533 (82%), Gaps = 1/533 (0%)

Query  50   GLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVN-ATFIR  108
            G DRY+CDCTRTGY G NCT P  +TWL+  L+P+P+  H++LTH +  W  +N  +F+R
Sbjct  4    GFDRYECDCTRTGYYGENCTTPEFFTWLKLILKPTPNTVHYILTHFKGVWNIINNISFLR  63

Query  109  EMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKK  168
            + +MR VLT RS+LI SPPTYNS + Y SWE++SN+SYYTR LP V  DCPTPMG KGKK
Sbjct  64   DTIMRYVLTSRSHLIDSPPTYNSDYSYKSWEAYSNLSYYTRSLPPVGHDCPTPMGVKGKK  123

Query  169  QLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffktSGKMGPGFTKALGHGVD  228
            +LPD++L+  +FLLRRKFIPDPQGTN+MF FFAQHFTHQFFKT  K GPGFTKA GHGVD
Sbjct  124  ELPDSKLIVEKFLLRRKFIPDPQGTNVMFTFFAQHFTHQFFKTDHKKGPGFTKAYGHGVD  183

Query  229  LGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQ  288
            L HIYG+ LERQ +LRL KDGKLKYQ++DGEMYPP+V++    M YP  +P   Q +VGQ
Sbjct  184  LNHIYGETLERQLKLRLRKDGKLKYQMIDGEMYPPTVKDTQAEMIYPPHVPEHLQFSVGQ  243

Query  289  EVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYV  348
            EVFGL+PGLM+YAT+WLREHNRVCD+LK EHP W DEQLFQTTRLILIGETIKIVIE+YV
Sbjct  244  EVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDEQLFQTTRLILIGETIKIVIEDYV  303

Query  349  QQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLF  408
            Q LSGY  +LKFDPELLF  +FQY+NRIA EFN LYHWHPL+PD+F++ +QEY+++QFL+
Sbjct  304  QHLSGYHFKLKFDPELLFNQRFQYQNRIAAEFNTLYHWHPLLPDTFQIHNQEYTFQQFLY  363

Query  409  NTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKR  468
            N S+++++G+  +V +FS+Q AGR+ GG+N+   +  VA   I +SR+MR Q  NEYRKR
Sbjct  364  NNSIMLEHGLSHMVKSFSKQSAGRVAGGKNVPAAVQKVAKASIDQSRQMRYQSLNEYRKR  423

Query  469  FGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPF  528
            F +KP+ SF+EL GEKEMAAELEELYGDIDA+E YPGLL+EK  P +IFGE+M+EIGAPF
Sbjct  424  FMLKPFKSFEELTGEKEMAAELEELYGDIDAMELYPGLLVEKPRPGAIFGETMVEIGAPF  483

Query  529  SLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRV  581
            SLKGL+GN ICSPEYWKPSTFGG+VGF I+ TA+L+KL+C N K CP+ +F V
Sbjct  484  SLKGLMGNTICSPEYWKPSTFGGKVGFEIINTASLQKLICNNVKGCPFTAFHV  536


>gb|ACH73268.1|  cyclooxygenase-2 [Myxine glutinosa]
Length=610

 Score =  715 bits (1845),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 353/558 (63%), Positives = 443/558 (79%), Gaps = 2/558 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            +PCC  PC+++G+CV  G + Y+CDCTRTGY G NCT P  WTW+ N L+P P   H+ L
Sbjct  23   DPCCGSPCENKGVCVSVGFEDYECDCTRTGYYGSNCTYPETWTWIVNMLKPLPDTVHYFL  82

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH   FW  VN A F+R+ +MR VL  R++++ SPPTYN+ + Y SWE++SN+SY+TR+L
Sbjct  83   THFAPFWSLVNRAAFLRDRVMRHVLMSRAHMVSSPPTYNADYGYKSWEAYSNLSYFTRLL  142

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VP+ CPTPMG  GKK+LPDAQ L  RFLLRR FIPDPQG+NL+FAFFAQHFTHQFFKT
Sbjct  143  PPVPQGCPTPMGRTGKKELPDAQKLXERFLLRRTFIPDPQGSNLLFAFFAQHFTHQFFKT  202

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GPGFTKALGHGVDL HIYGD L++Q++LRL  +GKLK+Q++DGE++PP V EAPV 
Sbjct  203  DFKRGPGFTKALGHGVDLSHIYGDTLDKQHKLRLHNNGKLKFQMIDGEVFPPLVSEAPVD  262

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  +P  ++ AVG E FGL+PGLMLY TLWLREHNRVCD+L  +HP W DE++FQT 
Sbjct  263  MIYPPHVPEAARFAVGHEAFGLVPGLMLYGTLWLREHNRVCDVLDVDHPEWDDERIFQTA  322

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDP+LLFG  FQY NRI++EFNHLYHWH L P
Sbjct  323  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPKLLFGQPFQYSNRISVEFNHLYHWHGLNP  382

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F+VG+QEY Y QFLFN ++L+++GV  L++AF+ Q AGRIGGG+N+   +LHVA   I
Sbjct  383  DAFRVGTQEYQYSQFLFNNTILLNHGVRGLLEAFNVQQAGRIGGGQNIHGALLHVATASI  442

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
            +  R+MR Q  N+YRK+FG++PY SF++L GE EMAA+L ELY DI+A+EFY GL++EK 
Sbjct  443  KHGRKMRFQSLNQYRKQFGLQPYQSFEQLTGETEMAADLAELYSDINAMEFYLGLMVEKP  502

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
               ++FGE+M+E GAPFSLKGL+GN ICSPEYWKPSTFGG  GF IV +A+L++LVCLN 
Sbjct  503  RQGALFGETMVEAGAPFSLKGLMGNAICSPEYWKPSTFGGNRGFEIVNSASLRRLVCLNL  562

Query  572  KT-CPYVSFRVPDASQDD  588
            +  CP V+F VP  +Q D
Sbjct  563  QGPCPDVAFHVPRDNQQD  580


>ref|NP_705943.1|  prostaglandin-endoperoxide synthase 2 [Danio rerio]
 gb|AAK33031.1|  prostaglandin G/H synthase 2 [Danio rerio]
 gb|AAH56736.1|  Prostaglandin-endoperoxide synthase 2a [Danio rerio]
Length=601

 GENE ID: 246227 ptgs2a | prostaglandin-endoperoxide synthase 2a [Danio rerio]
(Over 10 PubMed links)

 Score =  708 bits (1827),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 339/554 (61%), Positives = 446/554 (80%), Gaps = 9/554 (1%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            +PCC  PCQ+QG+C+  G D Y+CDCTRTGY G NCT P L T ++++L+P P+  H +L
Sbjct  22   DPCCAQPCQNQGVCLSKGADAYECDCTRTGYYGENCTTPELLTRIKSALKPRPNVVHHIL  81

Query  93   THGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W+ +N+ +++R+ +MR +L  RS+L+ SPPTYN+ + Y SWE++SN+SYYTR L
Sbjct  82   THYKSIWDIINSISYLRDGIMRYILLSRSHLVESPPTYNADYGYKSWEAYSNLSYYTRTL  141

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
              +P++CPTP        LP+A+ +  + LLR++FIPDPQ ++LMFAFFAQHF+HQFFK+
Sbjct  142  APLPQNCPTP-------DLPNAKQVVEQVLLRKQFIPDPQRSSLMFAFFAQHFSHQFFKS  194

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GP FTKALGHGVDLGHIYG+ LE Q++LRLFKDGKLKYQV+DGE+YPP V++  V 
Sbjct  195  DFKKGPAFTKALGHGVDLGHIYGETLEVQHKLRLFKDGKLKYQVVDGEVYPPLVKDVQVE  254

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            MHYP  IP + + AVG E FGL+PGLM+YAT+WLREHNRVCD++K EHP W DE++FQTT
Sbjct  255  MHYPPHIPEEQKFAVGHEAFGLVPGLMMYATIWLREHNRVCDIMKQEHPDWDDERIFQTT  314

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPEL+F  +FQY+NRIA EFN LYHWHPL+P
Sbjct  315  RLILIGETIKIVIEDYVQHLSGYNFKLKFDPELIFSERFQYQNRIAAEFNTLYHWHPLLP  374

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F++  Q Y Y QF+FN S++  +G+  +VD+F++Q AGR+ GGRN+   +  VAV V+
Sbjct  375  DNFQIQDQIYGYHQFVFNNSIVTTHGIRNMVDSFTKQTAGRVSGGRNLPPAVQGVAVKVL  434

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             ++R+MR Q FN YR+RF MKPY+SF+E+ G+K++AA+L+ELYG +D +E YPGLL+EK 
Sbjct  435  EQTRQMRYQSFNAYRRRFNMKPYSSFEEMTGDKDLAAQLKELYGHVDKVELYPGLLVEKS  494

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN-  570
             PNS+FGE+M+E+GAP+SLKGL+GN ICSPEYWKPSTFGG+VGF+IV +A+LKKLVCLN 
Sbjct  495  RPNSVFGETMVEMGAPYSLKGLMGNAICSPEYWKPSTFGGKVGFDIVNSASLKKLVCLNI  554

Query  571  TKTCPYVSFRVPDA  584
            +  CP VSF+VPD 
Sbjct  555  SGPCPMVSFQVPDV  568


>gb|AAH63232.1|  Prostaglandin-endoperoxide synthase 2a [Danio rerio]
Length=601

 GENE ID: 246227 ptgs2a | prostaglandin-endoperoxide synthase 2a [Danio rerio]
(Over 10 PubMed links)

 Score =  707 bits (1824),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 338/554 (61%), Positives = 445/554 (80%), Gaps = 9/554 (1%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            +PCC  PCQ+QG+C+  G D Y+CDCTRTGY G NCT P L T ++++L+P P+  H +L
Sbjct  22   DPCCAQPCQNQGVCLSKGADAYECDCTRTGYYGENCTTPELLTRIKSALKPRPNVVHHIL  81

Query  93   THGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +  W+ +N+ +++R+ +MR +L  RS+L+ SPPTYN+ + Y SWE++SN+SYYTR L
Sbjct  82   THYKSIWDIINSISYLRDGIMRYILLSRSHLVESPPTYNADYGYKSWEAYSNLSYYTRTL  141

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
              +P++CPTP        LP+A+ +  + LLR++FIPDPQ ++LMFAFFAQHF+HQFFK+
Sbjct  142  APLPQNCPTP-------DLPNAKQVVEQVLLRKQFIPDPQRSSLMFAFFAQHFSHQFFKS  194

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GP FTKALGHGVDLGHIYG+ LE Q++LRLFKDGKLKYQV+DGE+YPP V++  V 
Sbjct  195  DFKKGPAFTKALGHGVDLGHIYGETLEVQHKLRLFKDGKLKYQVVDGEVYPPLVKDVQVE  254

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            MHYP  IP + + AVG E FGL+PGL++YAT+WLREHNRVCD++K EHP W DE++FQTT
Sbjct  255  MHYPPHIPEEQKFAVGHEAFGLVPGLIMYATIWLREHNRVCDIMKQEHPDWDDERIFQTT  314

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPEL+F  +FQY+NRIA EFN LYHWHPL+P
Sbjct  315  RLILIGETIKIVIEDYVQHLSGYNFKLKFDPELIFSERFQYQNRIAAEFNTLYHWHPLLP  374

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D+F++  Q Y Y QF+FN S++  +G+  +VD+F++Q AGR+ GGRN+   +  VAV V+
Sbjct  375  DNFQIQDQIYGYHQFVFNNSIVTTHGIRNMVDSFTKQTAGRVSGGRNLPPAVQGVAVKVL  434

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
             ++R+MR Q FN YR+RF MKPY+SF+E+ G+K++AA+L+ELYG +D +E YPGLL+EK 
Sbjct  435  EQTRQMRYQSFNAYRRRFNMKPYSSFEEMTGDKDLAAQLKELYGHVDKVELYPGLLVEKS  494

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
             PNS+FGE+M+E+GAP+SLKGL+GN ICSPEYWKPSTFGG+VGF+IV +A+LKKLVCLN 
Sbjct  495  RPNSVFGETMVEMGAPYSLKGLMGNAICSPEYWKPSTFGGKVGFDIVNSASLKKLVCLNV  554

Query  572  KT-CPYVSFRVPDA  584
               CP VSF+VPD 
Sbjct  555  SGPCPMVSFQVPDV  568


>emb|CAF74800.1|  cyclo-oxygenase-2 [Dicentrarchus labrax]
Length=596

 Score =  678 bits (1749),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 339/553 (61%), Positives = 422/553 (76%), Gaps = 4/553 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
              PCC  PCQ++G C   G D Y+CDCTRTGY G NCT P   T L+  L+P+P+  H++
Sbjct  19   AQPCCSIPCQNRGACAGNGFDNYECDCTRTGYYGRNCTTPEFITQLK-PLKPAPNTAHYI  77

Query  92   LTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI  150
            LTH +  W  +N   F+R+++M  VLT RS LI SPPTYN  + Y SWE++SN+SYYTRI
Sbjct  78   LTHSKGVWNVINLIPFVRQVIMVYVLTGRSPLIDSPPTYNVEYGYKSWEAYSNLSYYTRI  137

Query  151  LPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffk  210
            LP V +DCPTP+G  GK  LPD++    + L + +FIPDPQGTN+MFAFFAQHFTHQFFK
Sbjct  138  LPPVARDCPTPIGVVGKIALPDSKTAVEKLLRK-RFIPDPQGTNIMFAFFAQHFTHQFFK  196

Query  211  tSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPV  270
            +  K GP FT A GHGVDL HIYGD LERQ++LRLFKDGKLKYQ+++GEMYPP+V+E   
Sbjct  197  SDMKKGPAFTVAKGHGVDLSHIYGDKLERQHKLRLFKDGKLKYQMVNGEMYPPTVKEVGA  256

Query  271  LMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQT  330
             MHYP  +P   + AVG E FGL+PGLM+YAT+WLREHNRVCD+L+ EHP W DE  FQT
Sbjct  257  EMHYPPHVPEAHRFAVGHEAFGLVPGLMMYATIWLREHNRVCDILQQEHPEWDDELSFQT  316

Query  331  TRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM  390
            +RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRI +EFN LYHWHPL+
Sbjct  317  SRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNSRFQYQNRI-VEFNTLYHWHPLL  375

Query  391  PDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV  450
            PD+F +G + YSY QF+FN S   ++G++ LV +F+ QIAGR+ GGRN+   +  VA +V
Sbjct  376  PDTFLIGEEVYSYGQFVFNNSSAPEHGIKRLVSSFTNQIAGRVAGGRNIPLALGPVATEV  435

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEK  510
            I  SR+MR Q  N YRKRF ++PY+SF++L GE E+AAELE LY D D +E YP LL+EK
Sbjct  436  IDYSRDMRYQSLNVYRKRFELRPYSSFEDLTGEPEIAAELEPLYADADIVELYPALLVEK  495

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P + FGE+M+E+GAP+SLKGL+GN ICSP YWKPSTFGG VGF+I+ TA+L+ L+C N
Sbjct  496  PRPTAPFGETMVELGAPYSLKGLMGNLICSPLYWKPSTFGGVVGFSILNTASLESLICNN  555

Query  571  TKTCPYVSFRVPD  583
             K CP  SF VPD
Sbjct  556  VKGCPIASFEVPD  568


>gb|ACH73266.1|  cyclooxygenase-1a [Fundulus heteroclitus]
Length=452

 Score =  623 bits (1606),  Expect = 1e-177, Method: Compositional matrix adjust.
 Identities = 326/451 (72%), Positives = 378/451 (83%), Gaps = 0/451 (0%)

Query  143  NVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaq  202
            N+SYYTR+LP VPKDCP PMGTKGK  LPD + ++ R+  R +F PDPQGTNLMFAF AQ
Sbjct  1    NLSYYTRLLPPVPKDCPLPMGTKGKPVLPDIKEISERYFKRTEFRPDPQGTNLMFAFMAQ  60

Query  203  hfthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYP  262
            HFTHQFFKTS K+  GFTKALGHGVD  +IYG+ LERQ+QLRL KDGKLKYQ+++GEMYP
Sbjct  61   HFTHQFFKTSHKVDAGFTKALGHGVDASNIYGEELERQHQLRLHKDGKLKYQLINGEMYP  120

Query  263  PSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTW  322
            P+V E PV M YP G P + ++A+GQEVFGL+PGL +YAT+WLREHNRVCD+LK EHPTW
Sbjct  121  PTVSEVPVHMVYPEGFPAEQRLAIGQEVFGLVPGLTVYATIWLREHNRVCDILKGEHPTW  180

Query  323  GDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNH  382
             DEQLFQT RLI+IGE I I+IEEYVQ LSGY+L+LK+DP LLFGV+FQY NRIA+EF +
Sbjct  181  DDEQLFQTARLIIIGEIINIIIEEYVQHLSGYYLKLKYDPSLLFGVRFQYTNRIALEFCY  240

Query  383  LYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHH  442
            LYHWHPLMPDSF +   E  Y QFL+NTS+L+ YGVE LVDAFSRQ AG+IGGGRN+   
Sbjct  241  LYHWHPLMPDSFLIDGDELPYSQFLYNTSILMHYGVEKLVDAFSRQPAGQIGGGRNIHQA  300

Query  443  ILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEF  502
            +L VA  VIR+SR  RLQPFN+YRKRF +KPY+SF EL G++EMA  LEELYGDIDALEF
Sbjct  301  VLRVAEMVIRDSRAARLQPFNQYRKRFNLKPYSSFYELTGDEEMARGLEELYGDIDALEF  360

Query  503  YPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTAT  562
            YPGLLLEK  P+SIFGESM+E+GAPFSLKGLLGNPI SPEYWKPSTFGGE GFNI+KT+T
Sbjct  361  YPGLLLEKTRPSSIFGESMVEMGAPFSLKGLLGNPINSPEYWKPSTFGGETGFNIIKTST  420

Query  563  LKKLVCLNTKTCPYVSFRVPDASQDDGPAVE  593
            LKKLVCLNTK CPYV F VP   ++  P+ E
Sbjct  421  LKKLVCLNTKWCPYVDFHVPRNEEERKPSTE  451


>ref|XP_002239720.1|  hypothetical protein BRAFLDRAFT_129952 [Branchiostoma floridae]
 gb|EEA40758.1|  hypothetical protein BRAFLDRAFT_129952 [Branchiostoma floridae]
Length=710

 GENE ID: 7256197 BRAFLDRAFT_129952 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  605 bits (1561),  Expect = 1e-172, Method: Compositional matrix adjust.
 Identities = 322/568 (56%), Positives = 408/568 (71%), Gaps = 6/568 (1%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ+ G+C+R G D Y CDCTRTGY G NC IP  WT ++ +L+PS   TH LL
Sbjct  21   NPCCSMPCQNMGVCMREG-DSYSCDCTRTGYYGQNCDIPEFWTSIKVALKPSKKTTHHLL  79

Query  93   THGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            T+ +W W  VN   F+ + +MR V  +RS  + SPP Y++ HDY SW+++++ SYYTR L
Sbjct  80   TNYKWLWNIVNRIPFLSKFIMRAVYKIRSATVDSPPMYHTGHDYTSWDTYADRSYYTRAL  139

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VP  CPTPMGT G+K+LP  Q +A  FL RR+FIPD + TN++F F AQHFTHQFFKT
Sbjct  140  PPVPPGCPTPMGTAGRKELPSPQYIAETFLARRRFIPDKRRTNVLFNFMAQHFTHQFFKT  199

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K G G T    HGVDL HIYG+ +ERQ+QLR F DGKLK+Q ++GE+YPPS+ +APV 
Sbjct  200  DFKKGAGRTWG-DHGVDLSHIYGETVERQHQLRSFTDGKLKFQRVEGEVYPPSLADAPVH  258

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  +P   + A+G E FGLLPGL +Y+T+WLREHNRVCD++K  HP W DE+LFQT 
Sbjct  259  MIYPPYVPEGKRFAIGHEFFGLLPGLFVYSTVWLREHNRVCDVMKELHPDWDDERLFQTA  318

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLIL GETI I+I EYVQ LSGY   L +DPELLF  QFQY+NRI +EFNHLYHWHPLMP
Sbjct  319  RLILTGETINIIINEYVQHLSGYNFDLFWDPELLFSDQFQYQNRIFVEFNHLYHWHPLMP  378

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D F +    Y  + +LFNT ++  +G    VDA SRQIAG+I G +N+    L VAV+ I
Sbjct  379  DQFHINGSTYGMKDYLFNTDLVFKHGFGTTVDAMSRQIAGQI-GPKNIGPVNLKVAVETI  437

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELV-GEKEMAAELEELYGDIDALEFYPGLLLEK  510
            +  R +R+Q  N+YRKRFG+ PY +F EL  G+ EMA +LEE YGD+DA+E Y GL++E+
Sbjct  438  KHERNLRMQGLNQYRKRFGIPPYKTFLELTGGDAEMADQLEEAYGDVDAVELYVGLMVEQ  497

Query  511  CHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
              P S+  E++IE+G PFS+KGLL NP+CSP++WKPSTFGGE GF +VKTATLK L C N
Sbjct  498  PAPGSVTSETIIEMGGPFSVKGLLSNPLCSPQWWKPSTFGGEAGFRMVKTATLKDLFCRN  557

Query  571  TKT-CPYVSFRVPDASQDDGPAVERPST  597
            T   C  VSF VP+  Q  G   E+ ++
Sbjct  558  TAGPCGLVSFAVPEDVQPTGLPEEQDAS  585


>emb|CAG11618.1|  unnamed protein product [Tetraodon nigroviridis]
Length=456

 Score =  588 bits (1517),  Expect = 2e-167, Method: Compositional matrix adjust.
 Identities = 289/454 (63%), Positives = 365/454 (80%), Gaps = 1/454 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            NPCC  PCQ++G+C   G D Y+CDCT TGY+GPNCT P   TW++ SL+PSP+  H+LL
Sbjct  3    NPCCSEPCQNRGVCTPIGKDSYECDCTLTGYAGPNCTTPEFLTWVKVSLKPSPNTVHYLL  62

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH + FW  VN  +F+R+ +MR VLT RS+LI SPPT+N+ +DY SWE++SN+SYYTR L
Sbjct  63   THFKGFWNIVNNISFLRDAIMRYVLTSRSHLIESPPTFNADYDYKSWEAYSNLSYYTRTL  122

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P V KDCPTPMG  GKK+LPD+++LA + L+RR+FIPDPQ T+LMFAFFAQHFTHQFFKT
Sbjct  123  PPVSKDCPTPMGVAGKKELPDSKVLAEKVLMRRQFIPDPQRTSLMFAFFAQHFTHQFFKT  182

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
              K GP FT A GHGVDLGHIYG +LERQ++LRLFKDGKL++QV++GE+YPP+V++  V 
Sbjct  183  DSKKGPAFTAAQGHGVDLGHIYGGDLERQHKLRLFKDGKLQHQVINGEVYPPTVKDVGVE  242

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M YP  IP   + AVG E FGL+PGLM+YAT+WLREHNRVCD+LK  HP W DE+LFQT+
Sbjct  243  MQYPPHIPESERFAVGHEAFGLVPGLMMYATIWLREHNRVCDVLKEVHPDWDDERLFQTS  302

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRIA EFN LYHWHPLMP
Sbjct  303  RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFKERFQYQNRIASEFNTLYHWHPLMP  362

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            DSF +  +EYSY++F+FN S++  +G+  LV++F++Q+AGR+ GGRN+   +L+V++  I
Sbjct  363  DSFHIEEKEYSYKEFVFNNSVVTRHGISHLVESFTKQLAGRVAGGRNVPKSLLYVSIKSI  422

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKE  485
              SR+MR Q  N YRKRF MKPY+SF+E+ G  E
Sbjct  423  ENSRQMRYQSLNAYRKRFSMKPYSSFEEMTGGTE  456


>ref|XP_002239723.1|  hypothetical protein BRAFLDRAFT_285765 [Branchiostoma floridae]
 gb|EEA40761.1|  hypothetical protein BRAFLDRAFT_285765 [Branchiostoma floridae]
Length=545

 GENE ID: 7253939 BRAFLDRAFT_285765 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  588 bits (1516),  Expect = 3e-167, Method: Compositional matrix adjust.
 Identities = 314/547 (57%), Positives = 396/547 (72%), Gaps = 6/547 (1%)

Query  39   PCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWF  98
            PCQ+ G+C+  G D Y CDCTRTGY G NC IP  WT ++ +L+PS   TH LLT+ +W 
Sbjct  2    PCQNMGVCMTEG-DSYSCDCTRTGYYGQNCDIPEFWTSIKVALKPSKKTTHHLLTNYKWL  60

Query  99   WEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKD  157
            W  VN   F+   +MR V  +RS  + SPP Y++ HDY SW+++++ SYYTR LP VP  
Sbjct  61   WNIVNRIPFLSNFIMRAVYKIRSATVDSPPMYHTGHDYTSWDTYADRSYYTRALPPVPPG  120

Query  158  CPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffktSGKMGP  217
            CPTPMGT G+K+LP  Q +A  FL RR+FIPD + TN++F F AQHFTHQFFKT  K G 
Sbjct  121  CPTPMGTAGRKELPSPQYIAETFLARRRFIPDKRRTNVLFNFMAQHFTHQFFKTDFKKGA  180

Query  218  GFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRG  277
            G T    HGVDL HIYG+ +ERQ+QLR F DGKLK+Q ++GE+YPPS+ +APV M YP  
Sbjct  181  GRTWG-DHGVDLSHIYGETVERQHQLRSFTDGKLKFQRVEGEVYPPSLADAPVHMIYPPY  239

Query  278  IPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG  337
            +P   + A+G E FGLLPGL +Y+T+WLREHNRVCD++K  HP W DE+LFQT RLIL G
Sbjct  240  VPEGKRFAIGHEFFGLLPGLFVYSTVWLREHNRVCDVMKELHPDWDDERLFQTARLILTG  299

Query  338  ETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVG  397
            ETI I+I EYVQ LSGY   L +DPELLF  QFQY+NRI +EFNHLYHWHPLMPD F + 
Sbjct  300  ETINIIINEYVQHLSGYNFDLFWDPELLFSDQFQYQNRIFVEFNHLYHWHPLMPDQFHIN  359

Query  398  SQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREM  457
               Y  +++LFNT ++  +G    VDA SRQIAG+I G +N+    L VAV+ I+  R +
Sbjct  360  GSTYGMKEYLFNTDLVFKHGFGTTVDAMSRQIAGQI-GPKNIGPVNLKVAVETIKHERNL  418

Query  458  RLQPFNEYRKRFGMKPYTSFQELV-GEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSI  516
            R+Q  N+YRKRFG+ PY +F EL  G+ EMA +LEE YGD+DA+E Y GL++E+  P S+
Sbjct  419  RMQGLNQYRKRFGIPPYKTFLELTGGDAEMADQLEEAYGDVDAVELYVGLMVEQPAPGSV  478

Query  517  FGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKT-CP  575
              E++IE+G PFS+KGLL NP+CSP++WKPSTFGGE GF +VKTATLK L C NT   C 
Sbjct  479  TSETIIEMGGPFSVKGLLSNPLCSPQWWKPSTFGGEAGFRMVKTATLKDLFCRNTAGPCG  538

Query  576  YVSFRVP  582
             VSF VP
Sbjct  539  LVSFAVP  545


>ref|XP_002212929.1|  hypothetical protein BRAFLDRAFT_75314 [Branchiostoma floridae]
 gb|EEA67748.1|  hypothetical protein BRAFLDRAFT_75314 [Branchiostoma floridae]
Length=598

 GENE ID: 7244311 BRAFLDRAFT_75314 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  560 bits (1442),  Expect = 9e-159, Method: Compositional matrix adjust.
 Identities = 283/566 (50%), Positives = 366/566 (64%), Gaps = 24/566 (4%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            N CC +PCQ+ G+C+R G D Y CDCT TGY G NC     WT L+ +LRPS      L 
Sbjct  20   NLCCSFPCQNMGVCMREG-DGYTCDCTGTGYYGQNCQTAEFWTMLKTALRPSDQTIDHLT  78

Query  93   THGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
             + +W W  +N T  +R  LMRL   +  + + SPP Y++ HDY +W+++S  SYYTR L
Sbjct  79   KNYKWLWHIINNTQALRNFLMRLFSKLYVDKVDSPPLYHTGHDYTTWDTYSARSYYTRAL  138

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VPKDCPTPMGTKG K+LP  + +A   L  +  +P    T    A             
Sbjct  139  PPVPKDCPTPMGTKGHKELPSPEYVAETSLGAQN-VPPGHETTHQHALRLHGAALHSSVL  197

Query  212  SGKMGPGFTKALGHG------VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSV  265
              ++  G    L         VD+ H+YG+ +ERQ QLR F+DGKLKYQ+++GE +PPS+
Sbjct  198  QNRLQEGTWSHLERPCGKFLFVDMSHVYGETVERQRQLRSFQDGKLKYQLVNGEAFPPSL  257

Query  266  EEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDE  325
            ++A V M YP  +P + + A+G E FGLLPGL ++AT+WLREHNRVCD++K  HP W DE
Sbjct  258  QDASVHMIYPPDVPEEKRFALGHEFFGLLPGLFVWATVWLREHNRVCDVMKDLHPDWDDE  317

Query  326  QLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYH  385
            +LFQT RLILIGETI IVI EYVQ L+G   QL +DPELLF  Q QY+N I +EFNHLYH
Sbjct  318  RLFQTARLILIGETINIVIGEYVQHLAGKNFQLFWDPELLFEEQLQYQNSIFVEFNHLYH  377

Query  386  WHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILH  445
            WH LMPD F +    Y  E++L+N  +++ +G+   VDA SRQIAGR             
Sbjct  378  WHVLMPDQFHINGTMYDMEEYLYNNDIVLKHGLNTTVDAMSRQIAGR-------------  424

Query  446  VAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL-VGEKEMAAELEELYGDIDALEFYP  504
            VAV+ I+  RE+R+QP N+YRKRFGM PY +F EL  G+ EMAA+LEE YGDIDA+E Y 
Sbjct  425  VAVETIKHERELRMQPLNQYRKRFGMPPYRTFLELTAGDTEMAAQLEEAYGDIDAVELYV  484

Query  505  GLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLK  564
            G  +E   P S+  E+++ +G+ FS KG+L NPICSP +WKPSTFGGEVGFN++KT TLK
Sbjct  485  GWAIENPMPGSVHSETIVRMGSTFSFKGMLANPICSPGWWKPSTFGGEVGFNLLKTTTLK  544

Query  565  KLVCLNTKT-CPYVSFRVPDASQDDG  589
             L C N    C  VSF VP+  +  G
Sbjct  545  DLFCRNMNGPCGLVSFTVPEDVEPTG  570


>gb|ACH87388.1|  cyclooxygenase-2 [Oplegnathus fasciatus]
Length=414

 Score =  550 bits (1416),  Expect = 1e-155, Method: Compositional matrix adjust.
 Identities = 256/380 (67%), Positives = 311/380 (81%), Gaps = 2/380 (0%)

Query  214  KMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMH  273
            K GP FT A GHGVDL HIYGD+LERQ++LRL KDGKLKYQ+LDGE+YPP+V+E  V MH
Sbjct  10   KKGPAFTVAKGHGVDLNHIYGDSLERQHKLRLLKDGKLKYQILDGEVYPPTVKEVGVDMH  69

Query  274  YPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRL  333
            YP  +P   + AVG E FGL+PGLM+YAT+WLREHNR CD+LK  HP W DE+LFQT+RL
Sbjct  70   YPPHVPDSHRFAVGHEAFGLVPGLMMYATIWLREHNRACDVLKEVHPDWDDERLFQTSRL  129

Query  334  ILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDS  393
            ILIGETIKIVIE+YVQ LSGY  +LKFDPELLF  +FQY+NRIA EFN LYHWHPLMPDS
Sbjct  130  ILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQRFQYQNRIASEFNTLYHWHPLMPDS  189

Query  394  FKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRE  453
            F V  Q+YSY+QF+FNTS++ ++G+  LV++F+ QIAGR+ GGRN+   I++VA+  I  
Sbjct  190  FHVEEQDYSYKQFVFNTSVVTEHGISNLVESFTNQIAGRVAGGRNVPGPIMYVAIKSIEN  249

Query  454  SREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHP  513
            SR+MR Q  N YRKRF MKPY+SF+++ GEKEMAA LEE+YG IDA+E YPGLL+EK  P
Sbjct  250  SRQMRYQSLNAYRKRFSMKPYSSFEDMTGEKEMAAVLEEMYGHIDAVELYPGLLVEKPRP  309

Query  514  NSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKT  573
            N+IFGE+M+E+GAPFSLKGL+GNPICSPEYWKPSTFGG VGF+IV TA+L++LVC N + 
Sbjct  310  NAIFGETMVEMGAPFSLKGLMGNPICSPEYWKPSTFGGSVGFDIVNTASLQRLVCNNVRG  369

Query  574  -CPYVSFRVPDASQDDGPAV  592
             CP  SF VPD  +D G  +
Sbjct  370  PCPVASFHVPDV-KDTGSMI  388


>ref|XP_002123273.1|  PREDICTED: similar to prostaglandin-endoperoxide synthase 2b 
[Ciona intestinalis]
Length=623

 GENE ID: 100183175 LOC100183175 | similar to prostaglandin-endoperoxide
synthase 2b [Ciona intestinalis]

 Score =  513 bits (1321),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 269/551 (48%), Positives = 361/551 (65%), Gaps = 4/551 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            +PCC +PC+H  IC     D Y+CDCT TG+ G NC      T++ +  RPS S  H  +
Sbjct  24   DPCCAFPCKHSAICTTLK-DDYECDCTGTGFYGRNCEYGYFSTYVTDLFRPSRSTLHHYM  82

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            T+    W+ VN  +++++ LM +VL +R+N +  P  Y     Y +W+S+ N + Y R L
Sbjct  83   TNYSLLWKLVNNISWLQKKLMAVVLKIRTNYVYEPSPYVGMDSYPTWDSYINKTVYARTL  142

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P +P+DCPTPMGTKG K LPD ++L      R KF P P  TN+ FAFFAQHFTHQFFKT
Sbjct  143  PPIPQDCPTPMGTKGPKTLPDIKVLRSLLFQRNKFEPCPMRTNVFFAFFAQHFTHQFFKT  202

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
            +   G  F     H VDL H+YG  ++RQ++LR   DGKLK    +GE++PP  E A V 
Sbjct  203  NTIKGMPFQWG-EHSVDLSHVYGHTIQRQHELRSHIDGKLKVFETNGEVFPPLTESANVT  261

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M   + +  + + A+G   FG  P   + ATLWLREHNRVCD+LK  HP W DE+LFQT 
Sbjct  262  MSGEKLMRGR-KFAIGHPGFGAFPSFFVIATLWLREHNRVCDILKDLHPDWDDERLFQTA  320

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RLIL GET+KI++E+YVQ +SG+  QL +DPE+L    F Y N+I  EF+ LYHWH LMP
Sbjct  321  RLILTGETLKIIVEDYVQHVSGFHFQLSYDPEILHKSTFSYNNQIHAEFHILYHWHMLMP  380

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D  ++G   Y  ++ LFN   +V+ G+E ++   S Q AG++ GGRN    ++ V    +
Sbjct  381  DFIELGEHVYPLKELLFNVDPVVEIGMETVLKQLSNQFAGKVVGGRNQGPELVAVVELAL  440

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
            +++R+MR+  FN+YR+RFGMKPYTSF+EL GE E+AA L  LY DIDALE + G  +E  
Sbjct  441  KQTRQMRMCSFNKYRERFGMKPYTSFEELTGETEVAALLRNLYYDIDALELFVGYFVEHR  500

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
                + G +M+E+GAP+SLKG+ GNPI SP +WKPSTFGGEVGFNI+KT  LK  +C N 
Sbjct  501  RNRQVLGATMLEMGAPYSLKGVFGNPIGSPAWWKPSTFGGEVGFNIIKTTNLKNFICRNV  560

Query  572  KTCPYVSFRVP  582
            K CP +SF+VP
Sbjct  561  KGCPDISFKVP  571


>ref|XP_002127674.1|  PREDICTED: similar to prostaglandin-endoperoxide synthase 2 [Ciona 
intestinalis]
Length=653

 GENE ID: 100183010 LOC100183010 | similar to prostaglandin-endoperoxide
synthase 2 [Ciona intestinalis] (10 or fewer PubMed links)

 Score =  501 bits (1290),  Expect = 4e-141, Method: Compositional matrix adjust.
 Identities = 254/554 (45%), Positives = 362/554 (65%), Gaps = 2/554 (0%)

Query  33   NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL  92
            +PCC +PCQHQ +C    +  YQCDCT TGY G  C  P L T ++  ++PS S TH++L
Sbjct  53   DPCCSFPCQHQSVCTSPDMISYQCDCTGTGYYGDECQHPYLSTRIKKWIKPSKSTTHYIL  112

Query  93   THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            TH +W W  VN  +++R+ LM+ VL +R + +  P  Y     Y SW ++ N + Y R L
Sbjct  113  THFKWVWTIVNNVSWLRKTLMKAVLAMRVSSVTEPSPYRGLSSYPSWSAYINDTMYVRTL  172

Query  152  PSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffkt  211
            P VP +CPTPMG KGK +LP+  +L  +F  RR F P PQ T+++F FFAQHFTH FFKT
Sbjct  173  PPVPTNCPTPMGVKGKPELPEISVLLEKFFKRRTFQPCPQRTSVLFPFFAQHFTHMFFKT  232

Query  212  SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL  271
                G  +       VDL  IYG   +RQ++LR   +GKLK  ++DG  +PP   +    
Sbjct  233  DPMKGMPYQWG-DQLVDLSQIYGHGEKRQHELRSHVNGKLKVSLVDGHEFPPLSNQTTAN  291

Query  272  MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT  331
            M     +P + Q   G + F L+P  ++++T+WLREHNR+CDL+K E+P W DE++FQT 
Sbjct  292  MSNINLLPQEYQFVFGHQGFSLMPTFLIWSTIWLREHNRICDLIKEENPAWDDERIFQTA  351

Query  332  RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
            RL+L GETIK+VIE+YVQ LSG+  +L +DPEL+ G    + N+I +EF  LYHWH LMP
Sbjct  352  RLVLTGETIKVVIEDYVQHLSGFHYKLLYDPELVQGGSHSFHNQIHVEFQLLYHWHALMP  411

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI  451
            D  +   + Y+ ++ LFN   +V  G++  ++  S Q AG++ GG+      LHVA   I
Sbjct  412  DQIEFNGKSYTMKRLLFNPEPVVKGGLKRTIEDLSNQWAGQVAGGKTQGAATLHVAGLAI  471

Query  452  RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC  511
            +  R++R+Q FN Y+++F MK YT+FQEL GE+EMAAEL++LYGDIDA+E+Y G++LEK 
Sbjct  472  KNGRDLRMQSFNAYKEKFEMKKYTTFQELTGEEEMAAELQKLYGDIDAVEYYIGIMLEKR  531

Query  512  HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
                +FGE++ E+G+P+SLKGL  NPI   ++WKPSTFGG+   +++K   L+ L+C   
Sbjct  532  RSPQLFGETLTEMGSPYSLKGLYSNPINHKDWWKPSTFGGQKIMDVIKNTNLQSLICRTV  591

Query  572  KTCPYVSFRVPDAS  585
            + CP+ SF VPD +
Sbjct  592  EGCPHASFTVPDGA  605


>ref|XP_002205720.1|  hypothetical protein BRAFLDRAFT_68307 [Branchiostoma floridae]
 gb|EEA74689.1|  hypothetical protein BRAFLDRAFT_68307 [Branchiostoma floridae]
Length=1244

 GENE ID: 7223545 BRAFLDRAFT_68307 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  498 bits (1281),  Expect = 5e-140, Method: Compositional matrix adjust.
 Identities = 284/584 (48%), Positives = 365/584 (62%), Gaps = 70/584 (11%)

Query  41    QHQGICVRFGLDRYQCDCTRTGYSGP-------------------------------NCT  69
             ++ G+C+R G   Y CDCTRTGY G                                +CT
Sbjct  659   RNMGVCMREG-GGYTCDCTRTGYYGQTRTAKYCNSHHIYISSVKSYEMHQADRCMSLSCT  717

Query  70    IPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNAT-FIREMLMRLVLTVRSNLIPSPPT  128
                L T L  +L+PS      LL + +W W  +N T  +R  LMRL+  +    + SPP 
Sbjct  718   AE-LLTALGAALKPSDEMIDHLLFNYKWLWHIINNTQSLRNFLMRLLSKLSVGQVDSPPL  776

Query  129   YNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIP  188
             Y++ HDY SW+++S  SYYTR LP VP DCPTPMGTKG K+LP  + LA  FL RR F+P
Sbjct  777   YHTGHDYTSWDTYSARSYYTRALPPVPADCPTPMGTKGPKELPSPEYLAETFLARRTFLP  836

Query  189   DPQG-TNLMfaffaqhfthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFK  247
             D +  TN++F F AQHFTHQFFKT  K GPG T +  H VD+ H+YG+  ERQ+QLR F+
Sbjct  837   DTRRRTNVLFGFMAQHFTHQFFKTDFKKGPGHTWS-DHAVDMSHVYGETTERQHQLRSFQ  895

Query  248   DGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLRE  307
             DGKLKYQ++DGE++PPS+++APV M YP  +P   + A+G E FG LPGL ++AT+WLRE
Sbjct  896   DGKLKYQLVDGEVFPPSLQDAPVHMIYPPNVPEDKRFALGHEFFGHLPGLFVWATVWLRE  955

Query  308   HNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFG  367
             HNRVCD++K  HP W DE+LFQT RLILIGETIKIVIEEYVQ L+G   QL +DPELLF 
Sbjct  956   HNRVCDVMKKVHPDWDDERLFQTARLILIGETIKIVIEEYVQHLAGNNFQLVWDPELLFE  1015

Query  368   VQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSR  427
              + QY+NRI++EFNHLYHWH LMPD F +    Y+ E +LFN  +++ +G+ A VDA SR
Sbjct  1016  ERLQYQNRISVEFNHLYHWHMLMPDHFDINGTMYTMEDYLFNNDIVLKHGLNATVDAMSR  1075

Query  428   QIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMA  487
             QIAGR+        ++ H   ++IR                             G+ EMA
Sbjct  1076  QIAGRVSAT-----YLGHCIYNIIRAP---------------------------GDAEMA  1103

Query  488   AELEELYGDIDALEFYPGLLLEKCHP-NSIFGESMIEIGAPFSLKGLLGNPICSPEYWKP  546
             A+LEE YGDIDA+E Y G  +E   P  ++  E  + +G+ FS  G+L NPICSP +WKP
Sbjct  1104  AQLEEAYGDIDAVELYVGWAMENPMPAGNVLSEMFVRMGSTFSFTGMLSNPICSPGWWKP  1163

Query  547   STFGGEVGFNIVKTATLKKLVCLNTKT-CPYVSFRVPDASQDDG  589
             STFGGEVGFN++KT TLK L C N    C  VSF VP+  +  G
Sbjct  1164  STFGGEVGFNLLKTTTLKDLFCRNMNGPCGLVSFSVPEDVEPTG  1207


>gb|ACH73269.1|  cyclooxygenase [Petromyzon marinus]
Length=286

 Score =  386 bits (992),  Expect = 2e-106, Method: Compositional matrix adjust.
 Identities = 178/276 (64%), Positives = 216/276 (78%), Gaps = 0/276 (0%)

Query  216  GPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYP  275
            GP FT+ALGHGVDL HIYG  LERQ+QLRLFKDGKLK+Q++DGE YPP V +APV M YP
Sbjct  11   GPAFTRALGHGVDLNHIYGGTLERQHQLRLFKDGKLKFQMIDGEAYPPVVRDAPVHMVYP  70

Query  276  RGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLIL  335
              +P   + AVG EV+GLLPGL++YAT+WLREHNRVCD+L A HP W DE+LFQT RLIL
Sbjct  71   EHVPASLRFAVGHEVYGLLPGLLVYATVWLREHNRVCDVLHARHPRWDDERLFQTARLIL  130

Query  336  IGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFK  395
             GET+KIVIEEYVQ LSGY   LKFDP LLFGV FQY NR+++EFNHLYHWHPLMPDS  
Sbjct  131  TGETMKIVIEEYVQHLSGYNFHLKFDPTLLFGVNFQYSNRMSLEFNHLYHWHPLMPDSLL  190

Query  396  VGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESR  455
            +  + YSY++FLFN  +L D  +  LV +F RQ AG + GGRN++ ++LHVA  +I   R
Sbjct  191  IDGRNYSYDEFLFNPGLLADKKLMPLVRSFMRQRAGTVSGGRNINKNLLHVATSIIEHGR  250

Query  456  EMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELE  491
             +RLQ  N+YR RF M+P+TSF EL G++ MAAE+E
Sbjct  251  TLRLQSLNQYRHRFNMRPFTSFLELTGDEAMAAEME  286


>emb|CAG08128.1|  unnamed protein product [Tetraodon nigroviridis]
Length=1023

 Score =  331 bits (848),  Expect = 7e-90, Method: Compositional matrix adjust.
 Identities = 156/230 (67%), Positives = 185/230 (80%), Gaps = 0/230 (0%)

Query  337  GETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKV  396
            GETIKI+IEEYVQQLSGYF +LKFDP LLF  QFQY NRIA+EF+HLYHWH L+PDS+ +
Sbjct  335  GETIKIIIEEYVQQLSGYFFKLKFDPTLLFKEQFQYSNRIAVEFDHLYHWHSLLPDSYLI  394

Query  397  GSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESRE  456
               E S   F+FN S+L +YGVE +VD+FSRQIAG+IGGG+N    I+ V   ++   RE
Sbjct  395  DGDEISATGFVFNGSVLANYGVEKMVDSFSRQIAGQIGGGQNFHESIIRVIRSLLHHGRE  454

Query  457  MRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSI  516
            +RLQPFNEYRK+F  KPY SF EL   +E+A  LEE YGDIDALEF+PG++LEK  P  I
Sbjct  455  VRLQPFNEYRKKFDQKPYESFSELTDNEEIAKGLEEAYGDIDALEFFPGIMLEKTSPGHI  514

Query  517  FGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKL  566
            FGESM ++GAPFSLKGL+GN ICSPEYWKPSTFGGE GFNI+KTATL+KL
Sbjct  515  FGESMFQMGAPFSLKGLMGNAICSPEYWKPSTFGGETGFNIIKTATLEKL  564


 Score =  282 bits (722),  Expect = 3e-75, Method: Compositional matrix adjust.
 Identities = 140/209 (66%), Positives = 168/209 (80%), Gaps = 1/209 (0%)

Query  227   VDLGHIYGDNLERQYQLRLFKDGKLKYQ-VLDGEMYPPSVEEAPVLMHYPRGIPPQSQMA  285
             VD  +IYGDNL RQ QLRL KDGKLKYQ +++GEMYPP+V +  V M YP  +PP+ ++ 
Sbjct  815   VDGSNIYGDNLMRQLQLRLLKDGKLKYQQLVNGEMYPPTVNKVSVYMMYPETVPPEQRLV  874

Query  286   VGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIE  345
             +G E+FGL+PGL LYATLWLREHNRVCD+LK EHPTW DEQLFQT RLI+IGETIKI+IE
Sbjct  875   IGHELFGLVPGLSLYATLWLREHNRVCDILKEEHPTWDDEQLFQTARLIVIGETIKIIIE  934

Query  346   EYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQ  405
             +YVQ LSGY  +LKFDP LLF  QFQY NRIA+EF HLYHWH LMPDSF +   + S  +
Sbjct  935   DYVQHLSGYLFKLKFDPSLLFKEQFQYSNRIALEFVHLYHWHSLMPDSFLIDGDDISLPE  994

Query  406   FLFNTSMLVDYGVEALVDAFSRQIAGRIG  434
             FL+N+S+L  YGVE LVD+FSRQ AG++ 
Sbjct  995   FLYNSSILTHYGVEKLVDSFSRQRAGQVA  1023


 Score =  201 bits (511),  Expect = 9e-51, Method: Compositional matrix adjust.
 Identities = 83/136 (61%), Positives = 105/136 (77%), Gaps = 0/136 (0%)

Query  32   VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFL  91
            VNPCCYYPCQH G+CVR+G D+YQCDCT TG+ G NCT+P  WT +   L+PSP   HF+
Sbjct  593  VNPCCYYPCQHAGVCVRYGTDQYQCDCTGTGFYGDNCTVPEFWTNIYVMLKPSPPLVHFI  652

Query  92   LTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL  151
            L H +WFW+FVN +F++++ MR VLTVR  LIP  PTYN+ + Y++WES+ N SYYTRIL
Sbjct  653  LKHFQWFWDFVNNSFLQDVFMRFVLTVRIKLIPIIPTYNTKYGYLNWESYYNTSYYTRIL  712

Query  152  PSVPKDCPTPMGTKGK  167
            P VP+DCP PMG  G+
Sbjct  713  PPVPEDCPLPMGAIGE  728


 Score =  127 bits (320),  Expect = 1e-28, Method: Compositional matrix adjust.
 Identities = 52/96 (54%), Positives = 69/96 (71%), Gaps = 0/96 (0%)

Query  27   GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPS  86
            G  + VNPCCYYPCQ++G+CVR+G D+Y+CDCTRTGYSG NCT PG W  +   L+PSP 
Sbjct  25   GDGSAVNPCCYYPCQNRGVCVRYGTDQYKCDCTRTGYSGVNCTDPGFWAKVHTMLKPSPQ  84

Query  87   FTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNL  122
               ++L H   FW++VN + +R+  MR+VLT R  L
Sbjct  85   VQDYILRHFEKFWDYVNNSPLRDTFMRIVLTARIEL  120


>emb|CAM14110.1|  prostaglandin-endoperoxide synthase 1 [Danio rerio]
Length=257

 Score =  307 bits (787),  Expect = 1e-82, Method: Compositional matrix adjust.
 Identities = 162/231 (70%), Positives = 193/231 (83%), Gaps = 0/231 (0%)

Query  26   PGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSP  85
            P +    NPCCYYPCQ+QGICVR+GLDRY+CDCTRTGY G NCTIP LWT +   L+PSP
Sbjct  27   PTSSNTANPCCYYPCQNQGICVRYGLDRYECDCTRTGYYGENCTIPELWTRVYRLLKPSP  86

Query  86   SFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVS  145
            +  H++LTH  W W+ +N +F+R+ LMR VLTVR+NLIPSPPTYNS +DY++WE++SN++
Sbjct  87   NVVHYILTHFDWLWDLINRSFLRDWLMRKVLTVRANLIPSPPTYNSRYDYLNWEAYSNIT  146

Query  146  YYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhft  205
            YYTRILP VP DCPTPMGTKGK +LPD +LL  +F+LRR F  DPQGTNLMFAFFAQHFT
Sbjct  147  YYTRILPPVPNDCPTPMGTKGKIKLPDPKLLVEKFMLRRNFRLDPQGTNLMFAFFAQHFT  206

Query  206  hqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVL  256
            HQFFKT  ++G GFTK LGHGVD GHIYGD+L+RQ +LRL KDGKLKYQVL
Sbjct  207  HQFFKTHNRVGLGFTKGLGHGVDAGHIYGDSLDRQLELRLHKDGKLKYQVL  257


>gb|ACL35628.1|  cyclooxygenase-2 [Hippocampus kuda]
Length=204

 Score =  241 bits (615),  Expect = 8e-63, Method: Compositional matrix adjust.
 Identities = 135/204 (66%), Positives = 165/204 (80%), Gaps = 1/204 (0%)

Query  99   WEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKD  157
            W  +N  +F+R  +M+ VLT RS++I SPPTYN+ + Y SWE++SN+SYYTR LP VP+D
Sbjct  1    WNIINNISFLRNAIMKYVLTSRSHMIDSPPTYNADYHYKSWEAYSNLSYYTRALPPVPQD  60

Query  158  CPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLMfaffaqhfthqffktSGKMGP  217
            CPTPMG  GKK+LPD +LLA + L RRKFIPDPQGT+LMFAFFAQHFTHQFFKT  K GP
Sbjct  61   CPTPMGVVGKKELPDVKLLAEKLLTRRKFIPDPQGTSLMFAFFAQHFTHQFFKTDMKRGP  120

Query  218  GFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRG  277
             FT A GHGVDL H+YGD+LE+Q++LRLFKDGKL+YQ LDGEMYPP+V++  V MHYP  
Sbjct  121  AFTMAKGHGVDLSHVYGDSLEKQHKLRLFKDGKLRYQTLDGEMYPPTVKDVGVDMHYPPH  180

Query  278  IPPQSQMAVGQEVFGLLPGLMLYA  301
            +P   + AVG E FGL+PGLM+YA
Sbjct  181  VPDSHRFAVGHEAFGLVPGLMMYA  204


>gb|ACH73270.1|  cyclooxygenase-c [Branchiostoma lanceolatum]
Length=177

 Score =  222 bits (566),  Expect = 4e-57, Method: Compositional matrix adjust.
 Identities = 108/170 (63%), Positives = 130/170 (76%), Gaps = 1/170 (0%)

Query  214  KMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMH  273
            K G G T    HGVDL HIYG+ +ERQ+QLR F DGKLK+Q ++GE+YPPS+ +APV M 
Sbjct  9    KKGAGRTWG-DHGVDLSHIYGETVERQHQLRSFTDGKLKFQRVEGEVYPPSLADAPVHMI  67

Query  274  YPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRL  333
            YP  +P   + A+G E FGLLPGL +Y+T+WLREHNRVCD++K  HP W DE+LFQT RL
Sbjct  68   YPPYVPEGKRFAIGHEFFGLLPGLFVYSTVWLREHNRVCDVMKELHPDWDDERLFQTARL  127

Query  334  ILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            IL GETI I+I EYVQ LSGY   L +DPELLF  QFQY+NRI +EFNHL
Sbjct  128  ILTGETINIIINEYVQHLSGYNFDLFWDPELLFSDQFQYQNRIFVEFNHL  177


>gb|ACH73271.1|  cyclooxygenase-d [Branchiostoma lanceolatum]
Length=177

 Score =  214 bits (544),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 103/170 (60%), Positives = 130/170 (76%), Gaps = 1/170 (0%)

Query  214  KMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMH  273
            K GPG T +  H VD+ H+YG+ +ERQ QLR F+DGKLKYQ++DGE +PPS+++A V M 
Sbjct  9    KKGPGRTWS-DHAVDMSHVYGETVERQRQLRSFQDGKLKYQLVDGEAFPPSLQDASVHMI  67

Query  274  YPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRL  333
            YP  +P + + A+G E FGLLPGL ++AT+WLREHNRVCD++K  HP W DE+L+QT RL
Sbjct  68   YPPDVPEKKRFALGHEFFGLLPGLFVWATVWLREHNRVCDVMKDLHPDWDDERLYQTARL  127

Query  334  ILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHL  383
            ILI ETI IVI EYVQ L+G   QL +DPELLF  Q QY+N I +EFNHL
Sbjct  128  ILISETINIVIGEYVQHLAGKNFQLFWDPELLFEEQXQYQNSIFVEFNHL  177


>gb|ABU98644.1|  cyclooxygenase-2 [Epinephelus coioides]
Length=108

 Score =  139 bits (350),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 63/92 (68%), Positives = 76/92 (82%), Gaps = 0/92 (0%)

Query  214  KMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMH  273
            + GP FT A GHGVDLGHIYGDNLERQ++LRLFKDGKLKYQ++DGE+YPP+V+E  V MH
Sbjct  17   REGPAFTVAKGHGVDLGHIYGDNLERQHKLRLFKDGKLKYQIIDGEVYPPTVKEVGVDMH  76

Query  274  YPRGIPPQSQMAVGQEVFGLLPGLMLYATLWL  305
            YP  +P   + AVG E FGL+PGLM+YA +WL
Sbjct  77   YPPHVPDSDRFAVGHEAFGLVPGLMMYAPIWL  108


>ref|XP_002245690.1|  hypothetical protein BRAFLDRAFT_153094 [Branchiostoma floridae]
 gb|EEA34811.1|  hypothetical protein BRAFLDRAFT_153094 [Branchiostoma floridae]
Length=104

 GENE ID: 7233589 BRAFLDRAFT_153094 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  137 bits (345),  Expect = 2e-31, Method: Compositional matrix adjust.
 Identities = 64/104 (61%), Positives = 82/104 (78%), Gaps = 1/104 (0%)

Query  469  FGMKPYTSFQELVG-EKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAP  527
            FG+ PY +F EL G + EMA +LEE YGD+DA+E Y GL++E+  P S+  E++IE+G P
Sbjct  1    FGIPPYKTFLELTGGDAEMADQLEEAYGDVDAVELYVGLMVEQPAPGSVTSETIIEMGGP  60

Query  528  FSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
            FS+KGLL NP+CSP++WKPSTFGGE GF +VKTATLK L C NT
Sbjct  61   FSVKGLLSNPLCSPQWWKPSTFGGEAGFRMVKTATLKNLFCRNT  104


>gb|AAQ22672.1|  cyclo-oxygenase-2 [Dicentrarchus labrax]
Length=108

 Score =  136 bits (343),  Expect = 3e-31, Method: Compositional matrix adjust.
 Identities = 62/92 (67%), Positives = 74/92 (80%), Gaps = 0/92 (0%)

Query  214  KMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMH  273
            K GP FT A GHGVDL HIYGD LERQ++LRLFKDGKLKYQ+++GEMYPP+V+E    MH
Sbjct  17   KKGPAFTVAKGHGVDLSHIYGDKLERQHKLRLFKDGKLKYQMVNGEMYPPTVKEVGAEMH  76

Query  274  YPRGIPPQSQMAVGQEVFGLLPGLMLYATLWL  305
            YP  +P   + AVG E FGL+PGLM+YAT+WL
Sbjct  77   YPPHVPEAHRFAVGHEAFGLVPGLMMYATIWL  108


>gb|AAW31868.1|  cyclooxygenase 2 [Salmo salar]
Length=129

 GENE ID: 100136456 cox-2 | cyclooxygenase 2 [Salmo salar]
(10 or fewer PubMed links)

 Score =  128 bits (321),  Expect = 1e-28, Method: Compositional matrix adjust.
 Identities = 63/107 (58%), Positives = 83/107 (77%), Gaps = 1/107 (0%)

Query  91   LLTHGRWFWEFVNA-TFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTR  149
            +LTH +  W  +N  TF+R  +M  VLT RS+L+ SPPTYN+ + Y SWE++SN+SYYTR
Sbjct  1    ILTHYKGLWNVINKITFVRNAIMSYVLTSRSHLVDSPPTYNADYGYKSWEAYSNLSYYTR  60

Query  150  ILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQGTNLM  196
             LP +PKDCPTPMGT G+  LPDA+L+  + LLR++FIPDPQG+NLM
Sbjct  61   TLPPLPKDCPTPMGTAGRAVLPDAKLVVEKVLLRKRFIPDPQGSNLM  107


>ref|XP_002237803.1|  hypothetical protein BRAFLDRAFT_162714 [Branchiostoma floridae]
 gb|EEA42689.1|  hypothetical protein BRAFLDRAFT_162714 [Branchiostoma floridae]
Length=104

 GENE ID: 7252945 BRAFLDRAFT_162714 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  125 bits (314),  Expect = 6e-28, Method: Composition-based stats.
 Identities = 60/104 (57%), Positives = 74/104 (71%), Gaps = 2/104 (1%)

Query  469  FGMKPYTSFQELV-GEKEMAAELEELYGDIDALEFYPGLLLEKCHP-NSIFGESMIEIGA  526
            FGM PY +F EL  G+ EMAA+LEE YGDIDA+E Y G  +E   P  ++  E  + +G+
Sbjct  1    FGMAPYRTFLELTAGDAEMAAQLEEAYGDIDAVELYVGWAMENPMPAGNVLSEMFVRMGS  60

Query  527  PFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
             FS  G+L NPICSP +WKPSTFGGEVGFN++KT TLK L C N
Sbjct  61   TFSFTGMLSNPICSPGWWKPSTFGGEVGFNLLKTTTLKDLFCRN  104


>emb|CAC59825.1|  cyclooxygenase-1 [Oncorhynchus mykiss]
Length=92

 Score =  124 bits (312),  Expect = 1e-27, Method: Composition-based stats.
 Identities = 57/83 (68%), Positives = 67/83 (80%), Gaps = 0/83 (0%)

Query  215  MGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHY  274
            MG GFT+ALGHGVD G++YGDNL RQ  LRL KDGK+KYQV+ GE+YPP+V EA V M Y
Sbjct  10   MGLGFTRALGHGVDAGNVYGDNLVRQLNLRLLKDGKMKYQVVKGEVYPPTVAEAAVNMRY  69

Query  275  PRGIPPQSQMAVGQEVFGLLPGL  297
            P+  P   +MA+GQEVFGLLPGL
Sbjct  70   PQETPVGQRMAIGQEVFGLLPGL  92


>ref|XP_002212444.1|  hypothetical protein BRAFLDRAFT_161760 [Branchiostoma floridae]
 gb|EEA67904.1|  hypothetical protein BRAFLDRAFT_161760 [Branchiostoma floridae]
Length=126

 GENE ID: 7236462 BRAFLDRAFT_161760 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  114 bits (285),  Expect = 1e-24, Method: Compositional matrix adjust.
 Identities = 77/127 (60%), Positives = 98/127 (77%), Gaps = 2/127 (1%)

Query  145  SYYTRILPSVPKDCPTPMGTKGKKQLPDAQllarrfllrrKFIPDPQG-TNLMfaffaqh  203
            SYYTR LP VP+DCPTPMGTKG K+LP  + LA+ FL R  F+PD +  TN++F F AQH
Sbjct  1    SYYTRALPPVPEDCPTPMGTKGHKELPSPEYLAQTFLARTTFLPDTRRRTNVLFGFMAQH  60

Query  204  fthqffktSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPP  263
            FTHQFFKT  K GPG T +  H VD+  +YG+ + RQ QLR FKDGKLK+Q++DGE++PP
Sbjct  61   FTHQFFKTDFKKGPGRTWS-DHAVDMSQVYGETVGRQQQLRTFKDGKLKHQLVDGEVFPP  119

Query  264  SVEEAPV  270
            S+++APV
Sbjct  120  SLQDAPV  126


>ref|XP_002211718.1|  hypothetical protein BRAFLDRAFT_74147 [Branchiostoma floridae]
 gb|EEA68628.1|  hypothetical protein BRAFLDRAFT_74147 [Branchiostoma floridae]
Length=945

 GENE ID: 7236252 BRAFLDRAFT_74147 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 95.1 bits (235),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 99/406 (24%), Positives = 173/406 (42%), Gaps = 79/406 (19%)

Query  219  FTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGI  278
            F  A  H  D   +YG + E Q  LR  KDGKLK            V  + +       I
Sbjct  525  FRNANTHWWDASQLYGSDAETQLALREMKDGKLK------------VTSSGL-------I  565

Query  279  PPQSQMAVGQEVF--GLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI  336
            P   +  V +  F      GL +   L+ REHN +CD++KA++P   D++LF   RL+  
Sbjct  566  PLDKKTGVEKTGFSNNWWVGLSMLHNLFTREHNVICDVMKAKYPDMTDQELFDKARLVNA  625

Query  337  GETIKIVIEEYVQQL-----------SGYF-----------LQLKFDPE--LLFGVQFQY  372
                K+   E+   L           S +F           L  +F PE  +L G+    
Sbjct  626  AVMSKLHTVEWTPALLYNDILDVGMNSNWFGLLSQLGDFGNLLKRFLPENYVLTGIPGSA  685

Query  373  RN------RIAMEFNHLYHWHPLMPD--------SFKVGSQEYSYEQFLFNTSMLV--DY  416
            ++       +  EF  +Y  H ++PD        S K   + Y+ +  LF+ +  V    
Sbjct  686  KDLHGVPYSLTEEFTAVYRMHSILPDIIHLQDIKSAKRTGKTYALKDILFSKASKVVEKQ  745

Query  417  GVEALVDAFSRQIAGRI------GGGRNMD-------HHILHVAVDVIRESREMRLQPFN  463
            G+E L   F  +  G +         R++         ++    VDV+R+ RE  +  +N
Sbjct  746  GMENLFYTFGVENPGALVLHNYPNTIRDLQLPETQNAEYVDMATVDVLRD-RERGVPRYN  804

Query  464  EYRKRFGMKPYTSFQELVGEKEMAAELEELY-GDIDALEFYPGLLLEKCHPNSI-FGESM  521
            E R+   M P  +F+++  + ++A ELEE+Y GD++ ++   G + E   P    F ++ 
Sbjct  805  ELRRHLNMAPAETFRDITDDPKVAEELEEMYEGDVEMVDLLVGCMAESPRPTGFAFSDTA  864

Query  522  IEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLV  567
              +    + + L  +   + +Y+  +T+  E G + V+ AT+  ++
Sbjct  865  FRLFLLMATRRLQADRFYT-DYYNSATYTQE-GLDWVENATMSSVL  908


>ref|XP_002226612.1|  hypothetical protein BRAFLDRAFT_89035 [Branchiostoma floridae]
 gb|EEA53914.1|  hypothetical protein BRAFLDRAFT_89035 [Branchiostoma floridae]
Length=1509

 GENE ID: 7206885 BRAFLDRAFT_89035 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 93.6 bits (231),  Expect = 3e-18, Method: Compositional matrix adjust.
 Identities = 100/406 (24%), Positives = 170/406 (41%), Gaps = 79/406 (19%)

Query  219   FTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGI  278
             F  A  H  D   +YG + E Q  LR  KDGKLK  V    M                 I
Sbjct  915   FRNANTHWWDASQLYGSDAETQLALREMKDGKLK--VTSSGM-----------------I  955

Query  279   PPQSQMAVGQEVF--GLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI  336
             P   +  V +  F      GL +   L+ REHN +CD++KA++P   D++LF   RL+  
Sbjct  956   PLDKKTGVEKTGFSNNWWVGLSMLHNLFTREHNVICDVIKAKYPDMTDQELFDKARLVNA  1015

Query  337   GETIKIVIEEY---------------------VQQLSGYFLQLK-FDPE--LLFGVQFQY  372
                 K+   E+                     + QL G+   LK   PE  +L G+    
Sbjct  1016  AVMSKLHTVEWTPALLYNDILDVGMNSNWFGLLSQLGGFGNLLKRVLPEHYVLTGIPGSV  1075

Query  373   RN------RIAMEFNHLYHWHPLMPD--------SFKVGSQEYSYEQFLFNTSMLV--DY  416
             +        I  EF  +Y  H ++PD        S K   + Y+ +  LF+ +  V    
Sbjct  1076  KELHGVPYSITEEFTAVYRMHSILPDVIHLQDMKSTKRTGKTYALKDTLFSKASKVVEKQ  1135

Query  417   GVEALVDAFSRQIAGRI------GGGRNMD-------HHILHVAVDVIRESREMRLQPFN  463
             G+  L   F  +  G +         R++         ++    VDV+R+ RE  +  +N
Sbjct  1136  GMGNLFYTFGVENPGALVLHNYPNTIRDLQLPETQNAEYVDMATVDVLRD-RERGVPRYN  1194

Query  464   EYRKRFGMKPYTSFQELVGEKEMAAELEELY-GDIDALEFYPGLLLEKCHPNSI-FGESM  521
             E R+   M P  +F+++  + ++A ELEE+Y GD++ ++   G + E   P    F ++ 
Sbjct  1195  ELRRHLNMAPAETFRDITDDPKVAEELEEMYEGDVEMVDLLVGCMAESPRPTGFAFSDTA  1254

Query  522   IEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLV  567
               +    + + L  +   + +Y+  +T+  E G + V+ AT+  ++
Sbjct  1255  FRLFLLMATRRLQADRFYT-DYYNSATYTQE-GLDWVENATMSSVL  1298


>ref|XP_002226578.1|  hypothetical protein BRAFLDRAFT_125407 [Branchiostoma floridae]
 gb|EEA53880.1|  hypothetical protein BRAFLDRAFT_125407 [Branchiostoma floridae]
Length=601

 GENE ID: 7205874 BRAFLDRAFT_125407 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 93.2 bits (230),  Expect = 4e-18, Method: Compositional matrix adjust.
 Identities = 100/408 (24%), Positives = 171/408 (41%), Gaps = 81/408 (19%)

Query  219  FTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGI  278
            F  A  H  D   +YG + E Q  LR  KDGKLK  V    M                 I
Sbjct  179  FRNANTHWWDASQLYGSDAETQLALREMKDGKLK--VTSSGM-----------------I  219

Query  279  PPQSQMAVGQEVF--GLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI  336
            P   +  V +  F      GL +   L+ REHN +CD++KA++P   D++LF   RL+  
Sbjct  220  PLDEKTGVEKTGFSNNWWVGLSMLHNLFTREHNVICDVMKAKYPDMTDQELFDKARLVNA  279

Query  337  GETIKIVIEEY---------------------VQQLSGY--FLQLKFDPE--LLFGVQFQ  371
                K+   E+                     + QL G+  FL+  F PE  +L G+   
Sbjct  280  AVMSKLHTVEWTPALLYNDILDVGMNSNWFGLLSQLGGFGNFLKRIF-PEHYILTGIPGS  338

Query  372  YRN------RIAMEFNHLYHWHPLMPD--------SFKVGSQEYSYEQFLFNTSMLV--D  415
             +        +  EF  +Y  H ++PD        S K   + Y  +  LF+ +  V   
Sbjct  339  AKELHGVPYSLTEEFTAVYRMHSILPDIIHLQDIKSAKRTGETYRLKDTLFSDAFKVVEK  398

Query  416  YGVEALVDAFSRQIAGRI------GGGRNMD-------HHILHVAVDVIRESREMRLQPF  462
             G+E L   F  +  G +         R++         ++    VDV+R+ RE  +  +
Sbjct  399  QGMENLFYTFGVENPGALVLHNYPNTIRDLQLPETQNAEYVDMATVDVLRD-RERGVPRY  457

Query  463  NEYRKRFGMKPYTSFQELVGEKEMAAELEELY-GDIDALEFYPGLLLEKCHPNSI-FGES  520
            NE R+   M P  +F+++  + ++A ELEE+Y GD++ ++   G + E   P    F ++
Sbjct  458  NELRRHLNMAPAETFRDITDDPKVAEELEEMYEGDVEMVDLLVGCMAESPRPTGFAFSDT  517

Query  521  MIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVC  568
               +    + + L  +   + +Y+   T+  E G + ++ AT+  ++ 
Sbjct  518  AFRLFILMATRRLQADRFYT-DYYNSDTYTQE-GLDWIENATMSSILL  563


>ref|XP_002211792.1|  hypothetical protein BRAFLDRAFT_120629 [Branchiostoma floridae]
 gb|EEA68702.1|  hypothetical protein BRAFLDRAFT_120629 [Branchiostoma floridae]
Length=601

 GENE ID: 7230817 BRAFLDRAFT_120629 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 91.7 bits (226),  Expect = 9e-18, Method: Compositional matrix adjust.
 Identities = 99/408 (24%), Positives = 171/408 (41%), Gaps = 81/408 (19%)

Query  219  FTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGI  278
            F  A  H  D   +YG + E Q  LR  KDGKLK  V    M                 I
Sbjct  179  FRNANTHWWDASQLYGSDAETQLALREMKDGKLK--VTSSGM-----------------I  219

Query  279  PPQSQMAVGQEVF--GLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI  336
            P   +  V +  F      GL +   L+ REHN +CD++KA++P   D++LF   RL+  
Sbjct  220  PLDEKTGVEKTGFSNNWWVGLSMLHNLFTREHNVICDVMKAKYPDMTDQELFDKARLVNA  279

Query  337  GETIKIVIEEY---------------------VQQLSGY--FLQLKFDPE--LLFGVQFQ  371
                K+   E+                     + QL G+  FL+  F PE  +L G+   
Sbjct  280  AVMSKLHTVEWTPALLYNDILDVGMNSNWFGLLSQLGGFGNFLKRIF-PEHYILTGIPGS  338

Query  372  YRN------RIAMEFNHLYHWHPLMPD--------SFKVGSQEYSYEQFLFNTSMLV--D  415
             +        +  EF  +Y  H ++PD        S K   + Y  +  LF+ +  V   
Sbjct  339  AKELHGVPYSLTEEFTAVYRMHSILPDIIHLQDIKSAKRTGETYRLKDTLFSDAFKVVEK  398

Query  416  YGVEALVDAFSRQIAGRI------GGGRNMD-------HHILHVAVDVIRESREMRLQPF  462
             G+E L   F  +  G +         R++         ++    VDV+R+ RE  +  +
Sbjct  399  QGMENLFYTFGVENPGALVLHNYPNTIRDLQLPETQNAEYVDMATVDVLRD-RERGVPRY  457

Query  463  NEYRKRFGMKPYTSFQELVGEKEMAAELEELY-GDIDALEFYPGLLLEKCHPNSI-FGES  520
            NE R+   M P  +F+++  + ++A ELEE+Y GD++ ++   G + E   P    F ++
Sbjct  458  NELRRHLNMAPAETFRDITDDPKVAEELEEMYEGDVEMVDLLVGCMAESPRPTGFAFSDT  517

Query  521  MIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVC  568
               +    + + L  +   + +Y+   T+  + G + ++ AT+  ++ 
Sbjct  518  AFRLFLLMATRRLQADRFYT-DYYNSDTY-TQKGLDWIENATMSSILL  563


>gb|ABK62699.1|  cyclooxygenase-1 [Oncorhynchus tshawytscha]
Length=61

 Score = 86.3 bits (212),  Expect = 4e-16, Method: Compositional matrix adjust.
 Identities = 40/62 (64%), Positives = 50/62 (80%), Gaps = 2/62 (3%)

Query  538  ICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPST  597
            ICSPEYWKPSTFGG+ GF+IV +A+L++LVCLNT  CPYV+F VP A Q++ P   + ST
Sbjct  2    ICSPEYWKPSTFGGQTGFDIVNSASLERLVCLNTNWCPYVAFNVPPAGQEEPP--RKQST  59

Query  598  EL  599
            EL
Sbjct  60   EL  61


>ref|XP_002227868.1|  hypothetical protein BRAFLDRAFT_125849 [Branchiostoma floridae]
 gb|EEA52661.1|  hypothetical protein BRAFLDRAFT_125849 [Branchiostoma floridae]
Length=1378

 GENE ID: 7210337 BRAFLDRAFT_125849 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 69.3 bits (168),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 81/335 (24%), Positives = 130/335 (38%), Gaps = 53/335 (15%)

Query  295   PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY  354
             PGL    T++LREHNR+   L   +P W D+++F  TR I+     KIV  E +  + G 
Sbjct  1038  PGLTSMHTVFLREHNRIARQLSTLNPLWNDDRVFLETRKIIGALMQKIVYGEDLPNVLGP  1097

Query  355   FLQLKFDPELL-----FGVQFQYRNRIAMEFNHLYH--WHPLMPDSFKVGSQEYS-----  402
                 KFD  L       G        I+  F+   +   H L+ + F   + +Y+     
Sbjct  1098  DAMAKFDLSLTDNGFYHGYDENANPTISNAFSTAAYRFGHSLVDEKFTRATPDYAPGAKC  1157

Query  403   ---YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRN------MDHHI---------L  444
                     FN S + D   +   D+  R +  +  G  N      +  H+         L
Sbjct  1158  PIQLAMSFFNPSHIFDND-QGGPDSIIRGLVSKASGLFNRFMVSDLTKHLFADPPGSVGL  1216

Query  445   HVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKE---MAAELEELYGDIDALE  501
              +A   I+  R+  L  +N +R+R G+     F +L  E         L  +Y D+D ++
Sbjct  1217  DLAALNIQRGRDHGLPGYNAWRERCGLPRARGFDDLEAEIPDWVTRHRLSSVYTDVDDID  1276

Query  502   FYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPI-CSPEYWKPSTFGGEVGFNI---  557
              + G L EK  P  + G +         L GL    +     +W    F     F     
Sbjct  1277  LFAGGLAEKSVPGGVVGPTFA------CLIGLQFQELRVGDRFW----FENSGQFTTDQL  1326

Query  558   --VKTATLKKLVCLNTKTCPYVS---FRVPDASQD  587
               +K   L +++C NT    ++    FR+P A  D
Sbjct  1327  AEIKNTMLARILCDNTDGTTHMQPDVFRLPRAGND  1361


 Score = 65.1 bits (157),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 64/257 (24%), Positives = 104/257 (40%), Gaps = 34/257 (13%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY  354
            PGL    T++LREHNR+   L   +P W D+++F  TR I+     KIV  E +  + G 
Sbjct  643  PGLTSMHTVFLREHNRIARQLSTLNPLWNDDRVFLETRKIIGALMQKIVYGEDLPNVLGP  702

Query  355  FLQLKFDPELL-----FGVQFQYRNRIAMEFNHLYH--WHPLMPDSFKVGSQEYS-----  402
                KF+  L       G        I+  F+   +   H L+ + F   + +Y+     
Sbjct  703  DAMAKFNLSLTENGFYHGYDENANPTISNAFSTAAYRFGHSLVDEKFTRATPDYAPGAKC  762

Query  403  ---YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRN------MDHHI---------L  444
                    FN S + D   +   D+  R +  +  G  N      +  H+         L
Sbjct  763  PIQLAMSFFNPSHIFDND-QGGPDSIIRGLVSKASGLFNRFMVSDLTKHLFADPPGSVGL  821

Query  445  HVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKE---MAAELEELYGDIDALE  501
             +A   I+  R+  L  +N +R+R G+     F +L  E         L  +Y D+D ++
Sbjct  822  DLAALNIQRGRDHGLPGYNAWRERCGLPRARGFDDLEAEIPDWVTRHRLSSVYTDVDDID  881

Query  502  FYPGLLLEKCHPNSIFG  518
             + G L EK  P  + G
Sbjct  882  LFAGGLAEKSVPGGVVG  898


>ref|XP_002126285.1|  PREDICTED: similar to oxidase/peroxidase [Ciona intestinalis]
Length=960

 GENE ID: 100177188 LOC100177188 | similar to oxidase/peroxidase
[Ciona intestinalis] (10 or fewer PubMed links)

 Score = 68.2 bits (165),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 88/394 (22%), Positives = 156/394 (39%), Gaps = 57/394 (14%)

Query  227  VDLGHIYGDNLERQYQLRLFKD---GKLKYQVL--------DGEMYPPSVEEAPVL----  271
            +D G++YG N +R++   + ++   G+LK  VL        +    P + +  P L    
Sbjct  239  LDAGNVYG-NSQREFNDLINQNSPAGELKIGVLGPHGSAPANAPTLPLTTQTGPQLGNKM  297

Query  272  -----MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQ  326
                 +H PR  P     A G +       L  + TL++R HN+V   LKA +P+W   +
Sbjct  298  VCPRGLHKPRHAP---CFAAGDQRANENSALTSFHTLFMRLHNKVVRDLKAINPSWSKLK  354

Query  327  LFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELL-----FGVQFQYRNRIAMEF-  380
            L QT R I+     +I  ++Y+  + G     +F   LL      G    Y   +   F 
Sbjct  355  LIQTGRSIVAAMHQRITYKQYLPAILGSQYMNRFGLTLLEQGYSNGYDASYDAGVINSFA  414

Query  381  -NHLYHWHPLMPDSFKVGSQEYSYE-------QFLFNTSMLVDY---GVEALVDAFSRQI  429
                   H  +P      +Q ++ +          FN++ L+     G  +++   S + 
Sbjct  415  AAAFRFGHSQIPGRLVRRNQHWAVQGTPILLRNSFFNSNPLLTTNFGGANSILRGLSNEP  474

Query  430  AGRIG------------GGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSF  477
            A +I               R    H L +A+++ R  R+  +  +N YR+ FG+K   SF
Sbjct  475  AQKIDPTLVDDLQDFLFAPRGRRGHDL-LAINIAR-GRDHGIPSYNAYRELFGLKKANSF  532

Query  478  QELVG-EKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGN  536
             + V         L+ LY +++ ++ Y G L E+       G     I A +  + L   
Sbjct  533  NDFVEIPPARRRSLQRLYRNVNDVDLYIGGLSERPVAGGSVGPVFASIIA-YQFRALKKG  591

Query  537  PICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLN  570
                 E     T         +++ TL +++C N
Sbjct  592  DRFWHENGAECTVFTPAQLAAIRSFTLSRIMCDN  625


>ref|XP_002250352.1|  hypothetical protein BRAFLDRAFT_133335 [Branchiostoma floridae]
 gb|EEA30150.1|  hypothetical protein BRAFLDRAFT_133335 [Branchiostoma floridae]
Length=1232

 GENE ID: 7238746 BRAFLDRAFT_133335 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 67.8 bits (164),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 79/334 (23%), Positives = 132/334 (39%), Gaps = 51/334 (15%)

Query  295   PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY  354
             PGL    T++LREHNR+   L   +P W ++++F  TR I+     KIV  E +  + G 
Sbjct  892   PGLTSMHTVFLREHNRIARQLSTLNPLWNEDRVFLETRKIIGALMQKIVYGEDLPNVLGP  951

Query  355   FLQLKFDPELL-----FGVQFQYRNRIAMEFNHLYH--WHPLMPDSFKVGSQEYS-----  402
                 KF+  L       G        I+  F+   +   H L+ + F   + +Y+     
Sbjct  952   DAMAKFNLSLTENGFYHGYDENANPTISNAFSTAAYRFGHSLVDEKFTRATPDYAPGAKC  1011

Query  403   ---YEQFLFNTSMLVDY---GVEALVDAFSRQIAGRIGG--GRNMDHHI---------LH  445
                     FN S + D    G ++++     Q +G        ++  H+         L 
Sbjct  1012  PIQLAMSFFNPSHIFDNDQGGPDSIIRGLVSQASGLFDRFMVSDLTKHLFADPPGSVGLD  1071

Query  446   VAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKE---MAAELEELYGDIDALEF  502
             +A   I+  R+  L  +N +R+R G+     F +L  E         L  +Y D+D ++ 
Sbjct  1072  LAALNIQRGRDHGLPGYNAWRERCGLSRAHGFDDLEAEIPDWVTRHRLSSVYTDVDDIDL  1131

Query  503   YPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPI-CSPEYWKPSTFGGEVGFNI----  557
             + G L EK  P  + G +         L GL    +     +W    F     F      
Sbjct  1132  FAGGLAEKSVPGGVVGPTFA------CLIGLQFQELRVGDRFW----FENSGQFTTDQLA  1181

Query  558   -VKTATLKKLVCLNTKTCPYVS---FRVPDASQD  587
              +K  TL +++C NT    ++    FR+P A  D
Sbjct  1182  EIKNTTLARILCDNTDGTTHMQPDVFRLPRAGND  1215


>emb|CAL30145.1|  cyclooxygenase-2 [Sparus aurata]
Length=64

 Score = 67.8 bits (164),  Expect = 1e-10, Method: Composition-based stats.
 Identities = 32/57 (56%), Positives = 40/57 (70%), Gaps = 2/57 (3%)

Query  542  EYWKPSTFGGEVGFNIVKTATLKKLVCLNTK-TCPYVSFRVPDASQDDGPAVERPST  597
            EYWKPSTFGG VGF+I+ TA+L++LVC N K  CP  SF VPD  ++ G  +   ST
Sbjct  1    EYWKPSTFGGTVGFDIINTASLQRLVCNNVKGPCPVASFHVPDV-KETGSVIINSST  56


>dbj|BAA83376.1|  BbTPO [Branchiostoma belcheri]
Length=764

 Score = 67.0 bits (162),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 75/321 (23%), Positives = 126/321 (39%), Gaps = 45/321 (14%)

Query  227  VDLGHIYGDNLERQYQLRLFK--DGKLKYQ----VLDGEMYPPSVEEAPVLMHYPRGIPP  280
            +D   +YG   E    LR F   DG L+ Q    +  G    P  +     +  P G   
Sbjct  355  IDASQVYGSTSELAQSLRDFSTDDGLLRVQEGADISSGMDLLPFQDGETSCLQDPNGGDI  414

Query  281  QSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETI  340
                  G      +  L+   T+WLREHNR+   LK  +P W  EQ++Q  R I+  E  
Sbjct  415  VPCFLAGDGRSNEVNTLIASHTIWLREHNRIARELKRINPHWKGEQIYQEARKIVGSEMQ  474

Query  341  KIVIEEYVQQLSG--YFLQL----KFDPELLFGVQFQYRNRIAM---------------E  379
             I   EY+ ++ G     Q+     +DP     V    RN  A                 
Sbjct  475  HITYTEYLPKILGPRGMDQIGEYTGYDP----NVNPSTRNEFATAAFRFGHAAIGGTVRR  530

Query  380  FNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNM  439
            F+  Y   P + +   V   E  +  +       +D  V  L+  F++ +         +
Sbjct  531  FDENYEEDPQIGN---VALHETFFSPWRIVRESGIDSVVRGLMGGFAKLVTPTDVMHEEL  587

Query  440  DHHIL----HVAVDV----IRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAA  488
              ++      +A+D+     +  R+  L  +N++R    +    SF +L GE    ++  
Sbjct  588  SQNLFALMNQIALDLASLNTQRGRDHALPFYNDWRVFCNLPRAESFDDLSGEISNSDVRD  647

Query  489  ELEELYGDIDALEFYPGLLLE  509
             L ++YGD++ ++ +PG LLE
Sbjct  648  TLADVYGDVNNIDLWPGALLE  668


>ref|XP_002121550.1|  PREDICTED: similar to peroxidasin homolog [Ciona intestinalis]
Length=1642

 GENE ID: 100185463 LOC100185463 | similar to peroxidasin homolog
[Ciona intestinalis]

 Score = 66.2 bits (160),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 73/319 (22%), Positives = 130/319 (40%), Gaps = 48/319 (15%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
              L    TLW+REHNR+   +K  +  W  + +F  TR I+  +   I    ++ +L G F
Sbjct  1198  SLTTMHTLWMREHNRIARYIKQVNQHWDGDTIFHETRKIIGAQMQHITYTHWLPKLLGPF  1257

Query  356   LQL-----KFDPELLFGVQFQYRNRIAMEFNH------LYH----WHPLMPDSFKVGSQE  400
               L      +DP L   +   +    A  F H      +Y     WH     +  +    
Sbjct  1258  TSLIGEYRGYDPNLPSSIVNVFAT-AAYRFGHTMINPIMYRLNETWHESRYGNLNL----  1312

Query  401   YSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL--------HVAVDV--  450
               +E F     ++ + G++ L+     +         NM+  ++         VA+D+  
Sbjct  1313  --HEAFFAPFRIVHEGGIDPLIRGLIAKPMKARDSDSNMNEELIERLFSMAEEVALDLGA  1370

Query  451   --IRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPG  505
               I+  R+  L  +NE+R+   +   T+F +L  E    E+  +L ELY     ++ + G
Sbjct  1371  LNIQRGRDHALPFYNEWRQFCNLSSATTFDDLATEIKNPEVRNKLRELYKVPANIDPFVG  1430

Query  506   LLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFNIVKTATL  563
             +++E   P S  G ++  +      +   G+      +W   P  F      N +K A+L
Sbjct  1431  MIVEDVVPGSRLGPTLACLLTEQFKRTRAGD-----RFWYENPGIF-SPTQVNALKQASL  1484

Query  564   KKLVCLNT---KTCPYVSF  579
              +++C NT   KT P   F
Sbjct  1485  ARVICDNTDSIKTVPRDVF  1503


>ref|XP_002224222.1|  hypothetical protein BRAFLDRAFT_86521 [Branchiostoma floridae]
 gb|EEA56349.1|  hypothetical protein BRAFLDRAFT_86521 [Branchiostoma floridae]
Length=770

 GENE ID: 7242190 BRAFLDRAFT_86521 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 63.2 bits (152),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 73/320 (22%), Positives = 129/320 (40%), Gaps = 45/320 (14%)

Query  227  VDLGHIYGDNLERQYQLRLF--KDGKLKYQ----VLDG-EMYPPSVEEAPVLMHYPRGIP  279
            +D   +YG + E    LR     +G L+ Q    +  G ++ P   EE       P G  
Sbjct  243  IDASMVYGSSEELAQSLRDLTTDEGLLRVQERTDISSGLDLLPFEEEEENSCNQDPTGGD  302

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
                   G          +   T+W+REHNR+   L+  +P W  ++L+Q  R I+    
Sbjct  303  TVPCFLSGDSRVNEDNTAIASHTIWVREHNRLARQLRTLNPHWSGDRLYQEARNIVAAVI  362

Query  340  IKIVIEEYVQQLSGYFLQ------LKFDPELLFGVQFQYRNRIAMEFNHLYHW--HPLMP  391
              I  EEY+ ++ G          +++DPE    V    RN  AM    L      PL+ 
Sbjct  363  AHITFEEYLPKILGPDAMEEVGEYVEYDPE----VDPSLRNSFAMAAFRLNDAATAPLV-  417

Query  392  DSFKVGSQEYSYEQFLFNTSMLVDYGV------EALVDAFSRQIAG---RIGGGRNM---  439
               K   + Y  ++ + N ++   +        E+ +D   R + G   ++   RN+   
Sbjct  418  ---KRYDENYEEDRDIGNIALRHTFFAPWRIVKESGIDPLVRGLIGSPAKLATPRNVIHK  474

Query  440  ----------DHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAE  489
                      DH  L +A   I+  R+  +  +N +R    +    SF +L  + ++  +
Sbjct  475  ELTQHLFGQPDHPGLDIAAITIQRGRDHGIPFYNNWRDLCELPLAESFGDLSSDADVRQK  534

Query  490  LEELYGDIDALEFYPGLLLE  509
            L ++YGD+  ++ +   LLE
Sbjct  535  LSDVYGDVSNIDLWTAGLLE  554


>ref|XP_002205093.1|  hypothetical protein BRAFLDRAFT_67515 [Branchiostoma floridae]
 gb|EEA75400.1|  hypothetical protein BRAFLDRAFT_67515 [Branchiostoma floridae]
Length=842

 GENE ID: 7220088 BRAFLDRAFT_67515 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 62.8 bits (151),  Expect = 5e-09, Method: Compositional matrix adjust.
 Identities = 75/320 (23%), Positives = 122/320 (38%), Gaps = 42/320 (13%)

Query  227  VDLGHIYGDNLERQYQLRLFK--DGKLKYQ----VLDGEMYPPSVEEAPVLMHYPRGIPP  280
            +D  ++YG        LR F   DG L+ Q    +  G   P   E        P G   
Sbjct  239  IDASNVYGSKFAFAQSLRDFSTDDGLLRVQEGEDISSGMASPFQNEAVTSCNQDPNGGDI  298

Query  281  QSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETI  340
                  G      +  L+   T+W+REHNR+   LK  +P W  EQ++Q  R I+  E  
Sbjct  299  VPCFLAGDGRVNEVNTLIASHTIWVREHNRLARELKRINPHWDGEQIYQEARKIVGSEMQ  358

Query  341  KIVIEEYVQQLSGYFLQLKFDPELLFG-----VQFQYRNRIAMEFNHLYHWH-PLMPDSF  394
             I   EY+ ++ G   Q   D    +      V    RN  A       H         F
Sbjct  359  HITFTEYLPKILG---QRGMDQMGEYAGYNPNVNPSTRNEFATAAFRFGHAAIGAFVRRF  415

Query  395  KVGSQEYSYEQFLFNTSMLVDYGV--EALVDAFSRQIAGRIGGGRNM--DHHILH-----  445
                QE +      + +    + V  E+ +D   R   G IGG   +     +LH     
Sbjct  416  DENYQEAAIGNVALSDAFFSPWRVFRESGIDPVVR---GLIGGFAKLVTPTDVLHEELSQ  472

Query  446  --------VAVDV----IRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAEL  490
                    +A+D+     +  R+  +  +N++R    +    SF +L GE   +++   L
Sbjct  473  NLFKLRNQIALDLASLNTQRGRDHGIPFYNDWRVFCNLTRAASFDDLSGEISNQDVRDTL  532

Query  491  EELYGDIDALEFYPGLLLEK  510
             ++YGD++ ++ +P   LE 
Sbjct  533  ADVYGDVNNIDLWPAAQLED  552


>ref|XP_002221817.1|  hypothetical protein BRAFLDRAFT_123696 [Branchiostoma floridae]
 gb|EEA58724.1|  hypothetical protein BRAFLDRAFT_123696 [Branchiostoma floridae]
Length=738

 GENE ID: 7233930 BRAFLDRAFT_123696 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 61.6 bits (148),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 69/318 (21%), Positives = 125/318 (39%), Gaps = 38/318 (11%)

Query  227  VDLGHIYGDNLERQYQLRLFK--DGKLKYQ----VLDG-EMYPPSVEEAPVLMHYPRGIP  279
            +D  ++YG  L+    LR     DG L+ Q    +  G ++ P   E        P+G  
Sbjct  327  IDASNVYGSTLDVAQSLRDLSNDDGLLRVQEGADISSGMDLLPFQDEVVSSCNQDPKGGD  386

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
                   G      +  L+   T+WLREHNR+   LK+ +P W  E ++Q  R I+  E 
Sbjct  387  TIPCFLAGDVRSNEVNTLIASHTIWLREHNRIAKELKSINPRWDGETIYQEARKIVGAEM  446

Query  340  IKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQ  399
              I   EY+ ++ G     +      +        R           H  +  + +   +
Sbjct  447  QHITYTEYLPKILGPAGMDQIGEYSKYNASVNPSTRNEFATAAFRFGHAAISGTVRRFDE  506

Query  400  EYSYEQFLFNTSMLVDYGV------EALVDAFSRQIAGRIGGG------RNMDHHIL---  444
             Y  +  + N ++   +        E+ VD   R   G IGG        N+ H  L   
Sbjct  507  NYVEDPVIGNVALRDTFFSPWRIFNESGVDPVVR---GLIGGSAKLVTPTNVMHEELSQG  563

Query  445  ------HVAVDV----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELE  491
                   +A+D+     +  R+  L  +N++R   G+    +F +L   + +  +  +L 
Sbjct  564  LFALKNQIALDLAALNTQRGRDHGLPFYNDWRVFCGLSRAETFSDLEDEIKDSTVRDKLA  623

Query  492  ELYGDIDALEFYPGLLLE  509
            ++YGD++ ++ +P   LE
Sbjct  624  DVYGDVNNIDLWPAAQLE  641


>gb|AAK52826.1|AF364820_1  peroxidase 2 [Xenopus laevis]
Length=410

 GENE ID: 373710 pox2-A | peroxidase 2 [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 60.5 bits (145),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 89/388 (22%), Positives = 153/388 (39%), Gaps = 70/388 (18%)

Query  228  DLGHIYGDNLERQYQLRL----FKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQ  283
            DL  +  +N  RQ  L      F DG L Y       +    E+  +L +   G+P    
Sbjct  4    DLARMLRNNTARQLGLMAVNTRFTDGGLPYLP-----FSTMKEDFCLLTNESSGLP---C  55

Query  284  MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIV  343
               G       PGL  + T+++REHNR+ + L+  +P W  E LFQ TR I+     KI 
Sbjct  56   FLAGDSRVSEQPGLTAFHTIFVREHNRIANNLRRMNPNWTGEVLFQETRKIIGAIEQKIN  115

Query  344  IEEYVQQLSG------------YFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP  391
             ++Y+  L G            Y   +      +F + F+  + +   F  +Y     + 
Sbjct  116  YKDYLPLLLGSTMPRVLPRYTSYSDSVNPGASNVFSLIFRMGHTMIQPF--IYR----LV  169

Query  392  DSFKVGSQ--EYSYEQFLFNTSMLV-DYGVEALVDAFSRQIAGRIGGGRN-------MDH  441
            D ++  +        +  FNT  +V + GV+ L+      IA +    R        +  
Sbjct  170  DGYRTSASLPPVPLHRTFFNTWRVVREGGVDPLLRGL---IANQAKLNRQDQILVDELRE  226

Query  442  HI--------LHVAVDVIRESREMRLQPFNEYRKRFGM---KPYTSFQELVGEKEMAAEL  490
            H+        L +    ++  R+  L  +N YR+  G+   +  +    ++  K++A +L
Sbjct  227  HLFELFKRLGLDLGAINMQRGRDHGLPGYNAYRRLCGLSQPRNESDLATVLRNKQLAQKL  286

Query  491  EELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPE------YW  544
              LYG  + ++ + G + E    N   GE          L  L+GN            Y 
Sbjct  287  ISLYGTPENIDIWLGAVAEPLITNGRVGE---------LLACLIGNQFRRTRDGDRFYYE  337

Query  545  KPSTFGGEVGFNIVKTATLKKLVCLNTK  572
            +P  F        ++ ATL ++VC NT+
Sbjct  338  RPGVF-TPAQLRSIEKATLARIVCDNTR  364


>emb|CAG05549.1|  unnamed protein product [Tetraodon nigroviridis]
Length=1632

 Score = 60.5 bits (145),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 83/369 (22%), Positives = 138/369 (37%), Gaps = 82/369 (22%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKY-------QVLDGEMYPPSVEEAPVLMHYPRGIP  279
            +D   IYG +      LR F  G L         +  +G  +  S  +     H P+G+ 
Sbjct  176  IDGSSIYGPSASWSDSLRSFSGGLLASGSEWNMPRQAEGRTFMWSAADPCTGEHGPQGLY  235

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
                    + +F    G+     +W R HN +   L+ EHP W DE+LFQ  R I++   
Sbjct  236  ELGNSWANENIFTAAEGI-----IWFRYHNYLASRLQQEHPAWSDEELFQNARKIVVATF  290

Query  340  IKIVIEEYV------QQLSGY-----FLQLKFDPELL-----FGVQF----QYRNRIAME  379
              I + E++      ++L  Y     F+     PEL+     FG+       Y       
Sbjct  291  QNIALYEWLPAHLGDRELPPYPGYQKFVDPGISPELVAAAMRFGITMVPPGVYMRNKTCH  350

Query  380  FNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGR-----IG  434
            F  + +       + ++ +  +S       TS  +D+    L+   + QIA R     + 
Sbjct  351  FQEVVNLDGSSSPALRLCNSFWSRRSPNMKTSQDLDH----LLFGMASQIAEREDNIVVE  406

Query  435  GGRNMDHHILH------VAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGE-----  483
              R+  +  L       VAV  I+  R+  L+ + E R    + P  SF +L  E     
Sbjct  407  DLRDFMYGPLRFTRTDLVAV-TIQRGRDFGLRSYTEVRNSLDLPPVGSFDDLNPELSSSD  465

Query  484  ---------------------------KEMAAELEELY-GDIDALEFYPGLLLEKC-HPN  514
                                       +++  ++ ELY GDI  LE +PG LLE    P 
Sbjct  466  PKVKPTNQSSWEGQRLTNVLGVSLSRPRQLLRDIAELYNGDISKLELFPGGLLESSGSPG  525

Query  515  SIFGESMIE  523
             +F   +++
Sbjct  526  PVFSAIILD  534


>tpd|FAA00349.1|  TPA: predicted dual oxidase [Tetraodon nigroviridis]
Length=1619

 Score = 60.5 bits (145),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 83/369 (22%), Positives = 138/369 (37%), Gaps = 82/369 (22%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKY-------QVLDGEMYPPSVEEAPVLMHYPRGIP  279
            +D   IYG +      LR F  G L         +  +G  +  S  +     H P+G+ 
Sbjct  176  IDGSSIYGPSASWSDSLRSFSGGLLASGSEWNMPRQAEGRTFMWSAADPCTGEHGPQGLY  235

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
                    + +F    G+     +W R HN +   L+ EHP W DE+LFQ  R I++   
Sbjct  236  ELGNSWANENIFTAAEGI-----IWFRYHNYLASRLQQEHPAWSDEELFQNARKIVVATF  290

Query  340  IKIVIEEYV------QQLSGY-----FLQLKFDPELL-----FGVQF----QYRNRIAME  379
              I + E++      ++L  Y     F+     PEL+     FG+       Y       
Sbjct  291  QNIALYEWLPAHLGDRELPPYPGYQKFVDPGISPELVAAAMRFGITMVPPGVYMRNKTCH  350

Query  380  FNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGR-----IG  434
            F  + +       + ++ +  +S       TS  +D+    L+   + QIA R     + 
Sbjct  351  FQEVVNLDGSSSPALRLCNSFWSRRSPNMKTSQDLDH----LLFGMASQIAEREDNIVVE  406

Query  435  GGRNMDHHILH------VAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGE-----  483
              R+  +  L       VAV  I+  R+  L+ + E R    + P  SF +L  E     
Sbjct  407  DLRDFMYGPLRFTRTDLVAV-TIQRGRDFGLRSYTEVRNSLDLPPVGSFDDLNPELSSSD  465

Query  484  ---------------------------KEMAAELEELY-GDIDALEFYPGLLLEKC-HPN  514
                                       +++  ++ ELY GDI  LE +PG LLE    P 
Sbjct  466  PKVKPTNQSSWEGQRLTNVLGVSLSRPRQLLRDIAELYNGDISKLELFPGGLLESSGSPG  525

Query  515  SIFGESMIE  523
             +F   +++
Sbjct  526  PVFSAIILD  534


>tpd|FAA00329.1|  TPA: predicted dual oxidase-B [Ciona intestinalis]
Length=1496

 GENE ID: 100170038 duox-b | dual oxidase-B [Ciona intestinalis]
(10 or fewer PubMed links)

 Score = 60.5 bits (145),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 80/346 (23%), Positives = 142/346 (41%), Gaps = 64/346 (18%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGE------------MYPPSVEEAPVLMHY  274
            +D   IYG++      LR F+ G+LK +  DG             +Y P+++    L   
Sbjct  138  LDGSVIYGNSHSWSEHLRSFERGRLKEE--DGHPGYPSFNRNEIPLYNPTID----LKRP  191

Query  275  PRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLI  334
            P+   P+  ++ G       P LM    +W R HN + + +  ++P W D+Q+F   R  
Sbjct  192  PKTRNPEELLSFGNPRGNENPFLMTIEIIWFRWHNHLAEKIAVQNPDWSDQQIFDKARKW  251

Query  335  LIGETIKIVIEEYVQQLSG-----YFLQLKFDPELLFGVQFQYRNRIAMEFNHLY-----  384
             I     I   E++ ++ G     Y    KF   +L  V  ++ +  AM   H       
Sbjct  252  TIATYQNIAFYEWLPEIIGTSPPPYREYNKF---MLPSVSVEF-SIAAMRLGHSLVPSGV  307

Query  385  -----HWHPL--MPDSFKVGSQEYSYEQFLFNT-----SMLVDYGVEALVDAFSRQ----  428
                    P+  +P+ +   + E +    L NT       L+D G+E +V   + Q    
Sbjct  308  VLRQPDCSPIDPLPEDYLASAGEPALR--LCNTYWQLQDALLDLGIEGIVLGMTSQNAEE  365

Query  429  --------IAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL  480
                    +AG + G   +    + +    I+  R+  LQ +NE RK + + P T F +L
Sbjct  366  EDAVVVDDLAGFLYGP--LKRTRMDLEAMTIQRGRDAGLQRYNEVRKTYDLPPITDFSQL  423

Query  481  VGE--KEMAAELEELY-GDIDALEFY-PGLLLEKCHPNSIFGESMI  522
                  E+ A L   Y  D + LE Y  G++ ++ + +++    +I
Sbjct  424  NPSLPNEVIARLRNAYNNDTNKLELYVAGMMEDRSNASNVLFYKII  469


>ref|XP_002123782.1|  PREDICTED: dual oxidase-B [Ciona intestinalis]
Length=1540

 GENE ID: 100170038 duox-b | dual oxidase-B [Ciona intestinalis]
(10 or fewer PubMed links)

 Score = 60.5 bits (145),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 80/346 (23%), Positives = 142/346 (41%), Gaps = 64/346 (18%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGE------------MYPPSVEEAPVLMHY  274
            +D   IYG++      LR F+ G+LK +  DG             +Y P+++    L   
Sbjct  182  LDGSVIYGNSHSWSEHLRSFERGRLKEE--DGHPGYPSFNRNEIPLYNPTID----LKRP  235

Query  275  PRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLI  334
            P+   P+  ++ G       P LM    +W R HN + + +  ++P W D+Q+F   R  
Sbjct  236  PKTRNPEELLSFGNPRGNENPFLMTIEIIWFRWHNHLAEKIAVQNPDWSDQQIFDKARKW  295

Query  335  LIGETIKIVIEEYVQQLSG-----YFLQLKFDPELLFGVQFQYRNRIAMEFNHLY-----  384
             I     I   E++ ++ G     Y    KF   +L  V  ++ +  AM   H       
Sbjct  296  TIATYQNIAFYEWLPEIIGTSPPPYREYNKF---MLPSVSVEF-SIAAMRLGHSLVPSGV  351

Query  385  -----HWHPL--MPDSFKVGSQEYSYEQFLFNT-----SMLVDYGVEALVDAFSRQ----  428
                    P+  +P+ +   + E +    L NT       L+D G+E +V   + Q    
Sbjct  352  VLRQPDCSPIDPLPEDYLASAGEPALR--LCNTYWQLQDALLDLGIEGIVLGMTSQNAEE  409

Query  429  --------IAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL  480
                    +AG + G   +    + +    I+  R+  LQ +NE RK + + P T F +L
Sbjct  410  EDAVVVDDLAGFLYGP--LKRTRMDLEAMTIQRGRDAGLQRYNEVRKTYDLPPITDFSQL  467

Query  481  VGE--KEMAAELEELY-GDIDALEFY-PGLLLEKCHPNSIFGESMI  522
                  E+ A L   Y  D + LE Y  G++ ++ + +++    +I
Sbjct  468  NPSLPNEVIARLRNAYNNDTNKLELYVAGMMEDRSNASNVLFYKII  513


>gb|AAK91661.1|AF378824_1  myeloid-specific peroxidase [Danio rerio]
Length=678

 GENE ID: 337514 mpx | myeloid-specific peroxidase [Danio rerio]
(Over 10 PubMed links)

 Score = 60.1 bits (144),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 66/256 (25%), Positives = 107/256 (41%), Gaps = 38/256 (14%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG-  353
            P L    TL++REHNR+   L   +PTW  E L+Q  R I+      +VI+EY+  + G 
Sbjct  310  PALNSLHTLFVREHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLPLIVGP  369

Query  354  --YFLQLKFDPELLFGVQFQYRN---RIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQF--  406
              Y   L   P     V     N     A  F HL     + P  F++     ++ QF  
Sbjct  370  DAYNRHLGPYPGYNENVDPTIANVFATAAFRFAHLT----IQPFIFRLDENYKNHPQFPS  425

Query  407  -----LFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL------------HVAVD  449
                  F +   V +  E  +D   R + GR       DH ++            H+A+D
Sbjct  426  VPLYEAFFSPWRVIF--EGGIDPVLRGLIGRPAKLNTQDHMLVNALRERLFAFTSHIALD  483

Query  450  V----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEF  502
            +    ++  R+  +  +N +R+  G+    + QEL   +   E+A +L ELYG  + ++ 
Sbjct  484  LASLNMQRGRDHAIPGYNAWRRFCGLSAPQNEQELAVVMNNTELARKLIELYGTPENIDV  543

Query  503  YPGLLLEKCHPNSIFG  518
            + G + E   P    G
Sbjct  544  WLGGVAEPFAPGGRVG  559


>gb|AAH56287.1|  Mpx protein [Danio rerio]
Length=893

 GENE ID: 337514 mpx | myeloid-specific peroxidase [Danio rerio]
(Over 10 PubMed links)

 Score = 58.9 bits (141),  Expect = 7e-08, Method: Compositional matrix adjust.
 Identities = 66/256 (25%), Positives = 107/256 (41%), Gaps = 38/256 (14%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG-  353
            P L    TL++REHNR+   L   +PTW  E L+Q  R I+      +VI+EY+  + G 
Sbjct  394  PALNSLHTLFVREHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLPLIVGT  453

Query  354  --YFLQLKFDPELLFGVQFQYRN---RIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQF--  406
              Y   L   P     V     N     A  F HL     + P  F++     ++ QF  
Sbjct  454  DAYNRHLGPYPGYNENVDPTIANVFATAAFRFAHL----TIQPFIFRLDENYKNHPQFPS  509

Query  407  -----LFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL------------HVAVD  449
                  F +   V +  E  +D   R + GR       DH ++            H+A+D
Sbjct  510  VPLYEAFFSPWRVIF--EGGIDPVLRGLIGRPAKLNTQDHMLVNALRERLFAFTSHIALD  567

Query  450  V----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEF  502
            +    ++  R+  +  +N +R+  G+    + QEL   +   E+A +L ELYG  + ++ 
Sbjct  568  LASLNMQRGRDHAIPGYNAWRRFCGLSAPQNEQELAVVMNNTELARKLIELYGTPENIDI  627

Query  503  YPGLLLEKCHPNSIFG  518
            + G + E   P    G
Sbjct  628  WLGGVAEPFAPGGRVG  643


>ref|XP_002246054.1|  hypothetical protein BRAFLDRAFT_252340 [Branchiostoma floridae]
 gb|EEA34438.1|  hypothetical protein BRAFLDRAFT_252340 [Branchiostoma floridae]
Length=570

 GENE ID: 7229879 BRAFLDRAFT_252340 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 58.5 bits (140),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 104/431 (24%), Positives = 164/431 (38%), Gaps = 109/431 (25%)

Query  227  VDLGHIYGDNLERQYQLR--LFKDGKLKYQVLDG-----EMYPPSVEEAPVLMHYPRGIP  279
            +D   +YG + E    LR      G+LK +   G     E+ P ++ E     H P    
Sbjct  160  IDASMVYGSSDEELEHLRDPSLGRGQLKSKSNPGDSTKKELLPSAITEE---FHCPESSN  216

Query  280  PQSQ----MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLIL  335
            P S+       G       P L    T+WLREHNR+   L   +  W ++++F  TR I+
Sbjct  217  PSSRNQPCFQAGDVRVNEQPALTSMHTIWLREHNRIAARLADINSHWDEDRVFYETRKIV  276

Query  336  --------IGETIKIVI-----EEY--VQQLSGYF--LQLKFDPEL---------LFG--  367
                      E + IV+      EY  V + +GY+       DP +          FG  
Sbjct  277  GAMIQQITYAEDLPIVLGLNAMNEYGLVLRRNGYYNGYDETVDPTISNVFATAAYRFGHS  336

Query  368  -VQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALV----  422
             V+ Q+  R    +NH  H    +  SF          Q ++NT   V  G++++V    
Sbjct  337  LVKSQFE-RSTSSYNHNAHSPVQLTHSF-------FNPQHVYNT---VQGGLDSIVRGLA  385

Query  423  ----DAFSRQI------------AGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYR  466
                + F R I            AG +G         L +A   I+  R+  L  +N +R
Sbjct  386  STPHEKFDRFIVSGLTKNLFADPAGSLG---------LDLAALNIQRGRDHGLPGYNAWR  436

Query  467  KRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI-  522
               G+    SF +L  E       A+L +LY  +D ++ +   L E+  P  + G +   
Sbjct  437  VLCGLPRARSFDDLATEIPDASTRAKLADLYSHVDDIDLFAAGLAERSVPGGLLGPTFTC  496

Query  523  EIGAPFS--LKGLLGNPICSPEYWKPSTFGGEVGFNI-----VKTATLKKLVCLNTKTCP  575
             IG  F    KG          +W    F  +  F+      V+  TL +++C NT    
Sbjct  497  LIGRQFRELRKG--------DRFW----FENQGQFSQRQLGEVRKVTLARVLCDNTDDTS  544

Query  576  YVS---FRVPD  583
             +    F +PD
Sbjct  545  SMQRHVFELPD  555


>ref|NP_997944.1|  myeloid-specific peroxidase [Danio rerio]
 gb|AAK83239.1|  myeloperoxidase [Danio rerio]
Length=762

 GENE ID: 337514 mpx | myeloid-specific peroxidase [Danio rerio]
(Over 10 PubMed links)

 Score = 58.2 bits (139),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 65/256 (25%), Positives = 107/256 (41%), Gaps = 38/256 (14%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG-  353
            P L    TL++REHNR+   L   +PTW  E L+Q  R I+      +VI+EY+  + G 
Sbjct  394  PALNSLHTLFVREHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLPLIVGP  453

Query  354  --YFLQLKFDPELLFGVQFQYRN---RIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQF--  406
              Y   L   P     V     N     A  F HL     + P  F++     ++ QF  
Sbjct  454  DAYNRHLGPYPGYNENVDPTIANVFATAAFRFAHLT----IQPFIFRLDENYKNHPQFPS  509

Query  407  -----LFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL------------HVAVD  449
                  F +   V +  E  +D   R + GR       DH ++            H+A+D
Sbjct  510  VPLYEAFFSPWRVIF--EGGIDPVLRGLIGRPAKLNTQDHMLVNALRERLFAFTSHIALD  567

Query  450  V----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEF  502
            +    ++  R+  +  +N +R+  G+    + QEL   +   ++A +L ELYG  + ++ 
Sbjct  568  LASLNMQRGRDHAIPGYNAWRRFCGLSAPQNEQELAVVMNNTKLARKLIELYGTPENIDV  627

Query  503  YPGLLLEKCHPNSIFG  518
            + G + E   P    G
Sbjct  628  WLGGVAEPFAPGGRVG  643


>ref|XP_001921183.1|  PREDICTED: similar to peroxidasin, partial [Danio rerio]
Length=771

 GENE ID: 570177 LOC570177 | similar to peroxidasin [Danio rerio]

 Score = 58.2 bits (139),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 71/338 (21%), Positives = 140/338 (41%), Gaps = 45/338 (13%)

Query  296  GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
            GL    T+WLREHNR+   L   +P W  + ++   R I+  +   I   +++ ++ G  
Sbjct  281  GLTAMHTVWLREHNRIASELLRLNPHWDGDTIYHEARKIVGAQMQHITYNQWLPKILGEA  340

Query  356  LQ------LKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM---PDSFKVGSQEY-SYEQ  405
                      ++P +  G+   +    A  F H    +P++    ++F+   Q + S  +
Sbjct  341  GMRIMGDYTGYNPNINAGILNAFAT-AAFRFGHTL-INPILYRLDENFQPIQQGHISLHK  398

Query  406  FLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHVAVD  449
              F+   +V+   E  +D   R + G  G  R               +M H + L +A  
Sbjct  399  AFFSPFRIVN---EGGIDPLLRGLFGVAGKMRMSTQLLNTELTERLFSMAHAVALDLAAM  455

Query  450  VIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKE---MAAELEELYGDIDALEFYPGL  506
             I+  R+  +  +N+YR    +    +F++L  E +   +  +L+ LYG    ++ +P L
Sbjct  456  NIQRGRDHGIPSYNDYRVFCNLTSAQTFEDLKNEIQNPSVREKLQRLYGTPLNVDLFPAL  515

Query  507  LLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFNIVKTATLK  564
            + E+  P S  G +++ + A    +   G+      +W   P +F        +K  +L 
Sbjct  516  MAEELVPGSRLGPTLMCLLATQFKRLRDGD-----RFWYENPGSF-SPAQLTQLKQTSLS  569

Query  565  KLVCLNTKTCPYV---SFRVPDASQDDGPAVERPSTEL  599
            +++C N      +   +F V D     G   + P  +L
Sbjct  570  RVLCDNGDNITRIQSDAFSVADLPHGYGSCADLPKIDL  607


>emb|CAF99300.1|  unnamed protein product [Tetraodon nigroviridis]
Length=781

 Score = 57.8 bits (138),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 62/244 (25%), Positives = 106/244 (43%), Gaps = 34/244 (13%)

Query  296  GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
             L    TL++REHNR+   LK  +P W  E L+Q TR I+   T   V ++Y+  + G  
Sbjct  449  ALTSIHTLFVREHNRLARELKRLNPQWDSETLYQETRKIMGAYTQVFVFQDYLPHIVGTE  508

Query  356  LQLK-------FDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPD---SFKVGSQEYSYEQ  405
               +       ++P +   +   +    A  F HL    P++     +++  SQ  S   
Sbjct  509  AMRRQLGRYPGYNPNVDPSISNVFAT-AAYRFAHLA-IQPMLSRLDANYRENSQFPSVSL  566

Query  406  F-LFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL------------HVAVDV--  450
            F  F T   V +  E  +D   R + GR       DH ++            HVA+D+  
Sbjct  567  FKAFFTPWRVIF--EGGIDPLLRGLIGRPAKLNTQDHMLVNALREKLFQFVQHVALDLGS  624

Query  451  --IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPG  505
              ++  R+  L  +N +R+  G+    + QEL   +   ++A  L +LYG  D ++ + G
Sbjct  625  LNMQRGRDHALPGYNAWRRFCGLSQPRNQQELALVLNNTDLARRLLQLYGTPDNIDVWLG  684

Query  506  LLLE  509
             + E
Sbjct  685  GVAE  688


>ref|XP_002236954.1|  hypothetical protein BRAFLDRAFT_99381 [Branchiostoma floridae]
 gb|EEA43557.1|  hypothetical protein BRAFLDRAFT_99381 [Branchiostoma floridae]
Length=1501

 GENE ID: 7252732 BRAFLDRAFT_99381 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 57.4 bits (137),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 81/350 (23%), Positives = 130/350 (37%), Gaps = 47/350 (13%)

Query  259   EMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAE  318
             E+ P + EE   L     G   Q+  A G       PGL    T +LREHNR+   L   
Sbjct  1125  ELLPSNTEEMDFLCEESTG--NQTCSAAGDIRVNEQPGLTSMHTAFLREHNRIARGLSRI  1182

Query  319   HPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF-------------DPELL  365
             +P+W D+++F  TR I+     KI   E +  + G     +F             DP + 
Sbjct  1183  NPSWDDDRVFYETRKIVGALMQKITYGEDLPHVLGPAAMTRFHLTLTQSGFFSGYDPNVN  1242

Query  366   FGVQFQYRNRIAMEFNHLY---HWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDY---GVE  419
               +   +    A  F H      ++   PD  +  +         FN S + D    G +
Sbjct  1243  PTISNIFAT-AAYRFGHSLVNNFFNRFDPDFTQGSTCPIQLAFAFFNPSHIFDNAQGGPD  1301

Query  420   ALVDAFSRQ------------IAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRK  467
             +++   + Q            +  R+          L +A   I+  R+  L  +N +R 
Sbjct  1302  SILRGLTAQPHQDFDRFMVSGLTKRLFADPAGSDKGLDLAALNIQRGRDHGLPGYNAWRV  1361

Query  468   RFGMKPYTSFQELVGEKE---MAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI-E  523
               G+    SF EL  E         LE LY  +D ++ + G L E+  P+ + G +    
Sbjct  1362  LCGLPKANSFDELAFEIPDCFTRKRLENLYRHVDDIDVFVGGLAEESVPDGVVGPTFACL  1421

Query  524   IGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFNIVKTATLKKLVCLNT  571
             IG  F       N      +W   P  F        +K  +L +++C NT
Sbjct  1422  IGLQFQ------NLRKGDRFWFENPGQFTA-AQLAEIKKHSLARILCDNT  1464


>gb|AAH68379.1|  Mpx protein [Danio rerio]
Length=893

 GENE ID: 337514 mpx | myeloid-specific peroxidase [Danio rerio]
(Over 10 PubMed links)

 Score = 57.4 bits (137),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 65/256 (25%), Positives = 107/256 (41%), Gaps = 38/256 (14%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG-  353
            P L    TL++REHNR+   L   +PTW  E L+Q  R I+      +VI+EY+  + G 
Sbjct  394  PALNSLHTLFVREHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLPLIVGP  453

Query  354  --YFLQLKFDPELLFGVQFQYRN---RIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQF--  406
              Y   L   P     V     N     A  F HL     + P  F++     ++ QF  
Sbjct  454  DAYNRHLGPYPGYNENVDPTIANVFATAAFRFAHLT----IQPFIFRLDENYKNHPQFPS  509

Query  407  -----LFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL------------HVAVD  449
                  F +   V +  E  +D   R + GR       DH ++            H+A+D
Sbjct  510  VPLYEAFFSPWRVIF--EGGIDPVLRGLIGRPAKLNTQDHMLVNALRERLFAFTSHIALD  567

Query  450  V----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEF  502
            +    ++  R+  +  +N +R+  G+    + QEL   +   ++A +L ELYG  + ++ 
Sbjct  568  LASLNMQRGRDHAIPGYNAWRRFCGLSAPQNEQELAVVMNNTKLARKLIELYGTPENIDV  627

Query  503  YPGLLLEKCHPNSIFG  518
            + G + E   P    G
Sbjct  628  WLGGVAEPFAPGGRVG  643


>ref|XP_002205095.1|  hypothetical protein BRAFLDRAFT_67517 [Branchiostoma floridae]
 gb|EEA75402.1|  hypothetical protein BRAFLDRAFT_67517 [Branchiostoma floridae]
Length=1282

 GENE ID: 7226746 BRAFLDRAFT_67517 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 57.0 bits (136),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 60/134 (44%), Gaps = 7/134 (5%)

Query  227  VDLGHIYGDNLERQYQLRLFK--DGKLKYQ----VLDG-EMYPPSVEEAPVLMHYPRGIP  279
            +D  ++YG  L+    LR F   DG L+ Q    +  G ++ P   EE       P G  
Sbjct  396  IDASNVYGSTLDVAQSLRDFSTDDGLLRVQEGADISSGMDLLPFQDEEVSSCNQDPNGGD  455

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
                   G      +  L+   T W+REHNR+   LK+ +P W  EQ++Q  R I+  E 
Sbjct  456  IVPCFLAGDTRNNEVNTLIASHTTWVREHNRLARELKSINPHWDGEQIYQEARKIVGSEM  515

Query  340  IKIVIEEYVQQLSG  353
              I   EY+ ++ G
Sbjct  516  QHITYTEYLHKILG  529


>ref|XP_002205096.1|  hypothetical protein BRAFLDRAFT_67518 [Branchiostoma floridae]
 gb|EEA75403.1|  hypothetical protein BRAFLDRAFT_67518 [Branchiostoma floridae]
Length=462

 GENE ID: 7222363 BRAFLDRAFT_67518 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 57.0 bits (136),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 60/134 (44%), Gaps = 7/134 (5%)

Query  227  VDLGHIYGDNLERQYQLRLFK--DGKLKYQ----VLDG-EMYPPSVEEAPVLMHYPRGIP  279
            +D  ++YG  L+    LR     DG L+ Q    +  G ++ P   EE       P+G  
Sbjct  136  IDASNVYGSTLDVAQSLRDLSTDDGLLRVQEGADISSGLDLLPFQDEEVSSCNQDPKGGD  195

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
                   G      +  L+   T+WLREHNR+   LK+ +P W  E ++Q  R I+  E 
Sbjct  196  TIPCFLAGDVRSNEVNTLIASHTIWLREHNRIAKELKSINPRWDGETIYQEARKIVGAEM  255

Query  340  IKIVIEEYVQQLSG  353
              I   EY+ ++ G
Sbjct  256  QHITYTEYLPKILG  269


>ref|NP_001081848.1|  polysomal ribonuclease 1 [Xenopus laevis]
 gb|AAC94959.1|  polysomal ribonuclease 1 [Xenopus laevis]
Length=713

 GENE ID: 398084 PMR-1 | polysomal ribonuclease 1 [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 57.0 bits (136),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 74/322 (22%), Positives = 130/322 (40%), Gaps = 68/322 (21%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY  354
            PGL  + TL++R HN +   L+  +P W  E L+Q  R I+ G   KI  ++++  L G 
Sbjct  381  PGLTAFHTLFVRAHNNIAARLRELNPRWSGETLYQEARKIIGGILQKITYKDWLPLLLGS  440

Query  355  FLQL----------KFDPEL--LFGVQFQYRNRIAMEFNHLYH--WHPLMPDSFKVGSQE  400
             +              DP +  +F V F+  + +   F +     + PL P+       +
Sbjct  441  EMAAVLPAYRSYNESVDPRVSNVFTVVFRMGHTLIQPFIYRLADGYRPLGPEP------Q  494

Query  401  YSYEQFLFNTSMLV-DYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRE------  453
                +  FN+  +V + G++ L+      +A R    R        + VD +RE      
Sbjct  495  IPLHKTFFNSWRVVREGGIDPLLRGL---MANRAKLNRQN-----QLVVDELRERLFVLF  546

Query  454  --------------SREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGD  496
                           RE  L  +N +R+  G+   ++  EL   +  + +A +  +LYG 
Sbjct  547  KRIGLDLTAINMQRGREHGLPGYNAWRRFCGLSAPSNVNELAAVLNNRNLAEKFIKLYGS  606

Query  497  IDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPE------YWKPSTFG  550
             + ++ + G + E    N   G+          L  L+GN            Y +PS F 
Sbjct  607  PENIDIWVGGVAESLVRNGRIGK---------LLTCLIGNQFRRARDGDRFYYEQPSVFT  657

Query  551  GEVGFNIVKTATLKKLVCLNTK  572
             E   +I +  TL +++C NTK
Sbjct  658  NEQRASIER-VTLARVICDNTK  678


>ref|NP_001081108.1|  myeloperoxidase, peroxidase 2' [Xenopus laevis]
 gb|AAL55400.1|  peroxidase 2' [Xenopus laevis]
 gb|AAI69465.1|  Myeloperoxidase, peroxidase 2' [Xenopus laevis]
 gb|AAI69467.1|  Myeloperoxidase, peroxidase 2' [Xenopus laevis]
Length=725

 GENE ID: 394386 mpo-A | myeloperoxidase, peroxidase 2' [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 57.0 bits (136),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 90/389 (23%), Positives = 151/389 (38%), Gaps = 56/389 (14%)

Query  220  TKALGHGVDLGHIYGDNLERQYQLRL----FKDGKLKYQVLDGEMYPPSVEEAPVLMHYP  275
            ++  G   DL  +  +N   Q  L      F DG L Y    G M     E+  +L +  
Sbjct  311  SQVYGSTNDLARMLRNNTATQLGLMAVNTRFTDGGLPYLPF-GTMK----EDFCLLTNMS  365

Query  276  RGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLIL  335
             G+P       G       PGL  + T+++REHNR+   L+  +PTW  E LFQ  R I+
Sbjct  366  SGLP---CFLAGDARVSEQPGLTAFHTIFVREHNRIARELRRLNPTWTGEVLFQEARKIV  422

Query  336  IGETIKIVIEEYVQQLSGYFLQ------LKFDPELLFGVQFQYRNRIAMEFNHLYHWHPL  389
                 KI  ++Y+  L G  +         ++  +  G    +     M    +  +   
Sbjct  423  GAIEQKINYKDYLPLLLGSTMTRVLPRYTSYNDSVNPGAANVFSLIFRMGHTMIQPFIYR  482

Query  390  MPDSFKVGSQ--EYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVA  447
            + D ++  +           FNT  ++   +E  VD   R + G      N  + IL   
Sbjct  483  LVDGYRTSASLPPIPIHLTFFNTWRVI---LEGGVDPLLRGLMGN-QAKLNRQNQIL---  535

Query  448  VDVIRE--------------------SREMRLQPFNEYRKRFGM---KPYTSFQELVGEK  484
            VD +RE                     R+  L  +N +R+  G+   +  T    ++  +
Sbjct  536  VDELREHLFELFKRLGLDLGAINMQRGRDHGLPGYNAFRRFCGLSQPRNETELATVLRNR  595

Query  485  EMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI-EIGAPFSLKGLLGNPICSPEY  543
            ++A  L  LYG    ++ + G + E    N   GE +   IG  F  +   G+      Y
Sbjct  596  QLAQRLTSLYGTPQNIDIWLGAVAEPLVTNGRVGELLACLIGDQFR-RSRDGDRF---YY  651

Query  544  WKPSTFGGEVGFNIVKTATLKKLVCLNTK  572
             +PS F      + ++  TL ++VC NT+
Sbjct  652  ERPSIF-TPAQLSSIERVTLARMVCDNTR  679


>gb|AAI70068.1|  PMR-1 protein [Xenopus laevis]
 gb|AAI70070.1|  PMR-1 protein [Xenopus laevis]
Length=714

 GENE ID: 398084 PMR-1 | polysomal ribonuclease 1 [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 56.6 bits (135),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 74/322 (22%), Positives = 130/322 (40%), Gaps = 68/322 (21%)

Query  295  PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY  354
            PGL  + TL++R HN +   L+  +P W  E L+Q  R I+ G   KI  ++++  L G 
Sbjct  382  PGLTAFHTLFVRAHNNIAARLRELNPRWSGETLYQEARKIIGGILQKITYKDWLPLLLGS  441

Query  355  FLQL----------KFDPEL--LFGVQFQYRNRIAMEFNHLYH--WHPLMPDSFKVGSQE  400
             +              DP +  +F V F+  + +   F +     + PL P+       +
Sbjct  442  EMAAVLPAYRSYNESVDPRVSNVFTVVFRMGHTLIQPFIYRLADGYRPLGPEP------Q  495

Query  401  YSYEQFLFNTSMLV-DYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRE------  453
                +  FN+  +V + G++ L+      +A R    R        + VD +RE      
Sbjct  496  IPLHKTFFNSWRVVREGGIDPLLRGL---MANRAKLNRQN-----QLVVDELRERLFVLF  547

Query  454  --------------SREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGD  496
                           RE  L  +N +R+  G+   ++  EL   +  + +A +  +LYG 
Sbjct  548  KRIGLDLTAINMQRGREHGLPGYNAWRRFCGLSAPSNVNELAAVLNNRNLAEKFIKLYGS  607

Query  497  IDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPE------YWKPSTFG  550
             + ++ + G + E    N   G+          L  L+GN            Y +PS F 
Sbjct  608  PENIDIWVGGVAESLVRNGRIGK---------LLTCLIGNQFRRARDGDRFYYEQPSVFT  658

Query  551  GEVGFNIVKTATLKKLVCLNTK  572
             E   +I +  TL +++C NTK
Sbjct  659  NEQRASIER-VTLARVICDNTK  679


>gb|AAH82616.1|  Mpo-A protein [Xenopus laevis]
Length=738

 GENE ID: 394386 mpo-A | myeloperoxidase, peroxidase 2' [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 56.6 bits (135),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 90/389 (23%), Positives = 151/389 (38%), Gaps = 56/389 (14%)

Query  220  TKALGHGVDLGHIYGDNLERQYQLRL----FKDGKLKYQVLDGEMYPPSVEEAPVLMHYP  275
            ++  G   DL  +  +N   Q  L      F DG L Y    G M     E+  +L +  
Sbjct  324  SQVYGSTNDLARMLRNNTATQLGLMAVNTRFTDGGLPYLPF-GTMK----EDFCLLTNMS  378

Query  276  RGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLIL  335
             G+P       G       PGL  + T+++REHNR+   L+  +PTW  E LFQ  R I+
Sbjct  379  SGLP---CFLAGDARVSEQPGLTAFHTIFVREHNRIARELRRLNPTWTGEVLFQEARKIV  435

Query  336  IGETIKIVIEEYVQQLSGYFLQ------LKFDPELLFGVQFQYRNRIAMEFNHLYHWHPL  389
                 KI  ++Y+  L G  +         ++  +  G    +     M    +  +   
Sbjct  436  GAIEQKINYKDYLPLLLGSTMTRVLPRYTSYNDSVNPGAANVFSLIFRMGHTMIQPFIYR  495

Query  390  MPDSFKVGSQ--EYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVA  447
            + D ++  +           FNT  ++   +E  VD   R + G      N  + IL   
Sbjct  496  LVDGYRTSASLPPIPIHLTFFNTWRVI---LEGGVDPLLRGLMGN-QAKLNRQNQIL---  548

Query  448  VDVIRE--------------------SREMRLQPFNEYRKRFGM---KPYTSFQELVGEK  484
            VD +RE                     R+  L  +N +R+  G+   +  T    ++  +
Sbjct  549  VDELREHLFELFKRLGLDLGAINMQRGRDHGLPGYNAFRRFCGLSQPRNETELATVLRNR  608

Query  485  EMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI-EIGAPFSLKGLLGNPICSPEY  543
            ++A  L  LYG    ++ + G + E    N   GE +   IG  F  +   G+      Y
Sbjct  609  QLAQRLTSLYGTPQNIDIWLGAVAEPLVTNGRVGELLACLIGDQFR-RSRDGDRF---YY  664

Query  544  WKPSTFGGEVGFNIVKTATLKKLVCLNTK  572
             +PS F      + ++  TL ++VC NT+
Sbjct  665  ERPSIF-TPAQLSSIERVTLARMVCDNTR  692


>gb|AAH48774.1|  Mpo-A protein [Xenopus laevis]
 gb|AAI00161.1|  Mpo-A protein [Xenopus laevis]
 gb|AAI08480.1|  Mpo-A protein [Xenopus laevis]
 gb|AAI24839.1|  Mpo-A protein [Xenopus laevis]
 gb|AAI30063.1|  Mpo-A protein [Xenopus laevis]
Length=730

 GENE ID: 394386 mpo-A | myeloperoxidase, peroxidase 2' [Xenopus laevis]
(10 or fewer PubMed links)

 Score = 56.6 bits (135),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 90/389 (23%), Positives = 151/389 (38%), Gaps = 56/389 (14%)

Query  220  TKALGHGVDLGHIYGDNLERQYQLRL----FKDGKLKYQVLDGEMYPPSVEEAPVLMHYP  275
            ++  G   DL  +  +N   Q  L      F DG L Y    G M     E+  +L +  
Sbjct  316  SQVYGSTNDLARMLRNNTATQLGLMAVNTRFTDGGLPYLPF-GTMK----EDFCLLTNMS  370

Query  276  RGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLIL  335
             G+P       G       PGL  + T+++REHNR+   L+  +PTW  E LFQ  R I+
Sbjct  371  SGLP---CFLAGDARVSEQPGLTAFHTIFVREHNRIARELRRLNPTWTGEVLFQEARKIV  427

Query  336  IGETIKIVIEEYVQQLSGYFLQ------LKFDPELLFGVQFQYRNRIAMEFNHLYHWHPL  389
                 KI  ++Y+  L G  +         ++  +  G    +     M    +  +   
Sbjct  428  GAIEQKINYKDYLPLLLGSTMTRVLPRYTSYNDSVNPGAANVFSLIFRMGHTMIQPFIYR  487

Query  390  MPDSFKVGSQ--EYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVA  447
            + D ++  +           FNT  ++   +E  VD   R + G      N  + IL   
Sbjct  488  LVDGYRTSASLPPIPIHLTFFNTWRVI---LEGGVDPLLRGLMGN-QAKLNRQNQIL---  540

Query  448  VDVIRE--------------------SREMRLQPFNEYRKRFGM---KPYTSFQELVGEK  484
            VD +RE                     R+  L  +N +R+  G+   +  T    ++  +
Sbjct  541  VDELREHLFELFKRLGLDLGAINMQRGRDHGLPGYNAFRRFCGLSQPRNETELATVLRNR  600

Query  485  EMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI-EIGAPFSLKGLLGNPICSPEY  543
            ++A  L  LYG    ++ + G + E    N   GE +   IG  F  +   G+      Y
Sbjct  601  QLAQRLTSLYGTPQNIDIWLGAVAEPLVTNGRVGELLACLIGDQFR-RSRDGDRF---YY  656

Query  544  WKPSTFGGEVGFNIVKTATLKKLVCLNTK  572
             +PS F      + ++  TL ++VC NT+
Sbjct  657  ERPSIF-TPAQLSSIERVTLARMVCDNTR  684


>ref|XP_002242448.1|  hypothetical protein BRAFLDRAFT_246503 [Branchiostoma floridae]
 gb|EEA38030.1|  hypothetical protein BRAFLDRAFT_246503 [Branchiostoma floridae]
Length=437

 GENE ID: 7211899 BRAFLDRAFT_246503 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 56.6 bits (135),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 91/395 (23%), Positives = 156/395 (39%), Gaps = 73/395 (18%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDG------EMYPPSVEEAPVLMHYPRGIPP  280
            VD  ++YG N E    LR   DG+  + ++ G      E+ P ++++  +   + +G   
Sbjct  30   VDASNVYGQNEEDMAALR---DGRW-HPLMSGPPHLYKELLPEAMKDEFMCEGF-KGPDG  84

Query  281  QSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETI  340
                  G +     PG+    +L++REHNR+   L   +  W D+++F  TR I+     
Sbjct  85   YKCSQAGDKRVNENPGITSMHSLFMREHNRIARRLHNLNKQWDDDRVFMETRKIVGALLQ  144

Query  341  KIVIEEYVQQLSGYFLQLKFD-----PELLF---------GVQFQYRNRIAMEFNH--LY  384
            KI   EY+  + G     KFD     P+  F         G+ +   N  A  F H  + 
Sbjct  145  KIAYGEYLPLVLGPDYMTKFDLTLTKPDKYFQGYDKAVNPGI-YNVFNTAAYRFGHTMVQ  203

Query  385  HWHPLMPDSFKVGSQEYSYEQF--LFNTSMLVDY---GVEALVDAFSRQ---------IA  430
            +     P +F   SQ    +     FN S + D    G ++++   + Q         ++
Sbjct  204  NEFERYPPNFDPKSQHCPIKLAFSFFNPSYISDNDQGGPDSILRGLTTQPRQDFDRFMVS  263

Query  431  GRI--------GGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL--  480
            G          G G   D   L+     I+  R+  L  +N +R++ G      F +L  
Sbjct  264  GLTKSLLCEPQGSGHRSDLATLN-----IQRGRDHGLPGYNAWREKCGFPRAHRFVDLAP  318

Query  481  -VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESM-IEIGAPFS--LKGLLGN  536
             + +      L+ELY  +D ++ + G L E+  P  I G +    IG  F    KG    
Sbjct  319  QIPDVTTRERLQELYSHVDDIDLFVGGLAEQSVPGGIVGPTFACLIGMQFQDLRKG----  374

Query  537  PICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT  571
                  +W    F        +K  +L +++C NT
Sbjct  375  ----DRFW----FENSDQLAEIKKHSLARILCDNT  401


>emb|CAF98179.1|  unnamed protein product [Tetraodon nigroviridis]
Length=1379

 Score = 55.8 bits (133),  Expect = 6e-07, Method: Compositional matrix adjust.
 Identities = 75/340 (22%), Positives = 137/340 (40%), Gaps = 56/340 (16%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETI---------KIVIEE  346
             GL    T+W REHNR+   L   +P W  + ++   R I+  +           KI+ E 
Sbjct  893   GLTAMHTVWFREHNRIATELLRLNPHWDGDTIYHEARKIVGAQMQHVTYSHWLPKILGEA  952

Query  347   YVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLM----PDSFKVGSQEYS  402
              ++ +  Y     ++P +  G+ F      A  F H    +P++     D   +     S
Sbjct  953   GMRMMGSY---TGYNPNINAGI-FNAFATAAFRFGHTL-INPILYRLDEDFQPIPQGHVS  1007

Query  403   YEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHV  446
               +  F+   +V+   E  +D   R + G  G  R               +M H + L +
Sbjct  1008  LHRAFFSPFRIVN---EGGIDPLLRGLFGVAGKMRVSTQLLNTELTERLFSMAHAVALDL  1064

Query  447   AVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKE---MAAELEELYGDIDALEFY  503
             A   I+  R+  + P+N+YR    +    +F +L  E +   +  +++ LYG    ++ +
Sbjct  1065  AAMNIQRGRDHGIPPYNDYRTFCNLTSAQTFDDLRNEIKNPTVREKIQRLYGTPLNVDLF  1124

Query  504   PGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFNIVKTA  561
             P L+ E   P S  G +++ + A    +   G+      +W   P  F        +K A
Sbjct  1125  PALMAEDLVPGSRLGPTLMCLLATQFKRLRDGD-----RFWYENPGVF-TPAQLTQLKQA  1178

Query  562   TLKKLVCLNTKTCPYVS---FRVPD-----ASQDDGPAVE  593
             +L +++C N      V    FRV +     +S DD P ++
Sbjct  1179  SLARVLCDNGDNITRVQKDGFRVAEHPHGYSSCDDIPHID  1218


>ref|XP_002230791.1|  hypothetical protein BRAFLDRAFT_226591 [Branchiostoma floridae]
 gb|EEA49697.1|  hypothetical protein BRAFLDRAFT_226591 [Branchiostoma floridae]
Length=639

 GENE ID: 7241330 BRAFLDRAFT_226591 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 55.1 bits (131),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 57/245 (23%), Positives = 106/245 (43%), Gaps = 46/245 (18%)

Query  302  TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSG--------  353
            T+W+REHNR+   L+A +P W  ++L+Q  R I+  E   I  EEY+ ++ G        
Sbjct  300  TIWVREHNRLARQLRALNPHWSGDRLYQEARNIVAAEIAHITFEEYLPKILGPDGSRTPM  359

Query  354  --YFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHW--HPLMPDSFKVGSQEYSYEQFLFN  409
                  +++DPE    V    RN  AM    L      PL+    K   + Y  ++ + N
Sbjct  360  EEVGEYVEYDPE----VDPSLRNSFAMAAFRLNDAATAPLV----KRYDENYEEDRDIGN  411

Query  410  TSMLVDYGV------EALVDAFSRQIAG---RIGGGRNM-------------DHHILHVA  447
             ++   +        E+ +D   R + G   ++   RN+             DH  L +A
Sbjct  412  IALRHTFFAPWRIVKESGIDPLVRGLIGSPAKLATPRNVVHEELTQHLFGQPDHPGLDIA  471

Query  448  VDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEK---EMAAELEELYGDIDALEFYP  504
               ++  R+  +  +N +R    + P    Q  + ++   ++  +L ++YGD+  ++ + 
Sbjct  472  AITLQRGRDHGIPFYNNWRDLCEL-PLAGQQIFILKQIDADVRQKLSDVYGDVSNIDLWT  530

Query  505  GLLLE  509
              LLE
Sbjct  531  AGLLE  535


>ref|XP_419931.2|  PREDICTED: similar to mKIAA0230 protein [Gallus gallus]
Length=1456

 GENE ID: 421914 PXDN | peroxidasin homolog (Drosophila) [Gallus gallus]

 Score = 55.1 bits (131),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 58/261 (22%), Positives = 113/261 (43%), Gaps = 44/261 (16%)

Query  296   GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF  355
             GL    TLW REHNR+   L   +P W  + ++  TR I+  E   I    ++ ++ G  
Sbjct  959   GLTSIHTLWFREHNRIATELLKLNPHWDGDTIYHETRKIVGAEMQHITFSHWLPKIFGE-  1017

Query  356   LQLK-------FDPELLFGVQFQYRNRIAMEFNH------LYHWHPLMPDSFK-VGSQEY  401
             + +K       +DP +  G+  ++    A  F H      LY     + ++F+ +     
Sbjct  1018  VGMKMLGEYKGYDPSVNSGITNEFAT-AAFRFGHTLINPFLYR----LDENFEPIPQGHL  1072

Query  402   SYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILH-------------VAV  448
                +  F+   +V+   E  +D   R + G + G   +   +L+             VA+
Sbjct  1073  PLHKAFFSPFRIVN---EGGIDPLLRGLFG-VAGKMRVPSQLLNTELTERLFSMARTVAL  1128

Query  449   DV----IRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALE  501
             D+    I+  R+  + P++++R    +    +F++L  E    E+  +L  LYG    ++
Sbjct  1129  DLAAMNIQRGRDHGIPPYHDFRVYCNLSSAQTFEDLKNEIKNPEIREKLSRLYGSPLNID  1188

Query  502   FYPGLLLEKCHPNSIFGESMI  522
              +P L++E   P S  G +++
Sbjct  1189  LFPALMVEDLVPGSRLGPTLM  1209


>dbj|BAF33370.1|  Dual oxidase 1 [Danio rerio]
Length=1507

 GENE ID: 565097 duox1 | dual oxidase 1 [Danio rerio]

 Score = 53.9 bits (128),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 62/258 (24%), Positives = 103/258 (39%), Gaps = 44/258 (17%)

Query  286  VGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIE  345
              + +F +  G+     +W R HN +   L  EHP+W DE+LFQ  R  +I     I   
Sbjct  221  ANENIFSVTEGI-----IWFRYHNYLASKLHKEHPSWSDEELFQHARKRVIATFQNIAFY  275

Query  346  EYVQQLSGYFL------QLKFDPELLFGVQFQYRNRIAMEF------------NHLYHWH  387
            E++    G  +      Q   DP +   V+F+     A+ F            N   H+ 
Sbjct  276  EWLPAFLGTHVTSYPGYQKYVDPGI--SVEFE---AAAVRFGLTLAPPGVYKRNRTCHYR  330

Query  388  PLMPDSFKVGSQEYSYEQFL--FNTSMLVDYGVEALVDAFSRQIAGR-----IGGGRNMD  440
             ++ D             F    N  +     V+ L+   + QIA R     +   R+  
Sbjct  331  SVVNDDASKSPGLRLCNTFWNRNNPHLQSSLDVDELIMGMASQIAEREDNIIVEDLRDYM  390

Query  441  HHILHVAVD-----VIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEE  492
            +  L  +        I+  R+  L  +N+ R+   M P  SF+++   + + ++  EL +
Sbjct  391  YGPLRFSRSDAVALTIQRGRDFGLPSYNQIREALSMAPVNSFEDINPKLKDTKLLKELAD  450

Query  493  LY-GDIDALEFYPGLLLE  509
            LY  DI  LE + G LLE
Sbjct  451  LYENDISRLELFVGGLLE  468


>ref|XP_415715.2|  PREDICTED: similar to Myeloperoxidase precursor (MPO) [Gallus 
gallus]
Length=695

 GENE ID: 417466 LPO | lactoperoxidase [Gallus gallus]

 Score = 53.5 bits (127),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 74/321 (23%), Positives = 133/321 (41%), Gaps = 48/321 (14%)

Query  296  GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQL----  351
            GL    T++LREHNR+   L   +P W  E+L+Q +R I+   T  I   +Y+  L    
Sbjct  357  GLSALHTVFLREHNRLVTKLGKLNPHWDGEKLYQESRNIIAAMTQIITYRDYLPLLLAEE  416

Query  352  --------SGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFK-VGSQEYS  402
                    SGY   +      +F + F++ +     F         + DSF+ +GS  + 
Sbjct  417  TSKWIPLYSGYHETVDPTVSNVFSLAFRFGHTSVQPFVS------RLDDSFQPMGSLPHV  470

Query  403  YEQFLFNTS--MLVDYGVEALVDAFSRQIAGRIGGGR----NMDHHI--------LHVAV  448
                 F  S  ++++ G++ L+       A  +   +     + +H+        L +A 
Sbjct  471  PLHLTFCASWRIIMEGGIDPLIRGMVVDHAKLMKQNQMLIEELQNHLFEQTEIMGLDLAA  530

Query  449  DVIRESREMRLQPFNEYRKRFGM-KPYT--SFQELVGEKEMAAELEELYGDIDALEFYPG  505
              ++  R+  L  +N +R+  G+ +P T     E++G  E+  +L +LYG  D ++ + G
Sbjct  531  LNLQRGRDHGLPGYNAWRRFCGLSQPQTVDELSEVLGNTELTKKLMDLYGTPDNIDLWIG  590

Query  506  LLLEKCHPNSIFGESM-IEIGAPFSLKGLLGNPICSPEYW--KPSTFGGEVGFNIVKTAT  562
             + E   P    G  +   IG  F       N      +W   P  F  +    + K  +
Sbjct  591  AIAEPLIPRGRVGPLLACIIGTQFR------NLRDGDRFWWENPGVFTPQQLEELTKI-S  643

Query  563  LKKLVCLNT--KTCPYVSFRV  581
            + +++C NT  K  P   FR 
Sbjct  644  MSRVICDNTRIKKLPRDMFRA  664


>ref|XP_002220096.1|  hypothetical protein BRAFLDRAFT_225761 [Branchiostoma floridae]
 gb|EEA60475.1|  hypothetical protein BRAFLDRAFT_225761 [Branchiostoma floridae]
Length=565

 GENE ID: 7237763 BRAFLDRAFT_225761 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 53.1 bits (126),  Expect = 4e-06, Method: Compositional matrix adjust.
 Identities = 85/386 (22%), Positives = 145/386 (37%), Gaps = 63/386 (16%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAV  286
            VD  ++YG + +    LR     K        E+ P ++ E      +  G    SQ   
Sbjct  164  VDASNVYGSSEDEMSSLRSRNANK-------KELLPGAMTEDFECDEFT-GSETCSQ--A  213

Query  287  GQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEE  346
            G       PGL    T++LREHNR+   L   +P W D+++F  TR I+     KI   E
Sbjct  214  GDVRVNEQPGLTSMHTVFLREHNRIARGLCRLNPRWDDDRVFYETRKIIGALMQKITYGE  273

Query  347  YVQQLSGYFLQLKFDPELLF-GVQFQYRNRIAMEFNHLYH------WHPLMPDSFKVGSQ  399
            ++ ++ G          LL  G    Y   +     +++        H L+ +SF   + 
Sbjct  274  FLPRVIGPAAMAANQLRLLSNGFYRGYSASVNPTIFNVFATAAFRFGHSLVQNSFNRFAA  333

Query  400  EYSYEQ--------FLFNTSMLVDY---GVEALVDAFSRQ-----------------IAG  431
            +++             FN S + D    G ++++   + Q                  A 
Sbjct  334  DFTQGSTCPFELAFAFFNPSHIFDNAQGGPDSILRGLTAQPHQDFDRFMVSGLTKRLFAV  393

Query  432  RIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAA---  488
              G  R +D   L+     I+  R+  L  +N +R R G++      +L  E   A    
Sbjct  394  PAGSDRGLDLAALN-----IQRGRDHGLPGYNAWRARCGLRRAAKIGDLAREIPDATTRQ  448

Query  489  ELEELYGDIDALEFYPGLLLEKCHPNSIFGESM-IEIGAPFSLKGLLGNPICSPEYW--K  545
            +L  LY  +D ++ + G L E+     + G +    IG  F       N      +W   
Sbjct  449  KLGSLYSHVDDIDVFVGGLAEESVSGGVVGPTFACLIGMQFQ------NLRKGDRFWFEN  502

Query  546  PSTFGGEVGFNIVKTATLKKLVCLNT  571
            P  F        ++ A+L +++C NT
Sbjct  503  PGQF-SSAQLAEIRKASLARILCDNT  527


>ref|NP_001027595.1|  homologue of mammlian thyroid peroxidase [Ciona intestinalis]
 dbj|BAA76688.1|  homologue of mammlian thyroid peroxidase [Ciona intestinalis]
Length=909

 GENE ID: 445593 LOC445593 | homologue of mammlian thyroid peroxidase
[Ciona intestinalis]

 Score = 52.8 bits (125),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 81/334 (24%), Positives = 135/334 (40%), Gaps = 59/334 (17%)

Query  221  KALGHGVDLGHIYG--DNLERQYQLRLFKDGKLKYQVL--DGEM-YPPSVEEAPVLMHYP  275
             A+   VD   +YG  D+L R  +     DG +K   +  DG   Y P     P +    
Sbjct  314  NAVTSFVDASTVYGSTDSLNRILRNLTNDDGLMKVNTMFKDGNWDYLPFDPNNPCVQD--  371

Query  276  RGIPPQSQMAVGQEVFGLLPG-----LMLYA--TLWLREHNRVCDLLKAEHPTWGDEQLF  328
                P     V    F    G     L L A  T+W+REHNR+  +LK+ +P W  E ++
Sbjct  372  ----PFDASGVNIPCFHAGDGRVSEHLTLSAIHTVWVREHNRIARMLKSMNPHWSGEIIY  427

Query  329  QTTRLILIGETIKIV-IEEYVQQL------------SGYFLQLKFDPELLFG-VQFQY-R  373
            Q  R I +G   +IV  +EYV ++            +GY          +F    F++  
Sbjct  428  QEARKI-VGAYHQIVHWKEYVPKIIGPAGLRMMGNYTGYRENENPTVSNVFATAAFRFGH  486

Query  374  NRIAMEFNHL---YHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIA  430
              I+ +F  L   ++ HP  P           +E F     M+ + G++ ++     + A
Sbjct  487  ATISPQFRRLDENFNNHPQFPTILL-------HEAFFSPWRMIREGGMDPILRGLIGRPA  539

Query  431  GRIGGGRNMDHHIL--------HVAVDV----IRESREMRLQPFNEYRKRFGMKPYTSFQ  478
              I     M   +          VA+D+    ++  R+  L  +N++R+  G+    +F 
Sbjct  540  KLIKADEMMHEELRDKLFALQNQVALDLASLNLQRGRDHALPLYNDWREECGLARANNFS  599

Query  479  ELVGE---KEMAAELEELYGDIDALEFYPGLLLE  509
            +L GE   K +  +LE LYG    ++ +   L E
Sbjct  600  DLAGEIKDKAIRDKLEALYGHPGNIDLWLAGLSE  633


>ref|XP_002205011.1|  hypothetical protein BRAFLDRAFT_67523 [Branchiostoma floridae]
 gb|EEA75318.1|  hypothetical protein BRAFLDRAFT_67523 [Branchiostoma floridae]
Length=819

 GENE ID: 7217192 BRAFLDRAFT_67523 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score = 52.4 bits (124),  Expect = 6e-06, Method: Compositional matrix adjust.
 Identities = 59/303 (19%), Positives = 116/303 (38%), Gaps = 31/303 (10%)

Query  227  VDLGHIYGDNLERQYQLRLFK--DGKLKYQ----VLDG-EMYPPSVEEAPVLMHYPRGIP  279
            +D  ++YG        LR F   DG L+ Q    +  G ++ P   E        P G  
Sbjct  239  IDASNVYGSTFAFAQSLRDFSTDDGLLRVQEGADISSGMDLLPFQNEMVTSCNQDPNGGD  298

Query  280  PQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGET  339
                   G      +  L+   T+W+REHNR+   LK+ +P W  EQ++Q  R+  +G  
Sbjct  299  IVPCFLAGDGRVNEVNTLIASHTIWVREHNRLARELKSINPHWDGEQIYQEARMDQMG--  356

Query  340  IKIVIEEYVQQLSGYFLQLKFDPELLFG-VQFQYRNRIAMEFNHLYHWHPLMPDSFKVGS  398
                        +GY   +       F    F++ +     F   +  +        V  
Sbjct  357  ----------AYTGYNPNVNPSTRNEFATAAFRFGHAAIGAFVRRFDENYQEAAIGNVAL  406

Query  399  QEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHIL----HVAVDV----  450
             +  +  +       +D  +  L+  F++ +         +  ++      +A+D+    
Sbjct  407  SDAFFSPWRVFRESGIDPVIRGLIGGFAKLVTPTDVLHEELSQNLFKLRNQIALDLASLN  466

Query  451  IRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGLL  507
             +  R+  +  +N++R    +    SF +L GE    ++   L ++YGD++ ++ +P   
Sbjct  467  TQRGRDHGIPFYNDWRVFCNLTRAASFDDLSGEISNSDVRDALADVYGDVNNIDLWPAAQ  526

Query  508  LEK  510
            LE 
Sbjct  527  LED  529


>ref|XP_697836.3|  PREDICTED: similar to thyroid peroxidase [Danio rerio]
Length=679

 GENE ID: 569363 LOC569363 | similar to thyroid peroxidase [Danio rerio]

 Score = 52.0 bits (123),  Expect = 9e-06, Method: Compositional matrix adjust.
 Identities = 91/405 (22%), Positives = 161/405 (39%), Gaps = 71/405 (17%)

Query  227  VDLGHIYGDNLERQYQLRLFKDGKLKY--QVLD-GEMYPPSVEEAPVLMHYPRGIPPQSQ  283
            +D   +YG + E+Q  LR    G L    +  D G  + PSV + P       G P   +
Sbjct  264  IDASTVYGSSEEQQQILR-SSTGLLAVSEEFWDTGRPFLPSVPQRPSACLQQPGSPALLE  322

Query  284  MAV------GQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG  337
              V         V  +LP  +L+ TLW+REHNR+ +LL   +  WG ++++Q TR I+  
Sbjct  323  ARVECFAAGDSRVNEVLPLAVLH-TLWMREHNRLAELLAQINTHWGKQRVYQETRKIIGA  381

Query  338  ETIKIVIEEYVQQLSGYFLQLKF-----------DPEL--LFGVQFQYRNRIAMEFNHLY  384
                  + +Y+ ++ G     +F           DP +  +F          A  F H+ 
Sbjct  382  LHQIFTMRDYIPKVIGQESVNEFLGPYEGYNESVDPSVSNVFAT-------AAFRFGHVT  434

Query  385  HWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGV--EALVDAFSRQIAGRIGGGRNMDHH  442
               P +    +   ++  YE      S    + +  E  +D   R +       ++ +H 
Sbjct  435  -ISPYLRRLNQSFQEDERYETLTLQQSFFSPWRLVREGGLDPVLRALLSAPAVLQDQEHL  493

Query  443  I----------------LHVAVDVIRESREMRLQPFNEYRKRFGM---KPYTSFQELVGE  483
            +                L +A   ++  R+  L  +N +R   G+   +  +   +LVG 
Sbjct  494  MTEELTERLLVLNVPQNLDLAALNLQRGRDHGLPGYNAWRVFCGLDRVESRSDLLKLVGS  553

Query  484  KEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS---  540
             ++  E+ +LYG  D ++ + G LLE+         S    G  FS   L+G  +     
Sbjct  554  DDLVKEIMDLYGHPDNVDVWLGGLLERPL-------SGARTGPLFSC--LIGKQMKKLRD  604

Query  541  -PEYW--KPSTFGGEVGFNIVKTATLKKLVCLNT--KTCPYVSFR  580
               +W   P  F  E    + +T +L +++C N+     P  +FR
Sbjct  605  GDRFWWLNPGVFSAEQRHEL-QTHSLSRVICDNSGLMEVPLDAFR  648
Select All Get selected sequences
sp|P23219|PGH1_HUMAN Prostaglandin G/H synthase...

Distribution of 98 Blast Hits on the Query Sequence [?]
