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Heidelberg, 10 September 2018 First interactive model of human cell division Mitosis – how one cell divides and becomes two – is one of the fundamental processes of life. Researchers at EMBL's Ellenberg group have now produced the first interactive map of proteins that make our cells divide, allowing users to track exactly where and in which groups the proteins drive the division process forward. This first dynamic protein atlas of human cell division is published in Nature today.
General, 5 September 2018 €17 million fund to power European detection and imaging innovation pipeline The ATTRACT initiative will commit €17 million to funding 170 breakthrough detection and imaging ideas with market potential to help enable the creation of products, services, companies and jobs based on these technologies. The ATTRACT seed fund is open to researchers and entrepreneurs from organisations all over Europe. The call for proposals is already open and will collect breakthrough ideas until the 31st of October 2018.
Hinxton, 29 August 2018 PhenoMeNal: an online portal for metabolomics An international collaboration between EMBL’s European Bioinformatics Institute (EMBL-EBI) and 13 other partners has made large-scale metabolomics analyses easier with the launch of PhenoMeNal. This online portal allows researchers and clinicians to analyse large metabolomics datasets. For example, researchers can search for patterns in a patient’s data, and use the findings to improve the detection of disease and to help optimise treatment.
Heidelberg, 1 August 2018 Understanding soil through its microbiome Soil is full of life, essential for nutrient cycling and carbon storage. To better understand how it functions, an international research team led by Peer Bork and Falk Hildebrand at EMBL and the University of Tartu (Estonia) conducted the first global study of bacteria and fungi in soil. Their results show that bacteria and fungi are in constant competition for nutrients and produce an arsenal of antibiotics to gain an advantage over one another. Nature publishes the results on 1 August 2018.
Heidelberg, 12 July 2018 Parental chromosomes kept apart during embryo’s first division It was long thought that during an embryo’s first cell division, one spindle is responsible for segregating the embryo’s chromosomes into two cells. EMBL scientists from the Ellenberg group now show that there are actually two spindles, one for each set of parental chromosomes, meaning that the genetic information from each parent is kept apart throughout the first division. Science publishes the results – bound to change biology textbooks – on 12 July 2018.
Heidelberg, 6 July 2018 Melting bacteria to decipher antibiotic resistance With antibiotic resistance spreading worldwide, there is a strong need for new technologies to study bacteria. EMBL researchers from the Savitski and Typas groups have adapted an existing technique to study the melting behaviour of proteins so that it can be used for the study of bacteria. Molecular Systems Biology published their results – allowing researchers worldwide to start using the technique – on July 6.
Heidelberg, 4 July 2018 Combining antibiotics changes their effectiveness The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives. Depending on the bacterial species, some combinations stop antibiotics from working to their full potential whilst others begin to defeat antibiotic resistance, report EMBL researchers from the Typas group - and collaborators - in Nature on July 4.
Grenoble, 26 June 2018 Flu’s response to new drug explored The new influenza drug Xofluza was approved for clinical use in Japan in February 2018. Scientists from the Cusack group at EMBL Grenoble have now investigated the drug’s mode of action in detail, and uncovered possible mechanisms by which viral resistance to it could emerge. Scientific Reports published the results of this collaboration between scientists from EMBL and Japanese pharmaceutical company Shionogi on 25 June.
Heidelberg, 22 June 2018 Miniature testing of drug pairs on tumour biopsies Combinations of cancer drugs can be quickly and cheaply tested on tumour cells using a novel device developed by EMBL scientists from the Merten group. The research, reported in Nature Communications on June 22, marks the latest advancement in the field of personalised medicine.
Barcelona, 20 June 2018 New theory deepens understanding of Turing patterns A team of researchers at EMBL Barcelona's Sharpe group have expanded Alan Turing’s seminal theory on how patterns are created in biological systems. This work, published 20 June in Physical Review X, may answer whether nature’s patterns are governed by Turing’s mathematical model and could have applications in tissue engineering.
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