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Heidelberg, 15 May 2017 Cell changes drive breast cancer relapse Relapse is now the main cause of death for breast cancer patients. Researchers in the Jechlinger group at EMBL have found that, in mice, the tumour cells that survive therapy and eventually cause a relapse have specific traits that distinguish them from healthy cells. In a study published today in the Journal of Clinical Investigation, the scientists revealed that two of these traits could be promising targets for treatments to reduce tumour recurrence in breast cancer patients.
Heidelberg, 8 May 2017 EMBL spin-off company Luxendo acquired by Bruker In a deal signed today, EMBL spin-off company Luxendo was acquired by the Bruker Corporation. Based in Heidelberg, Germany, Luxendo develops and commercialises microscopes that use the Single Plane Illumination Microscopy (SPIM) technique developed by EMBL researchers.
Monterotondo, 25 April 2017 Developing embryos found to use ancient viral DNA DNA from viruses that once infected our ancestors millions of years ago have remained in our genome to this day. In a study published today in eLife, the Hackett lab at EMBL found that activation of one class of these ancient viral sequences is critical for early mouse embryo development, and identified the protein involved in regulating them.
Barcelona, 10 April 2017 EMBL to open new site in Barcelona At a ceremony in Barcelona today, EMBL and the Spanish government signed an agreement for a new EMBL site to be hosted in the city. EMBL Barcelona will be located on the campus of the Barcelona Biomedical Research Park (PRBB), and researchers at the site will explore how tissues and organs function and develop, and how preventing failures in those processes may help to tackle disease. Alongside cutting-edge research, the site will house state-of-the-art imaging facilities, making pioneering technologies available to scientists worldwide.
Heidelberg, London, 16 February 2017 GSK and EMBL form a new strategic collaboration to enhance understanding of disease and drug mechanisms EMBL and GSK have signed a collaboration agreement to leverage the skills of both organisations to enhance understanding of disease and drug mechanisms and advance early drug discovery. EMBL and GSK will jointly develop and apply cutting edge technologies that will allow the comprehensive characterisation of how a potential new medicine will interact with human biology on a molecular, cellular and organ level to better predict its actions in the human body.
Monterotondo, 9 January 2017 Neural connection keeps instincts in check From fighting the urge to hit someone to resisting the temptation to run off stage instead of giving that public speech, we are often confronted with situations where we have to curb our instincts. Scientists at EMBL have traced exactly which neuronal projections prevent social animals like us from acting out such impulses. The study, published online today in Nature Neuroscience, could have implications for schizophrenia and mood disorders like depression.
- Corriere della Sera , 10 January 2017 Meccanismo in cervello soffoca istinti
- La Repubblica , 10 January 2017 Dalla paura al sesso, ecco come il cervello soffoca gli istinti
Grenoble, 21 December 2016 How flu steals your RNA New work by the Cusack group at EMBL published this week in Nature explains how the influenza virus’ transcription machine interacts with its counterpart in the host cell, offering new possibilities for anti-viral drug design. “We’ve uncovered the details of a mechanism that’s common to all influenza strains, so we believe this could be a good target for developing new flu drugs,” says Stephen Cusack.
Monterotondo, 13 December 2016 Study offers approach to treating pain For many patients with chronic pain, any light touch – even just their clothes touching their skin – can be agony. The Heppenstall lab at EMBL and colleagues have found a possible new avenue for producing painkillers that specifically treat this kind of pain. In a study published online today in eLife, they discovered how the stiffness of our nerve cells influences sensitivity to touch and pain.
Grenoble, 23 November 2016 Toxoplasma’s balancing act explained The parasite Toxoplasma gondii is a silent success. It infects up to 95% of people in many regions of the world, and most of them never know it, due to the parasite’s artful manipulation of its host’s immune response. Toxoplasma keeps the immune response low enough so that it can thrive, but high enough so that its human hosts generally live healthy lives and can incubate parasites. Matthew Bowler and colleagues at EMBL and the Institute for Advanced Biosciences (IAB, an INSERM - CNRS - Université Grenoble-Alpes research centre) have uncovered one of the ways it maintains this balance, in a paper published today in Structure.
Heidelberg, 3 November 2016 Picture Release | Spiral growth This flower-like image shows a plant that is not developing quite right. It comes from a study in which scientists at EMBL and the University of Sydney unearthed the molecular feedback loop that creates the spiral pattern of leaves around a stem. The work is published today in Current Biology.
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