EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Personal Assistant
Kirsi Heerde
Room: 209-212
Tel: +49 6221 387- 8201
Fax: +49 6221 387- 8211
E-mail: dg-office@embl.org

Biography

  • PhD 1979, University of Leeds, UK.
    Postdoctoral work at the Friedrich Miescher Institute and the Biocenter, Basel, Switzerland.
    Group Leader at EMBL since 1985.
    Programme Coordinator since 1990.
    Scientific Director of EMBL 1999-2005.
    Director General since 2005.

Publications

Total: 222 publication(s)

1987

Hamm J, Dathan N, Kazmaier M, Mattaj IW. (1987)

Functional roles of U snRNP components

Mol Biol Rep 12(3):174-175. doi: 10.1007/BF00356885
doi

Tebb G, Kazmaier M, Parry H, Dathan N, Mattaj IW. (1987)

Transcription of Xenopus U snRNA genes

Mol Biol Rep 12(3):147-149. doi: 10.1007/BF00356870
doi

Tebb G, Mattaj IW, Keller W, Bohmann D. (1987)

Characterization of an Enhancer-Binding Protein

In: Reznikoff WS, RNA Polymerase and the Control of Transcription, vol 16. Steenbock Symposium. pp 421-426.


1986

Ciliberto G, Dathan N, Frank R, Philipson L, Mattaj IW. (1986)

Formation of the 3' end on U snRNAs requires at least three sequence elements

EMBO J 5(11):2931-2937.
Europe PMC

Mattaj IW. (1986)

Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding

Cell 46(6):905-911. doi: 10.1016/0092-8674(86)90072-3
Europe PMC | doi

Mattaj IW, Habets WJ, van Venrooij WJ. (1986)

Monospecific antibodies reveal details of U2 snRNP structure and interaction between U1 and U2 snRNPs

EMBO J 5(5):997-1002.
Europe PMC

Mattaj IW. (1986)

The role of RNA-protein interactions in intracellular targeting

In: Peters R, Trendelenburg M, Nucleocytoplasmic Transport. Nucleocytoplasmic Transport edn. Springer Verlag, Berlin Heidelberg. pp 275-285.


1985

De Robertis EM, Fritz A, Goetz J, Martin G, Mattaj IW, Salo E, Smith GD, Wright C, Zeller R. (1985)

The Xenopus homeo boxes

Cold Spring Harb Symp Quant Biol 50:271-275.
Europe PMC

Mattaj IW, De Robertis EM. (1985)

Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

Cell 40(1):111-118. doi: 10.1016/0092-8674(85)90314-9
Europe PMC | doi

Mattaj IW, Lienhard S, Jiricny J, De Robertis EM. (1985)

An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes

Nature 316(6024):163-167. doi: 10.1038/316163a0
Europe PMC | doi

Mattaj IW, Zeller R, Carrasco AE, Jamrich M, Lienhard S, De Robertis EM. (1985)

U snRNA gene families in Xenopus laevis

In: Maclean N, Oxford Surveys on Eukaryotic Genes, vol 2. Oxford University Press. pp 121-140.
Europe PMC


1984

Zeller R, Carri MT, Mattaj IW, De Robertis EM. (1984)

Xenopus laevis U1 snRNA genes: characterisation of transcriptionally active genes reveals major and minor repeated gene families

EMBO J. 3(5):1075-1081.
Europe PMC

Brack C, Mattaj IW, Gautschi J, Cammisuli S. (1984)

Cyclosporin A is a differential inhibitor of eukaryotic RNA polymerases

Exp. Cell Res. 151(2):314-321. doi: 10.1016/0014-4827(84)90382-3
Europe PMC | doi

Mattaj IW. (1984)

SnRNAs: from gene architecture to RNA processing

Trends Biochem Sci 9(10):435-437. doi: 10.1016/0968-0004(84)90151-8
doi


1983

Mattaj IW, Lienhard S, Zeller R, DeRobertis EM. (1983)

Nuclear exclusion of transcription factor IIIA and the 42s particle transfer RNA-binding protein in Xenopus oocytes: a possible mechanism for gene control?

J. Cell Biol. 97(4):1261-1265. doi: 10.1083/jcb.97.4.1261
Europe PMC | doi

Mattaj IW, Zeller R. (1983)

Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes

EMBO J. 2(11):1883-1891.
Europe PMC

De Robertis EM, Zeller R, Carrasco A, Mattaj IW. (1983)

Nucleocytoplasmic transport of macromolecules in frog oocytes and embryos

In: Wyllie CC, McLaren A, British Society for Developmental Biology Symposia. Cambridge University Press. pp 377-391.

Geiser M, Mattaj IW, Wilks AF, Seldran M, Jost JP. (1983)

Structure and sequence of the promoter area and of a 5' upstream demethylation site of the estrogen-regulated chicken vitellogenin-II gene

J Biol Chem 258(14):9024-9030.
Europe PMC


1982

Mattaj IW, McPherson MJ, Wootton JC. (1982)

Localisation of a strongly conserved section of coding sequence in glutamate dehydrogenase genes

FEBS Lett. 147(1):21-25. doi: 10.1016/0014-5793(82)81003-x
Europe PMC | doi

Mattaj IW, Mackenzie A, Jost JP. (1982)

Cloning in a cosmid vector of complete 37 kb and 25 kb ribosomal DNA repeat units from the chicken

Biochim. Biophys. Acta 698(2):204-210. doi: 10.1016/0167-4781(82)90136-1
Europe PMC | doi

Wilks AF, Cozens PJ, Mattaj IW, Jost JP. (1982)

Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene

Proc Natl Acad Sci USA 79(14):4252-4255. doi: 10.1073/pnas.79.14.4252
Europe PMC | doi


1981

Wilks A, Cato AC, Cozens PJ, Mattaj IW, Jost JP. (1981)

Isolation and fine structure organisation of an avian vitellogenin gene coding for the major estrogen-inducible mRNA

Gene 16(1-3):249-259. doi: 10.1016/0378-1119(81)90081-0
Europe PMC | doi