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Silica-based solid-phase extraction of cross-linked nucleic acid-bound proteins.

Life Sci Alliance 1(3) doi: 10.26508/lsa.201800088
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Nat. Struct. Mol. Biol. 25(7) doi: 10.1038/s41594-018-0081-1
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Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A. (2018)

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

Nat Commun 9(1) doi: 10.1038/s41467-018-04092-0
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Hentze MW, Castello A, Schwarzl T, Preiss T. (2018)

A brave new world of RNA-binding proteins.

Nat Rev Mol Cell Biol 19(5) doi: 10.1038/nrm.2017.130
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Castello A, Frese CK, Fischer B, Järvelin AI, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW. (2017)

Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap.

Nat Protoc 12(12):2447-2464. doi: 10.1038/nprot.2017.106
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Quintas A, Pérez-Núñez D, Sánchez EG, Nogal ML, Hentze MW, Castelló A, Revilla Y. (2017)

Characterization of the African swine fever virus decapping enzyme during infection.

J. Virol. 91(24) doi: 10.1128/JVI.00990-17
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Costa da Silva M, Breckwoldt MO, Vinchi F, Correia MP, Stojanovic A, Thielmann CM, Meister M, Muley T, Warth A, Platten M, Hentze MW, Cerwenka A, Muckenthaler MU. (2017)

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages.

Front Immunol 8 doi: 10.3389/fimmu.2017.01479
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Luscieti S, Galy B, Gutierrez L, Reinke M, Couso J, Shvartsman M, Di Pascale A, Witke W, Hentze MW, Pilo Boyl P, Sanchez M. (2017)

The actin binding protein profilin 2 is a novel regulator of iron homeostasis.

Blood 130(17) doi: 10.1182/blood-2016-11754382
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Neu-Yilik G, Raimondeau E, Eliseev B, Yeramala L, Amthor B, Deniaud A, Huard K, Kerschgens K, Hentze MW, Schaffitzel C, Kulozik AE. (2017)

Dual function of UPF3B in early and late translation termination.

EMBO J 36(20) doi: 10.15252/embj.201797079
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Haberman N, Huppertz I, Attig J, König J, Wang Z, Hauer C, Hentze MW, Kulozik AE, Le Hir H, Curk T, Sibley CR, Zarnack K, Ule J. (2017)

Erratum to: Insights into the design and interpretation of iCLIP experiments.

Genome Biol 18(1) doi: 10.1186/s13059-017-1294-z
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da Silva AR, Neves J, Mleczko-Sanecka K, Tandon A, Sauer SW, Hentze MW, Muckenthaler MU. (2017)

Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin.

J. Mol. Med. 95(8):851-860. doi: 10.1007/s00109-017-1551-3
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Rogell BM, Fischer B, Rettel M, Krijgsveld J, Castello A, Hentze MW. (2017)

Specific RNP capture with antisense LNA/DNA mixmers.

RNA 23(8) doi: 10.1261/rna.060798.117
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Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, Jordan J, Bauersachs J, Hentze MW, Wollert KC, Kempf T. (2017)

Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.

Eur. Heart J. 38(5):362-372. doi: 10.1093/eurheartj/ehw333
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Muckenthaler MU, Rivella S, Hentze MW, Galy B. (2017)

A Red Carpet for Iron Metabolism.

Cell 168(3):344-361. doi: 10.1016/j.cell.2016.12.034
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Haberman N, Huppertz I, Attig J, König J, Wang Z, Hauer C, Hentze MW, Kulozik AE, Le Hir H, Curk T, Sibley CR, Zarnack K, Ule J. (2017)

Insights into the design and interpretation of iCLIP experiments.

Genome Biol. 18(1):7. doi: 10.1186/s13059-016-1130-x
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Reichel M, Liao Y, Rettel M, Ragan C, Evers M, Alleaume AM, Horos R, Hentze MW, Preiss T, Millar AA. (2016)

In planta determination of the mRNA-binding proteome of Arabidopsis etiolated seedlings.

Plant Cell 28(10) doi: 10.1105/tpc.16.00562
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Castello A, Fischer B, Frese CK, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW. (2016)

Comprehensive Identification of RNA-Binding Domains in Human Cells.

Mol. Cell 63(4):696-710. doi: 10.1016/j.molcel.2016.06.029
Europe PMC | doi

Hauer C, Sieber J, Schwarzl T, Hollerer I, Curk T, Alleaume AM, Hentze MW, Kulozik AE. (2016)

Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins.

Cell Rep 16(6):1588-1603. doi: 10.1016/j.celrep.2016.06.096
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Liepelt A, Naarmann-de Vries IS, Simons N, Eichelbaum K, Foehr S, Archer SK, Castello A, Usadel B, Krijgsveld J, Preiss T, Marx G, Hentze MW, Ostareck DH, Ostareck-Lederer A. (2016)

Identification of RNA-binding proteins in macrophages by interactome capture.

Mol. Cell Proteomics 15(8):2699-2714. doi: 10.1074/mcp.M115.056564
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Liao Y, Castello A, Fischer B, Leicht S, Föehr S, Frese C, Ragan C, Kurscheid S, Pagler E, Yang H, Krijgsveld J, Hentze MW, Preiss T. (2016)

The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease

Cell Rep 16(5):1456-1469. doi: 10.1016/j.celrep.2016.06.084
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Hollerer I, Curk T, Haase B, Benes V, Hauer C, Neu-Yilik G, Bhuvanagiri M, Hentze MW, Kulozik AE. (2016)

The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion.

RNA 22(9):1441-1453. doi: 10.1261/rna.055657.115
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Sysoev VO, Fischer B, Frese CK, Gupta I, Krijgsveld J, Hentze MW, Castello A, Ephrussi A. (2016)

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila.

Nat Commun 7:12128. doi: 10.1038/ncomms12128
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Kovac S, Böser P, Cui Y, Ferring-Appel D, Casarrubea D, Huang L, Fung E, Popp A, Mueller BK, Hentze MW. (2016)

Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels.

Haematologica 101(5):e173-176. doi: 10.3324/haematol.2015.140772
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Sieber J, Hauer C, Bhuvanagiri M, Leicht S, Krijgsveld J, Neu-Yilik G, Hentze MW, Kulozik AE. (2016)

Proteomic analysis reveals branch-specific regulation of the unfolded protein response by nonsense-mediated mRNA decay.

Mol. Cell Proteomics 15(5) doi: 10.1074/mcp.M115.054056
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Theurl M, Song D, Clark E, Sterling J, Grieco S, Altamura S, Galy B, Hentze M, Muckenthaler MU, Dunaief JL. (2016)

Mice with hepcidin-resistant ferroportin accumulate iron in the retina.

FASEB J. 30(2):813-823. doi: 10.1096/fj.15-276758
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Gebauer F, Hentze MW. (2016)

IRES unplugged.

Science 351(6270) doi: 10.1126/science.aad8540
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Castello A, Horos R, Strein C, Fischer B, Eichelbaum K, Steinmetz LM, Krijgsveld J, Hentze MW. (2016)

Comprehensive Identification of RNA-Binding Proteins by RNA Interactome Capture.

Methods Mol. Biol. 1358:131-139. doi: 10.1007/978-1-4939-3067-8_8
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Siegert I, Schödel J, Nairz M, Schatz V, Dettmer K, Dick C, Kalucka J, Franke K, Ehrenschwender M, Schley G, Beneke A, Sutter J, Moll M, Hellerbrand C, Wielockx B, Katschinski DM, Lang R, Galy B, Hentze MW, Koivunen P, Oefner PJ, Bogdan C, Weiss G, Willam C, Jantsch J. (2015)

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.

Cell Rep 13(10):2048-2055. doi: 10.1016/j.celrep.2015.11.005
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Popow J, Alleaume AM, Curk T, Schwarzl T, Sauer S, Hentze MW. (2015)

FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation.

RNA 21(11) doi: 10.1261/rna.052365.115
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Beckmann BM, Horos R, Fischer B, Castello A, Eichelbaum K, Alleaume AM, Schwarzl T, Curk T, Foehr S, Huber W, Krijgsveld J, Hentze MW. (2015)

The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs.

Nat Commun 6 doi: 10.1038/ncomms10127
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Castello A, Hentze MW, Preiss T. (2015)

Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins.

Trends Endocrinol. Metab. 26(12):746-757. doi: 10.1016/j.tem.2015.09.012
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Nairz M, Ferring-Appel D, Casarrubea D, Sonnweber T, Viatte L, Schroll A, Haschka D, Fang FC, Hentze MW, Weiss G, Galy B. (2015)

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

Cell Host Microbe 18(2):254-261. doi: 10.1016/j.chom.2015.06.017
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Hauer C, Curk T, Anders S, Schwarzl T, Alleaume AM, Sieber J, Hollerer I, Bhuvanagiri M, Huber W, Hentze MW, Kulozik AE. (2015)

Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP.

Nat Commun 6:7921. doi: 10.1038/ncomms8921
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Guida C, Altamura S, Klein FA, Galy B, Boutros M, Ulmer AJ, Hentze MW, Muckenthaler MU. (2015)

A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia.

Blood 125(14):2265-2275. doi: 10.1182/blood-2014-08-595256
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Martelli A, Schmucker S, Reutenauer L, Mathieu JR, Peyssonnaux C, Karim Z, Puy H, Galy B, Hentze MW, Puccio H. (2015)

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.

Cell Metab. 21(2):311-322. doi: 10.1016/j.cmet.2015.01.010
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Bhuvanagiri M, Lewis J, Putzker K, Becker JP, Leicht S, Krijgsveld J, Batra R, Turnwald B, Jovanovic B, Hauer C, Sieber J, Hentze MW, Kulozik AE. (2014)

5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.

EMBO Mol Med 6(12):1509-1639. doi: 10.15252/emmm.201404461
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Kramer K, Sachsenberg T, Beckmann BM, Qamar S, Boon KL, Hentze MW, Kohlbacher O, Urlaub H. (2014)

Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins.

Nat. Methods 11(10):1064-1070. doi: 10.1038/nmeth.3092
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Altamura S, Kessler R, Gröne HJ, Gretz N, Hentze MW, Galy B, Muckenthaler MU. (2014)

Resistance of Ferroportin to Hepcidin Binding causes Exocrine Pancreatic Failure and Fatal Iron Overload

Cell Metab. 20(2):359-367. doi: 10.1016/j.cmet.2014.07.007
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Strein C, Alleaume AM, Rothbauer U, Hentze MW, Castello A. (2014)

A versatile assay for RNA-binding proteins in living cells

RNA 20(5):721-731. doi: 10.1261/rna.043562.113
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Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, Wittig JG, Chen W, Lu W, Galy B, Schlaeger TM, Hentze MW, Ward DM, Kaplan J, Eisenstein RS, Peters LL, Paw BH. (2014)

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria

J. Biol. Chem. 289(11):7835-7843. doi: 10.1074/jbc.m114.547778
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Mleczko-Sanecka K, Roche F, da Silva AR, Call D, D'Alessio F, Ragab A, Lapinski PE, Ummanni R, Korf U, Oakes C, Damm G, D'Alessandro LA, Klingmüller U, King PD, Boutros M, Hentze MW, Muckenthaler MU. (2014)

Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.

Blood 123(10):1574-1585. doi: 10.1182/blood-2013-07-515957
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Hollerer I, Grund K, Hentze MW, Kulozik AE. (2014)

mRNA 3'end processing: A tale of the tail reaches the clinic

EMBO Mol Med 6(1):16-26. doi: 10.1002/emmm.201303300
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Altamura S, Grone HJ, Kessler R, Galy B, Hentze MW, Muckenthaler MU. (2013)

In Vivo Disruption Of The Hepcidin-Ferroportin Regulatory Circuitry Causes Fatal Systemic and Exocrine Pancreatic Iron Overload

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Danckwardt S, Hentze MW, Kulozik AE. (2013)

Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond

J. Mol. Med. 91(11):1257-1271. doi: 10.1007/s00109-013-1074-5
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Kwon SC, Yi H, Eichelbaum K, Föhr S, Fischer B, You KT, Castello A, Krijgsveld J, Hentze MW, Kim VN. (2013)

The RNA-binding protein repertoire of embryonic stem cells

Nat. Struct. Mol. Biol. 20(9):1122-1130. doi: 10.1038/nsmb.2638
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Casarrubea D, Viatte L, Hallas T, Vasanthakumar A, Eisenstein RS, Schümann K, Hentze MW, Galy B. (2013)

Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function

J. Mol. Med. 91(7):871-881. doi: 10.1007/s00109-013-1008-2
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Hentze MW, Izaurralde E. (2013)

Making sense of nonsense

Nat. Struct. Mol. Biol. 20(6):651-653. doi: 10.1038/nsmb.2601
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Castello A, Fischer B, Hentze MW, Preiss T. (2013)

RNA-binding proteins in Mendelian disease

Trends Genet. 29(5):318-327. doi: 10.1016/j.tig.2013.01.004
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Galy B, Ferring-Appel D, Becker C, Gretz N, Grone HJ, Schumann K, Hentze MW. (2013)

IRON REGULATORY PROTEINS SECURE EFFICIENT DIETARY IRON INTAKE AND DEFINE A BASAL SET POINT FOR THE REGULATION OF IRON ABSORPTION

AM J HEMATOL 88(5):E28.

Guida C, Altamura S, Klein F, Boutros M, Hentze MW, Martina UM. (2013)

IDENTIFICATION OF NOVEL REGULATORS OF FERROPORTIN EXPRESSION

AM J HEMATOL 88(5):E128-E129.

Nairz M, Ferring-Appel D, Schroll A, Hentze MW, Weiss G, Galy B. (2013)

IRON REGULATORY PROTEINS MEDIATE MACROPHAGE INNATE IMMUNITY AGAINST SALMONELLA

AM J HEMATOL 88(5):E26.

Hentze MW, Preiss T. (2013)

Circular RNAs: splicing's enigma variations

EMBO J. 32(7):923-925. doi: 10.1038/emboj.2013.53
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Castello A, Horos R, Strein C, Fischer B, Eichelbaum K, Steinmetz LM, Krijgsveld J, Hentze MW. (2013)

System-wide identification of RNA-binding proteins by interactome capture

Nat Protoc 8(3):491-500. doi: 10.1038/nprot.2013.020
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Galy B, Ferring-Appel D, Becker C, Gretz N, Gröne HJ, Schümann K, Hentze MW. (2013)

Iron regulatory proteins control a mucosal block to intestinal iron absorption

Cell Rep 3(3):844-857. doi: 10.1016/j.celrep.2013.02.026
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Anderson SA, Nizzi CP, Chang YI, Deck KM, Schmidt PJ, Galy B, Damnernsawad A, Broman AT, Kendziorski C, Hentze MW, Fleming MD, Zhang J, Eisenstein RS. (2013)

The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption

Cell Metab. 17(2):282-290. doi: 10.1016/j.cmet.2013.01.007
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D'Alessio F, Hentze MW, Muckenthaler MU. (2012)

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

J. Hepatol. 57(5):1052-1060. doi: 10.1016/j.jhep.2012.06.015
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Casanova CM, Sehr P, Putzker K, Hentze MW, Neumann B, Duncan KE, Thoma C. (2012)

Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation

PLoS ONE 7(9):e45943. doi: 10.1371/journal.pone.0045943
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Gebauer F, Preiss T, Hentze MW. (2012)

From cis-regulatory elements to complex RNPs and back

Cold Spring Harb Perspect Biol 4(7):a012245. doi: 10.1101/cshperspect.a012245
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Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW. (2012)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

Cell 149(6):1393-1406. doi: 10.1016/j.cell.2012.04.031
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Moretti F, Kaiser C, Zdanowicz-Specht A, Hentze MW. (2012)

PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding

Nat. Struct. Mol. Biol. 19(6):603-608. doi: 10.1038/nsmb.2309
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Sanchez M, Galy B, Schwanhaeusser B, Blake J, Bähr-Ivacevic T, Benes V, Selbach M, Muckenthaler MU, Hentze MW. (2011)

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins

Blood 118(22):e168-79. doi: 10.1182/blood-2011-04-343541
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Medenbach J, Seiler M, Hentze MW. (2011)

Translational control via protein-regulated upstream open reading frames

Cell 145(6):902-913. doi: 10.1016/j.cell.2011.05.005
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Neu-Yilik G, Amthor B, Gehring NH, Bahri S, Paidassi H, Hentze MW, Kulozik AE. (2011)

Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon

RNA 17(5):843-854. doi: 10.1261/rna.2401811
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Rakotondrafara AM, Hentze MW. (2011)

An efficient factor-depleted mammalian in vitro translation system

Nat Protoc 6(5):563-571. doi: 10.1038/nprot.2011.314
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Castoldi M, Vujic Spasic M, Altamura S, Elmén J, Lindow M, Kiss J, Stolte J, Sparla R, D'Alessandro LA, Klingmüller U, Fleming RE, Longerich T, Gröne HJ, Benes V, Kauppinen S, Hentze MW, Muckenthaler MU. (2011)

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

J. Clin. Invest. 121(4):1386-1396. doi: 10.1172/jci44883
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Danckwardt S, Gantzert AS, Macher-Goeppinger S, Probst HC, Gentzel M, Wilm M, Gröne HJ, Schirmacher P, Hentze MW, Kulozik AE. (2011)

p38 MAPK controls prothrombin expression by regulated RNA 3' end processing

Mol. Cell 41(3):298-310. doi: 10.1016/j.molcel.2010.12.032
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Moretti F, Thermann R, Hentze MW. (2010)

Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame

RNA 16(12):2493-2502. doi: 10.1261/rna.2384610
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Bhuvanagiri M, Schlitter AM, Hentze MW, Kulozik AE. (2010)

NMD: RNA biology meets human genetic medicine

Biochem. J. 430(3):365-377. doi: 10.1042/bj20100699
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Cohen LA, Gutierrez L, Weiss A, Leichtmann-Bardoogo Y, Zhang DL, Crooks DR, Sougrat R, Morgenstern A, Galy B, Hentze MW, Lazaro FJ, Rouault TA, Meyron-Holtz EG. (2010)

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway

Blood 116(9):1574-1584. doi: 10.1182/blood-2009-11-253815
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Galy B, Ferring-Appel D, Sauer SW, Kaden S, Lyoumi S, Puy H, Kölker S, Gröne HJ, Hentze MW. (2010)

Iron regulatory proteins secure mitochondrial iron sufficiency and function

Cell Metab. 12(2):194-201. doi: 10.1016/j.cmet.2010.06.007
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Hentze MW, Preiss T. (2010)

The REM phase of gene regulation

Trends Biochem. Sci. 35(8):423-426. doi: 10.1016/j.tibs.2010.05.009
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Campillos M, Cases I, Hentze MW, Sanchez M. (2010)

SIREs: searching for iron-responsive elements

Nucleic Acids Res. 38(Web Server issue):W360-7. doi: 10.1093/nar/gkq371
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Hentze MW, Muckenthaler MU, Galy B, Camaschella C. (2010)

Two to tango: regulation of Mammalian iron metabolism

Cell 142(1):24-38. doi: 10.1016/j.cell.2010.06.028
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Mleczko-Sanecka K, Casanovas G, Ragab A, Breitkopf K, Müller A, Boutros M, Dooley S, Hentze MW, Muckenthaler MU. (2010)

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

Blood 115(13):2657-2665. doi: 10.1182/blood-2009-09-238105
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Lopes TJ, Luganskaja T, Vujić Spasić M, Hentze MW, Muckenthaler MU, Schümann K, Reich JG. (2010)

Systems analysis of iron metabolism: the network of iron pools and fluxes

BMC Syst Biol 4:112. doi: 10.1186/1752-0509-4-112
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Pisarev AV, Skabkin MA, Pisareva VP, Skabkina OV, Rakotondrafara AM, Hentze MW, Hellen CU, Pestova TV. (2010)

The role of ABCE1 in eukaryotic posttermination ribosomal recycling

Mol. Cell 37(2):196-210. doi: 10.1016/j.molcel.2009.12.034
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Vainshtein Y, Sanchez M, Brazma A, Hentze MW, Dandekar T, Muckenthaler MU. (2010)

The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays

BMC Bioinformatics 11:112. doi: 10.1186/1471-2105-11-112
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Duncan KE, Strein C, Hentze MW. (2009)

The SXL-UNR corepressor complex uses a PABP-mediated mechanism to inhibit ribosome recruitment to msl-2 mRNA

Mol. Cell 36(4):571-582. doi: 10.1016/j.molcel.2009.09.042
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Viatte L, Gröne HJ, Hentze MW, Galy B. (2009)

In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation

J. Mol. Med. 87(9):913-921. doi: 10.1007/s00109-009-0494-8
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Zdanowicz A, Thermann R, Kowalska J, Jemielity J, Duncan K, Preiss T, Darzynkiewicz E, Hentze MW. (2009)

Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression

Mol. Cell 35(6):881-888. doi: 10.1016/j.molcel.2009.09.009
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Clerici M, Mourão A, Gutsche I, Gehring NH, Hentze MW, Kulozik A, Kadlec J, Sattler M, Cusack S. (2009)

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

EMBO J. 28(15):2293-2306. doi: 10.1038/emboj.2009.175
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Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU. (2009)

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD

J. Mol. Med. 87(5):471-480. doi: 10.1007/s00109-009-0447-2
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Gehring NH, Lamprinaki S, Hentze MW, Kulozik AE. (2009)

The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay

PLoS Biol. 7(5):e1000120. doi: 10.1371/journal.pbio.1000120
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Gehring NH, Lamprinaki S, Kulozik AE, Hentze MW. (2009)

Disassembly of exon junction complexes by PYM

Cell 137(3):536-548. doi: 10.1016/j.cell.2009.02.042
Europe PMC | doi

Hentze MW. (2009)

EMBO Molecular Medicine: Conquering new frontiers

EMBO Mol Med 1(1):5. doi: 10.1002/emmm.200900011
Europe PMC | doi

Beilharz TH, Humphreys DT, Clancy JL, Thermann R, Martin DI, Hentze MW, Preiss T. (2009)

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells

PLoS ONE 4(8) doi: 10.1371/journal.pone.0006783
Europe PMC | doi

Ferring-Appel D, Hentze MW, Galy B. (2009)

Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism

Blood 113(3):679-687. doi: 10.1182/blood-2008-05-155093
Europe PMC | doi

Thoma C, Fraterman S, Gentzel M, Wilm M, Hentze MW. (2008)

Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail

RNA 14(8):1579-1589. doi: 10.1261/rna.1043908
Europe PMC | doi

Verga Falzacappa MV, Casanovas G, Hentze MW, Muckenthaler MU. (2008)

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

J. Mol. Med. 86(5):531-540. doi: 10.1007/s00109-008-0313-7
Europe PMC | doi

Ivanov PV, Gehring NH, Kunz JB, Hentze MW, Kulozik AE. (2008)

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

EMBO J. 27(5):736-747. doi: 10.1038/emboj.2008.17
Europe PMC | doi

Danckwardt S, Hentze MW, Kulozik AE. (2008)

3' end mRNA processing: molecular mechanisms and implications for health and disease

EMBO J. 27(3):482-498. doi: 10.1038/sj.emboj.7601932
Europe PMC | doi

Vujić Spasić M, Kiss J, Herrmann T, Galy B, Martinache S, Stolte J, Gröne HJ, Stremmel W, Hentze MW, Muckenthaler MU. (2008)

Hfe acts in hepatocytes to prevent hemochromatosis

Cell Metab. 7(2):173-178. doi: 10.1016/j.cmet.2007.11.014
Europe PMC | doi

Castoldi M, Schmidt S, Benes V, Hentze MW, Muckenthaler MU. (2008)

miChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probes

Nat Protoc 3(2):321-329. doi: 10.1038/nprot.2008.4
Europe PMC | doi

Galy B, Ferring-Appel D, Kaden S, Gröne HJ, Hentze MW. (2008)

Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum

Cell Metab. 7(1):79-85. doi: 10.1016/j.cmet.2007.10.006
Europe PMC | doi

Gehring NH, Hentze MW, Kulozik AE. (2008)

Tethering assays to investigate nonsense-mediated mRNA decay activating proteins

Meth. Enzymol. 448:467-482. doi: 10.1016/s0076-6879(08)02623-2
Europe PMC | doi

Muckenthaler MU, Galy B, Hentze MW. (2008)

Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network

Annu. Rev. Nutr. 28:197-213. doi: 10.1146/annurev.nutr.28.061807.155521
Europe PMC | doi

Pantopoulos K, Hentze MW. (2008)

Regulation of iron metabolism in higher eukaryotes: iron-sulfur centers as genetic switches

In: Ferreira GC, Moura JJG, Franco R (eds.), Inorganic biochemistry and regulatory mechanisms of iron metabolism. Wiley-VCH Verlag GmbH. pp 131-152.doi: 10.1002/9783527613700.ch08
Europe PMC | doi

Castoldi M, Benes V, Hentze MW, Muckenthaler MU. (2007)

miChip: a microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes

Methods 43(2):146-152. doi: 10.1016/j.ymeth.2007.04.009
Europe PMC | doi

Percy MJ, Sanchez M, Swierczek S, McMullin MF, Mojica-Henshaw MP, Muckenthaler MU, Prchal JT, Hentze MW. (2007)

Is congenital secondary erythrocytosis/polycythemia caused by activating mutations within the HIF-2 alpha iron-responsive element?

Blood 110(7):2776-2777. doi: 10.1182/blood-2007-03-082503
Europe PMC | doi

Till S, Lejeune E, Thermann R, Bortfeld M, Hothorn M, Enderle D, Heinrich C, Hentze MW, Ladurner AG. (2007)

A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain

Nat. Struct. Mol. Biol. 14(10):897-903. doi: 10.1038/nsmb1302
Europe PMC | doi