Location:EMBL-EBI Hinxton near Cambridge, UK
Staff Category:Staff Member
Contract Duration:1 year or until 31/10/2018, whichever is earliest
Grading:5 (monthly salary starting at £2,552 after tax). For more information about pay and benefits click here
Closing Date:21 September 2017
Reference Number:EBI_01043

Job Description

The Genomics Technology Infrastructure (GTI) team seeks a talented backend developer to work on capture Hi-C analysis at the European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI), which is located on the Wellcome Genome Campus near Cambridge in the UK.

As part of our collaborations we are working on a project to develop a Multi Scale Complex Genomics (MuG) virtual research environment (VRE). Our aim is to provide programmatic interfaces to best-in-class genomic annotation algorithms alongside 3D spatial representations of chromosomal confirmation. Key to this is ensuring the MuG VRE provides a broad range of analysis methods in line with researcher requirements. You will work alongside the existing core developers with responsibilities including:

  • Redeveloping existing algorithms to process and normalize Capture Hi-C data
  • Integrating these algorithms into the MuG VRE
  • Benchmarking of developed solutions against existing data sets
  • Communicating and collaborating with partners within the MuG consortium
  • Providing support and training to external partners

At EMBL-EBI, we help scientists realise the potential of ‘big data’ in biology by enabling them to exploit complex information to make discoveries that benefit mankind. Working for EMBL-EBI gives you an opportunity to apply your skills and energy for the greater good. As part of the European Molecular Biology Laboratory (EMBL), we are a non-profit, intergovernmental organisation funded by 23 member states and two associate member states and proud to be an equal-opportunity employer. We are located on the Wellcome Genome Campus near Cambridge in the UK, and our 600 staff are engineers, technicians, scientists and other professionals from all over the world.

Qualifications and Experience

You should hold an MSc in a computer or biological science or have equivalent experience.

You will bring to the role experience of Capture Hi-C and analysis methods associated with the protocol and a working knowledge of the algorithms employed e.g. CHiCAGO.

Maintaining communication with several collaborating teams is an important aspect of the role. Good communication and interpersonal skills are therefore essential. A flexible mindset, a capacity for independent work, and a commitment to the delivery of a high-quality public service, are all required.

Applicants must be experienced in Python and R. Knowledge of high throughput compute environments (LSF, SGE, COMPSs, Slurm) would be advantageous. Experience with Unix and software development tools including Git and GitHub are desired.


EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation.

We have an informal culture, international working environment and excellent professional development opportunities but one of the really amazing things about us is the concentration of technical and scientific expertise – something you probably won’t find anywhere else.

If you’ve ever visited the campus you’ll have experienced first-hand our friendly, collegial and supportive atmosphere, set in the beautiful Cambridgeshire countryside. Our staff also enjoy excellent sports facilities including a gym, a free shuttle bus, an on-site nursery, cafés and restaurant and a library.

Application Instructions

To apply please submit a covering letter and CV, with two referees, through our online system.

Additional Information

Applications are welcome from all nationalities - visa information will be discussed in more depth with applicants selected for interview.

EMBL-EBI is committed to achieving gender balance and strongly encourages applications from women, who are currently under-represented at all levels. Appointment will be based on merit alone.

This position is limited to the contract project duration specified.

Applications will close at 23:00 GMT on the date listed above.