Scientific Expert for Eukaryotic Protein Production
Location: Grenoble, France
Staff Category: Staff Member
Contract Duration: 3 years
Grading: 6 or 7; depending on qualification and experience
Closing Date: 15 January 2020
Reference Number: GR00141
EMBL Grenoble runs a protein expression facility that uses insect and mammalian cells as host organisms. The facilities have high internal usage by EMBL scientists for production of proteins and complexes for structural studies but are also open to other local researchers in the context of the Grenoble Partnership for Structural Biology (https://www.psb-grenoble.eu). The facilities are also used to perform a wide range of functional cell-based assays relevant to the projects of local scientists.  

Your role

The successful candidate will train new users, provide technical assistance and troubleshoot challenging protein expression and purification experiments. In addition, the post holder will be involved in developing new protocols for protein expression and may be involved in specific in-house research projects. In the future, the facility may also open more broadly to external users.

Besides overseeing day to day operation, maintaining supplies, servicing as well as upgrading the equipment of the facility, the candidate will committedly keep abreast of evolving protein expression methods and facilitate their implementation at the Outstation, including by closely interacting with the EMBL Protein Expression and Purification Facility in Heidelberg and with European protein production and purification networks. Occasional travel to other EMBL sites or to international meetings will constitute part of the duties as well as reporting and outreach activities.  

You have

Applicants should have a Technical, Master or PhD degree in biochemistry or a related field. Skills in eukaryotic cell culture, molecular biology, protein expression and purification are required and, in particular, demonstrable experience in insect cell expression using baculovirus. Excellent interpersonal and communications skills, as well as reactivity are essential in order to provide a high-quality service to users. Additionally, the ability to interact with a varied multicultural scientific community is required.  

You might also have

Working-knowledge of French would be an advantage but is not required. Demonstrated ability to lead negotiations for the purchase of instrumentation and reagents would be an asset.  

Why join us

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization with a very collaborative and family friendly atmosphere.   

What else you need to know

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1700 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new technologies and instruments in the life sciences, actively engage in technology transfer activities, and to integrate European life science research.

We strongly encourage interest from female applicants with the relevant qualifications. The working language of the institute is English.

Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

Further information about this position can be obtained from the Head of EMBL Grenoble, Stephen Cusack (cusack@embl.fr). See also http://www.embl.fr.