Cryo-Electron Microscopy Specialist – EMBL Imaging Centre
Location: Heidelberg, Germany
Staff Category: Staff Member
Contract Duration: 3 years
Grading: Commensurate, depending on qualifications and experience
Closing Date: 29 June 2020
Reference Number: HD01746
We are looking for a cryo-electron microscopy specialist to join the Electron Microscopy (EM) Team led by Simone Mattei at the new EMBL Imaging Centre (EMBL IC).

EMBL is currently constructing the EMBL IC to make the latest imaging technologies available to a broad, international user community of researchers from academia to industry. The Electron Microscopy Team will work in close collaboration with the Advanced Light Microscopy Team to offer a broad spectrum of electron and light microscopy technologies with special emphasis on correlative microscopy, covering all scales from structure determination of single protein complexes to imaging whole organisms. Dedicated service staff will provide bespoke user project support from sample preparation to image analysis.

The successful applicant will be part of a team comprising microscopy engineers, application specialists and image analysists having the mission of highest-level user service provision and technology development in cryo-EM. Before the opening of the EMBL IC the successful candidate will collaborate with the existing EMBL cryo-EM platform, the EM facility and EMBL research groups to work on selected pilot projects.

Other positions currently open in the EMBL IC:

Your role

The successful applicant will be responsible for:
  • Collecting, evaluating and processing data for single-particle analysis projects.
  • Ensuring smooth running of the instrumentation, interacting with service engineers and helping to maintain and develop the local infrastructure.
  • Introducing and training new users to cryo-EM technologies and auxiliary equipment, including assistance and trouble-shooting in sample preparation.
  • Staying up to date with the latest developments in the cryo-EM methodologies and developing novel workflows tailored to the EMBL IC.
  • Helping with the organisation and teaching of electron microscopy courses for the EMBL IC user community.

You have

  • PhD or equivalent experience in the life sciences, physics, engineering or related disciplines.
  • Relevant experience in operating cryogenic transmission electron microscopes.
  • Relevant experience in cryo-EM sample preparation and image processing.
  • Strong motivation to support and train users.
  • Excellent communication and organisation skills.
  • Fluency in English.

You might also have

  • Prior knowledge in cryo-electron tomography.
  • Prior knowledge in biochemistry and sample purification for structural biology studies.

Why join us

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits. Excellent child care facility is available on campus.

What else you need to know

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1600 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome. Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research. The working language of the institute is English. In your online application, you will be asked to include a cover letter, CV and the contact details of 3 referees. Further information about the position can be obtained from Stephanie Alexander, (, project manager of the EMBL IC. Interviews are planned for 20th/ 21st July 2020. The initial contract is for a period of three years with the possibility of a fixed-term extension.