Postdoctoral Fellow - Synthetic Biology Design and Evolution
Location: Heidelberg, Germany
Staff Category: Postdoctoral Fellow
Contract Duration: 2 years
Grading: NA
Closing Date: 15 March 2021
Reference Number: HD01929
The Steinmetz group is looking for an ambitious computational postdoctoral fellow who will combine innovative approaches in synthetic biology, laboratory evolution and genomics to measure the functional and molecular consequences of abrupt changes in genome organization. The evolutionary synthetic biology team in the Steinmetz lab uses the world’s first fully-synthetic eukaryote, Saccharomyces cerevisiae 2.0, and an on-demand genome-wide recombination system engineered into its genome (SCRaMbLE) to discover principles of genome design within an evolutionary context. The postdoctoral fellow will be responsible for processing and analyzing data generated from high-throughput genomics and experimental evolution experiments. S/he will join a highly collaborative, diverse and international team. A successful candidate will be highly motivated, creative and well-positioned to lead a scientific projects at all stages, from experimental design to manuscript preparation. In addition, this person will be both independent and enthusiastic to work collaboratively within a team. Together with a senior experimental postdoctoral fellow, s/he will lead all aspects of a multidisciplinary project that will require a broad background and desire to quickly learn new skills.  

Your role

  • Process, analyse and store data and results from high-throughput experiments
  • Design and implement large-scale experiments together with an experimental postdoc
  • Communicate scientific results via papers and other presentations
  • Collaborate with academic and industrial partners to develop new techniques and technologies
  • Present ongoing work and findings to colleagues internally and at conferences

You have

  • PhD in Molecular Biology, Genetics, Synthetic Biology or related field
  • Proficiency in a scripting language, e.g. R or Python
  • Experience with workflow management systems (e.g. Snakemake) and cluster computing environments (e.g. SLURM) are highly desired
  • Basic statistical knowledge
  • High-level English communication skills

You might also have

  • Experience with workflow management systems (e.g. Snakemake) and cluster computing environments (e.g. SLURM) are highly desired
  • Previous experience analyzing data from 3rd generation sequencing technologies, experimental evolution, and/or high-throughput phenotyping are highly desired

Why join us

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises from a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including your family and the availability of an excellent child care facility on campus.

What else you need to know

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1800 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome. Our other missions are to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research. The working language of the institute is English.