Postdoctoral Fellow: Synthetic Biology Design and Evolution
Location:Heidelberg, Germany
Staff Category:Postdoctoral Fellow
Contract Duration:2 years
Closing Date:12 August 2018
Reference Number:HD_01345

Job Description

The Steinmetz group is looking for an ambitious experimental postdoctoral fellow who will combine innovative approaches in synthetic biology, laboratory evolution and genomics to measure the functional and molecular consequences of abrupt changes in genome organization. The evolutionary synthetic biology team in the Steinmetz lab uses the world’s first fully-synthetic eukaryote, Saccharomyces cerevisiae 2.0, and an on-demand genome-wide recombination system engineered into its genome (SCRaMbLE) to discover principles of genome design within an evolutionary context. The postdoctoral fellow will be responsible for building an experimental research program that applies techniques from genomics, experimental evolution, chromosome-scale DNA synthesis and yeast molecular biology to measure the effects of structural variation on gene regulatory networks, speciation and more. S/he will join a highly collaborative, diverse and international team that includes collaborators in the laboratory of Dr. Patrick Cai at the University of Manchester as well as the Sc2.0 consortium led by Dr. Jef Boeke from NYU School of Medicine (

A successful candidate will be highly motivated, creative and well-positioned to lead a scientific projects at all stages, from experimental design to manuscript preparation. In addition, this person will be both independent and enthusiastic to work collaboratively within a team. Together with a senior computational postdoctoral fellow, s/he will lead all aspects of a multidisciplinary project that will require a broad background and desire to quickly learn new skills.

Qualifications and Experience

Candidates should have a Ph.D in a relevant field with experience in molecular biology, microbiology, genomics and/or synthetic biology. Successful applicants will have a strong track record leading independent research projects. Previous experience with 3rd generation sequencing technologies, experimental evolution, and/or high-throughput phenotyping are highly desired. In addition, a basic understanding of statistics and bioinformatics will be beneficial. The appointed candidate will be capable of working independently, but also enjoy being part of an interdisciplinary team of young scientists within a highly collaborative and international atmosphere. Flexibility, excellent communication skills and fluency in written and verbal English are essential.

Application Instructions

Please apply online through

Additional Information

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises from a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including your family.

Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.