The Genome

What happened when I had my genome sequenced

Biology 2.0’ – The Economist on 10 years of human genome

Initial impact of the sequencing of the human genome. Eric S. Lander. Nature 470, 187-197 (10 February 2011)

A Decade with the Human Genome Sequence: Charting a Course for Genomic Medicine’ - A day-long symposium organised by the National Human Genome Research Institute to commemorate the 10th anniversary of the human genome - the link includes speaker videos and their slides)

The Language of Life  Francis S. Collins

Functional Genomics

An integrated encyclopedia of DNA elements in the human genome
http://www.nature.com/nature/journal/v489/n7414/full/nature11247.html

Nature website
http://www.nature.com/encode/#/threads

Proteomics

Decoding signalling networks by mass spectrometry-based proteomics
http://www.nature.com/nrm/journal/v11/n6/abs/nrm2900.html

Cancer

The life history of 21 breast cancers.
http://www.cell.com/retrieve/pii/S0092867412005272

Mutational Processes Molding the Genomes of 21 Breast Cancers
http://www.cell.com/retrieve/pii/S0092867412005284

Precision Oncology: An Overview Garraway LA et al. Journal of Clinical Oncology 31, 1803-1805 (20 May 2013)

Single Cell Transcriptomics

A review on the potential of single-cell analyses
http://www.nature.com/nrg/journal/v14/n9/full/nrg3542.html

Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells.
http://www.nature.com/nature/journal/v498/n7453/full/nature12172.html

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing
http://www.nature.com/nature/journal/v500/n7464/full/nature12364.html

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells  
http://www.nature.com/nsmb/journal/v20/n9/full/nsmb.2660.html

Accounting for technical noise in single-cell RNA-seq experiments
http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.2645.html

Forensic Bioinformatics

Misconduct in science: An array of errors
http://www.economist.com/node/21528593

How Bright Promise in Cancer Testing Fell Apart
http://www.nytimes.com/2011/07/08/health/research/08genes.html?_r=0