Chemogenomic characterization of allosteric modulators.

Chemogenomic characterization of allosteric modulators.

A known inhibitor in green, aligned with two hits from the ViCi software, in the binding pocket of beta lactamase. Important interactions maintained are highlighted with red circles and those created for exploration with full red spots.

A known inhibitor in green, aligned with two hits from the ViCi software, in the binding pocket of beta lactamase. Important interactions maintained are highlighted with red circles and those created for exploration with full red spots.

Chemistry has never been more important for biological research than today. The continual development of new reagents, probes and inhibitor technologies are enabling increasingly precise and fine grained understanding of macromolecular function in the cell.

The EMBL Centre for Chemical Biology promotes and supports researchers using chemical approaches across all the EMBL sites. The Centre organises a regular Chemical Biology retreat bringing together EMBL researchers seeking to create even better molecular tools for helping to understand biology. It also organises biennially one of the largest Chemical Biology conferences worldwide.