Seminar Colour Guide:              
Hamburg Speaker
Friday, 23 August 2019, 13:00Add to calendarStructure and Function of the ESX-3/Type VII secretion systemSebastian Geibel, University of Würzburg, Institute for Molecular Infection Biology, , GermanyHost: Matthias WilmannsSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Wednesday, 28 August 2019, 13:00Add to calendarSAXS at the Life Sciences X-ray scattering beamline (LiX)James Byrnes, Brookhaven National Laboratory, NSLS-II, Upton, NY 11973-5000, USAHost: Dmitri SvergunSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 6 September 2019, 13:00Add to calendarATSAS 3.0 SOFTWARE SUITE FOR SMALL ANGLE SCATTERING FROM MACROMOLECULAR SOLUTIONSDaniel Franke, EMBL Hamburg Unit, GermanyHost: Dmitri SvergunSeminar Room 48e, EMBL Hamburg
Abstract: We present version 3.0 of ATSAS, a comprehensive software suite for the analysis of
small angle scattering of biological macromolecules in solution [1]. ATSAS is an
extensive cross-platform package with applications for all stages of the workflow,
from primary data processing to ab-initio and rigid body modelling. It includes
applications to integrate information from X-ray crystallography, nuclear magnetic
resonance spectroscopy, electron microscopy and atomistic homology modelling to
construct hybrid models based on the scattering data. In this major release we (a)
included initial support for the PDBx/mmCIF [2] file format of the PDB for all
applications that work with atomic structures; (b) accounted for the recommendations
given by the publication guidelines of SAS data [3]; (c) moved GUI applications to
the modern Qt5 GUI toolkit and (d) provided an improved platform support and modern
installer wizards for all of them. In addition, multiple new applications are included:
DAMMIX, a tool to restore the shape of unknown component in evolving systems ab initio,
e.g. during fibril formation [4]; FLEXBIN, a program for flexible docking of binary
complexes; DATMW, a unified tool to assess the molecular weight (MW) of a macromolecule
in solution, which includes support for the established methods as well as for a new
Bayesian approach reporting a consensus MW estimate together with a credibility
interval [5]; IMGSIM, a simulation program to generate 2D scattering images from
atomic models; and DATMIF, an application to directly ab-initio model experimental
data without need of a distance distribution function. ATSAS 3.0 is available for
multiple platforms, including, but not limited to: Windows 10, Ubuntu 18.04,
Debian 9 and MacOS 10.14. The ATSAS packages are freely available for academic users
from the URL https://www.emblhamburg.de/biosaxs/software.html. Additionally, an
ATSAS-online interface to submit jobs to the EMBL-Hamburg computational cluster for
major ATSAS programs is available at https://www.embl-hamburg.de/biosaxs/atsas-online/.

Acknowledgements
The research was funded by Horizon 2020 programme of the European Union, grant iNEXT
project number 653706, and Bundesministerium für Bildung und Forschung, grant TT-SAS
number 05K2016.
Hamburg Speaker
Friday, 27 September 2019, 13:00Add to calendarTo be announcedStefan Fiedler, EMBL Hamburg Unit, GermanyHost: Stefan FiedlerSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 11 October 2019, 13:00Add to calendarTo be announcedCy Jeffries, EMBL Hamburg Unit, GermanyHost: Dmitri SvergunSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 18 October 2019, 13:00Add to calendarHigh-throughput X-ray imaging and tomography for bio-applications at the EMBLMaxime Polikarpov, EMBL Hamburg Unit, GermanyHost: Thomas R. SchneiderSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 25 October 2019, 13:00Add to calendarHow the Advanced Light and Fluorescence Microscopy (ALFM) facility at CSSB can support your researchRoland Thuenauer, CSSB, Hamburg, GermanyHost: Jan KosinskiSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 15 November 2019, 13:00Add to calendarTo be announcedDavid von Stetten, EMBL Hamburg Unit, GermanyHost: Thomas R. SchneiderSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 22 November 2019, 13:00Add to calendarTo be announcedSebastian Glatt, Max Planck Research Group Leader, , Malopolska Centre of Biotechnology (MCB), Jagiellonian University Krakow, PolandHost: Jan KosinskiSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 29 November 2019, 13:00Add to calendarTo be announcedSamuel Pazicky, EMBL Hamburg Unit, GermanyHost: Christian LoewSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 6 December 2019, 13:00Add to calendarTo be announcedKim Bartels, EMBL Hamburg Unit, GermanyHost: Christian LoewSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 13 December 2019, 13:00Add to calendarTo be announcedThomas Crosskey, EMBL Hamburg Unit, GermanyHost: Matthias WilmannsSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 17 January 2020, 13:00Add to calendarTo be announcedIsabel Bento, EMBL Hamburg Unit, GermanyHost: Thomas R. SchneiderSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 24 January 2020, 13:00Add to calendarTo be announcedSusanne Witt, CSSB, Hamburg, GermanyHost: Jan KosinskiSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 7 February 2020, 13:00Add to calendarTo be announcedMeytal Landau, Department of Biology, Technion Israel Institute of Technology and, EMBL Hamburg, IsraelHost: Matthias WilmannsSeminar Room 48e, EMBL Hamburg
Hamburg Speaker
Friday, 20 March 2020, 13:00Add to calendarExploration of the complete peroxisomal proteomeMaya Schuldiner, Department of Molecular Genetics, Weizmann Institute of Science, IsraelHost: Matthias WilmannsSeminar Room 48e, EMBL Hamburg