EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Biography

  • PhD 1998, Freie Universität Berlin.
    Predoctoral and postdoctoral research at the National Institutes of Health (NIH), Bethesda.
    Group leader at EMBL since 1999.
    Head of Gene Expression Unit 2006-2010.
    Head of Cell Biology and Biophysics Unit since 2010.
    ERC Advanced Investigator since 2016.

Publications

Total: 155 publication(s)

2018

Pękowska A, Klaus B, Xiang W, Severino J, Daigle N, Klein FA, Oleś M, Casellas R, Ellenberg J, Steinmetz LM, Bertone P, Huber W. (2018)

Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency.

Cell Syst doi: 10.1016/j.cels.2018.09.003
Europe PMC | doi

Ellenberg J, Swedlow JR, Barlow M, Cook CE, Sarkans U, Patwardhan A, Brazma A, Birney E. (2018)

A call for public archives for biological image data.

Nat. Methods 15(11):849-854. doi: 10.1038/s41592-018-0195-8
Europe PMC | doi

Popovic D, Koch B, Kueblbeck M, Ellenberg J, Pelkmans L. (2018)

Multivariate Control of Transcript to Protein Variability in Single Mammalian Cells.

Cell Syst doi: 10.1016/j.cels.2018.09.001
Europe PMC | doi

Cai Y, Hossain MJ, Hériché JK, Politi AZ, Walther N, Koch B, Wachsmuth M, Nijmeijer B, Kueblbeck M, Martinic-Kavur M, Ladurner R, Alexander S, Peters JM, Ellenberg J. (2018)

Experimental and computational framework for a dynamic protein atlas of human cell division.

Nature doi: 10.1038/s41586-018-0518-z
Europe PMC | doi

Strauss S, Nickels PC, Strauss MT, Jimenez Sabinina V, Ellenberg J, Carter JD, Gupta S, Janjic N, Jungmann R. (2018)

Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging.

Nat Methods doi: 10.1038/s41592-018-0105-0
Europe PMC | doi

Reichmann J, Nijmeijer B, Hossain MJ, Eguren M, Schneider I, Politi AZ, Roberti MJ, Hufnagel L, Hiiragi T, Ellenberg J. (2018)

Dual-spindle formation in zygotes keeps parental genomes apart in early mammalian embryos.

Science 361(6398):189-193. doi: 10.1126/science.aar7462
Europe PMC | doi

Koch B, Nijmeijer B, Kueblbeck M, Cai Y, Walther N, Ellenberg J. (2018)

Generation and validation of homozygous fluorescent knock-in cells using CRISPR-Cas9 genome editing.

Nat Protoc 13(6):1465-1487. doi: 10.1038/nprot.2018.042
Europe PMC | doi

Politi AZ, Cai Y, Walther N, Hossain MJ, Koch B, Wachsmuth M, Ellenberg J. (2018)

Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four-dimensional imaging.

Nat Protoc 13(6):1445-1464. doi: 10.1038/nprot.2018.040
Europe PMC | doi

Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Hériché JK, Wutz G, van der Lelij P, Kreidl E, Hutchins JR, Axelsson-Ekker H, Ellenberg J, Hyman AA, Peters JM, Mechtler K. (2018)

The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.

EMBO J. 37(15) doi: 10.15252/embj.201797150
Europe PMC | doi

Reichmann J, Eguren M, Lin Y, Schneider I, Ellenberg J. (2018)

Live imaging of cell division in preimplantation mouse embryos using inverted light-sheet microscopy.

Methods Cell Biol. 145:279-292. doi: 10.1016/bs.mcb.2018.03.030
Europe PMC | doi

Walther N, Ellenberg J. (2018)

Quantitative live and super-resolution microscopy of mitotic chromosomes

Methods Cell Biol. doi: 10.1016/bs.mcb.2018.03.014
Europe PMC | doi

Li Y, Mund M, Hoess P, Deschamps J, Matti U, Nijmeijer B, Sabinina VJ, Ellenberg J, Schoen I, Ries J. (2018)

Real-time 3D single-molecule localization using experimental point spread functions.

Nat Methods 15(5) doi: 10.1038/nmeth.4661
Europe PMC | doi

Xiang W, Roberti MJ, Hériché JK, Huet S, Alexander S, Ellenberg J. (2018)

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.

J Cell Biol doi: 10.1083/jcb.201709074
Europe PMC | doi

Barton C, Morganella S, Ødegård-Fougner Ø, Alexander S, Ries J, Fitzgerald T, Ellenberg J, Birney E. (2018)

ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy.

PLoS Comput Biol 14(3) doi: 10.1371/journal.pcbi.1006002
Europe PMC | doi

Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T. (2018)

Author Correction: Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.

Nat. Cell Biol. 20(4) doi: 10.1038/s41556-018-0044-0
Europe PMC | doi

Otsuka S, Ellenberg J. (2018)

Mechanisms of nuclear pore complex assembly: Two different ways of building one molecular machine

FEBS letters 592(4) doi: 10.1002/1873-3468.12905
Europe PMC | doi

Otsuka S, Steyer AM, Schorb M, Hériché JK, Hossain MJ, Sethi S, Kueblbeck M, Schwab Y, Beck M, Ellenberg J. (2018)

Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings

Nat. Struct. Mol. Biol. 25(1):21-28. doi: 10.1038/s41594-017-0001-9
Europe PMC | doi


2017

Wutz G, Várnai C, Nagasaka K, Cisneros DA, Stocsits RR, Tang W, Schoenfelder S, Jessberger G, Muhar M, Hossain MJ, Walther N, Koch B, Kueblbeck M, Ellenberg J, Zuber J, Fraser P, Peters JM. (2017)

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.

EMBO J. 36(24) doi: 10.15252/embj.201798004
Europe PMC | doi

Germier T, Kocanova S, Walther N, Bancaud A, Shaban HA, Sellou H, Politi AZ, Ellenberg J, Gallardo F, Bystricky K. (2017)

Real-Time Imaging of a Single Gene Reveals Transcription-Initiated Local Confinement.

Biophys. J. 113(7):1383-1394. doi: 10.1016/j.bpj.2017.08.014
Europe PMC | doi


2016

S Pedersen R, Karemore G, Gudjonsson T, Rask MB, Neumann B, Hériché JK, Pepperkok R, Ellenberg J, Gerlich DW, Lukas J, Lukas C. (2016)

Profiling DNA damage response following mitotic perturbations.

Nat Commun 7(13887):1-12. doi: 10.1038/ncomms13887
Europe PMC | doi

Otsuka S, Bui KH, Schorb M, Hossain MJ, Politi AZ, Koch B, Eltsov M, Beck M, Ellenberg J. (2016)

Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope

Elife 5 doi: 10.7554/eLife.19071
Europe PMC | doi

Uhlen M, Bandrowski A, Carr S, Edwards A, Ellenberg J, Lundberg E, Rimm DL, Rodriguez H, Hiltke T, Snyder M, Yamamoto T. (2016)

A proposal for validation of antibodies.

Nat. Methods 13(10) doi: 10.1038/nmeth.3995
Europe PMC | doi

Cuylen S, Blaukopf C, Politi AZ, Müller-Reichert T, Neumann B, Poser I, Ellenberg J, Hyman AA, Gerlich DW. (2016)

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.

Nature 535(7611):308-312. doi: 10.1038/nature18610
Europe PMC | doi

Saliba AE, Vonkova I, Deghou S, Ceschia S, Tischer C, Kugler KG, Bork P, Ellenberg J, Gavin AC. (2016)

A protocol for the systematic and quantitative measurement of protein-lipid interactions using the liposome-microarray-based assay.

Nat Protoc 11(6):1021-1038. doi: 10.1038/nprot.2016.059
Europe PMC | doi

Jupp S, Malone J, Burdett T, Heriche JK, Williams E, Ellenberg J, Parkinson H, Rustici G. (2016)

The cellular microscopy phenotype ontology.

J Biomed Semantics 7:28. doi: 10.1186/s13326-016-0074-0
Europe PMC | doi

Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T. (2016)

Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.

Nat. Cell Biol. 18(6):692-699. doi: 10.1038/ncb3353
Europe PMC | doi

Isokane M, Walter T, Mahen R, Nijmeijer B, Hériché JK, Miura K, Maffini S, Ivanov MP, Kitajima TS, Peters JM, Ellenberg J. (2016)

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.

J. Cell Biol. 212(6):647-659. doi: 10.1083/jcb.201408089
Europe PMC | doi

Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de Medeiros G, Norlin N, Hiiragi T, Hufnagel L, Ellenberg J. (2016)

Inverted light-sheet microscope for imaging mouse pre-implantation development.

Nat. Methods 13(2):139-142. doi: 10.1038/nmeth.3690
Europe PMC | doi


2015

Mardin BR, Drainas AP, Waszak SM, Weischenfeldt J, Isokane M, Stütz AM, Raeder B, Efthymiopoulos T, Buccitelli C, Segura-Wang M, Northcott P, Pfister SM, Lichter P, Ellenberg J, Korbel JO. (2015)

A cell-based model system links chromothripsis with hyperploidy.

Mol. Syst. Biol. 11(9):828. doi: 10.15252/msb.20156505
Europe PMC | doi

Vonkova I, Saliba AE, Deghou S, Anand K, Ceschia S, Doerks T, Galih A, Kugler KG, Maeda K, Rybin V, van Noort V, Ellenberg J, Bork P, Gavin AC. (2015)

Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains.

Cell Rep 12(9):1519-1530. doi: 10.1016/j.celrep.2015.07.054
Europe PMC | doi

Metchat A, Eguren M, Hossain JM, Politi AZ, Huet S, Ellenberg J. (2015)

An actin-dependent spindle position checkpoint ensures the asymmetric division in mouse oocytes (Retraction of vol 6, 7784, 2015)

Nat Commun 6 doi: 10.1038/ncomms9124
Europe PMC | doi

Boni A, Politi AZ, Strnad P, Xiang W, Hossain MJ, Ellenberg J. (2015)

Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells.

J. Cell Biol. 209(5):705-720. doi: 10.1083/jcb.201409133
Europe PMC | doi

Wachsmuth M, Conrad C, Bulkescher J, Koch B, Mahen R, Isokane M, Pepperkok R, Ellenberg J. (2015)

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.

Nat. Biotechnol. 33(4):384-389. doi: 10.1038/nbt.3146
Europe PMC | doi

Lees JG, Hériché JK, Morilla I, Fernández JM, Adler P, Krallinger M, Vilo J, Valencia A, Ellenberg J, Ranea JA, Orengo C. (2015)

FUN-L: Gene prioritization for RNAi screens.

Bioinformatics 31(12):2052-2053. doi: 10.1093/bioinformatics/btv073
Europe PMC | doi

Solc P, Kitajima TS, Yoshida S, Brzakova A, Kaido M, Baran V, Mayer A, Samalova P, Motlik J, Ellenberg J. (2015)

Multiple Requirements of PLK1 during Mouse Oocyte Maturation.

PLoS ONE 10(2) doi: 10.1371/journal.pone.0116783
Europe PMC | doi


2014

van der Lelij P, Stocsits RR, Ladurner R, Petzold G, Kreidl E, Koch B, Schmitz J, Neumann B, Ellenberg J, Peters JM. (2014)

SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs

EMBO J. 33(22):2643-2658. doi: 10.15252/embj.201488202
Europe PMC | doi

Mahen R, Koch B, Wachsmuth M, Politi AZ, Perez-Gonzalez A, Mergenthaler J, Cai Y, Ellenberg J. (2014)

Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells

Mol. Biol. Cell 25(22):3610-3618. doi: 10.1091/mbc.e14-06-1091
Europe PMC | doi

Rohn JL, Patel JV, Neumann B, Bulkescher J, Mchedlishvili N, McMullan RC, Quintero OA, Ellenberg J, Baum B. (2014)

Myo19 Ensures Symmetric Partitioning of Mitochondria and Coupling of Mitochondrial Segregation to Cell Division.

Curr. Biol. 24(21):2598-2605. doi: 10.1016/j.cub.2014.09.045
Europe PMC | doi

Tegha-Dunghu J, Bausch E, Neumann B, Wuensche A, Walter T, Ellenberg J, Gruss OJ. (2014)

MAP1S controls microtubule stability throughout the cell cycle in human cells.

J. Cell. Sci. 127(23):5007-5013. doi: 10.1242/jcs.136457
Europe PMC | doi

Hériché JK, Lees JG, Morilla I, Walter T, Petrova B, Roberti MJ, Hossain MJ, Adler P, Fernández JM, Krallinger M, Haering CH, Vilo J, Valencia A, Ranea JA, Orengo C, Ellenberg J. (2014)

Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation

Mol. Biol. Cell 25(16):2522-2536. doi: 10.1091/mbc.e13-04-0221
Europe PMC | doi

Keller D, Orpinell M, Olivier N, Wachsmuth M, Mahen R, Wyss R, Hachet V, Ellenberg J, Manley S, Gönczy P. (2014)

Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells

J. Cell Biol. 204(5):697-712. doi: 10.1083/jcb.201307049
Europe PMC | doi

Otsuka S, Szymborska A, Ellenberg J. (2014)

Imaging the assembly, structure, and function of the nuclear pore inside cells.

Methods Cell Biol. 122:219-238. doi: 10.1016/b978-0-12-417160-2.00010-2
Europe PMC | doi

Saliba AE, Vonkova I, Ceschia S, Findlay GM, Maeda K, Tischer C, Deghou S, van Noort V, Bork P, Pawson T, Ellenberg J, Gavin AC. (2014)

A quantitative liposome microarray to systematically characterize protein-lipid interactions

Nat. Methods 11(1):47-50. doi: 10.1038/nmeth.2734
Europe PMC | doi


2013

Walter A, Chapuis C, Huet S, Ellenberg J. (2013)

Crowded chromatin is not sufficient for heterochromatin formation and not required for its maintenance

J. Struct. Biol. 184(3):445-453. doi: 10.1016/j.jsb.2013.10.004
Europe PMC | doi

Tedeschi A, Wutz G, Huet S, Jaritz M, Wuensche A, Schirghuber E, Davidson IF, Tang W, Cisneros DA, Bhaskara V, Nishiyama T, Vaziri A, Wutz A, Ellenberg J, Peters JM. (2013)

Wapl is an essential regulator of chromatin structure and chromosome segregation

Nature 501(7468):564-568. doi: 10.1038/nature12471
Europe PMC | doi

Szymborska A, de Marco A, Daigle N, Cordes VC, Briggs JA, Ellenberg J. (2013)

Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging

Science 341(6146):655-658. doi: 10.1126/science.1240672
Europe PMC | doi

Mardin BR, Isokane M, Cosenza MR, Krämer A, Ellenberg J, Fry AM, Schiebel E. (2013)

EGF-induced centrosome separation promotes mitotic progression and cell survival

Dev. Cell 25(3):229-240. doi: 10.1016/j.devcel.2013.03.012
Europe PMC | doi

Pau G, Walter T, Neumann B, Hériché JK, Ellenberg J, Huber W. (2013)

Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay.

BMC Bioinformatics 14:308. doi: 10.1186/1471-2105-14-308
Europe PMC | doi


2012

Bancaud A, Lavelle C, Huet S, Ellenberg J. (2012)

A fractal model for nuclear organization: current evidence and biological implications

Nucleic Acids Res. 40(18):8783-8792. doi: 10.1093/nar/gks586
Europe PMC | doi

Mall M, Walter T, Gorjánácz M, Davidson IF, Nga Ly-Hartig TB, Ellenberg J, Mattaj IW. (2012)

Mitotic lamin disassembly is triggered by lipid-mediated signaling

J. Cell Biol. 198(6):981-990. doi: 10.1083/jcb.201205103
Europe PMC | doi

Courtois A, Schuh M, Ellenberg J, Hiiragi T. (2012)

The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development

J. Cell Biol. 198(3):357-370. doi: 10.1083/jcb.201202135
Europe PMC | doi

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R. (2012)

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway

Nat. Cell Biol. 14(7):764-774. doi: 10.1038/ncb2510
Europe PMC | doi

Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J. (2012)

Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.

Cell Death Differ. 19(5):798-807. doi: 10.1038/cdd.2011.150
Europe PMC | doi

Scolz M, Widlund PO, Piazza S, Bublik DR, Reber S, Peche LY, Ciani Y, Hubner N, Isokane M, Monte M, Ellenberg J, Hyman AA, Schneider C, Bird AW. (2012)

GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration

PLoS ONE 7(12):e51259. doi: 10.1371/journal.pone.0051259
Europe PMC | doi


2011

Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W. (2011)

Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases

Genome Res. 21(11):1955-1968. doi: 10.1101/gr.116087.110
Europe PMC | doi

Kitajima TS, Ohsugi M, Ellenberg J. (2011)

Complete kinetochore tracking reveals error-prone homologous chromosome biorientation in mammalian oocytes

Cell 146(4):568-581. doi: 10.1016/j.cell.2011.07.031
Europe PMC | doi

Ng K, Daigle N, Bancaud A, Ohhata T, Humphreys P, Walker R, Ellenberg J, Wutz A. (2011)

A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells

Mol. Biol. Cell 22(14):2634-2645. doi: 10.1091/mbc.e11-02-0146
Europe PMC | doi

Sironi L, Solon J, Conrad C, Mayer TU, Brunner D, Ellenberg J. (2011)

Automatic quantification of microtubule dynamics enables RNAi-screening of new mitotic spindle regulators

Cytoskeleton (Hoboken) 68(5):266-278. doi: 10.1002/cm.20510
Europe PMC | doi

Mori M, Monnier N, Daigle N, Bathe M, Ellenberg J, Lénárt P. (2011)

Intracellular transport by an anchored homogeneously contracting F-actin meshwork

Curr. Biol. 21(7):606-611. doi: 10.1016/j.cub.2011.03.002
Europe PMC | doi

Bolhy S, Bouhlel I, Dultz E, Nayak T, Zuccolo M, Gatti X, Vallee R, Ellenberg J, Doye V. (2011)

A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase

J. Cell Biol. 192(5):855-871. doi: 10.1083/jcb.201007118
Europe PMC | doi

Conrad C, Wünsche A, Tan TH, Bulkescher J, Sieckmann F, Verissimo F, Edelstein A, Walter T, Liebel U, Pepperkok R, Ellenberg J. (2011)

Micropilot: automation of fluorescence microscopy-based imaging for systems biology

Nat. Methods 8(3):246-249. doi: 10.1038/nmeth.1558
Europe PMC | doi

Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R. (2011)

The quantitative proteome of a human cell line

Mol. Syst. Biol. 7:549. doi: 10.1038/msb.2011.82
Europe PMC | doi

Mall M, Walter T, Gorjanacz M, Ellenberg J, Mattaj IW. (2011)

Mitotic Lamin disassembly is triggered by a lipid-mediated mitotic Lipin signaling pathway

MOL BIOL CELL 22


2010

Bancaud A, Huet S, Rabut G, Ellenberg J. (2010)

Fluorescence perturbation techniques to study mobility and molecular dynamics of proteins in live cells: FRAP, photoactivation, photoconversion, and FLIP

Cold Spring Harb Protoc 2010(12):pdb.top90. doi: 10.1101/pdb.top90
Europe PMC | doi

Landsverk HB, Mora-Bermúdez F, Landsverk OJ, Hasvold G, Naderi S, Bakke O, Ellenberg J, Collas P, Syljuåsen RG, Küntziger T. (2010)

The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response

EMBO Rep. 11(11):868-875. doi: 10.1038/embor.2010.134
Europe PMC | doi

Dultz E, Ellenberg J. (2010)

Live imaging of single nuclear pores reveals unique assembly kinetics and mechanism in interphase

J. Cell Biol. 191(1):15-22. doi: 10.1083/jcb.201007076
Europe PMC | doi

Held M, Schmitz MH, Fischer B, Walter T, Neumann B, Olma MH, Peter M, Ellenberg J, Gerlich DW. (2010)

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.

Nat. Methods 7(9):747-754. doi: 10.1038/nmeth.1486
Europe PMC | doi

Terjung S, Walter T, Seitz A, Neumann B, Pepperkok R, Ellenberg J. (2010)

High-throughput microscopy using live mammalian cells.

Cold Spring Harb Protoc 2010(7):pdb.top84. doi: 10.1101/pdb.top84
Europe PMC | doi

Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM. (2010)

Systematic analysis of human protein complexes identifies chromosome segregation proteins

Science 328(5978):593-599. doi: 10.1126/science.1181348
Europe PMC | doi

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J. (2010)

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

Nature 464(7289):721-727. doi: 10.1038/nature08869
Europe PMC | doi

Walter T, Held M, Neumann B, Hériché JK, Conrad C, Pepperkok R, Ellenberg J. (2010)

Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging

J. Struct. Biol. 170(1):1-9. doi: 10.1016/j.jsb.2009.10.004
Europe PMC | doi

Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S, Ragan MA, Schneider JE, Tomancak P, Hériché JK. (2010)

Visualization of image data from cells to organisms

Nat. Methods 7(3 Suppl):S26-41. doi: 10.1038/nmeth.1431
Europe PMC | doi

Huet S, Avilov SV, Ferbitz L, Daigle N, Cusack S, Ellenberg J. (2010)

Nuclear import and assembly of influenza A virus RNA polymerase studied in live cells by fluorescence cross-correlation spectroscopy

J. Virol. 84(3):1254-1264. doi: 10.1128/jvi.01533-09
Europe PMC | doi


2009

Bancaud A, Huet S, Daigle N, Mozziconacci J, Beaudouin J, Ellenberg J. (2009)

Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin

EMBO J. 28(24):3785-3798. doi: 10.1038/emboj.2009.340
Europe PMC | doi

Harder N, Mora-Bermúdez F, Godinez WJ, Wünsche A, Eils R, Ellenberg J, Rohr K. (2009)

Automatic analysis of dividing cells in live cell movies to detect mitotic delays and correlate phenotypes in time

Genome Res. 19(11):2113-2124. doi: 10.1101/gr.092494.109
Europe PMC | doi

Dultz E, Huet S, Ellenberg J. (2009)

Formation of the nuclear envelope permeability barrier studied by sequential photoswitching and flux analysis

Biophys. J. 97(7):1891-1897. doi: 10.1016/j.bpj.2009.07.024
Europe PMC | doi

Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, Ellenberg J, Panier S, Durocher D, Bartek J, Lukas J, Lukas C. (2009)

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

Cell 136(3):435-446. doi: 10.1016/j.cell.2008.12.041
Europe PMC | doi

Keppler A, Ellenberg J. (2009)

Chromophore-assisted laser inactivation of alpha- and gamma-tubulin SNAP-tag fusion proteins inside living cells

ACS Chem. Biol. 4(2):127-138. doi: 10.1021/cb800298u
Europe PMC | doi


2008

Lu W, Gotzmann J, Sironi L, Jaeger VM, Schneider M, Lüke Y, Uhlén M, Szigyarto CA, Brachner A, Ellenberg J, Foisner R, Noegel AA, Karakesisoglou I. (2008)

Sun1 forms immobile macromolecular assemblies at the nuclear envelope

Biochim. Biophys. Acta 1783(12):2415-2426. doi: 10.1016/j.bbamcr.2008.09.001
Europe PMC | doi

Schuh M, Ellenberg J. (2008)

A new model for asymmetric spindle positioning in mouse oocytes

Curr. Biol. 18(24):1986-1992. doi: 10.1016/j.cub.2008.11.022
Europe PMC | doi

Erfle H, Neumann B, Rogers P, Bulkescher J, Ellenberg J, Pepperkok R. (2008)

Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates

J Biomol Screen 13(7):575-580. doi: 10.1177/1087057108320133
Europe PMC | doi

Antonin W, Ellenberg J, Dultz E. (2008)

Nuclear pore complex assembly through the cell cycle: regulation and membrane organization

FEBS Lett. 582(14):2004-2016. doi: 10.1016/j.febslet.2008.02.067
Europe PMC | doi

Tegha-Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, Held M, Rogers P, Hupfeld K, Ruppert T, Ellenberg J, Gruss OJ. (2008)

EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.

J. Cell. Sci. 121(Pt 10):1718-1726. doi: 10.1242/jcs.019174
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Dultz E, Zanin E, Wurzenberger C, Braun M, Rabut G, Sironi L, Ellenberg J. (2008)

Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells

J. Cell Biol. 180(5):857-865. doi: 10.1083/jcb.200707026
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Walter T, Held M, Neumann B, Heriche JK, Conrad C, Pepperkok R, Ellenberg J. (2008)

A genome wide RNAI screen by time lapse microscopy in order to identify mitotic genes - Computational aspects and challenges.

Paper presented at the 2008 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Paris, France, 14-17 May 2008.I S Biomed Imaging 1:328-331. doi: 10.1109/ISBI.2008.4540999
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2007

Daigle N, Ellenberg J. (2007)

LambdaN-GFP: an RNA reporter system for live-cell imaging

Nat. Methods 4(8):633-636. doi: 10.1038/nmeth1065
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Schuh M, Ellenberg J. (2007)

Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes

Cell 130(3):484-498. doi: 10.1016/j.cell.2007.06.025
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Mora-Bermúdez F, Gerlich D, Ellenberg J. (2007)

Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase

Nat. Cell Biol. 9(7):822-831. doi: 10.1038/ncb1606
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Simpson JC, Cetin C, Erfle H, Joggerst B, Liebel U, Ellenberg J, Pepperkok R. (2007)

An RNAi screening platform to identify secretion machinery in mammalian cells

Paper presented at the International Workshop on Molecular Systems Biology, Bielefeld, GERMANY, JUN, 2006.J. Biotechnol. 129(2):352-365. doi: 10.1016/j.jbiotec.2006.12.027
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Dultz E, Ellenberg J. (2007)

Nuclear envelope

CURR BIOL 17(5):R154-R156. doi: 10.1016/j.cub.2006.12.035
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Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP, Hart DJ. (2007)

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit

Nat. Struct. Mol. Biol. 14(3):229-233. doi: 10.1038/nsmb1212
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Mora-Bermúdez F, Ellenberg J. (2007)

Measuring structural dynamics of chromosomes in living cells by fluorescence microscopy

Methods 41(2):158-167. doi: 10.1016/j.ymeth.2006.07.035
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Erfle H, Neumann B, Liebel U, Rogers P, Held M, Walter T, Ellenberg J, Pepperkok R. (2007)

Reverse transfection on cell arrays for high content screening microscopy.

Nat Protoc 2(2):392-399. doi: 10.1038/nprot.2006.483
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2006

Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prévôt B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R. (2006)

Minimizing the risk of reporting false positives in large-scale RNAi screens

Nat. Methods 3(10):777-779. doi: 10.1038/nmeth1006-777
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Pepperkok R, Ellenberg J. (2006)

High-throughput fluorescence microscopy for systems biology

Nat. Rev. Mol. Cell Biol. 7(9):690-696. doi: 10.1038/nrm1979
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Gerlich D, Koch B, Dupeux F, Peters JM, Ellenberg J. (2006)

Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication

Curr. Biol. 16(15):1571-1578. doi: 10.1016/j.cub.2006.06.068
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Keppler A, Arrivoli C, Sironi L, Ellenberg J. (2006)

Fluorophores for live cell imaging of AGT fusion proteins across the visible spectrum

BioTechniques 41(2):167-70, 172, 174-5. doi: 10.2144/000112216
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Kudo NR, Wassmann K, Anger M, Schuh M, Wirth KG, Xu H, Helmhart W, Kudo H, McKay M, Maro B, Ellenberg J, de Boer P, Nasmyth K. (2006)

Resolution of chiasmata in oocytes requires separase-mediated proteolysis

Cell 126(1):135-146. doi: 10.1016/j.cell.2006.05.033
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Ribbeck K, Groen AC, Santarella R, Bohnsack MT, Raemaekers T, Köcher T, Gentzel M, Görlich D, Wilm M, Carmeliet G, Mitchison TJ, Ellenberg J, Hoenger A, Mattaj IW. (2006)

NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules

Mol. Biol. Cell 17(6):2646-2660. doi: 10.1091/mbc.e05-12-1178
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Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J. (2006)

High-throughput RNAi screening by time-lapse imaging of live human cells.

Nat. Methods 3(5):385-390. doi: 10.1038/nmeth876
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