EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Phone: +49 6221 387-8804

Fax: +49 6221 387-8512


Total: 25 publication(s)


Politi AZ, Cai Y, Walther N, Hossain MJ, Koch B, Wachsmuth M, Ellenberg J. (2018)

Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four-dimensional imaging.

Nat Protoc 13(6):1445-1464. doi: 10.1038/nprot.2018.040
Europe PMC | doi


Germier T, Kocanova S, Walther N, Bancaud A, Shaban HA, Sellou H, Politi AZ, Ellenberg J, Gallardo F, Bystricky K. (2017)

Real-Time Imaging of a Single Gene Reveals Transcription-Initiated Local Confinement.

Biophys. J. 113(7):1383-1394. doi: 10.1016/j.bpj.2017.08.014
Europe PMC | doi

Gibeaux R, Politi AZ, Philippsen P, Nédélec F. (2017)

Mechanism of Nuclear Movements in a Multinucleated Cell.

Mol. Biol. Cell 28(3):1-33. doi: 10.1091/mbc.e16-11-0806
Europe PMC | doi


Baum K, Politi AZ, Kofahl B, Steuer R, Wolf J. (2016)

Feedback, Mass Conservation and Reaction Kinetics Impact the Robustness of Cellular Oscillations.

PLoS Comput Biol 12(12) doi: 10.1371/journal.pcbi.1005298
Europe PMC | doi

Otsuka S, Bui KH, Schorb M, Hossain MJ, Politi AZ, Koch B, Eltsov M, Beck M, Ellenberg J. (2016)

Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope

Elife 5 doi: 10.7554/eLife.19071
Europe PMC | doi

Cuylen S, Blaukopf C, Politi AZ, Müller-Reichert T, Neumann B, Poser I, Ellenberg J, Hyman AA, Gerlich DW. (2016)

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.

Nature 535(7611):308-312. doi: 10.1038/nature18610
Europe PMC | doi


Boni A, Politi AZ, Strnad P, Xiang W, Hossain MJ, Ellenberg J. (2015)

Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells.

J. Cell Biol. 209(5):705-720. doi: 10.1083/jcb.201409133
Europe PMC | doi

Letort G, Politi AZ, Ennomani H, Théry M, Nedelec F, Blanchoin L. (2015)

Geometrical and mechanical properties control actin filament organization.

PLoS Comput. Biol. 11(5) doi: 10.1371/journal.pcbi.1004245
Europe PMC | doi


Gaspers LD, Bartlett PJ, Politi A, Burnett P, Metzger W, Johnston J, Joseph SK, Höfer T, Thomas AP. (2014)

Hormone-induced calcium oscillations depend on cross-coupling with inositol 1,4,5-trisphosphate oscillations.

Cell Rep 9(4):1209-1218. doi: 10.1016/j.celrep.2014.10.033
Europe PMC | doi

Mahen R, Koch B, Wachsmuth M, Politi AZ, Perez-Gonzalez A, Mergenthaler J, Cai Y, Ellenberg J. (2014)

Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells

Mol. Biol. Cell 25(22):3610-3618. doi: 10.1091/mbc.e14-06-1091
Europe PMC | doi


Gibeaux R, Politi AZ, Nédélec F, Antony C, Knop M. (2013)

Spindle pole body-anchored Kar3 drives the nucleus along microtubules from another nucleus in preparation for nuclear fusion during yeast karyogamy

Genes Dev. 27(3):335-349. doi: 10.1101/gad.206318.112
Europe PMC | doi


Gibeaux R, Lang C, Politi AZ, Jaspersen SL, Philippsen P, Antony C. (2012)

Electron tomography of the microtubule cytoskeleton in multinucleated hyphae of Ashbya gossypii

J. Cell. Sci. 125(Pt 23):5830-5839. doi: 10.1242/jcs.111005
Europe PMC | doi


Politi AZ, Donovan GM, Tawhai MH, Sanderson MJ, Lauzon AM, Bates JH, Sneyd J. (2010)

A multiscale, spatially distributed model of asthmatic airway hyper-responsiveness.

J. Theor. Biol. 266(4):614-624. doi: 10.1016/j.jtbi.2010.07.032
Europe PMC | doi

Luijsterburg MS, von Bornstaedt G, Gourdin AM, Politi AZ, Moné MJ, Warmerdam DO, Goedhart J, Vermeulen W, van Driel R, Höfer T. (2010)

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.

J. Cell Biol. 189(3):445-463. doi: 10.1083/jcb.200909175
Europe PMC | doi

Brook BS, Peel SE, Hall IP, Politi AZ, Sneyd J, Bai Y, Sanderson MJ, Jensen OE. (2010)

A biomechanical model of agonist-initiated contraction in the asthmatic airway.

Respir Physiol Neurobiol 170(1):44-58. doi: 10.1016/j.resp.2009.11.006
Europe PMC | doi


Cooper PR, McParland BE, Mitchell HW, Noble PB, Politi AZ, Ressmeyer AR, West AR. (2009)

Airway mechanics and methods used to visualize smooth muscle dynamics in vitro.

Pulm Pharmacol Ther 22(5):398-406. doi: 10.1016/j.pupt.2008.09.008
Europe PMC | doi

Bates JH, Bullimore SR, Politi AZ, Sneyd J, Anafi RC, Lauzon AM. (2009)

Transient oscillatory force-length behavior of activated airway smooth muscle.

Am. J. Physiol. Lung Cell Mol. Physiol. 297(2):L362-72. doi: 10.1152/ajplung.00095.2009
Europe PMC | doi

Bullimore SR, Lauzon AM, Politi AZ, Anafi RC, Sneyd J, Bates JHT. (2009)

Effect of Deep Inspirations on Airway Smooth Muscle Force


Donovan GM, Politi AZ, Sneyd J, Tawhai MH. (2009)

A Multiscale, Spatially-Distributed Model of Airway Hyper-Responsiveness.


Politi AZ, Bullimore SR, Lauzon AM, Bates JH, Sneyd J. (2009)

A Model of Cross-Linked Filaments Accounts for the Passive Properties of Airway Smooth Muscle



Wang I, Politi AZ, Tania N, Bai Y, Sanderson MJ, Sneyd J. (2008)

A mathematical model of airway and pulmonary arteriole smooth muscle.

Biophys. J. 94(6):2053-2064. doi: 10.1529/biophysj.107.113977
Europe PMC | doi

Salazar C, Politi AZ, Höfer T. (2008)

Decoding of calcium oscillations by phosphorylation cycles: analytic results.

Biophys. J. 94(4):1203-1215. doi: 10.1529/biophysj.107.113084
Europe PMC | doi


Politi A, Gaspers LD, Thomas AP, Höfer T. (2006)

Models of IP3 and Ca2+ oscillations: frequency encoding and identification of underlying feedbacks.

Biophys. J. 90(9):3120-3133. doi: 10.1529/biophysj.105.072249
Europe PMC | doi


Politi A, Moné MJ, Houtsmuller AB, Hoogstraten D, Vermeulen W, Heinrich R, van Driel R. (2005)

Mathematical modeling of nucleotide excision repair reveals efficiency of sequential assembly strategies.

Mol. Cell 19(5):679-690. doi: 10.1016/j.molcel.2005.06.036
Europe PMC | doi


Höfer T, Politi A, Heinrich R. (2001)

Intercellular Ca2+ wave propagation through gap-junctional Ca2+ diffusion: a theoretical study.

Biophys. J. 80(1):75-87. doi: 10.1016/s0006-3495(01)75996-6
Europe PMC | doi