Total: 52 publication(s)


Ryu JK, Katan AJ, van der Sluis EO, Wisse T, de Groot R, Haering CH, Dekker C. (2020)

Publisher correction: the condensin holocomplex cycles dynamically between open and collapsed states.

Nat Struct Mol Biol 27(12) doi: 10.1038/s41594-020-00524-y
Europe PMC | doi

Ryu JK, Katan AJ, van der Sluis EO, Wisse T, de Groot R, Haering CH, Dekker C. (2020)

The condensin holocomplex cycles dynamically between open and collapsed states.

Nat Struct Mol Biol 27(12):1134-1141. doi: 10.1038/s41594-020-0508-3
Europe PMC | doi

Datta S, Lecomte L, Haering CH. (2020)

Structural insights into DNA loop extrusion by SMC protein complexes.

Curr. Opin. Struct. Biol. 65:102-109. doi: 10.1016/
Europe PMC | doi

Kim E, Kerssemakers J, Shaltiel IA, Haering CH, Dekker C. (2020)

DNA-loop extruding condensin complexes can traverse one another.

Nature 579(7799):438-442. doi: 10.1038/s41586-020-2067-5
Europe PMC | doi

Lee B-G, Merkel F, Allegretti M, Hassler M, Cawood C, Lecomte L, O'Reilly FJ, Sinn LR, Gutierrez-Escribano P, Kschonsak M, Bravo S, Nakane T, Rappsilber J, Aragon L, Beck M, Löwe J, Haering CH. (2020)

Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.

Nat Struct Mol Biol 27(8):743-751. doi: 10.1038/s41594-020-0457-x
Europe PMC | doi


Elbatsh AMO, Kim E, Eeftens JM, Raaijmakers JA, van der Weide RH, García-Nieto A, Bravo S, Ganji M, Uit de Bos J, Teunissen H, Medema RH, de Wit E, Haering CH, Dekker C, Rowland BD. (2019)

Distinct roles for condensin's two ATPase sites in chromosome condensation.

Mol. Cell 76(5):724-737.e5. doi: 10.1016/j.molcel.2019.09.020
Europe PMC | doi

Manalastas-Cantos K, M, Haering CH, Svergun DI. (2019)

Solution structure and flexibility of the condensin HEAT-repeat subunit Ycg1.

J. Biol. Chem. 294(37):13822-13829. doi: 10.1074/jbc.RA119.008661
Europe PMC | doi

Hassler M, Shaltiel IA, Kschonsak M, Simon B, Merkel F, Thärichen L, Bailey HJ, Macošek J, Bravo S, Metz J, Hennig J, Haering CH. (2019)

Structural basis of an asymmetric condensin ATPase cycle.

Mol. Cell 74(6):1175-1188.e9. doi: 10.1016/j.molcel.2019.03.037
Europe PMC | doi

Bisht S, Haering CH. (2019)

Twist to disentangle.

Nat. Struct. Mol. Biol. 26(4):252-253. doi: 10.1038/s41594-019-0209-y
Europe PMC | doi


Hassler M, Shaltiel IA, Haering CH. (2018)

Towards a unified model of SMC complex function.

Curr. Biol. 28(21):R1266-R1281. doi: 10.1016/j.cub.2018.08.034
Europe PMC | doi

Hocquet C, Robellet X, Modolo L, Sun X-M, Burny C, Cuylen-Haering S, Toselli E, Clauder-Munster S, Steinmetz L, Haering CH, Marguerat S, Bernard P. (2018)

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

Elife e38517 doi: 10.7554/eLife.38517
Europe PMC | doi

Li Y, Muir K, Bowler MW, Metz J, Haering CH, Panne D. (2018)

Structural basis for Scc3-dependent cohesin recruitment to chromatin.

Elife 7 doi: 10.7554/eLife.38356
Europe PMC | doi

Schiklenk C, Petrova B, Kschonsak M, Hassler M, Klein C, Gibson TJ, Haering CH. (2018)

Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1

Journal of Cell Biology 217(7) doi: 10.1083/jcb.201711097
Europe PMC | doi

Ganji M, Shaltiel IA, Bisht S, Kim E, Kalichava A, Haering CH, Dekker C. (2018)

Real-time imaging of DNA loop extrusion by condensin.

Science 360(6384) doi: 10.1126/science.aar7831
Europe PMC | doi


Eeftens JM, Bisht S, Kerssemakers J, Kschonsak M, Haering CH, Dekker C. (2017)

Real-time detection of condensin-driven DNA compaction reveals a multistep binding mechanism.

EMBO J. 36(23):3448-3457. doi: 10.15252/embj.201797596
Europe PMC | doi

Terakawa T, Bisht S, Eeftens JM, Dekker C, Haering CH, Greene EC. (2017)

The condensin complex is a mechanochemical motor that translocates along DNA

Science 358(6363):672-676. doi: 10.1126/science.aan6516
Europe PMC | doi

Schwarzer W, Abdennur N, Goloborodko A, Pekowska A, Fudenberg G, Loe-Mie Y, Fonseca NA, Huber W, Haering CH, Mirny L, Spitz F. (2017)

Two independent modes of chromatin organization revealed by cohesin removal

Nature 551(7678):51-56. doi: 10.1038/nature24281
Europe PMC | doi

Kschonsak M, Merkel F, Bisht S, Metz J, Rybin V, Hassler M, Haering CH. (2017)

Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.

Cell 171(3):588-600. doi: 10.1016/j.cell.2017.09.008
Europe PMC | doi

Schiklenk C, Petrova B, Haering CH. (2017)

A Protocol for Measuring Mitotic Chromosome Condensation Quantitatively in Fission Yeast Cells.

Methods Mol. Biol. 1515:245-255. doi: 10.1007/978-1-4939-6545-8_15
Europe PMC | doi


Toselli-Mollereau E, Robellet X, Fauque L, Lemaire S, Schiklenk C, Klein C, Hocquet C, Legros P, N'Guyen L, Mouillard L, Chautard E, Auboeuf D, Haering CH, Bernard P. (2016)

Nucleosome eviction in mitosis assists condensin loading and chromosome condensation

EMBO J. 35(14):1565-1581. doi: 10.15252/embj.201592849
Europe PMC | doi

Muir KW, Kschonsak M, Li Y, Metz J, Haering CH, Panne D. (2016)

Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function.

Cell Rep 14(9):2116-2126. doi: 10.1016/j.celrep.2016.01.078
Europe PMC | doi

Eeftens JM, Katan AJ, Kschonsak M, Hassler M, de Wilde L, Dief EM, Haering CH, Dekker C. (2016)

Condensin Smc2-Smc4 Dimers Are Flexible and Dynamic.

Cell Rep 14(8):1813-1818. doi: 10.1016/j.celrep.2016.01.063
Europe PMC | doi

Haering CH, Gruber S. (2016)

SnapShot: SMC Protein Complexes Part II.

Cell 164(4):818-818.e1. doi: 10.1016/j.cell.2016.01.052
Europe PMC | doi

Haering CH, Gruber S. (2016)

SnapShot: SMC Protein Complexes Part I.

Cell 164(1-2):326-326.e1. doi: 10.1016/j.cell.2015.12.026
Europe PMC | doi


Kschonsak M, Haering CH. (2015)

Shaping mitotic chromosomes: From classical concepts to molecular mechanisms.

Bioessays 37(7) doi: 10.1002/bies.201500020
Europe PMC | doi

Frosi Y, Haering CH. (2015)

Control of chromosome interactions by condensin complexes.

Curr. Opin. Cell Biol. 34:94-100. doi: 10.1016/
Europe PMC | doi


Hériché JK, Lees JG, Morilla I, Walter T, Petrova B, Roberti MJ, Hossain MJ, Adler P, Fernández JM, Krallinger M, Haering CH, Vilo J, Valencia A, Ranea JA, Orengo C, Ellenberg J. (2014)

Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation

Mol. Biol. Cell 25(16):2522-2536. doi: 10.1091/mbc.e13-04-0221
Europe PMC | doi

Piazza I, Rutkowska A, Ori A, Walczak M, Metz J, Pelechano V, Beck M, Haering CH. (2014)

Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits

Nat. Struct. Mol. Biol. 21(6):560-568. doi: 10.1038/nsmb.2831
Europe PMC | doi


Cuylen S, Metz J, Hruby A, Haering CH. (2013)

Entrapment of chromosomes by condensin rings prevents their breakage during cytokinesis

Dev. Cell 27(4):469-478. doi: 10.1016/j.devcel.2013.10.018
Europe PMC | doi

Piazza I, Haering CH, Rutkowska A. (2013)

Condensin: crafting the chromosome landscape

Chromosoma 122(3):175-190. doi: 10.1007/s00412-013-0405-1
Europe PMC | doi

Petrova B, Dehler S, Kruitwagen T, Hériché JK, Miura K, Haering CH. (2013)

Quantitative analysis of chromosome condensation in fission yeast

Mol. Cell. Biol. 33(5):984-998. doi: 10.1128/mcb.01400-12
Europe PMC | doi

Haering CH, Losada A. (2013)

Understanding chromatin and chromosomes: from static views to dynamic thinking

EMBO Rep. 14(2):109-111. doi: 10.1038/embor.2012.221
Europe PMC | doi


Haering CH, Jessberger R. (2012)

Cohesin in determining chromosome architecture

Exp. Cell Res. 318(12):1386-1393. doi: 10.1016/j.yexcr.2012.03.016
Europe PMC | doi


Rutkowska A, Haering CH, Schultz C. (2011)

A FlAsH-based cross-linker to study protein interactions in living cells

Angew. Chem. Int. Ed. Engl. 50(52):12655-12658. doi: 10.1002/anie.201106404
Europe PMC | doi

Petrova B, Haering CH. (2011)

Condensin engages chromatin

Chembiochem 12(16):2399-2401. doi: 10.1002/cbic.201100531
Europe PMC | doi

Cuylen S, Haering CH. (2011)

Deciphering condensin action during chromosome segregation

Trends Cell Biol. 21(9):552-559. doi: 10.1016/j.tcb.2011.06.003
Europe PMC | doi

Cuylen S, Metz J, Haering CH. (2011)

Condensin structures chromosomal DNA through topological links

Nat. Struct. Mol. Biol. 18(8):894-901. doi: 10.1038/nsmb.2087
Europe PMC | doi

Kurze A, Michie KA, Dixon SE, Mishra A, Itoh T, Khalid S, Strmecki L, Shirahige K, Haering CH, Löwe J, Nasmyth K. (2011)

A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion

EMBO J. 30(2):364-378. doi: 10.1038/emboj.2010.315
Europe PMC | doi


Cuylen S, Haering CH. (2010)

A new cohesive team to mediate DNA looping

Cell Stem Cell 7(4):424-426. doi: 10.1016/j.stem.2010.09.006
Europe PMC | doi


. (2009)

Keeping replicated chromatids together until mitosis

In: Lynne S Cox, Molecular Themes in Eukaryotic DNA Replication. pp 269-296.doi: 978-0-85404-164-0

Haering CH. (2009)

Foreword: the many fascinating functions of SMC protein complexes

Chromosome Res. 17(2):127-129. doi: 10.1007/s10577-008-9008-8
Europe PMC | doi

Nasmyth K, Haering CH. (2009)

Cohesin: its roles and mechanisms

Annu. Rev. Genet. 43:525-558. doi: 10.1146/annurev-genet-102108-134233
Europe PMC | doi


Haering CH, Farcas AM, Arumugam P, Metson J, Nasmyth K. (2008)

The cohesin ring concatenates sister DNA molecules

Nature 454(7202):297-301. doi: 10.1038/nature07098
Europe PMC | doi


Arumugam P, Nishino T, Haering CH, Gruber S, Nasmyth K. (2006)

Cohesin's ATPase activity is stimulated by the C-terminal Winged-Helix domain of its kleisin subunit

Curr. Biol. 16(20):1998-2008. doi: 10.1016/j.cub.2006.09.002
Europe PMC | doi


Nasmyth K, Haering CH. (2005)

The structure and function of SMC and kleisin complexes

Annu. Rev. Biochem. 74:595-648. doi: 10.1146/annurev.biochem.74.082803.133219
Europe PMC | doi


Haering CH, Schoffnegger D, Nishino T, Helmhart W, Nasmyth K, Löwe J. (2004)

Structure and stability of cohesin's Smc1-kleisin interaction

Mol. Cell 15(6):951-964. doi: 10.1016/j.molcel.2004.08.030
Europe PMC | doi


Haering CH, Nasmyth K. (2003)

Building and breaking bridges between sister chromatids

Bioessays 25(12):1178-1191. doi: 10.1002/bies.10361
Europe PMC | doi

Arumugam P, Gruber S, Tanaka K, Haering CH, Mechtler K, Nasmyth K. (2003)

ATP hydrolysis is required for cohesin's association with chromosomes

Curr. Biol. 13(22):1941-1953. doi: 10.1016/j.cub.2003.10.036
Europe PMC | doi

Gruber S, Haering CH, Nasmyth K. (2003)

Chromosomal cohesin forms a ring

Cell 112(6):765-777. doi: 10.1016/s0092-8674(03)00162-4
Europe PMC | doi


Haering CH, Löwe J, Hochwagen A, Nasmyth K. (2002)

Molecular architecture of SMC proteins and the yeast cohesin complex

Mol. Cell 9(4):773-788. doi: 10.1016/s1097-2765(02)00515-4
Europe PMC | doi

Ivanov D, Schleiffer A, Eisenhaber F, Mechtler K, Haering CH, Nasmyth K. (2002)

Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion

Curr. Biol. 12(4):323-328. doi: 10.1016/s0960-9822(02)00681-4
Europe PMC | doi


Haering CH, Nakamura TM, Baumann P, Cech TR. (2000)

Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomycespombe

Proc. Natl. Acad. Sci. U.S.A. 97(12):6367-6372. doi: 10.1073/pnas.130187397
Europe PMC | doi