EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
Biography
PhD 1998, Freie Universität Berlin, Germany
Predoctoral and postdoctoral research at the National Institutes of Health (NIH), Bethesda, USA
Group leader at EMBL since 1999.
Head of Gene Expression Unit 2006-2010.
Head of Cell Biology and Biophysics Unit since 2010.
ERC Advanced Investigator since 2016.
Publications
Total: 172 publication(s)
2021
Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Fernández XM, Figlerowicz M, Gasser SM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Lichter P, Linnarsson S, Marine JC, Marioni JC, Marti-Renom MA, Netea MG, Nickel D, Nollmann M, Novak HR, Parkinson H, Piccolo S, Pinheiro I, Pombo A, Popp C, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Theis FJ, Torres-Padilla ME, Valencia A, Vallot C, van Oudenaarden A, Vidal M, Voet T, LifeTime Community Working Groups. (2021)
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine.
Nature doi: 10.1038/s41586-021-03287-8
Europe PMC | doi
2020
Schueder F, Lara-Gutiérrez J, Haas D, Beckwith KS, Yin P, Ellenberg J, Jungmann R. (2020)
Super-resolution spatial proximity detection with proximity-PAINT.
Angew Chem Int Ed Engl 60(2):716-720. doi: 10.1002/anie.202009031
Europe PMC | doi
Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Fernández XM, Figlerowicz M, Gasser SM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Lichter P, Linnarsson S, Marine JC, Marioni J, Marti-Renom MA, Netea MG, Nickel D, Nollmann M, Novak HR, Parkinson H, Piccolo S, Pinheiro I, Pombo A, Popp C, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Theis FJ, Torres-Padilla ME, Valencia A, Vallot C, van Oudenaarden A, Vidal M, Voet T. (2020)
Life time and improving European healthcare through cell-based interceptive medicine.
Nature 587(7834):377-386. doi: 10.1038/s41586-020-2715-9
Europe PMC | doi
Farrants H, Tarnawski M, Müller TG, Otsuka S, Hiblot J, Koch B, Kueblbeck M, Kräusslich HG, Ellenberg J, Johnsson K. (2020)
Chemogenetic control of nanobodies.
Nat. Methods 17(3):279-282. doi: 10.1038/s41592-020-0746-7
Europe PMC | doi
Gwosch KC, Pape JK, Balzarotti F, Hoess P, Ellenberg J, Ries J, Hell SW. (2020)
MINFLUX nanoscopy delivers 3D multicolor nanometer resolution in cells.
Nat Methods 17(2):217-224. doi: 10.1038/s41592-019-0688-0
Europe PMC | doi
2019
Thevathasan JV, Kahnwald M, Cieśliński K, Hoess P, Peneti SK, Reitberger M, Heid D, Kasuba KC, Hoerner SJ, Li Y, Wu YL, Mund M, Matti U, Pereira PM, Henriques R, Kueblbeck M, Nijmeijer B, Ellenberg J, Sabinina VJ, Ries J. (2019)
Nuclear pores as versatile reference standards for quantitative superresolution microscopy.
Nat. Methods 16(10):1045-1053. doi: 10.1038/s41592-019-0574-9
Europe PMC | doi
Thevathasan JV, Kahnwald M, Cieśliński K, Hoess P, Peneti SK, Reitberger M, Heid D, Kasuba KC, Hoerner SJ, Li Y, Wu YL, Mund M, Matti U, Pereira PM, Henriques R, Kueblbeck M, Nijmeijer B, Ellenberg J, Sabinina VJ, Ries J. (2019)
Publisher correction: nuclear pores as versatile reference standards for quantitative superresolution microscopy.
Nat Methods 16(12) doi: 10.1038/s41592-019-0659-5
Europe PMC | doi
Frei MS, Hoess P, Lampe M, Nijmeijer B, Kueblbeck M, Ellenberg J, Wadepohl H, Ries J, Pitsch S, Reymond L, Johnsson K. (2019)
Photoactivation of silicon rhodamines via a light-induced protonation.
Nat Commun 10(1) doi: 10.1038/s41467-019-12480-3
Europe PMC | doi
Schlichthaerle T, Strauss MT, Schueder F, Auer A, Nijmeijer B, Kueblbeck M, Sabinina VJ, Thevathasan JV, Ries J, Ellenberg J, Jungmann R. (2019)
Direct visualization of single nuclear pore complex proteins using genetically-encoded probes for DNA-PAINT.
Angew. Chem. Int. Ed. Engl. 58(37):13004-13008. doi: 10.1002/anie.201905685
Europe PMC | doi
Cattoglio C, Pustova I, Walther N, Ho JJ, Hantsche-Grininger M, Inouye CJ, Hossain MJ, Dailey GM, Ellenberg J, Darzacq X, Tjian R, Hansen AS. (2019)
Determining cellular CTCF and cohesin abundances to constrain 3D genome models.
Elife 8 doi: 10.7554/eLife.40164
Europe PMC | doi
Holzmann J, Politi AZ, Nagasaka K, Hantsche-Grininger M, Walther N, Koch B, Fuchs J, Dürnberger G, Tang W, Ladurner R, Stocsits RR, Busslinger GA, Novák B, Mechtler K, Davidson IF, Peters JM, Ellenberg J. (2019)
Absolute quantification of cohesin, CTCF and their regulators in human cells.
Elife 8 doi: 10.7554/eLife.46269
Europe PMC | doi
Schneider I, Ellenberg J. (2019)
Mysteries in embryonic development: how can errors arise so frequently at the beginning of mammalian life?
PLoS Biol. 17(3) doi: 10.1371/journal.pbio.3000173
Europe PMC | doi
Heriche JK, Alexander S, Ellenberg J. (2019)
Integrating imaging and omics: computational methods and challenges.
Annu Rev Biomed Data Sci 2:175-197. doi: 10.1146/annurev-biodatasci-080917-013328
doi
2018
Pękowska A, Klaus B, Xiang W, Severino J, Daigle N, Klein FA, Oleś M, Casellas R, Ellenberg J, Steinmetz LM, Bertone P, Huber W. (2018)
Gain of CTCF-anchored chromatin loops marks the exit from naive pluripotency.
Cell Syst 7(5):482-495. doi: 10.1016/j.cels.2018.09.003
Europe PMC | doi
Ellenberg J, Swedlow JR, Barlow M, Cook CE, Sarkans U, Patwardhan A, Brazma A, Birney E. (2018)
A call for public archives for biological image data.
Nat. Methods 15(11):849-854. doi: 10.1038/s41592-018-0195-8
Europe PMC | doi
Popovic D, Koch B, Kueblbeck M, Ellenberg J, Pelkmans L. (2018)
Multivariate control of transcript to protein variability in single mammalian cells.
Cell Syst 7(4):398-411. doi: 10.1016/j.cels.2018.09.001
Europe PMC | doi
Strauss S, Nickels PC, Strauss MT, Jimenez Sabinina V, Ellenberg J, Carter JD, Gupta S, Janjic N, Jungmann R. (2018)
Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging.
Nat Methods 15(9) doi: 10.1038/s41592-018-0105-0
Europe PMC | doi
Cai Y, Hossain MJ, Hériché JK, Politi AZ, Walther N, Koch B, Wachsmuth M, Nijmeijer B, Kueblbeck M, Martinic-Kavur M, Ladurner R, Alexander S, Peters JM, Ellenberg J. (2018)
Experimental and computational framework for a dynamic protein atlas of human cell division.
Nature 561(7723) doi: 10.1038/s41586-018-0518-z
Europe PMC | doi
Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Hériché JK, Wutz G, van der Lelij P, Kreidl E, Hutchins JR, Axelsson-Ekker H, Ellenberg J, Hyman AA, Peters JM, Mechtler K. (2018)
The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.
EMBO J. 37(15) doi: 10.15252/embj.201797150
Europe PMC | doi
Reichmann J, Nijmeijer B, Hossain MJ, Eguren M, Schneider I, Politi AZ, Roberti MJ, Hufnagel L, Hiiragi T, Ellenberg J. (2018)
Dual-spindle formation in zygotes keeps parental genomes apart in early mammalian embryos.
Science 361(6398):189-193. doi: 10.1126/science.aar7462
Europe PMC | doi
Walther N, Hossain MJ, Politi AZ, Koch B, Kueblbeck M, Ødegård-Fougner Ø, Lampe M, Ellenberg J. (2018)
A quantitative map of human Condensins provides new insights into mitotic chromosome architecture.
J Cell Biol 217(7) doi: 10.1083/jcb.201801048
Europe PMC | doi
Koch B, Nijmeijer B, Kueblbeck M, Cai Y, Walther N, Ellenberg J. (2018)
Generation and validation of homozygous fluorescent knock-in cells using CRISPR-Cas9 genome editing.
Nat Protoc 13(6):1465-1487. doi: 10.1038/nprot.2018.042
Europe PMC | doi
Politi AZ, Cai Y, Walther N, Hossain MJ, Koch B, Wachsmuth M, Ellenberg J. (2018)
Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four-dimensional imaging.
Nat Protoc 13(6):1445-1464. doi: 10.1038/nprot.2018.040
Europe PMC | doi
iNEXT Consortium. (2018)
iNEXT: a European facility network to stimulate translational structural biology.
FEBS Lett. 592(12) doi: 10.1002/1873-3468.13062
Europe PMC | doi
Xiang W, Roberti MJ, Hériché JK, Huet S, Alexander S, Ellenberg J. (2018)
Correction: Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.
J Cell Biol 217(9):3315-3316. doi: 10.1083/JCB.20170907408082018c
Europe PMC | doi
Xiang W, Roberti MJ, Hériché JK, Huet S, Alexander S, Ellenberg J. (2018)
Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.
J Cell Biol 217(6) doi: 10.1083/jcb.201709074
Europe PMC | doi
Li Y, Mund M, Hoess P, Deschamps J, Matti U, Nijmeijer B, Sabinina VJ, Ellenberg J, Schoen I, Ries J. (2018)
Real-time 3D single-molecule localization using experimental point spread functions.
Nat Methods 15(5) doi: 10.1038/nmeth.4661
Europe PMC | doi
Reichmann J, Eguren M, Lin Y, Schneider I, Ellenberg J. (2018)
Live imaging of cell division in preimplantation mouse embryos using inverted light-sheet microscopy.
Methods Cell Biol. 145:279-292. doi: 10.1016/bs.mcb.2018.03.030
Europe PMC | doi
Walther N, Ellenberg J. (2018)
Quantitative live and super-resolution microscopy of mitotic chromosomes
Methods Cell Biol. 145 doi: 10.1016/bs.mcb.2018.03.014
Europe PMC | doi
Barton C, Morganella S, Ødegård-Fougner Ø, Alexander S, Ries J, Fitzgerald T, Ellenberg J, Birney E. (2018)
ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy.
PLoS Comput Biol 14(3) doi: 10.1371/journal.pcbi.1006002
Europe PMC | doi
Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T. (2018)
Author Correction: Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.
Nat. Cell Biol. 20(4) doi: 10.1038/s41556-018-0044-0
Europe PMC | doi
Otsuka S, Ellenberg J. (2018)
Mechanisms of nuclear pore complex assembly: Two different ways of building one molecular machine
FEBS letters 592(4) doi: 10.1002/1873-3468.12905
Europe PMC | doi
Otsuka S, Steyer AM, Schorb M, Hériché JK, Hossain MJ, Sethi S, Kueblbeck M, Schwab Y, Beck M, Ellenberg J. (2018)
Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings
Nat. Struct. Mol. Biol. 25(1):21-28. doi: 10.1038/s41594-017-0001-9
Europe PMC | doi
2017
Wutz G, Várnai C, Nagasaka K, Cisneros DA, Stocsits RR, Tang W, Schoenfelder S, Jessberger G, Muhar M, Hossain MJ, Walther N, Koch B, Kueblbeck M, Ellenberg J, Zuber J, Fraser P, Peters JM. (2017)
Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.
EMBO J. 36(24) doi: 10.15252/embj.201798004
Europe PMC | doi
Germier T, Kocanova S, Walther N, Bancaud A, Shaban HA, Sellou H, Politi AZ, Ellenberg J, Gallardo F, Bystricky K. (2017)
Real-Time Imaging of a Single Gene Reveals Transcription-Initiated Local Confinement.
Biophys. J. 113(7):1383-1394. doi: 10.1016/j.bpj.2017.08.014
Europe PMC | doi
Yiming Li, Markus Mund, Philipp Hoess, Ulf Matti, Bianca Nijmeijer, Vilma Jimenez Sabinina, Jan Ellenberg, Ingmar Schoen, Jonas Ries. (2017)
Fast, robust and precise 3D localization for arbitrary point spread functions.
bioRxiv doi: 10.1101/172643
doi
2016
S Pedersen R, Karemore G, Gudjonsson T, Rask MB, Neumann B, Hériché JK, Pepperkok R, Ellenberg J, Gerlich DW, Lukas J, Lukas C. (2016)
Profiling DNA damage response following mitotic perturbations.
Nat Commun 7(13887):1-12. doi: 10.1038/ncomms13887
Europe PMC | doi
Otsuka S, Bui KH, Schorb M, Hossain MJ, Politi AZ, Koch B, Eltsov M, Beck M, Ellenberg J. (2016)
Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope
Elife 5 doi: 10.7554/eLife.19071
Europe PMC | doi
Uhlen M, Bandrowski A, Carr S, Edwards A, Ellenberg J, Lundberg E, Rimm DL, Rodriguez H, Hiltke T, Snyder M, Yamamoto T. (2016)
A proposal for validation of antibodies.
Nat. Methods 13(10) doi: 10.1038/nmeth.3995
Europe PMC | doi
Cuylen S, Blaukopf C, Politi AZ, Müller-Reichert T, Neumann B, Poser I, Ellenberg J, Hyman AA, Gerlich DW. (2016)
Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.
Nature 535(7611):308-312. doi: 10.1038/nature18610
Europe PMC | doi
Saliba AE, Vonkova I, Deghou S, Ceschia S, Tischer C, Kugler KG, Bork P, Ellenberg J, Gavin AC. (2016)
A protocol for the systematic and quantitative measurement of protein-lipid interactions using the liposome-microarray-based assay.
Nat Protoc 11(6):1021-1038. doi: 10.1038/nprot.2016.059
Europe PMC | doi
Jupp S, Malone J, Burdett T, Heriche JK, Williams E, Ellenberg J, Parkinson H, Rustici G. (2016)
The cellular microscopy phenotype ontology.
J Biomed Semantics 7:28. doi: 10.1186/s13326-016-0074-0
Europe PMC | doi
Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T. (2016)
Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.
Nat. Cell Biol. 18(6):692-699. doi: 10.1038/ncb3353
Europe PMC | doi
Isokane M, Walter T, Mahen R, Nijmeijer B, Hériché JK, Miura K, Maffini S, Ivanov MP, Kitajima TS, Peters JM, Ellenberg J. (2016)
ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.
J. Cell Biol. 212(6):647-659. doi: 10.1083/jcb.201408089
Europe PMC | doi
Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de Medeiros G, Norlin N, Hiiragi T, Hufnagel L, Ellenberg J. (2016)
Inverted light-sheet microscope for imaging mouse pre-implantation development.
Nat. Methods 13(2):139-142. doi: 10.1038/nmeth.3690
Europe PMC | doi
2015
Mardin BR, Drainas AP, Waszak SM, Weischenfeldt J, Isokane M, Stütz AM, Raeder B, Efthymiopoulos T, Buccitelli C, Segura-Wang M, Northcott P, Pfister SM, Lichter P, Ellenberg J, Korbel JO. (2015)
A cell-based model system links chromothripsis with hyperploidy.
Mol. Syst. Biol. 11(9):828. doi: 10.15252/msb.20156505
Europe PMC | doi
Vonkova I, Saliba AE, Deghou S, Anand K, Ceschia S, Doerks T, Galih A, Kugler KG, Maeda K, Rybin V, van Noort V, Ellenberg J, Bork P, Gavin AC. (2015)
Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains.
Cell Rep 12(9):1519-1530. doi: 10.1016/j.celrep.2015.07.054
Europe PMC | doi
Metchat A, Eguren M, Hossain JM, Politi AZ, Huet S, Ellenberg J. (2015)
An actin-dependent spindle position checkpoint ensures the asymmetric division in mouse oocytes (Retraction of vol 6, 7784, 2015)
Nat Commun 6 doi: 10.1038/ncomms9124
Europe PMC | doi
Boni A, Politi AZ, Strnad P, Xiang W, Hossain MJ, Ellenberg J. (2015)
Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells.
J. Cell Biol. 209(5):705-720. doi: 10.1083/jcb.201409133
Europe PMC | doi
Wachsmuth M, Conrad C, Bulkescher J, Koch B, Mahen R, Isokane M, Pepperkok R, Ellenberg J. (2015)
High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.
Nat. Biotechnol. 33(4):384-389. doi: 10.1038/nbt.3146
Europe PMC | doi
Lees JG, Hériché JK, Morilla I, Fernández JM, Adler P, Krallinger M, Vilo J, Valencia A, Ellenberg J, Ranea JA, Orengo C. (2015)
FUN-L: Gene prioritization for RNAi screens.
Bioinformatics 31(12):2052-2053. doi: 10.1093/bioinformatics/btv073
Europe PMC | doi
Solc P, Kitajima TS, Yoshida S, Brzakova A, Kaido M, Baran V, Mayer A, Samalova P, Motlik J, Ellenberg J. (2015)
Multiple Requirements of PLK1 during Mouse Oocyte Maturation.
PLoS ONE 10(2) doi: 10.1371/journal.pone.0116783
Europe PMC | doi
2014
van der Lelij P, Stocsits RR, Ladurner R, Petzold G, Kreidl E, Koch B, Schmitz J, Neumann B, Ellenberg J, Peters JM. (2014)
SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs
EMBO J. 33(22):2643-2658. doi: 10.15252/embj.201488202
Europe PMC | doi
Mahen R, Koch B, Wachsmuth M, Politi AZ, Perez-Gonzalez A, Mergenthaler J, Cai Y, Ellenberg J. (2014)
Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells
Mol. Biol. Cell 25(22):3610-3618. doi: 10.1091/mbc.e14-06-1091
Europe PMC | doi
Rohn JL, Patel JV, Neumann B, Bulkescher J, Mchedlishvili N, McMullan RC, Quintero OA, Ellenberg J, Baum B. (2014)
Myo19 Ensures Symmetric Partitioning of Mitochondria and Coupling of Mitochondrial Segregation to Cell Division.
Curr. Biol. 24(21):2598-2605. doi: 10.1016/j.cub.2014.09.045
Europe PMC | doi
Tegha-Dunghu J, Bausch E, Neumann B, Wuensche A, Walter T, Ellenberg J, Gruss OJ. (2014)
MAP1S controls microtubule stability throughout the cell cycle in human cells.
J. Cell. Sci. 127(23):5007-5013. doi: 10.1242/jcs.136457
Europe PMC | doi
Hériché JK, Lees JG, Morilla I, Walter T, Petrova B, Roberti MJ, Hossain MJ, Adler P, Fernández JM, Krallinger M, Haering CH, Vilo J, Valencia A, Ranea JA, Orengo C, Ellenberg J. (2014)
Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation
Mol. Biol. Cell 25(16):2522-2536. doi: 10.1091/mbc.e13-04-0221
Europe PMC | doi
Keller D, Orpinell M, Olivier N, Wachsmuth M, Mahen R, Wyss R, Hachet V, Ellenberg J, Manley S, Gönczy P. (2014)
Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells
J. Cell Biol. 204(5):697-712. doi: 10.1083/jcb.201307049
Europe PMC | doi
Otsuka S, Szymborska A, Ellenberg J. (2014)
Imaging the assembly, structure, and function of the nuclear pore inside cells.
Methods Cell Biol. 122:219-238. doi: 10.1016/b978-0-12-417160-2.00010-2
Europe PMC | doi
Saliba AE, Vonkova I, Ceschia S, Findlay GM, Maeda K, Tischer C, Deghou S, van Noort V, Bork P, Pawson T, Ellenberg J, Gavin AC. (2014)
A quantitative liposome microarray to systematically characterize protein-lipid interactions
Nat. Methods 11(1):47-50. doi: 10.1038/nmeth.2734
Europe PMC | doi
2013
Walter A, Chapuis C, Huet S, Ellenberg J. (2013)
Crowded chromatin is not sufficient for heterochromatin formation and not required for its maintenance
J. Struct. Biol. 184(3):445-453. doi: 10.1016/j.jsb.2013.10.004
Europe PMC | doi
Tedeschi A, Wutz G, Huet S, Jaritz M, Wuensche A, Schirghuber E, Davidson IF, Tang W, Cisneros DA, Bhaskara V, Nishiyama T, Vaziri A, Wutz A, Ellenberg J, Peters JM. (2013)
Wapl is an essential regulator of chromatin structure and chromosome segregation
Nature 501(7468):564-568. doi: 10.1038/nature12471
Europe PMC | doi
Szymborska A, de Marco A, Daigle N, Cordes VC, Briggs JA, Ellenberg J. (2013)
Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging
Science 341(6146):655-658. doi: 10.1126/science.1240672
Europe PMC | doi
Mardin BR, Isokane M, Cosenza MR, Krämer A, Ellenberg J, Fry AM, Schiebel E. (2013)
EGF-induced centrosome separation promotes mitotic progression and cell survival
Dev. Cell 25(3):229-240. doi: 10.1016/j.devcel.2013.03.012
Europe PMC | doi
Pau G, Walter T, Neumann B, Hériché JK, Ellenberg J, Huber W. (2013)
Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay.
BMC Bioinformatics 14:308. doi: 10.1186/1471-2105-14-308
Europe PMC | doi
2012
Bancaud A, Lavelle C, Huet S, Ellenberg J. (2012)
A fractal model for nuclear organization: current evidence and biological implications
Nucleic Acids Res. 40(18):8783-8792. doi: 10.1093/nar/gks586
Europe PMC | doi
Mall M, Walter T, Gorjánácz M, Davidson IF, Nga Ly-Hartig TB, Ellenberg J, Mattaj IW. (2012)
Mitotic lamin disassembly is triggered by lipid-mediated signaling
J. Cell Biol. 198(6):981-990. doi: 10.1083/jcb.201205103
Europe PMC | doi
Courtois A, Schuh M, Ellenberg J, Hiiragi T. (2012)
The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development
J. Cell Biol. 198(3):357-370. doi: 10.1083/jcb.201202135
Europe PMC | doi
Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R. (2012)
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway
Nat. Cell Biol. 14(7):764-774. doi: 10.1038/ncb2510
Europe PMC | doi
Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J. (2012)
Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.
Cell Death Differ. 19(5):798-807. doi: 10.1038/cdd.2011.150
Europe PMC | doi
Scolz M, Widlund PO, Piazza S, Bublik DR, Reber S, Peche LY, Ciani Y, Hubner N, Isokane M, Monte M, Ellenberg J, Hyman AA, Schneider C, Bird AW. (2012)
GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration
PLoS ONE 7(12):e51259. doi: 10.1371/journal.pone.0051259
Europe PMC | doi
2011
Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W. (2011)
Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases
Genome Res. 21(11):1955-1968. doi: 10.1101/gr.116087.110
Europe PMC | doi
Kitajima TS, Ohsugi M, Ellenberg J. (2011)
Complete kinetochore tracking reveals error-prone homologous chromosome biorientation in mammalian oocytes
Cell 146(4):568-581. doi: 10.1016/j.cell.2011.07.031
Europe PMC | doi
Ng K, Daigle N, Bancaud A, Ohhata T, Humphreys P, Walker R, Ellenberg J, Wutz A. (2011)
A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells
Mol. Biol. Cell 22(14):2634-2645. doi: 10.1091/mbc.e11-02-0146
Europe PMC | doi
Sironi L, Solon J, Conrad C, Mayer TU, Brunner D, Ellenberg J. (2011)
Automatic quantification of microtubule dynamics enables RNAi-screening of new mitotic spindle regulators
Cytoskeleton (Hoboken) 68(5):266-278. doi: 10.1002/cm.20510
Europe PMC | doi
Mori M, Monnier N, Daigle N, Bathe M, Ellenberg J, Lénárt P. (2011)
Intracellular transport by an anchored homogeneously contracting F-actin meshwork
Curr. Biol. 21(7):606-611. doi: 10.1016/j.cub.2011.03.002
Europe PMC | doi
Bolhy S, Bouhlel I, Dultz E, Nayak T, Zuccolo M, Gatti X, Vallee R, Ellenberg J, Doye V. (2011)
A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase
J. Cell Biol. 192(5):855-871. doi: 10.1083/jcb.201007118
Europe PMC | doi
Conrad C, Wünsche A, Tan TH, Bulkescher J, Sieckmann F, Verissimo F, Edelstein A, Walter T, Liebel U, Pepperkok R, Ellenberg J. (2011)
Micropilot: automation of fluorescence microscopy-based imaging for systems biology
Nat. Methods 8(3):246-249. doi: 10.1038/nmeth.1558
Europe PMC | doi
Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R. (2011)
The quantitative proteome of a human cell line
Mol. Syst. Biol. 7:549. doi: 10.1038/msb.2011.82
Europe PMC | doi
Mall M, Walter T, Gorjanacz M, Ellenberg J, Mattaj IW. (2011)
Mitotic Lamin disassembly is triggered by a lipid-mediated mitotic Lipin signaling pathway
MOL BIOL CELL 22
2010
Bancaud A, Huet S, Rabut G, Ellenberg J. (2010)
Fluorescence perturbation techniques to study mobility and molecular dynamics of proteins in live cells: FRAP, photoactivation, photoconversion, and FLIP
Cold Spring Harb Protoc 2010(12):pdb.top90. doi: 10.1101/pdb.top90
Europe PMC | doi
Landsverk HB, Mora-Bermúdez F, Landsverk OJ, Hasvold G, Naderi S, Bakke O, Ellenberg J, Collas P, Syljuåsen RG, Küntziger T. (2010)
The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response
EMBO Rep. 11(11):868-875. doi: 10.1038/embor.2010.134
Europe PMC | doi
Dultz E, Ellenberg J. (2010)
Live imaging of single nuclear pores reveals unique assembly kinetics and mechanism in interphase
J. Cell Biol. 191(1):15-22. doi: 10.1083/jcb.201007076
Europe PMC | doi
Held M, Schmitz MH, Fischer B, Walter T, Neumann B, Olma MH, Peter M, Ellenberg J, Gerlich DW. (2010)
CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.
Nat. Methods 7(9):747-754. doi: 10.1038/nmeth.1486
Europe PMC | doi
Terjung S, Walter T, Seitz A, Neumann B, Pepperkok R, Ellenberg J. (2010)
High-throughput microscopy using live mammalian cells.
Cold Spring Harb Protoc 2010(7):pdb.top84. doi: 10.1101/pdb.top84
Europe PMC | doi
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM. (2010)
Systematic analysis of human protein complexes identifies chromosome segregation proteins
Science 328(5978):593-599. doi: 10.1126/science.1181348
Europe PMC | doi
Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J. (2010)
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
Nature 464(7289):721-727. doi: 10.1038/nature08869
Europe PMC | doi
Walter T, Held M, Neumann B, Hériché JK, Conrad C, Pepperkok R, Ellenberg J. (2010)
Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging
J. Struct. Biol. 170(1):1-9. doi: 10.1016/j.jsb.2009.10.004
Europe PMC | doi
Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S, Ragan MA, Schneider JE, Tomancak P, Hériché JK. (2010)
Visualization of image data from cells to organisms
Nat. Methods 7(3 Suppl):S26-41. doi: 10.1038/nmeth.1431
Europe PMC | doi
Huet S, Avilov SV, Ferbitz L, Daigle N, Cusack S, Ellenberg J. (2010)
Nuclear import and assembly of influenza A virus RNA polymerase studied in live cells by fluorescence cross-correlation spectroscopy
J. Virol. 84(3):1254-1264. doi: 10.1128/jvi.01533-09
Europe PMC | doi
2009
Bancaud A, Huet S, Daigle N, Mozziconacci J, Beaudouin J, Ellenberg J. (2009)
Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin
EMBO J. 28(24):3785-3798. doi: 10.1038/emboj.2009.340
Europe PMC | doi
Harder N, Mora-Bermúdez F, Godinez WJ, Wünsche A, Eils R, Ellenberg J, Rohr K. (2009)
Automatic analysis of dividing cells in live cell movies to detect mitotic delays and correlate phenotypes in time
Genome Res. 19(11):2113-2124. doi: 10.1101/gr.092494.109
Europe PMC | doi
Dultz E, Huet S, Ellenberg J. (2009)
Formation of the nuclear envelope permeability barrier studied by sequential photoswitching and flux analysis
Biophys. J. 97(7):1891-1897. doi: 10.1016/j.bpj.2009.07.024
Europe PMC | doi
Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, Ellenberg J, Panier S, Durocher D, Bartek J, Lukas J, Lukas C. (2009)
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
Cell 136(3):435-446. doi: 10.1016/j.cell.2008.12.041
Europe PMC | doi
Keppler A, Ellenberg J. (2009)
Chromophore-assisted laser inactivation of alpha- and gamma-tubulin SNAP-tag fusion proteins inside living cells
ACS Chem. Biol. 4(2):127-138. doi: 10.1021/cb800298u
Europe PMC | doi
2008
Lu W, Gotzmann J, Sironi L, Jaeger VM, Schneider M, Lüke Y, Uhlén M, Szigyarto CA, Brachner A, Ellenberg J, Foisner R, Noegel AA, Karakesisoglou I. (2008)
Sun1 forms immobile macromolecular assemblies at the nuclear envelope
Biochim. Biophys. Acta 1783(12):2415-2426. doi: 10.1016/j.bbamcr.2008.09.001
Europe PMC | doi
Schuh M, Ellenberg J. (2008)
A new model for asymmetric spindle positioning in mouse oocytes
Curr. Biol. 18(24):1986-1992. doi: 10.1016/j.cub.2008.11.022
Europe PMC | doi
Erfle H, Neumann B, Rogers P, Bulkescher J, Ellenberg J, Pepperkok R. (2008)
Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates
J Biomol Screen 13(7):575-580. doi: 10.1177/1087057108320133
Europe PMC | doi
Antonin W, Ellenberg J, Dultz E. (2008)
Nuclear pore complex assembly through the cell cycle: regulation and membrane organization
FEBS Lett. 582(14):2004-2016. doi: 10.1016/j.febslet.2008.02.067
Europe PMC | doi
Tegha-Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, Held M, Rogers P, Hupfeld K, Ruppert T, Ellenberg J, Gruss OJ. (2008)
EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.
J. Cell. Sci. 121(Pt 10):1718-1726. doi: 10.1242/jcs.019174
Europe PMC | doi