EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
Biography
PhD 1998, Freie Universität Berlin.
Predoctoral and postdoctoral research at the National Institutes of Health (NIH), Bethesda.
Group leader at EMBL since 1999.
Head of Gene Expression Unit 2006-2010.
Head of Cell Biology and Biophysics Unit since 2010.
ERC Advanced Investigator since 2016.
Publications
Total: 156 publication(s)
2006
Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J. (2006)
High-throughput RNAi screening by time-lapse imaging of live human cells.
Nat. Methods 3(5):385-390. doi: 10.1038/nmeth876
Europe PMC | doi
Schuh M, Ellenberg J. (2006)
Nuclear actin: a lack of export allows formation of filaments
Curr. Biol. 16(9):R321-3. doi: 10.1016/j.cub.2006.03.081
Europe PMC | doi
Beaudouin J, Mora-Bermúdez F, Klee T, Daigle N, Ellenberg J. (2006)
Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins
Biophys. J. 90(6):1878-1894. doi: 10.1529/biophysj.105.071241
Europe PMC | doi
Gerlich D, Hirota T, Koch B, Peters JM, Ellenberg J. (2006)
Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells
Curr. Biol. 16(4):333-344. doi: 10.1016/j.cub.2005.12.040
Europe PMC | doi
Lénárt P, Ellenberg J. (2006)
Monitoring the permeability of the nuclear envelope during the cell cycle
Methods 38(1):17-24. doi: 10.1016/j.ymeth.2005.07.010
Europe PMC | doi
Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J. (2006)
Time-lapse microscopy-based genome wide RNAI screening in live human cells.
Paper presented at the 2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Arlington, VA (USA), 6-9 April 2006.I S Biomed Imaging 1:245-246. doi: 10.1109/ISBI.2006.1624898
doi
2005
Chusainow J, Ajuh PM, Trinkle-Mulcahy L, Sleeman JE, Ellenberg J, Lamond AI. (2005)
FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35
RNA 11(8):1201-1214. doi: 10.1261/rna.7277705
Europe PMC | doi
Lénárt P, Bacher CP, Daigle N, Hand AR, Eils R, Terasaki M, Ellenberg J. (2005)
A contractile nuclear actin network drives chromosome congression in oocytes
Nature 436(7052):812-818. doi: 10.1038/nature03810
Europe PMC | doi
Rabut G, Ellenberg, J. (2005)
Photobleaching techniques to study mobility and molecular dynamics of proteins in live cells: FRAP, iFRAP and FLIP
Cold Spring Harbor Press.Live Cell Imaging: A Laboratory Manual 101-127.
2004
Dechat T, Gajewski A, Korbei B, Gerlich D, Daigle N, Haraguchi T, Furukawa K, Ellenberg J, Foisner R. (2004)
LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly
J. Cell. Sci. 117(Pt 25):6117-6128. doi: 10.1242/jcs.01529
Europe PMC | doi
Hirota T, Gerlich D, Koch B, Ellenberg J, Peters JM. (2004)
Distinct functions of condensin I and II in mitotic chromosome assembly
J. Cell. Sci. 117(Pt 26):6435-6445. doi: 10.1242/jcs.01604
Europe PMC | doi
Rabut G, Doye V, Ellenberg J. (2004)
Mapping the dynamic organization of the nuclear pore complex inside single living cells
Nat. Cell Biol. 6(11):1114-1121. doi: 10.1038/ncb1184
Europe PMC | doi
Rabut G, Ellenberg J. (2004)
Automatic real-time three-dimensional cell tracking by fluorescence microscopy
J Microsc 216(Pt 2):131-137. doi: 10.1111/j.0022-2720.2004.01404.x
Europe PMC | doi
Bubulya PA, Prasanth KV, Deerinck TJ, Gerlich D, Beaudouin J, Ellisman MH, Ellenberg J, Spector DL. (2004)
Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei
J. Cell Biol. 167(1):51-63. doi: 10.1083/jcb.200404120
Europe PMC | doi
Sumara I, Giménez-Abián JF, Gerlich D, Hirota T, Kraft C, de la Torre C, Ellenberg J, Peters JM. (2004)
Roles of polo-like kinase 1 in the assembly of functional mitotic spindles
Curr. Biol. 14(19):1712-1722. doi: 10.1016/j.cub.2004.09.049
Europe PMC | doi
Leung AK, Gerlich D, Miller G, Lyon C, Lam YW, Lleres D, Daigle N, Zomerdijk J, Ellenberg J, Lamond AI. (2004)
Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells
J. Cell Biol. 166(6):787-800. doi: 10.1083/jcb.200405013
Europe PMC | doi
Giannone G, Rondé P, Gaire M, Beaudouin J, Haiech J, Ellenberg J, Takeda K. (2004)
Calcium rises locally trigger focal adhesion disassembly and enhance residency of focal adhesion kinase at focal adhesions
J. Biol. Chem. 279(27):28715-28723. doi: 10.1074/jbc.m404054200
Europe PMC | doi
Giménez-Abián JF, Sumara I, Hirota T, Hauf S, Gerlich D, de la Torre C, Ellenberg J, Peters JM. (2004)
Regulation of sister chromatid cohesion between chromosome arms
Curr. Biol. 14(13):1187-1193. doi: 10.1016/j.cub.2004.06.052
Europe PMC | doi
Loïodice I, Alves A, Rabut G, Van Overbeek M, Ellenberg J, Sibarita JB, Doye V. (2004)
The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis
Mol. Biol. Cell 15(7):3333-3344. doi: 10.1091/mbc.e03-12-0878
Europe PMC | doi
Conrad C, Erfle H, Warnat P, Daigle N, Lörch T, Ellenberg J, Pepperkok R, Eils R. (2004)
Automatic identification of subcellular phenotypes on human cell arrays
Genome Res. 14(6):1130-1136. doi: 10.1101/gr.2383804
Europe PMC | doi
Rabut G, Lénárt P, Ellenberg J. (2004)
Dynamics of nuclear pore complex organization through the cell cycle
Curr. Opin. Cell Biol. 16(3):314-321. doi: 10.1016/j.ceb.2004.04.001
Europe PMC | doi
Forler D, Rabut G, Ciccarelli FD, Herold A, Köcher T, Niggeweg R, Bork P, Ellenberg J, Izaurralde E. (2004)
RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export
Mol. Cell. Biol. 24(3):1155-1167. doi: 10.1128/mcb.24.3.1155-1167.2004
Europe PMC | doi
Strickland L, von Dassow G, Ellenberg J, Foe V, Lenart P, Burgess D. (2004)
Light microscopy of echinoderm embryos
Methods Cell Biol. 74:371-409. doi: 10.1016/S0091-679X(04)74016-9
Europe PMC | doi
2003
Gerlich D, Ellenberg J. (2003)
Dynamics of chromosome positioning during the cell cycle
Curr. Opin. Cell Biol. 15(6):664-671. doi: 10.1016/j.ceb.2003.10.014
Europe PMC | doi
Gerlich D, Ellenberg J. (2003)
4D imaging to assay complex dynamics in live specimens
Nat. Cell Biol. Suppl:S14-9.
Europe PMC
Raemaekers T, Ribbeck K, Beaudouin J, Annaert W, Van Camp M, Stockmans I, Smets N, Bouillon R, Ellenberg J, Carmeliet G. (2003)
NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization
J. Cell Biol. 162(6):1017-1029. doi: 10.1083/jcb.200302129
Europe PMC | doi
Gerlich D, Beaudouin J, Kalbfuss B, Daigle N, Eils R, Ellenberg J. (2003)
Global chromosome positions are transmitted through mitosis in mammalian cells
Cell 112(6):751-764. doi: 10.1016/s0092-8674(03)00189-2
Europe PMC | doi
Lénárt P, Rabut G, Daigle N, Hand AR, Terasaki M, Ellenberg J. (2003)
Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes
J. Cell Biol. 160(7):1055-1068. doi: 10.1083/jcb.200211076
Europe PMC | doi
Reid G, Hübner MR, Métivier R, Brand H, Denger S, Manu D, Beaudouin J, Ellenberg J, Gannon F. (2003)
Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling
Mol. Cell 11(3):695-707. doi: 10.1016/s1097-2765(03)00090-x
Europe PMC | doi
Lénárt P, Ellenberg J. (2003)
Nuclear envelope dynamics in oocytes: from germinal vesicle breakdown to mitosis
Curr. Opin. Cell Biol. 15(1):88-95. doi: 10.1016/s0955-0674(02)00011-x
Europe PMC | doi
2002
Hinkle B, Slepchenko B, Rolls MM, Walther TC, Stein PA, Mehlmann LM, Ellenberg J, Terasaki M. (2002)
Chromosomal association of Ran during meiotic and mitotic divisions
J. Cell. Sci. 115(Pt 23):4685-4693. doi: 10.1242/jcs.00136
Europe PMC | doi
Kruse C, Jaedicke A, Beaudouin J, Bohl F, Ferring D, Guttler T, Ellenberg J, Jansen RP. (2002)
Ribonucleoprotein-dependent localization of the yeast class V myosin Myo4p
J. Cell Biol. 159(6):971-982. doi: 10.1083/jcb.200207101
Europe PMC | doi
Burke B, Ellenberg J. (2002)
Remodelling the walls of the nucleus
Nat. Rev. Mol. Cell Biol. 3(7):487-497. doi: 10.1038/nrm860
Europe PMC | doi
Ellenberg J. (2002)
Dynamics of nuclear envelope proteins during the cell cycle in mammalian cells
Dynamics of Nuclear Envelope Assembly in Embryos and Somatic Cells 18-25.
Schmitt A, Gutierrez GJ, Lénárt P, Ellenberg J, Nebreda AR. (2002)
Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation
FEBS Lett. 518(1-3):23-28. doi: 10.1016/s0014-5793(02)02630-3
Europe PMC | doi
Beaudouin J, Gerlich D, Daigle N, Eils R, Ellenberg J. (2002)
Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina
Cell 108(1):83-96. doi: 10.1016/s0092-8674(01)00627-4
Europe PMC | doi
2001
Belgareh N, Rabut G, Baï SW, van Overbeek M, Beaudouin J, Daigle N, Zatsepina OV, Pasteau F, Labas V, Fromont-Racine M, Ellenberg J, Doye V. (2001)
An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells
J. Cell Biol. 154(6):1147-1160. doi: 10.1083/jcb.200101081
Europe PMC | doi
Gerlich D, Beaudouin J, Gebhard M, Ellenberg J, Eils R. (2001)
Four-dimensional imaging and quantitative reconstruction to analyse complex spatiotemporal processes in live cells
Nat. Cell Biol. 3(9):852-855. doi: 10.1038/ncb0901-852
Europe PMC | doi
Daigle N, Beaudouin J, Hartnell L, Imreh G, Hallberg E, Lippincott-Schwartz J, Ellenberg J. (2001)
Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells
J. Cell Biol. 154(1):71-84. doi: 10.1083/jcb.200101089
Europe PMC | doi
Rabut G, Ellenberg J. (2001)
Nucleocytoplasmic transport: diffusion channel or phase transition?
Curr. Biol. 11(14):R551-4. doi: 10.1016/s0960-9822(01)00340-2
Europe PMC | doi
Terasaki M, Campagnola P, Rolls MM, Stein PA, Ellenberg J, Hinkle B, Slepchenko B. (2001)
A new model for nuclear envelope breakdown
Mol. Biol. Cell 12(2):503-510. doi: 10.1091/mbc.12.2.503
Europe PMC | doi
2000
Dey A, Ellenberg J, Farina A, Coleman AE, Maruyama T, Sciortino S, Lippincott-Schwartz J, Ozato K. (2000)
A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition
Mol. Cell. Biol. 20(17):6537-6549. doi: 10.1128/mcb.20.17.6537-6549.2000
Europe PMC | doi
Nehls S, Snapp EL, Cole NB, Zaal KJ, Kenworthy AK, Roberts TH, Ellenberg J, Presley JF, Siggia E, Lippincott-Schwartz J. (2000)
Dynamics and retention of misfolded proteins in native ER membranes
Nat. Cell Biol. 2(5):288-295. doi: 10.1038/35010558
Europe PMC | doi
1999
Zaal KJ, Smith CL, Polishchuk RS, Altan N, Cole NB, Ellenberg J, Hirschberg K, Presley JF, Roberts TH, Siggia E, Phair RD, Lippincott-Schwartz J. (1999)
Golgi membranes are absorbed into and reemerge from the ER during mitosis
Cell 99(6):589-601. doi: 10.1016/s0092-8674(00)81548-2
Europe PMC | doi
Ellenberg J, Lippincott-Schwartz J. (1999)
Dynamics and mobility of nuclear envelope proteins in interphase and mitotic cells revealed by green fluorescent protein chimeras
Methods 19(3):362-372. doi: 10.1006/meth.1999.0872
Europe PMC | doi
Ostlund C, Ellenberg J, Hallberg E, Lippincott-Schwartz J, Worman HJ. (1999)
Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein
J. Cell. Sci. 112 ( Pt 11)(11):1709-1719.
Europe PMC
Ellenberg J, Lippincott-Schwartz J, Presley JF. (1999)
Dual-colour imaging with GFP variants
Trends Cell Biol. 9(2):52-56. doi: 10.1016/s0962-8924(98)01420-2
Europe PMC | doi
Lippincott-Schwartz J, Presley JF, Zaal KJ, Hirschberg K, Miller CD, Ellenberg J. (1999)
Monitoring the dynamics and mobility of membrane proteins tagged with green fluorescent protein
Methods Cell Biol. 58:261-281.
Europe PMC
1998
Hirschberg K, Miller CM, Ellenberg J, Presley JF, Siggia ED, Phair RD, Lippincott-Schwartz J. (1998)
Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells
J. Cell Biol. 143(6):1485-1503. doi: 10.1083/jcb.143.6.1485
Europe PMC | doi
Ellenberg J, Lippincott-Schwartz J, Presley JF. (1998)
Two-color green fluorescent protein time-lapse imaging
BioTechniques 25(5):838-42, 844-6.
Europe PMC
Sloan-Lancaster J, Presley J, Ellenberg J, Yamazaki T, Lippincott-Schwartz J, Samelson LE. (1998)
ZAP-70 association with T cell receptor zeta (TCRzeta): fluorescence imaging of dynamic changes upon cellular stimulation
J. Cell Biol. 143(3):613-624. doi: 10.1083/jcb.143.3.613
Europe PMC | doi
Cole NB, Ellenberg J, Song J, DiEuliis D, Lippincott-Schwartz J. (1998)
Retrograde transport of Golgi-localized proteins to the ER
J. Cell Biol. 140(1):1-15. doi: 10.1083/jcb.140.1.1
Europe PMC | doi
1997
Ellenberg J, Siggia ED, Moreira JE, Smith CL, Presley JF, Worman HJ, Lippincott-Schwartz J. (1997)
Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis
J. Cell Biol. 138(6):1193-1206. doi: 10.1083/jcb.138.6.1193
Europe PMC | doi
Ellenberg J, Lippincott-Schwartz J. (1997)
Fluorescence photobleaching techniques
Cold Spring Harbor Laboratory Press, Cold Spring Harbor.Cells: A Laboratory Manual 2(79):1-23.
Yang M, Ellenberg J, Bonifacino JS, Weissman AM. (1997)
The transmembrane domain of a carboxyl-terminal anchored protein determines localization to the endoplasmic reticulum
J. Biol. Chem. 272(3):1970-1975. doi: 10.1074/jbc.272.37.23000
Europe PMC | doi
1995
Müller-Röber B, Ellenberg J, Provart N, Willmitzer L, Busch H, Becker D, Dietrich P, Hoth S, Hedrich R. (1995)
Cloning and electrophysiological analysis of KST1, an inward rectifying K+ channel expressed in potato guard cells.
EMBO J. 14(11):2409-2416.
Europe PMC