EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Phone: +49 6221 387-8503


Total: 17 publication(s)


Heriche JK, Alexander S, Ellenberg J. (2019)

Integrating imaging and omics: computational methods and challenges.

Annu Rev Biomed Data Sci 2:175-197. doi: 10.1146/annurev-biodatasci-080917-013328


Cai Y, Hossain MJ, Hériché JK, Politi AZ, Walther N, Koch B, Wachsmuth M, Nijmeijer B, Kueblbeck M, Martinic-Kavur M, Ladurner R, Alexander S, Peters JM, Ellenberg J. (2018)

Experimental and computational framework for a dynamic protein atlas of human cell division.

Nature 561(7723) doi: 10.1038/s41586-018-0518-z
Europe PMC | doi

Dondossola E, Alexander S, Holzapfel BM, Filippini S, Starbuck MW, Hoffman RM, Navone N, De-Juan-Pardo EM, Logothetis CJ, Hutmacher DW, Friedl P. (2018)

Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone

SCI TRANSL MED 10(452) doi: 10.1126/scitranslmed.aao5726
Europe PMC | doi

Xiang W, Roberti MJ, Hériché JK, Huet S, Alexander S, Ellenberg J. (2018)

Correction: Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.

J Cell Biol 217(9):3315-3316. doi: 10.1083/JCB.20170907408082018c
Europe PMC | doi

Xiang W, Roberti MJ, Hériché JK, Huet S, Alexander S, Ellenberg J. (2018)

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.

J Cell Biol 217(6) doi: 10.1083/jcb.201709074
Europe PMC | doi

Barton C, Morganella S, Ødegård-Fougner Ø, Alexander S, Ries J, Fitzgerald T, Ellenberg J, Birney E. (2018)

ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy.

PLoS Comput Biol 14(3) doi: 10.1371/journal.pcbi.1006002
Europe PMC | doi


Dondossola E, Holzapfel BM, Alexander S, Filippini S, Hutmacher DW, Friedl P. (2016)

Examination of the foreign body response to biomaterials by nonlinear intravital microscopy

Nat Biomed Eng 1 doi: doi:10.1038/s41551-016-0007


Chatterji T, Varkaris AS, Parikh NU, Song JH, Cheng CJ, Schweppe RE, Alexander S, Davis JW, Troncoso P, Friedl P, Kuang J, Lin SH, Gallick GE. (2015)

Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells.

Oncotarget 6(12):10175-101794. doi: 10.18632/oncotarget.3391
Europe PMC | doi


Alexander S, Weigelin B, Winkler F, Friedl P. (2013)

Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response

CURR OPIN CELL BIOL 25(5):659-671. doi: 10.1016/j.ceb.2013.07.001
Europe PMC | doi

Wolf K, te Lindert M, Krause M, Alexander S, te Riet J, Willis AL, Hoffman RM, Figdor CG, Weiss SJ, Friedl P. (2013)

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

J CELL BIOL 201(7):1069-1084. doi: 10.1083/jcb.201210152
Europe PMC | doi

Häger A, Alexander S, Friedl P. (2013)

Cancer invasion and resistance

EJC Suppl 11(2):291-293. doi: 10.1016/j.ejcsup.2013.07.055


Alexander S, Friedl P. (2012)

Cancer invasion and resistance: interconnected processes of disease progression and therapy failure

TRENDS MOL MED 18(1):13-26. doi: 10.1016/j.molmed.2011.11.003
Europe PMC | doi


Friedl P, Alexander S. (2011)

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

CELL 147(5):992-1009. doi: 10.1016/j.cell.2011.11.016
Europe PMC | doi


Wolf K, Alexander S, Schacht V, Coussens LM, von Andrian UH, van Rheenen J, Deryugina E, Friedl P. (2009)

Collagen-based cell migration models in vitro and in vivo

SEMIN CELL DEV BIOL 20(8):931-941. doi: 10.1016/j.semcdb.2009.08.005
Europe PMC | doi

Imle A, Polzer B, Alexander S, Klein CA, Friedl P. (2009)

Genomic instability of micronucleated cells revealed by single-cell comparative genomic hybridization.

Cytometry A 75(7):562-568. doi: 10.1002/cyto.a.20733
Europe PMC | doi

Andresen V, Alexander S, Heupel WM, Hirschberg M, Hoffman RM, Friedl P. (2009)

Infrared multiphoton microscopy: subcellular-resolved deep tissue imaging

CURR OPIN BIOTECH 20(1):54-62. doi: 10.1016/j.copbio.2009.02.008
Europe PMC | doi


Alexander S, Koehl GE, Hirschberg M, Geissler EK, Friedl P. (2008)

Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model

HISTOCHEM CELL BIOL 130(6):1147-1154. doi: 10.1007/s00418-008-0529-1
Europe PMC | doi