Guerra M, Frey D, Hagner M, Dittrich S, Paulsen M, Mall MA, Schultz C. (2019)

Cathepsin G Activity as a New Marker for Detecting Airway Inflammation by Microscopy and Flow Cytometry.

ACS Cent Sci 5(3):539-548. doi: 10.1021/acscentsci.8b00933
Europe PMC | doi

Hauke S, Dutta AK, Eisenbeis VB, Bezold D, Bittner T, Wittwer C, Thakor D, Pavlovic I, Schultz C, Jessen HJ. (2019)

Photolysis of cell-permeant caged inositol pyrophosphates controls oscillations of cytosolic calcium in a β-cell line.

Chem Sci 10(9):2687-2692. doi: 10.1039/c8sc03479f
Europe PMC | doi

Baser A, Skabkin M, Kleber S, Dang Y, Gülcüler Balta GS, Kalamakis G, Göpferich M, Ibañez DC, Schefzik R, Lopez AS, Bobadilla EL, Schultz C, Fischer B, Martin-Villalba A. (2019)

Onset of differentiation is post-transcriptionally controlled in adult neural stem cells.

Nature 566(7742) doi: 10.1038/s41586-019-0888-x
Europe PMC | doi

Frank JA, Broichhagen J, Yushchenko DA, Trauner D, Schultz C, Hodson DJ. (2018)

Optical tools for understanding the complexity of β-cell signalling and insulin release.

Nat Rev Endocrinol 14(12):721-737. doi: 10.1038/s41574-018-0105-2
Europe PMC | doi

Kirby IT, Kojic A, Arnold MR, Thorsell AG, Karlberg T, Vermehren-Schmaedick A, Sreenivasan R, Schultz C, Schüler H, Cohen MS. (2018)

A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity.

Cell Chem Biol doi: 10.1016/j.chembiol.2018.09.011
Europe PMC | doi

Hauke S, Keutler K, Phapale P, Yushchenko DA, Schultz C. (2018)

Endogenous Fatty Acids are Essential Signaling Factors of Pancreatic β-Cells and Insulin Secretion.

Diabetes doi: 10.2337/db17-1215
Europe PMC | doi

Yu X, Akbarzadeh R, Pieper M, Scholzen T, Gehrig S, Schultz C, Zillikens D, König P, Petersen F. (2018)

Neutrophil adhesion is a prerequisite for antibody-mediated proteolytic tissue damage in experimental epidermolysis bullosa acquisita.

J Invest Dermatol doi: 10.1016/j.jid.2018.03.1499
Europe PMC | doi

Hoffmann JE, Dziuba D, Stein F, Schultz C. (2018)

A Bifunctional Noncanonical Amino Acid: Synthesis, Expression, and Residue-Specific Proteome-wide Incorporation.

Biochemistry 57(31) doi: 10.1021/acs.biochem.8b00397
Europe PMC | doi

Laguerre A, Schultz C. (2018)

Novel lipid tools and probes for biological investigations.

Curr. Opin. Cell Biol. 53:97-104. doi: 10.1016/j.ceb.2018.06.013
Europe PMC | doi

Kath C, Goni-Oliver P, Müller R, Schultz C, Haucke V, Eickholt B, Schmoranzer J. (2018)

PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules.

PLoS One 13(4) doi: 10.1371/journal.pone.0193257
Europe PMC | doi

Dittrich AS, Kühbandner I, Gehrig S, Rickert-Zacharias V, Twigg M, Wege S, Taggart CC, Herth F, Schultz C, Mall MA. (2018)

Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis.

Eur Respir J 51(3) doi: 10.1183/13993003.01910-2017
Europe PMC | doi

Walter AM, Müller R, Tawfik B, Wierda KD, Pinheiro PS, Nadler A, McCarthy AW, Ziomkiewicz I, Kruse M, Reither G, Rettig J, Lehmann M, Haucke V, Hille B, Schultz C, Sorensen JB. (2017)

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis.

Elife 6 doi: 10.7554/eLife.30203
Europe PMC | doi

Frank JA, Yushchenko DA, Fine NHF, Duca M, Citir M, Broichhagen J, Hodson DJ, Schultz C, Trauner D. (2017)

Optical control of GPR40 signalling in pancreatic beta-cells

CHEM SCI 8(11):7604-7610. doi: 10.1039/c7sc01475a
Europe PMC | doi

Bogdanova YA, Schultz C, Belousov VV. (2017)

Local Generation and Imaging of Hydrogen Peroxide in Living Cells.

Curr Protoc Chem Biol 9(2):117-127. doi: 10.1002/cpch.20
Europe PMC | doi

Marat AL, Wallroth A, Lo WT, Müller R, Norata GD, Falasca M, Schultz C, Haucke V. (2017)

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate.

Science 356(6341):968-972. doi: 10.1126/science.aaf8310
Europe PMC | doi

Mücksch F, Laketa V, Müller B, Schultz C, Kräusslich HG. (2017)

Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring.

Elife 6 doi: 10.7554/eLife.25287
Europe PMC | doi

Zuidscherwoude M, Dunlock VE, van den Bogaart G, van Deventer SJ, van der Schaaf A, van Oostrum J, Goedhart J, In 't Hout J, Hämmerling GJ, Tanaka S, Nadler A, Schultz C, Wright MD, Adjobo-Hermans MJW, van Spriel AB. (2017)

Tetraspanin microdomains control localized protein kinase C signaling in B cells.

Sci Signal 10(478):1-15. doi: 10.1126/scisignal.aag2755
Europe PMC | doi

Schifferer M, Yushchenko DA, Stein F, Bolbat A, Schultz C. (2017)

A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells.

Cell Chem Biol 24(4):525-531. doi: 10.1016/j.chembiol.2017.03.001
Europe PMC | doi

Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A. (2017)

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Dev. Cell 40(4):331-341. doi: 10.1016/j.devcel.2017.01.015
Europe PMC | doi

Höglinger D, Nadler A, Haberkant P, Kirkpatrick J, Schifferer M, Stein F, Hauke S, Porter FD, Schultz C. (2017)

Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.

Proc. Natl. Acad. Sci. U.S.A. 114(7):1566-1571. doi: 10.1073/pnas.1611096114
Europe PMC | doi

Taggart C, Mall MA, Lalmanach G, Cataldo D, Ludwig A, Janciauskiene S, Heath N, Meiners S, Overall CM, Schultz C, Turk B, Borensztajn KS. (2017)

Protean proteases: at the cutting edge of lung diseases.

Eur. Respir. J. 49(2) doi: 10.1183/13993003.01200-2015
Europe PMC | doi

Papadopoulos T, Rhee HJ, Subramanian D, Paraskevopoulou F, Mueller R, Schultz C, Brose N, Rhee JS, Betz H. (2017)

Endosomal Phosphatidylinositol 3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses.

J. Biol. Chem. 292(4):1160-1177. doi: 10.1074/jbc.M116.771592
Europe PMC | doi

Schifferer M, Feng S, Stein F, Schultz C. (2017)

Reversible Chemical Dimerization by rCD1.

Meth. Enzymol. 583:173-195. doi: 10.1016/bs.mie.2016.10.035
Europe PMC | doi

Kuchenov D, Laketa V, Stein F, Salopiata F, Klingmüller U, Schultz C. (2016)

High-Content Imaging Platform for Profiling Intracellular Signaling Network Activity in Living Cells.

Cell Chem Biol 23(12):1550-1559. doi: 10.1016/j.chembiol.2016.11.008
Europe PMC | doi

Wagner CJ, Schultz C, Mall MA. (2016)

Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease.

Mol Cell Pediatr 3(1) doi: 10.1186/s40348-016-0053-7
Europe PMC | doi

Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, Landry JJ, Fritz MH, Radic K, Hoffmann JE, Chen ZA, Zou J, Tan PS, Galik B, Junttila S, Stolt-Bergner P, Pruneri G, Gyenesei A, Schultz C, Biskup MB, Besir H, Benes V, Rappsilber J, Jechlinger M, Korbel JO, Berger I, Braese S, Lemke EA. (2016)

Genetic code expansion for multiprotein complex engineering.

Nat. Methods 13(12) doi: 10.1038/nmeth.4032
Europe PMC | doi

Bolbat A, Schultz C. (2016)

Recent developments of genetically encoded optical sensors for cell biology.

Biol. Cell 109(1) doi: 10.1111/boc.201600040
Europe PMC | doi

Rickert-Zacharias V, Schultz C, Mall MA. (2016)

A Protease Inhibitor Tackles Epithelial Sodium Channels in Cystic Fibrosis.

Am. J. Respir. Crit. Care Med. 194(6):650-652. doi: 10.1164/rccm.201604-0781ed
Europe PMC | doi

Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee JS, Gottschalk A, Brose N, Schultz C, Trauner D. (2016)

Photoswitchable diacylglycerols enable optical control of protein kinase C.

Nat. Chem. Biol. 12(9):755-762. doi: 10.1038/nchembio.2141
Europe PMC | doi

Bilgin M, Born P, Fezza F, Heimes M, Mastrangelo N, Wagner N, Schultz C, Maccarrone M, Eaton S, Nadler A, Wilm M, Shevchenko A. (2016)

Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS.

Sci Rep 6:27920. doi: 10.1038/srep27920
Europe PMC | doi

Simon B, Huart A, Temmerman K, Vahokoski J, Mertens H, Komadina D, Hoffmann J, Yumerefendi H, Svergun D, Kursula P, Schultz C, McCarthy A, Hart D, Wilmanns M. (2016)

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

Structure 24(6):851-861. doi: 10.1016/j.str.2016.03.020
Europe PMC | doi

Hövelmann F, Kedziora KM, Nadler A, Müller R, Jalink K, Schultz C. (2016)

Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient.

Cell Chem Biol 23(5) doi: 10.1016/j.chembiol.2015.11.019
Europe PMC | doi

Gerl MJ, Bittl V, Kirchner S, Sachsenheimer T, Brunner HL, Lüchtenborg C, Özbalci C, Wiedemann H, Wegehingel S, Nickel W, Haberkant P, Schultz C, Krüger M, Brügger B. (2016)

Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.

PLoS ONE 11(4) doi: 10.1371/journal.pone.0153009
Europe PMC | doi

Yushchenko DA, Nadler A, Schultz C. (2016)

Manipulating cell signaling with subcellular spatial resolution

Cell Cycle 15(8):1023-1024. doi: 10.1080/15384101.2016.1157974
Europe PMC | doi

Samarin J, Laketa V, Malz M, Roessler S, Stein I, Horwitz E, Singer S, Dimou E, Cigliano A, Bissinger M, Falk CS, Chen X, Dooley S, Pikarsky E, Calvisi DF, Scultzh C, Schirmacher P, Breuhahn K. (2016)

PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells.

Hepatology 63(3):813-826. doi: 10.1002/hep.28357
Europe PMC | doi

Pavlovic I, Thakor DT, Vargas JR, McKinlay CJ, Hauke S, Anstaett P, Camuña RC, Bigler L, Gasser G, Schultz C, Wender PA, Jessen HJ. (2016)

Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo.

Nat Commun 7(10622) doi: 10.1038/ncomms10622
Europe PMC | doi

Ketel K, Krauss M, Nicot AS, Puchkov D, Wieffer M, Müller R, Subramanian D, Schultz C, Laporte J, Haucke V. (2016)

A phosphoinositide conversion mechanism for exit from endosomes.

Nature 529(7586):408-12. doi: 10.1038/nature16516
Europe PMC | doi

Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C. (2016)

Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions.

ACS Chem Biol 11(1):222-230. doi: 10.1021/acschembio.5b00810
Europe PMC | doi

Nadler A, Yushchenko DA, Müller R, Stein F, Feng S, Mulle C, Carta M, Schultz C. (2015)

Exclusive photorelease of signalling lipids at the plasma membrane.

Nat Commun 6 doi: 10.1038/ncomms10056
Europe PMC | doi

Hu HY, Lim NH, Juretschke HP, Ding-Pfennigdorff D, Florian P, Kohlmann M, Kandira A, von Kries JP, Saas J, Rudolphi KA, Wendt KU, Nagase H, Plettenburg O, Nazare M, Schultz C. (2015)

In vivo visualization of osteoarthritic hypertrophic lesions

Chem Sci 6(11):6256-6261. doi: 10.1039/c5sc01301a
Europe PMC | doi

Höglinger D, Haberkant P, Aguilera-Romero A, Riezman H, Porter FD, Platt FM, Galione A, Schultz C. (2015)

Intracellular sphingosine releases calcium from lysosomes.

Elife 4 doi: 10.7554/eLife.10616
Europe PMC | doi

Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. (2015)

Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling.

Chem-Eur J 21(35):12266-12270. doi: 10.1002/chem.201501647
Europe PMC | doi

Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. (2015)

Frontispiece: Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling.

Chemistry 21(35) doi: 10.1002/chem.201583561
Europe PMC | doi

MacNamara A, Stein F, Feng S, Schultz C, Saez-Rodriguez J. (2015)

A single-cell model of PIP3 dynamics using chemical dimerization.

Bioorg. Med. Chem. 23(12) doi: 10.1016/j.bmc.2015.04.074
Europe PMC | doi

Schifferer M, Feng S, Stein F, Tischer C, Schultz C. (2015)

Reversible chemical dimerizer-induced recovery of PIP2 levels moves clathrin to the plasma membrane.

Bioorg. Med. Chem. 23(12):2862-2867. doi: 10.1016/j.bmc.2015.03.048
Europe PMC | doi

Bertozzi CR, Stockwell BR, Kubicek S, Dickinson BC, Chang CJ, Schultz C, Silver PA, Gestwicki JE, Chiosis G, Chattopadhyay A, Butcher RA, Park SB, Shoichet BK, Flitsch SL, Zhang J, Liu DR, Ohnishi Y, Weerapana E, Williams AH, He C, Moroni A, Thiel G, Chang YT, Waldmann H, Bogyo M, Oddershede LB, Christopoulos A, Imperiali B, Ehrlich H, Chen X, Prescher JA. (2015)

Voices of chemical biology

Nat. Chem. Biol. 11(6):378-379. doi: 10.1038/nchembio.1820
Europe PMC | doi

Mishina NM, Mishin AS, Belyaev Y, Bogdanova EA, Lukyanov S, Schultz C, Belousov VV. (2015)

Live-Cell STED Microscopy with Genetically Encoded Biosensor

Nano Lett. 15(5):2928-2932. doi: 10.1021/nl504710z
Europe PMC | doi

Hu HY, Lim NH, Ding-Pfennigdorff D, Saas J, Wendt KU, Ritzeler O, Nagase H, Plettenburg O, Schultz C, Nazare M. (2015)

DOTAM Derivatives as Active Cartilage-Targeting Drug Carriers for the Treatment of Osteoarthritis

Bioconjugate Chem. 26(3):383-388. doi: 10.1021/bc500557s
Europe PMC | doi

Trojanek JB, Cobos-Correa A, Diemer S, Kormann M, Schubert SC, Zhou-Suckow Z, Agrawal R, Duerr J, Wagner CJ, Schatterny J, Hirtz S, Sommerburg O, Hartl D, Schultz C, Mall MA. (2014)

Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema

Am. J. Respir. Cell Mol. Biol. 51(5):709-720. doi: 10.1165/rcmb.2013-0407oc
Europe PMC | doi

Rutkowska A, Plass T, Hoffmann JE, Yushchenko DA, Feng S, Schultz C. (2014)

T-CrAsH: A Heterologous Chemical Crosslinker

Chembiochem 15(12):1765-1768. doi: 10.1002/cbic.201402189
Europe PMC | doi

Höglinger D, Nadler A, Schultz C. (2014)

Caged lipids as tools for investigating cellular signaling

Biochim. Biophys. Acta 1841(8):1085-1096. doi: 10.1016/j.bbalip.2014.03.012
Europe PMC | doi

Schultz C. (2014)

The European Molecular Biology Laboratory (EMBL) - Its Anniversary and Its Chemistry.

Angew. Chem. Int. Ed. Engl. 53(30):7680-7681. doi: 10.1002/anie.201405106
Europe PMC | doi

Mall MA, Schultz C. (2014)

A New Player in the Game: Epithelial Cathepsin S in Early Cystic Fibrosis Lung Disease

Am. J. Resp. Crit. Care 190(2):126-127. doi: 10.1164/rccm.201405-0935ED
Europe PMC | doi

Hu HY, Vats D, Vizovisek M, Kramer L, Germanier C, Wendt KU, Rudin M, Turk B, Plettenburg O, Schultz C. (2014)

In Vivo Imaging of Mouse Tumors by a Lipidated Cathepsin S Substrate

Angew. Chem. Int. Ed. Engl. 53(29):7669-7673. doi: 10.1002/anie.201310979
Europe PMC | doi

Feng S, Laketa V, Stein F, Rutkowska A, MacNamara A, Depner S, Klingmüller U, Saez-Rodriguez J, Schultz C. (2014)

A rapidly reversible chemical dimerizer system to study lipid signaling in living cells

Angew. Chem. Int. Ed. Engl. 53(26):6720-6723. doi: 10.1002/anie.201402294
Europe PMC | doi

Reversi A, Loeser E, Subramanian D, Schultz C, De Renzis S. (2014)

Plasma membrane phosphoinositide balance regulates cell shape during Drosophila embryo morphogenesis

J. Cell Biol. 205(3):395-408. doi: 10.1083/jcb.201309079
Europe PMC | doi

Gehrig S, Duerr J, Weitnauer M, Wagner CJ, Graeber SY, Schatterny J, Hirtz S, Belaaouaj A, Dalpke AH, Schultz C, Mall MA. (2014)

Lack of neutrophil elastase reduces inflammation, mucus hypersecretion and emphysema, but not mucus obstruction, in mice with CF-like lung disease

Am. J. Respir. Crit. Care Med. 189(9):1082-1092. doi: 10.1164/rccm.201311-1932oc
Europe PMC | doi

Bilan DS, Matlashov ME, Gorokhovatsky AY, Schultz C, Enikolopov G, Belousov VV. (2014)

Genetically encoded fluorescent indicator for imaging NAD(+)/NADH ratio changes in different cellular compartments

Biochim. Biophys. Acta 1840(3):951-957. doi: 10.1016/j.bbagen.2013.11.018
Europe PMC | doi

Carta M, Lanore F, Rebola N, Szabo Z, Da Silva SV, Lourenço J, Verraes A, Nadler A, Schultz C, Blanchet C, Mulle C. (2014)

Membrane lipids tune synaptic transmission by direct modulation of presynaptic potassium channels

Neuron 81(4):787-799. doi: 10.1016/j.neuron.2013.12.028
Europe PMC | doi

Nikić I, Plass T, Schraidt O, Szymański J, Briggs JA, Schultz C, Lemke EA. (2014)

Minimal Tags for Rapid Dual-Color Live-Cell Labeling and Super-Resolution Microscopy

Angew. Chem. Int. Ed. Engl. 53(8):2245-2249. doi: 10.1002/anie.201309847
Europe PMC | doi

Hu HY, Gehrig S, Reither G, Subramanian D, Mall MA, Plettenburg O, Schultz C. (2014)

FRET-based and other fluorescent proteinase probes

Biotechnol J 9(2):266-281. doi: 10.1002/biot.201300201
Europe PMC | doi

Laketa V, Zarbakhsh S, Traynor-Kaplan A, Macnamara A, Subramanian D, Putyrski M, Mueller R, Nadler A, Mentel M, Saez-Rodriguez J, Pepperkok R, Schultz C. (2014)

PIP₃ induces the recycling of receptor tyrosine kinases

Sci Signal 7(308):ra5. doi: 10.1126/scisignal.2004532
Europe PMC | doi

Yushchenko DA, Schultz C. (2013)

Tissue clearing for optical anatomy

Angew. Chem. Int. Ed. Engl. 52(42):10949-10951. doi: 10.1002/anie.201306039
Europe PMC | doi

Reither G, Chatterjee J, Beullens M, Bollen M, Schultz C, Köhn M. (2013)

Chemical activators of protein phosphatase-1 induce calcium release inside intact cells

Chem. Biol. 20(9):1179-1186. doi: 10.1016/j.chembiol.2013.07.008
Europe PMC | doi

Stein F, Kress M, Reither S, Piljić A, Schultz C. (2013)

FluoQ: a tool for rapid analysis of multiparameter fluorescence imaging data applied to oscillatory events

ACS Chem. Biol. 8(9):1862-1868. doi: 10.1021/cb4003442
Europe PMC | doi

Posor Y, Eichhorn-Gruenig M, Puchkov D, Schöneberg J, Ullrich A, Lampe A, Müller R, Zarbakhsh S, Gulluni F, Hirsch E, Krauss M, Schultz C, Schmoranzer J, Noé F, Haucke V. (2013)

Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate

Nature 499(7457):233-237. doi: 10.1038/nature12360
Europe PMC | doi

Nadler A, Reither G, Feng S, Stein F, Reither S, Müller R, Schultz C. (2013)

The fatty acid composition of diacylglycerols determines local signaling patterns

Angew. Chem. Int. Ed. Engl. 52(24):6330-6334. doi: 10.1002/anie.201301716
Europe PMC | doi

Haberkant P, Raijmakers R, Wildwater M, Sachsenheimer T, Brügger B, Maeda K, Houweling M, Gavin AC, Schultz C, van Meer G, Heck AJ, Holthuis JC. (2013)

In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids

Angew. Chem. Int. Ed. Engl. 52(14):4033-4038. doi: 10.1002/anie.201210178
Europe PMC | doi

Bilan DS, Pase L, Joosen L, Gorokhovatsky AY, Ermakova YG, Gadella TW, Grabher C, Schultz C, Lukyanov S, Belousov VV. (2013)

HyPer-3: a genetically encoded H(2)O(2) probe with improved performance for ratiometric and fluorescence lifetime imaging

ACS Chem. Biol. 8(3):535-542. doi: 10.1021/cb300625g
Europe PMC | doi

Lukinavičius G, Umezawa K, Olivier N, Honigmann A, Yang G, Plass T, Mueller V, Reymond L, Corrêa IR Jr, Luo ZG, Schultz C, Lemke EA, Heppenstall P, Eggeling C, Manley S, Johnsson K. (2013)

A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

Nat Chem 5(2):132-139. doi: 10.1038/nchem.1546
Europe PMC | doi

Nadler A, Schultz C. (2013)

The power of fluorogenic probes

Angew. Chem. Int. Ed. Engl. 52(9):2408-2410. doi: 10.1002/anie.201209733
Europe PMC | doi

Milles S, Tyagi S, Plass T, Koehler C, Schultz C, Lemke EA. (2013)

Labeling Freedom for the Single Molecule Microscopist

BIOPHYS J 104(2):576A. doi: 10.1016/j.bpj.2012.11.3197
doi

Adjobo-Hermans MJ, Crosby KC, Putyrski M, Bhageloe A, van Weeren L, Schultz C, Goedhart J, Gadella TW Jr. (2013)

PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq

Cell. Signal. 25(1):255-263. doi: 10.1016/j.cellsig.2012.09.022
Europe PMC | doi

Mishina NM, Markvicheva KN, Bilan DS, Matlashov ME, Shirmanova MV, Liebl D, Schultz C, Lukyanov S, Belousov VV. (2013)

Visualization of intracellular hydrogen peroxide with HyPer, a genetically encoded fluorescent probe

Meth. Enzymol. 526:45-59. doi: 10.1016/b978-0-12-405883-5.00003-x
Europe PMC | doi

Mishina NM, Markvicheva KN, Fradkov AF, Zagaynova EV, Schultz C, Lukyanov S, Belousov VV. (2013)

Imaging H2O2 microdomains in receptor tyrosine kinases signaling

Meth. Enzymol. 526:175-187. doi: 10.1016/b978-0-12-405883-5.00011-9
Europe PMC | doi

Borrmann A, Milles S, Plass T, Dommerholt J, Verkade JM, Wiessler M, Schultz C, van Hest JC, van Delft FL, Lemke EA. (2012)

Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation

Chembiochem 13(14):2094-2099. doi: 10.1002/cbic.201200407
Europe PMC | doi

Wymann MP, Schultz C. (2012)

The chemical biology of phosphoinositide 3-kinases

Chembiochem 13(14):2022-2035. doi: 10.1002/cbic.201200089
Europe PMC | doi

Mishina NM, Bogeski I, Bolotin DA, Hoth M, Niemeyer BA, Schultz C, Zagaynova EV, Lukyanov S, Belousov VV. (2012)

Can we see PIP(3) and hydrogen peroxide with a single probe?

Antioxid. Redox Signal. 17(3):505-512. doi: 10.1089/ars.2012.4574
Europe PMC | doi

Rutkowska A, Schultz C. (2012)

Protein tango: the toolbox to capture interacting partners

Angew. Chem. Int. Ed. Engl. 51(33):8166-8176. doi: 10.1002/anie.201201717
Europe PMC | doi

Mundhenk L, Johannesson B, Anagnostopoulou P, Braun J, Bothe MK, Schultz C, Mall MA, Gruber AD. (2012)

mCLCA3 does not contribute to calcium-activated chloride conductance in murine airways

Am. J. Respir. Cell Mol. Biol. 47(1):87-93. doi: 10.1165/rcmb.2010-0508oc
Europe PMC | doi

Putyrski M, Schultz C. (2012)

Protein translocation as a tool: The current rapamycin story

FEBS Lett. 586(15):2097-2105. doi: 10.1016/j.febslet.2012.04.061
Europe PMC | doi

Gehrig S, Mall MA, Schultz C. (2012)

Spatially resolved monitoring of neutrophil elastase activity with ratiometric fluorescent reporters

Angew. Chem. Int. Ed. Engl. 51(25):6258-6261. doi: 10.1002/anie.201109226
Europe PMC | doi

Mertens HD, Piljić A, Schultz C, Svergun DI. (2012)

Conformational analysis of a genetically encoded FRET biosensor by SAXS

Biophys. J. 102(12):2866-2875. doi: 10.1016/j.bpj.2012.05.009
Europe PMC | doi

Plass T, Milles S, Koehler C, Szymański J, Mueller R, Wiessler M, Schultz C, Lemke EA. (2012)

Amino acids for Diels-Alder reactions in living cells

Angew. Chem. Int. Ed. Engl. 51(17):4166-4170. doi: 10.1002/anie.201108231
Europe PMC | doi

Plass T, Milles S, Koehler C, Schultz C, Lemke EA. (2012)

Labeling Freedom for the Single Molecule Microscopist

Biophys J 102(3 Suppl 1):217A. doi: 10.1016/j.bpj.2011.11.1187
doi

Cobos-Correa A, Stein F, Schultz C. (2012)

Target-Activated Prodrugs (TAPs) for the autoregulated inhibition of MMP12

ACS Med Chem Lett 3(8):653-657. doi: 10.1021/ml3001193
Europe PMC | doi

Johannesson B, Hirtz S, Schatterny J, Schultz C, Mall MA. (2012)

CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice

PLoS ONE 7(8):e44059. doi: 10.1371/journal.pone.0044059
Europe PMC | doi

Rutkowska A, Haering CH, Schultz C. (2011)

A FlAsH-based cross-linker to study protein interactions in living cells

Angew. Chem. Int. Ed. Engl. 50(52):12655-12658. doi: 10.1002/anie.201106404
Europe PMC | doi

Putyrski M, Schultz C. (2011)

Switching heterotrimeric G protein subunits with a chemical dimerizer

Chem. Biol. 18(9):1126-1133. doi: 10.1016/j.chembiol.2011.07.013
Europe PMC | doi

Lemke EA, Schultz C. (2011)

Principles for designing fluorescent sensors and reporters

Nat. Chem. Biol. 7(8):480-483. doi: 10.1038/nchembio.620
Europe PMC | doi

Piljić A, de Diego I, Wilmanns M, Schultz C. (2011)

Rapid development of genetically encoded FRET reporters

ACS Chem. Biol. 6(7):685-691. doi: 10.1021/cb100402n
Europe PMC | doi

Zhou Z, Duerr J, Johannesson B, Schubert SC, Treis D, Harm M, Graeber SY, Dalpke A, Schultz C, Mall MA. (2011)

The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease

J. Cyst. Fibros. 10 Suppl 2:S172-82. doi: 10.1016/s1569-1993(11)60021-0
Europe PMC | doi

Mentel M, Laketa V, Subramanian D, Gillandt H, Schultz C. (2011)

Photoactivatable and cell-membrane-permeable phosphatidylinositol 3,4,5-trisphosphate

Angew. Chem. Int. Ed. Engl. 50(16):3811-3814. doi: 10.1002/anie.201007796
Europe PMC | doi

Plass T, Milles S, Koehler C, Schultz C, Lemke EA. (2011)

Genetically encoded copper-free click chemistry

Angew. Chem. Int. Ed. Engl. 50(17):3878-3881. doi: 10.1002/anie.201008178
Europe PMC | doi

Schultz C, Aime S. (2011)

Imaging probes--Introduction

Bioorg. Med. Chem. 19(3):1022. doi: 10.1016/j.bmc.2011.01.040
Europe PMC | doi

Jackson SG, Al-Saigh S, Schultz C, Junop MS. (2011)

Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions

BMC Struct. Biol. 11:11. doi: 10.1186/1472-6807-11-11
Europe PMC | doi

Mishina NM, Tyurin-Kuzmin PA, Markvicheva KN, Vorotnikov AV, Tkachuk VA, Laketa V, Schultz C, Lukyanov S, Belousov VV. (2011)

Does cellular hydrogen peroxide diffuse or act locally?

Antioxid. Redox Signal. 14(1):1-7. doi: 10.1089/ars.2010.3539
Europe PMC | doi

Plass T, Schultz C. (2011)

Covalent labeling of biomolecules in living cells

In: Demchenko AP (ed.), Advanced Fluorescence Reporters in Chemistry and Biology III, vol 10. Springer Series on Fluorescence. Springer Berlin Heidelberg. pp 225-261.doi: 10.1007/978-3-642-18035-4_7
Europe PMC | doi

Mall MA, Button B, Johannesson B, Zhou Z, Livraghi A, Caldwell RA, Schubert SC, Schultz C, O'Neal WK, Pradervand S, Hummler E, Rossier BC, Grubb BR, Boucher RC. (2010)

Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice

J. Biol. Chem. 285(35):26945-26955. doi: 10.1074/jbc.m110.151803
Europe PMC | doi

Schultz C. (2010)

Challenges in studying phospholipid signaling

Nat. Chem. Biol. 6(7):473-475. doi: 10.1038/nchembio.389
Europe PMC | doi