Publications
Total: 133 publication(s)
2018
Kath C, Goni-Oliver P, Müller R, Schultz C, Haucke V, Eickholt B, Schmoranzer J. (2018)
PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules.
PLoS One 13(4) doi: 10.1371/journal.pone.0193257
Europe PMC | doi
Dittrich AS, Kühbandner I, Gehrig S, Rickert-Zacharias V, Twigg M, Wege S, Taggart CC, Herth F, Schultz C, Mall MA. (2018)
Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis.
Eur Respir J 51(3) doi: 10.1183/13993003.01910-2017
Europe PMC | doi
Yu X, Akbarzadeh R, Pieper M, Scholzen T, Gehrig S, Schultz C, Zillikens D, König P, Petersen F. (2018)
Neutrophil adhesion is a prerequisite for antibody-mediated proteolytic tissue damage in experimental epidermolysis bullosa acquisita.
J Invest Dermatol doi: 10.1016/j.jid.2018.03.1499
Europe PMC | doi
2017
Walter AM, Müller R, Tawfik B, Wierda KD, Pinheiro PS, Nadler A, McCarthy AW, Ziomkiewicz I, Kruse M, Reither G, Rettig J, Lehmann M, Haucke V, Hille B, Schultz C, Sorensen JB. (2017)
Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis.
Elife 6 doi: 10.7554/eLife.30203
Europe PMC | doi
Frank JA, Yushchenko DA, Fine NHF, Duca M, Citir M, Broichhagen J, Hodson DJ, Schultz C, Trauner D. (2017)
Optical control of GPR40 signalling in pancreatic beta-cells
CHEM SCI 8:7604-7610. doi: 10.1039/c7sc01475a
Europe PMC | doi
Bogdanova YA, Schultz C, Belousov VV. (2017)
Local Generation and Imaging of Hydrogen Peroxide in Living Cells.
Curr Protoc Chem Biol 9(2):117-127. doi: 10.1002/cpch.20
Europe PMC | doi
Marat AL, Wallroth A, Lo WT, Müller R, Norata GD, Falasca M, Schultz C, Haucke V. (2017)
mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate.
Science 356(6341):968-972. doi: 10.1126/science.aaf8310
Europe PMC | doi
Mücksch F, Laketa V, Müller B, Schultz C, Kräusslich HG. (2017)
Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring.
Elife 6 doi: 10.7554/eLife.25287
Europe PMC | doi
Zuidscherwoude M, Dunlock VE, van den Bogaart G, van Deventer SJ, van der Schaaf A, van Oostrum J, Goedhart J, In 't Hout J, Hämmerling GJ, Tanaka S, Nadler A, Schultz C, Wright MD, Adjobo-Hermans MJW, van Spriel AB. (2017)
Tetraspanin microdomains control localized protein kinase C signaling in B cells.
Sci Signal 10(478):1-15. doi: 10.1126/scisignal.aag2755
Europe PMC | doi
Schifferer M, Yushchenko DA, Stein F, Bolbat A, Schultz C. (2017)
A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells.
Cell Chem Biol 525-531. doi: 10.1016/j.chembiol.2017.03.001
Europe PMC | doi
Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A. (2017)
Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development
Dev. Cell 40(4):331-341. doi: 10.1016/j.devcel.2017.01.015
Europe PMC | doi
Höglinger D, Nadler A, Haberkant P, Kirkpatrick J, Schifferer M, Stein F, Hauke S, Porter FD, Schultz C. (2017)
Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.
Proc. Natl. Acad. Sci. U.S.A. 114(7):1566-1571. doi: 10.1073/pnas.1611096114
Europe PMC | doi
Taggart C, Mall MA, Lalmanach G, Cataldo D, Ludwig A, Janciauskiene S, Heath N, Meiners S, Overall CM, Schultz C, Turk B, Borensztajn KS. (2017)
Protean proteases: at the cutting edge of lung diseases.
Eur. Respir. J. 49(2) doi: 10.1183/13993003.01200-2015
Europe PMC | doi
Papadopoulos T, Rhee HJ, Subramanian D, Paraskevopoulou F, Mueller R, Schultz C, Brose N, Rhee JS, Betz H. (2017)
Endosomal Phosphatidylinositol 3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses.
J. Biol. Chem. 292(4):1160-1177. doi: 10.1074/jbc.M116.771592
Europe PMC | doi
Schifferer M, Feng S, Stein F, Schultz C. (2017)
Reversible Chemical Dimerization by rCD1.
Meth. Enzymol. 583:173-195. doi: 10.1016/bs.mie.2016.10.035
Europe PMC | doi
2016
Kuchenov D, Laketa V, Stein F, Salopiata F, Klingmüller U, Schultz C. (2016)
High-Content Imaging Platform for Profiling Intracellular Signaling Network Activity in Living Cells.
Cell Chem Biol 23(12):1550-1559. doi: 10.1016/j.chembiol.2016.11.008
Europe PMC | doi
Wagner CJ, Schultz C, Mall MA. (2016)
Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease.
Mol Cell Pediatr 3(1) doi: 10.1186/s40348-016-0053-7
Europe PMC | doi
Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, Landry JJ, Fritz MH, Radic K, Hoffmann JE, Chen ZA, Zou J, Tan PS, Galik B, Junttila S, Stolt-Bergner P, Pruneri G, Gyenesei A, Schultz C, Biskup MB, Besir H, Benes V, Rappsilber J, Jechlinger M, Korbel JO, Berger I, Braese S, Lemke EA. (2016)
Genetic code expansion for multiprotein complex engineering.
Nat. Methods doi: 10.1038/nmeth.4032
Europe PMC | doi
Bolbat A, Schultz C. (2016)
Recent developments of genetically encoded optical sensors for cell biology.
Biol. Cell doi: 10.1111/boc.201600040
Europe PMC | doi
Rickert-Zacharias V, Schultz C, Mall MA. (2016)
A Protease Inhibitor Tackles Epithelial Sodium Channels in Cystic Fibrosis.
Am. J. Respir. Crit. Care Med. 194(6):650-652. doi: 10.1164/rccm.201604-0781ed
Europe PMC | doi
Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee JS, Gottschalk A, Brose N, Schultz C, Trauner D. (2016)
Photoswitchable diacylglycerols enable optical control of protein kinase C.
Nat. Chem. Biol. 12(9):755-762. doi: 10.1038/nchembio.2141
Europe PMC | doi
Bilgin M, Born P, Fezza F, Heimes M, Mastrangelo N, Wagner N, Schultz C, Maccarrone M, Eaton S, Nadler A, Wilm M, Shevchenko A. (2016)
Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS.
Sci Rep 6:27920. doi: 10.1038/srep27920
Europe PMC | doi
Simon B, Huart A, Temmerman K, Vahokoski J, Mertens H, Komadina D, Hoffmann J, Yumerefendi H, Svergun D, Kursula P, Schultz C, McCarthy A, Hart D, Wilmanns M. (2016)
Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites
Structure 24(6):851-861. doi: 10.1016/j.str.2016.03.020
Europe PMC | doi
Hövelmann F, Kedziora KM, Nadler A, Müller R, Jalink K, Schultz C. (2016)
Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient.
Cell Chem Biol doi: 10.1016/j.chembiol.2015.11.019
Europe PMC | doi
Gerl MJ, Bittl V, Kirchner S, Sachsenheimer T, Brunner HL, Lüchtenborg C, Özbalci C, Wiedemann H, Wegehingel S, Nickel W, Haberkant P, Schultz C, Krüger M, Brügger B. (2016)
Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.
PLoS ONE 11(4) doi: 10.1371/journal.pone.0153009
Europe PMC | doi
Yushchenko DA, Nadler A, Schultz C. (2016)
Manipulating cell signaling with subcellular spatial resolution
Cell Cycle 15(8):1023-1024. doi: 10.1080/15384101.2016.1157974
Europe PMC | doi
Samarin J, Laketa V, Malz M, Roessler S, Stein I, Horwitz E, Singer S, Dimou E, Cigliano A, Bissinger M, Falk CS, Chen X, Dooley S, Pikarsky E, Calvisi DF, Scultzh C, Schirmacher P, Breuhahn K. (2016)
PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells.
Hepatology 63(3):813-826. doi: 10.1002/hep.28357
Europe PMC | doi
Pavlovic I, Thakor DT, Vargas JR, McKinlay CJ, Hauke S, Anstaett P, Camuña RC, Bigler L, Gasser G, Schultz C, Wender PA, Jessen HJ. (2016)
Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo.
Nat Commun 7(10622) doi: 10.1038/ncomms10622
Europe PMC | doi
Ketel K, Krauss M, Nicot AS, Puchkov D, Wieffer M, Müller R, Subramanian D, Schultz C, Laporte J, Haucke V. (2016)
A phosphoinositide conversion mechanism for exit from endosomes.
Nature 529(7586):408-12. doi: 10.1038/nature16516
Europe PMC | doi
Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C. (2016)
Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions.
ACS Chem Biol 11(1):222-230. doi: 10.1021/acschembio.5b00810
Europe PMC | doi
2015
Nadler A, Yushchenko DA, Müller R, Stein F, Feng S, Mulle C, Carta M, Schultz C. (2015)
Exclusive photorelease of signalling lipids at the plasma membrane.
Nat Commun 6 doi: 10.1038/ncomms10056
Europe PMC | doi
Hu HY, Lim NH, Juretschke HP, Ding-Pfennigdorff D, Florian P, Kohlmann M, Kandira A, von Kries JP, Saas J, Rudolphi KA, Wendt KU, Nagase H, Plettenburg O, Nazare M, Schultz C. (2015)
In vivo visualization of osteoarthritic hypertrophic lesions
Chem Sci 6:6256-6261. doi: 10.1039/c5sc01301a
doi
Höglinger D, Haberkant P, Aguilera-Romero A, Riezman H, Porter FD, Platt FM, Galione A, Schultz C. (2015)
Intracellular sphingosine releases calcium from lysosomes.
Elife 4 doi: 10.7554/eLife.10616
Europe PMC | doi
Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. (2015)
Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling.
Chem-Eur J 21(35):12266-12270. doi: 10.1002/chem.201501647
Europe PMC | doi
Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. (2015)
Frontispiece: Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling.
Chemistry 21(35) doi: 10.1002/chem.201583561
Europe PMC | doi
MacNamara A, Stein F, Feng S, Schultz C, Saez-Rodriguez J. (2015)
A single-cell model of PIP3 dynamics using chemical dimerization.
Bioorg. Med. Chem. doi: 10.1016/j.bmc.2015.04.074
Europe PMC | doi
Schifferer M, Feng S, Stein F, Tischer C, Schultz C. (2015)
Reversible chemical dimerizer-induced recovery of PIP2 levels moves clathrin to the plasma membrane.
Bioorg. Med. Chem. 23(12):2862-2867. doi: 10.1016/j.bmc.2015.03.048
Europe PMC | doi
Bertozzi CR, Stockwell BR, Kubicek S, Dickinson BC, Chang CJ, Schultz C, Silver PA, Gestwicki JE, Chiosis G, Chattopadhyay A, Butcher RA, Park SB, Shoichet BK, Flitsch SL, Zhang J, Liu DR, Ohnishi Y, Weerapana E, Williams AH, He C, Moroni A, Thiel G, Chang YT, Waldmann H, Bogyo M, Oddershede LB, Christopoulos A, Imperiali B, Ehrlich H, Chen X, Prescher JA. (2015)
Voices of chemical biology
Nat. Chem. Biol. 11(6):378-379. doi: 10.1038/nchembio.1820
Europe PMC | doi
Mishina NM, Mishin AS, Belyaev Y, Bogdanova EA, Lukyanov S, Schultz C, Belousov VV. (2015)
Live-Cell STED Microscopy with Genetically Encoded Biosensor
Nano Lett. 15(5):2928-2932. doi: 10.1021/nl504710z
Europe PMC | doi
Hu HY, Lim NH, Ding-Pfennigdorff D, Saas J, Wendt KU, Ritzeler O, Nagase H, Plettenburg O, Schultz C, Nazare M. (2015)
DOTAM Derivatives as Active Cartilage-Targeting Drug Carriers for the Treatment of Osteoarthritis
Bioconjugate Chem. 26(3):383-388. doi: 10.1021/bc500557s
Europe PMC | doi
2014
Trojanek JB, Cobos-Correa A, Diemer S, Kormann M, Schubert SC, Zhou-Suckow Z, Agrawal R, Duerr J, Wagner CJ, Schatterny J, Hirtz S, Sommerburg O, Hartl D, Schultz C, Mall MA. (2014)
Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema
Am. J. Respir. Cell Mol. Biol. 51(5):709-720. doi: 10.1165/rcmb.2013-0407oc
Europe PMC | doi
Rutkowska A, Plass T, Hoffmann JE, Yushchenko DA, Feng S, Schultz C. (2014)
T-CrAsH: A Heterologous Chemical Crosslinker
Chembiochem 15(12):1765-1768. doi: 10.1002/cbic.201402189
Europe PMC | doi
Höglinger D, Nadler A, Schultz C. (2014)
Caged lipids as tools for investigating cellular signaling
Biochim. Biophys. Acta 1841(8):1085-1096. doi: 10.1016/j.bbalip.2014.03.012
Europe PMC | doi
Schultz C. (2014)
The European Molecular Biology Laboratory (EMBL) - Its Anniversary and Its Chemistry.
Angew. Chem. Int. Ed. Engl. 53(30):7680-7681. doi: 10.1002/anie.201405106
Europe PMC | doi
Mall MA, Schultz C. (2014)
A New Player in the Game: Epithelial Cathepsin S in Early Cystic Fibrosis Lung Disease
Am. J. Resp. Crit. Care 190(2):126-127. doi: 10.1164/rccm.201405-0935ED
Europe PMC | doi
Hu HY, Vats D, Vizovisek M, Kramer L, Germanier C, Wendt KU, Rudin M, Turk B, Plettenburg O, Schultz C. (2014)
In Vivo Imaging of Mouse Tumors by a Lipidated Cathepsin S Substrate
Angew. Chem. Int. Ed. Engl. 53(29):7669-7673. doi: 10.1002/anie.201310979
Europe PMC | doi
Feng S, Laketa V, Stein F, Rutkowska A, MacNamara A, Depner S, Klingmüller U, Saez-Rodriguez J, Schultz C. (2014)
A rapidly reversible chemical dimerizer system to study lipid signaling in living cells
Angew. Chem. Int. Ed. Engl. 53(26):6720-6723. doi: 10.1002/anie.201402294
Europe PMC | doi
Reversi A, Loeser E, Subramanian D, Schultz C, De Renzis S. (2014)
Plasma membrane phosphoinositide balance regulates cell shape during Drosophila embryo morphogenesis
J. Cell Biol. 205(3):395-408. doi: 10.1083/jcb.201309079
Europe PMC | doi
Gehrig S, Duerr J, Weitnauer M, Wagner CJ, Graeber SY, Schatterny J, Hirtz S, Belaaouaj A, Dalpke AH, Schultz C, Mall MA. (2014)
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion and emphysema, but not mucus obstruction, in mice with CF-like lung disease
Am. J. Respir. Crit. Care Med. 189(9):1082-1092. doi: 10.1164/rccm.201311-1932oc
Europe PMC | doi
Bilan DS, Matlashov ME, Gorokhovatsky AY, Schultz C, Enikolopov G, Belousov VV. (2014)
Genetically encoded fluorescent indicator for imaging NAD(+)/NADH ratio changes in different cellular compartments
Biochim. Biophys. Acta 1840(3):951-957. doi: 10.1016/j.bbagen.2013.11.018
Europe PMC | doi
Carta M, Lanore F, Rebola N, Szabo Z, Da Silva SV, Lourenço J, Verraes A, Nadler A, Schultz C, Blanchet C, Mulle C. (2014)
Membrane lipids tune synaptic transmission by direct modulation of presynaptic potassium channels
Neuron 81(4):787-799. doi: 10.1016/j.neuron.2013.12.028
Europe PMC | doi
Nikić I, Plass T, Schraidt O, Szymański J, Briggs JA, Schultz C, Lemke EA. (2014)
Minimal Tags for Rapid Dual-Color Live-Cell Labeling and Super-Resolution Microscopy
Angew. Chem. Int. Ed. Engl. 53(8):2245-2249. doi: 10.1002/anie.201309847
Europe PMC | doi
Hu HY, Gehrig S, Reither G, Subramanian D, Mall MA, Plettenburg O, Schultz C. (2014)
FRET-based and other fluorescent proteinase probes
Biotechnol J 9(2):266-281. doi: 10.1002/biot.201300201
Europe PMC | doi
Laketa V, Zarbakhsh S, Traynor-Kaplan A, Macnamara A, Subramanian D, Putyrski M, Mueller R, Nadler A, Mentel M, Saez-Rodriguez J, Pepperkok R, Schultz C. (2014)
PIP₃ induces the recycling of receptor tyrosine kinases
Sci Signal 7(308):ra5. doi: 10.1126/scisignal.2004532
Europe PMC | doi
2013
Yushchenko DA, Schultz C. (2013)
Tissue clearing for optical anatomy
Angew. Chem. Int. Ed. Engl. 52(42):10949-10951. doi: 10.1002/anie.201306039
Europe PMC | doi
Reither G, Chatterjee J, Beullens M, Bollen M, Schultz C, Köhn M. (2013)
Chemical activators of protein phosphatase-1 induce calcium release inside intact cells
Chem. Biol. 20(9):1179-1186. doi: 10.1016/j.chembiol.2013.07.008
Europe PMC | doi
Stein F, Kress M, Reither S, Piljić A, Schultz C. (2013)
FluoQ: a tool for rapid analysis of multiparameter fluorescence imaging data applied to oscillatory events
ACS Chem. Biol. 8(9):1862-1868. doi: 10.1021/cb4003442
Europe PMC | doi
Posor Y, Eichhorn-Gruenig M, Puchkov D, Schöneberg J, Ullrich A, Lampe A, Müller R, Zarbakhsh S, Gulluni F, Hirsch E, Krauss M, Schultz C, Schmoranzer J, Noé F, Haucke V. (2013)
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate
Nature 499(7457):233-237. doi: 10.1038/nature12360
Europe PMC | doi
Nadler A, Reither G, Feng S, Stein F, Reither S, Müller R, Schultz C. (2013)
The fatty acid composition of diacylglycerols determines local signaling patterns
Angew. Chem. Int. Ed. Engl. 52(24):6330-6334. doi: 10.1002/anie.201301716
Europe PMC | doi
Haberkant P, Raijmakers R, Wildwater M, Sachsenheimer T, Brügger B, Maeda K, Houweling M, Gavin AC, Schultz C, van Meer G, Heck AJ, Holthuis JC. (2013)
In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids
Angew. Chem. Int. Ed. Engl. 52(14):4033-4038. doi: 10.1002/anie.201210178
Europe PMC | doi
Bilan DS, Pase L, Joosen L, Gorokhovatsky AY, Ermakova YG, Gadella TW, Grabher C, Schultz C, Lukyanov S, Belousov VV. (2013)
HyPer-3: a genetically encoded H(2)O(2) probe with improved performance for ratiometric and fluorescence lifetime imaging
ACS Chem. Biol. 8(3):535-542. doi: 10.1021/cb300625g
Europe PMC | doi
Lukinavičius G, Umezawa K, Olivier N, Honigmann A, Yang G, Plass T, Mueller V, Reymond L, Corrêa IR Jr, Luo ZG, Schultz C, Lemke EA, Heppenstall P, Eggeling C, Manley S, Johnsson K. (2013)
A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins
Nat Chem 5(2):132-139. doi: 10.1038/nchem.1546
Europe PMC | doi
Nadler A, Schultz C. (2013)
The power of fluorogenic probes
Angew. Chem. Int. Ed. Engl. 52(9):2408-2410. doi: 10.1002/anie.201209733
Europe PMC | doi
Adjobo-Hermans MJ, Crosby KC, Putyrski M, Bhageloe A, van Weeren L, Schultz C, Goedhart J, Gadella TW Jr. (2013)
PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq
Cell. Signal. 25(1):255-263. doi: 10.1016/j.cellsig.2012.09.022
Europe PMC | doi
Mishina NM, Markvicheva KN, Bilan DS, Matlashov ME, Shirmanova MV, Liebl D, Schultz C, Lukyanov S, Belousov VV. (2013)
Visualization of intracellular hydrogen peroxide with HyPer, a genetically encoded fluorescent probe
Meth. Enzymol. 526:45-59. doi: 10.1016/b978-0-12-405883-5.00003-x
Europe PMC | doi
Mishina NM, Markvicheva KN, Fradkov AF, Zagaynova EV, Schultz C, Lukyanov S, Belousov VV. (2013)
Imaging H2O2 microdomains in receptor tyrosine kinases signaling
Meth. Enzymol. 526:175-187. doi: 10.1016/b978-0-12-405883-5.00011-9
Europe PMC | doi
2012
Borrmann A, Milles S, Plass T, Dommerholt J, Verkade JM, Wiessler M, Schultz C, van Hest JC, van Delft FL, Lemke EA. (2012)
Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation
Chembiochem 13(14):2094-2099. doi: 10.1002/cbic.201200407
Europe PMC | doi
Wymann MP, Schultz C. (2012)
The chemical biology of phosphoinositide 3-kinases
Chembiochem 13(14):2022-2035. doi: 10.1002/cbic.201200089
Europe PMC | doi
Mishina NM, Bogeski I, Bolotin DA, Hoth M, Niemeyer BA, Schultz C, Zagaynova EV, Lukyanov S, Belousov VV. (2012)
Can we see PIP(3) and hydrogen peroxide with a single probe?
Antioxid. Redox Signal. 17(3):505-512. doi: 10.1089/ars.2012.4574
Europe PMC | doi
Rutkowska A, Schultz C. (2012)
Protein tango: the toolbox to capture interacting partners
Angew. Chem. Int. Ed. Engl. 51(33):8166-8176. doi: 10.1002/anie.201201717
Europe PMC | doi
Mundhenk L, Johannesson B, Anagnostopoulou P, Braun J, Bothe MK, Schultz C, Mall MA, Gruber AD. (2012)
mCLCA3 does not contribute to calcium-activated chloride conductance in murine airways
Am. J. Respir. Cell Mol. Biol. 47(1):87-93. doi: 10.1165/rcmb.2010-0508oc
Europe PMC | doi
Putyrski M, Schultz C. (2012)
Protein translocation as a tool: The current rapamycin story
FEBS Lett. 586(15):2097-2105. doi: 10.1016/j.febslet.2012.04.061
Europe PMC | doi
Gehrig S, Mall MA, Schultz C. (2012)
Spatially resolved monitoring of neutrophil elastase activity with ratiometric fluorescent reporters
Angew. Chem. Int. Ed. Engl. 51(25):6258-6261. doi: 10.1002/anie.201109226
Europe PMC | doi
Mertens HD, Piljić A, Schultz C, Svergun DI. (2012)
Conformational analysis of a genetically encoded FRET biosensor by SAXS
Biophys. J. 102(12):2866-2875. doi: 10.1016/j.bpj.2012.05.009
Europe PMC | doi
Plass T, Milles S, Koehler C, Szymański J, Mueller R, Wiessler M, Schultz C, Lemke EA. (2012)
Amino acids for Diels-Alder reactions in living cells
Angew. Chem. Int. Ed. Engl. 51(17):4166-4170. doi: 10.1002/anie.201108231
Europe PMC | doi
Cobos-Correa A, Stein F, Schultz C. (2012)
Target-Activated Prodrugs (TAPs) for the autoregulated inhibition of MMP12
ACS Med Chem Lett 3(8):653-657.
Europe PMC
Johannesson B, Hirtz S, Schatterny J, Schultz C, Mall MA. (2012)
CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice
PLoS ONE 7(8):e44059. doi: 10.1371/journal.pone.0044059
Europe PMC | doi
2011
Rutkowska A, Haering CH, Schultz C. (2011)
A FlAsH-based cross-linker to study protein interactions in living cells
Angew. Chem. Int. Ed. Engl. 50(52):12655-12658. doi: 10.1002/anie.201106404
Europe PMC | doi
Putyrski M, Schultz C. (2011)
Switching heterotrimeric G protein subunits with a chemical dimerizer
Chem. Biol. 18(9):1126-1133. doi: 10.1016/j.chembiol.2011.07.013
Europe PMC | doi
Lemke EA, Schultz C. (2011)
Principles for designing fluorescent sensors and reporters
Nat. Chem. Biol. 7(8):480-483. doi: 10.1038/nchembio.620
Europe PMC | doi
Piljić A, de Diego I, Wilmanns M, Schultz C. (2011)
Rapid development of genetically encoded FRET reporters
ACS Chem. Biol. 6(7):685-691. doi: 10.1021/cb100402n
Europe PMC | doi
Zhou Z, Duerr J, Johannesson B, Schubert SC, Treis D, Harm M, Graeber SY, Dalpke A, Schultz C, Mall MA. (2011)
The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease
J. Cyst. Fibros. 10 Suppl 2:S172-82. doi: 10.1016/s1569-1993(11)60021-0
Europe PMC | doi
Mentel M, Laketa V, Subramanian D, Gillandt H, Schultz C. (2011)
Photoactivatable and cell-membrane-permeable phosphatidylinositol 3,4,5-trisphosphate
Angew. Chem. Int. Ed. Engl. 50(16):3811-3814. doi: 10.1002/anie.201007796
Europe PMC | doi
Plass T, Milles S, Koehler C, Schultz C, Lemke EA. (2011)
Genetically encoded copper-free click chemistry
Angew. Chem. Int. Ed. Engl. 50(17):3878-3881. doi: 10.1002/anie.201008178
Europe PMC | doi
Schultz C, Aime S. (2011)
Imaging probes--Introduction
Bioorg. Med. Chem. 19(3):1022. doi: 10.1016/j.bmc.2011.01.040
Europe PMC | doi
Jackson SG, Al-Saigh S, Schultz C, Junop MS. (2011)
Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions
BMC Struct. Biol. 11:11. doi: 10.1186/1472-6807-11-11
Europe PMC | doi
Mishina NM, Tyurin-Kuzmin PA, Markvicheva KN, Vorotnikov AV, Tkachuk VA, Laketa V, Schultz C, Lukyanov S, Belousov VV. (2011)
Does cellular hydrogen peroxide diffuse or act locally?
Antioxid. Redox Signal. 14(1):1-7. doi: 10.1089/ars.2010.3539
Europe PMC | doi
Plass T, Schultz C. (2011)
Covalent labeling of biomolecules in living cells
In: Demchenko AP (ed.), Advanced Fluorescence Reporters in Chemistry and Biology III. Springer Series on Fluorescence. Springer Berlin Heidelberg. pp 225-261.doi: 10.1007/978-3-642-18035-4_7
Europe PMC | doi
2010
Mall MA, Button B, Johannesson B, Zhou Z, Livraghi A, Caldwell RA, Schubert SC, Schultz C, O'Neal WK, Pradervand S, Hummler E, Rossier BC, Grubb BR, Boucher RC. (2010)
Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice
J. Biol. Chem. 285(35):26945-26955. doi: 10.1074/jbc.m110.151803
Europe PMC | doi
Schultz C. (2010)
Challenges in studying phospholipid signaling
Nat. Chem. Biol. 6(7):473-475. doi: 10.1038/nchembio.389
Europe PMC | doi
Schultz C, Neef AB, Gadella TW Jr, Goedhart J. (2010)
Imaging lipids in living cells
Cold Spring Harb Protoc 2010(7):pdb.top83. doi: 10.1101/pdb.top83
Europe PMC | doi
Schultz C. (2010)
Climbing to the next step: photosensitive protein labels
ACS Chem. Biol. 5(5):447-448. doi: 10.1021/cb1001125
Europe PMC | doi
Subramanian D, Laketa V, Müller R, Tischer C, Zarbakhsh S, Pepperkok R, Schultz C. (2010)
Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells
Nat. Chem. Biol. 6(5):324-326. doi: 10.1038/nchembio.348
Europe PMC | doi
2009
Laketa V, Zarbakhsh S, Morbier E, Subramanian D, Dinkel C, Brumbaugh J, Zimmermann P, Pepperkok R, Schultz C. (2009)
Membrane-permeant phosphoinositide derivatives as modulators of growth factor signaling and neurite outgrowth
Chem. Biol. 16(11):1190-1196. doi: 10.1016/j.chembiol.2009.10.005
Europe PMC | doi
Cobos-Correa A, Trojanek JB, Diemer S, Mall MA, Schultz C. (2009)
Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation
Nat. Chem. Biol. 5(9):628-630. doi: 10.1038/nchembio.196
Europe PMC | doi
Köhn M, Schultz C. (2009)
Chemical biologists gather in Heidelberg
Nat. Chem. Biol. 5(2):66-69. doi: 10.1038/nchembio0209-66
Europe PMC | doi
Schultz C. (2009)
Fluorescent revelations
Chem. Biol. 16(2):107-111. doi: 10.1016/j.chembiol.2009.02.001
Europe PMC | doi
Neef AB, Schultz C. (2009)
Selective fluorescence labeling of lipids in living cells
Angew. Chem. Int. Ed. Engl. 48(8):1498-1500. doi: 10.1002/anie.200805507
Europe PMC | doi
2008
Piljić A, Schultz C. (2008)
Analysis of protein complex hierarchy in living cells
ACS Chem. Biol. 3(12):749-755. doi: 10.1021/cb8002539
Europe PMC | doi
Jost CA, Reither G, Hoffmann C, Schultz C. (2008)
Contribution of fluorophores to protein kinase C FRET probe performance
Chembiochem 9(9):1379-1384. doi: 10.1002/cbic.200700728
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