Thevathasan JV, Kahnwald M, Cieśliński K, Hoess P, Peneti SK, Reitberger M, Heid D, Kasuba KC, Hoerner SJ, Li Y, Wu YL, Mund M, Matti U, Pereira PM, Henriques R, Kueblbeck M, Nijmeijer B, Ellenberg J, Sabinina VJ, Ries J. (2019)

Nuclear pores as versatile reference standards for quantitative superresolution microscopy.

Nat. Methods 16(10):1045-1053. doi: 10.1038/s41592-019-0574-9
Europe PMC | doi

Müller R, Citir M, Hauke S, Schultz C. (2019)

Synthesis and cellular labeling of caged phosphatidylinositol derivatives.

Chemistry doi: 10.1002/chem.201903704
Europe PMC | doi

Schlichthaerle T, Strauss MT, Schueder F, Auer A, Nijmeijer B, Kueblbeck M, Sabinina VJ, Thevathasan JV, Ries J, Ellenberg J, Jungmann R. (2019)

Direct visualization of single nuclear pore complex proteins using genetically-encoded probes for DNA-PAINT.

Angew. Chem. Int. Ed. Engl. 58(37):13004-13008. doi: 10.1002/anie.201905685
Europe PMC | doi

Cattoglio C, Pustova I, Walther N, Ho JJ, Hantsche-Grininger M, Inouye CJ, Hossain MJ, Dailey GM, Ellenberg J, Darzacq X, Tjian R, Hansen AS. (2019)

Determining cellular CTCF and cohesin abundances to constrain 3D genome models.

Elife 8 doi: 10.7554/eLife.40164
Europe PMC | doi

Holzmann J, Politi AZ, Nagasaka K, Hantsche-Grininger M, Walther N, Koch B, Fuchs J, Dürnberger G, Tang W, Ladurner R, Stocsits RR, Busslinger GA, Novák B, Mechtler K, Davidson IF, Peters JM, Ellenberg J. (2019)

Absolute quantification of cohesin, CTCF and their regulators in human cells.

Elife 8 doi: 10.7554/eLife.46269
Europe PMC | doi

Ermakova YG, Mishina NM, Schultz C, Belousov VV. (2019)

Visualization of Intracellular Hydrogen Peroxide with the Genetically Encoded Fluorescent Probe HyPer in NIH-3T3 Cells.

Methods Mol. Biol. 1982:259-274. doi: 10.1007/978-1-4939-9424-3_15
Europe PMC | doi

Guerra M, Frey D, Hagner M, Dittrich S, Paulsen M, Mall MA, Schultz C. (2019)

Cathepsin G Activity as a New Marker for Detecting Airway Inflammation by Microscopy and Flow Cytometry.

ACS Cent Sci 5(3):539-548. doi: 10.1021/acscentsci.8b00933
Europe PMC | doi

Hauke S, Dutta AK, Eisenbeis VB, Bezold D, Bittner T, Wittwer C, Thakor D, Pavlovic I, Schultz C, Jessen HJ. (2019)

Photolysis of cell-permeant caged inositol pyrophosphates controls oscillations of cytosolic calcium in a β-cell line.

Chem Sci 10(9):2687-2692. doi: 10.1039/c8sc03479f
Europe PMC | doi

Schneider I, Ellenberg J. (2019)

Mysteries in embryonic development: How can errors arise so frequently at the beginning of mammalian life?

PLoS Biol. 17(3) doi: 10.1371/journal.pbio.3000173
Europe PMC | doi

Baser A, Skabkin M, Kleber S, Dang Y, Gülcüler Balta GS, Kalamakis G, Göpferich M, Ibañez DC, Schefzik R, Lopez AS, Bobadilla EL, Schultz C, Fischer B, Martin-Villalba A. (2019)

Onset of differentiation is post-transcriptionally controlled in adult neural stem cells.

Nature 566(7742) doi: 10.1038/s41586-019-0888-x
Europe PMC | doi

Frank JA, Broichhagen J, Yushchenko DA, Trauner D, Schultz C, Hodson DJ. (2018)

Optical tools for understanding the complexity of β-cell signalling and insulin release.

Nat Rev Endocrinol 14(12):721-737. doi: 10.1038/s41574-018-0105-2
Europe PMC | doi

Kirby IT, Kojic A, Arnold MR, Thorsell AG, Karlberg T, Vermehren-Schmaedick A, Sreenivasan R, Schultz C, Schüler H, Cohen MS. (2018)

A potent and selective PARP11 inhibitor suggests coupling between cellular localization and catalytic activity.

Cell Chem Biol 25(12):1547-1553.e12. doi: 10.1016/j.chembiol.2018.09.011
Europe PMC | doi

Pękowska A, Klaus B, Xiang W, Severino J, Daigle N, Klein FA, Oleś M, Casellas R, Ellenberg J, Steinmetz LM, Bertone P, Huber W. (2018)

Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency.

Cell Syst 7(5) doi: 10.1016/j.cels.2018.09.003
Europe PMC | doi

Hauke S, Keutler K, Phapale P, Yushchenko DA, Schultz C. (2018)

Endogenous Fatty Acids are Essential Signaling Factors of Pancreatic β-Cells and Insulin Secretion.

Diabetes 67(10) doi: 10.2337/db17-1215
Europe PMC | doi

Ellenberg J, Swedlow JR, Barlow M, Cook CE, Sarkans U, Patwardhan A, Brazma A, Birney E. (2018)

A call for public archives for biological image data.

Nat. Methods 15(11):849-854. doi: 10.1038/s41592-018-0195-8
Europe PMC | doi

Popovic D, Koch B, Kueblbeck M, Ellenberg J, Pelkmans L. (2018)

Multivariate Control of Transcript to Protein Variability in Single Mammalian Cells.

Cell Syst 7(4) doi: 10.1016/j.cels.2018.09.001
Europe PMC | doi

Strauss S, Nickels PC, Strauss MT, Jimenez Sabinina V, Ellenberg J, Carter JD, Gupta S, Janjic N, Jungmann R. (2018)

Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging.

Nat Methods 15(9) doi: 10.1038/s41592-018-0105-0
Europe PMC | doi

Cai Y, Hossain MJ, Hériché JK, Politi AZ, Walther N, Koch B, Wachsmuth M, Nijmeijer B, Kueblbeck M, Martinic-Kavur M, Ladurner R, Alexander S, Peters JM, Ellenberg J. (2018)

Experimental and computational framework for a dynamic protein atlas of human cell division.

Nature 561(7723) doi: 10.1038/s41586-018-0518-z
Europe PMC | doi

Yu X, Akbarzadeh R, Pieper M, Scholzen T, Gehrig S, Schultz C, Zillikens D, König P, Petersen F. (2018)

Neutrophil adhesion is a prerequisite for antibody-mediated proteolytic tissue damage in experimental epidermolysis bullosa acquisita.

J Invest Dermatol 138(9) doi: 10.1016/j.jid.2018.03.1499
Europe PMC | doi

Hoffmann JE, Dziuba D, Stein F, Schultz C. (2018)

A Bifunctional Noncanonical Amino Acid: Synthesis, Expression, and Residue-Specific Proteome-wide Incorporation.

Biochemistry 57(31) doi: 10.1021/acs.biochem.8b00397
Europe PMC | doi

Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Hériché JK, Wutz G, van der Lelij P, Kreidl E, Hutchins JR, Axelsson-Ekker H, Ellenberg J, Hyman AA, Peters JM, Mechtler K. (2018)

The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.

EMBO J. 37(15) doi: 10.15252/embj.201797150
Europe PMC | doi

Laguerre A, Schultz C. (2018)

Novel lipid tools and probes for biological investigations.

Curr. Opin. Cell Biol. 53:97-104. doi: 10.1016/j.ceb.2018.06.013
Europe PMC | doi

Reichmann J, Nijmeijer B, Hossain MJ, Eguren M, Schneider I, Politi AZ, Roberti MJ, Hufnagel L, Hiiragi T, Ellenberg J. (2018)

Dual-spindle formation in zygotes keeps parental genomes apart in early mammalian embryos.

Science 361(6398):189-193. doi: 10.1126/science.aar7462
Europe PMC | doi

Walther N, Hossain MJ, Politi AZ, Koch B, Kueblbeck M, Ødegård-Fougner Ø, Lampe M, Ellenberg J. (2018)

A quantitative map of human Condensins provides new insights into mitotic chromosome architecture.

J Cell Biol 217(7) doi: 10.1083/jcb.201801048
Europe PMC | doi

Koch B, Nijmeijer B, Kueblbeck M, Cai Y, Walther N, Ellenberg J. (2018)

Generation and validation of homozygous fluorescent knock-in cells using CRISPR-Cas9 genome editing.

Nat Protoc 13(6):1465-1487. doi: 10.1038/nprot.2018.042
Europe PMC | doi

Politi AZ, Cai Y, Walther N, Hossain MJ, Koch B, Wachsmuth M, Ellenberg J. (2018)

Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four-dimensional imaging.

Nat Protoc 13(6):1445-1464. doi: 10.1038/nprot.2018.040
Europe PMC | doi

iNEXT Consortium. (2018)

iNEXT: a European facility network to stimulate translational structural biology.

FEBS Lett. 592(12) doi: 10.1002/1873-3468.13062
Europe PMC | doi

Xiang W, Roberti MJ, Hériché JK, Huet S, Alexander S, Ellenberg J. (2018)

Correction: Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.

J Cell Biol 217(9):3315-3316. doi: 10.1083/JCB.20170907408082018c
Europe PMC | doi

Xiang W, Roberti MJ, Hériché JK, Huet S, Alexander S, Ellenberg J. (2018)

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.

J Cell Biol 217(6) doi: 10.1083/jcb.201709074
Europe PMC | doi

Li Y, Mund M, Hoess P, Deschamps J, Matti U, Nijmeijer B, Sabinina VJ, Ellenberg J, Schoen I, Ries J. (2018)

Real-time 3D single-molecule localization using experimental point spread functions.

Nat Methods 15(5) doi: 10.1038/nmeth.4661
Europe PMC | doi

Reichmann J, Eguren M, Lin Y, Schneider I, Ellenberg J. (2018)

Live imaging of cell division in preimplantation mouse embryos using inverted light-sheet microscopy.

Methods Cell Biol. 145:279-292. doi: 10.1016/bs.mcb.2018.03.030
Europe PMC | doi

Walther N, Ellenberg J. (2018)

Quantitative live and super-resolution microscopy of mitotic chromosomes

Methods Cell Biol. doi: 10.1016/bs.mcb.2018.03.014
Europe PMC | doi

Kath C, Goni-Oliver P, Müller R, Schultz C, Haucke V, Eickholt B, Schmoranzer J. (2018)

PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules.

PLoS One 13(4) doi: 10.1371/journal.pone.0193257
Europe PMC | doi

Dittrich AS, Kühbandner I, Gehrig S, Rickert-Zacharias V, Twigg M, Wege S, Taggart CC, Herth F, Schultz C, Mall MA. (2018)

Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis.

Eur Respir J 51(3) doi: 10.1183/13993003.01910-2017
Europe PMC | doi

Barton C, Morganella S, Ødegård-Fougner Ø, Alexander S, Ries J, Fitzgerald T, Ellenberg J, Birney E. (2018)

ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy.

PLoS Comput Biol 14(3) doi: 10.1371/journal.pcbi.1006002
Europe PMC | doi

Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T. (2018)

Author Correction: Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.

Nat. Cell Biol. 20(4) doi: 10.1038/s41556-018-0044-0
Europe PMC | doi

Otsuka S, Ellenberg J. (2018)

Mechanisms of nuclear pore complex assembly: Two different ways of building one molecular machine

FEBS letters 592(4) doi: 10.1002/1873-3468.12905
Europe PMC | doi

Otsuka S, Steyer AM, Schorb M, Hériché JK, Hossain MJ, Sethi S, Kueblbeck M, Schwab Y, Beck M, Ellenberg J. (2018)

Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings

Nat. Struct. Mol. Biol. 25(1):21-28. doi: 10.1038/s41594-017-0001-9
Europe PMC | doi

Wutz G, Várnai C, Nagasaka K, Cisneros DA, Stocsits RR, Tang W, Schoenfelder S, Jessberger G, Muhar M, Hossain MJ, Walther N, Koch B, Kueblbeck M, Ellenberg J, Zuber J, Fraser P, Peters JM. (2017)

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.

EMBO J. 36(24) doi: 10.15252/embj.201798004
Europe PMC | doi

Walter AM, Müller R, Tawfik B, Wierda KD, Pinheiro PS, Nadler A, McCarthy AW, Ziomkiewicz I, Kruse M, Reither G, Rettig J, Lehmann M, Haucke V, Hille B, Schultz C, Sorensen JB. (2017)

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis.

Elife 6 doi: 10.7554/eLife.30203
Europe PMC | doi

Germier T, Kocanova S, Walther N, Bancaud A, Shaban HA, Sellou H, Politi AZ, Ellenberg J, Gallardo F, Bystricky K. (2017)

Real-Time Imaging of a Single Gene Reveals Transcription-Initiated Local Confinement.

Biophys. J. 113(7):1383-1394. doi: 10.1016/j.bpj.2017.08.014
Europe PMC | doi

Frank JA, Yushchenko DA, Fine NHF, Duca M, Citir M, Broichhagen J, Hodson DJ, Schultz C, Trauner D. (2017)

Optical control of GPR40 signalling in pancreatic beta-cells

CHEM SCI 8(11):7604-7610. doi: 10.1039/c7sc01475a
Europe PMC | doi

Bogdanova YA, Schultz C, Belousov VV. (2017)

Local Generation and Imaging of Hydrogen Peroxide in Living Cells.

Curr Protoc Chem Biol 9(2):117-127. doi: 10.1002/cpch.20
Europe PMC | doi

Marat AL, Wallroth A, Lo WT, Müller R, Norata GD, Falasca M, Schultz C, Haucke V. (2017)

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate.

Science 356(6341):968-972. doi: 10.1126/science.aaf8310
Europe PMC | doi

Mücksch F, Laketa V, Müller B, Schultz C, Kräusslich HG. (2017)

Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring.

Elife 6 doi: 10.7554/eLife.25287
Europe PMC | doi

Zuidscherwoude M, Dunlock VE, van den Bogaart G, van Deventer SJ, van der Schaaf A, van Oostrum J, Goedhart J, In 't Hout J, Hämmerling GJ, Tanaka S, Nadler A, Schultz C, Wright MD, Adjobo-Hermans MJW, van Spriel AB. (2017)

Tetraspanin microdomains control localized protein kinase C signaling in B cells.

Sci Signal 10(478):1-15. doi: 10.1126/scisignal.aag2755
Europe PMC | doi

Schifferer M, Yushchenko DA, Stein F, Bolbat A, Schultz C. (2017)

A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells.

Cell Chem Biol 24(4):525-531. doi: 10.1016/j.chembiol.2017.03.001
Europe PMC | doi

Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A. (2017)

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Dev. Cell 40(4):331-341. doi: 10.1016/j.devcel.2017.01.015
Europe PMC | doi

Höglinger D, Nadler A, Haberkant P, Kirkpatrick J, Schifferer M, Stein F, Hauke S, Porter FD, Schultz C. (2017)

Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.

Proc. Natl. Acad. Sci. U.S.A. 114(7):1566-1571. doi: 10.1073/pnas.1611096114
Europe PMC | doi

Taggart C, Mall MA, Lalmanach G, Cataldo D, Ludwig A, Janciauskiene S, Heath N, Meiners S, Overall CM, Schultz C, Turk B, Borensztajn KS. (2017)

Protean proteases: at the cutting edge of lung diseases.

Eur. Respir. J. 49(2) doi: 10.1183/13993003.01200-2015
Europe PMC | doi

Papadopoulos T, Rhee HJ, Subramanian D, Paraskevopoulou F, Mueller R, Schultz C, Brose N, Rhee JS, Betz H. (2017)

Endosomal Phosphatidylinositol 3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses.

J. Biol. Chem. 292(4):1160-1177. doi: 10.1074/jbc.M116.771592
Europe PMC | doi

Schifferer M, Feng S, Stein F, Schultz C. (2017)

Reversible Chemical Dimerization by rCD1.

Meth. Enzymol. 583:173-195. doi: 10.1016/bs.mie.2016.10.035
Europe PMC | doi

Kuchenov D, Laketa V, Stein F, Salopiata F, Klingmüller U, Schultz C. (2016)

High-Content Imaging Platform for Profiling Intracellular Signaling Network Activity in Living Cells.

Cell Chem Biol 23(12):1550-1559. doi: 10.1016/j.chembiol.2016.11.008
Europe PMC | doi

S Pedersen R, Karemore G, Gudjonsson T, Rask MB, Neumann B, Hériché JK, Pepperkok R, Ellenberg J, Gerlich DW, Lukas J, Lukas C. (2016)

Profiling DNA damage response following mitotic perturbations.

Nat Commun 7(13887):1-12. doi: 10.1038/ncomms13887
Europe PMC | doi

Wagner CJ, Schultz C, Mall MA. (2016)

Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease.

Mol Cell Pediatr 3(1) doi: 10.1186/s40348-016-0053-7
Europe PMC | doi

Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, Landry JJ, Fritz MH, Radic K, Hoffmann JE, Chen ZA, Zou J, Tan PS, Galik B, Junttila S, Stolt-Bergner P, Pruneri G, Gyenesei A, Schultz C, Biskup MB, Besir H, Benes V, Rappsilber J, Jechlinger M, Korbel JO, Berger I, Braese S, Lemke EA. (2016)

Genetic code expansion for multiprotein complex engineering.

Nat. Methods 13(12) doi: 10.1038/nmeth.4032
Europe PMC | doi

Bolbat A, Schultz C. (2016)

Recent developments of genetically encoded optical sensors for cell biology.

Biol. Cell 109(1) doi: 10.1111/boc.201600040
Europe PMC | doi

Otsuka S, Bui KH, Schorb M, Hossain MJ, Politi AZ, Koch B, Eltsov M, Beck M, Ellenberg J. (2016)

Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope

Elife 5 doi: 10.7554/eLife.19071
Europe PMC | doi

Rickert-Zacharias V, Schultz C, Mall MA. (2016)

A Protease Inhibitor Tackles Epithelial Sodium Channels in Cystic Fibrosis.

Am. J. Respir. Crit. Care Med. 194(6):650-652. doi: 10.1164/rccm.201604-0781ed
Europe PMC | doi

Uhlen M, Bandrowski A, Carr S, Edwards A, Ellenberg J, Lundberg E, Rimm DL, Rodriguez H, Hiltke T, Snyder M, Yamamoto T. (2016)

A proposal for validation of antibodies.

Nat. Methods 13(10) doi: 10.1038/nmeth.3995
Europe PMC | doi

Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee JS, Gottschalk A, Brose N, Schultz C, Trauner D. (2016)

Photoswitchable diacylglycerols enable optical control of protein kinase C.

Nat. Chem. Biol. 12(9):755-762. doi: 10.1038/nchembio.2141
Europe PMC | doi

Cuylen S, Blaukopf C, Politi AZ, Müller-Reichert T, Neumann B, Poser I, Ellenberg J, Hyman AA, Gerlich DW. (2016)

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.

Nature 535(7611):308-312. doi: 10.1038/nature18610
Europe PMC | doi

Bilgin M, Born P, Fezza F, Heimes M, Mastrangelo N, Wagner N, Schultz C, Maccarrone M, Eaton S, Nadler A, Wilm M, Shevchenko A. (2016)

Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS.

Sci Rep 6:27920. doi: 10.1038/srep27920
Europe PMC | doi

Simon B, Huart A, Temmerman K, Vahokoski J, Mertens H, Komadina D, Hoffmann J, Yumerefendi H, Svergun D, Kursula P, Schultz C, McCarthy A, Hart D, Wilmanns M. (2016)

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

Structure 24(6):851-861. doi: 10.1016/j.str.2016.03.020
Europe PMC | doi

Saliba AE, Vonkova I, Deghou S, Ceschia S, Tischer C, Kugler KG, Bork P, Ellenberg J, Gavin AC. (2016)

A protocol for the systematic and quantitative measurement of protein-lipid interactions using the liposome-microarray-based assay.

Nat Protoc 11(6):1021-1038. doi: 10.1038/nprot.2016.059
Europe PMC | doi

Jupp S, Malone J, Burdett T, Heriche JK, Williams E, Ellenberg J, Parkinson H, Rustici G. (2016)

The cellular microscopy phenotype ontology.

J Biomed Semantics 7:28. doi: 10.1186/s13326-016-0074-0
Europe PMC | doi

Hövelmann F, Kedziora KM, Nadler A, Müller R, Jalink K, Schultz C. (2016)

Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient.

Cell Chem Biol 23(5) doi: 10.1016/j.chembiol.2015.11.019
Europe PMC | doi

Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T. (2016)

Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.

Nat. Cell Biol. 18(6):692-699. doi: 10.1038/ncb3353
Europe PMC | doi

Gerl MJ, Bittl V, Kirchner S, Sachsenheimer T, Brunner HL, Lüchtenborg C, Özbalci C, Wiedemann H, Wegehingel S, Nickel W, Haberkant P, Schultz C, Krüger M, Brügger B. (2016)

Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.

PLoS ONE 11(4) doi: 10.1371/journal.pone.0153009
Europe PMC | doi

Yushchenko DA, Nadler A, Schultz C. (2016)

Manipulating cell signaling with subcellular spatial resolution

Cell Cycle 15(8):1023-1024. doi: 10.1080/15384101.2016.1157974
Europe PMC | doi

Isokane M, Walter T, Mahen R, Nijmeijer B, Hériché JK, Miura K, Maffini S, Ivanov MP, Kitajima TS, Peters JM, Ellenberg J. (2016)

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.

J. Cell Biol. 212(6):647-659. doi: 10.1083/jcb.201408089
Europe PMC | doi

Samarin J, Laketa V, Malz M, Roessler S, Stein I, Horwitz E, Singer S, Dimou E, Cigliano A, Bissinger M, Falk CS, Chen X, Dooley S, Pikarsky E, Calvisi DF, Scultzh C, Schirmacher P, Breuhahn K. (2016)

PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells.

Hepatology 63(3):813-826. doi: 10.1002/hep.28357
Europe PMC | doi

Pavlovic I, Thakor DT, Vargas JR, McKinlay CJ, Hauke S, Anstaett P, Camuña RC, Bigler L, Gasser G, Schultz C, Wender PA, Jessen HJ. (2016)

Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo.

Nat Commun 7(10622) doi: 10.1038/ncomms10622
Europe PMC | doi

Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de Medeiros G, Norlin N, Hiiragi T, Hufnagel L, Ellenberg J. (2016)

Inverted light-sheet microscope for imaging mouse pre-implantation development.

Nat. Methods 13(2):139-142. doi: 10.1038/nmeth.3690
Europe PMC | doi

Ketel K, Krauss M, Nicot AS, Puchkov D, Wieffer M, Müller R, Subramanian D, Schultz C, Laporte J, Haucke V. (2016)

A phosphoinositide conversion mechanism for exit from endosomes.

Nature 529(7586):408-12. doi: 10.1038/nature16516
Europe PMC | doi

Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C. (2016)

Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions.

ACS Chem Biol 11(1):222-230. doi: 10.1021/acschembio.5b00810
Europe PMC | doi

Nadler A, Yushchenko DA, Müller R, Stein F, Feng S, Mulle C, Carta M, Schultz C. (2015)

Exclusive photorelease of signalling lipids at the plasma membrane.

Nat Commun 6 doi: 10.1038/ncomms10056
Europe PMC | doi

Hu HY, Lim NH, Juretschke HP, Ding-Pfennigdorff D, Florian P, Kohlmann M, Kandira A, von Kries JP, Saas J, Rudolphi KA, Wendt KU, Nagase H, Plettenburg O, Nazare M, Schultz C. (2015)

In vivo visualization of osteoarthritic hypertrophic lesions

Chem Sci 6(11):6256-6261. doi: 10.1039/c5sc01301a
Europe PMC | doi

Höglinger D, Haberkant P, Aguilera-Romero A, Riezman H, Porter FD, Platt FM, Galione A, Schultz C. (2015)

Intracellular sphingosine releases calcium from lysosomes.

Elife 4 doi: 10.7554/eLife.10616
Europe PMC | doi

Mardin BR, Drainas AP, Waszak SM, Weischenfeldt J, Isokane M, Stütz AM, Raeder B, Efthymiopoulos T, Buccitelli C, Segura-Wang M, Northcott P, Pfister SM, Lichter P, Ellenberg J, Korbel JO. (2015)

A cell-based model system links chromothripsis with hyperploidy.

Mol. Syst. Biol. 11(9):828. doi: 10.15252/msb.20156505
Europe PMC | doi

Vonkova I, Saliba AE, Deghou S, Anand K, Ceschia S, Doerks T, Galih A, Kugler KG, Maeda K, Rybin V, van Noort V, Ellenberg J, Bork P, Gavin AC. (2015)

Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains.

Cell Rep 12(9):1519-1530. doi: 10.1016/j.celrep.2015.07.054
Europe PMC | doi

Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. (2015)

Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling.

Chem-Eur J 21(35):12266-12270. doi: 10.1002/chem.201501647
Europe PMC | doi

Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. (2015)

Frontispiece: Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling.

Chemistry 21(35) doi: 10.1002/chem.201583561
Europe PMC | doi

MacNamara A, Stein F, Feng S, Schultz C, Saez-Rodriguez J. (2015)

A single-cell model of PIP3 dynamics using chemical dimerization.

Bioorg. Med. Chem. 23(12) doi: 10.1016/j.bmc.2015.04.074
Europe PMC | doi

Schifferer M, Feng S, Stein F, Tischer C, Schultz C. (2015)

Reversible chemical dimerizer-induced recovery of PIP2 levels moves clathrin to the plasma membrane.

Bioorg. Med. Chem. 23(12):2862-2867. doi: 10.1016/j.bmc.2015.03.048
Europe PMC | doi

Boni A, Politi AZ, Strnad P, Xiang W, Hossain MJ, Ellenberg J. (2015)

Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells.

J. Cell Biol. 209(5):705-720. doi: 10.1083/jcb.201409133
Europe PMC | doi

Bertozzi CR, Stockwell BR, Kubicek S, Dickinson BC, Chang CJ, Schultz C, Silver PA, Gestwicki JE, Chiosis G, Chattopadhyay A, Butcher RA, Park SB, Shoichet BK, Flitsch SL, Zhang J, Liu DR, Ohnishi Y, Weerapana E, Williams AH, He C, Moroni A, Thiel G, Chang YT, Waldmann H, Bogyo M, Oddershede LB, Christopoulos A, Imperiali B, Ehrlich H, Chen X, Prescher JA. (2015)

Voices of chemical biology

Nat. Chem. Biol. 11(6):378-379. doi: 10.1038/nchembio.1820
Europe PMC | doi

Mishina NM, Mishin AS, Belyaev Y, Bogdanova EA, Lukyanov S, Schultz C, Belousov VV. (2015)

Live-Cell STED Microscopy with Genetically Encoded Biosensor

Nano Lett. 15(5):2928-2932. doi: 10.1021/nl504710z
Europe PMC | doi

Hu HY, Lim NH, Ding-Pfennigdorff D, Saas J, Wendt KU, Ritzeler O, Nagase H, Plettenburg O, Schultz C, Nazare M. (2015)

DOTAM Derivatives as Active Cartilage-Targeting Drug Carriers for the Treatment of Osteoarthritis

Bioconjugate Chem. 26(3):383-388. doi: 10.1021/bc500557s
Europe PMC | doi

Wachsmuth M, Conrad C, Bulkescher J, Koch B, Mahen R, Isokane M, Pepperkok R, Ellenberg J. (2015)

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.

Nat. Biotechnol. 33(4):384-389. doi: 10.1038/nbt.3146
Europe PMC | doi

Lees JG, Hériché JK, Morilla I, Fernández JM, Adler P, Krallinger M, Vilo J, Valencia A, Ellenberg J, Ranea JA, Orengo C. (2015)

FUN-L: Gene prioritization for RNAi screens.

Bioinformatics 31(12):2052-2053. doi: 10.1093/bioinformatics/btv073
Europe PMC | doi

Solc P, Kitajima TS, Yoshida S, Brzakova A, Kaido M, Baran V, Mayer A, Samalova P, Motlik J, Ellenberg J. (2015)

Multiple Requirements of PLK1 during Mouse Oocyte Maturation.

PLoS ONE 10(2) doi: 10.1371/journal.pone.0116783
Europe PMC | doi

van der Lelij P, Stocsits RR, Ladurner R, Petzold G, Kreidl E, Koch B, Schmitz J, Neumann B, Ellenberg J, Peters JM. (2014)

SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs

EMBO J. 33(22):2643-2658. doi: 10.15252/embj.201488202
Europe PMC | doi

Mahen R, Koch B, Wachsmuth M, Politi AZ, Perez-Gonzalez A, Mergenthaler J, Cai Y, Ellenberg J. (2014)

Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells

Mol. Biol. Cell 25(22):3610-3618. doi: 10.1091/mbc.e14-06-1091
Europe PMC | doi

Rohn JL, Patel JV, Neumann B, Bulkescher J, Mchedlishvili N, McMullan RC, Quintero OA, Ellenberg J, Baum B. (2014)

Myo19 Ensures Symmetric Partitioning of Mitochondria and Coupling of Mitochondrial Segregation to Cell Division.

Curr. Biol. 24(21):2598-2605. doi: 10.1016/j.cub.2014.09.045
Europe PMC | doi

Trojanek JB, Cobos-Correa A, Diemer S, Kormann M, Schubert SC, Zhou-Suckow Z, Agrawal R, Duerr J, Wagner CJ, Schatterny J, Hirtz S, Sommerburg O, Hartl D, Schultz C, Mall MA. (2014)

Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema

Am. J. Respir. Cell Mol. Biol. 51(5):709-720. doi: 10.1165/rcmb.2013-0407oc
Europe PMC | doi

Tegha-Dunghu J, Bausch E, Neumann B, Wuensche A, Walter T, Ellenberg J, Gruss OJ. (2014)

MAP1S controls microtubule stability throughout the cell cycle in human cells.

J. Cell. Sci. 127(23):5007-5013. doi: 10.1242/jcs.136457
Europe PMC | doi

Rutkowska A, Plass T, Hoffmann JE, Yushchenko DA, Feng S, Schultz C. (2014)

T-CrAsH: A Heterologous Chemical Crosslinker

Chembiochem 15(12):1765-1768. doi: 10.1002/cbic.201402189
Europe PMC | doi

Hériché JK, Lees JG, Morilla I, Walter T, Petrova B, Roberti MJ, Hossain MJ, Adler P, Fernández JM, Krallinger M, Haering CH, Vilo J, Valencia A, Ranea JA, Orengo C, Ellenberg J. (2014)

Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation

Mol. Biol. Cell 25(16):2522-2536. doi: 10.1091/mbc.e13-04-0221
Europe PMC | doi

Höglinger D, Nadler A, Schultz C. (2014)

Caged lipids as tools for investigating cellular signaling

Biochim. Biophys. Acta 1841(8):1085-1096. doi: 10.1016/j.bbalip.2014.03.012
Europe PMC | doi