EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Biography

  • PhD 2010, Dartmouth College.
    Postdoctoral research at Princeton University and Howard Hughes Medical Institute’s Janelia Research Campus.
    Group leader at EMBL since 2017.

Publications

Total: 13 publication(s)

2017

Tsai A, Muthusamy AK, Alves MR, Lavis LD, Singer RH, Stern DL, Crocker J. (2017)

Nuclear microenvironments modulate transcription from low-affinity enhancers.

Elife doi: 10.7554/elife.28975
Europe PMC | doi

Crocker J, Ilsley GR. (2017)

Using synthetic biology to study gene regulatory evolution.

Curr Opin Genet Dev 47:91-101. doi: 10.1016/j.gde.2017.09.001
Europe PMC | doi

Crocker J, Stern DL. (2017)

Functional regulatory evolution outside of the minimal even-skipped stripe 2 enhancer.

Development doi: 10.1242/dev.149427
Europe PMC | doi

Stern DL, Crocker J, Ding Y, Frankel N, Kappes G, Kim E, Kuzmickas R, Lemire A, Mast JD, Picard S. (2017)

Genetic and Transgenic Reagents for Drosophila simulans, D-mauritiana, D-yakuba, D-santomea, and D-virilis

G3 (Bethesda) 7:1339-1347. doi: 10.1534/g3.116.038885
Europe PMC | doi

Crocker J, Tsai A, Stern DL. (2017)

A Fully Synthetic Transcriptional Platform for a Multicellular Eukaryote

Cell Rep 18(1):287-296. doi: 10.1016/j.celrep.2016.12.025
Europe PMC | doi


2016

Crocker J, Noon EP, Stern DL. (2016)

The Soft Touch: Low-Affinity Transcription Factor Binding Sites in Development and Evolution

Curr Top Dev Biol 117:455-469. doi: 10.1016/bs.ctdb.2015.11.018
Europe PMC | doi

Crocker J, Ilsley GR, Stern DL. (2016)

Quantitatively predictable control of Drosophila transcriptional enhancers in vivo with engineered transcription factors

Nat Genet 48(3):292-298. doi: 10.1038/ng.3509
Europe PMC | doi


2015

Crocker J, Abe N, Rinaldi L, McGregor AP, Frankel N, Wang S, Alsawadi A, Valenti P, Plaza S, Payre F, Mann RS, Stern DL. (2015)

Low affinity binding site clusters confer hox specificity and regulatory robustness

Cell 160(1-2):191-203. doi: 10.1016/j.cell.2014.11.041
Europe PMC | doi


2013

Crocker J, Stern DL. (2013)

TALE-mediated modulation of transcriptional enhancers in vivo

Nat Methods 10(8):762-767. doi: 10.1038/nmeth.2543
Europe PMC | doi

Crocker J, Erives A. (2013)

A Schnurri/Mad/Medea complex attenuates the dorsal-twist gradient readout at vnd.

Dev Biol 378(1):64-72. doi: 10.1016/j.ydbio.2013.03.002
Europe PMC | doi


2010

Crocker J, Potter N, Erives A. (2010)

Dynamic evolution of precise regulatory encodings creates the clustered site signature of enhancers.

Nat Commun 1 doi: 10.1038/ncomms1102
Europe PMC | doi


2008

Crocker J, Tamori Y, Erives A. (2008)

Evolution acts on enhancer organization to fine-tune gradient threshold readouts.

PLoS Biol. 6(11):2576-2587. doi: 10.1371/journal.pbio.0060263
Europe PMC | doi

Crocker J, Erives A. (2008)

A Closer Look at the eve Stripe 2 Enhancers of Drosophila and Themira

PLoS Genet. 4 doi: 10.1371/journal.pgen.1000276
Europe PMC | doi