Total: 283 publication(s)


Gebauer F, Schwarzl T, Valcárcel J, Hentze MW. (2020)

RNA-binding proteins in human genetic disease.

Nat Rev Genet 22(3) doi: 10.1038/s41576-020-00302-y
Europe PMC | doi

Perez-Perri JI, Noerenberg M, Kamel W, Lenz CE, Mohammed S, Hentze MW, Castello A. (2020)

Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture.

Nat Protoc 16(1):27-60. doi: 10.1038/s41596-020-00404-1
Europe PMC | doi

Iserman C, Desroches Altamirano C, Jegers C, Friedrich U, Zarin T, Fritsch AW, Mittasch M, Domingues A, Hersemann L, Jahnel M, Richter D, Guenther UP, Hentze MW, Moses AM, Hyman AA, Kreysing M, Kramer G, Alberti S, Franzmann TM. (2020)

Condensation of Ded1p promotes a translational switch from housekeeping to stress protein production.

Cell 181(4):818-831.e19. doi: 10.1016/j.cell.2020.04.009
Europe PMC | doi

Backlund M, Stein F, Rettel M, Schwarzl T, Perez-Perri JI, Brosig A, Zhou Y, Neu-Yilik G, Hentze MW, Kulozik AE. (2020)

Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins.

Nucleic Acids Res. 48(9) doi: 10.1093/nar/gkaa256
Europe PMC | doi

Büscher M, Horos R, Hentze MW. (2020)

'High vault-age': non-coding RNA control of autophagy.

Open Biol 10(2) doi: 10.1098/rsob.190307
Europe PMC | doi

Dziuba D, Hoffmann JE, Hentze MW, Schultz C. (2020)

A genetically encoded diazirine analogue for RNA-protein photocrosslinking.

Chembiochem 21(1-2):88-93. doi: 10.1002/cbic.201900559
Europe PMC | doi


Cooke A, Schwarzl T, Huppertz I, Kramer G, Mantas P, Alleaume AM, Huber W, Krijgsveld J, Hentze MW. (2019)

The RNA-binding protein YBX3 controls amino acid levels by regulating SLC mRNA abundance.

Cell Rep 27(11):3097-3106.e5. doi: 10.1016/j.celrep.2019.05.039
Europe PMC | doi

Horos R, Büscher M, Sachse C, Hentze MW. (2019)

Vault RNA emerges as a regulator of selective autophagy.

Autophagy 15(8) doi: 10.1080/15548627.2019.1609861
Europe PMC | doi

Vinchi F, Porto G, Simmelbauer A, Altamura S, Passos ST, Garbowski M, Silva AMN, Spaich S, Seide SE, Sparla R, Hentze MW, Muckenthaler MU. (2019)

Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction.

Eur. Heart J. 41(28) doi: 10.1093/eurheartj/ehz112
Europe PMC | doi

Horos R, Büscher M, Kleinendorst R, Alleaume AM, Tarafder AK, Schwarzl T, Dziuba D, Tischer C, Zielonka EM, Adak A, Castello A, Huber W, Sachse C, Hentze MW. (2019)

The small non-coding vault RNA1-1 acts as a riboregulator of autophagy.

Cell 176(5):1054-1067.e12. doi: 10.1016/j.cell.2019.01.030
Europe PMC | doi

Trendel J, Schwarzl T, Horos R, Prakash A, Bateman A, Hentze MW, Krijgsveld J. (2019)

The human RNA-binding proteome and its dynamics during translational arrest.

Cell 176(1-2):391-403.e19. doi: 10.1016/j.cell.2018.11.004
Europe PMC | doi


Perez-Perri JI, Rogell B, Schwarzl T, Stein F, Zhou Y, Rettel M, Brosig A, Hentze MW. (2018)

Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture.

Nat Commun 9(1) doi: 10.1038/s41467-018-06557-8
Europe PMC | doi

Asencio C, Chatterjee A, Hentze MW. (2018)

Silica-based solid-phase extraction of cross-linked nucleic acid-bound proteins.

Life Sci Alliance 1(3) doi: 10.26508/lsa.201800088
Europe PMC | doi

Hentze MW, Valcárcel J.. (2018)

Elisa Izaurralde 1959-2018.

Nat. Struct. Mol. Biol. 25(7) doi: 10.1038/s41594-018-0081-1
Europe PMC | doi

Hentze MW, Castello A, Schwarzl T, Preiss T. (2018)

A brave new world of RNA-binding proteins.

Nat Rev Mol Cell Biol 19(5):327-341. doi: 10.1038/nrm.2017.130
Europe PMC | doi

Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A. (2018)

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

Nat Commun 9(1) doi: 10.1038/s41467-018-04092-0
Europe PMC | doi


Castello A, Frese CK, Fischer B, Järvelin AI, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW. (2017)

Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap.

Nat Protoc 12(12):2447-2464. doi: 10.1038/nprot.2017.106
Europe PMC | doi

Quintas A, Pérez-Núñez D, Sánchez EG, Nogal ML, Hentze MW, Castelló A, Revilla Y. (2017)

Characterization of the African swine fever virus decapping enzyme during infection.

J. Virol. 91(24) doi: 10.1128/JVI.00990-17
Europe PMC | doi

Costa da Silva M, Breckwoldt MO, Vinchi F, Correia MP, Stojanovic A, Thielmann CM, Meister M, Muley T, Warth A, Platten M, Hentze MW, Cerwenka A, Muckenthaler MU. (2017)

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages.

Front Immunol 8 doi: 10.3389/fimmu.2017.01479
Europe PMC | doi

Neu-Yilik G, Raimondeau E, Eliseev B, Yeramala L, Amthor B, Deniaud A, Huard K, Kerschgens K, Hentze MW, Schaffitzel C, Kulozik AE. (2017)

Dual function of UPF3B in early and late translation termination.

EMBO J 36(20) doi: 10.15252/embj.201797079
Europe PMC | doi

Haberman N, Huppertz I, Attig J, König J, Wang Z, Hauer C, Hentze MW, Kulozik AE, Le Hir H, Curk T, Sibley CR, Zarnack K, Ule J. (2017)

Erratum to: Insights into the design and interpretation of iCLIP experiments.

Genome Biol 18(1) doi: 10.1186/s13059-017-1294-z
Europe PMC | doi

da Silva AR, Neves J, Mleczko-Sanecka K, Tandon A, Sauer SW, Hentze MW, Muckenthaler MU. (2017)

Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin.

J. Mol. Med. 95(8):851-860. doi: 10.1007/s00109-017-1551-3
Europe PMC | doi

Rogell BM, Fischer B, Rettel M, Krijgsveld J, Castello A, Hentze MW. (2017)

Specific RNP capture with antisense LNA/DNA mixmers.

RNA 23(8) doi: 10.1261/rna.060798.117
Europe PMC | doi

Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, Jordan J, Bauersachs J, Hentze MW, Wollert KC, Kempf T. (2017)

Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.

Eur. Heart J. 38(5):362-372. doi: 10.1093/eurheartj/ehw333
Europe PMC | doi

Muckenthaler MU, Rivella S, Hentze MW, Galy B. (2017)

A Red Carpet for Iron Metabolism.

Cell 168(3):344-361. doi: 10.1016/j.cell.2016.12.034
Europe PMC | doi

Haberman N, Huppertz I, Attig J, König J, Wang Z, Hauer C, Hentze MW, Kulozik AE, Le Hir H, Curk T, Sibley CR, Zarnack K, Ule J. (2017)

Insights into the design and interpretation of iCLIP experiments.

Genome Biol. 18(1):7. doi: 10.1186/s13059-016-1130-x
Europe PMC | doi


Reichel M, Liao Y, Rettel M, Ragan C, Evers M, Alleaume AM, Horos R, Hentze MW, Preiss T, Millar AA. (2016)

In planta determination of the mRNA-binding proteome of Arabidopsis etiolated seedlings.

Plant Cell 28(10) doi: 10.1105/tpc.16.00562
Europe PMC | doi

Castello A, Fischer B, Frese CK, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW. (2016)

Comprehensive Identification of RNA-Binding Domains in Human Cells.

Mol. Cell 63(4):696-710. doi: 10.1016/j.molcel.2016.06.029
Europe PMC | doi

Hauer C, Sieber J, Schwarzl T, Hollerer I, Curk T, Alleaume AM, Hentze MW, Kulozik AE. (2016)

Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins.

Cell Rep 16(6):1588-1603. doi: 10.1016/j.celrep.2016.06.096
Europe PMC | doi

Liepelt A, Naarmann-de Vries IS, Simons N, Eichelbaum K, Foehr S, Archer SK, Castello A, Usadel B, Krijgsveld J, Preiss T, Marx G, Hentze MW, Ostareck DH, Ostareck-Lederer A. (2016)

Identification of RNA-binding proteins in macrophages by interactome capture.

Mol. Cell Proteomics 15(8):2699-2714. doi: 10.1074/mcp.M115.056564
Europe PMC | doi

Liao Y, Castello A, Fischer B, Leicht S, Föehr S, Frese C, Ragan C, Kurscheid S, Pagler E, Yang H, Krijgsveld J, Hentze MW, Preiss T. (2016)

The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease

Cell Rep 16(5):1456-1469. doi: 10.1016/j.celrep.2016.06.084
Europe PMC | doi

Hollerer I, Curk T, Haase B, Benes V, Hauer C, Neu-Yilik G, Bhuvanagiri M, Hentze MW, Kulozik AE. (2016)

The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion.

RNA 22(9):1441-1453. doi: 10.1261/rna.055657.115
Europe PMC | doi

Sysoev VO, Fischer B, Frese CK, Gupta I, Krijgsveld J, Hentze MW, Castello A, Ephrussi A. (2016)

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila.

Nat Commun 7:12128. doi: 10.1038/ncomms12128
Europe PMC | doi

Kovac S, Böser P, Cui Y, Ferring-Appel D, Casarrubea D, Huang L, Fung E, Popp A, Mueller BK, Hentze MW. (2016)

Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels.

Haematologica 101(5):e173-176. doi: 10.3324/haematol.2015.140772
Europe PMC | doi

Sieber J, Hauer C, Bhuvanagiri M, Leicht S, Krijgsveld J, Neu-Yilik G, Hentze MW, Kulozik AE. (2016)

Proteomic analysis reveals branch-specific regulation of the unfolded protein response by nonsense-mediated mRNA decay.

Mol. Cell Proteomics 15(5) doi: 10.1074/mcp.M115.054056
Europe PMC | doi

Theurl M, Song D, Clark E, Sterling J, Grieco S, Altamura S, Galy B, Hentze M, Muckenthaler MU, Dunaief JL. (2016)

Mice with hepcidin-resistant ferroportin accumulate iron in the retina.

FASEB J. 30(2):813-823. doi: 10.1096/fj.15-276758
Europe PMC | doi

Gebauer F, Hentze MW. (2016)

IRES unplugged.

Science 351(6270) doi: 10.1126/science.aad8540
Europe PMC | doi

Castello A, Horos R, Strein C, Fischer B, Eichelbaum K, Steinmetz LM, Krijgsveld J, Hentze MW. (2016)

Comprehensive Identification of RNA-Binding Proteins by RNA Interactome Capture.

Methods Mol. Biol. 1358:131-139. doi: 10.1007/978-1-4939-3067-8_8
Europe PMC | doi


Siegert I, Schödel J, Nairz M, Schatz V, Dettmer K, Dick C, Kalucka J, Franke K, Ehrenschwender M, Schley G, Beneke A, Sutter J, Moll M, Hellerbrand C, Wielockx B, Katschinski DM, Lang R, Galy B, Hentze MW, Koivunen P, Oefner PJ, Bogdan C, Weiss G, Willam C, Jantsch J. (2015)

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.

Cell Rep 13(10):2048-2055. doi: 10.1016/j.celrep.2015.11.005
Europe PMC | doi

Popow J, Alleaume AM, Curk T, Schwarzl T, Sauer S, Hentze MW. (2015)

FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation.

RNA 21(11) doi: 10.1261/rna.052365.115
Europe PMC | doi

Beckmann BM, Horos R, Fischer B, Castello A, Eichelbaum K, Alleaume AM, Schwarzl T, Curk T, Foehr S, Huber W, Krijgsveld J, Hentze MW. (2015)

The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs.

Nat Commun 6 doi: 10.1038/ncomms10127
Europe PMC | doi

Castello A, Hentze MW, Preiss T. (2015)

Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins.

Trends Endocrinol. Metab. 26(12):746-757. doi: 10.1016/j.tem.2015.09.012
Europe PMC | doi

Nairz M, Ferring-Appel D, Casarrubea D, Sonnweber T, Viatte L, Schroll A, Haschka D, Fang FC, Hentze MW, Weiss G, Galy B. (2015)

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

Cell Host Microbe 18(2):254-261. doi: 10.1016/j.chom.2015.06.017
Europe PMC | doi

Hauer C, Curk T, Anders S, Schwarzl T, Alleaume AM, Sieber J, Hollerer I, Bhuvanagiri M, Huber W, Hentze MW, Kulozik AE. (2015)

Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP.

Nat Commun 6:7921. doi: 10.1038/ncomms8921
Europe PMC | doi

Guida C, Altamura S, Klein FA, Galy B, Boutros M, Ulmer AJ, Hentze MW, Muckenthaler MU. (2015)

A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia.

Blood 125(14):2265-2275. doi: 10.1182/blood-2014-08-595256
Europe PMC | doi

Martelli A, Schmucker S, Reutenauer L, Mathieu JR, Peyssonnaux C, Karim Z, Puy H, Galy B, Hentze MW, Puccio H. (2015)

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.

Cell Metab. 21(2):311-322. doi: 10.1016/j.cmet.2015.01.010
Europe PMC | doi


Bhuvanagiri M, Lewis J, Putzker K, Becker JP, Leicht S, Krijgsveld J, Batra R, Turnwald B, Jovanovic B, Hauer C, Sieber J, Hentze MW, Kulozik AE. (2014)

5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.

EMBO Mol Med 6(12):1509-1639. doi: 10.15252/emmm.201404461
Europe PMC | doi

Kramer K, Sachsenberg T, Beckmann BM, Qamar S, Boon KL, Hentze MW, Kohlbacher O, Urlaub H. (2014)

Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins.

Nat. Methods 11(10):1064-1070. doi: 10.1038/nmeth.3092
Europe PMC | doi

Altamura S, Kessler R, Gröne HJ, Gretz N, Hentze MW, Galy B, Muckenthaler MU. (2014)

Resistance of Ferroportin to Hepcidin Binding causes Exocrine Pancreatic Failure and Fatal Iron Overload

Cell Metab. 20(2):359-367. doi: 10.1016/j.cmet.2014.07.007
Europe PMC | doi

Strein C, Alleaume AM, Rothbauer U, Hentze MW, Castello A. (2014)

A versatile assay for RNA-binding proteins in living cells

RNA 20(5):721-731. doi: 10.1261/rna.043562.113
Europe PMC | doi

Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, Wittig JG, Chen W, Lu W, Galy B, Schlaeger TM, Hentze MW, Ward DM, Kaplan J, Eisenstein RS, Peters LL, Paw BH. (2014)

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria

J. Biol. Chem. 289(11):7835-7843. doi: 10.1074/jbc.m114.547778
Europe PMC | doi

Mleczko-Sanecka K, Roche F, da Silva AR, Call D, D'Alessio F, Ragab A, Lapinski PE, Ummanni R, Korf U, Oakes C, Damm G, D'Alessandro LA, Klingmüller U, King PD, Boutros M, Hentze MW, Muckenthaler MU. (2014)

Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.

Blood 123(10):1574-1585. doi: 10.1182/blood-2013-07-515957
Europe PMC | doi

Hollerer I, Grund K, Hentze MW, Kulozik AE. (2014)

mRNA 3'end processing: A tale of the tail reaches the clinic

EMBO Mol Med 6(1):16-26. doi: 10.1002/emmm.201303300
Europe PMC | doi


Altamura S, Grone HJ, Kessler R, Galy B, Hentze MW, Muckenthaler MU. (2013)

In Vivo Disruption Of The Hepcidin-Ferroportin Regulatory Circuitry Causes Fatal Systemic and Exocrine Pancreatic Iron Overload

BLOOD 122(21) doi: 10.1182/blood.V122.21.175.175

Danckwardt S, Hentze MW, Kulozik AE. (2013)

Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond

J. Mol. Med. 91(11):1257-1271. doi: 10.1007/s00109-013-1074-5
Europe PMC | doi

Kwon SC, Yi H, Eichelbaum K, Föhr S, Fischer B, You KT, Castello A, Krijgsveld J, Hentze MW, Kim VN. (2013)

The RNA-binding protein repertoire of embryonic stem cells

Nat. Struct. Mol. Biol. 20(9):1122-1130. doi: 10.1038/nsmb.2638
Europe PMC | doi

Casarrubea D, Viatte L, Hallas T, Vasanthakumar A, Eisenstein RS, Schümann K, Hentze MW, Galy B. (2013)

Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function

J. Mol. Med. 91(7):871-881. doi: 10.1007/s00109-013-1008-2
Europe PMC | doi

Hentze MW, Izaurralde E. (2013)

Making sense of nonsense

Nat. Struct. Mol. Biol. 20(6):651-653. doi: 10.1038/nsmb.2601
Europe PMC | doi

Castello A, Fischer B, Hentze MW, Preiss T. (2013)

RNA-binding proteins in Mendelian disease

Trends Genet. 29(5):318-327. doi: 10.1016/j.tig.2013.01.004
Europe PMC | doi

Galy B, Ferring-Appel D, Becker C, Gretz N, Grone HJ, Schumann K, Hentze MW. (2013)


AM J HEMATOL 88(5):E28.

Guida C, Altamura S, Klein F, Boutros M, Hentze MW, Martina UM. (2013)


AM J HEMATOL 88(5):E128-E129.

Nairz M, Ferring-Appel D, Schroll A, Hentze MW, Weiss G, Galy B. (2013)


AM J HEMATOL 88(5):E26.

Hentze MW, Preiss T. (2013)

Circular RNAs: splicing's enigma variations

EMBO J. 32(7):923-925. doi: 10.1038/emboj.2013.53
Europe PMC | doi

Castello A, Horos R, Strein C, Fischer B, Eichelbaum K, Steinmetz LM, Krijgsveld J, Hentze MW. (2013)

System-wide identification of RNA-binding proteins by interactome capture

Nat Protoc 8(3):491-500. doi: 10.1038/nprot.2013.020
Europe PMC | doi

Galy B, Ferring-Appel D, Becker C, Gretz N, Gröne HJ, Schümann K, Hentze MW. (2013)

Iron regulatory proteins control a mucosal block to intestinal iron absorption

Cell Rep 3(3):844-857. doi: 10.1016/j.celrep.2013.02.026
Europe PMC | doi

Anderson SA, Nizzi CP, Chang YI, Deck KM, Schmidt PJ, Galy B, Damnernsawad A, Broman AT, Kendziorski C, Hentze MW, Fleming MD, Zhang J, Eisenstein RS. (2013)

The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption

Cell Metab. 17(2):282-290. doi: 10.1016/j.cmet.2013.01.007
Europe PMC | doi


D'Alessio F, Hentze MW, Muckenthaler MU. (2012)

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

J. Hepatol. 57(5):1052-1060. doi: 10.1016/j.jhep.2012.06.015
Europe PMC | doi

Casanova CM, Sehr P, Putzker K, Hentze MW, Neumann B, Duncan KE, Thoma C. (2012)

Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation

PLoS ONE 7(9):e45943. doi: 10.1371/journal.pone.0045943
Europe PMC | doi

Gebauer F, Preiss T, Hentze MW. (2012)

From cis-regulatory elements to complex RNPs and back

Cold Spring Harb Perspect Biol 4(7):a012245. doi: 10.1101/cshperspect.a012245
Europe PMC | doi

Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW. (2012)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

Cell 149(6):1393-1406. doi: 10.1016/j.cell.2012.04.031
Europe PMC | doi

Moretti F, Kaiser C, Zdanowicz-Specht A, Hentze MW. (2012)

PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding

Nat. Struct. Mol. Biol. 19(6):603-608. doi: 10.1038/nsmb.2309
Europe PMC | doi


Sanchez M, Galy B, Schwanhaeusser B, Blake J, Bähr-Ivacevic T, Benes V, Selbach M, Muckenthaler MU, Hentze MW. (2011)

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins

Blood 118(22):e168-79. doi: 10.1182/blood-2011-04-343541
Europe PMC | doi

Medenbach J, Seiler M, Hentze MW. (2011)

Translational control via protein-regulated upstream open reading frames

Cell 145(6):902-913. doi: 10.1016/j.cell.2011.05.005
Europe PMC | doi

Neu-Yilik G, Amthor B, Gehring NH, Bahri S, Paidassi H, Hentze MW, Kulozik AE. (2011)

Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon

RNA 17(5):843-854. doi: 10.1261/rna.2401811
Europe PMC | doi

Rakotondrafara AM, Hentze MW. (2011)

An efficient factor-depleted mammalian in vitro translation system

Nat Protoc 6(5):563-571. doi: 10.1038/nprot.2011.314
Europe PMC | doi

Castoldi M, Vujic Spasic M, Altamura S, Elmén J, Lindow M, Kiss J, Stolte J, Sparla R, D'Alessandro LA, Klingmüller U, Fleming RE, Longerich T, Gröne HJ, Benes V, Kauppinen S, Hentze MW, Muckenthaler MU. (2011)

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

J. Clin. Invest. 121(4):1386-1396. doi: 10.1172/jci44883
Europe PMC | doi

Danckwardt S, Gantzert AS, Macher-Goeppinger S, Probst HC, Gentzel M, Wilm M, Gröne HJ, Schirmacher P, Hentze MW, Kulozik AE. (2011)

p38 MAPK controls prothrombin expression by regulated RNA 3' end processing

Mol. Cell 41(3):298-310. doi: 10.1016/j.molcel.2010.12.032
Europe PMC | doi


Moretti F, Thermann R, Hentze MW. (2010)

Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame

RNA 16(12):2493-2502. doi: 10.1261/rna.2384610
Europe PMC | doi

Bhuvanagiri M, Schlitter AM, Hentze MW, Kulozik AE. (2010)

NMD: RNA biology meets human genetic medicine

Biochem. J. 430(3):365-377. doi: 10.1042/bj20100699
Europe PMC | doi

Cohen LA, Gutierrez L, Weiss A, Leichtmann-Bardoogo Y, Zhang DL, Crooks DR, Sougrat R, Morgenstern A, Galy B, Hentze MW, Lazaro FJ, Rouault TA, Meyron-Holtz EG. (2010)

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway

Blood 116(9):1574-1584. doi: 10.1182/blood-2009-11-253815
Europe PMC | doi

Galy B, Ferring-Appel D, Sauer SW, Kaden S, Lyoumi S, Puy H, Kölker S, Gröne HJ, Hentze MW. (2010)

Iron regulatory proteins secure mitochondrial iron sufficiency and function

Cell Metab. 12(2):194-201. doi: 10.1016/j.cmet.2010.06.007
Europe PMC | doi

Hentze MW, Preiss T. (2010)

The REM phase of gene regulation

Trends Biochem. Sci. 35(8):423-426. doi: 10.1016/j.tibs.2010.05.009
Europe PMC | doi

Campillos M, Cases I, Hentze MW, Sanchez M. (2010)

SIREs: searching for iron-responsive elements

Nucleic Acids Res. 38(Web Server issue):W360-7. doi: 10.1093/nar/gkq371
Europe PMC | doi

Hentze MW, Muckenthaler MU, Galy B, Camaschella C. (2010)

Two to tango: regulation of Mammalian iron metabolism

Cell 142(1):24-38. doi: 10.1016/j.cell.2010.06.028
Europe PMC | doi

Mleczko-Sanecka K, Casanovas G, Ragab A, Breitkopf K, Müller A, Boutros M, Dooley S, Hentze MW, Muckenthaler MU. (2010)

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

Blood 115(13):2657-2665. doi: 10.1182/blood-2009-09-238105
Europe PMC | doi

Lopes TJ, Luganskaja T, Vujić Spasić M, Hentze MW, Muckenthaler MU, Schümann K, Reich JG. (2010)

Systems analysis of iron metabolism: the network of iron pools and fluxes

BMC Syst Biol 4:112. doi: 10.1186/1752-0509-4-112
Europe PMC | doi

Pisarev AV, Skabkin MA, Pisareva VP, Skabkina OV, Rakotondrafara AM, Hentze MW, Hellen CU, Pestova TV. (2010)

The role of ABCE1 in eukaryotic posttermination ribosomal recycling

Mol. Cell 37(2):196-210. doi: 10.1016/j.molcel.2009.12.034
Europe PMC | doi

Vainshtein Y, Sanchez M, Brazma A, Hentze MW, Dandekar T, Muckenthaler MU. (2010)

The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays

BMC Bioinformatics 11:112. doi: 10.1186/1471-2105-11-112
Europe PMC | doi


Duncan KE, Strein C, Hentze MW. (2009)

The SXL-UNR corepressor complex uses a PABP-mediated mechanism to inhibit ribosome recruitment to msl-2 mRNA

Mol. Cell 36(4):571-582. doi: 10.1016/j.molcel.2009.09.042
Europe PMC | doi

Viatte L, Gröne HJ, Hentze MW, Galy B. (2009)

In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation

J. Mol. Med. 87(9):913-921. doi: 10.1007/s00109-009-0494-8
Europe PMC | doi

Zdanowicz A, Thermann R, Kowalska J, Jemielity J, Duncan K, Preiss T, Darzynkiewicz E, Hentze MW. (2009)

Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression

Mol. Cell 35(6):881-888. doi: 10.1016/j.molcel.2009.09.009
Europe PMC | doi

Clerici M, Mourão A, Gutsche I, Gehring NH, Hentze MW, Kulozik A, Kadlec J, Sattler M, Cusack S. (2009)

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

EMBO J. 28(15):2293-2306. doi: 10.1038/emboj.2009.175
Europe PMC | doi

Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU. (2009)

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD

J. Mol. Med. 87(5):471-480. doi: 10.1007/s00109-009-0447-2
Europe PMC | doi

Gehring NH, Lamprinaki S, Hentze MW, Kulozik AE. (2009)

The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay

PLoS Biol. 7(5):e1000120. doi: 10.1371/journal.pbio.1000120
Europe PMC | doi

Gehring NH, Lamprinaki S, Kulozik AE, Hentze MW. (2009)

Disassembly of exon junction complexes by PYM

Cell 137(3):536-548. doi: 10.1016/j.cell.2009.02.042
Europe PMC | doi

Hentze MW. (2009)

EMBO Molecular Medicine: Conquering new frontiers

EMBO Mol Med 1(1):5. doi: 10.1002/emmm.200900011
Europe PMC | doi

Beilharz TH, Humphreys DT, Clancy JL, Thermann R, Martin DI, Hentze MW, Preiss T. (2009)

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells

PLoS ONE 4(8) doi: 10.1371/journal.pone.0006783
Europe PMC | doi

Ferring-Appel D, Hentze MW, Galy B. (2009)

Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism

Blood 113(3):679-687. doi: 10.1182/blood-2008-05-155093
Europe PMC | doi


Thoma C, Fraterman S, Gentzel M, Wilm M, Hentze MW. (2008)

Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail

RNA 14(8):1579-1589. doi: 10.1261/rna.1043908
Europe PMC | doi

Verga Falzacappa MV, Casanovas G, Hentze MW, Muckenthaler MU. (2008)

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

J. Mol. Med. 86(5):531-540. doi: 10.1007/s00109-008-0313-7
Europe PMC | doi