Total: 36 publication(s)


Sonnen KF, Merten CA. (2019)

Microfluidics as an emerging precision tool in developmental biology.

Dev. Cell 48(3):293-311. doi: 10.1016/j.devcel.2019.01.015
Europe PMC | doi

Hildebrand F, Moitinho-Silva L, Blasche S, Jahn MTT, Gossmann TI, Huerta Cepas J, Hercog R, Luetge M, Bahram M, Pryszlak A, Alves RJ, Waszak SM, Zhu A, Ye L, Costea PI, Belzer C, Aalvink S, Sunagawa S, Forslund SK, Merten C, Hentschel U, Benes V, Patil KR, Bork P. (2019)

Antibiotics-induced monodominance of a novel gut bacterial order.

Gut 68(10):1781-1790. doi: 10.1136/gutjnl-2018-317715
Europe PMC | doi


Eduati F, Utharala R, Madhavan D, Neumann UP, Longerich T, Cramer T, Saez-Rodriguez J, Merten CA. (2018)

A microfluidics platform for combinatorial drug screening on cancer biopsies.

Nat Commun 9(1) doi: 10.1038/s41467-018-04919-w
Europe PMC | doi

Utharala R, Tseng Q, Furlong EEM, Merten CA. (2018)

A versatile, low-cost, multiway microfluidic sorter for droplets, cells, and embryos.

Anal Chem 90(10):5982-5988. doi: 10.1021/acs.analchem.7b04689
Europe PMC | doi

Sonnen KF, Lauschke VM, Uraji J, Falk HJ, Petersen Y, Funk MC, Beaupeux M, François P, Merten CA, Aulehla A. (2018)

Modulation of phase shift between wnt and notch signaling oscillations controls mesoderm segmentation.

Cell 172(5):1079-1090.e12. doi: 10.1016/j.cell.2018.01.026
Europe PMC | doi

Shembekar N, Hu H, Eustace D, Merten CA. (2018)

Single-cell droplet microfluidic screening for antibodies specifically binding to target cells.

Cell Rep 22(8):2206-2215. doi: 10.1016/j.celrep.2018.01.071
Europe PMC | doi

Seah YFS, Hu H, Merten CA. (2018)

Microfluidic single-cell technology in immunology and antibody screening.

Mol. Aspects Med. 59 doi: 10.1016/j.mam.2017.09.004
Europe PMC | doi


Chaipan C, Pryszlak A, Dean H, Poignard P, Benes V, Griffiths AD, Merten CA. (2017)

Single-virus droplet microfluidics for high-throughput screening of neutralizing epitopes on HIV particles.

Cell Chem Biol 24(6):751-757. doi: 10.1016/j.chembiol.2017.05.009
Europe PMC | doi

Frenzel D, Merten CA. (2017)

Microfluidic train station: highly robust and multiplexable sorting of droplets on electric rails.

Lab Chip 17(6):1024-1030. doi: 10.1039/c6lc01544a
Europe PMC | doi


Shembekar N, Chaipan C, Utharala R, Merten CA. (2016)

Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics.

Lab Chip 16(8):1314-1331. doi: 10.1039/c6lc00249h
Europe PMC | doi


Ramanathan N, Simakov O, Merten CA, Arendt D. (2015)

Quantifying preferences and responsiveness of marine zooplankton to changing environmental conditions using microfluidics.

PLoS ONE 10(10) doi: 10.1371/journal.pone.0140553
Europe PMC | doi

Hu H, Eustace D, Merten CA. (2015)

Efficient cell pairing in droplets using dual-color sorting.

Lab Chip 15(20):3989-3993. doi: 10.1039/c5lc00686d
Europe PMC | doi

Hara Y, Merten CA. (2015)

Dynein-based accumulation of membranes regulates nuclear expansion in xenopus laevis egg extracts.

Dev. Cell 33(5) doi: 10.1016/j.devcel.2015.04.016
Europe PMC | doi

Eicher D, Ramanathan N, Merten CA. (2015)

Soft compartmentalization: Combining droplet-based microfluidics with freely accessible cells

Eng. Life Sci. 15(3):297-305. doi: 10.1002/elsc.201400184


El Debs B, Utharala R, Merten CA. (2014)

Screening cellular metabolic activity.

Nat. Biotechnol. 32(11) doi: 10.1038/nbt.3058
Europe PMC | doi


Tseng Q, Lomonosov AM, Furlong EE, Merten CA. (2012)

Fragmentation of DNA in a sub-microliter microfluidic sonication device

Lab Chip 12(22):4677-4682. doi: 10.1039/c2lc40595d
Europe PMC | doi

El Debs B, Utharala R, Balyasnikova IV, Griffiths AD, Merten CA. (2012)

Functional single-cell hybridoma screening using droplet-based microfluidics

Proc. Natl. Acad. Sci. U.S.A. 109(29):11570-11575. doi: 10.1073/pnas.1204514109
Europe PMC | doi

Clausell-Tormos J, Merten CA. (2012)

Micro segmented-flow in biochemical and cell-based assays

Front Biosci (Elite Ed) 4:1768-1779. doi: 10.2741/497
Europe PMC | doi


El Debs BW, Tschulena U, Griffiths AD, Merten CA. (2011)

A competitive co-cultivation assay for cancer drug specificity evaluation

J Biomol Screen 16(8):818-824. doi: 10.1177/1087057111414898
Europe PMC | doi

Eicher D, Merten CA. (2011)

Microfluidic devices for diagnostic applications

Expert Rev. Mol. Diagn. 11(5):505-519. doi: 10.1586/erm.11.25
Europe PMC | doi

Urban JH, Merten CA. (2011)

Retroviral display in gene therapy, protein engineering, and vaccine development

ACS Chem. Biol. 6(1):61-74. doi: 10.1021/cb100285n
Europe PMC | doi


Vyawahare S, Griffiths AD, Merten CA. (2010)

Miniaturization and parallelization of biological and chemical assays in microfluidic devices

Chem. Biol. 17(10):1052-1065. doi: 10.1016/j.chembiol.2010.09.007
Europe PMC | doi

Merten CA. (2010)

Screening Europe 2010: an update about the latest technologies and applications in high-throughput screening

Expert Rev. Mol. Diagn. 10(5):559-563. doi: 10.1586/erm.10.42
Europe PMC | doi

Clausell-Tormos J, Griffiths AD, Merten CA. (2010)

An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries

Lab Chip 10(10):1302-1307. doi: 10.1039/b921754a
Europe PMC | doi

Clausell-Tormos J, Griffiths AD, Merten CA. (2010)

Coupling the inhibition of viral transduction with a positive fluorescence signal

Comb. Chem. High Throughput Screen. 13(4):352-357. doi: 10.2174/138620710791054312
Europe PMC | doi

Upert G, Merten CA, Wennemers H. (2010)

Nanoliter plates--versatile tools for the screening of split-and-mix libraries on-bead and off-bead

Chem. Commun. (Camb.) 46(13):2209-2211. doi: 10.1039/b927017e
Europe PMC | doi

Granieri L, Baret JC, Griffiths AD, Merten CA. (2010)

High-throughput screening of enzymes by retroviral display using droplet-based microfluidics

Chem. Biol. 17(3):229-235. doi: 10.1016/j.chembiol.2010.02.011
Europe PMC | doi


Granieri L, Miller OJ, Griffiths AD, Merten CA. (2009)

A competition-based assay for the screening of species-specific antibiotics

J. Antimicrob. Chemother. 64(1):62-68. doi: 10.1093/jac/dkp137
Europe PMC | doi

Pianowski Z, Gorska K, Oswald L, Merten CA, Winssinger N. (2009)

Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes

J. Am. Chem. Soc. 131(18):6492-6497. doi: 10.1021/ja809656k
Europe PMC | doi

Baret JC, Taly V, Ryckelynck M, Merten CA, Griffiths AD. (2009)

[Droplets and emulsions: very high-throughput screening in biology]

Med Sci (Paris) 25(6-7):627-632. doi: 10.1051/medsci/2009256-7627
Europe PMC | doi


Köster S, Angilè FE, Duan H, Agresti JJ, Wintner A, Schmitz C, Rowat AC, Merten CA, Pisignano D, Griffiths AD, Weitz DA. (2008)

Drop-based microfluidic devices for encapsulation of single cells

Lab Chip 8(7):1110-1115. doi: 10.1039/b802941e
Europe PMC | doi

Clausell-Tormos J, Lieber D, Baret JC, El-Harrak A, Miller OJ, Frenz L, Blouwolff J, Humphry KJ, Köster S, Duan H, Holtze C, Weitz DA, Griffiths AD, Merten CA. (2008)

Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms

Chem. Biol. 15(5):427-437. doi: 10.1016/j.chembiol.2008.04.004
Europe PMC | doi


Merten CA, Stitz J, Braun G, Medvedovska J, Cichutek K, Buchholz CJ. (2006)

Fusoselect: cell-cell fusion activity engineered by directed evolution of a retroviral glycoprotein

Nucleic Acids Res. 34(5):e41. doi: 10.1093/nar/gkl053
Europe PMC | doi


Nikles D, Bach P, Boller K, Merten CA, Montrasio F, Heppner FL, Aguzzi A, Cichutek K, Kalinke U, Buchholz CJ. (2005)

Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP

J. Virol. 79(7):4033-4042. doi: 10.1128/jvi.79.7.4033-4042.2005
Europe PMC | doi

Merten CA, Stitz J, Braun G, Poeschla EM, Cichutek K, Buchholz CJ. (2005)

Directed evolution of retrovirus envelope protein cytoplasmic tails guided by functional incorporation into lentivirus particles

J. Virol. 79(2):834-840. doi: 10.1128/jvi.79.2.834-840.2005
Europe PMC | doi


Merten CA, Engelstaedter M, Buchholz CJ, Cichutek K. (2003)

Displaying epidermal growth factor on spleen necrosis virus-derived targeting vectors

Virology 305(1):106-114. doi: 10.1006/viro.2002.1778
Europe PMC | doi