EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Phone: +49 6221 387 8964

ORCID iD: iD icon0000-0002-9457-4130

Publications

Total: 12 publication(s)

2019

Volkwein W, Krafczyk R, Jagtap PKA, Parr M, Mankina E, Macosek J, Guo Z, Fürst M, Pfab M, Frishman D, Hennig J, Jung K, Lassak J. (2019)

Switching the Post-translational Modification of Translation Elongation Factor EF-P

Front Microbiol doi: 10.3389/fmicb.2019.01148
Europe PMC | doi

Pravin Kumar Ankush Jagtap, Marisa Müller, Pawel Masiewicz, Sören von Bülow, Nele Merret Hollmann, Po-Chia Chen, Bernd Simon, Andreas W Thomae, Peter B Becker, Janosch Hennig. (2019)

Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless

Nucleic Acids Res. doi: 10.1093/nar/gkz125
Europe PMC | doi

Pravin Kumar Ankush Jagtap, Sam Asami, Claudia Sippel, Ville Kaila, Felix Hausch, Michael Sattler. (2019)

Selective inhibitors of FKBP51 employ conformational selection of dynamic invisible states

Angew. Chem. Int. Ed. Engl. doi: 10.1002/anie.201902994
Europe PMC | doi


2018

Vithani N, Jagtap PKA, Verma SK, Tripathi R, Awasthi S, Nair NN, Prakash B. (2018)

Mechanism of Mg 2+ -Accompanied Product Release in Sugar Nucleotidyltransferases

Structure 26(3) doi: 10.1016/j.str.2018.02.002
Europe PMC | doi


2017

Krafczyk R, Macošek J, Jagtap PKA, Gast D, Wunder S, Mitra P, Jha AK, Rohr J, Hoffmann-Röder A, Jung K, Hennig J, Lassak J. (2017)

Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P.

MBio 8(5) doi: 10.1128/mBio.01412-17
Europe PMC | doi

Sonntag M, Jagtap PKA, Simon B, Appavou MS, Geerlof A, Stehle R, Gabel F, Hennig J, Sattler M. (2017)

Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins.

Angew Chem Int Ed Engl 56(32):9322-9325. doi: 10.1002/anie.201702904
Europe PMC | doi


2016

Jagtap PK, Garg D, Kapp TG, Will CL, Demmer O, Lührmann R, Kessler H, Sattler M. (2016)

Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.

J Med Chem 59(22):10190-10197. doi: 10.1021/acs.jmedchem.6b01118
Europe PMC | doi

Guaitoli G, Raimondi F, Gilsbach BK, Gómez-Llorente Y, Deyaert E, Renzi F, Li X, Schaffner A, Jagtap PK, Boldt K, von Zweydorf F, Gotthardt K, Lorimer DD, Yue Z, Burgin A, Janjic N, Sattler M, Versées W, Ueffing M, Ubarretxena-Belandia I, Kortholt A, Gloeckner CJ. (2016)

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.

Proc Natl Acad Sci U S A 113(30):E4357-66. doi: 10.1073/pnas.1523708113
Europe PMC | doi


2014

Piccoli G, Onofri F, Cirnaru MD, Kaiser CJ, Jagtap P, Kastenmüller A, Pischedda F, Marte A, von Zweydorf F, Vogt A, Giesert F, Pan L, Antonucci F, Kiel C, Zhang M, Weinkauf S, Sattler M, Sala C, Matteoli M, Ueffing M, Gloeckner CJ. (2014)

Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain.

Mol Cell Biol 34(12):2147-61. doi: 10.1128/MCB.00914-13
Europe PMC | doi

Wang I, Hennig J, Jagtap PK, Sonntag M, Valcárcel J, Sattler M. (2014)

Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.

Nucleic Acids Res. 42(9):5949-5966. doi: 10.1093/nar/gku193
Europe PMC | doi


2013

Jagtap PK, Verma SK, Vithani N, Bais VS, Prakash B. (2013)

Crystal structures identify an atypical two-metal-ion mechanism for uridyltransfer in GlmU: its significance to sugar nucleotidyl transferases.

J Mol Biol 425(10):1745-59. doi: 10.1016/j.jmb.2013.02.019
Europe PMC | doi


2012

Jagtap PK, Soni V, Vithani N, Jhingan GD, Bais VS, Nandicoori VK, Prakash B. (2012)

Substrate-bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine 1-phosphate uridyltransferase and a catalytic mechanism for acetyl transfer.

J Biol Chem 287(47):39524-37. doi: 10.1074/jbc.M112.390765
Europe PMC | doi