EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
PhD 1984, Cambridge University.
Postdoctoral research at the Laboratory of Molecular Biology, Cambridge.
At EMBL since 1986.
Team leader at EMBL since 1996.
Total: 153 publication(s)
Gibson TJ, Ramu C, Gemünd C, Aasland R. (1998)
The APECED polyglandular autoimmune syndrome protein, AIRE-1, contains the SAND domain and is probably a transcription factor
Gibson TJ, Spring J. (1998)
Genetic redundancy in vertebrates: polyploidy and persistence of genes encoding multidomain proteins
Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. (1997)
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools
Musco G, Kharrat A, Stier G, Fraternali F, Gibson TJ, Nilges M, Pastore A. (1997)
The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome
Gibson TJ, Koonin EV, Musco G, Pastore A, Bork P. (1996)
Friedreich's ataxia protein: phylogenetic evidence for mitochondrial dysfunction
Birney E, Thompson JD, Gibson TJ. (1996)
PairWise and SearchWise: finding the optimal alignment in a simultaneous comparison of a protein profile against all DNA translation frames
Musco G, Stier G, Joseph C, Castiglione Morelli MA, Nilges M, Gibson TJ, Pastore A. (1996)
Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome.
Aasland R, Stewart AF, Gibson T. (1996)
The SANT domain: A putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional corepressor N-CoR and TFIIIB
Bork P, Gibson TJ. (1996)
Applying motif and profile searches
Higgins DG, Thompson JD, Gibson TJ. (1996)
Using CLUSTAL for multiple sequence alignments
Method Enzymol 266:383-402.
Winder SJ, Gibson TJ, Kendrick-Jones J. (1995)
Dystrophin and utrophin: the missing links!
Kharrat A, Macias MJ, Gibson TJ, Nilges M, Pastore A. (1995)
Structure of the dsRNA binding domain of E. coli RNase III.
Aasland R, Gibson TJ, Stewart AF. (1995)
The PHD finger: implications for chromatin-mediated transcriptional regulation.
Castiglone Morelli MA, Stier G, Gibson T, Joseph C, Musco G, Pastore A, Travè G. (1995)
The KH module has an alpha beta fold.
Thompson JD, Higgins DG, Gibson TJ. (1994)
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
Muhle-Goll C, Gibson T, Schuck P, Schubert D, Nalis D, Nilges M, Pastore A. (1994)
The dimerization stability of the HLH-LZ transcription protein family is modulated by the leucine zippers: a CD and NMR study of TFEB and c-Myc.
Gibson TJ, Hyvönen M, Musacchio A, Saraste M, Birney E. (1994)
PH domain: the first anniversary.
Gibson TJ, Thompson JD. (1994)
Detection of dsRNA-binding domains in RNA helicase A and Drosophila maleless: implications for monomeric RNA helicases.
Higgins DG, Labeit S, Gautel M, Gibson TJ. (1994)
The evolution of titin and related giant muscle proteins.
Gibson TJ, Thompson JD, Blocker A, Kouzarides T. (1994)
Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107.
Thompson JD, Higgins DG, Gibson TJ. (1994)
Improved sensitivity of profile searches through the use of sequence weights and gap excision.
Comput Appl Biosci 10(1):19-29.
Gibson TJ, Higgins DG. (1993)
Non-muscle and smooth muscle myosin light chain kinases: no end in sight.
DNA Seq 3(5):333-5.
Gibson TJ, Rice PM, Thompson JD, Heringa J. (1993)
KH domains within the FMR1 sequence suggest that fragile X syndrome stems from a defect in RNA metabolism.
Musacchio A, Gibson T, Rice P, Thompson J, Saraste M. (1993)
The PH domain: a common piece in the structural patchwork of signalling proteins.
Gibson TJ, Thompson JD, Heringa J. (1993)
The KH domain occurs in a diverse set of RNA-binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid.
Gibson TJ, Thompson JD, Abagyan RA. (1993)
Proposed structure for the DNA-binding domain of the helix-loop-helix family of eukaryotic gene regulatory proteins.
Frampton J, Gibson T, Lim F, McNagny K, Metz T, Ness S, Graf T. (1992)
Mechanisms for the transformation of myeloid and erythroid cells by the nuclear oncogene V-myb.
Leukemia 6 Suppl 3:126S-129S.
Nardelli J, Gibson T, Charnay P. (1992)
Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis
Musacchio A, Gibson T, Lehto VP, Saraste M. (1992)
SH3--an abundant protein domain in search of a function.
Gibson TJ. (1992)
Assignment of α-Helices in Multiply Aligned Protein Sequences — Applications to DNA Binding Motifs
In: Taylor W, Patterns in Protein Sequence and Structure. Springer Verlag.
Frampton J, Gibson TJ, Ness SA, Döderlein G, Graf T. (1991)
Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis.
Gibson TJ, Sibbald PR, Rice P. (1991)
DNA Seq 1(3):213-5.
Saudek V, Pastore A, Morelli MA, Frank R, Gausepohl H, Gibson T. (1991)
The solution structure of a leucine-zipper motif peptide
Labeit S, Gibson T, Lakey A, Leonard K, Zeviani M, Knight P, Wardale J, Trinick J. (1991)
Evidence that nebulin is a protein-ruler in muscle thin filaments.
Saudek V, Pasley HS, Gibson T, Gausepohl H, Frank R, Pastore A. (1991)
Solution structure of the basic region from the transcriptional activator GCN4
Nardelli J, Gibson TJ, Vesque C, Charnay P. (1991)
Base sequence discrimination by zinc-finger DNA-binding domains
Saudek V, Pastore A, Castiglione Morelli MA, Frank R, Gausepohl H, Gibson T, Weih F, Roesch P. (1990)
Solution structure of the DNA-binding domain of the yeast transcriptional activator protein GCN4
Lamond AI, Gibson TJ. (1990)
Catalytic RNA and the origin of genetic systems.
Labeit S, Barlow DP, Gautel M, Gibson T, Holt J, Hsieh CL, Francke U, Leonard K, Wardale J, Whiting A. (1990)
A regular pattern of two types of 100-residue motif in the sequence of titin
Gibson TJ, Argos P. (1990)
Protruding domain of tomato bushy stunt virus coat protein is a hitherto unrecognized class of jellyroll conformation.
Gibson TJ, Lamond AI. (1990)
Metabolic complexity in the RNA world and implications for the origin of protein synthesis
Frampton J, Leutz A, Gibson TJ, Graf T. (1989)
DNA-binding domain ancestry
Campbell JI, Scahill S, Gibson T, Ambler RP. (1989)
The phototrophic bacterium Rhodopseudomonas capsulata sp108 encodes an indigenous class A beta-lactamase.
Gibson TJ, Postma JP, Brown RS, Argos P. (1988)
A model for the tertiary structure of the 28 residue DNA-binding motif ('zinc finger') common to many eukaryotic transcriptional regulatory proteins.
Gibson TJ, Coulson AR, Sulston JE, Little PF. (1987)
Lorist2, a cosmid with transcriptional terminators insulating vector genes from interference by promoters within the insert: effect on DNA yield and cloned insert frequency.
Gibson TJ, Rosenthal A, Waterston RH. (1987)
Lorist6, a cosmid vector with BamHI, NotI, ScaI and HindIII cloning sites and altered neomycin phosphotransferase gene expression.
Gibson TJ, Barrell BG, Farrell PJ. (1986)
Coding content and expression of the EBV B95-8 genome in the region from base 62,248 to base 82,920.
Hudson GS, Gibson TJ, Barrell BG. (1985)
The BamHI F region of the B95-8 Epstein-Barr virus genome.
Wetsel RA, Lundwall A, Davidson F, Gibson T, Tack BF, Fey GH. (1984)
Structure of murine complement component C3. II. Nucleotide sequence of cloned complementary DNA coding for the alpha chain.
J Biol Chem 259(22):13857-62.
Gibson T, Stockwell P, Ginsburg M, Barrell B. (1984)
Homology between two EBV early genes and HSV ribonucleotide reductase and 38K genes.
Biggin MD, Gibson TJ, Hong GF. (1983)
Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.
Baer R, Bankier AT, Biggin MD, Deininger PL, Farrell PJ, Gibson TJ, Hatfull G, Hudson GS, Satchwell SC, Séguin C. (1900)
DNA sequence and expression of the B95-8 Epstein-Barr virus genome.
Gibson TJ, Sulston JE. (1900)
Preparation of large numbers of plasmid DNA samples in microtiter plates by the alkaline lysis method.