EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany


Total: 9 publication(s)


Fromm SA, Lawrence RE, Hurley JH. (2020)

Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9.

Nat Struct Mol Biol 27(11) doi: 10.1038/s41594-020-0490-9
Europe PMC | doi

Su M, Fromm SA, Zoncu R, Hurley JH. (2020)

Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD.

Nature 585(7824) doi: 10.1038/s41586-020-2633-x
Europe PMC | doi


Lawrence RE, Fromm SA, Fu Y, Yokom AL, Kim DJ, Thelen AM, Young LN, Lim C, Samelson AJ, Hurley JH, Zoncu R. (2019)

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.

Science 366(6468) doi: 10.1126/science.aax0364
Europe PMC | doi


Sachse C, Fromm SA. (2018)

Journal of structural biology - paper of the year 2018.

J STRUCT BIOL 204(3):369-370. doi: 10.1016/j.jsb.2018.11.002


Fromm SA, Sachse C. (2016)

Cryo-EM structure determination using segmented helical image reconstruction.

Meth. Enzymol. 579:307-328. doi: 10.1016/bs.mie.2016.05.034
Europe PMC | doi


Fromm SA, Bharat TA, Jakobi AJ, Hagen WJ, Sachse C. (2015)

Seeing tobacco mosaic virus through direct electron detectors.

J. Struct. Biol. 189(2):87-97. doi: 10.1016/j.jsb.2014.12.002
Europe PMC | doi


Fromm SA, Kamenz J, Nöldeke ER, Neu A, Zocher G, Sprangers R. (2014)

In vitro reconstitution of a cellular phase-transition process that involves the mRNA decapping machinery.

Angew. Chem. Int. Ed. Engl. 53(28):7354-7359. doi: 10.1002/anie.201402885
Europe PMC | doi


Audin MJ, Dorn G, Fromm SA, Reiss K, Schütz S, Vorländer MK, Sprangers R. (2013)

The archaeal exosome: identification and quantification of site-specific motions that correlate with cap and RNA binding.

Angew. Chem. Int. Ed. Engl. 52(32):8312-8316. doi: 10.1002/anie.201302811
Europe PMC | doi


Fromm SA, Truffault V, Kamenz J, Braun JE, Hoffmann NA, Izaurralde E, Sprangers R. (2012)

The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex.

EMBO J. 31(2):279-290. doi: 10.1038/emboj.2011.408
Europe PMC | doi