EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Biography

  • PhD 1990, University of Leipzig.
    Habilitation 1995, Humboldt University, Berlin.
    At EMBL since 1991. Head of Unit since 2001.
    Strategic Head of Bioinformatics at EMBL Heidelberg since 2011.
    Group leader in the Molecular Medicine Partnership Unit.
    ERC Advanced Investigator.

Publications

Total: 524 publication(s)

1995

Bork P, Ouzounis C, Casari G, Schneider R, Sander C, Dolan M, Gilbert W, Gillevet PM. (1995)

Exploring the Mycoplasma capricolum genome: a minimal cell reveals its physiology

Mol. Microbiol. 16(5):955-967. doi: 10.1111/j.1365-2958.1995.tb02321.x
Europe PMC | doi

Sudol M, Bork P, Einbond A, Kastury K, Druck T, Negrini M, Huebner K, Lehman D. (1995)

Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain

J. Biol. Chem. 270(24):14733-14741. doi: 10.1074/jbc.270.24.14733
Europe PMC | doi

Bork P, Margolis B. (1995)

A phosphotyrosine interaction domain

Cell 80(5):693-694. doi: 10.1016/0092-8674(95)90347-x
Europe PMC | doi

Bork P, Ouzounis C, McEntyre J. (1995)

Ready for a motif submission? A proposed checklist

Trends Biochem. Sci. 20(3):104. doi: 10.1016/s0968-0004(00)88974-4
Europe PMC | doi

Bork P, Gellerich J, Groth H, Hooft R, Martin F. (1995)

Divergent evolution of a beta/alpha-barrel subclass: detection of numerous phosphate-binding sites by motif search

Protein Sci. 4(2):268-274. doi: 10.1002/pro.5560040213
Europe PMC | doi


1994

Bork P, Koonin EV. (1994)

A P-loop-like motif in a widespread ATP pyrophosphatase domain: implications for the evolution of sequence motifs and enzyme activity

Proteins 20(4):347-355. doi: 10.1002/prot.340200407
Europe PMC | doi


1993

Meitinger T, Meindl A, Bork P, Rost B, Sander C, Haasemann M, Murken J. (1993)

Molecular modelling of the Norrie disease protein predicts a cystine knot growth factor tertiary structure

Nat. Genet. 5(4):376-380. doi: 10.1038/ng1293-376
Europe PMC | doi

Kolstø AB, Bork P, Kvaløy K, Lindback T, Grønstadt A, Kristensen T, Sander C. (1993)

Prokaryotic members of a new family of putative helicases with similarity to transcription activator SNF2

J. Mol. Biol. 230(2):684-688. doi: 10.1006/jmbi.1993.1185
Europe PMC | doi


1992

Bork P, Ouzounis C, Sander C, Scharf M, Schneider R, Sonnhammer E. (1992)

Comprehensive sequence analysis of the 182 predicted open reading frames of yeast chromosome III

Protein Sci. 1(12):1677-1690. doi: 10.1002/pro.5560011216
Europe PMC | doi

Narahara A, Naterstad K, Kristensen T, Lopez R, Bork P, Kolstø AB. (1992)

Cloning of a gene from Bacillus cereus with homology to the mreB gene from Escherichia coli

Gene 122(1):181-185. doi: 10.1016/0378-1119(92)90047-s
Europe PMC | doi

Bork P, Doolittle RF. (1992)

Proposed acquisition of an animal protein domain by bacteria

Proc. Natl. Acad. Sci. U.S.A. 89(19):8990-8994. doi: 10.1073/pnas.89.19.8990
Europe PMC | doi

Bork P, Sander C, Valencia A. (1992)

An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins

Proc. Natl. Acad. Sci. U.S.A. 89(16):7290-7294. doi: 10.1073/pnas.89.16.7290
Europe PMC | doi

Bork P. (1992)

The modular architecture of vertebrate collagens

FEBS Lett. 307(1):49-54. doi: 10.1016/0014-5793(92)80900-2
Europe PMC | doi

Bork P, Ouzounis C, Sander C, Scharf M, Schneider R, Sonnhammer E. (1992)

What's in a genome?

Nature 358(6384) doi: 10.1038/358287a0
Europe PMC | doi

Bork P, Sander C. (1992)

A large domain common to sperm receptors (Zp2 and Zp3) and TGF-beta type III receptor

FEBS Lett. 300(3):237-240. doi: 10.1016/0014-5793(92)80853-9
Europe PMC | doi

Bork P, Sander C, Valencia A, Bukau B. (1992)

A module of the DnaJ heat shock proteins found in malaria parasites

Trends Biochem. Sci. 17(4) doi: 10.1016/0968-0004(92)90319-5
Europe PMC | doi


1991

Bork P, Rohde K. (1991)

More von Willebrand factor type A domains? Sequence similarities with malaria thrombospondin-related anonymous protein, dihydropyridine-sensitive calcium channel and inter-alpha-trypsin inhibitor

Biochem. J. 279 ( Pt 3):908-910.
Europe PMC

Bork P, Preissner R. (1991)

On alpha-helices terminated by glycine. 2. Recognition by sequence patterns

Biochem. Biophys. Res. Commun. 180(2):666-672. doi: 10.1016/s0006-291x(05)81117-9
Europe PMC | doi

Preissner R, Bork P. (1991)

On alpha-helices terminated by glycine. 1. Identification of common structural features

Biochem. Biophys. Res. Commun. 180(2):660-665. doi: 10.1016/s0006-291x(05)81116-7
Europe PMC | doi

Bork P. (1991)

Shuffled domains in extracellular proteins

FEBS Lett. 286(1-2):47-54. doi: 10.1016/0014-5793(91)80937-x
Europe PMC | doi

Bork P. (1991)

Complement components C1r/C1s, bone morphogenic protein 1 and Xenopus laevis developmentally regulated protein UVS.2 share common repeats

FEBS Lett. 282(1):9-12. doi: 10.1016/0014-5793(91)80433-4
Europe PMC | doi


1990

Bork P, Rohde K. (1990)

Sequence similarities between tryptophan synthase beta subunit and other pyridoxal-phosphate-dependent enzymes

Biochem. Biophys. Res. Commun. 171(3):1319-1325. doi: 10.1016/0006-291x(90)90830-g
Europe PMC | doi

Bork P, Grunwald C. (1990)

Recognition of different nucleotide-binding sites in primary structures using a property-pattern approach

Eur. J. Biochem. 191(2):347-358. doi: 10.1111/j.1432-1033.1990.tb19129.x
Europe PMC | doi


1989

Bork P. (1989)

Recognition of functional regions in primary structures using a set of property patterns

FEBS Lett. 257(1):191-195. doi: 10.1016/0014-5793(89)81818-6
Europe PMC | doi