EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
Biography
PhD 1991, University of Freiburg, Germany
Postdoctoral research at Harvard University, Cambridge, USA.
Group leader at EMBL Grenoble since 1995.
Head of Unit at EMBL Heidelberg since 2007.
Joint appointment with the Genome Biology Unit.
ERC Advanced Investigator.
Publications
Total: 113 publication(s)
2021
Girbig M, Misiaszek AD, Vorländer MK, Lafita A, Grötsch H, Baudin F, Bateman A, Müller CW. (2021)
Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states.
Nat Struct Mol Biol 28(2):210-219. doi: 10.1038/s41594-020-00555-5
Europe PMC | doi
2020
Vorländer MK, Jungblut A, Karius K, Baudin F, Grötsch H, Kosinski J, Müller CW. (2020)
Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation.
Nat Commun 11(1) doi: 10.1038/s41467-020-18707-y
Europe PMC | doi
Allegretti M, Zimmerli CE, Rantos V, Wilfling F, Ronchi P, Fung HKH, Lee CW, Hagen W, Turoňová B, Karius K, Börmel M, Zhang X, Müller CW, Schwab Y, Mahamid J, Pfander B, Kosinski J, Beck M. (2020)
In-cell architecture of the nuclear pore and snapshots of its turnover.
Nature 586(7831):796-800. doi: 10.1038/s41586-020-2670-5
Europe PMC | doi
Vorländer MK, Baudin F, Moir RD, Wetzel R, Hagen WJH, Willis IM, Müller CW. (2020)
Structural basis for RNA polymerase III transcription repression by Maf1.
Nat. Struct. Mol. Biol. 27(3):229-232. doi: 10.1038/s41594-020-0383-y
Europe PMC | doi
2019
Sadian Y, Baudin F, Tafur L, Murciano B, Wetzel R, Weis F, Müller CW. (2019)
Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun 10(1) doi: 10.1038/s41467-019-13510-w
Europe PMC | doi
Dauden MI, Jaciuk M, Weis F, Lin TY, Kleindienst C, Abbassi NEH, Khatter H, Krutyhołowa R, Breunig KD, Kosinski J, Müller CW, Glatt S. (2019)
Molecular basis of tRNA recognition by the Elongator complex.
Sci Adv 5(7) doi: 10.1126/sciadv.aaw2326
Europe PMC | doi
De I, Müller CW. (2019)
Unleashing the power of ASH1L methyltransferase.
Structure 27(5):727-728. doi: 10.1016/j.str.2019.04.012
Europe PMC | doi
Tafur L, Sadian Y, Hanske J, Wetzel R, Weis F, Müller CW. (2019)
The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.
Elife 8 doi: 10.7554/eLife.43204
Europe PMC | doi
2018
De I, Chittock EC, Grötsch H, Miller TCR, McCarthy AA, Müller CW. (2018)
Structural basis for the activation of the deubiquitinase Calypso by the Polycomb protein ASX.
Structure 27(3):528-536.e4. doi: 10.1016/j.str.2018.11.013
Europe PMC | doi
Weis F, Menting JG, Margetts MB, Chan SJ, Xu Y, Tennagels N, Wohlfart P, Langer T, Müller CW, Dreyer MK, Lawrence MC. (2018)
The signalling conformation of the insulin receptor ectodomain.
Nat Commun 9(1) doi: 10.1038/s41467-018-06826-6
Europe PMC | doi
Hanske J, Sadian Y, Müller CW. (2018)
The cryo-EM resolution revolution and transcription complexes.
Curr. Opin. Struct. Biol. 52:8-15. doi: 10.1016/j.sbi.2018.07.002
Europe PMC | doi
Becher I, Andrés-Pons A, Romanov N, Stein F, Schramm M, Baudin F, Helm D, Kurzawa N, Mateus A, Mackmull MT, Typas A, Müller CW, Bork P, Beck M, Savitski MM. (2018)
Pervasive protein thermal stability variation during the cell cycle.
Cell 173(6) doi: 10.1016/j.cell.2018.03.053
Europe PMC | doi
Dauden MI, Jaciuk M, Müller CW, Glatt S. (2018)
Structural asymmetry in the eukaryotic Elongator complex.
FEBS Lett 592(4) doi: 10.1002/1873-3468.12865
Europe PMC | doi
Vorländer MK, Khatter H, Wetzel R, Hagen WJH, Müller CW. (2018)
Molecular mechanism of promoter opening by RNA polymerase III.
Nature 553(7688):295-300. doi: 10.1038/nature25440
Europe PMC | doi
2017
Cusack S, Müller CW. (2017)
Editorial overview: Protein-nucleic acid interactions: An expanding universe.
Curr. Opin. Struct. Biol. 47 doi: 10.1016/j.sbi.2017.11.004
Europe PMC | doi
Khatter H, Vorländer MK, Müller CW. (2017)
RNA polymerase I and III: similar yet unique.
Curr Opin Struct Biol 47:88-94. doi: 10.1016/j.sbi.2017.05.008
Europe PMC | doi
Sadian Y, Tafur L, Kosinski J, Jakobi AJ, Wetzel R, Buczak K, Hagen WJ, Beck M, Sachse C, Müller CW. (2017)
Structural insights into transcription initiation by yeast RNA polymerase I.
EMBO J 36(18) doi: 10.15252/embj.201796958
Europe PMC | doi
Ichikawa Y, Connelly CF, Appleboim A, Miller TC, Jacobi H, Abshiru NA, Chou HJ, Chen Y, Sharma U, Zheng Y, Thomas PM, Chen HV, Bajaj V, Müller CW, Kelleher NL, Friedman N, Bolon DN, Rando OJ, Kaufman PD. (2017)
A synthetic biology approach to probing nucleosome symmetry.
Elife 6 doi: 10.7554/eLife.28836
Europe PMC | doi
Patel J, Lama L, Hoffmann NA, Cobo J, Müller CW, Ryan K. (2017)
RNA polymerase III initiation on coligo DNA templates containing loops of variable sequence, size and nucleotide chemistry.
Gene 612:49-54. doi: 10.1016/j.gene.2016.09.001
Europe PMC | doi
Jeske M, Müller CW, Ephrussi A. (2017)
The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage.
Genes Dev 31(9) doi: 10.1101/gad.297051.117
Europe PMC | doi
Chittock EC, Latwiel S, Miller TC, Müller CW. (2017)
Molecular architecture of polycomb repressive complexes.
Biochem. Soc. Trans. 45(1):193-205. doi: 10.1042/bst20160173
Europe PMC | doi
2016
Miller TC, Simon B, Rybin V, Grötsch H, Curtet S, Khochbin S, Carlomagno T, Müller CW. (2016)
A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT
Nat Commun 7:13855. doi: 10.1038/ncomms13855
Europe PMC | doi
Tafur L, Sadian Y, Hoffmann NA, Jakobi AJ, Wetzel R, Hagen WJ, Sachse C, Müller CW. (2016)
Molecular Structures of Transcribing RNA Polymerase I
Mol Cell. 64(6):1135-1143. doi: 10.1016/j.molcel.2016.11.013
Europe PMC | doi
Dauden MI, Kosinski J, Kolaj-Robin O, Desfosses A, Ori A, Faux C, Hoffmann NA, Onuma OF, Breunig KD, Beck M, Sachse C, Séraphin B, Glatt S, Müller CW. (2016)
Architecture of the yeast Elongator complex
EMBO Rep. 18(2):e201643353. doi: 10.15252/embr.201643353
Europe PMC | doi
Glatt S, Zabel R, Kolaj-Robin O, Onuma OF, Baudin F, Graziadei A, Taverniti V, Lin TY, Baymann F, Séraphin B, Breunig KD, Müller CW. (2016)
Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi.
Nat. Struct. Mol. Biol. 23(9):794-802. doi: 10.1038/nsmb.3265
Europe PMC | doi
Hoffmann NA, Sadian Y, Tafur L, Kosinski J, Müller CW. (2016)
Specialization versus Conservation: How Pol I and Pol III use the conserved architecture of the pre-initiation complex for specialized transcription.
Transcription 7(4):127-132. doi: 10.1080/21541264.2016.1203628
Europe PMC | doi
Hoffmann NA, Jakobi AJ, Vorländer MK, Sachse C, Müller CW. (2016)
Transcribing RNA polymerase III observed by electron cryo-microscopy.
FEBS J. 283(15):2811-2819. doi: 10.1111/febs.13732
Europe PMC | doi
Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M, Simon B, Bouvier G, Batista PR, Müller CW, Beck M, Nilges M. (2016)
Automated structure modeling of large protein assemblies using crosslinks as distance restraints.
Nat. Methods 13(6) doi: 10.1038/nmeth.3838
Europe PMC | doi
Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas S, Baudin F, Samee MA, He D, Small EM, Mileikovsky M, Nagy A, Holloway AK, Pollard KS, Müller CW, Bruneau BG. (2016)
Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis.
Cell 164(5) doi: 10.1016/j.cell.2016.01.004
Europe PMC | doi
Silva-Martin N, Daudén MI, Glatt S, Hoffmann NA, Kastritis P, Bork P, Beck M, Müller CW. (2016)
The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex.
PLoS ONE 11(1) doi: 10.1371/journal.pone.0146457
Europe PMC | doi
2015
Hoffmann NA, Jakobi AJ, Moreno-Morcillo M, Glatt S, Kosinski J, Hagen WJ, Sachse C, Müller CW. (2015)
Molecular structures of unbound and transcribing RNA polymerase III.
Nature 528(7581):231-236. doi: 10.1038/nature16143
Europe PMC | doi
Jeske M, Bordi M, Glatt S, Müller S, Rybin V, Müller CW, Ephrussi A. (2015)
The crystal structure of the Drosophila germline inducer oskar identifies two domains with distinct Vasa helicase- and RNA-binding activities.
Cell Rep 12(4):1-12. doi: 10.1016/j.celrep.2015.06.055
Europe PMC | doi
Male G, von Appen A, Glatt S, Taylor NM, Cristovao M, Groetsch H, Beck M, Müller CW. (2015)
Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.
Nat Commun 6 doi: 10.1038/ncomms8387
Europe PMC | doi
Kosinski J, von Appen A, Ori A, Karius K, Müller CW, Beck M. (2015)
Xlink Analyzer: Software for analysis and visualization of cross-linking data in the context of three-dimensional structures.
J. Struct. Biol. 189(3):177-183. doi: 10.1016/j.jsb.2015.01.014
Europe PMC | doi
Glatt S, Zabel R, Vonkova I, Kumar A, Netz DJ, Pierik AJ, Rybin V, Lill R, Gavin A, Balbach J, Breunig KD, Müller CW. (2015)
Structure of the Kti11/Kti13 Heterodimer and Its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.
Structure 23(1):149-160. doi: 10.1016/j.str.2014.11.008
Europe PMC | doi
2014
Bock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-Cepas J, Powell ST, Kastritis PL, Smyshlyaev G, Vonkova I, Kirkpatrick J, Doerks T, Nesme L, Baßler J, Kos M, Hurt E, Carlomagno T, Gavin AC, Barabas O, Müller CW, van Noort V, Beck M, Bork P. (2014)
An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.
Nucleic Acids Res. 42(22):13525-13533. doi: 10.1093/nar/gku1147
Europe PMC | doi
Müller J, Müller CW. (2014)
Structural biology: Enzyme-chromatin complex visualized.
Nature 514(7524):572-573. doi: 10.1038/514572a
Europe PMC | doi
Moreno-Morcillo M, Taylor NM, Gruene T, Legrand P, Rashid UJ, Ruiz FM, Steuerwald U, Müller CW, Fernández-Tornero C. (2014)
Solving the RNA polymerase I structural puzzle.
Acta Crystallogr. D Biol. Crystallogr. 70(Pt 10):2570-2582. doi: 10.1107/s1399004714015788
Europe PMC | doi
Kalb R, Latwiel S, Baymaz HI, Jansen PW, Müller CW, Vermeulen M, Müller J. (2014)
Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression
Nat. Struct. Mol. Biol. 21(6):569-571. doi: 10.1038/nsmb.2833
Europe PMC | doi
2013
Alfieri C, Gambetta MC, Matos R, Glatt S, Sehr P, Fraterman S, Wilm M, Müller J, Müller CW. (2013)
Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements.
Genes Dev. 27(21):2367-2379. doi: 10.1101/gad.226621.113
Europe PMC | doi
Fernández-Tornero C, Moreno-Morcillo M, Rashid UJ, Taylor NM, Ruiz FM, Gruene T, Legrand P, Steuerwald U, Müller CW. (2013)
Crystal structure of the 14-subunit RNA polymerase I
Nature 502(7473):644-649. doi: 10.1038/nature12636
Europe PMC | doi
Taylor NM, Baudin F, von Scheven G, Müller CW. (2013)
RNA polymerase III-specific general transcription factor IIIC contains a heterodimer resembling TFIIF Rap30/Rap74
Nucleic Acids Res. 41(19):9183-9196. doi: 10.1093/nar/gkt664
Europe PMC | doi
Dian C, Bernaudat F, Langer K, Oliva MF, Fornerod M, Schoehn G, Müller CW, Petosa C. (2013)
Structure of a truncation mutant of the nuclear export factor CRM1 provides insights into the auto-inhibitory role of its C-terminal helix
Structure 21(8):1338-1349. doi: 10.1016/j.str.2013.06.003
Europe PMC | doi
Taylor NM, Glatt S, Hennrich ML, von Scheven G, Grötsch H, Fernández-Tornero C, Rybin V, Gavin AC, Kolb P, Müller CW. (2013)
Structural and functional characterization of a phosphatase domain within yeast general transcription factor IIIC
J. Biol. Chem. 288(21):15110-15120. doi: 10.1074/jbc.m112.427856
Europe PMC | doi
Glatt S, Müller CW. (2013)
Structural insights into Elongator function
Curr. Opin. Struct. Biol. 23(2):235-242. doi: 10.1016/j.sbi.2013.02.009
Europe PMC | doi
Baudin F, Müller CW. (2013)
Bacterial expression, purification, and crystallization of tyrosine phosphorylated STAT proteins
Methods Mol. Biol. 967:301-317. doi: 10.1007/978-1-62703-242-1_21
Europe PMC | doi
2012
Glatt S, Létoquart J, Faux C, Taylor NM, Séraphin B, Müller CW. (2012)
The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase
Nat. Struct. Mol. Biol. 19(3):314-320. doi: 10.1038/nsmb.2234
Europe PMC | doi
Glatt S, Séraphin B, Müller CW. (2012)
Elongator: transcriptional or translational regulator?
Transcription 3(6):273-276. doi: 10.4161/trns.21525
Europe PMC | doi
2011
Nowak AJ, Alfieri C, Stirnimann CU, Rybin V, Baudin F, Ly-Hartig N, Lindner D, Müller CW. (2011)
Chromatin-modifying complex component Nurf55/p55 associates with histones H3 and H4 and polycomb repressive complex 2 subunit Su(z)12 through partially overlapping binding sites
J. Biol. Chem. 286(26):23388-23396. doi: 10.1074/jbc.m110.207407
Europe PMC | doi
Glatt S, Alfieri C, Müller CW. (2011)
Recognizing and remodeling the nucleosome
Curr. Opin. Struct. Biol. 21(3):335-341. doi: 10.1016/j.sbi.2011.02.003
Europe PMC | doi
Boulo S, Akarsu H, Lotteau V, Müller CW, Ruigrok RW, Baudin F. (2011)
Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein
Virology 409(1):84-90. doi: 10.1016/j.virol.2010.10.001
Europe PMC | doi
Fernández-Tornero C, Böttcher B, Rashid UJ, Müller CW. (2011)
Analyzing RNA polymerase III by electron cryomicroscopy
RNA Biol 8(5):760-765. doi: 10.4161/rna.8.5.16021
Europe PMC | doi
Lane LA, Fernández-Tornero C, Zhou M, Morgner N, Ptchelkine D, Steuerwald U, Politis A, Lindner D, Gvozdenovic J, Gavin AC, Müller CW, Robinson CV. (2011)
Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III
Structure 19(1):90-100. doi: 10.1016/j.str.2010.11.009
Europe PMC | doi
Langer K, Dian C, Rybin V, Müller CW, Petosa C. (2011)
Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain
PLoS ONE 6(2):e17011. doi: 10.1371/journal.pone.0017011
Europe PMC | doi
2010
Fernández-Tornero C, Böttcher B, Rashid UJ, Steuerwald U, Flörchinger B, Devos DP, Lindner D, Müller CW. (2010)
Conformational flexibility of RNA polymerase III during transcriptional elongation
EMBO J. 29(22):3762-3772. doi: 10.1038/emboj.2010.266
Europe PMC | doi
Gajda A, Towpik J, Steuerwald U, Müller CW, Lefebvre O, Boguta M. (2010)
Full repression of RNA polymerase III transcription requires interaction between two domains of its negative regulator Maf1
J. Biol. Chem. 285(46):35719-35727. doi: 10.1074/jbc.m110.125286
Europe PMC | doi
Gallego O, Betts MJ, Gvozdenovic-Jeremic J, Maeda K, Matetzki C, Aguilar-Gurrieri C, Beltran-Alvarez P, Bonn S, Fernández-Tornero C, Jensen LJ, Kuhn M, Trott J, Rybin V, Müller CW, Bork P, Kaksonen M, Russell RB, Gavin AC. (2010)
A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae
Mol. Syst. Biol. 6:430. doi: 10.1038/msb.2010.87
Europe PMC | doi
Mattaj IW, Müller CW. (2010)
Solving the NES problem
Nat. Struct. Mol. Biol. 17(11):1288-1289. doi: 10.1038/nsmb1110-1288
Europe PMC | doi
Stirnimann CU, Petsalaki E, Russell RB, Müller CW. (2010)
WD40 proteins propel cellular networks
Trends Biochem. Sci. 35(10):565-574. doi: 10.1016/j.tibs.2010.04.003
Europe PMC | doi
Stirnimann CU, Ptchelkine D, Grimm C, Müller CW. (2010)
Structural basis of TBX5-DNA recognition: the T-box domain in its DNA-bound and -unbound form
J. Mol. Biol. 400(1):71-81. doi: 10.1016/j.jmb.2010.04.052
Europe PMC | doi
Rousseaux S, Petosa C, Müller CW, Khochbin S. (2010)
[A novel key element in post-meiotic male genome reprogramming]
Med Sci (Paris) 26(2):130-132. doi: 10.1051/medsci/2010262130
Europe PMC | doi
2009
Morinière J, Rousseaux S, Steuerwald U, Soler-López M, Curtet S, Vitte AL, Govin J, Gaucher J, Sadoul K, Hart DJ, Krijgsveld J, Khochbin S, Müller CW, Petosa C. (2009)
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
Nature 461(7264):664-668. doi: 10.1038/nature08397
Europe PMC | doi
Grimm C, Matos R, Ly-Hartig N, Steuerwald U, Lindner D, Rybin V, Müller J, Müller CW. (2009)
Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt
EMBO J. 28(13):1965-1977. doi: 10.1038/emboj.2009.147
Europe PMC | doi
2008
Hamès C, Ptchelkine D, Grimm C, Thevenon E, Moyroud E, Gérard F, Martiel JL, Benlloch R, Parcy F, Müller CW. (2008)
Structural basis for LEAFY floral switch function and similarity with helix-turn-helix proteins
EMBO J. 27(19):2628-2637. doi: 10.1038/emboj.2008.184
Europe PMC | doi
Clapier CR, Chakravarthy S, Petosa C, Fernández-Tornero C, Luger K, Müller CW. (2008)
Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer
Proteins 71(1):1-7. doi: 10.1002/prot.21720
Europe PMC | doi
2007
Grimm C, de Ayala Alonso AG, Rybin V, Steuerwald U, Ly-Hartig N, Fischle W, Müller J, Müller CW. (2007)
Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg
EMBO Rep. 8(11):1031-1037. doi: 10.1038/sj.embor.7401085
Europe PMC | doi
Fernández-Tornero C, Böttcher B, Riva M, Carles C, Steuerwald U, Ruigrok RW, Sentenac A, Müller CW, Schoehn G. (2007)
Insights into transcription initiation and termination from the electron microscopy structure of yeast RNA polymerase III
Mol. Cell 25(6):813-823. doi: 10.1016/j.molcel.2007.02.016
Europe PMC | doi
Berger JM, Muller CW. (2007)
Protein-nucleic acid interactions: some assembly required - Editorial overview
CURR OPIN STRUC BIOL 17(1):77-79. doi: 10.1016/j.sbi.2007.01.010
doi
2006
Mylona A, Fernández-Tornero C, Legrand P, Haupt M, Sentenac A, Acker J, Müller CW. (2006)
Structure of the tau60/Delta tau91 subcomplex of yeast transcription factor IIIC: insights into preinitiation complex assembly
Mol. Cell 24(2):221-232. doi: 10.1016/j.molcel.2006.08.013
Europe PMC | doi
Boyault C, Gilquin B, Zhang Y, Rybin V, Garman E, Meyer-Klaucke W, Matthias P, Müller CW, Khochbin S. (2006)
HDAC6-p97/VCP controlled polyubiquitin chain turnover
EMBO J. 25(14):3357-3366. doi: 10.1038/sj.emboj.7601210
Europe PMC | doi
Conti E, Müller CW, Stewart M. (2006)
Karyopherin flexibility in nucleocytoplasmic transport
Curr. Opin. Struct. Biol. 16(2):237-244. doi: 10.1016/j.sbi.2006.03.010
Europe PMC | doi
Morand P, Budayova-Spano M, Perrissin M, Müller CW, Petosa C. (2006)
Expression, purification, crystallization and preliminary X-ray analysis of a C-terminal fragment of the Epstein-Barr virus ZEBRA protein
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62(Pt 3):210-214. doi: 10.1107/s1744309106002971
Europe PMC | doi
Mylona A, Acker J, Fernández-Tornero C, Sentenac A, Müller CW. (2006)
Expression, proteolytic analysis, reconstitution, and crystallization of the tau60/tau91 subcomplex of yeast TFIIIC
Protein Expr. Purif. 45(2):255-261. doi: 10.1016/j.pep.2005.06.013
Europe PMC | doi
Petosa C, Morand P, Baudin F, Moulin M, Artero JB, Müller CW. (2006)
Structural basis of lytic cycle activation by the Epstein-Barr virus ZEBRA protein
Mol. Cell 21(4):565-572. doi: 10.1016/j.molcel.2006.01.006
Europe PMC | doi
Morand, P & Müller, C.W. (2006)
Protein/DNA Interaction
In: Ganten, D. & Ruckpaul, K.(Eds.), Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine. Springer. pp 1538-1542.
2005
Hartlepp KF, Fernández-Tornero C, Eberharter A, Grüne T, Müller CW, Becker PB. (2005)
The histone fold subunits of Drosophila CHRAC facilitate nucleosome sliding through dynamic DNA interactions
Mol. Cell. Biol. 25(22):9886-9896. doi: 10.1128/mcb.25.22.9886-9896.2005
Europe PMC | doi
Garcia-Robles I, Akarsu H, Müller CW, Ruigrok RW, Baudin F. (2005)
Interaction of influenza virus proteins with nucleosomes
Virology 332(1):329-336. doi: 10.1016/j.virol.2004.09.036
Europe PMC | doi
2004
Petosa C, Schoehn G, Askjaer P, Bauer U, Moulin M, Steuerwald U, Soler-López M, Baudin F, Mattaj IW, Müller CW. (2004)
Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex
Mol. Cell 16(5):761-775. doi: 10.1016/j.molcel.2004.11.018
Europe PMC | doi
Angelov D, Lenouvel F, Hans F, Müller CW, Bouvet P, Bednar J, Moudrianakis EN, Cadet J, Dimitrov S. (2004)
The histone octamer is invisible when NF-kappaB binds to the nucleosome
J. Biol. Chem. 279(41):42374-42382. doi: 10.1074/jbc.m407235200
Europe PMC | doi
Soler-Lopez M, Petosa C, Fukuzawa M, Ravelli R, Williams JG, Müller CW. (2004)
Structure of an activated Dictyostelium STAT in its DNA-unbound form
Mol. Cell 13(6):791-804. doi: 10.1016/s1097-2765(04)00130-3
Europe PMC | doi
2003
Akarsu H, Burmeister WP, Petosa C, Petit I, Müller CW, Ruigrok RW, Baudin F. (2003)
Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2)
EMBO J. 22(18):4646-4655. doi: 10.1093/emboj/cdg449
Europe PMC | doi
Grüne T, Brzeski J, Eberharter A, Clapier CR, Corona DF, Becker PB, Müller CW. (2003)
Crystal structure and functional analysis of a nucleosome recognition module of the remodeling factor ISWI
Mol. Cell 12(2):449-460. doi: 10.1016/s1097-2765(03)00273-9
Europe PMC | doi
Angelov D, Charra M, Müller CW, Cadet J, Dimitrov S. (2003)
Solution study of the NF-kappaB p50-DNA complex by UV laser protein-DNA cross-linking
Photochem. Photobiol. 77(6):592-596. doi: 10.1562/0031-8655(2003)077<0592:ssotnp>2.0.co;2
Europe PMC | doi
Cohen SX, Moulin M, Hashemolhosseini S, Kilian K, Wegner M, Müller CW. (2003)
Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition
EMBO J. 22(8):1835-1845. doi: 10.1093/emboj/cdg182
Europe PMC | doi
Müller CW, Soler-Lopez M, Gewinner C, Groner B. (2003)
X-ray crystal structure of STAT proteins and structure-activity relationships
Springer Netherlands.doi: 10.1007/978-94-017-3000-6_21
Europe PMC | doi
2002
Cohen SX, Moulin M, Schilling O, Meyer-Klaucke W, Schreiber J, Wegner M, Müller CW. (2002)
The GCM domain is a Zn-coordinating DNA-binding domain
FEBS Lett. 528(1-3):95-100. doi: 10.1016/s0014-5793(02)03257-x
Europe PMC | doi
Coll M, Seidman JG, Müller CW. (2002)
Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome
Structure 10(3):343-356. doi: 10.1016/s0969-2126(02)00722-0
Europe PMC | doi
2001
Michel F, Soler-Lopez M, Petosa C, Cramer P, Siebenlist U, Müller CW. (2001)
Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family
EMBO J. 20(22):6180-6190. doi: 10.1093/emboj/20.22.6180
Europe PMC | doi
Andrade MA, Petosa C, O'Donoghue SI, Müller CW, Bork P. (2001)
Comparison of ARM and HEAT protein repeats
J. Mol. Biol. 309(1):1-18. doi: 10.1006/jmbi.2001.4624
Europe PMC | doi
Müller CW. (2001)
Transcription factors: global and detailed views
Curr. Opin. Struct. Biol. 11(1):26-32. doi: 10.1016/s0959-440x(00)00163-9
Europe PMC | doi
Müller CW. (2001)
DNA recognition by NF kappa B and STAT transcription factors
Ernst Schering Res. Found. Workshop 34(34):143-166.
Europe PMC
2000
Cingolani G, Lashuel HA, Gerace L, Müller CW. (2000)
Nuclear import factors importin alpha and importin beta undergo mutually induced conformational changes upon association
FEBS Lett. 484(3):291-298. doi: 10.1016/s0014-5793(00)02154-2
Europe PMC | doi
1999
Cramer P, Varrot A, Barillas-Mury C, Kafatos FC, Müller CW. (1999)
Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA
Structure 7(7):841-852. doi: 10.1016/s0969-2126(99)80107-5
Europe PMC | doi
Cingolani G, Petosa C, Weis K, Müller CW. (1999)
Structure of importin-beta bound to the IBB domain of importin-alpha
Nature 399(6733):221-229. doi: 10.1038/20367
Europe PMC | doi
Basson CT, Huang T, Lin RC, Bachinsky DR, Weremowicz S, Vaglio A, Bruzzone R, Quadrelli R, Lerone M, Romeo G, Silengo M, Pereira A, Krieger J, Mesquita SF, Kamisago M, Morton CC, Pierpont ME, Müller CW, Seidman JG, Seidman CE. (1999)
Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations
Proc. Natl. Acad. Sci. U.S.A. 96(6):2919-2924. doi: 10.1073/pnas.96.6.2919
Europe PMC | doi
Cramer P, Müller CW. (1999)
A firm hand on NFkappaB: structures of the IkappaBalpha-NFkappaB complex
Structure 7(1):R1-6. doi: 10.1016/s0969-2126(99)80002-1
Europe PMC | doi
1998
Becker S, Corthals GL, Aebersold R, Groner B, Müller CW. (1998)
Expression of a tyrosine phosphorylated, DNA binding Stat3beta dimer in bacteria
FEBS Lett. 441(1):141-147. doi: 10.1016/s0014-5793(98)01543-9
Europe PMC | doi
Becker S, Groner B, Müller CW. (1998)
Three-dimensional structure of the Stat3beta homodimer bound to DNA
Nature 394(6689):145-151. doi: 10.1038/28101
Europe PMC | doi
1997
Cramer P, Larson CJ, Verdine GL, Müller CW. (1997)
Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution
EMBO J. 16(23):7078-7090. doi: 10.1093/emboj/16.23.7078
Europe PMC | doi
Müller CW, Herrmann BG. (1997)
Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor
Nature 389(6653):884-888. doi: 10.1038/39929
Europe PMC | doi