EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany

Biography

  • PhD 1989 University of Victoria, BC, Canada

  • and IBMC, Strasbourg, France.

  • Postdoctoral work IBMC, Strasbourg, France (1989-1991)

  • and EMBL Grenoble from 1991 until 1993.

  • Staff scientist at EMBL Grenoble from 1993 until 2002.

  • Researcher at the CNRS since 2002.

Publications

Total: 44 publication(s)

2016

Glatt S, Zabel R, Kolaj-Robin O, Onuma OF, Baudin F, Graziadei A, Taverniti V, Lin TY, Baymann F, Séraphin B, Breunig KD, Müller CW. (2016)

Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi.

Nat. Struct. Mol. Biol. 23(9):794-802. doi: 10.1038/nsmb.3265
Europe PMC | doi

Thierry E, Guilligay D, Kosinski J, Bock T, Gaudon S, Round A, Pflug A, Hengrung N, El Omari K, Baudin F, Hart DJ, Beck M, Cusack S. (2016)

Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.

Mol. Cell 61(1):125-137. doi: 10.1016/j.molcel.2015.11.016
Europe PMC | doi

Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas S, Baudin F, Samee MA, He D, Small EM, Mileikovsky M, Nagy A, Holloway AK, Pollard KS, Müller CW, Bruneau BG. (2016)

Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis.

Cell doi: 10.1016/j.cell.2016.01.004
Europe PMC | doi


2013

Taylor NM, Baudin F, von Scheven G, Müller CW. (2013)

RNA polymerase III-specific general transcription factor IIIC contains a heterodimer resembling TFIIF Rap30/Rap74

Nucleic Acids Res. 41(19):9183-9196. doi: 10.1093/nar/gkt664
Europe PMC | doi

Chenavas S, Estrozi LF, Slama-Schwok A, Delmas B, Di Primo C, Baudin F, Li X, Crépin T, Ruigrok RW. (2013)

Monomeric nucleoprotein of influenza A virus

PLoS Pathog. 9(3):e1003275. doi: 10.1371/journal.ppat.1003275
Europe PMC | doi

Baudin F, Müller CW. (2013)

Bacterial expression, purification, and crystallization of tyrosine phosphorylated STAT proteins

Methods Mol. Biol. 967:301-317. doi: 10.1007/978-1-62703-242-1_21
Europe PMC | doi

Pérard J, Leyrat C, Baudin F, Drouet E, Jamin M. (2013)

Structure of the full-length HCV IRES in solution

Nat Commun 4:1612. doi: 10.1038/ncomms2611
Europe PMC | doi


2012

Moisy D, Avilov SV, Jacob Y, Laoide BM, Ge X, Baudin F, Naffakh N, Jestin JL. (2012)

HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication

J. Virol. 86(17):9122-9133. doi: 10.1128/jvi.00789-12
Europe PMC | doi


2011

Nowak AJ, Alfieri C, Stirnimann CU, Rybin V, Baudin F, Ly-Hartig N, Lindner D, Müller CW. (2011)

Chromatin-modifying complex component Nurf55/p55 associates with histones H3 and H4 and polycomb repressive complex 2 subunit Su(z)12 through partially overlapping binding sites

J. Biol. Chem. 286(26):23388-23396. doi: 10.1074/jbc.m110.207407
Europe PMC | doi

Akarsu H, Iwatsuki-Horimoto K, Noda T, Kawakami E, Katsura H, Baudin F, Horimoto T, Kawaoka Y. (2011)

Structure-based design of NS2 mutants for attenuated influenza A virus vaccines

Virus Res. 155(1):240-248. doi: 10.1016/j.virusres.2010.10.014
Europe PMC | doi

Boulo S, Akarsu H, Lotteau V, Müller CW, Ruigrok RW, Baudin F. (2011)

Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein

Virology 409(1):84-90. doi: 10.1016/j.virol.2010.10.001
Europe PMC | doi


2009

Dias A, Bouvier D, Crépin T, McCarthy AA, Hart DJ, Baudin F, Cusack S, Ruigrok RW. (2009)

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

Nature 458(7240):914-918. doi: 10.1038/nature07745
Europe PMC | doi

Pérard J, Rasia R, Medenbach J, Ayala I, Boisbouvier J, Drouet E, Baudin F. (2009)

Human initiation factor eIF3 subunit b interacts with HCV IRES RNA through its N-terminal RNA recognition motif

FEBS Lett. 583(1):70-74. doi: 10.1016/j.febslet.2008.11.025
Europe PMC | doi


2007

Boulo S, Akarsu H, Ruigrok RW, Baudin F. (2007)

Nuclear traffic of influenza virus proteins and ribonucleoprotein complexes

Virus Res. 124(1-2):12-21. doi: 10.1016/j.virusres.2006.09.013
Europe PMC | doi

Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP, Hart DJ. (2007)

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit

Nat. Struct. Mol. Biol. 14(3):229-233. doi: 10.1038/nsmb1212
Europe PMC | doi


2006

Petosa C, Morand P, Baudin F, Moulin M, Artero JB, Müller CW. (2006)

Structural basis of lytic cycle activation by the Epstein-Barr virus ZEBRA protein

Mol. Cell 21(4):565-572. doi: 10.1016/j.molcel.2006.01.006
Europe PMC | doi


2005

Garcia-Robles I, Akarsu H, Müller CW, Ruigrok RW, Baudin F. (2005)

Interaction of influenza virus proteins with nucleosomes

Virology 332(1):329-336. doi: 10.1016/j.virol.2004.09.036
Europe PMC | doi


2004

Petosa C, Schoehn G, Askjaer P, Bauer U, Moulin M, Steuerwald U, Soler-López M, Baudin F, Mattaj IW, Müller CW. (2004)

Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex

Mol. Cell 16(5):761-775. doi: 10.1016/j.molcel.2004.11.018
Europe PMC | doi

Arzt S, Petit I, Burmeister WP, Ruigrok RW, Baudin F. (2004)

Structure of a knockout mutant of influenza virus M1 protein that has altered activities in membrane binding, oligomerisation and binding to NEP (NS2)

Virus Res. 99(2):115-119. doi: 10.1016/j.virusres.2003.10.010
Europe PMC | doi


2003

Akarsu H, Burmeister WP, Petosa C, Petit I, Müller CW, Ruigrok RW, Baudin F. (2003)

Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2)

EMBO J. 22(18):4646-4655. doi: 10.1093/emboj/cdg449
Europe PMC | doi


2002

Iseni F, Baudin F, Garcin D, Marq JB, Ruigrok RW, Kolakofsky D. (2002)

Chemical modification of nucleotide bases and mRNA editing depend on hexamer or nucleoprotein phase in Sendai virus nucleocapsids

RNA 8(8):1056-1067. doi: 10.1017/s1355838202029977
Europe PMC | doi


2001

Buisson M, Valette E, Hernandez JF, Baudin F, Ebel C, Morand P, Seigneurin JM, Arlaud GJ, Ruigrok RW. (2001)

Functional determinants of the Epstein-Barr virus protease

J. Mol. Biol. 311(1):217-228. doi: 10.1006/jmbi.2001.4854
Europe PMC | doi

Baudin F, Petit I, Weissenhorn W, Ruigrok RW. (2001)

In vitro dissection of the membrane and RNP binding activities of influenza virus M1 protein

Virology 281(1):102-108. doi: 10.1006/viro.2000.0804
Europe PMC | doi

Arzt S, Baudin F, Barge A, Timmins P, Burmeister WP, Ruigrok RW. (2001)

Combined results from solution studies on intact influenza virus M1 protein and from a new crystal form of its N-terminal domain show that M1 is an elongated monomer

Virology 279(2):439-446. doi: 10.1006/viro.2000.0727
Europe PMC | doi


2000

Iseni F, Baudin F, Blondel D, Ruigrok RW. (2000)

Structure of the RNA inside the vesicular stomatitis virus nucleocapsid

RNA 6(2):270-281. doi: 10.1017/s135583820099109x
Europe PMC | doi


1998

Iseni F, Barge A, Baudin F, Blondel D, Ruigrok RW. (1998)

Characterization of rabies virus nucleocapsids and recombinant nucleocapsid-like structures

J. Gen. Virol. 79 ( Pt 12):2909-2919.
Europe PMC


1997

Elster C, Larsen K, Gagnon J, Ruigrok RW, Baudin F. (1997)

Influenza virus M1 protein binds to RNA through its nuclear localization signal

J. Gen. Virol. 78 ( Pt 7):1589-1596.
Europe PMC

Klumpp K, Ruigrok RW, Baudin F. (1997)

Roles of the influenza virus polymerase and nucleoprotein in forming a functional RNP structure

EMBO J. 16(6):1248-1257. doi: 10.1093/emboj/16.6.1248
Europe PMC | doi


1995

Ruigrok RW, Baudin F. (1995)

Structure of influenza virus ribonucleoprotein particles. II. Purified RNA-free influenza virus ribonucleoprotein forms structures that are indistinguishable from the intact influenza virus ribonucleoprotein particles

J. Gen. Virol. 76 ( Pt 4):1009-1014.
Europe PMC


1994

Baudin F, Bach C, Cusack S, Ruigrok RW. (1994)

Structure of influenza virus RNP. I. Influenza virus nucleoprotein melts secondary structure in panhandle RNA and exposes the bases to the solvent

EMBO J. 13(13):3158-3165.
Europe PMC

Elster C, Fourest E, Baudin F, Larsen K, Cusack S, Ruigrok RW. (1994)

A small percentage of influenza virus M1 protein contains zinc but zinc does not influence in vitro M1-RNA interaction

J. Gen. Virol. 75 ( Pt 1):37-42. doi: 10.1099/0022-1317-75-1-37
Europe PMC | doi


1993

Burmeister WP, Baudin F, Cusack S, Ruigrok RW. (1993)

Comparison of structure and sequence of influenza B/Yamagata and B/Beijing neuraminidases shows a conserved "head" but much greater variability in the "stalk" and NB protein

Virology 192(2):683-686. doi: 10.1006/viro.1993.1088
Europe PMC | doi

Baudin F, Marquet R, Isel C, Darlix JL, Ehresmann B, Ehresmann C. (1993)

Functional sites in the 5' region of human immunodeficiency virus type 1 RNA form defined structural domains

J. Mol. Biol. 229(2):382-397. doi: 10.1006/jmbi.1993.1041
Europe PMC | doi


1991

de Stevenson IL, Romby P, Baudin F, Brunel C, Westhof E, Ehresmann C, Ehresmann B, Romaniuk PJ. (1991)

Structural studies on site-directed mutants of domain 3 of Xenopus laevis oocyte 5 S ribosomal RNA.

J. Mol. Biol. 219(2):243-255. doi: 10.1016/0022-2836(91)90565-n
Europe PMC | doi

Marquet R, Baudin F, Gabus C, Darlix JL, Mougel M, Ehresmann C, Ehresmann B. (1991)

Dimerization of human immunodeficiency virus (type 1) RNA: stimulation by cations and possible mechanism.

Nucleic Acids Res. 19(9):2349-2357. doi: 10.1093/nar/19.9.2349
Europe PMC | doi

Baudin F, Romaniuk PJ, Romby P, Brunel C, Westhof E, Ehresmann B, Ehresmann C. (1991)

Involvement of "hinge" nucleotides of Xenopus laevis 5 S rRNA in the RNA structural organization and in the binding of transcription factor TFIIIA.

J. Mol. Biol. 218(1):69-81. doi: 10.1016/0022-2836(91)90874-6
Europe PMC | doi

You QM, Veldhoen N, Baudin F, Romaniuk PJ. (1991)

Mutations in 5S DNA and 5S RNA have different effects on the binding of Xenopus transcription factor IIIA.

Biochemistry 30(9):2495-2500. doi: 10.1021/bi00223a028
Europe PMC | doi


1989

Baudin F, Romby P, Romaniuk PJ, Ehresmann B, Ehresmann C. (1989)

Crosslinking of transcription factor TFIIIA to ribosomal 5S RNA from X. laevis by trans-diamminedichloroplatinum (II).

Nucleic Acids Res. 17(23):10035-10046. doi: 10.1093/nar/17.23.10035
Europe PMC | doi

Romby P, Baudin F, Brunel C, Leal de Stevenson I, Westhof E, Romaniuk PJ, Ehresmann C, Ehresmann B. (1989)

Ribosomal 5S RNA from Xenopus laevis oocytes: conformation and interaction with transcription factor IIIA.

Biochimie 72(6-7):437-452. doi: 10.1016/0300-9084(90)90068-r
Europe PMC | doi

Baudin F, Mougel M, Romby P, Eyermann F, Ebel JP, Ehresmann B, Ehresmann C. (1989)

Probing the phosphates of the Escherichia coli ribosomal 16S RNA in its naked form, in the 30S subunit, and in the 70S ribosome.

Biochemistry 28(14):5847-5855. doi: 10.1021/bi00440a022
Europe PMC | doi

Gornicki P, Baudin F, Romby P, Wiewiorowski M, Kryzosiak W, Ebel JP, Ehresmann C, Ehresmann B. (1989)

Use of lead(II) to probe the structure of large RNA's. Conformation of the 3' terminal domain of E. coli 16S rRNA and its involvement in building the tRNA binding sites.

J. Biomol. Struct. Dyn. 6(5):971-984. doi: 10.1080/07391102.1989.10506525
Europe PMC | doi

Baudin F, Romaniuk PJ. (1989)

A difference in the importance of bulged nucleotides and their parent base pairs in the binding of transcription factor IIIA to Xenopus 5S RNA and 5S RNA genes.

Nucleic Acids Res. 17(5):2043-2056. doi: 10.1093/nar/17.5.2043
Europe PMC | doi


1987

Ehresmann C, Baudin F, Mougel M, Romby P, Ebel JP, Ehresmann B. (1987)

Probing the structure of RNAs in solution.

Nucleic Acids Res. 15(22):9109-9128. doi: 10.1093/nar/15.22.9109
Europe PMC | doi

Baudin F, Ehresmann C, Romby P, Mougel M, Colin J, Lempereur L, Bachellerie JP, Ebel JP, Ehresmann B. (1987)

Higher-order structure of domain III in Escherichia coli 16S ribosomal RNA, 30S subunit and 70S ribosome.

Biochimie 69(10):1081-1096. doi: 10.1016/0300-9084(87)90008-3
Europe PMC | doi