EMBL Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany


  • PhD 2011, EMBL-EBI and Cambridge University.
    Postdoctoral research fellow, Stanford University.
    Group leader at EMBL since 2014.
    Joint appointment with the Genome Biology Unit and with EMBL-EBI.


Total: 11 publication(s)


Ruiz-Velasco M, Kumar M, Lai MC, Bhat P, Solis-Pinson AB, Reyes A, Kleinsorg S, Noh KM, Gibson TJ, Zaugg JB. (2017)

CTCF-Mediated Chromatin Loops between Promoter and Gene Body Regulate Alternative Splicing across Individuals.

Cell Syst doi: 10.1016/j.cels.2017.10.018
Europe PMC | doi

Lai MC, Bechy AL, Denk F, Collins E, Gavriliouk M, Zaugg JB, Ryan BJ, Wade-Martins R, Caffrey TM. (2017)

Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders.

Mol Neurodegener 12(1) doi: 10.1186/s13024-017-0224-6
Europe PMC | doi


Cakiroglu SA, Zaugg JB, Luscombe NM. (2016)

Backmasking in the yeast genome: encoding overlapping information for protein-coding and RNA degradation.

Nucleic Acids Res. 44(17):8065-8072. doi: 10.1093/nar/gkw683
Europe PMC | doi

Arnold C, Bhat P, Zaugg JB. (2016)

SNPhood: investigate, quantify and visualise the epigenomic neighbourhood of SNPs using NGS data.

Bioinformatics 32(15):2359-2360. doi: 10.1093/bioinformatics/btw127
Europe PMC | doi

Ignatiadis N, Klaus B, Zaugg JB, Huber W. (2016)

Data-driven hypothesis weighting increases detection power in genome-scale multiple testing.

Nat. Methods 13(7):577-580. doi: 10.1038/nmeth.3885
Europe PMC | doi

Zaugg LK, Lenherr P, Zaugg JB, Weiger R, Krastl G. (2016)

Influence of the bleaching interval on the luminosity of long-term discolored enamel-dentin discs.

Clin Oral Investig 20(3):451-458. doi: 10.1007/s00784-015-1545-x
Europe PMC | doi


Grubert F, Zaugg JB, Kasowski M, Ursu O, Spacek DV, Martin AR, Greenside P, Srivas R, Phanstiel DH, Pekowska A, Heidari N, Euskirchen G, Huber W, Pritchard JK, Bustamante CD, Steinmetz LM, Kundaje A, Snyder M. (2015)

Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions.

Cell 162(5):1051-1065. doi: 10.1016/j.cell.2015.07.048
Europe PMC | doi


Castelnuovo M, Zaugg JB, Guffanti E, Maffioletti A, Camblong J, Xu Z, Clauder-Münster S, Steinmetz LM, Luscombe NM, Stutz F. (2014)

Role of histone modifications and early termination in pervasive transcription and antisense-mediated gene silencing in yeast.

Nucleic Acids Res. 42(7):4348-4362. doi: 10.1093/nar/gku100
Europe PMC | doi


Kasowski M, Kyriazopoulou-Panagiotopoulou S, Grubert F, Zaugg JB, Kundaje A, Liu Y, Boyle AP, Zhang QC, Zakharia F, Spacek DV, Li J, Xie D, Olarerin-George A, Steinmetz LM, Hogenesch JB, Kellis M, Batzoglou S, Snyder M. (2013)

Extensive variation in chromatin states across humans

Science 342(6159):750-752. doi: 10.1126/science.1242510
Europe PMC | doi


Tan-Wong SM, Zaugg JB, Camblong J, Xu Z, Zhang DW, Mischo HE, Ansari AZ, Luscombe NM, Steinmetz LM, Proudfoot NJ. (2012)

Gene loops enhance transcriptional directionality

Science 338(6107):671-675. doi: 10.1126/science.1224350
Europe PMC | doi

Zaugg JB, Luscombe NM. (2012)

A genomic model of condition-specific nucleosome behavior explains transcriptional activity in yeast

Genome Res. 22(1):84-94. doi: 10.1101/gr.124099.111
Europe PMC | doi