The Advanced Light Microscopy Facility (ALMF) offers a collection of state-of-the-art light microscopy equipment and image processing tools.
The facility was set up as a cooperation between EMBL and industry to improve communication between users and producers of high-end microscopy technology. The ALMF supports in-house scientists and visitors in using light microscopy methods for their research. The ALMF also regularly organises in-house and international courses to teach basic and advanced light microscopy methods.
Major projects and accomplishments
- The ALMF currently manages 20 advanced microscope systems and 10 high-content microscopes from leading industrial companies.
- Several workstations for image analysis are provided.
- More than 50 visitors per year come to carry out their own experiments in the ALMF or to evaluate microscopy equipment.
- The ALMF was the seed for the European Light Microscopy Initiative (ELMI) that establishes links between core facilities, users and industry throughout Europe.
- A number of Proof-of-Concept studies have been hosted in the framework of Eurobioimaging.
- 5 genome wide screens were supported by the ALMF.
- Usage of the facility has exceeded 50,000 hours per year.
- Project planning, sample preparation, microscope selection and use, image processing and visualization.
- Support of advanced microscopy techniques e.g. FRAP, FRET, FCS, laser nanosurgery and super-resolution.
- Developing accessory software and microscopy equipment, co-developments with industrial partners, pre-evaluation of commercial equipment.
- Supporting all aspects of automated microscopy and high-throughput microscopy projects, including RNAi technology.
- Image and data analysis for light microscopy
The ALMF collaborates with a number of technology partners.