Total: 94 publication(s)


Custódio TF, Das H, Sheward DJ, Hanke L, Pazicky S, Pieprzyk J, Sorgenfrei M, Schroer MA, Gruzinov AY, Jeffries CM, Graewert MA, Svergun DI, Dobrev N, Remans K, Seeger MA, McInerney GM, Murrell B, Hällberg BM, Löw C. (2020)

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.

Nat Commun 11(1) doi: 10.1038/s41467-020-19204-y
Europe PMC | doi

Bonfiglio JJ, Leidecker O, Dauben H, Longarini EJ, Colby T, San Segundo-Acosta P, Perez KA, Matic I. (2020)

An HPF1/PARP1-based chemical biology strategy for exploring ADP-ribosylation.

Cell 183(4):1086-1102.e23. doi: 10.1016/j.cell.2020.09.055
Europe PMC | doi

Bourdeaux F, Kopp Y, Lautenschläger J, Gößner I, Besir H, Vabulas RM, Grininger M. (2020)

Dodecin as carrier protein for immunizations and bioengineering applications.

Sci Rep 10(1) doi: 10.1038/s41598-020-69990-0
Europe PMC | doi

Camacho E, Rucavado A, Escalante T, Gutiérrez JM, Remans K. (2020)

Substitutions of residues in a loop surrounding the active site of a P-I snake venom metalloproteinase abrogates its hemorrhagic activity.

Toxicon 177 Suppl 1 doi: 10.1016/j.toxicon.2019.12.123
Europe PMC | doi

Chen PC, Masiewicz P, Perez K, Hennig J. (2020)

Structure-based screening of binding affinities via small-angle X-ray scattering.

IUCrJ 7(Pt 4):644-655. doi: 10.1107/S2052252520004169
Europe PMC | doi


Uebel S, de Marco A, Berrow N, Lebendiker M, Garcia-Alai M, Knauer SH, Lopez-Mendez B, Matagne A, Parret A, Remans K, Raynal B. (2019)

Quality control of purified proteins to improve research data reproducibility.

J Biomol Tech 30(Suppl)
Europe PMC

Camacho E, Escalante T, Remans K, Gutiérrez JM, Rucavado A. (2019)

Site mutation of residues in a loop surrounding the active site of a PI snake venom metalloproteinase abrogates its hemorrhagic activity.

Biochem. Biophys. Res. Commun. 512(4):859-863. doi: 10.1016/j.bbrc.2019.03.152
Europe PMC | doi


Stolt-Bergner P, Benda C, Bergbrede T, Besir H, Celie PHN, Chang C, Drechsel D, Fischer A, Geerlof A, Giabbai B, van den Heuvel J, Huber G, Knecht W, Lehner A, Lemaitre R, Nordén K, Pardee G, Racke I, Remans K, Sander A, Scholz J, Stadnik M, Storici P, Weinbruch D, Zaror I, Lua LHL, Suppmann S. (2018)

Baculovirus-driven protein expression in insect cells: a benchmarking study.

J. Struct. Biol. 203(2):71-80. doi: 10.1016/j.jsb.2018.03.004
Europe PMC | doi

Chen PC, Masiewicz P, Rybin V, Svergun D, Hennig J. (2018)

A general small-angle X-ray scattering-based screening protocol validated for protein-RNA interactions.

ACS Comb Sci 20(4) doi: 10.1021/acscombsci.8b00007
Europe PMC | doi

Martin P, Palhière I, Maroteau C, Bardou P, Canale-Tabet K, Sarry J, Woloszyn F, Bertrand-Michel J, Racke I, Besir H, Rupp R, Tosser-Klopp G. (2018)

Author Correction: A genome scan for milk production traits in dairy goats reveals two new mutations in Dgat1 reducing milk fat content.

Sci Rep. 8(1) doi: 10.1038/s41598-018-22118-x
Europe PMC | doi

Hennig BP, Velten L, Racke I, Szu Tu C, Thoms M, Rybin V, Besir H, Remans K, Steinmetz LM. (2018)

Large-scale low-cost NGS library preparation using a robust Tn5 purification and tagmentation protocol.

G3 (Bethesda) 8(1) doi: 10.1534/g3.117.300257
Europe PMC | doi


Kschonsak M, Merkel F, Bisht S, Metz J, Rybin V, Hassler M, Haering CH. (2017)

Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.

Cell 171(3):588-600. doi: 10.1016/j.cell.2017.09.008
Europe PMC | doi

Schulz EC, Seiler M, Zuliani C, Voigt F, Rybin V, Pogenberg V, Mücke N, Wilmanns M, Gibson TJ, Barabas O.. (2017)

Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq

Sci Rep 7(1):9903. doi: 10.1038/s41598-017-10085-8
Europe PMC | doi

Martin P, Palhière I, Maroteau C, Bardou P, Canale-Tabet K, Sarry J, Woloszyn F, Bertrand-Michel J, Racke I, Besir H, Rupp R, Tosser-Klopp G. (2017)

A genome scan for milk production traits in dairy goats reveals two new mutations in Dgat1 reducing milk fat content.

Sci Rep 7(1872):1-13. doi: 10.1038/s41598-017-02052-0
Europe PMC | doi

Besir H. (2017)

A Generic Protocol for Purifying Disulfide-Bonded Domains and Random Protein Fragments Using Fusion Proteins with SUMO3 and Cleavage by SenP2 Protease.

Methods Mol. Biol. 1586:141-154. doi: 10.1007/978-1-4939-6887-9_9
Europe PMC | doi


Miller TC, Simon B, Rybin V, Grötsch H, Curtet S, Khochbin S, Carlomagno T, Müller CW. (2016)

A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT

Nat Commun 7:13855. doi: 10.1038/ncomms13855
Europe PMC | doi

Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, Landry JJ, Fritz MH, Radic K, Hoffmann JE, Chen ZA, Zou J, Tan PS, Galik B, Junttila S, Stolt-Bergner P, Pruneri G, Gyenesei A, Schultz C, Biskup MB, Besir H, Benes V, Rappsilber J, Jechlinger M, Korbel JO, Berger I, Braese S, Lemke EA. (2016)

Genetic code expansion for multiprotein complex engineering.

Nat. Methods 13(12) doi: 10.1038/nmeth.4032
Europe PMC | doi

Gerner L, Munack S, Temmerman K, Lawrence-Dærner A, Besir H, Wilmanns M, Jensen JK, Thiede B, Mills IG, Morth JP. (2016)

Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2

Biochem. Biophys. Res. Commun. 476(2):102-107. doi: 10.1016/j.bbrc.2016.05.045
Europe PMC | doi

Gerner L, Munack S, Temmerman K, Lawrence-Dörner AM, Besir H, Wilmanns M, Jensen JK, Thiede B, Mills IG, Morth JP. (2016)

Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli.

Data Brief 8:733-740. doi: 10.1016/j.dib.2016.06.033
Europe PMC | doi

Parret AH, Besir H, Meijers R. (2016)

Critical reflections on synthetic gene design for recombinant protein expression.

Curr. Opin. Struct. Biol. 38:155-162. doi: 10.1016/
Europe PMC | doi


Vonkova I, Saliba AE, Deghou S, Anand K, Ceschia S, Doerks T, Galih A, Kugler KG, Maeda K, Rybin V, van Noort V, Ellenberg J, Bork P, Gavin AC. (2015)

Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains.

Cell Rep 12(9):1519-1530. doi: 10.1016/j.celrep.2015.07.054
Europe PMC | doi

Bleckmann M, Fritz MHY, Bhuju S, Jarek M, Schurig M, Geffers R, Benes V, Besir H, van den Heuvel J. (2015)

Genomic Analysis and Isolation of RNA Polymerase II Dependent Promoters from Spodoptera frugiperda

PLoS One 10(8):e0132898. doi: 10.1371/journal.pone.0132898
Europe PMC | doi

Jeske M, Bordi M, Glatt S, Müller S, Rybin V, Müller CW, Ephrussi A. (2015)

The crystal structure of the Drosophila germline inducer oskar identifies two domains with distinct Vasa helicase- and RNA-binding activities.

Cell Rep 12(4):1-12. doi: 10.1016/j.celrep.2015.06.055
Europe PMC | doi

Skruzny M, Desfosses A, Prinz S, Dodonova SO, Gieras A, Uetrecht C, Jakobi AJ, Abella M, Hagen WJ, Schulz J, Meijers R, Rybin V, Briggs JA, Sachse C, Kaksonen M. (2015)

An Organized Co-assembly of Clathrin Adaptors Is Essential for Endocytosis.

Dev. Cell 33(2):150-162. doi: 10.1016/j.devcel.2015.02.023
Europe PMC | doi

Glatt S, Zabel R, Vonkova I, Kumar A, Netz DJ, Pierik AJ, Rybin V, Lill R, Gavin A, Balbach J, Breunig KD, Müller CW. (2015)

Structure of the Kti11/Kti13 Heterodimer and Its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.

Structure 23(1):149-160. doi: 10.1016/j.str.2014.11.008
Europe PMC | doi


Bojar D, Martinez J, Santiago J, Rybin V, Bayliss R, Hothorn M. (2014)

Crystal structures of the phosphorylated BRI1 kinase domain and implications for brassinosteroid signal initiation.

Plant J. 78(1):31-43. doi: 10.1111/tpj.12445
Europe PMC | doi


Costa SJ, Almeida A, Castro A, Domingues L, Besir H. (2013)

The novel Fh8 and H fusion partners for soluble protein expression in Escherichia coli: a comparison with the traditional gene fusion technology

Appl. Microbiol. Biotechnol. 97(15):6779-6791. doi: 10.1007/s00253-012-4559-1
Europe PMC | doi

Hondele M, Stuwe T, Hassler M, Halbach F, Bowman A, Zhang ET, Nijmeijer B, Kotthoff C, Rybin V, Amlacher S, Hurt E, Ladurner AG. (2013)

Structural basis of histone H2A-H2B recognition by the essential chaperone FACT

Nature 499(7456):111-114. doi: 10.1038/nature12242
Europe PMC | doi

Taylor NM, Glatt S, Hennrich ML, von Scheven G, Grötsch H, Fernández-Tornero C, Rybin V, Gavin AC, Kolb P, Müller CW. (2013)

Structural and functional characterization of a phosphatase domain within yeast general transcription factor IIIC

J. Biol. Chem. 288(21):15110-15120. doi: 10.1074/jbc.m112.427856
Europe PMC | doi

Jankevicius G, Hassler M, Golia B, Rybin V, Zacharias M, Timinszky G, Ladurner AG. (2013)

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation

Nat. Struct. Mol. Biol. 20(4):508-514. doi: 10.1038/nsmb.2523
Europe PMC | doi

Scholz J, Besir H, Strasser C, Suppmann S. (2013)

A new method to customize protein expression vectors for fast, efficient and background free parallel cloning

BMC Biotechnol. 13:12. doi: 10.1186/1472-6750-13-12
Europe PMC | doi

Ventura E, Riondato M, Sambuceti G, Salis A, Damonte G, Cordazzo C, Besir H, Pistoia V, Zardi L. (2013)

Use of the uteroglobin platform for the expression of a bivalent antibody against oncofetal fibronectin in Escherichia coli

PLoS ONE 8(12):e82878. doi: 10.1371/journal.pone.0082878
Europe PMC | doi


Zanier K, ould M'hamed ould Sidi A, Boulade-Ladame C, Rybin V, Chappelle A, Atkinson A, Kieffer B, Travé G. (2012)

Solution structure analysis of the HPV16 E6 oncoprotein reveals a self-association mechanism required for E6-mediated degradation of p53

Structure 20(4):604-617. doi: 10.1016/j.str.2012.02.001
Europe PMC | doi

Gjerstorff MF, Rösner HI, Pedersen CB, Greve KB, Schmidt S, Wilson KL, Mollenhauer J, Besir H, Poulsen FM, Møllegaard NE, Ditzel HJ. (2012)

GAGE cancer-germline antigens are recruited to the nuclear envelope by germ cell-less (GCL)

PLoS ONE 7(9):e45819. doi: 10.1371/journal.pone.0045819
Europe PMC | doi

Schlesner M, Miller A, Besir H, Aivaliotis M, Streif J, Scheffer B, Siedler F, Oesterhelt D. (2012)

The protein interaction network of a taxis signal transduction system in a halophilic archaeon

BMC Microbiol. 12:272. doi: 10.1186/1471-2180-12-272
Europe PMC | doi

van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC. (2012)

Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium

Mol. Syst. Biol. 8:571. doi: 10.1038/msb.2012.4
Europe PMC | doi


Bayer-Giraldi M, Weikusat I, Besir H, Dieckmann G. (2011)

Characterization of an antifreeze protein from the polar diatom Fragilariopsis cylindrus and its relevance in sea ice

Cryobiology 63(3):210-219. doi: 10.1016/j.cryobiol.2011.08.006
Europe PMC | doi

Duszczyk MM, Wutz A, Rybin V, Sattler M. (2011)

The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization

RNA 17(11):1973-1982. doi: 10.1261/rna.2747411
Europe PMC | doi

Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcárcel J, Sattler M. (2011)

Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF

Nature 475(7356):408-411. doi: 10.1038/nature10171
Europe PMC | doi

Nowak AJ, Alfieri C, Stirnimann CU, Rybin V, Baudin F, Ly-Hartig N, Lindner D, Müller CW. (2011)

Chromatin-modifying complex component Nurf55/p55 associates with histones H3 and H4 and polycomb repressive complex 2 subunit Su(z)12 through partially overlapping binding sites

J. Biol. Chem. 286(26):23388-23396. doi: 10.1074/jbc.m110.207407
Europe PMC | doi

Langer K, Dian C, Rybin V, Müller CW, Petosa C. (2011)

Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain

PLoS ONE 6(2):e17011. doi: 10.1371/journal.pone.0017011
Europe PMC | doi


Gallego O, Betts MJ, Gvozdenovic-Jeremic J, Maeda K, Matetzki C, Aguilar-Gurrieri C, Beltran-Alvarez P, Bonn S, Fernández-Tornero C, Jensen LJ, Kuhn M, Trott J, Rybin V, Müller CW, Bork P, Kaksonen M, Russell RB, Gavin AC. (2010)

A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae

Mol. Syst. Biol. 6:430. doi: 10.1038/msb.2010.87
Europe PMC | doi

Gjerstorff MF, Besir H, Larsen MR, Ditzel HJ. (2010)

Expression, purification and characterization of the cancer-germline antigen GAGE12I: a candidate for cancer immunotherapy

Protein Expr. Purif. 73(2):217-222. doi: 10.1016/j.pep.2010.05.010
Europe PMC | doi

Hothorn M, Van den Ende W, Lammens W, Rybin V, Scheffzek K. (2010)

Structural insights into the pH-controlled targeting of plant cell-wall invertase by a specific inhibitor protein

Proc. Natl. Acad. Sci. U.S.A. 107(40):17427-17432. doi: 10.1073/pnas.1004481107
Europe PMC | doi

Wirtz M, Birke H, Heeg C, Müller C, Hosp F, Throm C, König S, Feldman-Salit A, Rippe K, Petersen G, Wade RC, Rybin V, Scheffzek K, Hell R. (2010)

Structure and function of the hetero-oligomeric cysteine synthase complex in plants

J. Biol. Chem. 285(43):32810-32817. doi: 10.1074/jbc.m110.157446
Europe PMC | doi

Schallus T, Fehér K, Sternberg U, Rybin V, Muhle-Goll C. (2010)

Analysis of the specific interactions between the lectin domain of malectin and diglucosides

Glycobiology 20(8):1010-1020. doi: 10.1093/glycob/cwq059
Europe PMC | doi

Stankiewicz M, Nikolay R, Rybin V, Mayer MP. (2010)

CHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substrates

FEBS J. 277(16):3353-3367. doi: 10.1111/j.1742-4658.2010.07737.x
Europe PMC | doi

Eder M, Knackmuss S, Le Gall F, Reusch U, Rybin V, Little M, Haberkorn U, Mier W, Eisenhut M. (2010)

68Ga-labelled recombinant antibody variants for immuno-PET imaging of solid tumours

Eur. J. Nucl. Med. Mol. Imaging 37(7):1397-1407. doi: 10.1007/s00259-010-1392-6
Europe PMC | doi

Krzic U, Rybin V, Leonard KR, Linke WA, Bullard B. (2010)

Regulation of oscillatory contraction in insect flight muscle by troponin

J. Mol. Biol. 397(1):110-118. doi: 10.1016/j.jmb.2010.01.039
Europe PMC | doi

Zanier K, Ruhlmann C, Melin F, Masson M, Ould M'hamed Ould Sidi A, Bernard X, Fischer B, Brino L, Ristriani T, Rybin V, Baltzinger M, Vande Pol S, Hellwig P, Schultz P, Travé G. (2010)

E6 proteins from diverse papillomaviruses self-associate both in vitro and in vivo

J. Mol. Biol. 396(1):90-104. doi: 10.1016/j.jmb.2009.11.022
Europe PMC | doi


Kühner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castaño-Diez D, Chen WH, Devos D, Güell M, Norambuena T, Racke I, Rybin V, Schmidt A, Yus E, Aebersold R, Herrmann R, Böttcher B, Frangakis AS, Russell RB, Serrano L, Bork P, Gavin AC. (2009)

Proteome organization in a genome-reduced bacterium

Science 326(5957):1235-1240. doi: 10.1126/science.1176343
Europe PMC | doi

Van Doorslaer K, Sidi AO, Zanier K, Rybin V, Deryckère F, Rector A, Burk RD, Lienau EK, van Ranst M, Travé G. (2009)

Identification of unusual E6 and E7 proteins within avian papillomaviruses: cellular localization, biophysical characterization, and phylogenetic analysis

J. Virol. 83(17):8759-8770. doi: 10.1128/jvi.01777-08
Europe PMC | doi

Grimm C, Matos R, Ly-Hartig N, Steuerwald U, Lindner D, Rybin V, Müller J, Müller CW. (2009)

Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt

EMBO J. 28(13):1965-1977. doi: 10.1038/emboj.2009.147
Europe PMC | doi

McGillicuddy LT, Fromm JA, Hollstein PE, Kubek S, Beroukhim R, De Raedt T, Johnson BW, Williams SM, Nghiemphu P, Liau LM, Cloughesy TF, Mischel PS, Parret A, Seiler J, Moldenhauer G, Scheffzek K, Stemmer-Rachamimov AO, Sawyers CL, Brennan C, Messiaen L, Mellinghoff IK, Cichowski K. (2009)

Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis

Cancer Cell 16(1):44-54. doi: 10.1016/j.ccr.2009.05.009
Europe PMC | doi

Hothorn M, Neumann H, Lenherr ED, Wehner M, Rybin V, Hassa PO, Uttenweiler A, Reinhardt M, Schmidt A, Seiler J, Ladurner AG, Herrmann C, Scheffzek K, Mayer A. (2009)

Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase

Science 324(5926):513-516. doi: 10.1126/science.1168120
Europe PMC | doi

Ami D, Natalello A, Schultz T, Gatti-Lafranconi P, Lotti M, Doglia SM, de Marco A. (2009)

Effects of recombinant protein misfolding and aggregation on bacterial membranes

Biochim. Biophys. Acta 1794(2):263-269. doi: 10.1016/j.bbapap.2008.10.015
Europe PMC | doi

Kuehnel MP, Rybin V, Anand PK, Anes E, Griffiths G. (2009)

Lipids regulate P2X7-receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen

J. Cell. Sci. 122(Pt 4):499-504. doi: 10.1242/jcs.034199
Europe PMC | doi

Corsini L, Hothorn M, Stier G, Rybin V, Scheffzek K, Gibson TJ, Sattler M. (2009)

Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60

J. Biol. Chem. 284(1):630-639. doi: 10.1074/jbc.m805395200
Europe PMC | doi

Lawrence AM, Besir HU. (2009)

Staining of proteins in gels with Coomassie G-250 without organic solvent and acetic acid

J Vis Exp (30):351-356. doi: 10.3791/1350
Europe PMC | doi


Stuwe T, Hothorn M, Lejeune E, Rybin V, Bortfeld M, Scheffzek K, Ladurner AG. (2008)

The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module

Proc. Natl. Acad. Sci. U.S.A. 105(26):8884-8889. doi: 10.1073/pnas.0712293105
Europe PMC | doi

Gromes R, Hothorn M, Lenherr ED, Rybin V, Scheffzek K, Rausch T. (2008)

The redox switch of gamma-glutamylcysteine ligase via a reversible monomer-dimer transition is a mechanism unique to plants

Plant J. 54(6):1063-1075. doi: 10.1111/j.1365-313x.2008.03477.x
Europe PMC | doi

Fiedler M, Sánchez-Barrena MJ, Nekrasov M, Mieszczanek J, Rybin V, Müller J, Evans P, Bienz M. (2008)

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex

Mol. Cell 30(4):507-518. doi: 10.1016/j.molcel.2008.03.011
Europe PMC | doi

Natalello A, Santarella R, Doglia SM, de Marco A. (2008)

Physical and chemical perturbations induce the formation of protein aggregates with different structural features

Protein Expr. Purif. 58(2):356-361. doi: 10.1016/j.pep.2007.12.002
Europe PMC | doi

Koyama S, Hata S, Witt CC, Ono Y, Lerche S, Ojima K, Chiba T, Doi N, Kitamura F, Tanaka K, Abe K, Witt SH, Rybin V, Gasch A, Franz T, Labeit S, Sorimachi H. (2008)

Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis

J. Mol. Biol. 376(5):1224-1236. doi: 10.1016/j.jmb.2007.11.049
Europe PMC | doi

Denayer E, Parret A, Chmara M, Schubbert S, Vogels A, Devriendt K, Frijns JP, Rybin V, de Ravel TJ, Shannon K, Cools J, Scheffzek K, Legius E. (2008)

Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation

Hum. Mutat. 29(2):232-239. doi: 10.1002/humu.20616
Europe PMC | doi


Grimm C, de Ayala Alonso AG, Rybin V, Steuerwald U, Ly-Hartig N, Fischle W, Müller J, Müller CW. (2007)

Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

EMBO Rep. 8(11):1031-1037. doi: 10.1038/sj.embor.7401085
Europe PMC | doi

Sjekloća L, Pudas R, Sjöblom B, Konarev P, Carugo O, Rybin V, Kiema TR, Svergun D, Ylänne J, Djinović Carugo K. (2007)

Crystal structure of human filamin C domain 23 and small angle scattering model for filamin C 23-24 dimer

J. Mol. Biol. 368(4):1011-1023. doi: 10.1016/j.jmb.2007.02.018
Europe PMC | doi

Oddone A, Lorentzen E, Basquin J, Gasch A, Rybin V, Conti E, Sattler M. (2007)

Structural and biochemical characterization of the yeast exosome component Rrp40

EMBO Rep. 8(1):63-69. doi: 10.1038/sj.embor.7400856
Europe PMC | doi


Kalamidas SA, Kuehnel MP, Peyron P, Rybin V, Rauch S, Kotoulas OB, Houslay M, Hemmings BA, Gutierrez MG, Anes E, Griffiths G. (2006)

cAMP synthesis and degradation by phagosomes regulate actin assembly and fusion events: consequences for mycobacteria

J. Cell. Sci. 119(Pt 17):3686-3694. doi: 10.1242/jcs.03091
Europe PMC | doi

Boyault C, Gilquin B, Zhang Y, Rybin V, Garman E, Meyer-Klaucke W, Matthias P, Müller CW, Khochbin S. (2006)

HDAC6-p97/VCP controlled polyubiquitin chain turnover

EMBO J. 25(14):3357-3366. doi: 10.1038/sj.emboj.7601210
Europe PMC | doi

Pastore C, Adinolfi S, Huynen MA, Rybin V, Martin S, Mayer M, Bukau B, Pastore A. (2006)

YfhJ, a molecular adaptor in iron-sulfur cluster formation or a frataxin-like protein?

Structure 14(5):857-867. doi: 10.1016/j.str.2006.02.010
Europe PMC | doi

Gareus R, Di Nardo A, Rybin V, Witke W. (2006)

Mouse profilin 2 regulates endocytosis and competes with SH3 ligand binding to dynamin 1

J. Biol. Chem. 281(5):2803-2811. doi: 10.1074/jbc.m503528200
Europe PMC | doi

Schultz T, Martinez L, de Marco A. (2006)

The evaluation of the factors that cause aggregation during recombinant expression in E. coli is simplified by the employment of an aggregation-sensitive reporter

Microb. Cell Fact. 5:28. doi: 10.1186/1475-2859-5-28
Europe PMC | doi


Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M. (2005)

Substrate access to the active sites in aminopeptidase T, a representative of a new metallopeptidase clan

J. Mol. Biol. 354(2):403-412. doi: 10.1016/j.jmb.2005.09.042
Europe PMC | doi

Franz C, Askjaer P, Antonin W, Iglesias CL, Haselmann U, Schelder M, de Marco A, Wilm M, Antony C, Mattaj IW. (2005)

Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates

EMBO J. 24(20):3519-3531. doi: 10.1038/sj.emboj.7600825
Europe PMC | doi

Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M. (2005)

Staphylococcus aureus aminopeptidase S is a founding member of a new peptidase clan

J. Biol. Chem. 280(30):27792-27799. doi: 10.1074/jbc.m502023200
Europe PMC | doi

de Marco A, Vigh L, Diamant S, Goloubinoff P. (2005)

Native folding of aggregation-prone recombinant proteins in Escherichia coli by osmolytes, plasmid- or benzyl alcohol-overexpressed molecular chaperones

Cell Stress Chaperones 10(4):329-339. doi: 10.1379/CSC-139R.1
Europe PMC | doi

Dümmler A, Lawrence AM, de Marco A. (2005)

Simplified screening for the detection of soluble fusion constructs expressed in E. coli using a modular set of vectors

Microb. Cell Fact. 4:34. doi: 10.1186/1475-2859-4-34
Europe PMC | doi


De Marco V, Stier G, Blandin S, de Marco A. (2004)

The solubility and stability of recombinant proteins are increased by their fusion to NusA

Biochem. Biophys. Res. Commun. 322(3):766-771. doi: 10.1016/j.bbrc.2004.07.189
Europe PMC | doi

de Marco A, Casatta E, Savaresi S, Geerlof A. (2004)

Recombinant proteins fused to thermostable partners can be purified by heat incubation

J. Biotechnol. 107(2):125-133. doi: 10.1016/j.jbiotec.2003.10.008
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Reina J, Lacroix E, Hobson SD, Fernandez-Ballester G, Rybin V, Schwab MS, Serrano L, Gonzalez C. (2002)

Computer-aided design of a PDZ domain to recognize new target sequences

Nat. Struct. Biol. 9(8):621-627. doi: 10.1038/nsb815
Europe PMC | doi

Defacque H, Bos E, Garvalov B, Barret C, Roy C, Mangeat P, Shin HW, Rybin V, Griffiths G. (2002)

Phosphoinositides regulate membrane-dependent actin assembly by latex bead phagosomes

Mol. Biol. Cell 13(4):1190-1202. doi: 10.1091/mbc.01-06-0314
Europe PMC | doi

Gavin AC, Bösche M, Krause R, Grandi P, Marzioch M, Bauer A, Schultz J, Rick JM, Michon AM, Cruciat CM, Remor M, Höfert C, Schelder M, Brajenovic M, Ruffner H, Merino A, Klein K, Hudak M, Dickson D, Rudi T, Gnau V, Bauch A, Bastuck S, Huhse B, Leutwein C, Heurtier MA, Copley RR, Edelmann A, Querfurth E, Rybin V, Drewes G, Raida M, Bouwmeester T, Bork P, Seraphin B, Kuster B, Neubauer G, Superti-Furga G. (2002)

Functional organization of the yeast proteome by systematic analysis of protein complexes

Nature 415(6868):141-147. doi: 10.1038/415141a
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Lippé R, Miaczynska M, Rybin V, Runge A, Zerial M. (2001)

Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex

Mol. Biol. Cell 12(7):2219-2228. doi: 10.1091/mbc.12.7.2219
Europe PMC | doi

Esters H, Alexandrov K, Iakovenko A, Ivanova T, Thomä N, Rybin V, Zerial M, Scheidig AJ, Goody RS. (2001)

Vps9, Rabex-5 and DSS4: proteins with weak but distinct nucleotide-exchange activities for Rab proteins

J. Mol. Biol. 310(1):141-156. doi: 10.1006/jmbi.2001.4735
Europe PMC | doi

Jahraus A, Egeberg M, Hinner B, Habermann A, Sackman E, Pralle A, Faulstich H, Rybin V, Defacque H, Griffiths G. (2001)

ATP-dependent membrane assembly of F-actin facilitates membrane fusion

Mol. Biol. Cell 12(1):155-170. doi: 10.1091/mbc.12.1.155
Europe PMC | doi


Lanzetti L, Rybin V, Malabarba MG, Christoforidis S, Scita G, Zerial M, Di Fiore PP. (2000)

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

Nature 408(6810):374-377. doi: 10.1038/35042605
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McCarthy AA, Haebel PW, Törrönen A, Rybin V, Baker EN, Metcalf P. (2000)

Crystal structure of the protein disulfide bond isomerase, DsbC, from Escherichia coli

Nat. Struct. Biol. 7(3):196-199. doi: 10.1038/73295
Europe PMC | doi


McBride HM, Rybin V, Murphy C, Giner A, Teasdale R, Zerial M. (1999)

Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13

Cell 98(3):377-386. doi: 10.1016/s0092-8674(00)81966-2
Europe PMC | doi


Gournier H, Stenmark H, Rybin V, Lippé R, Zerial M. (1998)

Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion

EMBO J. 17(7):1930-1940. doi: 10.1093/emboj/17.7.1930
Europe PMC | doi

Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M. (1998)

Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5

EMBO J. 17(7):1941-1951. doi: 10.1093/emboj/17.7.1941
Europe PMC | doi


Horiuchi H, Lippé R, McBride HM, Rubino M, Woodman P, Stenmark H, Rybin V, Wilm M, Ashman K, Mann M, Zerial M. (1997)

A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function

Cell 90(6):1149-1159. doi: 10.1016/s0092-8674(00)80380-3
Europe PMC | doi


Murphy C, Saffrich R, Grummt M, Gournier H, Rybin V, Rubino M, Auvinen P, Lütcke A, Parton RG, Zerial M. (1996)

Endosome dynamics regulated by a Rho protein

Nature 384(6608):427-432. doi: 10.1038/384427a0
Europe PMC | doi

Rybin V, Ullrich O, Rubino M, Alexandrov K, Simon I, Seabra MC, Goody R, Zerial M. (1996)

GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

Nature 383(6597):266-269. doi: 10.1038/383266a0
Europe PMC | doi