Total: 19 publications

2019

Abdelkareem M, Saint-André C, Takacs M, Papai G, Crucifix C, Guo X, Ortiz J, Weixlbaumer A. (2019)
Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation
Mol Cell. S1097-2765(19)30321-1 doi: 10.1016/j.molcel.2019.04.029

Qi C, Sorrentino S, Medalia O, Korkhov VM. (2019)
The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein
Science 364(6438): 389-394 doi: 10.1126/science.aav0778

Radamaker L, Lin YH, Annamalai K, Huhn S, Hegenbart U, Schönland SO, Fritz G, Schmidt M, Fändrich M. (2019)
Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis.
Nat Commun. 10 (1):1103 doi: 10.1038/s41467-019-09032-0

Liberta F, Loerch S, Rennegarbe M, Schierhorn A, Westermark P, Westermark GT, Hazenberg BPC, Grigorieff N, Fändrich M, Schmidt M. (2019)
Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids
Nat Commun. 10 (1):1104. doi:10.1038/s41467-019-09033-z

2018

Weis F, Menting JG, Margetts MB, Chan SJ, Xu Y, Tennagels N, Wohlfart P, Langer T, Müller CW, Dreyer MK, Lawrence MC. (2018)
The signalling conformation of the insulin receptor ectodomain.
Nat Commun. 9(1):4420. doi: 10.1038/s41467-018-06826-6

Zivanov J, Nakane T, Forsberg BO, Kimanius D, Hagen WJ, Lindahl E, Scheres SH. (2018)
New tools for automated high-resolution cryo-EM structure determination in RELION-3.
Elife. 7. pii: e42166. doi: 10.7554/eLife.42166

Oosterheert W, van Bezouwen LS, Rodenburg RNP, Granneman J, Förster F, Mattevi A, Gros P. (2018)
Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction.
Nat Commun. 9(1):4337. doi: 10.1038/s41467-018-06817-7

Hutchings J, Stancheva V, Miller EA, Zanetti G. (2018)
Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape.
Nat Commun. 9(1):4154. doi: 10.1038/s41467-018-06577-4

Vorländer MK, Khatter H, Wetzel R, Hagen WJH, Müller CW. (2018)
Molecular mechanism of promoter opening by RNA polymerase III.
Nature 553(7688):295-300. doi: 10.1038/nature25440

Abascal-Palacios G, Ramsay EP, Beuron F, Morris E, Vannini A. (2018)
Structural basis of RNA polymerase III transcription initiation.
Nature 553(7688):301-306. doi: 10.1038/nature25441

2017

Sadian Y, Tafur L, Kosinski J, Jakobi AJ, Wetzel R, Buczak K, Hagen WJ, Beck M, Sachse C, Müller CW. (2017)
Structural insights into transcription initiation by yeast RNA polymerase I.
EMBO J. 36(18):2698-2709. doi: 10.15252/embj.201796958

Alewijnse B, Ashton AW, Chambers MG, Chen S, Cheng A, Ebrahim M, Eng ET, Hagen WJH, Koster AJ, López CS, Lukoyanova N, Ortega J, Renault L, Reyntjens S, Rice WJ, Scapin G, Schrijver R, Siebert A, Stagg SM, Grum-Tokars V, Wright ER, Wu S, Yu Z, Zhou ZH, Carragher B, Potter CS. (2017)
Best practices for managing large CryoEM facilities.
J Struct Biol. 199(3):225-236. doi: 10.1016/j.jsb.2017.07.011

Hagen WJH1, Wan W1, Briggs JAG2. (2017)
Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging.
J Struct Biol. 197(2):191-198. doi: 10.1016/j.jsb.2016.06.007

Bharat TAM, Kureisaite-Ciziene D, Hardy GG, Yu EW, Devant JM, Hagen WJH, Brun YV, Briggs JAG, Löwe J. (2017)
Structure of the hexagonal surface layer on Caulobacter crescentus cells.
Nat Microbiol 2. doi: 10.1038/nmicrobiol.2017.59

2016

Tafur L, Sadian Y, Hoffmann NA, Jakobi AJ, Wetzel R, Hagen WJ, Sachse C, Müller CW. (2016)
Molecular Structures of Transcribing RNA Polymerase I.
Mol Cell. 64(6):1135-1143. doi: 10.1016/j.molcel.2016.11.013

Mattei S, Glass B, Hagen WJ, Kräusslich HG, Briggs JA. (2016)
The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science 354(6318):1434-1437. doi: 10.1126/science.aah4972

Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuilio AL, Wan W, Bui KH, Hagen WJ, Briggs JA, Glavy JS, Hurt E, Beck M. (2016)
Molecular architecture of the inner ring scaffold of the human nuclear pore complex.
Science 352(6283):363-365. doi: 10.1126/science.aaf0643

Schur FK, Obr M, Hagen WJ, Wan W, Jakobi AJ, Kirkpatrick JM, Sachse C, Kräusslich HG, Briggs JA. (2016)
An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation.
Science 353(6298):506-508. doi: 10.1126/science.aaf9620

Bertipaglia C, Schneider S, Jakobi AJ, Tarafder AK, Bykov YS, Picco A, Kukulski W, Kosinski J, Hagen WJ, Ravichandran AC, Wilmanns M, Kaksonen M, Briggs JA, Sachse C. (2016)
Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle.
EMBO Rep. 17(7):1044-1060. doi: 10.15252/embr.201541960