Location & dates EMBL Heidelberg, Germany 20 - 23 Aug 2014
Deadlines Registration closed Abstract submission closed

Programme

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Day 1 - Wednesday 20 August 2014
Time
11:00-13:00 Arrival / Registration & Welcome snacks 
13:00-13:10 Opening remarks  
Session 1: Innovations on therapeutic discovery
13:10-16:10
Chair: John Overington
13:10-13:45 High-throughput ex-vivo drug testing of patient-derived cells to facilitate individualized treatments in leukemia
Olli Kallioniemi, FIMM
13:45-14:20 Drugging cancer networks: an in-silico chemical biology view
Bissan Al-Lazikani, The Institute of Cancer Research 
14:20-14:35 Short talk: Malte Gersch  
14:35-15:05 Coffee break  
15:05-15:40 Using a chemical systems biology approach to understand and target individual cancers
Krister Wennerberg, FIMM
15:40-15:55 Short talk: Rhys Taylor  
15:55-16:10 Short talk: Herwig Schüler
16:10-18:10 Poster Session 1 with snacks 
18:10-19:00 Get together  
Keynote Session
19:00-20:00
Chair: Edward Lemke
19:00-20:00 Fluorescent Sensing and Imaging of Oxygen:  From Fiber Optics to Nanosensors for Intracellular Studies
Otto Wolfbeis, University of Regensburg
20:00 Free evening  

Day 2 - Thursday 21 August 2014
Time
Session 2: Computational methods
09:00-10:25
Chair: Bissan Al-Lazikani
09:00-09:35 Blending chemistry and biology to understand drug effects
Patrick Aloy, IRB Barcelona
09:35-10:10 Historical Perspective on Drug Design and Discovery
Yvonne Martin, Martin Consulting
10:10-10:25 Short talk: Zhengjian Zhang
10:25-10:55 Coffee break
Session 3: Cell signalling
10:55-15:40
Chair: Maja Köhn
10:55-11:30 A chemical approach to understanding cell division
Ulrike Eggert, King's College London
11:30-12:05 Synthesis of Tool Compounds for the Investigation of Lipid Metabolism and Biosynthetic Pathways
Rolf Breinbauer, Graz University of Technology
12:05-12:20 Short talk: Eileen Kennedy
12:20-13:45 Lunch
13:45-14:20 Small molecule probes and therapeutic potential of targeting protein tyrosine phosphatases
Zhong-Yin Zhang, Indiana University School of Medicine
14:20-14:55

Recent Advances in Catalomics
Shaoqin Yao, National University of Singapore

14:55-15:10 Short talk: Horiya Satoru
15:10-15:25 Short talk: Suihan Feng
15:25-15:40 Short talk: John James
15:40-16:30 Meet the speakers session & coffee break
16:30-18:30 Poster Session 2 with snacks 
Keynote Session
18:30-19:30
Chair: John Overington
18:30-19:30 Drug discovery and chemical biology: An opinionated medicinal chemistry discussion on three subtopics
Chris Lipinski, Melior Discovery
19:30-21:00 Canteen Dinner
21:00 Free evening  

Day 3 - Friday 22 August 2014
Time
Session 4: Protein engineering
09:00-12:20
Chair: Christian Hackenberger
09:00-09:35 Proximity-enabled Bioreactivity
Lei Wang, The Salk Institute for Biological Studies 
09:35-10:10 Post-translation modifications in neurodegenerative diseases; from mechanisms to biomarkers and therapeutic strategies
Hilal A. Lashuel, Swiss Federal Institute of Technology Lausanne (EPFL) 
10:10-10:25 Short talk: Liz Leunissen  
10:25-10:55 Coffee break  
10:55-11:30 Chemistry and Biology with the Ubiquitin Signal
Ashraf Brik, Ben-Gurion University 
11:30-12:05 Expanding the Synthetic Capabilities of Yeast
Virginia Cornish, Columbia University
12:05-12:20 Short talk: Gianluca Veggiani  
12:20-13:45 Lunch  
Session 5: Protein chemistry & Synthetic methods
kindly sponsored by Sanofi Aventis
13:45-15:40
Chair: Andres Jäschke
13:45-14:20 Activity-based Glycosidase profiling
Herman Overkleeft, Leiden University 
14:20-14:55 Illuminating host-pathogen interactions with photocrosslinking sugars
Jennifer Kohler, UT Southwestern Medical Center 
14:55-15:10 Short talk: Tom Grossmann  
15:10-15:25 Short talk: Elisabeth Storck Saha  
15:25-15:40 Short talk: Ivana Nikic  
15:40-16:30 Meet the Speakers Session & Coffee Break 
16:30-18:30 Poster Session 3 with snacks 
18:30-19:00 Pre-dinner drinks 
19:00-00:00 Gala Dinner & Party 

Day 4 - Saturday 23 August 2014
Time
Session 6: Controlling and engineering with light
09:00-11:45
Chair: Carsten Schultz
09:00-09:35 Tools for spying and controlling GTPase signaling networks in vivo
Klaus Hahn, University of North Carolina at Chapel Hill 
09:35-10:10 Spatiotemporal Regulation of Protein Kinases in Living Cells
Jin Zhang, Johns Hopkins University 
10:10-10:25 Short talk: Arnaud Gautier  
10:25-10:55 Coffee break  
10:55-11:30 Wavelength Tunable Photorelease of Drugs
David Lawrence, UNC Lineberger Comprehensive Cancer Center
11:30-11:45 Short talk: Laura Nevola
11:45-12:15 Coffee break
Keynote Session
12:15-13:45
Chair: Carsten Schultz
 
12:15-13:15 Protein Glycosylation: Pathways and Potential Virulence Targets
Barbara Imperiali, Massachusetts Institute of Technology 
13:15-13:25 Best Talk Award / Poster Prize and closing remarks 
13:25-13:45 Packed lunch and busses leave