Location & dates EMBL Heidelberg, Germany 8 - 11 Nov 2014
Deadlines Registration closed Abstract submission closed

Final Programme

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Day 1 - Saturday 8 November
TimeTopic
13:00-15:00 Arrival and Registration
15:00-15:05 Welcome Address

Session 1
15:05 - 18:50
Chair: Eileen Furlong

15:05-15:35

Evolutionary tradeoffs and the geometry of gene expression space
Uri Alon, Weizmann Institute of Science, Israel

15:35-16:05

Noncanonical mechanisms in the evolution of transcription factors’ DNA binding specificities
Martha Bulyk, Brigham & Women's Hospital and Harvard Medical School, United States of America

16:05-16:20

Modeling cell cycle variation in Single-Cell RNA-seq data reveals novel substructure between cells
Oliver Stegle, EMBL-EBI, United Kingdom

16:20-16:50 Exaptation and the space of possible metabolisms
Andreas Wagner, University of Zurich, Switzerland
16:50-17:20 Coffee Break
17:20-17:50 From cell populations to single molecule analysis of chromosome folding
Peter Fraser, Babraham Institute, United Kingdom
17:50-18:05 DNA methylation: genomic and epigenomic determinants of pattern generation
Tuncay Baubec, Friedrich Miescher Institute, Switzerland
18:05-18:20 The BLMP-1/LIN-42 regulatory circuit couples oscillatory transcription to temporal cell fate determination
Christopher Hammell, Cold Spring Harbor Laboratory, United States of America
18:20-18:50 Why are individuals different?
Ben Lehner, CRG, Spain
19:00-21:00 Dinner
21:00-23:00 Drinks in the ATC Roof Top Lounge
Day 2 - Sunday 9 November
TimeTopic

Session 2 kindly sponsored by Nature Reviews Genetics
09:00-12:45
Chair: Howard Chang

09:00-09:30 Enhancers/eRNAs in regulation of gene transcriptional programmes
Michael Rosenfeld, University of California, San Diego, United States of America
09:30-10:00 Sensing amino acid deficiencies in cancer
Reuven Agami, Netherlands Cancer Institute, The Netherlands
10:00-10:15 Nucleosome organisation in Drosophila
Fulvia Ferrazzi, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
10:15-10:45 RNA-binding proteins, metabolism and a new function for the genome?
Matthias W. Hentze, EMBL Heidelberg, Germany
10:45-11:15 Coffee Break
11:15-11:45 Cellular mechanisms of genome transcription
Patrick Cramer, MPI for Biophysical Chemistry, Germany
11:45-12:00 Negative feedback buffers effects of regulatory mutations
Julien Gagneur, Gene Center, LMU, Germany
12:00-12:15 The logic of the regulatory mechanism underlying growth-rate control in Escherichia coli
Evert Bosdriesz, Netherlands Cancer Institute, The Netherlands
12:15-12:45 Dissecting the genetic and epigenetic control of X-chromosome inactivation
Edith Heard, Institut Curie, France
12:45-14:00 Lunch
14:00-16:30 Poster Session I: odd numbers

Session 3
16:30 - 19:30
Chair: Ben Lehner

16:30-17:00 Individual variation in gene expression during embryonic development: new mechanisms of compensation
Eileen Furlong, EMBL Heidelberg, Germany
17:00-17:15 Relocalisation of the proteome defines a new class of functional genomic interactions
Peter Thorpe, MRC National Institute for Medical Research, United Kingdom
17:15-17:45 Recursive splicing regulates use of poison exons within long neuronal genes
Jernej Ule, UCL Institute of Neurology, United Kingdom
17:45-18:15 Coffee Break
18:15-18:45 Regulatory RNAs
Nikolaus Rajewsky, Max Delbrück Center for Molecular Medicine, Germany
18:45-19:00 Pathway crosstalk quantification reveals synergistic drug combinations against breast cancer
Samira Jaeger, IRB Barcelona, Spain
19:00-19:30 Whole cell model of a small bacteria, what have we learned
Luis Serrano, CRG, Spain
19:30-21:00 Dinner
21:00-23:00 Drinks in the ATC Roof Top Lounge
Day 3 - Monday 10 November
TimeTopic
Session 4
09:00 - 12:45
Chair: Joanna Wysocka
09:00-09:30 Deciphering regulatory circuitry by genome-wide analyses
Frank Holstege, University Medical Center Utrecht, The Netherlands
09:30-10:00 Epigenomic signals identify novel genes and pathways associated with cardiac traits
Laurie Boyer, Massachusetts Institute of Technology, United States of America
10:00-10:15 Transcript abundance in human cells approaches perfect controllability
Nico Battich, University of Zurich, Switzerland
10:15-10:45 Genetics and Genomics of piRNA biogenesis
Julius Brennecke, IMBA, Austria
10:45-11:15 Coffee Break
11:15-11:45 Genetic basis of chromatin states and gene expression in humans involves local and distal chromosomal interactions
Judith Zaugg, EMBL Heidelberg, Germany
11:45-12:00 Inferring Directional Genetic Interactions from multi-parametric combinatorial screens
Bernd Fischer, DKFZ, Germany
12:00-12:15 Genome-wide activity maps of signal-dependent enhancers
Daria Shlyueva, Research Institute of Molecular Pathology (IMP), Austria
12:15-12:45 Imaging RNA and RNA biology using RNA mimics of green fluorescent protein
Samie Jaffrey, Weill Cornell Medical College, United States of America
12:45-14:00 Lunch
14:00-16:30 Poster Session II: even numbers
Session 5
16:30-19:30
Chair: Eran Segal
16:30-17:00 Genome-wide analysis of protein-DNA interactions
Jussi Taipale, Karolinska Institutet, Sweden
17:00-17:15 Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress
Vanessa Vermeirssen, VIB - Ghent University, Belgium
17:15-17:45 Intrinsic retroviral reactivation during human development
Joanna Wysocka, Stanford University, United States of America
17:45-18:15 Coffee Break
18:15-18:45 Genome Regulation by Long Noncoding RNAs
Howard Chang, Stanford University, United States of America
18:45-19:00 Genomics of drug sensitivity in primary lymphoid malignancies
Wolfgang Huber, EMBL Heidelberg, Germany
19:00-19:30 Linking epigenetics and signalling in the early mammalian embryo
Amanda Fisher, MRC Clinical Sciences Centre, United Kingdom
19:30-01:00 Conference dinner and Party
Day 4 - Tuesday 11 November
TimeTopic
Session 6
09:00-12:45
Chair: Frank Holstege
09:00-09:30 Direct determination of DNA-protein interactions by proteomics
Matthias Mann, MPI of Biochemistry, Germany
09:30-09:45 The genomic landscape of compensatory evolution
Gabor Boross, Biological Research Centre, Hungary
09:45-10:00 Widespread intron retention in mammals functionally tunes transcriptome
Ulrich Braunschweig, University of Toronto, Canada
10:00-10:15 Specificity, propagation and memory of chromatin states
Karsten Rippe, German Cancer Research Center (DKFZ), Germany
10:15-10:45 Genetic and epigenetic determinants of hematopoiesis in humans
Nicole Soranzo, Wellcome Trust Sanger Institute, United Kingdom
10:45-11:15 Coffee Break
11:15-11:45 Unraveling principles of gene regulation using thousands of designed regulatory sequences
Eran Segal, Weizmann Institute, Israel
11:45-12:00 Mapping chromatin dynamics after DNA replication
Marta Radman-Livaja, CNRS, France
12:00-12:15 Prioritising the investigation of human metabolic functions from their metabolic context
Ottar Rolfsson, Center for Systems Biology, University of Iceland, Iceland
12:15-12:45 Single-cell dynamics of genome - nuclear lamina interactions
Bas van Steensel, Netherlands Cancer Institute, The Netherlands
12:45-12:50 Closing remarks
12:50 Packed Lunch
13:15 Bus Downtown and Frankfurt Airport