Location & dates EMBL Heidelberg, Germany 1 - 4 Nov 2015
Deadlines Registration closed Abstract submission closed

Conference Programme

Day 1 - Sunday 1 November 2015
TimeSpeaker
12:00-13:15 Registration with light refreshments
13:15-13:30 Opening remarks

Session 1: Cancer Genetics
13:30-16:45
Chairs: Jan Korbel & Peter Campbell

13:30-14:00 Genomic spectra of biliary tract cancer
Tatsuhiro Shibata, National Cancer Center Research Institute
14:00-14:30 Neurooncology: next-generation diagnostics entering the clinical stage
Stefan Pfister, German Cancer Research Center
14:30-15:00

Genomic characterisation and risk stratification of acute myeloid leukaemia
Moritz Gerstung, EMBL-EBI

15:00-15:30 Coffee Break
15:30-15:45

Selected talk: Anelia Horvath, George Washington University

15:45-16:00 Selected talk: Ludmil Alexandrov, Los Alamos National Laboratory
16:00-16:30

Jan Korbel, EMBL Heidelberg

16:30-16:45 Selected talk: Jakob Pedersen, Aarhus University Hospital
16:45-17:30 Coffee Break & Meet the Speakers
17:30-18:30 Keynote lecture: Signatures of mutational processes
Michael Stratton, Wellcome Trust Sanger Institute
18:30-20:00 Dinner
20:00-22:00 Welcome reception and dessert in the ATC Rooftop Lounge
Day 2 - Monday 2 November 2015
TimeSpeaker

Session 2: Computational & Systems Biology of Cancer
09:00-12:00
Chair: Stefan Pfister

09:00-09:30 The heterogeneous landscape of mutations in Breast cancer and their association with genomic features
Ewan Birney, EMBL-EBI
09:30-09:45 Selected talk: Jimmy van den Eynden, University of Gothenburg
09:45-10:00 Selected talk: Michael Menden, EMBL-EBI
10:00-10:30 Cancer drivers and their therapeutic opportunities
Núria Lopez-Bigas, University Pompeu Fabra - UPF
10:30-11:00 Coffee Break
11:00-11:30 Cancer Predisposition in the Era of Next Generation Sequencing
Andrew Biankin, Wolfson Wohl Cancer Research Centre, University of Glasgow
11:30-11:45 Selected talk: Atanas Kamburov, Massachusetts General Hospital / Broad Institute
11:45-12:00 Selected talk: Bernd Fischer, German Cancer Research Center
12:00-13:15 Lunch
13:15-15:15 Poster Session I (odd numbers)
Session 3: Insights into Cancer Genome Biology
15:15-18:45
Chairs: Andrew Biankin & Nuria Lopez-Bigas
15:15-15:45

Big Data and the International Cancer Genome Consortium
Lincoln Stein, Ontario Institute for Cancer Research

15:45-16:00 Selected talk: Radhakrishnan Sabarinathan, Universitat Pompeu Fabra
16:00-16:30 Computational Characterization of Mutational Heterogeneity in Cancer
Ben Raphael, Brown University
16:30-17:15 Coffee Break & Meet the Speakers
17:15-17:30 Selected talk: Mei Wang, Karolinska Institutet
17:30-17:45 Selected talk: Jayendra Shinde, INSERM
17:45-18:15 Integrated analysis of pancreatic cancer
Sean Grimmond, Wolfson Wohl Cancer Research Centre, University of Glasgow
18:15-18:30 Selected talk: Ingegerd Elvers, Broad Institute of MIT and Harvard; Uppsala University
18:30-18:45 Selected talk: David Goode, Peter MacCallum Cancer Centre
18:45-20:30 Dinner
20:30-22:00 After Dinner drinks and dessert in the ATC Rooftop Lounge
Day 3 - Tuesday 3 November 2015
TimeSpeaker

Session 4: Cancer Functional Genomics  & Epigenomics
09:00-12:00
Chair: Tatsuhiro Shibata

09:00-09:30 Precision medicine: cancer genomics and beyond
Carlo Toniatti, MD Anderson Cancer Center
09:30-09:45 Selected talk: Cagatay Gunes, Fritz-Lippman-Institute
09:45-10:00 Selected talk: Julian de Ruiter, Netherlands Cancer Institute
10:00-10:30 Translating Cancer Genomics into Novel Drug Targets
John Brognard, Cancer Research UK Manchester Institute
10:30-11:15 Coffee Break
11:15-11:45 Genome-epigenome interplay in medulloblastoma
Paul Northcott, St. Jude Children's Research Hospital
11:45-12:00 Selected talk: Meganathan Poorlin Ramakodi, Fox Chase Cancer Center-Temple Health
12:00-13:15 Lunch
13:15-15:15 Poster Session II (even numbers)
Session 5: Genome Medicine & Big Data
15:15-19:00
Chairs: Ben Raphael & Lynda Chin
15:15-15:45

Interrogating the architecture of cancer genomes
Peter Campbell, Wellcome Trust Sanger Institute

15:45-16:00 Selected talk: Francesco Iorio, EMBL-EBI
16:00-16:45 Coffee Break & Meet the Speakers
16:45-17:15

Understanding the genomic steps from Barrett’s oesophagus to oesophageal cancer and applications to earlier diagnosis
Rebecca Fitzgerald, University of Cambridge

17:15-17:45 Transforming cancer research and care
Lynda Chin, Institute for Health Transformation, University of Texas System
17:45-18:00 Selected talk: Alexander Urban, University Medical Center Göttingen
18:00-19:00 Keynote Lecture: Watson and Genomics: How cognitive computing will transform medicine
Mike Rhodin, IBM Watson Group
19:00-19:15 Closing remarks and poster prize giving
19:15-00:00 Banquet Dinner & Party

Day 4 - Wednesday 4 November 2015
TimeSpeaker
Session 6: Workshop for young scientists:
Analytics of Cancer Genomes with focus on Pan-Cancer Analysis
09:00-12:15
Chairs: Jan Korbel & Postdocs

09:00-09:05 Welcome remarks
09:05-09:15 Modeling Higher Moments in Cancer Genomics: A Different Way to Understand Gene Regulation
Jessica Mar, Albert Einstein College of Medicine
09:15-09:25 Non-coding driver detection using site-specific regression of the expected mutation rate
Malene Rasmussen, Aarhus University Hospital
09:25-09:35 OncodriveFML: A general framework to identify coding and non-coding regions with cancer driver mutations
Loris Mularoni, Universitat Pompeu Fabra
09:35-09:55 Discussion (workshop session 1)
09:55-10:05 Estimating the impact of cis-regulatory variation in cancer genomes using enhancer prediction models and matched genome-epigenome-transcriptome data
Zeynep Kalender Atak, KU Leuven
10:05-10:15 Pan-cancer transcriptomic analysis associates long non-coding RNAs with key driver mutational events
Arghavan Ashouri, University of Gothenburg
10:15-10:30 Discussion (workshop session 2)
10:30-11:00 Coffee Break
11:00-11:10 Allele-specific copy number estimation from sequencing - ACEseq
Kortine Kleinheinz, German Cancer Research Center
11:10-11:20

Predicting the mechanistic impact of mutations and modifications on molecular interactions
Matthew Betts, University of Heidelberg

11:20-11:30

Exploring the impact of natural and aberrant structure variations in oncoprotein-mediated signaling networks through structural bioinformatics
Francesco Raimondi, University of Heidelberg

11:30-12:15 Discussion (workshop session 3 & concluding discussion)
12:15-12:45 Packed lunch
12:45 Busses leave to Frankfurt Int. Airport and downtown Heidelberg