Location & dates EMBL Heidelberg, Germany 16 - 19 Nov 2015
Deadlines Registration closed Abstract submission closed
organiser_stanford

Programme

Day 1 - Monday 16 November 2015
TimeSpeaker
17:00-18:55 Session 1
Chair:
Polly Fordyce - Stanford University, USA
17:00-17:10 Opening remaks
17:10-17:55

Keynote Lecture
Systems Medicine and Proactive P4 Medicine: Transforming Healthcare through Wellness—A Personal View

Lee Hood - Institute for Systems Biology, USA

17:55-18:25

The UK 100,000 genomes project: towards personalised health in the NHS
Tim Hubbard - King's College London, UK

18:25-18:55

Microfluidic approaches in personalized medicine
Christoph Merten - EMBL Heidelberg, Germany

18:55-19:55

Dinner

19:55-22:30 Welcome reception with live music: "Blue Note Jazz Band"
Drinks in the ATC Roof Top Lounge
Day 2 - Tuesday 17 November 2015
TimeSpeaker
09:00-12:00 Session 2
Chair:
Lee Hood - Institute for Systems Biology, USA
09:00-09:30 Using systems genetics to dissect a rare disease and levitate cells
Lars Steinmetz - EMBL Heidelberg, Germany & Stanford University, USA
09:30-10:00

Explaining variable drug response of primary tumours through multi-omics
Wolfgang Huber EMBL Heidelberg, Germany

10:00-10:30

Genetic basis of variation in gene regulatory elements and its link to complex diseases
Judith Zaugg EMBL Heidelberg, Germany

10:30-11:00

Coffee Break

11:00-11:30

Primal fear: neural circuits controlling defensive behavior
Cornelius Gross - EMBL Monterotondo, Italy

11:30-11:45

Monitoring of circulating tumour cells in patients with breast cancer
Anna Jakabová - Third Faculty of Medicine, Charles University in Prague, Czech Republic

11:45-12:00

Targeted mass spectrometric analysis of the cellular response to the perturbations of the LXR and SREBP pathway
Peter Blattmann - ETH Zurich, Switzerland

12:00-13:30 Lunch & "Meet the Speakers Session"
13:30-17:30 Session 3
Chair:
Judith Zaugg EMBL Heidelberg, Germany
13:30-14:00

Health, disease and the personalised metagenome
Ami Bhatt- Stanford University, USA

14:00-14:30

Leveraging spectral encoding for high-dimensional biological multiplexing
Polly Fordyce - Stanford University, USA

14:30-15:00

Coffee Break

15:00-15:30

Genomics approaches to the complex genetics of brain function
Alex Urban - Stanford University, USA

15:30-16:00

Poster Flash Talks
Even Numbers

16:00-17:30

Poster Session I
Even Numbers

Helix A

17:30-19:00 Session 4
Chair: 
Anshul Kundaje - Stanford University, USA
17:30-18:00

Learning about the Genetic Architecture of Complex Traits Across Populations
Hua Tang - Stanford University, USA

18:00-18:15

A map of directional genetic interactions in a metazoan cell
Bernd Fischer - DKFZ, Germany

18:15-18:30

Gene-environment interactions between the Mediterranean diet and relevant candidate genes on cardiovascular risk factors and disease in the PREDIMED randomized controlled trial
Dolores Corella - CIBER / University of Valencia, Spain

18:30-19:00 Vascular wall disease pathways from coronary disease genome wide association loci
Thomas Quertermous - Stanford University, USA
19:00-20:30 Dinner
20:30-22:00 Drinks in the Roof Top Lounge
Day 3 - Wednesday 18 November 2015
TimeSpeaker
09:00-12:00 Session 5
Chair: Ewan Birney - EMBL-EBI, UK
09:00-09:30 Modeling cancer evolution from genomic data
Niko Beerenwinkel - ETH Zurich, D-BSSE, Switzerland
09:30-10:00

An integrated systems pharmacology approach to drug efficacy and safety
John Overington - Stratified Medical, UK

10:00-10:30

Translating lymphoma geneticts into clinical care
Thorsten Zenz - Nationales Centrum für Tumorerkrankungen Heidelberg, Germany

10:30-11:00

Coffee Break

11:00-11:30

Dissecting the sources of variation in induced pluripotent stems cells
Oliver Stegle - EMBL-EBI, UK

11:30-11:45

Comparative sequencing of cancer biopsy pairs reveals intratumor heterogeneity and patterns of co-occurring mutated genes
Ariane Hofmann - ETH Zurich, Switzerland

11:45-12:00 Large-scale prediction of disease risk using 18 years of registry data from 6.8 million Danes
Anders Jensen - University of Copenhagen, Denmark
12:00-13:30 Lunch & "Meet the Speakers Session"
13:30-18:00 Session 6
Chair: Ami Bhatt- Stanford School of Medicine, USA
13:30-14:00

Big Data in translational medical research
Ewan Birney- EMBL-EBI, UK

14:00-14:30

Integrative models for characterizing the effects of regulatory variation
Alexis Battle - Johns Hopkins University, USA

14:30-15:00

Coffee Break

15:00-15:30

Rare regulatory variation in individuals, families and populations
Stephen Montgomery - Stanford University, USA

15:30-16:00

Poster Flash Talks
Odd Numbers

16:00-17:30

Poster Session II
Odd Numbers
Helix A

17:30-19:30

Session 7
Chair: Mike Snyder, Stanford University, USA

17:30-18:00 Keynote Lecture
Title to be announced
Hank Greely - Stanford School of Medicine, USA
18:00-18:30 The dawn of a new research model: the case for parent - clinician - researcher collaboration
Matt Wilsey - Grace Wilsey Foundation, USA
18:30-19:30

Panel Discussion
Chair: Mike Snyder, Stanford University, USA
Ami Bhatt- Stanford University, USA
Ewan Birney - EMBL-EBI, UK
Christof von Kalle Nationales Centrum für Tumorerkrankungen Heidelberg, Germany
Hank Greely - Stanford School of Medicine, USA
Matt WilseyGrace Wilsey Foundation, USA

19:30-midnight Gala Dinner & Conference Party
Day 4 - Thursday 19 November 2015
TimeSpeaker
10:00-13:00 Session 8
Chair:
Jan Korbel EMBL Heidelberg, Germany
10:00-10:30

Dynamical multiscale modelling to understand multigenic congenital abnormalities: limb defects
James Sharpe - Centre for Genomic Regulation, Spain

10:30-11:00

Unlocking the potential of omics and clinical data for Personalized Healthcare
Werner Eberhardt - SAP (Health), Germany

11:00-11:30

The Pan-Cancer Analysis of Whole Genomes Initiative: a big data approach to cancer genomics
Jan Korbel EMBL Heidelberg, Germany

11:30-12:00

Coffee Break

12:00-12:30

Functional variation in the human genome: lessons from the transcriptome
Tuuli Lappalainen - Columbia University, USA

12:30-12:45

Individual heritable differences result in unique B and T cell receptor repertoires of naïve and antigen-experienced cells
Florian Rubelt - Stanford University, USA

12:45-13:00

Deep Sequencing Analysis of Clonal Evolution in Acute Myeloid Leukemia from Diagnosis to Relapse
Poojitha Ojamies - FIMM-University of Helsinki, Finland

13:00-14:30 Lunch & "Meet the Speakers Session"
14:30-16:00 Session 9
Chair:
Alexis Battle - Johns Hopkins University, USA
14:30-15:00

De-novo inference of enhancer-gene networks in diverse cellular contexts reveals the long-range regulatory impact of disease-associated variants
Anshul Kundaje - Stanford University, USA

15:00-15:15

Dynamic secretion profiling of single cells from rare cell populations
Alicia Kaestli - ETH Zürich, Switzerland

15:15-15:30

Personalized genome scale metabolic modelling of subjects with varying degree of Hepatic steatosis
Adil Mardinoglu - Chalmers University of Technology, Sweden

15:30-16:00

Precision Oncology – Efforts at NCT
Christof von Kalle Nationales Centrum für Tumorerkrankungen Heidelberg, Germany

16:00-16:30

Coffee Break

16:30-19:20

Session 10
Kickoff of the Life Science Alliance between Stanford University and EMBL
Chair: 
Lars Steinmetz, Stanford University and EMBL Heidelberg, Germany 

16:30-16:40

Introduction to the Alliance with a Focus on Genomics
Lars Steinmetz, Stanford University and EMBL Heidelberg, Germany  

16:40-16:50

Joint Activities from a Stanford Perspective
Mike Snyder, Stanford University, USA    

16:50-17:10 EMBL's Multidisciplinary Approach to Biology and Health
Iain Mattaj - Director General, EMBL Heidelberg, Germany
17:10-17:30 Precision Health at Stanford Medicine
Lloyd Minor - Dean, Stanford University School of Medicine, USA
17:30-18:00 Coffee Break
18:00-18:30 Personalized Medicine: Using omics profiling and big data to understand and manage health and disease
Mike Snyder - Stanford University, USA
18:30-19:00 Microbiome analysis of the human gut in a planetary context
Peer Bork - EMBL Heidelberg, Germany
19:00-19:10

Frontiers in Structural Biology: Catching new Opportunities
Matthias Wilmanns - EMBL Hamburg, Germany

19:10-19:20

Pushing the Limits of Biological Imaging
Jan Ellenberg - EMBL Heidelberg, Germany

19:20-19:30 Closing remarks
19:30 Dinner