Adrian V.S. Hill
Adrian V.S. Hill is Professor of Human Genetics and Director of the Jenner Institute at Oxford. He leads research programmes in both the genetics of susceptibility to tropical infectious diseases and in vaccine development. He trained in medicine at Trinity College, Dublin and Oxford and was awarded a DPhil for population genetic studies of the thalassaemias in 1986 before further clinical training. His research group at the Wellcome Trust Centre for Human Genetics in Oxford have identified variants in genes that affect resistance to malaria, tuberculosis, sepsis and other infectious diseases. These findings have informed vaccine development helping his group to design and develop leading new vaccines for malaria. These are currently in clinical trials in the UK and at several collaborating sites in Africa.
In 2005 he was appointed Director of the new Jenner Institute at Oxford, an initiative aimed at accelerating public sector vaccine development for a range of infectious diseases, and partnered with the Pirbright Institute on veterinary vaccine development. The Jenner Institute is now the largest academic vaccine centre in Europe. In 2014 – 2015 four of the five new Ebola vaccines that reached field trials in Africa were tested first in humans at Oxford. He has published about 500 research papers, many in leading journals with over 50,000 citations. He is a Fellow of the UK Academy of Medical Sciences and the Royal College of Physicians, and both a Wellcome Trust and UK NIHR Senior Investigator.