Location & dates EMBL Heidelberg, Germany 6 - 8 Jun 2016
Deadlines Registration closed Abstract submission closed

Final Programme

 

Day 1 - Monday 6 June 2016
TimeSpeaker/Title
11:00-12.45 Registration and Lunch
12:45-13:00 Welcome to EMBL and Opening remarks
Iain Mattaj, EMBL, Germany
13:00-13:15

Introduction to the EMBL Partnership Programme
Silke Schumacher, EMBL, Germany

13:15-14:15

RNA-binding proteins, metabolism and a new function for the genome?
Special Lecture: Matthias Hentze EMBL, Germany

Session 1
14:15-17:50
Chair: James Sharpe, CRG, Spain

14:15-14:40

Iron homeostasis in health and disease
Martina Muckenthaler, MMPU and University Medical Center for Children and Adolescents, Heidelberg University, Germany

14:40-14:55

Simple and complex retinal dystrophies are associated to profoundly different disease networks
Christina Kiel, CRG Barcelona

14:55-15:25 Coffee Break
15:25-15:50

Dyslipidemias - Mendelian or polygenic disorders?
Samuli Ripatti, FIMM, Finland

15:50-16:05

Combining known weapons to stop the fungal enemy
Sujan Yellagunda R, Umeå University, Sweden

16:05-16:30

Dynamical multiscale modelling to understand multigenic congenital abnormalities: limb defects
James Sharpe, CRG, Spain

16:30-16:45

Visualization of channel-activating protease (CAP) activity by peptide-based FRET probes
Verena Rickert-Zacharias, EMBL Heidelberg

16:45-17.10

Liquid Biopsy: Blood-based detection and characterization of circulating tumor cells and circulating nucleic acids
Klaus Pantel, UKE, Germany

17:10-18:10

Speed networking

18:20-20:00

Poster session 1 (Wine and cheese available at the ATC Foyer)

Day 2 - Tuesday 7 June 2016
TimeSpeaker
Session 2
09:00-13:35
Chair: Poul Nissen DANDRITE
09:00-09:25

Under the skin: pain mechanisms in the peripheral nervous system
Paul Heppenstall, EMBL, Italy

09:25-09:40

Genetic predisposition to somatic mutational processes across 2800 cancer patients
Sebastian Waszak, EMBL

09:40-09:55

Genetic basis of variation in gene regulatory elements and its link to complex diseases
Judith Zaugg, EMBL, Germany

09:55-10:20

Modeling Human Neural Development and Disease with Stem Cells
Mark Denham, DANDRITE, Denmark

10:20-10:50

Coffee Break

10:50-11:15

Linking retinal computation to disease
Keisuke Yonehara, DANDRITE, Denmark

11:15-11:30

Trpm2 is a hypothalamic heat sensor that regulates fever and thermal homeostasis
Gretel Kamm, Heidelberg University, Germany

11:40-11:45 Tuning of the Na,K-ATPase by the beta subunit
Florian Hilbers, DANDRITE, Denmark
11:55-12:10

Neuroregeneration via cell fate reprogramming
Maria Pia Cosma, CRG, Spain

12:10-13:35

Lunch and Poster Session 2

Session 3
13:35-16:40
Chair: Sun Nyunt Wai Umeå University, Sweden

13:35-14:00

Structural insights into RNA synthesis by the influenza virus transcription-replication machine
Stephen Cusack, EMBL, Germany

14:00-14:25

Exploring the structure, assembly and inhibition of HIV-1 by cryo-electron microscopy
John Briggs, EMBL and MMPU, Germany

14:25-14:40

Nanopore based identification of carbapenemase-resistance carrying hospital bacteria
Mattia Bosio, CRG, Spain

14:40-15:05 Friend of foe? - Dissecting the type-3 secretion system in action by cryo electron microscopy
Thomas Marlovits, UKE, Germany
15:05-15:30 Coffee Break
15:30-15:55

New Concepts on the Role of DNA Damage and the Ubiquitin System in Innate Immune Regulation
Nelson Gekara, MIMS, Sweden

15:55-16:10 Increased Plasmid Copy-number is Essential for Yersinia T3SS Function and Virulence
He Wang, Umea University, Sweden
16:10-16:35

Tick-borne encephalitis virus and the antiviral interferon system
Anna Överby, MIMS , Sweden

16:35-17.00

The Magnesium importer A in E. coli control a magnesium sensitive feedback system
Jens Preben Morth, NCMM, Norway

17:00-17:25

Coffee Break

17:25-17:50

Using human genetics to help make new medicines
Jeffrey Barrett, Open targets, United Kingdom

17:50-18:35

Panel Discussion `Translating research from bench to bedside`

Moderator: Iain Mattaj, EMBL, Germany

Pannelists:
Jeffrey Barrett, Open targets, United Kingdom
Emmy Verschuren, FIMM, Finland, Nordic EMBL Partnership for Molecular Medicine
Emmanuelle Charpentier, MIMS, Sweden, Nordic EMBL Partnership for Molecular Medicine, and Max Planck Institute for Infection Biology, Germany
Stefan Fröhling, NCT, Germany
Andreas Kulozik University Medical Center for Children and Adolescents, Heidelberg University, Germany

19:30

Dinner Downtown
Palais Prinz Carl Restaurant

Busses leave at 18:45

Day 3 - Wednesday 8 June 2016
09:00-10:00 Special Lecture
Emmanuelle Charpentier
MIMS (Sweden), Nordic EMBL Partnership for Molecular Medicine, and Max Planck Institute for Infection Biology, Germany
TimeSpeaker

Session 4
10:00-13:25
Chair: Jeffrey Barrett, Open targets, United Kingdom

10.00-10:25 Targeting cancers using individualized systems medicine
Krister Wennerberg FIMM, Finland, Nordic EMBL Partnership for Molecular Medicine
10:25-10.40

Phenotypic image-based screening in the analysis of patient-derived cancer cells ex-vivo
Vilja Pietiäinen, Institute for Molecular Medicine Finland

10:40-11:05

Molecular targets of MYC-driven lymphoma
Jennifer Hüllein, National Center for Tumor Diseases (NCT) / German Cancer Research Center (DKFZ), Heidelberg

11:05-11:20

Genomics of drug sensitivity of leukemia and lymphoma
Thorsten Zenz, NCT, Germany

11:20-11.45

Coffee break

11.45-12:10

Coping with stress and exploiting it
Ian G. Mills, NCMM, Norway

12:10-12:25 Precision medicine strategies for high-risk multiple myeloma to address variability in drug response and predicting treatment outcome
Muntasir Majumder, Institute of Molecular Medicine, Finland
12:25-12:400

A phosphoflow based approach for the assistance of clinical decisions  in individualized cancer therapy
Sigrid S Skånland, Norwegian centre for molecular medicine (NCMM), University of Oslo, Norway

12:40 -13:05

Tumor classification based on cell of origin fingerprints using genome-wide DNA methylation analysis
Stefan Pfister, NCT (Germany)

13:05-13:20

Closing remarks and poster prize

13:45

Packed lunch and bus to downtown and Frankfurt Airport.