Location & dates EMBL Heidelberg, Germany 29 - 31 May 2017
Deadlines Registration closed Abstract submission closed

Conference Programme

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Day 1 - Monday 29 May 2017
09.30-11.00 Registration
11:00-11:15 Welcome and Introduction

Scientific Session 1 Vector Biology
Chairs: Gabriele Pradel - RWTH Aachen University, Germany and Anastasia Accoti - University of Perugia, Italy

11:15-11:45 Keynote lecture
What do we know about malaria vectors

Elena Levashina - MPI for Infection Biology, Germany
11:45-12:00 A high throughput genetic screen for malaria transmission phenotypes in the Plasmodium berghei – Anopheles gambiae experimental model
George Christophides - Imperial College London, United Kingdom
12:00-12:15 An old secret language between malaria parasite and its vector
S.Noushin Emami - Stockholm University, Sweden        
12:15-12:30 Malaria parasite lifecycle progression from host to vector reflected in the Plasmodium berghei epigenetic footprint
Kathrin Witmer - Imperial College London, United Kingdom
12:30-14:00 Lunch and meet the Keynote speaker
14:00-15:30 Scientific session 2 Immunobiology
Chairs: Hedda Wardemann, German Cancer Research Center (DKFZ), Germany and Gathoni Kamuyu, KEMRI-Wellcome Trust Research Programme, United Kingdom
14:00-14:30 Keynote Lecture
Recent insights into the cell biology of humoral immunity to malaria

Peter Crompton - NIAID/NIH, United States of America
14:30-14:45 Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load
Blandine M.D. Franke-Fayard - Leiden University Medical Centre, The Netherlands
14:45-15:00 Clec9a+ CD8+ Dendritic Cells are Key Players in Controlling Plasmodium chabaudi chabaudi Infection
Si Min Lai - Nanyang Technological University, Singapore
15:00-15:15 Binding properties and anti-sporozoite activity of monoclonal antibodies from protected Tanzanian volunteers
Joshua Tan - Institute for Research in Biomedicine, Switzerland
15:15-15:30 Speed Talks for Poster Session 1
15:30-16:00 Coffee Break
16:00-18:00 Poster Session 1 - Odd numbers
18:00-18:45 Lifetime Achievement Award
18:45-20:30 Dinner
20:30-23:00 Welcome Reception/After Dinner Drinks with SOULmate Band
Day 2 - Tuesday 30 May 2017
09:00-10:30 Scientific session 3 Big data and New technologies
Chairs: Mario Recker, University of Exeter, United Kingdom and Anush Chiappino-Pepe, École Polytechnique Fédérale de Lausanne (EPFL), Switzerland
09:00-09:30 Keynote Lecture
Single cell RNA sequencing resolves bifurcation of T cell fates during Plasmodium chabaudi infection

Tapio Lönnberg - University of Turku, Finland
09:30-09:45 Single-cell transcriptomics of malaria parasites
Arthur Talman - Wellcome Trust Sanger Institute, United Kingdom
09:45-10:00 Chromatin accessibility based characterization of gene regulation in Plasmodium falciparum
Richard Bartfai - Radboud University Nijmegen, The Netherlands
10:00-10:15 Draft genome of bat malaria parasite reveals host switch and adaptation
Mohamed Almarri - Wellcome Trust Sanger Institute, United Kingdom
10:15-10:30 Population transcriptomics studies of the origins of drug resistance of Plasmodium falciparum in the Greater Mekong Subregion
Zbynek Bozdech - School of Biological Sciences, Nanyang Technological University Singapore               
10:30-11:00 Coffee Break
11:00-12:30 Scientific session 4 Host - Parasite Interaction
Chairs: Peter Bull - University of Cambridge, United Kingdom and Yvonne Adams - University of Copenhagen, Denmark
11:00-11:15 Malaria & PfEMP1´s ABC – easy as 1-2-3?
Thomas Lavstsen - University of Copenhagen, Denmark   
11:15-11:30 Plasmodium falciparum infected erythrocytes from cerebral malaria cases bind preferentially to brain microvascular endothelium; a study in Malawian children
Janet Storm - Liverpool School of Tropical Medicine, United Kingdom
11.30-11.45 Plasmodium falciparum Heterochromatin Protein 1 reveals expression of a clonally variant PfEMP1 member on the surface of sporozoites
Gigliola Zanghì - Institut Pasteur, France
11.45-12.00 Differential location and interactions of PfRH1 processing products during merozoite invasion
Peter Preiser - Nanyang Technological, University Singapore 
12.00-12.15 Profiling Plasmodium falciparum Sexual Commitment at the Single Cell Level
Nicolas Brancucci - University of Glasgow, United Kingdom
12.15-12.30 Dynamics of Plasmodium gametocytes in the host bone marrow
Mariana De Niz - Wellcome Centre for Molecular Parasitology, United Kingdom
12.30-14:00 Lunch and meet the Keynote speaker
13:00-14:00 Workshop 1: Imaging
Freddy Frischknecht - Heidelberg University, Germany
13:00-14:00 Workshop 2: Single Cell sequencing
Tapio Lönnberg - University of Turku, Finland
14:00-16:00 Scientific Session 5 Molecular and Cellular Biology
Chairs: Moritz Treeck, The Francis Crick Institute - United Kingdom and Manuela Carrasquilla - Wellcome Trust Sanger Institute/University of Cambridge, United Kingdom
14:00-14.30 Keynote Lecture
Till Voss - Swiss Tropical and Public Health Institute, Switzerland
14:30-14:45 Plasmodium falciparum Dipeptidyl Aminopeptidase 3 Is Important for Efficient Attachment of Merozoites to Erythrocytes
Christine Lehmann - The Francis Crick Institute, United Kingdom
14.45-15.00 The role of host factors in P. falciparum-mediated host erythrocyte modification
Jude Przyborski - Philipps University, Germany
15.00-15.15 Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony and is critical for transmission
Markus Ganter - Heidelberg University Medical School, Germany
15.15-15.30 Single-molecule analysis reveals that DNA replication dynamics vary across the course of schizogony in the malaria parasite Plasmodium falciparum
Catherine Merrick - Keele University, United Kingdom
15.30-15.45 Speed Talks for Poster Session 2
15:45-16:30 Coffee Break
16.30-18.30 Poster Session 2 - Even numbers
18.30-20.00 Gala Dinner
20.00-21.00 PI Band Pumphandle Blues
21.00-24.00 DJane Heidi Van De Alm, University of Popular Music and Music Business, Mannheim
Day 3 - Wednesday 31 May 2017
09:00-10:30 Scientific session 6 - Pathology and Epidemiology
Chair: Lars Hviid - University of Copenhagen, Denmark and Jo-Anne Chan - Burnet Institute, Australia

Keynote Lecture
Global Malaria Epidemiology and the Response

Philip Bejon - KEMRI Wellcome Trust Research Programme, Kenya

09:30-09:45 Magnetic resonance imaging of cerebral malaria patients reveals distinct pathogenetic processes in different parts of the brain
Samuel Wassmer - London School of Hygiene & Tropical Medicine, United Kingdom
09:45-10:00 Retinal Endothelial Dysfunction in Malawian Children with Fatal Cerebral Malaria
Valentina Barrera - University of Liverpool, United Kingdom
10:00-10:15 Development of an experimental human blood stage infection model of Plasmodium malariae
James McCarthy - QIMR Berghofer, Australia   
10:15-10:30 Correlates of protection from Controlled Human Malaria Infections (CHMI) in semi-immune Kenyan adults
Faith Osier - Heidelberg University Hospital, Germany
10:30-11:00 Coffee Break
11:00-15:30 Scientific session 7 Molecular and Cellular Biology
Chair: Katja Becker - University of Giessen, Germany and Emilie Njila - RWTH Aachen University, Germany
11.00-11.15 Dissecting the role of PfAP2-G in the regulation of gametocytogenesis
Gabrielle Josling - The Pennylvania State University, United States of America
11:15-11:30 The RNA binding ALBA3 protein acts as a positive regulator of Plasmodium erythrocytic cycle and gametocyte production
Nisha Philip - Wellcome Centre for Molecular Parasitology, University of Glasgow, United Kingdom
11.30-11.45 Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites
Lyn-Marie Birkholtz - University of Pretoria, South Africa 
11.45-12.00 CRISPR-Cas9 in P. knowlesi enables rapid, iterative and scalable targeted modification of the parasite genome
Franziska Mohring - London School of Hygiene and Tropical Medicine, United Kingdom
12.00-12.15 Re-evaluation of calcium during merozoite invasion
Viola Introini - University of Cambridge, United Kingdom
12.15-12.30 Understanding artemisinin action in Plasmodium falciparum
Natalie Spillman - The University of Melbourne, Australia
12.30-14:00 Lunch and meet the Keynote speaker
13:00-14:00 Workshop 3: CRISP/Cas9
Marcus Lee - Wellcome Trust Sanger Institute, United Kingdom and Jose Juan Lopez Rubio - University of Montpellier, France
13:00-14:00 Workshop 4: Analysis of big data
Thomas D Otto - Wellcome Trust Sanger Institute, United Kingdom
14:00 -14:15

MMV sponsored talk

A perforin like protein facilitates entry of Plasmodium falciparum merozoites by forming calcium permissive pores in the host erythrocyte
Shailja Singh - Jawaharlal Nehru University, India 

14:15-15:30 Panel Discussion: Now what? -Careers in Academia, Industry and Education
15.30-15.45 Awards for best Posters and Oral presentations
15:45-16:00 Closing remarks
16.30 Bus to Frankfurt Airport and downtown