Location & dates EMBL Heidelberg, Germany 2 - 4 Feb 2017
Deadlines Registration closed Abstract submission closed
organiser_NCT

Programme

The poster listings can be downloaded here.

A pdf document of the final programme can be downloaded here.

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Day 1 - Thursday 2 February 2017
TimeSpeaker
12:00-13:30 Registration and light refreshments
13:30-13:45 Opening remarks
13:45-17:30 Session 1: Unleashing endogenous immunity
Chair: Christof von Kalle
13:45-14:15

Ugur Sahin, Johannes Gutenberg University Mainz

14:15-14:30

Heterogeneity and dynamics of the tumor-infiltrating lymphocyte repertoire
Isabel Poschke, DKFZ

14:30-14:45

NOX2-derived oxidative stress promotes melanoma metastasis by inhibiting IFN-gamma producing NK cells
Ebru Aydin, Gothenburg University

14:45-15:15

Coffee Break kindly sponsored by Roche

15:15-15:45

T cell differentiation in chronic infection
Dietmar Zehn, Technical University Munich

15:45-16:15 Targeting the driver mutation IDH1R132H in brain tumors
Michael Platten, German Cancer Research Institute
16:15-17:00 Coffee Break (kindly sponsored by Roche) & Meet the Speakers
17:00-17:30 What do T cells recognize on tumor cells?
John Haanen, Netherlands Cancer Institute
17:30-17:45

Flash talks (1 slide / 2 min each):
Kroon #51, Thiesen #61, Veerman #63, Volkmar #65, Younos #67

17:45-19:00 Poster Session I (odd numbers)
19:00-20:30 Welcome reception with light refreshments
Day 2 - Friday 3 February 2017
TimeSpeaker
09:00-12:00 Session 2: Clinical studies of T cell-based immunotherapies
Chair: Dirk Jäger
09:00-09:30 T Cell-engaging Antibodies for Cancer Therapy
Patrick Baeuerle, MPM Capital
09:30-09:45 High mutational load drives durable remission by targeting programmed death receptor 1 in a patient with metastatic luminal breast cancer
Carlo Fremd, NCT
09:45-10:15

What do we need for Successful Adoptive Immunotherapy of Solid Tumors?
Malcolm Brenner, Texas Children´s Hospital

10:15-10:45 Coffee Break kindly sponsored by Roche
10:45-11:15 Immune Checkpoint Blockade in treatment of advanced Melanoma
Dirk Schadendorf, University Hospital Essen
11:15-11:45 Ton Schumacher, The Netherlands Cancer Institute
1:45-12:00

Immune evasion and PD-1-positive T cell infiltration in DNA mismatch repair-deficient colorectal cancer
Matthias Kloor, University Hospital Heidelberg

12:00-13:45 Lunch
13:45-17:30 Session 3: Markers of effective immune responses
Chair:
13:45-14:15

TCR gene editing of memory stem T cells for cancer treatment
Chiara Bonini, Ospedale San Raffaele - Milano

14:15-14:45

Jérôme Galon, INSERM

14:45-15:00

AT1413: an antibody isolated from a cured Acute Myeloid Leukemia (AML) patient that is highly efficacious against AML in vivo
Greta de Jong, AIMM Therapeutics

15:00-15:30 Genomic analysis of human tumor immunity
Nir Hacohen, Massachusetts General Hospital, Harvard Medical School
15:30-16:15

Coffee Break (kindly sponsored by Roche) & Meet the Speakers

16:15-16:30

Investigation of tumor-reactive T-cell repertoire in the immune infiltrate of metastatic melanoma under immune checkpoint inhibition
Jessica Hassel, University Hospital Heidelberg

16:30-16:45

Immunotherapy for melanoma patients: towards identification of predictive response biomarkers
Michal Harel, Tel Aviv University

16:45-17:00

AML patients cured after allogeneic hematopoietic stem cell transplantation develop antibodies capable of directly killing AML blasts in vitro and in vivo
Gemma Moiset, AIMM Therpeutics

17:00-17:30

Modulating T cell metabolism for cancer immunotherapy
Roger Geiger, Institute for Research in Biomedicine

17:30-17:45 Flash talks (1 slide / 2 min each):
Kather #48, Krall #50, Schneidt #58, Tunali #62
17:45-19:00

Poster Session II (even numbers)

19:00-21:00 Banquet Dinner
21:00-00:00 Conference Party with DJ
Day 3 - Saturday 4 February 2017
TimeSpeaker
09:00-12:15 Session 4: Inducing Immunity
Chair: Ton Schumacher

09:00-09:30 T cell therapies for Hematologic Cancers – Beyond CARs
Catherine M. Bollard, Children's National Health System
09:30-09:45

Oncolytic Measles Virus for Tumor-Specific Vaccination
Christine Engeland, NCT

09:45-10:00

Development of rational immunomodulation strategies for virotherapy
Ruta Veinalde, NCT

10:00-10:30

Adoptive T cell therapy
Thomas Blankenstein, Max-Delbrück Center for Molecular Medicine

10:30-11:00

Coffee Break (kindly sponsored by Roche) & Meet the Speakers

11:00-11:15

BiTE-armed oncolytic measles viruses for cancer immunovirotherapy
Johannes Heidbuechel, DKFZ

11:15-11:30 The molecular basis of CD4+ T-cell help for the cytotoxic T-cell response against cancer
Tomasz Ahrends, Netherlands Cancer Institute
11:30-11:45 Direct detection of predicted tumor neoepitopes by targeted mass spectrometry
Angelika Riemer, DKFZ
11:45-12:15 Crosstalk between the adaptive and innate immune system in metastatic breast cancer
Karin de Visser, Netherlands Cancer Institute
12:15-14:00 Lunch
14:00-17:15 Session 5: Targeting the microenvironment
Chair: Hans-Reimer Rodewald

14:00-14:30

Anti-tumor T cells- you are what you eat
Susan Kaech, Yale School of Medicine

14:30-15:00

The mechanistic basis of cancer immunotherapy
Ira Mellman, Genentech

15:00-15:15

Myeloid Derived Suppressor Cells-Mast Cells Cross-Talk Via C40-CD40L Mediate Tumor Specific Immunosuppression in Prostate Cancer
Elena Jachetti, Fondazione IRCCS

15:15-15:30 Hypoxia induces a new population of tumor-reactive CD8 T cells expressing high levels of PD-1 and IL-10
Telma Lanca, Netherlands Cancer Institute
15:30-16:00 Coffee Break kindly sponsored by Roche
16:00-16:30

Inflammation-induced phenotypic plasticity of tumor and immune cells in disease progression and therapy resistance of melanoma
Thomas Tüting, University of Magdeburg

16:30-16:45

Imaging in cancer immunology: Phenotyping of multiple immune cell subsets in-situ in FFPE tissue sections
Bjoern Wendik, PerkinElmer

16:45-17:00

The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas
Jana Sonner, DKFZ

17:00-17:15 Closing remarks
17:25 Bus departure to downtown Heidelberg & Frankfurt Int. Airport
(tickets for the airport bus are available for 25 EUR at the registration desk)