Location & dates EMBL Heidelberg, Germany 24 - 27 Sep 2017
Deadlines Registration closed Abstract submission closed
organiser_EMBO_Conf_2017

Programme

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Day 1 - Sunday 24 September 2017
TimeSpeaker
13.30 - 15.30 Arrival and Registration with light refreshments
15.30 - 15.40 Opening remarks
15.40 - 16.25

Keynote lecture: Chlamydomonas as a model for centrioles
Susan K. Dutcher, Washington University

16.25 - 19.05

Session 1: Centrosome/SPB Biogenesis
Chair: Chad Pearson, University of Colorado

16.25 - 16.50

g-TuRC independent microtubule organisation at Drosophila centrosomes
Paul Conduit, University of Cambridge

16.50 - 17.15

Reconstitution of functional PCM using purified proteins
Jeff Woodruff, MPI-CBG

17.15 - 17.45

Coffee break

17.45 - 18.10 
Tetrahymena Poc5 and Sfr1 are required for proper basal body patterning and copy number control
Mark Winey, University of California, Davis
18.10 - 18.25 Maintenance of the mitotic pericentriolar material is an autocatalytic process independent of centrioles
Triin Laos, University of Vienna
18:25 - 18:40 Mitotic Centrosome Formation in Flies: Structural and Molecular  Studies of Cnn Scaffold Assembly
Anna Caballe, University of Oxford
18.40 - 19.05

Structural centrosome aberrations promote non cell autonomous invasiveness
Erich Nigg, University of Basel

19.05 - 21.00

Welcome Dinner

21.00 - 23.00

Sneak preview of posters

Day 2 - Monday 25 September 2017
TimeSpeaker
09.00 - 11.15
Session 2: Centrosome/SPB Biogenesis
Chair: Daiju Kitagawa, National Institute of Genetics
09.00 - 09.25 Molecular model of fission yeast centrosome assembly determined by super resolution imaging
Sue Jaspersen, Stowers Institute for Medical Research
09.25 – 09.50

Emerging roles of Tiam1-Rac signalling at the centrosome
Angeliki Malliri, Cancer Research UK Manchester Institute

09.50 - 10.15

Pericentrin regulation of centriole association and separation during M phase
Kunsoo Rhee, Seoul National University

10.15 - 10.30

Mechanism of microtubule-based centrosome cohesion in human cells
Shoji Hata, University of Heidelberg

10.30 – 10.45

Role of human Sfi1 in Centriole biogenesis
Iméne B. Bouhlel, Institut Curie

10.45 - 11.15

Coffee break

11.15 - 13.00

Session 3: Centriole duplication
Chair: Ingrid Hoffmann, German Cancer Research Center
11.15 - 11.40

Cell free dissection of cartwheel assembly mechanisms
Pierre Gönczy, Swiss Federal Institute of Technology Lausanne

11.40 - 12.05 Regulation of Centrosome Assembly: Right Time & Right Place
Monica Bettencourt-Dias, Institute Gulbenkian de Ciência
12.05 – 12.30 Molecular control of centrosome duplication
Andrew Holland, Johns Hopkins University
12.30 – 12.45

Polo-like kinase 4 (PLK4) phosphorylates CEP131 to control centriole satellite integrity
Ryan Denu, University of Wisconsin-Madison

12.45 - 13.00

Underdeveloped cartwheel and no Plk1-mediated centriole reduplication in the absence of daughter centriole microtubules
Jadranka Loncarek, NIH/NCI‑Frederick

13.00 – 14.00

Lunch

14.00 – 16.30

Poster session I

16.30 - 18.30

Session 4: PCM and MT nucleation
Chair: Kayoko Tanaka, University of Leicester

16.30 – 16.55

Microtubule nucleation pathways in mitosis: role and regulation
Isabelle Vernos, CRG and ICREA Barcelona

16.55 - 17.20

Assembly of the gamma-tubulin ring complex
Andreas Merdes, University Toulouse III/CNRS

17.20 - 17.45

Structural insights into centrosome assembly and microtubule nucleation
David A. Agard, HHMI/University of California, San Francisco

17.45 – 18.00

Centrosomal actin regulates microtubule nucleation
Manuel Thery, CEA

18.00 – 18.15

Mto2 multimerization via two independent homodimerization domains underlies architecture of Mto1/2 microtubule nucleation complex
Harish Thakur, University of Edinburgh

18.15 – 18.30 Coffee break
18.30 – 19.30 Career talk
Anthony Hyman, MPI
19.30 – 21.00 Dinner
21.00 – 23.00 After Dinner Drinks at the Roof Top Lounge
Day 3 - Tuesday 26 September 2017
TimeSpeaker
09.00 - 11.00 Session 5: Alternative or modified MTOCs
Chair: Michel Bornens, CNRS Institut Curie
09.00 – 09.25 Mechanisms of centrosome homeostasis
Tim Stearns, Stanford University
09.25 – 09.50 Functional multipotency and inheritance patterns of centrosomes as revealed in trypanosomes
Keith Gull, University of Oxford
09.50 – 10.05

Tissue specific degradation of essential centrosome components reveals distinct populations of microtubules at non-centrosomal MTOCs
Jessica Feldman, Stanford University

10.05 – 10.20

The Centrosome Controls the Number and Spatial Distribution of Microtubules by Negatively Regulating Alternative MTOCs
Fernando Balestra, Cabimer-CSIC

10.20 – 11.00

Coffee break

11.00 - 12.35

Session 6: Basal bodies
Chair: Ciaran Morrison, National University of Ireland

11.00 – 11.25

Strategic Co-opetition of Centrosomes and Cilia 
Meng Fu Bryan Tsou, Memorial Sloan-Kettering Cancer Center

11.25 – 11.50

Super-resolution microscopy on centrioles and cilia
Jung-Chi Liao, IAMS, Academia Sinica

11.50 – 12.05

During centriole to basal body conversion in Drosophila, Cby, Fam92 and Dzip1 form a ternary complex required to build the ciliary transition zone
Bénédicte Duran, University of Lyon-1

12.05 – 12.20

Myosin-Va-mediated preciliary vesicle transportation is required for the initial step of primary cilium assembly
Chien-Ting Wu, National Yang Ming University, Academia Sinica

12.20 – 12.35

Protein interaction analysis provides a map of the spatial and temporal organization of the ciliary gating zone
Daisuke Takao, National Institute of Genetics

12.35 - 13.35 Lunch
13.35 – 16.30

Poster session II

16.30 - 17.50

Session 7: Centrosomes / SPB and signalling
Chair: Ayse K. Caydasi, Koc University

16.30 – 16.55

Centrosome docking to direct secretion
Jane Stinchcombe, University of Cambridge

16.55 – 17.20

Controlling cytokinesis from the SPB
Viesturs Simanis, EPFL Switzerland

17.20 - 17.35

Crosstalk between SPB mitotic entrance and exit scaffolds in S. pombe drives mitotic entry
Kuan Yoow Chan, University of Manchester

17.35 - 17.50

CDK-1 chromatin-mediated recruitment to the SPB controls its insertion into the nuclear envelope
Alfonso Fernandez-Alvarez, National Institutes of Health

17.50 - 19.30

Science Slam

19:30 – 01:00

Conference Dinner and Party

Day 4 - Wednesday 27 September 2017
TimeSpeaker
09.00 - 11.15 Session 8: Development and disease
Chair: Moe Mahjoub, Washington University in St. Louis
09.00 – 09.25 A novel role of Plk4 in regulating centrosome asymmetry and spindle positioning in neural stem cells
Renata Basto, Institut Curie
09.25 – 09.50

Targeting Molecular vulnerabilities of cancer centrosomes to control cancer cell proliferation
Jay Gopalakrishnan, University of Cologne

09.50 – 10.15

Centrosomes clear the way for cytokinesis
Karen Oegema, Ludwig Institute for Cancer Research

10.15 – 10.30

Centrosome and spindle proteins in post-mitotic cells: the NEK7-Eg5 module regulates dendrite morphogenesis in neurons
Jens Lüders, Institute for Research in Biomedicine

10.30 – 10.45

Primary cilia mediate diverse kinase inhibitor resistance mechanisms in cancer
Barbara Tanos, Institute of Cancer Research

10.45 – 11.15

Coffee break

11.15 - 13.15

Session 9: Development and disease
Chair: Helena Soares, University of Lisbon

11.15 – 11.40

Centrosome dysfunction and its link to primordial dwarfism
Fanni Gergely, University of Cambridge

11.40 – 12.05

Drosophila neural stem cells are polarised by their daughter cells
Jens Januschke, University of Dundee

12.05 – 12.30 Spatial control of basal body synthesis and organization in Stentor coeruleus
Wallace Marshall, University of California, San Francisco
12.30 – 12.45

Non-cell autonomous invasion mediated by centrosome amplification
Susana Godinho, Queen Mary University of London

12.45 - 13.00

Regulation of proteostasis by centrosomal proteins
Suzanna Prosser, Lunenfeld-Tanenbaum Research Institute

13.00 – 13.15

Coffee break

13.15 – 14.00

Closing remarks:
Keynote lecture:
Gorab, an unexpected partner of Sas6
David Glover, University of Cambridge

14.00 - 14.30

Poster prize and closing remarks

14.30 - 15.00

Packed lunch and departure

15:15

Frankfurt am Main Airport Shuttle